Overview Financials News + Filings Key Docs Charts Ownership Insiders
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| In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 |
| | 10-K | 10-K | 10-K | 10-K/A | 10-K | 10-K | 10-K | 10-K |
| Operating expenses: | | | | | | | | |
| Research and development | 34.3 | 15.6 | 25.6 | 18.3 | 17.0 | 18.7 | 25.5 | 23.0 |
| General and administrative | 19.2 | 14.8 | 11.8 | 8.8 | 9.3 | 8.9 | 10.1 | 8.6 |
| Total operating expenses | 53.5 | 195.0 | 37.4 | 27.1 | 26.4 | 27.6 | 35.6 | 31.7 |
| Loss from operations | -53.5 | -195.0 | -37.4 | -27.1 | -26.4 | -27.1 | -35.6 | -31.7 |
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| Other income (expense): | | | | | | | | |
| Interest and investment income | 1.7 | 0.1 | 0.2 | 0.8 | 0.4 | 0.2 | 0.2 | |
| Other expense, net | -0.1 | -0.1 | -0.1 | -0.1 | 0.2 | 0.0 | 0.1 | 0.0 |
| Total other income, net | 1.7 | 0.1 | 0.1 | 0.8 | 0.5 | -0.3 | -0.5 | -1.0 |
| Net loss | -51.8 | -194.9 | -37.3 | -26.3 | -25.9 | -27.4 | -36.1 | -32.6 |
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| Net loss per share attributable to common shareholders - basic | ($3.55) | ($24.58) | ($12.20) | ($2.35) | ($5.12) | ($12.62) | ($2.22) | ($4.06) |
| Net loss per share attributable to common shareholders - diluted | ($3.55) | ($24.58) | ($12.20) | ($2.35) | ($5.12) | ($12.62) | ($2.22) | ($4.06) |
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| Weighted-average common shares outstanding used in net loss per share - basic | 14.6 | 8.9 | 3.1 | 11.2 | 5.1 | 2.2 | 16.2 | 8.0 |
| Weighted-average common shares outstanding used in net loss per share - diluted | 14.6 | 8.9 | 3.1 | | | | | |
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