| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 05/19/2023 | CULLEN/FROST BANKERS, INC. | CFR | Exercise | Common Stock, $0.01 par value | 8.1k | $71.39 | $576.8k | | 05/19/2023 |
| 05/19/2023 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 4k | $100.70 | $404.5k | | 05/19/2023 |
| 05/19/2023 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 2.6k | $101.70 | $264.4k | | 05/19/2023 |
| 05/17/2023 | CULLEN/FROST BANKERS, INC. | CFR | Gift | Common Stock, $0.01 par value | 25k | $0.00 | $0 | Through Trust [Legacy Trust] | 05/16/2023 |
| 05/17/2023 | CULLEN/FROST BANKERS, INC. | CFR | Gift | Common Stock, $0.01 par value | 8.3k | $0.00 | $0 | Through Trust [Legacy Trust fbo Thomas C. Frost III] | 05/16/2023 |
| 05/17/2023 | CULLEN/FROST BANKERS, INC. | CFR | Gift | Common Stock, $0.01 par value | 8.3k | $0.00 | $0 | Through Trust [Legacy Trust fbo Donald B. Frost] | 05/16/2023 |
| 05/16/2023 | CULLEN/FROST BANKERS, INC. | CFR | Acquisition (by will) | Common Stock, $0.01 par value | 30.8k | $0.00 | $0 | Through Trust [Family Trust-B fbo Thomas C. Frost III] | 05/16/2023 |
| 05/16/2023 | CULLEN/FROST BANKERS, INC. | CFR | Disposition (by will) | Common Stock, $0.01 par value | 92.3k | $0.00 | $0 | Through Trust [Marital Trust-B] | 05/16/2023 |
| 05/16/2023 | CULLEN/FROST BANKERS, INC. | CFR | Gift | Common Stock, $0.01 par value | 66k | $0.00 | $0 | Through Trust [Legacy Trust] | 05/16/2023 |
| 05/16/2023 | CULLEN/FROST BANKERS, INC. | CFR | Gift | Common Stock, $0.01 par value | 22k | $0.00 | $0 | Through Trust [Legacy Trust fbo Thomas C. Frost III] | 05/16/2023 |
| 03/07/2023 | CULLEN/FROST BANKERS, INC. | CFR | Grant | Common Stock, $0.01 par value | 1.9k | $0.00 | $0 | | 03/07/2023 |
| 03/07/2023 | CULLEN/FROST BANKERS, INC. | CFR | Payment of Exercise | Common Stock, $0.01 par value | 465 | $127.72 | $59.4k | | 03/07/2023 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 11.5k | $127.86 | $1.5M | | 08/04/2022 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 5.9k | $128.67 | $762k | | 08/04/2022 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 517 | $129.78 | $67.1k | | 08/04/2022 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 78 | $130.69 | $10.2k | | 08/04/2022 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 61.5k | $127.86 | $7.9M | Through Trust | 08/04/2022 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 31.7k | $128.67 | $4.1M | Through Trust | 08/04/2022 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 2.8k | $129.78 | $359.6k | Through Trust | 08/04/2022 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 418 | $130.69 | $54.6k | Through Trust | 08/04/2022 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 727 | $127.86 | $93k | Through Estate | 08/04/2022 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 375 | $128.67 | $48.3k | Through Estate | 08/04/2022 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 33 | $129.78 | $4.3k | Through Estate | 08/04/2022 |
| 08/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 5 | $130.69 | $653.4 | Through Estate | 08/04/2022 |
| 08/03/2022 | CULLEN/FROST BANKERS, INC. | CFR | Acquisition (by will) | Common Stock, $0.01 par value | 450 | $0.00 | $0 | Through Estate | 08/04/2022 |
| 08/03/2022 | CULLEN/FROST BANKERS, INC. | CFR | Disposition (by will) | Common Stock, $0.01 par value | 31.8k | $0.00 | $0 | Through Trust | 08/04/2022 |
| 05/09/2022 | CULLEN/FROST BANKERS, INC. | CFR | Disposition (by will) | Common Stock, $0.01 par value | 250.8k | $0.00 | $0 | Through Trust | 08/04/2022 |
| 05/09/2022 | CULLEN/FROST BANKERS, INC. | CFR | Acquisition (by will) | Common Stock, $0.01 par value | 690 | $0.00 | $0 | Through Estate | 08/04/2022 |
| 03/08/2022 | CULLEN/FROST BANKERS, INC. | CFR | Grant | Common Stock, $0.01 par value | 1.8k | $0.00 | $0 | | 03/08/2022 |
| 03/08/2022 | CULLEN/FROST BANKERS, INC. | CFR | Payment of Exercise | Common Stock, $0.01 par value | 714 | $133.54 | $95.3k | | 03/08/2022 |
| 02/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Exercise | Employee Stock Option (right to buy) | 10.5k | $54.56 | $572.3k | | 02/04/2022 |
| 02/04/2022 | CULLEN/FROST BANKERS, INC. | CFR | Sale | Common Stock, $0.01 par value | 6.6k | $139.33 | $919.7k | | 02/04/2022 |
| 10/26/2021 | CULLEN/FROST BANKERS, INC. | CFR | Grant | Restricted Stock Units | 1.5k | $0.00 | $0 | | 10/26/2021 |
| 10/24/2021 | CULLEN/FROST BANKERS, INC. | CFR | Exercise | Restricted Stock Units | 1.6k | $0.00 | $0 | | 10/24/2021 |
| 10/24/2021 | CULLEN/FROST BANKERS, INC. | CFR | Payment of Exercise | Common Stock, $0.01 par value | 607 | $131.31 | $79.7k | | 10/24/2021 |
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