| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/02/2023 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 5.7k | $74.12 | $421.1k | | 06/02/2023 |
| 03/02/2023 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 2.9k | $65.32 | $187.5k | | 03/02/2023 |
| 01/03/2023 | Axsome Therapeutics, Inc. | AXSM | Exercise | Stock Option (Right to Buy) | 17.5k | $1.30 | $22.8k | | 01/03/2023 |
| 06/03/2022 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 17k | $25.53 | $433.4k | | 06/03/2022 |
| 03/15/2022 | Axsome Therapeutics, Inc. | AXSM | Exercise | Stock Option (Right to Buy) | 3.5k | $1.30 | $4.5k | | 03/15/2022 |
| 03/04/2022 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 2.8k | $29.91 | $83.7k | | 03/04/2022 |
| 11/18/2021 | Axsome Therapeutics, Inc. | AXSM | Purchase | Common Stock | 409 | $35.07 | $14.3k | See Footnote | 11/18/2021 |
| 11/18/2021 | Axsome Therapeutics, Inc. | AXSM | Purchase | Common Stock | 1k | $35.10 | $35.8k | See Footnote | 11/18/2021 |
| 06/04/2021 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 7.3k | $61.32 | $449.2k | | 06/04/2021 |
| 05/12/2021 | Axsome Therapeutics, Inc. | AXSM | Purchase | Common Stock | 500 | $58.15 | $29.1k | See Footnote | 05/12/2021 |
| 03/05/2021 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 1.2k | $65.02 | $78.1k | | 03/05/2021 |
| 08/19/2020 | Axsome Therapeutics, Inc. | AXSM | Gift | Common Stock | 398k | $0.00 | $0 | | 08/19/2020 |
| 08/19/2020 | Axsome Therapeutics, Inc. | AXSM | Gift | Common Stock | 398k | $0.00 | $0 | By Whale Island, LP | 08/19/2020 |
| 06/29/2020 | Axsome Therapeutics, Inc. | AXSM | Purchase | Common Stock | 650 | $78.50 | $51k | | 06/29/2020 |
| 06/05/2020 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 13k | $77.38 | $1M | | 06/05/2020 |
| 03/17/2020 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 3.3k | $45.14 | $149.3k | | 03/17/2020 |
| 06/26/2019 | Axsome Therapeutics, Inc. | AXSM | Purchase | Common Stock | 15.8k | $23.10 | $365k | | 06/25/2019 |
| 06/25/2019 | Axsome Therapeutics, Inc. | AXSM | Purchase | Common Stock | 400 | $23.25 | $9.3k | | 06/25/2019 |
| 06/07/2019 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 13k | $22.03 | $286.4k | | 06/07/2019 |
| 05/13/2019 | Axsome Therapeutics, Inc. | AXSM | Purchase | Common Stock | 4.6k | $21.44 | $99.7k | | 05/13/2019 |
| 03/19/2019 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 25.7k | $12.95 | $332.2k | | 03/19/2019 |
| 03/19/2019 | Axsome Therapeutics, Inc. | AXSM | Purchase | Common Stock | 5.1k | $12.18 | $62.1k | See Footnote | 03/19/2019 |
| 06/01/2018 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Options (right to buy) | 13k | $3.45 | $44.8k | | 06/01/2018 |
| 03/12/2018 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 27.3k | $2.85 | $77.8k | | 03/12/2018 |
| 03/15/2017 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 26.5k | $4.95 | $131k | | 03/15/2017 |
| 03/15/2017 | Axsome Therapeutics, Inc. | AXSM | Grant | Stock Option (Right to Buy) | 11k | $4.95 | $54.4k | | 03/15/2017 |