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FMR LLC
> PACB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 3,730,775 | -637,392 | 49,619,302,000 | -964,072,000 | $13,300.00 |
| 03/31/2023 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 4,368,167 | 4,179,867 | 50,583,374,000 | 50,582,281,000 | $11,580.00 |
| 09/30/2022 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 188,300 | -1,032,423 | 1,093,000 | -4,302,000 | $5.80 |
| 06/30/2022 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 1,220,723 | -258,710 | 5,395,000 | -8,068,000 | $4.42 |
| 03/31/2022 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 1,479,433 | -312,858 | 13,463,000 | -23,207,000 | $9.10 |
| 12/31/2021 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 1,792,291 | 1,528,880 | 36,670,000 | 29,939,000 | $20.46 |
| 09/30/2021 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 263,411 | 73 | 6,731,000 | -2,478,000 | $25.55 |
| 06/30/2021 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 263,338 | -2,712,824 | 9,209,000 | -89,927,000 | $34.97 |
| 03/31/2021 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 2,976,162 | 2,975,982 | 99,136,000 | 99,131,000 | $33.31 |
| 12/31/2020 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 180 | 129 | 5,000 | 4,000 | $27.78 |
| 09/30/2020 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 51 | 51 | 1,000 | 1,000 | $19.61 |
| 09/30/2016 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 0 | -60,000 | 0 | -470,000 | |
| 03/31/2015 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 0 | -60,000 | 0 | -470,000 | |
| 12/31/2014 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 60,000 | 60,000 | 470,000 | 470,000 | $7.83 |
| 12/31/2012 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 0 | -101,000 | 0 | -185,000 | |
| 09/30/2012 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 101,000 | 101,000 | 185,000 | 185,000 | $1.83 |
| 03/31/2012 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 0 | -28 | 0 | -90 | |
| 12/31/2011 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 0 | -28 | 0 | -90 | |
| 09/30/2011 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 28 | -175,972 | 90 | -2,058,910 | $3.21 |
| 06/30/2011 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 176,000 | -2,100 | 2,059,000 | -443,000 | $11.70 |
| 03/31/2011 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 178,100 | 10,200 | 2,502,000 | -169,000 | $14.05 |
| 12/31/2010 | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | PACB | 167,900 | 167,900 | 2,671,000 | 2,671,000 | $15.91 |
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