The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X Genomics Inc Class A CL A COM 88025U109   134,354,315 2,408,215 SH   DFND 1 2,408,215 0 0
10X Genomics Inc Class A CL A COM 88025U109   133,142,947 2,386,502 SH   SOLE 0 2,158,586 0 227,916
10X Genomics Inc Class A CL A COM 88025U109   77,495,211 1,389,052 SH   DFND 3 1,136,982 0 252,070
10X Genomics Inc Class A CL A COM 88025U109   143,392,462 2,570,218 SH   DFND 2 2,255,751 0 314,467
2seventy bio COM 901384107   2,917 286 SH   DFND 3 286 0 0
8x8 Inc COM 282914100   8,528 2,045 SH   DFND 3 2,045 0 0
908 Devices COM 65443P102   2,141 249 SH   DFND 3 249 0 0
A. O. Smith COM 831865209   19,984 289 SH   DFND 3 289 0 0
ACM Research COM 00108J109   7,722 660 SH   DFND 3 660 0 0
AJ Gallagher & Co COM 363576109   305,542,349 1,597,106 SH   DFND 2 1,423,214 0 173,892
AJ Gallagher & Co COM 363576109   128,318,313 670,735 SH   DFND 1 670,735 0 0
AJ Gallagher & Co COM 363576109   82,276,118 430,067 SH   DFND 3 252,949 0 177,118
AJ Gallagher & Co COM 363576109   354,049,382 1,850,658 SH   SOLE 0 1,221,674 0 628,984
Abcam Plc ADR ADS 000380204   45,901,642 3,410,226 SH   DFND 1 3,410,226 0 0
Abcam Plc ADR ADS 000380204   25,547,551 1,898,035 SH   DFND 2 935,374 0 962,661
Abcam Plc ADR ADS 000380204   88,997,924 6,612,030 SH   SOLE 0 3,807,375 0 2,804,655
Abcellera Biologics Inc COM 00288U106   67,292,570 8,924,744 SH   DFND 2 5,912,839 0 3,011,905
Abcellera Biologics Inc COM 00288U106   35,715,314 4,736,779 SH   DFND 1 4,736,779 0 0
Abcellera Biologics Inc COM 00288U106   31,164,253 4,133,190 SH   DFND 3 3,339,353 0 793,837
Abcellera Biologics Inc COM 00288U106   15,342,264 2,034,783 SH   SOLE 0 1,260,789 0 773,994
Abcellera Biologics Inc COM 00288U106   1,169 155 SH   DFND 4 155 0 0
Acadia Pharmaceuticals Inc COM 004225108   11,631 618 SH   DFND 3 618 0 0
Accelerate Diagnostics COM 00430H102   293 418 SH   DFND 3 418 0 0
Accenture 'A' COM G1151C101   13,719 48 SH   DFND 3 48 0 0
Acutus Medical COM 005111109   320 424 SH   DFND 3 424 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107   6,601,655 6,056,564 SH   DFND 1 6,056,564 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107   3,706,679 3,400,623 SH   DFND 2 1,001,605 0 2,399,018
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107   6,935,528 6,362,870 SH   SOLE 0 6,362,870 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107   1,408,220 1,291,945 SH   DFND 3 1,291,945 0 0
Adeia Inc COM 00676P107   12,829 1,448 SH   DFND 3 1,448 0 0
Adicet Bio Inc COM 007002108   538,266 93,449 SH   DFND 1 93,449 0 0
Adicet Bio Inc COM 007002108   507,900 88,177 SH   SOLE 0 88,177 0 0
Adobe Systems COM 00724F101   28,993,312 75,235 SH   DFND 3 41,223 0 34,012
Adobe Systems COM 00724F101   108,133,666 280,597 SH   DFND 2 247,528 0 33,069
Adobe Systems COM 00724F101   37,262,581 96,693 SH   DFND 1 96,693 0 0
Adobe Systems COM 00724F101   137,982,885 358,053 SH   SOLE 0 235,185 0 122,868
Advanced Drainage Systems COM 00790R104   29,835,182 354,295 SH   DFND 1 354,295 0 0
Advanced Drainage Systems COM 00790R104   79,270,073 941,338 SH   DFND 2 766,858 0 174,480
Advanced Drainage Systems COM 00790R104   20,521,219 243,691 SH   DFND 3 137,964 0 105,727
Advanced Drainage Systems COM 00790R104   86,479,628 1,026,952 SH   SOLE 0 671,199 0 355,753
Advanced Micro Devices Inc COM 007903107   100,543,166 1,025,846 SH   DFND 3 880,449 0 145,397
Advanced Micro Devices Inc COM 007903107   527,134,142 5,378,371 SH   DFND 2 2,223,302 0 3,155,069
Advanced Micro Devices Inc COM 007903107   60,857,251 620,929 SH   DFND 1 620,929 0 0
Advanced Micro Devices Inc COM 007903107   166,925,143 1,703,144 SH   SOLE 0 734,783 0 968,361
Aerovironment COM 008073108   19,534,304 213,117 SH   DFND 1 213,117 0 0
Aerovironment COM 008073108   21,080,333 229,984 SH   DFND 2 66,864 0 163,120
Aerovironment COM 008073108   8,485,150 92,572 SH   DFND 3 92,572 0 0
Aerovironment COM 008073108   20,217,171 220,567 SH   SOLE 0 220,567 0 0
Affirm Holdings Inc Class A COM CL A 00827B106   35,512,660 3,151,079 SH   DFND 1 3,151,079 0 0
Affirm Holdings Inc Class A COM CL A 00827B106   107,786,257 9,563,998 SH   DFND 2 6,170,236 0 3,393,762
Affirm Holdings Inc Class A COM CL A 00827B106   69,159,358 6,136,589 SH   SOLE 0 5,108,252 0 1,028,337
Affirm Holdings Inc Class A COM CL A 00827B106   12,780,101 1,133,993 SH   DFND 3 976,404 0 157,589
Agios Pharmaceuticals Inc COM 00847X104   4,272 186 SH   DFND 3 186 0 0
Agnico Eagle Mines COM 008474108   1,913,822 37,548 SH   DFND 1 37,548 0 0
Agora Inc ADR ADS 00851L103   1,771,223 489,288 SH   DFND 1 489,288 0 0
Agora Inc ADR ADS 00851L103   923,143 255,012 SH   SOLE 0 255,012 0 0
Akili Inc COM 00974B107   1,946,080 1,216,300 SH   DFND 1 1,216,300 0 0
Akili Inc COM 00974B107   5,519,192 3,449,495 SH   SOLE 0 3,449,495 0 0
Albemarle Corp COM 012653101   99,097,316 448,323 SH   DFND 1 448,323 0 0
Albemarle Corp COM 012653101   183,634,285 830,774 SH   DFND 2 734,579 0 96,195
Albemarle Corp COM 012653101   54,763,986 247,756 SH   DFND 3 153,372 0 94,384
Albemarle Corp COM 012653101   224,080,184 1,013,754 SH   SOLE 0 698,569 0 315,185
Alector Inc COM 014442107   448,447 72,447 SH   DFND 1 72,447 0 0
Alector Inc COM 014442107   1,081,114 174,655 SH   DFND 3 174,655 0 0
Alector Inc COM 014442107   885,238 143,011 SH   DFND 2 143,011 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102   3,985 39 SH   DFND 4 39 0 0
Allbirds Inc COM CL A 01675A109   639,000 532,500 SH   SOLE 0 532,500 0 0
Alnylam Pharmaceuticals COM 02043Q107   460,722,378 2,299,932 SH   DFND 1 2,299,932 0 0
Alnylam Pharmaceuticals COM 02043Q107   636,389,597 3,176,865 SH   DFND 2 2,566,146 0 610,719
Alnylam Pharmaceuticals COM 02043Q107   393,449,714 1,964,106 SH   SOLE 0 1,386,035 0 578,071
Alnylam Pharmaceuticals COM 02043Q107   240,031,036 1,198,238 SH   DFND 3 932,360 0 265,878
Alphabet Inc Class A CAP STK CL A 02079K305   12,092,843 116,580 SH   DFND 1 116,580 0 0
Alphabet Inc Class A CAP STK CL A 02079K305   29,041,703 279,974 SH   DFND 2 243,890 0 36,084
Alphabet Inc Class A CAP STK CL A 02079K305   3,804,816 36,680 SH   DFND 3 23,936 0 12,744
Alphabet Inc Class A CAP STK CL A 02079K305   72,152,721 695,582 SH   SOLE 0 695,582 0 0
Alphabet Inc Class C CAP STK CL C 02079K107   104,719,784 1,006,921 SH   DFND 1 1,006,921 0 0
Alphabet Inc Class C CAP STK CL C 02079K107   335,676,016 3,227,654 SH   DFND 2 2,878,395 0 349,259
Alphabet Inc Class C CAP STK CL C 02079K107   309,519,496 2,976,149 SH   SOLE 0 1,698,564 0 1,277,585
Alphabet Inc Class C CAP STK CL C 02079K107   82,545,528 793,707 SH   DFND 3 434,969 0 358,738
Alteryx Inc COM 02156B103   22,536 383 SH   DFND 3 383 0 0
Amazon.Com COM 023135106   519,945,747 5,033,844 SH   DFND 1 5,033,844 0 0
Amazon.Com COM 023135106   1,908,881,316 18,480,795 SH   DFND 2 11,476,565 0 7,004,230
Amazon.Com COM 023135106   335,175,430 3,244,994 SH   DFND 3 2,559,828 0 685,166
Amazon.Com COM 023135106   1,227,323,283 11,882,305 SH   SOLE 0 8,544,125 0 3,338,180
Ambarella SHS G037AX101   21,685,342 280,100 SH   DFND 1 280,100 0 0
Ambarella SHS G037AX101   14,411,888 186,152 SH   DFND 2 54,075 0 132,077
Ambarella SHS G037AX101   6,014,295 77,684 SH   DFND 3 77,684 0 0
Ambarella SHS G037AX101   7,556,579 97,605 SH   SOLE 0 97,605 0 0
Amdocs COM G02602103   41,485 432 SH   DFND 3 432 0 0
Ameren COM 023608102   1,019,575 11,802 SH   DFND 1 11,802 0 0
American Superconductor Corp COM 030111207   3,551,747 723,370 SH   DFND 1 723,370 0 0
American Superconductor Corp COM 030111207   3,770,880 768,000 SH   SOLE 0 768,000 0 0
American Tower Corp REIT COM 03027X100   13,519,134 66,160 SH   DFND 1 66,160 0 0
American Tower Corp REIT COM 03027X100   1,317,789 6,449 SH   DFND 3 6,449 0 0
