| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 05/03/2019 | Alliqua BioMedical, Inc. | ADYX | Grant | Common Stock | 85.3k | $0.00 | $0 | By Trust | 05/03/2019 |
| 05/03/2019 | Alliqua BioMedical, Inc. | ADYX | Grant | Stock Option (Right to Buy) | 396 | $1.39 | $550.4 | By Trust | 05/03/2019 |
| 05/03/2019 | Alliqua BioMedical, Inc. | ADYX | Grant | Stock Option (Right to Buy) | 55.9k | $3.06 | $171k | By Trust | 05/03/2019 |
| 12/11/2017 | Ocera Therapeutics, Inc. | OCRX | Disposition | Stock Option (Right to Buy) | 12.5k | $2.26 | $28.2k | | 12/11/2017 |
| 12/11/2017 | Ocera Therapeutics, Inc. | OCRX | Disposition | Common Stock | 344.7k | $1.52 | $524k | By Trust | 12/11/2017 |
| 12/11/2017 | Ocera Therapeutics, Inc. | OCRX | Disposition | Common Stock | 12k | $1.52 | $18.2k | By Trust | 12/11/2017 |
| 12/11/2017 | Ocera Therapeutics, Inc. | OCRX | Disposition | Common Stock | 12.5k | $1.52 | $19k | | 12/11/2017 |
| 12/11/2017 | Ocera Therapeutics, Inc. | OCRX | Disposition | Stock Option (Right to Buy) | 3k | $1.84 | $5.5k | | 12/11/2017 |
| 12/11/2017 | Ocera Therapeutics, Inc. | OCRX | Disposition | Stock Option (Right to Buy) | 20k | $7.85 | $157k | | 12/11/2017 |
| 12/11/2017 | Ocera Therapeutics, Inc. | OCRX | Disposition | Stock Option (Right to Buy) | 10k | $7.84 | $78.4k | | 12/11/2017 |
| 12/11/2017 | Ocera Therapeutics, Inc. | OCRX | Disposition | Stock Option (Right to Buy) | 10k | $3.76 | $37.6k | | 12/11/2017 |
| 06/20/2017 | Ocera Therapeutics, Inc. | OCRX | Grant | Common Stock | 12.5k | $0.00 | $0 | | 06/20/2017 |
| 11/01/2016 | Tobira Therapeutics, Inc. | TBRA | Disposition | Employee Stock Option (Right to Buy) | 17.8k | $7.91 | $140.6k | | 11/01/2016 |
| 11/01/2016 | Tobira Therapeutics, Inc. | TBRA | Disposition | Employee Stock Option (Right to Buy) | 15.5k | $16.52 | $256.1k | | 11/01/2016 |
| 11/01/2016 | Tobira Therapeutics, Inc. | TBRA | Disposition | Employee Stock Option (Right to Buy) | 4.3k | $2.96 | $12.8k | | 11/01/2016 |
| 11/01/2016 | Tobira Therapeutics, Inc. | TBRA | Other | Common Stock, par value $0.001 | 243.7k | $0.00 | $0 | By Eckard Weber, M.D., Trustee of the Eckard Weber Living Trust UTA dated November 20, 2007 | 11/01/2016 |
| 06/14/2016 | Ocera Therapeutics, Inc. | OCRX | Grant | | 12.5k | $2.26 | $28.2k | | 06/14/2016 |
| 01/12/2016 | Tobira Therapeutics, Inc. | TBRA | Grant | Stock Options (right to buy) | 17.8k | $7.91 | $140.6k | | 01/12/2016 |
| 01/04/2016 | Ocera Therapeutics, Inc. | OCRX | Exercise | Stock Option (Right to Buy) | 12k | $0.92 | $11k | | 01/04/2016 |
| 01/04/2016 | Ocera Therapeutics, Inc. | OCRX | Gift | Common Stock | 12k | $0.00 | $0 | | 01/04/2016 |
| 07/09/2015 | Tobira Therapeutics, Inc. | TBRA | Grant | Stock Options (right to buy) | 15.5k | $16.52 | $256.1k | | 07/09/2015 |
| 06/18/2015 | Ocera Therapeutics, Inc. | OCRX | Grant | | 10k | $3.76 | $37.6k | | 06/18/2015 |
| 06/09/2015 | Orexigen Therapeutics, Inc. | OREXQ | Grant | Stock Option (right to buy) | 50k | $4.63 | $231.5k | | 06/09/2015 |
| 05/04/2015 | Tobira Therapeutics, Inc. | TBRA | Grant | Stock Options (right to buy) | 4.3k | $0.00 | $0 | | 05/04/2015 |
| 05/04/2015 | Tobira Therapeutics, Inc. | TBRA | Grant | | 243.7k | $0.00 | $0 | By Eckard Weber, M.D., Trustee of the Eckard Weber Living Trust UTA dated November 20, 2007 | 05/04/2015 |
| 05/04/2015 | Tobira Therapeutics, Inc. | TBRA | Grant | Stock Options (right to buy) | 4.3k | $0.00 | $0 | | 05/04/2015 |
| 05/04/2015 | Tobira Therapeutics, Inc. | TBRA | Grant | Common Stock | 47.6k | $0.00 | $0 | By DP VII Associates, L.P. | 05/04/2015 |
| 05/04/2015 | Tobira Therapeutics, Inc. | TBRA | Grant | Common Stock | 3.6M | $0.00 | $0 | By Domain Partners VII, L.P. | 05/04/2015 |
| 05/04/2015 | Tobira Therapeutics, Inc. | TBRA | Grant | Common Stock | 36.2k | $0.00 | $0 | By Domain Associates, L.L.C. | 05/04/2015 |
| 05/04/2015 | Tobira Therapeutics, Inc. | TBRA | Grant | Common Stock | 243.7k | $0.00 | $0 | By Eckard Weber, M.D., Trustee of the Eckard Weber Living Trust UTA dated November 20, 2007 | 05/04/2015 |
| 01/16/2015 | Atara Biotherapeutics, Inc. | ATRA | Grant | Non-Qualified Stock Option (Right to Buy) | 25k | $25.15 | $628.8k | | 01/16/2015 |
| 06/27/2014 | Orexigen Therapeutics, Inc. | OREXQ | Grant | Stock Option (right to buy) | 50k | $5.97 | $298.5k | | 06/27/2014 |
| 06/11/2014 | Ocera Therapeutics, Inc. | OCRX | Grant | | 10k | $7.84 | $78.4k | | 06/11/2014 |
| 08/30/2013 | Ocera Therapeutics, Inc. | OCRX | Grant | | 20k | $7.85 | $157k | | 12/19/2013 |
| 07/15/2013 | Ocera Therapeutics, Inc. | OCRX | Grant | Common Stock | 344.7k | $0.00 | $0 | | 07/15/2013 |
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