| In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 |
| | 10-K | 10-K | 10-K | 10-K | 10-K | S-1/A |
| Collaboration revenue | 70.8 | 19.8 | 44.9 | 17.0 | 3.4 | 14.1 |
| Collaboration revenue growth | 257.7% | -56.0% | 164.7% | 405.6% | -76.2% | |
| Operating expenses: | | | | | | |
| Research and development | 102.1 | 87.8 | 73.6 | 53.7 | 22.6 | |
| General and administrative | 32.1 | 27.8 | 18.5 | 10.2 | 5.4 | 2.8 |
| Total operating expenses | 134.2 | 115.6 | 92.1 | 64.0 | 28.0 | |
| (Loss) income from operations | -63.4 | -95.8 | -47.2 | -47.0 | -24.6 | -16.9 |
| Operating margin | -89.5% | -484.0% | -105.0% | -276.8% | -733.4% | |
| |
| Other income: | | | | | | |
| Interest income, net | 4.6 | 0.3 | 1.6 | 4.7 | 0.9 | 0.0 |
| Other income, net | -0.1 | 0.0 | 0.0 | -0.1 | 0.8 | |
| Total other income, net | 4.4 | 0.3 | 1.6 | 4.6 | 0.8 | 0.0 |
| (Loss) income before provision for income taxes | -59.0 | -95.5 | -45.6 | -42.4 | -23.8 | |
| Provision for income taxes | -0.1 | | 0.6 | -0.9 | | |
| Net (loss) income | -59.0 | -95.5 | -45.0 | -43.3 | -23.8 | -16.9 |
| |
| Net (loss) income per share, basic (in dollars per share) | ($1.55) | ($2.67) | ($1.47) | ($2.69) | ($22.28) | |
| Net (loss) income per share, diluted (in dollars per share) | ($1.55) | ($2.67) | ($1.47) | ($2.69) | ($22.28) | ($16,920.00) |
| |
| Weighted average common shares outstanding, basic (in shares) | 38.1 | 35.8 | 30.6 | 16.1 | 1.1 | |
| Weighted average common shares outstanding, diluted (in shares) | 38.1 | 35.8 | 30.6 | 16.1 | | |
| |
| Comprehensive (loss) income: | | | | | | |
| Net (loss) income | -59.0 | -95.5 | -45.0 | -43.3 | -23.8 | -16.9 |
| |
| Other comprehensive (loss) income: | | | | | | |
| |
| Total other comprehensive (loss) income | | | | | | |
| Comprehensive (loss) income | -61.9 | -96.0 | -45.1 | -43.3 | -23.8 | -16.9 |