American Well Corp Class A COM 03044L105   16,152 6,844 SH   DFND 2 6,844 0 0
American Well Corp Class A COM 03044L105   228,974 97,023 SH   DFND 3 97,023 0 0
Amicus Therapeutics Inc COM 03152W109   5,966 538 SH   DFND 3 538 0 0
Amkor Technology COM 031652100   53,159 2,043 SH   DFND 3 2,043 0 0
Analog Devices COM 032654105   126,513,080 641,482 SH   DFND 1 641,482 0 0
Analog Devices COM 032654105   219,171,967 1,111,307 SH   DFND 2 989,195 0 122,112
Analog Devices COM 032654105   66,542,620 337,403 SH   DFND 3 214,898 0 122,505
Analog Devices COM 032654105   283,185,634 1,435,887 SH   SOLE 0 999,643 0 436,244
Anterix COM 03676C100   5,352 162 SH   DFND 3 162 0 0
Apellis Pharmaceuticals COM 03753U106   21,437 325 SH   DFND 3 325 0 0
Appian Corp CL A 03782L101   19,100,398 430,383 SH   DFND 2 124,063 0 306,320
Appian Corp CL A 03782L101   7,218,185 162,645 SH   DFND 3 162,645 0 0
Appian Corp CL A 03782L101   27,474,637 619,077 SH   DFND 1 619,077 0 0
Appian Corp CL A 03782L101   12,836,338 289,237 SH   SOLE 0 289,237 0 0
Apple COM 037833100   58,714,624 356,062 SH   DFND 1 356,062 0 0
Apple COM 037833100   515,313 3,125 SH   DFND 2 0 0 3,125
Apple COM 037833100   12,704,391 77,043 SH   DFND 3 77,043 0 0
Apple COM 037833100   33,846,549 205,255 SH   SOLE 0 205,255 0 0
Archer-Daniels-Midland Co COM 039483102   12,594,087 158,098 SH   DFND 2 158,098 0 0
Archer-Daniels-Midland Co COM 039483102   16,968 213 SH   DFND 3 213 0 0
Archer-Daniels-Midland Co COM 039483102   4,585,947 57,569 SH   SOLE 0 57,569 0 0
Ares Capital Corp COM 04010L103   20,667,709 1,130,928 SH   DFND 1 1,130,928 0 0
Ares Capital Corp COM 04010L103   3,422,524 187,279 SH   DFND 3 187,279 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101   1,786,285 16,660 SH   DFND 1 16,660 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101   3,686,224 34,380 SH   DFND 2 34,380 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101   4,358,815 40,653 SH   DFND 3 40,653 0 0
Asensus Surgical Inc COM 04367G103   3,499 5,338 SH   DFND 3 5,338 0 0
AstraZeneca ADR COM 046353108   31,651 456 SH   DFND 3 456 0 0
Atlassian Corp Plc CL A 049468101   248,632,983 1,452,550 SH   SOLE 0 629,339 0 823,211
Atlassian Corp Plc CL A 049468101   151,508,216 885,133 SH   DFND 3 761,190 0 123,943
Atlassian Corp Plc CL A 049468101   788,808,873 4,608,336 SH   DFND 2 1,905,527 0 2,702,809
Atlassian Corp Plc CL A 049468101   90,758,956 530,227 SH   DFND 1 530,227 0 0
Aurora Innovation Class A Common COM CL A 051774107   20,753,341 14,930,461 SH   SOLE 0 14,930,461 0 0
AutoZone COM 053332102   31,956 13 SH   DFND 3 13 0 0
AutoZone COM 053332102   6,354,318 2,585 SH   DFND 2 2,585 0 0
AutoZone COM 053332102   7,760,380 3,157 SH   SOLE 0 3,157 0 0
Autodesk COM 052769106   68,392,841 328,559 SH   DFND 1 328,559 0 0
Autodesk COM 052769106   42,400,319 203,691 SH   DFND 2 124,792 0 78,899
Autodesk COM 052769106   67,273,149 323,180 SH   DFND 3 253,508 0 69,672
Autodesk COM 052769106   20,193,185 97,008 SH   SOLE 0 29,794 0 67,214
Avery Dennison Corporation COM 053611109   23,619 132 SH   DFND 3 132 0 0
Axon Enterprise Inc COM 05464C101   95,074,450 422,835 SH   DFND 1 422,835 0 0
Axon Enterprise Inc COM 05464C101   183,639,717 816,721 SH   DFND 2 597,848 0 218,873
Axon Enterprise Inc COM 05464C101   56,701,549 252,175 SH   DFND 3 176,670 0 75,505
Axon Enterprise Inc COM 05464C101   196,204,560 872,602 SH   SOLE 0 606,737 0 265,865
Axonics Modulation Technologies COM 05465P101   10,803 198 SH   DFND 3 198 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108   402,583,779 2,667,531 SH   DFND 2 2,545,239 0 122,292
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303   120,369,277 45,942,472 SH   DFND 2 27,290,173 0 18,652,299
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303   14,298,820 5,457,565 SH   DFND 1 5,457,565 0 0
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303   11,205,114 4,276,761 SH   DFND 3 1,443,451 0 2,833,310
Bandwidth COM 05988J103   12,054 793 SH   DFND 2 793 0 0
Bandwidth COM 05988J103   174,238 11,463 SH   DFND 3 11,463 0 0
Beam Therapeutics COM 07373V105   3,827,776 125,009 SH   DFND 1 125,009 0 0
Beam Therapeutics COM 07373V105   4,551,510 148,645 SH   DFND 2 42,486 0 106,159
Beam Therapeutics COM 07373V105   1,601,487 52,302 SH   DFND 3 52,302 0 0
Beam Therapeutics COM 07373V105   3,882,769 126,805 SH   SOLE 0 126,805 0 0
BeiGene Ltd SPONSORED ADR 07725L102   51,167,253 237,402 SH   DFND 1 237,402 0 0
BeiGene Ltd SPONSORED ADR 07725L102   142,424,164 660,809 SH   SOLE 0 281,566 0 379,243
BeiGene Ltd SPONSORED ADR 07725L102   81,849,888 379,761 SH   DFND 3 323,842 0 55,919
BeiGene Ltd SPONSORED ADR 07725L102   439,549,727 2,039,390 SH   DFND 2 837,132 0 1,202,258
Beyond Meat Inc COM 08862E109   72,077 4,441 SH   DFND 1 4,441 0 0
Beyond Meat Inc COM 08862E109   3,879 239 SH   DFND 3 239 0 0
BioCryst Pharmaceuticals COM 09058V103   14,070 1,687 SH   DFND 3 1,687 0 0
BioNTech ADR SPONS ADS 09075V102   59,048,921 474,022 SH   DFND 1 474,022 0 0
BioNTech ADR SPONS ADS 09075V102   3,114 25 SH   DFND 4 25 0 0
BioNTech ADR SPONS ADS 09075V102   96,504,628 774,702 SH   DFND 3 690,083 0 84,619
BioNTech ADR SPONS ADS 09075V102   622,006,910 4,993,232 SH   DFND 2 2,371,479 0 2,621,753
BioNTech ADR SPONS ADS 09075V102   161,807,835 1,298,931 SH   SOLE 0 562,263 0 736,668
Blackline COM 09239B109   9,746,688 145,148 SH   DFND 3 145,148 0 0
Blackline COM 09239B109   24,605,774 366,430 SH   DFND 2 106,717 0 259,713
Blackline COM 09239B109   15,749,227 234,538 SH   DFND 1 234,538 0 0
Blackline COM 09239B109   17,725,787 263,973 SH   SOLE 0 263,973 0 0
Blackrock Inc COM 09247X101   17,397 26 SH   DFND 3 26 0 0
Blink Charging COM 09354A100   3,425 396 SH   DFND 3 396 0 0
Block Inc COM 852234103   8,208,206 119,566 SH   DFND 2 119,566 0 0
Block Inc COM 852234103   14,417 210 SH   DFND 3 210 0 0
Block Inc COM 852234103   3,992,753 58,161 SH   SOLE 0 58,161 0 0
Bluebird Bio Inc COM 09609G100   2,735 860 SH   DFND 3 860 0 0
Blueprint Medicines Corp COM 09627Y109   14,172 315 SH   DFND 3 315 0 0
Booking Holdings Inc COM 09857L108   57,310,623 21,607 SH   DFND 1 21,607 0 0
Booking Holdings Inc COM 09857L108   176,310,998 66,472 SH   DFND 2 58,987 0 7,485
Booking Holdings Inc COM 09857L108   45,393,345 17,114 SH   DFND 3 9,400 0 7,714
Booking Holdings Inc COM 09857L108   210,646,445 79,417 SH   SOLE 0 52,015 0 27,402
Boston Omaha COM 101044105   16,001 676 SH   DFND 3 676 0 0
Box Inc COM 10316T104   28,049 1,047 SH   DFND 3 1,047 0 0
Bristol Myers Squibb COM 110122108   36,804 531 SH   DFND 3 531 0 0
Broadridge Finl.Sltn. COM 11133T103   55,406,538 378,021 SH   DFND 1 378,021 0 0
Broadridge Finl.Sltn. COM 11133T103   172,403,549 1,176,254 SH   DFND 2 1,046,900 0 129,354
Broadridge Finl.Sltn. COM 11133T103   43,759,646 298,558 SH   DFND 3 164,725 0 133,833
Broadridge Finl.Sltn. COM 11133T103   192,029,272 1,310,154 SH   SOLE 0 837,724 0 472,430
Brookfield Renewable COM 11284V105   28,031,053 802,033 SH   DFND 1 802,033 0 0
Brookfield Renewable COM 11284V105   3,249,511 92,976 SH   DFND 3 92,976 0 0
Brunswick Corp COM 117043109   19,926 243 SH   DFND 3 243 0 0
Bumble Inc COM CL A 12047B105   7,055,478 360,894 SH   SOLE 0 360,894 0 0
Burford Capital ORD SHS G17977110   10,101,038 1,082,755 SH   DFND 1 1,082,755 0 0
Burford Capital ORD SHS G17977110   6,640,452 711,807 SH   DFND 2 625,973 0 85,834
Burning Rock Biotech Ltd ADR SPON ADS 12233L107   450,109 160,181 SH   DFND 1 160,181 0 0
C3.ai CL A 12468P104   3,928 117 SH   DFND 3 117 0 0
CEVA Inc COM 157210105   3,526,228 115,880 SH   DFND 1 115,880 0 0
CEVA Inc COM 157210105   2,510,475 82,500 SH   SOLE 0 82,500 0 0
CEVA Inc COM 157210105   1,908,691 62,724 SH   DFND 3 62,724 0 0
CEVA Inc COM 157210105   4,224,445 138,825 SH   DFND 2 41,393 0 97,432
