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BANK OF THE WEST
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,229 | -38 | 354,910,000 | 354,543,000 | $288,779.50 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,267 | 41 | 367,000 | 22,000 | $289.66 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,226 | -34 | 345,000 | 16,000 | $281.40 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,260 | -38 | 329,000 | 44,000 | $261.11 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,298 | -269 | 285,000 | 1,000 | $219.57 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,567 | -61 | 284,000 | -44,000 | $181.24 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,628 | -2,506 | 328,000 | -560,000 | $201.47 |
| 03/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,134 | -324 | 888,000 | -166,000 | $214.80 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,458 | 90 | 1,054,000 | -135,000 | $236.43 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,368 | -2,216 | 1,189,000 | -722,000 | $272.21 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,584 | -319 | 1,911,000 | 268,000 | $290.25 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,903 | -1,012 | 1,643,000 | -90,000 | $238.01 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,915 | -63 | 1,733,000 | 381,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,978 | 340 | 1,352,000 | -49,000 | $169.47 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,638 | -12 | 1,401,000 | -6,000 | $183.42 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 7,650 | -11,064 | 1,407,000 | -1,951,000 | $183.92 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 18,714 | 9,226 | 3,358,000 | 1,529,000 | $179.44 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 9,488 | 596 | 1,829,000 | 318,000 | $192.77 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 8,892 | 792 | 1,511,000 | 191,000 | $169.93 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 8,100 | 1,304 | 1,320,000 | 302,000 | $162.96 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 6,796 | 6,796 | 1,018,000 | 1,018,000 | $149.79 |
| 06/30/2004 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -3,962 | 0 | -335,000 | |
| 09/30/2000 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,962 | 3,962 | 335,000 | 335,000 | $84.55 |
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