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FMR LLC
> AKBA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Akebia Therapeutics, Inc. | AKBA | 613,590 | 0 | 561,435,000 | 217,579,000 | $915.00 |
| 03/31/2023 | Akebia Therapeutics, Inc. | AKBA | 613,590 | -3,528 | 343,856,000 | 343,661,000 | $560.40 |
| 09/30/2022 | Akebia Therapeutics, Inc. | AKBA | 617,118 | -4,126 | 195,000 | -24,000 | $0.32 |
| 06/30/2022 | Akebia Therapeutics, Inc. | AKBA | 621,244 | 397,243 | 219,000 | 58,000 | $0.35 |
| 03/31/2022 | Akebia Therapeutics, Inc. | AKBA | 224,001 | 224,001 | 161,000 | 161,000 | $0.72 |
| 12/31/2021 | Akebia Therapeutics, Inc. | AKBA | 0 | -37 | 0 | -107 | |
| 09/30/2021 | Akebia Therapeutics, Inc. | AKBA | 37 | 37 | 107 | 107 | $2.88 |
| 06/30/2021 | Akebia Therapeutics, Inc. | AKBA | 0 | -280 | 0 | -1,000 | |
| 03/31/2021 | Akebia Therapeutics, Inc. | AKBA | 280 | 280 | 1,000 | 1,000 | $3.57 |
| 12/31/2020 | Akebia Therapeutics, Inc. | AKBA | 0 | -1,200 | 0 | -3,000 | |
| 09/30/2020 | Akebia Therapeutics, Inc. | AKBA | 1,200 | -1,770,367 | 3,000 | -24,055,000 | $2.50 |
| 06/30/2020 | Akebia Therapeutics, Inc. | AKBA | 1,771,567 | 745,500 | 24,058,000 | 16,280,000 | $13.58 |
| 03/31/2020 | Akebia Therapeutics, Inc. | AKBA | 1,026,067 | 861,808 | 7,778,000 | 6,740,000 | $7.58 |
| 12/31/2019 | Akebia Therapeutics, Inc. | AKBA | 164,259 | 57,091 | 1,038,000 | 618,000 | $6.32 |
| 09/30/2019 | Akebia Therapeutics, Inc. | AKBA | 107,168 | -38,074 | 420,000 | -283,000 | $3.92 |
| 06/30/2019 | Akebia Therapeutics, Inc. | AKBA | 145,242 | -66,426 | 703,000 | -1,031,000 | $4.84 |
| 03/31/2019 | Akebia Therapeutics, Inc. | AKBA | 211,668 | -2,500 | 1,734,000 | 550,000 | $8.19 |
| 12/31/2018 | Akebia Therapeutics, Inc. | AKBA | 214,168 | -460,710 | 1,184,000 | -4,775,000 | $5.53 |
| 09/30/2018 | Akebia Therapeutics, Inc. | AKBA | 674,878 | -139,277 | 5,959,000 | -2,166,000 | $8.83 |
| 06/30/2018 | Akebia Therapeutics, Inc. | AKBA | 814,155 | 0 | 8,125,000 | 366,000 | $9.98 |
| 03/31/2018 | Akebia Therapeutics, Inc. | AKBA | 814,155 | 0 | 7,759,000 | -4,347,000 | $9.53 |
| 12/31/2017 | Akebia Therapeutics, Inc. | AKBA | 814,155 | -222,800 | 12,106,000 | -8,291,000 | $14.87 |
| 09/30/2017 | Akebia Therapeutics, Inc. | AKBA | 1,036,955 | 0 | 20,397,000 | 20,382,099 | $19.67 |
| 06/30/2017 | Akebia Therapeutics, Inc. | AKBA | 1,036,955 | 105,100 | 14,901 | -8,558,099 | $0.01 |
| 03/31/2017 | Akebia Therapeutics, Inc. | AKBA | 931,855 | 0 | 8,573,000 | -1,128,000 | $9.20 |
| 12/31/2016 | Akebia Therapeutics, Inc. | AKBA | 931,855 | 0 | 9,701,000 | 1,268,000 | $10.41 |
| 09/30/2016 | Akebia Therapeutics, Inc. | AKBA | 931,855 | 931,855 | 8,433,000 | 8,433,000 | $9.05 |
| 06/30/2016 | Akebia Therapeutics, Inc. | AKBA | 1,688,855 | -300,400 | 12,633,000 | -5,290,000 | $7.48 |
| 03/31/2016 | Akebia Therapeutics, Inc. | AKBA | 1,989,255 | 23,655 | 17,923,000 | -7,473,000 | $9.01 |
| 12/31/2015 | Akebia Therapeutics, Inc. | AKBA | 1,965,600 | 0 | 25,396,000 | 6,408,000 | $12.92 |
| 09/30/2015 | Akebia Therapeutics, Inc. | AKBA | 1,965,600 | 0 | 18,988,000 | -1,238,000 | $9.66 |
| 06/30/2015 | Akebia Therapeutics, Inc. | AKBA | 1,965,600 | 1,241,400 | 20,226,000 | 12,180,000 | $10.29 |
| 03/31/2015 | Akebia Therapeutics, Inc. | AKBA | 724,200 | 0 | 8,046,000 | -384,000 | $11.11 |
| 12/31/2014 | Akebia Therapeutics, Inc. | AKBA | 724,200 | -275,200 | 8,430,000 | -13,687,000 | $11.64 |
| 09/30/2014 | Akebia Therapeutics, Inc. | AKBA | 999,400 | -19,700 | 22,117,000 | -6,204,000 | $22.13 |
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