Financial Summary (All financials)
| In millions, except per share items | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 | Dec-31-14 |
| Revenues | 1,375.1 | 664.0 | 1,163.4 | 1,097.9 | 1,001.1 | 799.2 | 789.4 | 848.9 |
| Revenue growth | 107.1% | -42.9% | 6.0% | 9.7% | 25.3% | 1.2% | -7.0% | -5.1% |
| Cost of goods sold | 49.8 | 52.6 | 50.9 | 47.8 | 47.9 | 41.3 | 44.8 | 43.6 |
| Gross profit | 1,325.3 | 611.5 | 1,112.5 | 1,050.1 | 953.3 | 757.9 | 744.6 | 805.3 |
| Gross margin | 96.4% | 92.1% | 95.6% | 95.6% | 95.2% | 94.8% | 94.3% | 94.9% |
| Selling, general and administrative | 1,040.9 | 1,020.4 | 967.9 | 887.9 | 853.3 | 811.1 | 792.5 | 427.6 |
| Research and development | | | | | | | | |
| General and administrative | 644.2 | 621.5 | 587.4 | 540.6 | 518.4 | 442.8 | 109.9 | 33.2 |
| EBITA | 284.3 | -408.9 | 144.6 | 428.8 | 338.3 | 214.5 | -47.9 | 32.4 |
| EBITA margin | 20.7% | -61.6% | 12.4% | 39.1% | 33.8% | 26.8% | -6.1% | 3.8% |
| Amortization of intangibles | 16.7 | 19.9 | 20.8 | 22.1 | 22.4 | 19.8 | 24.2 | 26.8 |
| EBIT | 267.7 | -428.9 | 123.8 | 406.8 | 315.9 | 194.7 | -72.1 | 5.6 |
| EBIT margin | 19.5% | -64.6% | 10.6% | 37.1% | 31.6% | 24.4% | -9.1% | 0.7% |
| Pre-tax income | 568.1 | -124.7 | 392.7 | 382.1 | 308.4 | 186.9 | 169.8 | 242.2 |
| Income taxes | 104.8 | -79.6 | 65.4 | 58.3 | 92.8 | 37.6 | 38.3 | 66.5 |
| Tax rate | 18.5% | 63.8% | 16.6% | 15.3% | 30.1% | 20.1% | 22.6% | 27.4% |
| Net income | 463.2 | -45.2 | 327.4 | 323.8 | 215.6 | 149.3 | 131.5 | 175.7 |
| Net margin | 33.7% | -6.8% | 28.1% | 29.5% | 21.5% | 18.7% | 16.7% | 20.7% |
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| Diluted EPS | $5.32 | ($0.52) | $3.78 | $3.79 | $2.54 | $1.92 | $1.68 | $2.14 |
| Shares outstanding (diluted) | 87.0 | 86.5 | 86.6 | 85.5 | 85.0 | 77.9 | 78.3 | 82.0 |
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| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |
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