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TWO SIGMA INVESTMENTS, LP
> SRPT
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Sarepta Therapeutics, Inc. | SRPT | 1,289,198 | 192,055 | 147,638,955,000 | -3,580,265,000 | $114,520.00 |
| 03/31/2023 | Sarepta Therapeutics, Inc. | SRPT | 1,097,143 | 405,737 | 151,219,220,000 | 61,626,831,000 | $137,830.00 |
| 12/31/2022 | Sarepta Therapeutics, Inc. | SRPT | 691,406 | 660,739 | 89,592,389,000 | 89,590,090,000 | $129,580.00 |
| 06/30/2022 | Sarepta Therapeutics, Inc. | SRPT | 30,667 | -262,632 | 2,299,000 | -20,614,000 | $74.97 |
| 03/31/2022 | Sarepta Therapeutics, Inc. | SRPT | 293,299 | -512,962 | 22,913,000 | -49,691,000 | $78.12 |
| 12/31/2021 | Sarepta Therapeutics, Inc. | SRPT | 806,261 | 553,885 | 72,604,000 | 49,264,000 | $90.05 |
| 09/30/2021 | Sarepta Therapeutics, Inc. | SRPT | 252,376 | 231,409 | 23,340,000 | 21,710,000 | $92.48 |
| 06/30/2021 | Sarepta Therapeutics, Inc. | SRPT | 20,967 | -65,300 | 1,630,000 | -4,799,000 | $77.74 |
| 03/31/2021 | Sarepta Therapeutics, Inc. | SRPT | 86,267 | 86,267 | 6,429,000 | 6,429,000 | $74.52 |
| 06/30/2018 | Sarepta Therapeutics, Inc. | SRPT | 0 | -56,203 | 0 | -4,164,000 | |
| 03/31/2018 | Sarepta Therapeutics, Inc. | SRPT | 56,203 | 56,203 | 4,164,000 | 4,164,000 | $74.09 |
| 03/31/2017 | Sarepta Therapeutics, Inc. | SRPT | 0 | -263,229 | 0 | -7,220,000 | |
| 12/31/2016 | Sarepta Therapeutics, Inc. | SRPT | 263,229 | 263,229 | 7,220,000 | 7,220,000 | $27.43 |
| 03/31/2016 | Sarepta Therapeutics, Inc. | SRPT | 0 | -115,518 | 0 | -4,457,000 | |
| 12/31/2015 | Sarepta Therapeutics, Inc. | SRPT | 115,518 | 115,518 | 4,457,000 | 4,457,000 | $38.58 |
| 09/30/2015 | Sarepta Therapeutics, Inc. | SRPT | 89,267 | 89,267 | 2,866,000 | 2,866,000 | $32.11 |
| 06/30/2013 | Sarepta Therapeutics, Inc. | SRPT | 0 | -15,306 | 0 | -395,000 | |
| 03/31/2013 | Sarepta Therapeutics, Inc. | SRPT | 0 | -15,306 | 0 | -395,000 | |
| 12/31/2012 | Sarepta Therapeutics, Inc. | SRPT | 15,306 | 15,306 | 395,000 | 395,000 | $25.81 |
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