| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 12/09/2022 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Purchase | Common Stock | 10k | $0.60 | $6k | ERIC FORMAN REVOCABLE TRUST | 12/09/2022 |
| 12/09/2022 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Purchase | Common Stock | 5k | $0.63 | $3.1k | ERIC FORMAN REVOCABLE TRUST | 12/09/2022 |
| 12/09/2022 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Purchase | Common Stock | 1.1k | $0.63 | $700.6 | ERIC FORMAN REVOCABLE TRUST | 12/09/2022 |
| 11/22/2022 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Purchase | Common Stock | 2.5k | $0.56 | $1.4k | Eric Forman Revocable Trust | 11/21/2022 |
| 11/21/2022 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Purchase | Common Stock | 1.5k | $0.56 | $815.9 | Eric Forman Revocable Trust | 11/21/2022 |
| 11/18/2022 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Purchase | Common Stock | 6.1k | $0.56 | $3.4k | Eric Forman Revocable Trust | 11/17/2022 |
| 11/18/2022 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Purchase | Common Stock | 2.5k | $0.56 | $1.4k | Eric Forman Revocable Trust | 11/17/2022 |
| 11/18/2022 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Purchase | Common Stock | 7.6k | $0.57 | $4.3k | Eric Forman Revocable Trust | 11/17/2022 |
| 11/17/2022 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Purchase | Common Stock | 4.9k | $0.54 | $2.6k | Eric Forman Revocable Trust | 11/17/2022 |
| 11/06/2022 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Grant | | 200k | $2.00 | $400k | | 11/06/2022 |
| 12/17/2021 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Payment of Exercise | Common Stock | 1.3M | $0.00 | $0 | Trustee under the John and Barbara Kovach 2015 Trust | 12/17/2021 |
| 04/22/2021 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Exercise | Common Stock | 16.7k | $0.90 | $15k | | 04/22/2021 |
| 01/04/2021 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Gift | Common Stock | 2.4k | $0.00 | $0 | | 01/04/2021 |
| 01/04/2021 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Grant | Warrants to Purchase Common Stock | 1.3k | $5.70 | $7.2k | | 01/04/2021 |
| 12/30/2020 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Grant | Warrants to Purchase Common Stock | 4k | $5.70 | $22.8k | | 12/30/2020 |
| 12/30/2020 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Gift | Common Stock | 2.9k | $0.00 | $0 | | 12/30/2020 |
| 02/19/2016 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Purchase | Common stock | 10k | $0.30 | $3k | | 02/17/2016 |
| 02/17/2016 | LIXTE BIOTECHNOLOGY HOLDINGS, INC. | LIXT | Purchase | Common stock | 43.5k | $0.30 | $13k | | 02/17/2016 |