CIA Cervecerias Unidas ADR SPONSORED ADR 204429104   5,593,977 357,900 SH   DFND 3 0 0 357,900
CRH Plc ADR ADR 12626K203   10,734 211 SH   DFND 4 211 0 0
CS Disco Inc COM 126327105   228,403 34,398 SH   DFND 3 34,398 0 0
CS Disco Inc COM 126327105   16,095 2,424 SH   DFND 2 2,424 0 0
Calix Inc COM 13100M509   524,860 9,794 SH   DFND 3 9,794 0 0
Calix Inc COM 13100M509   37,406 698 SH   DFND 2 698 0 0
Canadian Pacific Railway COM 13645T100   111,178,996 1,445,797 SH   DFND 2 1,219,940 0 225,857
Cardlytics Inc COM 14161W105   1,337,372 393,924 SH   DFND 1 393,924 0 0
Cardlytics Inc COM 14161W105   898,059 264,524 SH   SOLE 0 264,524 0 0
Cardlytics Inc COM 14161W105   763,189 224,798 SH   DFND 3 224,798 0 0
Cardlytics Inc COM 14161W105   1,845,845 543,695 SH   DFND 2 160,589 0 383,106
Cargurus Inc COM 141788109   39,490 2,114 SH   DFND 2 2,114 0 0
Cargurus Inc COM 141788109   559,373 29,945 SH   DFND 3 29,945 0 0
Carmax Inc COM 143130102   6,196,335 96,396 SH   DFND 2 96,396 0 0
Carmax Inc COM 143130102   17,227 268 SH   DFND 3 268 0 0
Carmax Inc COM 143130102   4,703,560 73,173 SH   SOLE 0 73,173 0 0
Carvana COM 146869102   31,595,815 3,227,356 SH   SOLE 0 2,043,968 0 1,183,388
Carvana COM 146869102   78,367,912 8,004,894 SH   DFND 2 4,008,839 0 3,996,055
Carvana COM 146869102   16,388,812 1,674,036 SH   DFND 1 1,674,036 0 0
Carvana COM 146869102   11,275,946 1,151,782 SH   DFND 3 969,267 0 182,515
Castle Biosciences COM 14843C105   5,112 225 SH   DFND 3 225 0 0
Cbre Group Inc CL A 12504L109   44,944,594 617,286 SH   DFND 1 617,286 0 0
Cbre Group Inc CL A 12504L109   159,863,529 2,195,626 SH   SOLE 0 1,431,429 0 764,197
Cbre Group Inc CL A 12504L109   35,928,677 493,458 SH   DFND 3 273,771 0 219,687
Cbre Group Inc CL A 12504L109   154,557,719 2,122,754 SH   DFND 2 1,905,127 0 217,627
Cellectis ADR SPONS ADS 15117K103   1,290,911 668,866 SH   DFND 2 464,958 0 203,908
Cellectis ADR SPONS ADS 15117K103   964,160 499,565 SH   DFND 1 499,565 0 0
Cellectis ADR SPONS ADS 15117K103   180,509 93,528 SH   DFND 3 76,659 0 16,869
Cellectis ADR SPONS ADS 15117K103   729,418 377,937 SH   SOLE 0 377,937 0 0
Celsius Holdings COM 15118V207   28,997 312 SH   DFND 3 312 0 0
Cemex ADR SPON ADR NEW 151290889   248,625,681 44,959,436 SH   DFND 2 11,795,100 0 33,164,336
Cemex ADR SPON ADR NEW 151290889   63,234,167 11,434,750 SH   DFND 1 11,434,750 0 0
Cemex ADR SPON ADR NEW 151290889   97,343,152 17,602,740 SH   DFND 3 1,732,114 0 15,870,626
Cemex ADR SPON ADR NEW 151290889   4,361,953 788,780 SH   SOLE 0 788,780 0 0
Cemex ADR SPON ADR NEW 151290889   4,384,831 792,917 SH   DFND 4 792,917 0 0
Certara COM 15687V109   27,627,818 1,145,907 SH   DFND 1 1,145,907 0 0
Certara COM 15687V109   80,674,013 3,346,081 SH   DFND 2 2,952,572 0 393,509
Certara COM 15687V109   98,470,834 4,084,232 SH   SOLE 0 2,632,508 0 1,451,724
Certara COM 15687V109   22,244,513 922,626 SH   DFND 3 509,337 0 413,289
Cerus COM 157085101   4,333 1,459 SH   DFND 3 1,459 0 0
ChargePoint Holdings Inc COM CL A 15961R105   60,183,036 5,748,141 SH   SOLE 0 5,748,141 0 0
ChargePoint Holdings Inc COM CL A 15961R105   80,818 7,719 SH   DFND 1 7,719 0 0
Charles River Laboratories International COM 159864107   30,273 150 SH   DFND 3 150 0 0
Charles River Laboratories International COM 159864107   11,717,467 58,059 SH   DFND 2 58,059 0 0
Charles River Laboratories International COM 159864107   5,505,851 27,281 SH   SOLE 0 27,281 0 0
Charles Schwab COM 808513105   47,783,760 912,252 SH   DFND 1 912,252 0 0
Charles Schwab COM 808513105   143,624,546 2,741,973 SH   DFND 2 2,426,674 0 315,299
Charles Schwab COM 808513105   37,370,144 713,443 SH   DFND 3 392,239 0 321,204
Charles Schwab COM 808513105   169,458,467 3,235,175 SH   SOLE 0 2,114,813 0 1,120,362
Chegg COM 163092109   82,863,740 5,083,665 SH   DFND 1 5,083,665 0 0
Chegg COM 163092109   99,620,400 6,111,681 SH   DFND 2 5,304,914 0 806,767
Chegg COM 163092109   25,416,427 1,559,290 SH   SOLE 0 1,559,290 0 0
Chegg COM 163092109   11,491,924 705,026 SH   DFND 3 645,802 0 59,224
Chewy Inc CL A 16679L109   146,158,043 3,910,060 SH   DFND 1 3,910,060 0 0
Chewy Inc CL A 16679L109   278,619,867 7,453,715 SH   DFND 2 7,068,764 0 384,951
Chewy Inc CL A 16679L109   36,052,150 964,477 SH   DFND 3 622,569 0 341,908
Chewy Inc CL A 16679L109   157,011,924 4,200,426 SH   SOLE 0 2,929,751 0 1,270,675
Chinook Therapeutics COM 16961L106   2,136,166 92,275 SH   DFND 1 92,275 0 0
Chinook Therapeutics COM 16961L106   4,724,475 204,081 SH   DFND 2 60,146 0 143,935
Chinook Therapeutics COM 16961L106   2,709,893 117,058 SH   SOLE 0 117,058 0 0
Chinook Therapeutics COM 16961L106   1,694,140 73,181 SH   DFND 3 73,181 0 0
Church & Dwight Co Inc COM 171340102   19,892 225 SH   DFND 3 225 0 0
Cisco Systems COM 17275R102   30,010,084 574,081 SH   DFND 1 574,081 0 0
Cisco Systems COM 17275R102   17,597,542 336,634 SH   SOLE 0 336,634 0 0
Cisco Systems COM 17275R102   6,374,152 121,935 SH   DFND 3 121,935 0 0
Cisco Systems COM 17275R102   280,351 5,363 SH   DFND 2 0 0 5,363
Clear Secure Inc COM 18467V109   26,170,000 1,000,000 SH   SOLE 0 1,000,000 0 0
Cloudflare Inc CL A COM 18915M107   398,495,200 6,462,783 SH   SOLE 0 4,435,317 0 2,027,466
Cloudflare Inc CL A COM 18915M107   123,932,037 2,009,926 SH   DFND 3 1,628,423 0 381,503
Cloudflare Inc CL A COM 18915M107   238,818,552 3,873,152 SH   DFND 1 3,873,152 0 0
Cloudflare Inc CL A COM 18915M107   824,509,628 13,371,872 SH   DFND 2 8,387,118 0 4,984,754
CoStar Group COM 22160N109   218,201,967 3,169,237 SH   DFND 1 3,169,237 0 0
CoStar Group COM 22160N109   401,843,369 5,836,505 SH   DFND 2 5,596,802 0 239,703
CoStar Group COM 22160N109   43,087,363 625,815 SH   DFND 3 416,866 0 208,949
CoStar Group COM 22160N109   186,543,429 2,709,418 SH   SOLE 0 1,968,812 0 740,606
Coca Cola COM 191216100   18,861,400 304,069 SH   DFND 1 304,069 0 0
Coca Cola COM 191216100   462,868 7,462 SH   DFND 2 0 0 7,462
Coca Cola COM 191216100   955,200 15,399 SH   DFND 3 15,399 0 0
Coca Cola COM 191216100   29,147,029 469,886 SH   SOLE 0 469,886 0 0
Codexis COM 192005106   8,719,896 2,106,255 SH   DFND 1 2,106,255 0 0
Codexis COM 192005106   6,644,563 1,604,967 SH   SOLE 0 1,604,967 0 0
Codexis COM 192005106   2,791,648 674,311 SH   DFND 3 674,311 0 0
Codexis COM 192005106   7,128,608 1,721,886 SH   DFND 2 495,066 0 1,226,820
Cognex Corp COM 192422103   29,294,208 591,205 SH   DFND 1 591,205 0 0
Cognex Corp COM 192422103   13,018,470 262,734 SH   SOLE 0 262,734 0 0
Cognex Corp COM 192422103   6,864,607 138,539 SH   DFND 3 122,639 0 15,900
Cognex Corp COM 192422103   4,004,730 80,822 SH   DFND 2 29,829 0 50,993
Cognizant Technology Solutions Corp CL A 192446102   13,039 214 SH   DFND 3 214 0 0
Cognyte Software ORD SHS M25133105   1,251 369 SH   DFND 3 369 0 0
Coherent Corp COM 19247G107   19,649 516 SH   DFND 3 516 0 0
Coherus BioSciences COM 19249H103   10,841 1,585 SH   DFND 3 1,585 0 0
Cohu COM 192576106   30,251 788 SH   DFND 3 788 0 0
Coinbase Global Inc COM CL A 19260Q107   862,734 12,768 SH   SOLE 0 12,768 0 0
Coinbase Global Inc COM CL A 19260Q107   3,176 47 SH   DFND 3 47 0 0
Consensus Cloud Solutions COM 20848V105   818 24 SH   DFND 3 24 0 0
Consolidated Edison COM 209115104   866,101 9,053 SH   DFND 3 9,053 0 0
Consolidated Edison COM 209115104   11,135,127 116,391 SH   DFND 1 116,391 0 0
Cooper Cos Inc/The COM 216648402   11,167,198 29,910 SH   DFND 2 29,910 0 0
Copa Holdings S A CL A P31076105   64,481,263 698,227 SH   DFND 3 74,166 0 624,061
Copa Holdings S A CL A P31076105   3,050,598 33,033 SH   DFND 4 33,033 0 0
Copa Holdings S A CL A P31076105   28,652,049 310,255 SH   DFND 1 310,255 0 0
Copa Holdings S A CL A P31076105   275,319,269 2,981,259 SH   DFND 2 1,977,298 0 1,003,961
Corning COM 219350105   25,790 731 SH   DFND 3 731 0 0
Costco Wholesale Corporation COM 22160K105   38,756 78 SH   DFND 3 78 0 0
Coupang CL A 22266T109   1,083,904 67,744 SH   DFND 4 67,744 0 0
Coupang CL A 22266T109   258,221,552 16,138,847 SH   SOLE 0 8,580,431 0 7,558,416
Coupang CL A 22266T109   141,190,000 8,824,375 SH   DFND 3 5,727,980 0 3,096,395
Coupang CL A 22266T109   1,265,597,600 79,099,850 SH   DFND 2 52,126,552 0 26,973,298
Coupang CL A 22266T109   127,113,536 7,944,596 SH   DFND 1 7,944,596 0 0
Coursera Inc COM 22266M104   22,839,875 1,982,628 SH   SOLE 0 1,454,291 0 528,337
Coursera Inc COM 22266M104   32,416,980 2,813,974 SH   DFND 3 2,268,903 0 545,071
Coursera Inc COM 22266M104   86,889,600 7,542,500 SH   DFND 2 6,864,384 0 678,116
Coursera Inc COM 22266M104   73,767,249 6,403,407 SH   DFND 1 6,403,407 0 0
Credicorp COM G2519Y108   37,560,764 283,713 SH   DFND 3 32,802 0 250,911
Credicorp COM G2519Y108   1,908,799 14,418 SH   DFND 4 14,418 0 0
Credicorp COM G2519Y108   124,798,757 942,660 SH   DFND 2 417,061 0 525,599
Credicorp COM G2519Y108   20,562,285 155,316 SH   DFND 1 155,316 0 0
Crispr Therapeutics AG REG SHS H17182108   3,373,615 74,588 SH   SOLE 0 74,588 0 0
Crispr Therapeutics AG REG SHS H17182108   581,748 12,862 SH   DFND 3 8,803 0 4,059
Crispr Therapeutics AG REG SHS H17182108   401,642 8,880 SH   DFND 2 8,880 0 0
Crispr Therapeutics AG REG SHS H17182108   7,554,360 167,021 SH   DFND 1 167,021 0 0
CrowdStrike Holdings COM 22788C105   15,648 114 SH   DFND 3 114 0 0
CyberArk Software Ltd SHS M2682V108   8,525,424 57,612 SH   SOLE 0 57,612 0 0
CyberArk Software Ltd SHS M2682V108   6,461,547 43,665 SH   DFND 3 43,665 0 0
CyberArk Software Ltd SHS M2682V108   15,386,960 103,980 SH   DFND 2 30,224 0 73,756
CyberArk Software Ltd SHS M2682V108   5,996,594 40,523 SH   DFND 1 40,523 0 0
Cytokinetics Inc COM NEW 23282W605   11,965 340 SH   DFND 3 340 0 0
Dada Nexus Ltd ADR ADS 23344D108   27,889,271 3,292,712 SH   DFND 2 3,292,712 0 0
Dada Nexus Ltd ADR ADS 23344D108   311,840 36,817 SH   DFND 3 36,817 0 0
Dada Nexus Ltd ADR ADS 23344D108   20,012,213 2,362,717 SH   DFND 1 2,362,717 0 0
Dada Nexus Ltd ADR ADS 23344D108   11,916,392 1,406,894 SH   SOLE 0 1,406,894 0 0
Datadog COM 23804L103   111,099,174 1,529,028 SH   DFND 1 1,529,028 0 0
Datadog COM 23804L103   206,647,002 2,844,027 SH   DFND 2 2,717,410 0 126,617
Datadog COM 23804L103   24,459,245 336,626 SH   DFND 3 220,007 0 116,619
Datadog COM 23804L103   100,642,892 1,385,121 SH   SOLE 0 985,110 0 400,011
Deere & Co COM 244199105   111,168,766 269,252 SH   DFND 2 178,643 0 90,609
Deere & Co COM 244199105   154,865,508 375,086 SH   DFND 1 375,086 0 0
Deere & Co COM 244199105   156,144,610 378,184 SH   DFND 3 299,097 0 79,087
Deere & Co COM 244199105   50,439,485 122,165 SH   SOLE 0 48,378 0 73,787
Denali Therapeutics COM 24823R105   71,034,209 3,083,082 SH   DFND 1 3,083,082 0 0
Denali Therapeutics COM 24823R105   107,037,827 4,645,739 SH   DFND 2 4,505,448 0 140,291
Denali Therapeutics COM 24823R105   9,921,738 430,631 SH   DFND 3 397,365 0 33,266
Denali Therapeutics COM 24823R105   165,718,863 7,192,659 SH   SOLE 0 7,192,659 0 0
DermTech COM 24984K105   1,052 286 SH   DFND 3 286 0 0
Dexcom Inc COM 252131107   257,056,034 2,212,567 SH   DFND 1 2,212,567 0 0
Dexcom Inc COM 252131107   1,042,993,983 8,977,397 SH   DFND 2 3,918,712 0 5,058,685
Dexcom Inc COM 252131107   345,987,874 2,978,033 SH   DFND 3 2,494,469 0 483,564
Dexcom Inc COM 252131107   347,320,342 2,989,502 SH   SOLE 0 1,279,053 0 1,710,449
Digimarc COM 25381B101   2,333,241 118,740 SH   DFND 3 118,740 0 0
Digimarc COM 25381B101   5,514,301 280,626 SH   DFND 2 85,774 0 194,852
Digimarc COM 25381B101   5,157,044 262,445 SH   DFND 1 262,445 0 0
Digimarc COM 25381B101   3,040,071 154,711 SH   SOLE 0 154,711 0 0
Digital Realty Trust REIT COM 253868103   450,456 4,582 SH   DFND 1 4,582 0 0
Docebo COM 25609L105   8,256,720 203,094 SH   DFND 2 178,313 0 24,781
Docebo COM 25609L105   10,855 267 SH   DFND 3 267 0 0
Dolby Laboratories 'A' COM 25659T107   22,179,986 259,658 SH   DFND 1 259,658 0 0
Dolby Laboratories 'A' COM 25659T107   10,237,587 119,850 SH   DFND 2 117,505 0 2,345
Dolby Laboratories 'A' COM 25659T107   21,562,400 252,428 SH   SOLE 0 252,428 0 0
Dolby Laboratories 'A' COM 25659T107   4,565,528 53,448 SH   DFND 3 53,448 0 0
Dollar General Corp COM 256677105   15,153 72 SH   DFND 3 72 0 0
Domo COM 257554105   4,555 321 SH   DFND 3 321 0 0
Donaldson COM 257651109   31,886 488 SH   DFND 3 488 0 0
Doordash Inc COM 25809K105   146,373,595 2,302,920 SH   DFND 1 2,302,920 0 0
Doordash Inc COM 25809K105   265,603,320 4,178,781 SH   DFND 2 4,013,816 0 164,965
Doordash Inc COM 25809K105   178,054,823 2,801,366 SH   SOLE 0 2,307,553 0 493,813
Doordash Inc COM 25809K105   28,191,212 443,537 SH   DFND 3 299,058 0 144,479
Doximity Inc CLASS A 26622P107   48,065,746 1,484,427 SH   DFND 1 1,484,427 0 0
Doximity Inc CLASS A 26622P107   62,446,546 1,928,553 SH   DFND 2 1,911,910 0 16,643
Doximity Inc CLASS A 26622P107   10,158,869 313,739 SH   DFND 3 313,739 0 0
Doximity Inc CLASS A 26622P107   21,435,754 662,006 SH   SOLE 0 662,006 0 0
DraftKings Inc COM CL A 26142V105   27,685 1,430 SH   DFND 3 1,430 0 0
Dropbox CL A 26210C104   21,815 1,009 SH   DFND 3 1,009 0 0
Duolingo Inc CL A COM 26603R106   224,529,344 1,574,650 SH   DFND 1 1,574,650 0 0
Duolingo Inc CL A COM 26603R106   82,900,685 581,392 SH   DFND 3 472,611 0 108,781
Duolingo Inc CL A COM 26603R106   276,094,593 1,936,283 SH   DFND 2 1,797,112 0 139,171
Duolingo Inc CL A COM 26603R106   53,513,884 375,299 SH   SOLE 0 270,030 0 105,269
EHang Holdings Ltd ADR ADS 26853E102   36,222 3,314 SH   DFND 1 3,314 0 0
Eargo Inc COM 270087109   61 13 SH   DFND 3 13 0 0
Eaton COM G29183103   120,432,659 702,887 SH   DFND 2 619,536 0 83,351
Eaton COM G29183103   40,996,864 239,272 SH   DFND 1 239,272 0 0
Eaton COM G29183103   32,677,451 190,717 SH   DFND 3 105,065 0 85,652
Eaton COM G29183103   145,253,656 847,751 SH   SOLE 0 543,021 0 304,730
Ecolab COM 278865100   69,126,983 417,610 SH   DFND 1 417,610 0 0
Ecolab COM 278865100   50,871,673 307,326 SH   DFND 2 207,043 0 100,283
Ecolab COM 278865100   67,215,608 406,063 SH   DFND 3 317,738 0 88,325
Ecolab COM 278865100   19,774,048 119,459 SH   SOLE 0 33,860 0 85,599
Edwards Lifesciences Corp COM 28176E108   9,395,977 113,574 SH   DFND 3 113,574 0 0
Edwards Lifesciences Corp COM 28176E108   19,701,901 238,147 SH   DFND 2 238,147 0 0
Edwards Lifesciences Corp COM 28176E108   3,796,314 45,888 SH   DFND 1 45,888 0 0
Edwards Lifesciences Corp COM 28176E108   5,780,759 69,875 SH   SOLE 0 69,875 0 0
Elastic ORD SHS N14506104   442,015,143 7,634,113 SH   DFND 2 6,652,597 0 981,516
Electronic Arts, Inc. COM 285512109   24,933 207 SH   DFND 3 207 0 0
Elevance Health Inc COM 036752103   174,131,426 378,703 SH   DFND 1 378,703 0 0
Elevance Health Inc COM 036752103   536,692,531 1,167,205 SH   DFND 2 1,035,363 0 131,842
Elevance Health Inc COM 036752103   138,240,497 300,647 SH   DFND 3 165,681 0 134,966
Elevance Health Inc COM 036752103   621,413,903 1,351,458 SH   SOLE 0 870,338 0 481,120
Enanta Pharmaceuticals COM 29251M106   14,558 360 SH   DFND 3 360 0 0
Enphase Energy Inc COM 29355A107   201,448 958 SH   DFND 1 958 0 0
Enphase Energy Inc COM 29355A107   21,659 103 SH   DFND 3 103 0 0
Entegris Inc COM 29362U104   26,817,844 327,007 SH   DFND 1 327,007 0 0
Entegris Inc COM 29362U104   76,793,836 936,396 SH   DFND 2 826,215 0 110,181
Entegris Inc COM 29362U104   20,613,624 251,355 SH   DFND 3 135,982 0 115,373
Entegris Inc COM 29362U104   93,748,337 1,143,133 SH   SOLE 0 728,186 0 414,947
Estee Lauder 'A' COM 518439104   66,247,709 268,797 SH   DFND 1 268,797 0 0
