CYPRESS BIOSCIENCE INC (CYPB) [Rocket]

Date	Name	Title	Type	Security	Shares	Price	Value	Ownership	Reported
12/28/2010	KRANZLER JAY D	CEO	Exercise	Stock Options (right to buy)	25k	$3.25	$81.2k		12/28/2010
12/28/2010	KRANZLER JAY D	CEO	Sale	Common Stock	25k	$6.46	$161.5k	By Trust	12/28/2010
12/28/2010	KRANZLER JAY D	CEO	Exercise	Common Stock	25k	$3.25	$81.2k	By Trust	12/28/2010
12/23/2010	KRANZLER JAY D	CEO	Exercise	Stock Options (right to buy)	152.5k	$3.25	$495.5k		12/23/2010
12/23/2010	KRANZLER JAY D	CEO	Sale	Common Stock	152.5k	$6.45	$983.4k	By Trust	12/23/2010
12/23/2010	KRANZLER JAY D	CEO	Exercise	Common Stock	152.5k	$3.25	$495.5k	By Trust	12/23/2010
12/20/2010	Srinivas G. Rao	Chief Scientific Officer	Sale	Common Stock	7.5k	$6.44	$48.3k		12/20/2010
12/20/2010	Srinivas G. Rao	Chief Scientific Officer	Exercise	Stock Option (right to buy)	7.5k	$4.75	$35.6k		12/20/2010
07/15/2010	GENDREAU R MICHAEL	Chief Medical Officer	Purchase	Common Stock	10k	$2.13	$21.3k		07/15/2010
07/08/2010	GENDREAU R MICHAEL	Chief Medical Officer	Purchase	Common Stock	5k	$2.21	$11k		07/08/2010
01/04/2010	HAWLEY ROGER	Director	Grant	Stock Options (right to buy)	15k	$6.03	$90.4k		01/04/2010
01/04/2010	GENDREAU R MICHAEL	Chief Medical Officer	Grant	Stock Option (right to buy)	40k	$6.03	$241.2k		01/04/2010
01/04/2010	JOHNSON SABRINA MARTUCCI	Exec VP, CBO & CFO	Grant	Stock Option (right to buy)	78k	$6.03	$470.3k		01/04/2010
01/04/2010	KRANZLER JAY D	CEO	Grant	Common Stock	100k	$0.00	$0		01/04/2010
01/04/2010	MCGARITY JON W	Director	Grant	Stock Option (right to buy)	15k	$6.03	$90.4k		01/04/2010
01/04/2010	Kalali Amir H	Director	Grant	Stock Options (right to buy)	15k	$6.03	$90.4k		01/04/2010
01/04/2010	MILLON JEAN PIERRE	Director	Grant	Stock Option (right to buy)	15k	$6.03	$90.4k		01/04/2010
01/04/2010	Petree Daniel H	Director	Grant	Stock Option (right to buy)	15k	$6.03	$90.4k		01/04/2010
01/04/2010	Srinivas G. Rao	Chief Scientific Officer	Grant	Stock Option (right to buy)	27k	$6.03	$162.8k		01/04/2010
01/04/2010	WHEELER DENISE	General Counsel	Grant	Stock Option (right to buy)	27.8k	$6.03	$167.3k		01/04/2010
01/04/2010	MOLINOFF PERRY B	Director	Grant	Stock Option (right to buy)	15k	$6.03	$90.4k		01/04/2010
01/04/2010	Nova Tina Susan	Director	Grant	Stock Option (right to buy)	15k	$6.03	$90.4k		01/04/2010
11/09/2009	Walsh Michael	Exec VP & CCO	Purchase	Common Stock	5k	$6.00	$30k		11/09/2009
08/03/2009	KRANZLER JAY D	CEO	Exercise	Stock Options (right to buy)	75k	$2.51	$188.2k		08/03/2009
08/03/2009	KRANZLER JAY D	CEO	Sale	Common Stock	75k	$8.69	$651.8k	By Trust	08/03/2009
08/03/2009	KRANZLER JAY D	CEO	Exercise	Common Stock	75k	$2.51	$188.2k	By Trust	08/03/2009