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FMR LLC
> PBYI
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | PUMA BIOTECHNOLOGY, INC. | PBYI | 63,918 | -3 | 225,631,000 | 28,115,000 | $3,530.01 |
| 03/31/2023 | PUMA BIOTECHNOLOGY, INC. | PBYI | 63,921 | -390 | 197,516,000 | 197,364,000 | $3,090.00 |
| 09/30/2022 | PUMA BIOTECHNOLOGY, INC. | PBYI | 64,311 | -434 | 152,000 | -32,000 | $2.36 |
| 06/30/2022 | PUMA BIOTECHNOLOGY, INC. | PBYI | 64,745 | 53 | 184,000 | -2,000 | $2.84 |
| 03/31/2022 | PUMA BIOTECHNOLOGY, INC. | PBYI | 64,692 | 64,692 | 186,000 | 186,000 | $2.88 |
| 12/31/2020 | PUMA BIOTECHNOLOGY, INC. | PBYI | 0 | -12,768 | 0 | -129,000 | |
| 09/30/2020 | PUMA BIOTECHNOLOGY, INC. | PBYI | 12,768 | -36,600 | 129,000 | -386,000 | $10.10 |
| 06/30/2020 | PUMA BIOTECHNOLOGY, INC. | PBYI | 49,368 | -73,500 | 515,000 | -522,000 | $10.43 |
| 03/31/2020 | PUMA BIOTECHNOLOGY, INC. | PBYI | 122,868 | 0 | 1,037,000 | -38,000 | $8.44 |
| 12/31/2019 | PUMA BIOTECHNOLOGY, INC. | PBYI | 122,868 | -91,700 | 1,075,000 | -1,234,000 | $8.75 |
| 09/30/2019 | PUMA BIOTECHNOLOGY, INC. | PBYI | 214,568 | -74,213 | 2,309,000 | -1,361,000 | $10.76 |
| 06/30/2019 | PUMA BIOTECHNOLOGY, INC. | PBYI | 288,781 | -238,287 | 3,670,000 | -16,775,000 | $12.71 |
| 03/31/2019 | PUMA BIOTECHNOLOGY, INC. | PBYI | 527,068 | -333,198 | 20,445,000 | 2,938,000 | $38.79 |
| 12/31/2018 | PUMA BIOTECHNOLOGY, INC. | PBYI | 860,266 | -521,627 | 17,507,000 | -45,853,000 | $20.35 |
| 09/30/2018 | PUMA BIOTECHNOLOGY, INC. | PBYI | 1,381,893 | -338,401 | 63,360,000 | -38,396,000 | $45.85 |
| 06/30/2018 | PUMA BIOTECHNOLOGY, INC. | PBYI | 1,720,294 | 132,205 | 101,756,000 | -6,313,000 | $59.15 |
| 03/31/2018 | PUMA BIOTECHNOLOGY, INC. | PBYI | 1,588,089 | -120,065 | 108,069,000 | -60,782,000 | $68.05 |
| 12/31/2017 | PUMA BIOTECHNOLOGY, INC. | PBYI | 1,708,154 | -405,816 | 168,851,000 | -84,297,000 | $98.85 |
| 09/30/2017 | PUMA BIOTECHNOLOGY, INC. | PBYI | 2,113,970 | -406,078 | 253,148,000 | 252,927,748 | $119.75 |
| 06/30/2017 | PUMA BIOTECHNOLOGY, INC. | PBYI | 2,520,048 | -1,020,681 | 220,252 | -131,494,748 | $0.09 |
| 03/31/2017 | PUMA BIOTECHNOLOGY, INC. | PBYI | 3,540,729 | 81,410 | 131,715,000 | 25,514,000 | $37.20 |
| 12/31/2016 | PUMA BIOTECHNOLOGY, INC. | PBYI | 3,459,319 | -1,414,644 | 106,201,000 | -220,598,000 | $30.70 |
| 12/12/2016 | PUMA BIOTECHNOLOGY, INC. | PBYI | 3,654,821 | -1,219,142 | 133,218,229 | -193,580,771 | $36.45 |
| 09/30/2016 | PUMA BIOTECHNOLOGY, INC. | PBYI | 4,873,963 | 4,873,963 | 326,799,000 | 326,799,000 | $67.05 |
| 06/30/2016 | PUMA BIOTECHNOLOGY, INC. | PBYI | 4,873,963 | 937 | 145,195,000 | 2,074,000 | $29.79 |
| 03/31/2016 | PUMA BIOTECHNOLOGY, INC. | PBYI | 4,873,026 | 7,664 | 143,121,000 | -238,323,000 | $29.37 |
| 12/31/2015 | PUMA BIOTECHNOLOGY, INC. | PBYI | 4,865,362 | 18,789 | 381,444,000 | 16,206,000 | $78.40 |
| 09/30/2015 | PUMA BIOTECHNOLOGY, INC. | PBYI | 4,846,573 | 23,949 | 365,238,000 | -197,803,000 | $75.36 |
| 06/30/2015 | PUMA BIOTECHNOLOGY, INC. | PBYI | 4,822,624 | 796,826 | 563,041,000 | -387,491,000 | $116.75 |
| 03/31/2015 | PUMA BIOTECHNOLOGY, INC. | PBYI | 4,025,798 | -9,638 | 950,532,000 | 186,745,000 | $236.11 |
| 12/31/2014 | PUMA BIOTECHNOLOGY, INC. | PBYI | 4,035,436 | 1,245,921 | 763,787,000 | 98,293,000 | $189.27 |
| 09/30/2014 | PUMA BIOTECHNOLOGY, INC. | PBYI | 2,789,515 | 1,270,897 | 665,494,000 | 565,265,000 | $238.57 |
| 06/30/2014 | PUMA BIOTECHNOLOGY, INC. | PBYI | 1,518,618 | -774,467 | 100,229,000 | -138,573,000 | $66.00 |
| 03/31/2014 | PUMA BIOTECHNOLOGY, INC. | PBYI | 2,293,085 | -574,538 | 238,802,000 | -58,083,000 | $104.14 |
| 12/31/2013 | PUMA BIOTECHNOLOGY, INC. | PBYI | 2,867,623 | -729,374 | 296,885,000 | 103,871,000 | $103.53 |
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