Estee Lauder 'A' COM 518439104   219,715,886 891,487 SH   DFND 2 797,257 0 94,230
Estee Lauder 'A' COM 518439104   247,186,564 1,002,948 SH   SOLE 0 656,802 0 346,146
Estee Lauder 'A' COM 518439104   53,177,935 215,767 SH   DFND 3 118,792 0 96,975
EverQuote Inc COM CL A 30041R108   2,073,616 149,181 SH   DFND 3 149,181 0 0
EverQuote Inc COM CL A 30041R108   3,596,500 258,741 SH   DFND 2 77,422 0 181,319
EverQuote Inc COM CL A 30041R108   9,993,641 718,967 SH   DFND 1 718,967 0 0
EverQuote Inc COM CL A 30041R108   3,218,545 231,550 SH   SOLE 0 231,550 0 0
Everbridge Inc COM 29978A104   6,956,848 200,659 SH   DFND 1 200,659 0 0
Everbridge Inc COM 29978A104   5,146,623 148,446 SH   SOLE 0 148,446 0 0
Everbridge Inc COM 29978A104   6,796,256 196,027 SH   DFND 2 57,778 0 138,249
Everbridge Inc COM 29978A104   2,893,905 83,470 SH   DFND 3 83,470 0 0
Eversource Energy COM 30040W108   11,244,397 143,680 SH   DFND 1 143,680 0 0
Eversource Energy COM 30040W108   657,932 8,407 SH   DFND 3 8,407 0 0
Exact Sciences COM 30063P105   42,240,205 622,920 SH   DFND 3 509,014 0 113,906
Exact Sciences COM 30063P105   103,865,526 1,531,714 SH   DFND 2 962,439 0 569,275
Exact Sciences COM 30063P105   73,348,178 1,081,672 SH   DFND 1 1,081,672 0 0
Exact Sciences COM 30063P105   104,836,972 1,546,040 SH   SOLE 0 1,160,982 0 385,058
Exelixis COM 30161Q104   27,077 1,395 SH   DFND 3 1,395 0 0
Exelon Corporation COM 30161N101   957,647 22,861 SH   DFND 1 22,861 0 0
Expedia Group Inc COM 30212P303   19,309 199 SH   DFND 3 199 0 0
Expeditors Intl COM 302130109   13,765 125 SH   DFND 3 125 0 0
Expensify Inc COM CL A 30219Q106   22,551 2,767 SH   DFND 2 2,767 0 0
Expensify Inc COM CL A 30219Q106   5,681,854 697,160 SH   DFND 1 697,160 0 0
Expensify Inc COM CL A 30219Q106   316,424 38,825 SH   DFND 3 38,825 0 0
Expensify Inc COM CL A 30219Q106   2,927,024 359,144 SH   SOLE 0 359,144 0 0
Exponent COM 30214U102   26,418 265 SH   DFND 3 265 0 0
Exscientia Ltd ADR ADS 30223G102   5,908,573 1,114,825 SH   DFND 1 1,114,825 0 0
Exscientia Ltd ADR ADS 30223G102   1,993,065 376,050 SH   DFND 3 376,050 0 0
Exscientia Ltd ADR ADS 30223G102   10,793,567 2,036,522 SH   DFND 2 389,701 0 1,646,821
Exscientia Ltd ADR ADS 30223G102   9,087,820 1,714,683 SH   SOLE 0 930,650 0 784,033
FTI Consulting COM 302941109   36,510 185 SH   DFND 3 185 0 0
FTI Consulting COM 302941109   10,092,084 51,138 SH   SOLE 0 51,138 0 0
Factset Research Systems COM 303075105   33,207 80 SH   DFND 3 80 0 0
Farfetch ORD SHS CL A 30744W107   25,379,662 5,168,974 SH   DFND 1 5,168,974 0 0
Farfetch ORD SHS CL A 30744W107   103,956,955 21,172,496 SH   DFND 2 15,501,723 0 5,670,773
Farfetch ORD SHS CL A 30744W107   13,441,449 2,737,566 SH   DFND 3 1,642,049 0 1,095,517
Farfetch ORD SHS CL A 30744W107   76,684,429 15,618,010 SH   SOLE 0 9,679,229 0 5,938,781
Fastenal COM 311900104   79,727,527 1,478,078 SH   DFND 1 1,478,078 0 0
Fastenal COM 311900104   49,012,149 908,642 SH   SOLE 0 908,642 0 0
Fastenal COM 311900104   17,971,729 333,180 SH   DFND 3 318,181 0 14,999
Fastenal COM 311900104   15,549,176 288,268 SH   DFND 2 229,031 0 59,237
Fastly CL A 31188V100   3,641 205 SH   DFND 3 205 0 0
Fate Therapeutics COM 31189P102   2,120 372 SH   DFND 3 372 0 0
Ferrari NV COM N3167Y103   368,325,761 1,359,921 SH   SOLE 0 1,359,921 0 0
Ferrari NV COM N3167Y103   1,624,781,193 5,998,779 SH   DFND 2 4,641,594 0 1,357,185
Fibrogen Inc COM 31572Q808   10,058 539 SH   DFND 3 539 0 0
First Industrial REIT COM 32054K103   21,644,739 406,856 SH   DFND 1 406,856 0 0
First Industrial REIT COM 32054K103   2,218,227 41,696 SH   DFND 3 41,696 0 0
Fiverr Intl ORD SHS M4R82T106   4,174,162 119,535 SH   DFND 3 119,535 0 0
Fiverr Intl ORD SHS M4R82T106   10,188,329 291,762 SH   DFND 2 86,109 0 205,653
Fiverr Intl ORD SHS M4R82T106   12,001,410 343,683 SH   DFND 1 343,683 0 0
Fiverr Intl ORD SHS M4R82T106   11,295,782 323,476 SH   SOLE 0 323,476 0 0
Floor & Decor Holdings CL A 339750101   24,043,176 244,789 SH   DFND 3 135,485 0 109,304
Floor & Decor Holdings CL A 339750101   88,820,150 904,298 SH   DFND 2 799,016 0 105,282
Floor & Decor Holdings CL A 339750101   30,010,532 305,544 SH   DFND 1 305,544 0 0
Floor & Decor Holdings CL A 339750101   110,990,073 1,130,015 SH   SOLE 0 739,969 0 390,046
Fortis COM 349553107   1,015,282 23,917 SH   DFND 1 23,917 0 0
Fortive Corp COM 34959J108   6,667,980 97,814 SH   DFND 2 97,814 0 0
Fox COM 35137L105   16,344 480 SH   DFND 3 480 0 0
Freshpet Inc COM 358039105   35,941 543 SH   DFND 2 543 0 0
Freshpet Inc COM 358039105   505,890 7,643 SH   DFND 3 7,643 0 0
Full Truck Alliance Co Ltd ADR SPONS ADS 35969L108   120,403,586 15,821,759 SH   DFND 2 15,396,396 0 425,363
Futu Hdgs ADR SPON ADR CL A 36118L106   56,049,176 1,080,987 SH   DFND 2 823,109 0 257,878
Futu Hdgs ADR SPON ADR CL A 36118L106   1,607 31 SH   DFND 4 31 0 0
GAN COM G3728V109   738 572 SH   DFND 3 572 0 0
Gentex Corp COM 371901109   16,341 583 SH   DFND 3 583 0 0
Ginkgo Bioworks Holdings Inc CL A COM 37611X100   29,056,525 21,847,011 SH   DFND 1 21,847,011 0 0
Ginkgo Bioworks Holdings Inc CL A COM 37611X100   115,432,655 86,791,470 SH   DFND 2 48,395,045 0 38,396,425
Ginkgo Bioworks Holdings Inc CL A COM 37611X100   17,531,473 13,181,559 SH   DFND 3 11,422,564 0 1,758,995
Ginkgo Bioworks Holdings Inc CL A COM 37611X100   160,994,133 121,048,220 SH   SOLE 0 109,728,005 0 11,320,215
GitLab CLASS A 37637K108   14,127 412 SH   DFND 3 412 0 0
GitLab CLASS A 37637K108   3,874,496 112,992 SH   SOLE 0 112,992 0 0
Globus Medical CL A 379577208   22,939 405 SH   DFND 3 405 0 0
Globus Medical CL A 379577208   6,212,898 109,691 SH   SOLE 0 109,691 0 0
Golub Capital BDC Inc COM 38173M102   1,655,676 122,100 SH   DFND 1 122,100 0 0
Goodyear Tire & Rubber Co/The COM 382550101   18,800 1,706 SH   DFND 3 1,706 0 0
Graco COM 384109104   29,277 401 SH   DFND 3 401 0 0
Grainger, WW COM 384802104   46,839 68 SH   DFND 3 68 0 0
HDFC Bank ADR ADR REPS 3 SHS 40415F101   97,325,866 1,459,815 SH   DFND 2 1,265,571 0 194,244
HDFC Bank ADR ADR REPS 3 SHS 40415F101   11,433,505 171,494 SH   DFND 3 113,811 0 57,683
HDFC Bank ADR ADR REPS 3 SHS 40415F101   117,984,366 1,769,677 SH   SOLE 0 1,082,203 0 687,474
HUYA ADR ADS REP SHS A 44852D108   4,131,898 1,144,570 SH   DFND 1 1,144,570 0 0
HUYA ADR ADS REP SHS A 44852D108   2,242,319 621,141 SH   SOLE 0 621,141 0 0
Harris Corp COM 502431109   11,971 61 SH   DFND 3 61 0 0
Hashicorp Inc COM CL A 418100103   77,268,660 2,638,056 SH   DFND 1 2,638,056 0 0
Hashicorp Inc COM CL A 418100103   110,800,438 3,782,876 SH   DFND 2 3,515,608 0 267,268
Hashicorp Inc COM CL A 418100103   8,263,588 282,130 SH   DFND 3 282,130 0 0
Hashicorp Inc COM CL A 418100103   16,916,820 577,563 SH   SOLE 0 577,563 0 0
Health Catalyst Inc COM 42225T107   2,783,867 238,549 SH   DFND 2 238,549 0 0
Health Catalyst Inc COM 42225T107   3,023,043 259,044 SH   DFND 3 259,044 0 0
Health Catalyst Inc COM 42225T107   1,215,664 104,170 SH   DFND 1 104,170 0 0
Healthcare Realty Trust REIT CL A COM 42226K105   298,977 15,467 SH   DFND 1 15,467 0 0
Healthcare Services Group Inc COM 421906108   2,178 157 SH   DFND 3 157 0 0
Heron Therapeutics Inc COM 427746102   465 308 SH   DFND 3 308 0 0
Hershey Foods Corporation COM 427866108   6,879,755 27,042 SH   SOLE 0 27,042 0 0
Hershey Foods Corporation COM 427866108   25,187 99 SH   DFND 3 99 0 0
Hershey Foods Corporation COM 427866108   19,291,910 75,830 SH   DFND 2 75,830 0 0
Hillenbrand COM 431571108   8,080 170 SH   DFND 3 170 0 0
Howard Hughes COM 44267D107   26,120,480 326,506 SH   DFND 1 326,506 0 0
Howard Hughes COM 44267D107   74,783,440 934,793 SH   DFND 2 827,351 0 107,442
Howard Hughes COM 44267D107   20,245,280 253,066 SH   DFND 3 142,291 0 110,775
Howard Hughes COM 44267D107   89,645,440 1,120,568 SH   SOLE 0 708,054 0 412,514
Humana COM 444859102   31,069 64 SH   DFND 3 64 0 0
Hutchison China Meditech SPONSORED ADR 44842L103   1,981,970 152,225 SH   DFND 3 0 0 152,225
ICICI Bank ADR ADR 45104G104   58,129,636 2,693,681 SH   DFND 1 2,693,681 0 0
ICICI Bank ADR ADR 45104G104   58,787,826 2,724,181 SH   DFND 2 2,724,181 0 0
ICICI Bank ADR ADR 45104G104   10,549,491 488,855 SH   DFND 3 329,682 0 159,173
ICICI Bank ADR ADR 45104G104   2,397,689 111,107 SH   DFND 4 111,107 0 0
IPG Photonics Corp COM 44980X109   11,139,332 90,336 SH   SOLE 0 90,336 0 0
IPG Photonics Corp COM 44980X109   5,562,267 45,108 SH   DFND 3 45,108 0 0
IPG Photonics Corp COM 44980X109   14,889,313 120,747 SH   DFND 1 120,747 0 0
IPG Photonics Corp COM 44980X109   13,425,623 108,877 SH   DFND 2 31,590 0 77,287
Illumina COM 452327109   2,029,342,226 8,726,477 SH   DFND 2 6,453,547 0 2,272,930
Illumina COM 452327109   306,052,078 1,316,070 SH   DFND 3 1,053,085 0 262,985
Illumina COM 452327109   358,722,328 1,542,560 SH   DFND 1 1,542,560 0 0
Illumina COM 452327109   811,192,770 3,488,251 SH   SOLE 0 2,588,351 0 899,900
InMode SHS M5425M103   21,062 659 SH   DFND 3 659 0 0
Incyte Corp COM 45337C102   11,925 165 SH   DFND 3 165 0 0
Infinera COM 45667G103   24,832 3,200 SH   DFND 3 3,200 0 0
Infosys Ltd ADR SPONSORED ADR 456788108   2,978,543 170,788 SH   DFND 4 170,788 0 0
Infosys Ltd ADR SPONSORED ADR 456788108   14,919,920 855,500 SH   DFND 2 114,422 0 741,078
Infosys Ltd ADR SPONSORED ADR 456788108   16,307,917 935,087 SH   DFND 1 935,087 0 0
Infosys Ltd ADR SPONSORED ADR 456788108   20,561,673 1,178,995 SH   DFND 3 470,491 0 708,504
Insmed Inc COM 457669307   13,674 802 SH   DFND 3 802 0 0
Inspire Medical Systems COM 457730109   43,303 185 SH   DFND 3 185 0 0
Intercept Pharmaceuticals Inc COM 45845P108   1,356 101 SH   DFND 3 101 0 0
International Game Technology SHS G4863A108   34,063 1,271 SH   DFND 3 1,271 0 0
Intuit COM 461202103   32,319,554 72,493 SH   DFND 1 72,493 0 0
Intuit COM 461202103   300,935 675 SH   DFND 2 0 0 675
Intuit COM 461202103   6,801,582 15,256 SH   DFND 3 15,256 0 0
Intuit COM 461202103   19,141,265 42,934 SH   SOLE 0 42,934 0 0
Intuitive Surgical COM NEW 46120E602   658,504,837 2,577,621 SH   DFND 2 1,064,009 0 1,513,612
Intuitive Surgical COM NEW 46120E602   75,527,662 295,642 SH   DFND 1 295,642 0 0
Intuitive Surgical COM NEW 46120E602   125,704,780 492,053 SH   DFND 3 423,220 0 68,833
Intuitive Surgical COM NEW 46120E602   207,931,887 813,919 SH   SOLE 0 352,096 0 461,823
Invitae COM 46185L103   1,080 800 SH   DFND 3 800 0 0
Ionis Pharmaceuticals COM 462222100   2,124,135 59,433 SH   DFND 1 59,433 0 0
Ionis Pharmaceuticals COM 462222100   4,521,825 126,520 SH   DFND 2 126,520 0 0
Ionis Pharmaceuticals COM 462222100   5,243,272 146,706 SH   DFND 3 146,706 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106   9,919,645 2,036,888 SH   DFND 1 2,036,888 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106   33,293,531 6,836,454 SH   DFND 2 453,282 0 6,383,172
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106   30,337,675 6,229,502 SH   DFND 3 747,989 0 5,481,513
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106   1,828,446 375,451 SH   DFND 4 375,451 0 0
J&J Snack Foods Corp COM 466032109   15,267 103 SH   DFND 3 103 0 0
JFrog Ltd ORD SHS M6191J100   11,917,298 604,939 SH   DFND 1 604,939 0 0
JFrog Ltd ORD SHS M6191J100   9,866,784 500,852 SH   DFND 2 145,045 0 355,807
JFrog Ltd ORD SHS M6191J100   4,098,368 208,039 SH   DFND 3 208,039 0 0
JFrog Ltd ORD SHS M6191J100   8,157,396 414,081 SH   SOLE 0 414,081 0 0
Jack Henry & Associates COM 426281101   9,345 62 SH   DFND 3 62 0 0
Jazz Pharmaceuticals SHS G50871105   28,242 193 SH   DFND 3 193 0 0
Joby Aviation Inc COM G65163100   38,817 8,944 SH   DFND 1 8,944 0 0
Joby Aviation Inc COM G65163100   33,319,048 7,677,200 SH   SOLE 0 7,677,200 0 0
Johnson & Johnson COM 478160104   16,740 108 SH   DFND 3 108 0 0
Jumia Technologies Ag ADR SPONSORED ADS 48138M105   30,825,767 9,369,534 SH   DFND 2 8,697,830 0 671,704
Jumia Technologies Ag ADR SPONSORED ADS 48138M105   1,230 374 SH   DFND 3 374 0 0
KE Holdings ADR ADR 482497104   8,228,238 436,743 SH   DFND 1 436,743 0 0
KE Holdings ADR ADR 482497104   19,991,124 1,061,100 SH   DFND 2 628,601 0 432,499
KE Holdings ADR ADR 482497104   1,081,284 57,393 SH   DFND 3 8,210 0 49,183
KE Holdings ADR ADR 482497104   911,969 48,406 SH   SOLE 0 48,406 0 0
KFORCE INC. COM 493732101   21,185 335 SH   DFND 3 335 0 0
Knowles Corp COM 49926D109   22,644 1,332 SH   DFND 3 1,332 0 0
Kulicke & Soffa Industries Inc COM 501242101   28,295 537 SH   DFND 3 537 0 0
Lemonade Inc COM 52567D107   35,717,764 2,504,752 SH   DFND 2 2,480,142 0 24,610
Lemonade Inc COM 52567D107   21,294,130 1,493,277 SH   DFND 1 1,493,277 0 0
Lemonade Inc COM 52567D107   1,386,557 97,234 SH   DFND 3 97,234 0 0
Lemonade Inc COM 52567D107   13,521,646 948,222 SH   SOLE 0 948,222 0 0
LendingTree COM 52603B107   4,952,761 185,775 SH   DFND 2 54,367 0 131,408
LendingTree COM 52603B107   4,937,272 185,194 SH   DFND 1 185,194 0 0
LendingTree COM 52603B107   1,945,327 72,968 SH   DFND 3 72,968 0 0
LendingTree COM 52603B107   3,124,739 117,207 SH   SOLE 0 117,207 0 0
Liberty Broadband Corp COM 530307305   9,232 113 SH   DFND 3 113 0 0
Lightspeed POS COM 53229C107   4,707 310 SH   DFND 3 310 0 0
Lilium N.V. CL A COM N52586109   9,983 15,359 SH   DFND 1 15,359 0 0
Lilium N.V. CL A COM N52586109   727,300 1,118,923 SH   DFND 2 1,118,923 0 0
Lilium N.V. CL A COM N52586109   9,863,327 15,174,349 SH   SOLE 0 15,174,349 0 0
Lincoln Electric Holdings Inc COM 533900106   17,417 103 SH   DFND 3 103 0 0
LivePerson Inc COM 538146101   1,296,941 294,091 SH   DFND 1 294,091 0 0
LivePerson Inc COM 538146101   1,093,151 247,880 SH   SOLE 0 247,880 0 0
LivePerson Inc COM 538146101   546,540 123,932 SH   DFND 3 123,932 0 0
LivePerson Inc COM 538146101   1,586,224 359,688 SH   DFND 2 104,853 0 254,835
Liveramp Holdings Inc COM 53815P108   13,495,744 615,401 SH   DFND 1 615,401 0 0
Liveramp Holdings Inc COM 53815P108   8,393,664 382,748 SH   DFND 2 114,541 0 268,207
Liveramp Holdings Inc COM 53815P108   3,749,219 170,963 SH   DFND 3 170,963 0 0
Liveramp Holdings Inc COM 53815P108   6,470,995 295,075 SH   SOLE 0 295,075 0 0
Logitech International SA SHS H50430232   13,659 235 SH   DFND 3 235 0 0
Lufax Holding Ltd COM 54975P102   11,456,754 5,616,056 SH   DFND 1 5,616,056 0 0
Lufax Holding Ltd COM 54975P102   2,085,335 1,022,223 SH   DFND 3 144,625 0 877,598
Lufax Holding Ltd COM 54975P102   37,758,289 18,508,965 SH   DFND 2 12,209,188 0 6,299,777
Lyell Immunopharma Inc COM 55083R104   779,978 330,499 SH   DFND 3 330,499 0 0
Lyell Immunopharma Inc COM 55083R104   311,973 132,192 SH   DFND 1 132,192 0 0
Lyell Immunopharma Inc COM 55083R104   704,767 298,630 SH   DFND 2 298,630 0 0
Lyft Inc Class A Common CL A COM 55087P104   4,524 488 SH   DFND 3 488 0 0
MELI Kaszek Pioneer CL A COM G5S74L106   20,400,000 2,000,000 SH   DFND 2 2,000,000 0 0
MP Materials COM CL A 553368101   38,568,881 1,368,176 SH   DFND 1 1,368,176 0 0
MP Materials COM CL A 553368101   2,886,656 102,400 SH   DFND 3 102,400 0 0
MakeMyTrip SHS V5633W109   55,924,668 2,285,438 SH   DFND 2 1,687,249 0 598,189
Marathon Digital Holdings COM 565788106   1,744 200 SH   DFND 3 200 0 0
Markel Corp COM 570535104   46,016,140 36,023 SH   DFND 1 36,023 0 0
Markel Corp COM 570535104   146,255,781 114,494 SH   DFND 2 101,454 0 13,040
Markel Corp COM 570535104   175,337,297 137,260 SH   SOLE 0 90,576 0 46,684
Markel Corp COM 570535104   37,884,148 29,657 SH   DFND 3 16,491 0 13,166
MarketAxess Holdings COM 57060D108   179,423,290 458,543 SH   DFND 1 458,543 0 0
