| In millions, except per share items | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 | Dec-31-14 |
| | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
| Revenues [+] | 0.8 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.3 | 2.9 |
| Licensing | | | | | | | 0.2 | 2.0 |
| Royalties | | | | | | | | 11.0 |
| Contracts | | | | | | | 0.1 | 0.9 |
| Revenue growth | 250.4% | | | | | -100.0% | -89.1% | -32.7% |
| Cost of goods sold | 0.8 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 |
| Gross profit | 0.0 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.3 | 2.8 |
| Gross margin | -1.4% | 23.7% | | | | | 100.0% | 96.5% |
| Selling, general and administrative [+] | 10.5 | 11.2 | 11.8 | 9.4 | 8.2 | 8.2 | 6.3 | 4.4 |
| General and administrative | 10.5 | 11.2 | 11.8 | 9.4 | 8.2 | 8.2 | 6.3 | 4.4 |
| Research and development | 21.0 | 21.6 | 25.4 | 25.5 | 20.1 | 20.5 | 20.4 | 11.0 |
| Equity in earnings | | | | | | | | |
| EBITDA [+] | -29.8 | -31.3 | -36.5 | -34.1 | -25.7 | -26.1 | -23.9 | -9.6 |
| EBITDA growth | -5.0% | -14.2% | 7.1% | 32.4% | -1.3% | 9.1% | 149.9% | 33.4% |
| EBITDA margin | -3793.8% | -13987.5% | | | | | -7640.9% | -334.5% |
| Depreciation and amortization | 1.8 | 1.4 | 0.7 | 0.8 | 2.6 | 2.5 | 2.5 | 3.0 |
| EBIT [+] | -31.5 | -32.8 | -37.2 | -34.9 | -28.3 | -28.6 | -26.4 | -12.6 |
| EBIT growth | -3.7% | -11.9% | 6.7% | 23.2% | -1.2% | 8.6% | 109.1% | 65.9% |
| EBIT margin | -4016.8% | -14624.1% | | | | | -8424.3% | -440.8% |
| Non-recurring items [+] | | | | 0.5 | 0.1 | | | |
| Asset impairment | | | | 0.5 | 0.1 | | | |
| Interest expense, net [+] | 0.2 | 0.7 | 0.3 | 0.0 | 0.7 | 1.2 | 1.6 | |
| Interest expense | 0.2 | 0.7 | 0.5 | 0.4 | 0.8 | 1.2 | 1.6 | |
| Interest income | 0.0 | 0.0 | 0.2 | 0.4 | 0.1 | | | |
| Other income (expense), net [+] | 1.8 | 0.1 | -0.1 | 0.0 | 0.0 | 0.0 | -0.5 | -1.6 |
| Gain (loss) on debt retirement | | | | | | | -0.4 | |
| Change in fair value of warrants | | | | | | | 0.0 | -0.2 |
| Other | 1.8 | 0.1 | -0.1 | 0.0 | 0.0 | 0.0 | -0.1 | -0.1 |
| Pre-tax income | -29.9 | -33.4 | -37.6 | -35.4 | -29.1 | -29.8 | -28.4 | -14.2 |
| Income taxes | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| Tax rate | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Net income | -29.9 | -33.4 | -37.6 | -35.4 | -29.1 | -29.8 | -28.4 | -14.2 |
| Net margin | -3812.1% | -14896.9% | | | | | -9082.1% | -497.8% |
| |
| Basic EPS [+] | ($0.27) | ($0.49) | ($2.29) | ($3.74) | ($16.82) | ($43.36) | ($2.49) | ($2.78) |
| Growth | -45.7% | -78.6% | -38.7% | -77.8% | -61.2% | 1641.0% | -10.3% | 152.9% |
| Diluted EPS [+] | ($0.27) | ($0.49) | ($2.29) | ($3.74) | ($16.82) | ($43.36) | ($2.49) | ($2.78) |
| Growth | -45.7% | -78.6% | -38.7% | -77.8% | -61.2% | 1641.0% | -10.3% | 152.9% |
| |
| Shares outstanding (basic) [+] | 112.1 | 67.9 | 16.4 | 9.5 | 1.7 | 0.7 | 11.4 | 5.1 |
| Growth | 65.0% | 314.5% | 73.3% | 446.3% | 151.5% | -94.0% | 122.6% | 0.4% |
| Shares outstanding (diluted) [+] | 112.1 | 67.9 | 16.4 | 9.5 | 1.7 | 0.7 | 11.4 | 5.1 |
| Growth | 65.0% | 314.5% | 73.3% | 446.3% | 151.5% | -94.0% | 122.6% | 0.4% |
| |
| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |