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| In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 |
| | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
| Revenues: |
| U.S. Operations | 1,601.3 | 1,444.0 | 1,194.2 | 1,171.9 | 1,112.3 | 1,043.9 | 958.5 | 826.4 |
| Asia | 1,322.9 | 1,235.1 | | | | | | |
| Western European Operations | 996.8 | 1,041.3 | 889.9 | 876.5 | 895.8 | 844.6 | 817.1 | 620.1 |
| Swiss Operations | 1,016.1 | 997.6 | 823.8 | 797.2 | 762.6 | 697.0 | 655.7 | 133.7 |
| Other | | | 177.4 | 163.1 | 165.0 | 139.5 | 77.0 | 815.3 |
| Total revenues [+] | 3,919.7 | 3,717.9 | 3,085.2 | 3,008.7 | 2,935.6 | 2,725.1 | 2,508.3 | 2,395.4 |
| Products | | | | | | | | 1,865.9 |
| Services | | | | | | | | 529.6 |
| Revenue growth [+] | 5.4% | 20.5% | 2.5% | 2.5% | 7.7% | 8.6% | 4.7% | -3.6% |
| U.S. Operations | 10.9% | 20.9% | 1.9% | 5.4% | 6.5% | 8.9% | 16.0% | -2.5% |
| Asia | 7.1% | | | | | | | |
| Western European Operations | -4.3% | 17.0% | 1.5% | -2.2% | 6.1% | 3.4% | 31.8% | -31.3% |
| Swiss Operations | 1.8% | 21.1% | 3.3% | 4.5% | 9.4% | 6.3% | 390.5% | -80.6% |
| Chinese Operations | 8.1% | 34.2% | 3.0% | 0.2% | 12.0% | 13.1% | 61.1% | -35.1% |
| Cost of goods sold [+] | 1,611.7 | 1,546.4 | 1,284.1 | 1,267.4 | 1,251.2 | 1,149.3 | 1,070.5 | 1,043.5 |
| Cost of product sales | | | | | | | | 744.9 |
| Cost of services | | | | | | | | 298.6 |
| Gross profit | 2,308.0 | 2,171.6 | 1,801.0 | 1,741.2 | 1,684.4 | 1,575.8 | 1,437.7 | 1,352.0 |
| Gross margin | 58.9% | 58.4% | 58.4% | 57.9% | 57.4% | 57.8% | 57.3% | 56.4% |
| Selling, general and administrative | 938.5 | 944.0 | 820.2 | 819.2 | 812.8 | 794.9 | 745.4 | 700.8 |
| Research and development | 177.1 | 169.8 | 140.1 | 144.0 | 141.1 | 128.3 | 119.2 | 119.1 |
| Other operating expenses | 2,207.4 | 1,961.8 | 1,554.2 | 1,412.5 | 47.5 | 42.7 | 36.1 | 31.0 |
| EBITDA [+] | -901.9 | -795.9 | -614.7 | -545.7 | 767.7 | 686.0 | 605.9 | 565.2 |
| EBITDA growth | 13.3% | 29.5% | 12.6% | -171.1% | 11.9% | 13.2% | 7.2% | 4.6% |
| EBITDA margin | -23.0% | -21.4% | -19.9% | -18.1% | 26.2% | 25.2% | 24.2% | 23.6% |
| Depreciation | 86.5 | 85.6 | 83.0 | 73.6 | 70.4 | 64.6 | 60.5 | 57.7 |
| EBITA | -988.5 | -881.5 | -697.7 | -619.3 | 697.3 | 621.4 | 545.4 | 507.5 |
| EBITA margin | -25.2% | -23.7% | -22.6% | -20.6% | 23.8% | 22.8% | 21.7% | 21.2% |
| Amortization of intangibles | 26.5 | 22.5 | 15.7 | 15.1 | 14.3 | 11.5 | 8.3 | 6.3 |
| EBIT [+] | -1,015.0 | -904.0 | -713.4 | -634.4 | 683.0 | 609.9 | 537.1 | 501.2 |
| EBIT growth | 12.3% | 26.7% | 12.5% | -192.9% | 12.0% | 13.6% | 7.2% | 4.9% |
| EBIT margin | -25.9% | -24.3% | -23.1% | -21.1% | 23.3% | 22.4% | 21.4% | 20.9% |
| Non-recurring items | 9.6 | 5.2 | 10.5 | 15.8 | 18.4 | 12.8 | 6.2 | 11.1 |
| Interest expense | 55.4 | 43.2 | 38.6 | 37.4 | 34.5 | 32.8 | 28.0 | 27.5 |
| Interest expense | 55.4 | 43.2 | 38.6 | 37.4 | 34.5 | 32.8 | 28.0 | 27.5 |
| Other income (expense), net | 9.3 | 3.1 | 13.8 | 6.2 | 21.8 | 9.9 | 1.3 | 0.9 |
| Pre-tax income | -1,070.6 | -949.4 | -748.7 | -681.4 | 651.9 | 574.2 | 504.2 | 463.4 |
| Income taxes | 198.1 | 180.4 | 146.0 | 120.3 | 139.2 | 198.3 | 119.8 | 110.6 |
| Tax rate | | | | | 21.4% | 34.5% | 23.8% | 23.9% |
| Net income | 872.5 | 769.0 | 602.7 | 561.1 | 512.6 | 376.0 | 384.4 | 352.8 |
| Net margin | 22.3% | 20.7% | 19.5% | 18.6% | 17.5% | 13.8% | 15.3% | 14.7% |
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| Basic EPS [+] | $38.79 | $33.25 | $25.24 | $22.84 | $20.33 | $14.62 | $14.49 | $12.75 |
| Growth | 16.7% | 31.7% | 10.5% | 12.3% | 39.0% | 0.9% | 13.7% | 8.9% |
| Diluted EPS [+] | $38.41 | $32.78 | $24.91 | $22.47 | $19.88 | $14.24 | $14.22 | $12.48 |
| Growth | 17.2% | 31.6% | 10.9% | 13.0% | 39.6% | 0.2% | 14.0% | 9.1% |
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| Shares outstanding (basic) [+] | 22.5 | 23.1 | 23.9 | 24.6 | 25.2 | 25.7 | 26.5 | 27.7 |
| Growth | -2.8% | -3.2% | -2.8% | -2.6% | -1.9% | -3.0% | -4.2% | -4.2% |
| Shares outstanding (diluted) [+] | 22.7 | 23.5 | 24.2 | 25.0 | 25.8 | 26.4 | 27.0 | 28.3 |
| Growth | -3.2% | -3.1% | -3.1% | -3.1% | -2.3% | -2.3% | -4.4% | -4.4% |
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| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |
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