MarketAxess Holdings COM 57060D108   270,982,411 692,536 SH   DFND 2 556,183 0 136,353
MarketAxess Holdings COM 57060D108   73,193,142 187,056 SH   SOLE 0 187,056 0 0
MarketAxess Holdings COM 57060D108   36,055,808 92,146 SH   DFND 3 85,160 0 6,986
Marriott International CL A 571903202   20,423 123 SH   DFND 3 123 0 0
Martin Marietta Materials COM 573284106   139,148,014 391,900 SH   DFND 1 391,900 0 0
Martin Marietta Materials COM 573284106   351,735,573 990,637 SH   SOLE 0 712,568 0 278,069
Martin Marietta Materials COM 573284106   96,880,606 272,857 SH   DFND 3 152,675 0 120,182
Martin Marietta Materials COM 573284106   437,440,311 1,232,018 SH   DFND 2 1,089,450 0 142,568
Masimo Corp COM 574795100   6,731,650 36,478 SH   DFND 2 36,478 0 0
Masimo Corp COM 574795100   3,166,153 17,157 SH   DFND 1 17,157 0 0
Masimo Corp COM 574795100   7,820,252 42,377 SH   DFND 3 42,377 0 0
Mastercard Inc-Class A CL A 57636Q104   327,558,513 901,347 SH   DFND 2 794,455 0 106,892
Mastercard Inc-Class A CL A 57636Q104   113,789,486 313,116 SH   DFND 1 313,116 0 0
Mastercard Inc-Class A CL A 57636Q104   85,660,461 235,713 SH   DFND 3 130,721 0 104,992
Mastercard Inc-Class A CL A 57636Q104   381,962,807 1,051,052 SH   SOLE 0 674,764 0 376,288
Materialise Nv ADR SPONSORED ADS 57667T100   2,224,400 268,000 SH   DFND 2 268,000 0 0
Mativ Inc COM 808541106   7,300 340 SH   DFND 3 340 0 0
MaxCyte COM 57777K106   1,414,459 293,325 SH   DFND 1 293,325 0 0
Maxlinear Inc COM 57776J100   16,197 460 SH   DFND 3 460 0 0
McDonald's COM 580135101   307,012 1,098 SH   DFND 2 0 0 1,098
McDonald's COM 580135101   13,209,615 47,243 SH   DFND 1 47,243 0 0
McDonald's COM 580135101   683,926 2,446 SH   DFND 3 2,446 0 0
McDonald's COM 580135101   20,520,578 73,390 SH   SOLE 0 73,390 0 0
Medifast Inc COM 58470H101   15,965 154 SH   DFND 3 154 0 0
Medtronic COM G5960L103   203,807 2,528 SH   DFND 2 0 0 2,528
Medtronic COM G5960L103   20,215,223 250,747 SH   DFND 1 250,747 0 0
Medtronic COM G5960L103   4,106,138 50,932 SH   DFND 3 50,932 0 0
Medtronic COM G5960L103   12,889,687 159,882 SH   SOLE 0 159,882 0 0
MercadoLibre COM 58733R102   536,102,452 406,736 SH   DFND 1 406,736 0 0
MercadoLibre COM 58733R102   6,041,530,991 4,583,654 SH   DFND 2 3,542,843 0 1,040,811
MercadoLibre COM 58733R102   423,185,570 321,067 SH   DFND 3 232,071 0 88,996
MercadoLibre COM 58733R102   11,076,976 8,404 SH   DFND 4 8,404 0 0
MercadoLibre COM 58733R102   1,064,718,323 807,792 SH   SOLE 0 689,328 0 118,464
Merck COM 58933Y105   15,746 148 SH   DFND 3 148 0 0
Meta Platforms Inc CL A 30303M102   58,729,422 277,104 SH   DFND 3 151,250 0 125,854
Meta Platforms Inc CL A 30303M102   226,513,842 1,068,764 SH   DFND 2 946,558 0 122,206
Meta Platforms Inc CL A 30303M102   74,975,471 353,758 SH   DFND 1 353,758 0 0
Meta Platforms Inc CL A 30303M102   264,319,275 1,247,142 SH   SOLE 0 799,084 0 448,058
Mettler-Toledo COM 592688105   5,404,702 3,532 SH   DFND 3 2,313 0 1,219
Mettler-Toledo COM 592688105   360,174,709 235,376 SH   DFND 2 173,236 0 62,140
Mettler-Toledo COM 592688105   84,189,094 55,018 SH   DFND 1 55,018 0 0
Mettler-Toledo COM 592688105   38,588,836 25,218 SH   SOLE 0 25,218 0 0
Microsoft COM 594918104   150,852,110 523,247 SH   DFND 3 314,000 0 209,247
Microsoft COM 594918104   545,235,843 1,891,210 SH   DFND 2 1,690,577 0 200,633
Microsoft COM 594918104   247,055,802 856,940 SH   DFND 1 856,940 0 0
Microsoft COM 594918104   676,711,887 2,347,249 SH   SOLE 0 1,576,963 0 770,286
Mirati Therapeutics COM 60468T105   7,957 214 SH   DFND 3 214 0 0
Mobileye Global Inc. ORD SHS 60741F104   267,241,361 6,176,135 SH   DFND 2 5,239,864 0 936,271
Moderna Inc COM 60770K107   698,924,918 4,550,885 SH   DFND 1 4,550,885 0 0
Moderna Inc COM 60770K107   3,854,994,225 25,100,887 SH   DFND 2 19,514,688 0 5,586,199
Moderna Inc COM 60770K107   466,622,421 3,038,302 SH   DFND 3 2,467,586 0 570,716
Moderna Inc COM 60770K107   2,115,732,977 13,776,097 SH   SOLE 0 11,755,775 0 2,020,322
Momentive Global Inc COM 60878Y108   12,479 1,339 SH   DFND 3 1,339 0 0
MongoDB Inc COM 60937P106   1,394,058 5,980 SH   SOLE 0 5,980 0 0
MongoDB Inc COM 60937P106   60,378 259 SH   DFND 3 259 0 0
Monolithic Power Systems Inc COM 609839105   33,036 66 SH   DFND 3 66 0 0
Moody's Corp COM 615369105   540,737,034 1,766,999 SH   SOLE 0 1,114,332 0 652,667
Moody's Corp COM 615369105   119,756,643 391,336 SH   DFND 3 213,677 0 177,659
Moody's Corp COM 615369105   149,039,697 487,026 SH   DFND 1 487,026 0 0
Moody's Corp COM 615369105   456,363,036 1,491,285 SH   DFND 2 1,322,412 0 168,873
NIO Inc ADR SPON ADS 62914V106   29,773,527 2,832,876 SH   DFND 1 2,832,876 0 0
NIO Inc ADR SPON ADS 62914V106   867,794,830 82,568,490 SH   DFND 2 62,592,124 0 19,976,366
NIO Inc ADR SPON ADS 62914V106   47,510,812 4,520,534 SH   DFND 3 3,861,656 0 658,878
NIO Inc ADR SPON ADS 62914V106   317,514,625 30,210,716 SH   SOLE 0 25,822,064 0 4,388,652
NVIDIA COM 67066G104   466,863,872 1,680,757 SH   DFND 1 1,680,757 0 0
NVIDIA COM 67066G104   2,632,287,127 9,476,499 SH   DFND 2 6,073,365 0 3,403,134
NVIDIA COM 67066G104   311,468,223 1,121,317 SH   DFND 3 968,557 0 152,760
NVIDIA COM 67066G104   1,036,889,855 3,732,908 SH   SOLE 0 2,770,898 0 962,010
Nano Dimension ADR SPONS ADS 63008G203   4,624 1,600 SH   DFND 3 1,600 0 0
Nanobiotix ADR COM 63009J107   3,088,553 850,841 SH   DFND 1 850,841 0 0
Nanobiotix ADR COM 63009J107   1,993,447 549,159 SH   SOLE 0 549,159 0 0
Nektar Therapeutics COM 640268108   967 1,376 SH   DFND 3 1,376 0 0
Netflix Inc COM 64110L106   322,948,485 934,782 SH   DFND 1 934,782 0 0
Netflix Inc COM 64110L106   1,184,305,440 3,428,000 SH   DFND 2 2,061,259 0 1,366,741
Netflix Inc COM 64110L106   190,406,120 551,135 SH   DFND 3 458,610 0 92,525
Netflix Inc COM 64110L106   613,123,701 1,774,701 SH   SOLE 0 1,267,183 0 507,518
New Relic COM 64829B100   59,856 795 SH   DFND 3 795 0 0
New York Times Co COM 650111107   4,227,384 108,729 SH   DFND 2 108,729 0 0
New York Times Co COM 650111107   15,163 390 SH   DFND 3 390 0 0
New York Times Co COM 650111107   4,277,966 110,030 SH   SOLE 0 110,030 0 0
Newmont Mining COM 651639106   1,855,309 37,848 SH   DFND 1 37,848 0 0
NextEra Energy COM 65339F101   3,639,178 47,213 SH   DFND 1 47,213 0 0
NextEra Energy COM 65339F101   331,675 4,303 SH   DFND 3 4,303 0 0
Nike COM 654106103   11,038 90 SH   DFND 3 90 0 0
Novanta Inc COM 67000B104   83,204 523 SH   DFND 2 523 0 0
Novanta Inc COM 67000B104   1,164,857 7,322 SH   DFND 3 7,322 0 0
Novavax Inc COM NEW 670002401   901 130 SH   DFND 3 130 0 0
Novocure Ltd ORD SHS G6674U108   142,090,613 2,362,664 SH   DFND 1 2,362,664 0 0
Novocure Ltd ORD SHS G6674U108   221,474,812 3,682,654 SH   DFND 2 3,211,953 0 470,701
Novocure Ltd ORD SHS G6674U108   115,849,727 1,926,334 SH   SOLE 0 1,462,571 0 463,763
Novocure Ltd ORD SHS G6674U108   37,999,399 631,849 SH   DFND 3 507,201 0 124,648
Nu Holdings Ltd. ORD SHS CL A G6683N103   62,263,470 13,080,561 SH   DFND 1 13,080,561 0 0
Nu Holdings Ltd. ORD SHS CL A G6683N103   415,111,251 87,208,246 SH   DFND 2 75,398,637 0 11,809,609
Nu Holdings Ltd. ORD SHS CL A G6683N103   101,339,286 21,289,766 SH   DFND 3 10,177,331 0 11,112,435
Nu Holdings Ltd. ORD SHS CL A G6683N103   18,514,339 3,889,567 SH   SOLE 0 1,201,697 0 2,687,870
Nucana Plc ADR SPONSORED ADR 67022C106   1,189,553 1,238,989 SH   SOLE 0 1,238,989 0 0
Nucana Plc ADR SPONSORED ADR 67022C106   2,323,481 2,420,041 SH   DFND 1 2,420,041 0 0
Nutanix Inc COM 67059N108   18,791 723 SH   DFND 3 723 0 0
Oatly Inc. SPONS ADS 67421J108   89,167,702 36,846,158 SH   DFND 2 30,631,807 0 6,214,351
On Semiconductor Corp COM 682189105   50,956 619 SH   DFND 3 619 0 0
OpenDoor Technologies COM 683712103   12,672 7,200 SH   SOLE 0 7,200 0 0
Opko Health Inc COM 68375N103   9,687 6,635 SH   DFND 3 6,635 0 0
