| In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 |
| | 20-F | 20-F | 20-F | 20-F |
| Turnover | | | | |
| Cost of sales | | | | |
| Gross profit | | | | |
| Selling, general and administration | | | | |
| Research and development | | | | |
| Royalty income | | | | |
| Other operating (expense)/income | | | | |
| Operating profit | | | | |
| Finance income | | | | |
| Finance expense | | | | |
| Loss on disposal of interest in associates | | -36 | | |
| |
| Share of after tax (loss)/profits of associates and joint ventures | | | | |
| Profit before taxation | | | | |
| Taxation | | | | |
| Profit after taxation from continuing operations | | | | |
| Profit after taxation from discontinued operations and other gains/(losses) from the demerger | 3,049 | 1,580 | 1,285 | |
| Re-measurement of discontinued operations distributed to shareholders on demerger | 7,651 | | | |
| |
| Profit after taxation from discontinued operations | | | | |
| Share of after-tax losses | | | | |
| Profit attributable to non-controlling interests from continuing operations | | | | |
| Profit attributable to shareholders from continuing operations | | | | |
| Profit attributable to non-controlling interests from discontinued operations | | | | |
| Profit attributable to shareholders from discontinued operations | | | | |
| Total profit attributable to non-controlling interests | | | | |
| Total profit attributable to shareholders | | | | |
| Total profit after taxation for the year | | | | |
| Basic earnings per share (pence) from continuing operations | | | | |
| Basic earnings per share (pence) from discontinued operations | | | | |
| Total Basic earnings per share (pence) | | | | |
| Diluted earnings per share (pence) from continued operations | | | | |
| Diluted earnings per share (pence) from discontinued operations | | | | |
| Total diluted earnings per share (pence) | | | | |