Oscar Health Inc COM 687793109   335,600 51,315 SH   DFND 1 51,315 0 0
Oscar Health Inc COM 687793109   729,694 111,574 SH   DFND 2 111,574 0 0
Oscar Health Inc COM 687793109   5,376,456 822,088 SH   SOLE 0 822,088 0 0
Oscar Health Inc COM 687793109   786,893 120,320 SH   DFND 3 120,320 0 0
Outset Medical COM 690145107   7,102 386 SH   DFND 3 386 0 0
Ozon Holdings ADR COM 69269L104   0 2,307,811 SH   DFND 2 1,289,275 0 1,018,536
Ozon Holdings ADR COM 69269L104   0 333,970 SH   DFND 1 333,970 0 0
Ozon Holdings ADR COM 69269L104   0 19,278 SH   DFND 3 19,278 0 0
PDD Holdings Inc SPONSORED ADS 722304102   1,208,946,130 15,928,144 SH   DFND 2 8,663,052 0 7,265,092
PDD Holdings Inc SPONSORED ADS 722304102   109,683,014 1,445,099 SH   DFND 1 1,445,099 0 0
PDD Holdings Inc SPONSORED ADS 722304102   182,120,760 2,399,483 SH   DFND 3 2,081,017 0 318,466
PDD Holdings Inc SPONSORED ADS 722304102   638,965,516 8,418,518 SH   SOLE 0 6,291,211 0 2,127,307
PROCEPT BioRobotics COM 74276L105   12,354 435 SH   DFND 3 435 0 0
Pacira BioSciences COM 695127100   29,308,436 718,168 SH   DFND 1 718,168 0 0
Pacira BioSciences COM 695127100   12,651,386 310,007 SH   SOLE 0 310,007 0 0
Pacira BioSciences COM 695127100   23,998,933 588,065 SH   DFND 2 189,848 0 398,217
Pacira BioSciences COM 695127100   11,206,467 274,601 SH   DFND 3 235,428 0 39,173
PagerDuty COM 69553P100   19,764 565 SH   DFND 3 565 0 0
Paychex COM 704326107   15,699 137 SH   DFND 3 137 0 0
Peloton Interactive Inc CL A COM 70614W100   5,147,702 453,942 SH   DFND 2 284,216 0 169,726
Peloton Interactive Inc CL A COM 70614W100   7,767,764 684,988 SH   DFND 1 684,988 0 0
Peloton Interactive Inc CL A COM 70614W100   8,289,302 730,979 SH   DFND 3 568,266 0 162,713
Peloton Interactive Inc CL A COM 70614W100   2,475,669 218,313 SH   SOLE 0 64,753 0 153,560
Penumbra Inc COM 70975L107   108,745,395 390,202 SH   DFND 2 386,423 0 3,779
Penumbra Inc COM 70975L107   74,651,018 267,864 SH   DFND 1 267,864 0 0
Penumbra Inc COM 70975L107   4,689,238 16,826 SH   DFND 3 16,826 0 0
Penumbra Inc COM 70975L107   14,899,882 53,464 SH   SOLE 0 53,464 0 0
Pepsico COM 713448108   595,210 3,265 SH   DFND 2 0 0 3,265
Pepsico COM 713448108   66,053,853 362,336 SH   DFND 1 362,336 0 0
Pepsico COM 713448108   14,197,524 77,880 SH   DFND 3 77,880 0 0
Pepsico COM 713448108   38,907,560 213,426 SH   SOLE 0 213,426 0 0
Petrobras Common ADR SPONSORED ADR 71654V408   121,285,495 11,628,523 SH   DFND 1 11,628,523 0 0
Petrobras Common ADR SPONSORED ADR 71654V408   427,436,482 40,981,446 SH   DFND 2 21,974,375 0 19,007,071
Petrobras Common ADR SPONSORED ADR 71654V408   39,195,752 3,757,982 SH   DFND 3 1,577,943 0 2,180,039
Petrobras Common ADR SPONSORED ADR 71654V408   7,031,624 674,173 SH   DFND 4 674,173 0 0
Petrobras Common ADR SPONSORED ADR 71654V408   6,587,369 631,579 SH   SOLE 0 631,579 0 0
Petrobras Pref ADR SP ADR NON VTG 71654V101   12,108,795 1,304,827 SH   DFND 1 1,304,827 0 0
Petrobras Pref ADR SP ADR NON VTG 71654V101   74,169,064 7,992,356 SH   DFND 2 6,340,289 0 1,652,067
Petrobras Pref ADR SP ADR NON VTG 71654V101   6,709,728 723,031 SH   DFND 3 60,763 0 662,268
Pfizer COM 717081103   19,013 466 SH   DFND 3 466 0 0
PhenomeX Inc COM 084310101   521,749 449,784 SH   DFND 1 449,784 0 0
PhenomeX Inc COM 084310101   339,472 292,648 SH   DFND 2 292,648 0 0
PhenomeX Inc COM 084310101   414,902 357,674 SH   DFND 3 357,674 0 0
PhenomeX Inc COM 084310101   286,260 246,776 SH   SOLE 0 246,776 0 0
Physicians Realty Trust COM 71943U104   419,847 28,121 SH   DFND 1 28,121 0 0
Piedmont Lithium Inc COM 72016P105   15,073 251 SH   DFND 3 251 0 0
Pinterest COM 72352L106   86,025,260 3,154,575 SH   DFND 1 3,154,575 0 0
Pinterest COM 72352L106   129,887,228 4,763,008 SH   DFND 2 4,716,684 0 46,324
Pinterest COM 72352L106   5,492,423 201,409 SH   DFND 3 201,409 0 0
Pinterest COM 72352L106   18,175,755 666,511 SH   SOLE 0 666,511 0 0
Precision BioSciences Inc COM 74019P108   3,061 4,062 SH   DFND 2 4,062 0 0
Precision BioSciences Inc COM 74019P108   42,713 56,678 SH   DFND 3 56,678 0 0
Procter & Gamble COM 742718109   70,758,597 475,880 SH   DFND 1 475,880 0 0
Procter & Gamble COM 742718109   636,393 4,280 SH   DFND 2 0 0 4,280
Procter & Gamble COM 742718109   41,353,811 278,121 SH   SOLE 0 278,121 0 0
Procter & Gamble COM 742718109   15,271,206 102,705 SH   DFND 3 102,705 0 0
Progressive COM 743315103   28,898 202 SH   DFND 3 202 0 0
Progressive COM 743315103   9,525,793 66,586 SH   DFND 2 66,586 0 0
Progressive COM 743315103   7,841,262 54,811 SH   SOLE 0 54,811 0 0
Progyny COM 74340E103   17,696,257 550,942 SH   DFND 2 171,720 0 379,222
Progyny COM 74340E103   19,854,753 618,143 SH   DFND 1 618,143 0 0
Progyny COM 74340E103   7,710,053 240,039 SH   DFND 3 214,131 0 25,908
Progyny COM 74340E103   7,432,086 231,385 SH   SOLE 0 231,385 0 0
Prologis Inc REIT COM 74340W103   35,099,797 281,316 SH   DFND 1 281,316 0 0
Prologis Inc REIT COM 74340W103   3,474,969 27,851 SH   DFND 3 27,851 0 0
Proterra Inc COM 74374T109   18,857 12,406 SH   DFND 1 12,406 0 0
Ptc Therapeutics Inc COM 69366J200   13,466 278 SH   DFND 3 278 0 0
Pure Storage Inc COM 74624M102   37,755 1,480 SH   DFND 3 1,480 0 0
Q2 Holdings Inc COM 74736L109   3,360,852 136,509 SH   DFND 1 136,509 0 0
Q2 Holdings Inc COM 74736L109   4,394,104 178,477 SH   DFND 2 52,776 0 125,701
Q2 Holdings Inc COM 74736L109   1,972,234 80,107 SH   DFND 3 80,107 0 0
Q2 Holdings Inc COM 74736L109   3,009,426 122,235 SH   SOLE 0 122,235 0 0
Qualcomm COM 747525103   25,771 202 SH   DFND 3 202 0 0
Quanterix Corp COM 74766Q101   4,408,091 391,135 SH   DFND 1 391,135 0 0
Quanterix Corp COM 74766Q101   23,351 2,072 SH   DFND 2 2,072 0 0
Quanterix Corp COM 74766Q101   2,363,060 209,677 SH   SOLE 0 209,677 0 0
Quanterix Corp COM 74766Q101   326,977 29,013 SH   DFND 3 29,013 0 0
QuantumScape Corp COM CL A 74767V109   2,856,865 349,250 SH   DFND 1 349,250 0 0
QuantumScape Corp COM CL A 74767V109   7,470,622 913,279 SH   SOLE 0 913,279 0 0
Quest Diagnostics COM 74834L100   24,193 171 SH   DFND 3 171 0 0
Quidel Corp COM 219798105   11,404 128 SH   DFND 3 128 0 0
REGENXBIO COM 75901B107   15,449 817 SH   DFND 3 817 0 0
Rambus Inc COM 750917106   37,932 740 SH   DFND 3 740 0 0
Recursion Pharmaceuticals Inc CL A 75629V104   31,980,896 4,794,737 SH   DFND 2 4,753,348 0 41,389
Recursion Pharmaceuticals Inc CL A 75629V104   20,445,684 3,065,320 SH   DFND 1 3,065,320 0 0
Recursion Pharmaceuticals Inc CL A 75629V104   4,035,777 605,064 SH   DFND 3 605,064 0 0
Recursion Pharmaceuticals Inc CL A 75629V104   111,191,628 16,670,409 SH   SOLE 0 16,670,409 0 0
Redfin COM 75737F108   5,870,681 647,978 SH   SOLE 0 647,978 0 0
Redfin COM 75737F108   2,106,332 232,487 SH   DFND 3 232,487 0 0
Redfin COM 75737F108   45,078,257 4,975,525 SH   DFND 2 4,926,684 0 48,841
Redfin COM 75737F108   29,576,098 3,264,470 SH   DFND 1 3,264,470 0 0
Regeneron Pharmaceuticals COM 75886F107   44,370 54 SH   DFND 3 54 0 0
Relay Therapeutics Inc COM 75943R102   1,217,660 73,932 SH   DFND 1 73,932 0 0
Relay Therapeutics Inc COM 75943R102   2,973,807 180,559 SH   DFND 3 180,559 0 0
Relay Therapeutics Inc COM 75943R102   2,654,503 161,172 SH   DFND 2 161,172 0 0
Remitly Global Inc COM 75960P104   23,620,757 1,393,555 SH   DFND 2 871,778 0 521,777
Remitly Global Inc COM 75960P104   36,675,376 2,163,739 SH   DFND 3 1,701,683 0 462,056
Remitly Global Inc COM 75960P104   13,068,535 771,005 SH   SOLE 0 341,677 0 429,328
Remitly Global Inc COM 75960P104   36,913,371 2,177,780 SH   DFND 1 2,177,780 0 0
ResMed COM 761152107   2,641,457 12,062 SH   DFND 1 12,062 0 0
ResMed COM 761152107   5,639,430 25,752 SH   DFND 2 25,752 0 0
ResMed COM 761152107   6,488,455 29,629 SH   DFND 3 29,629 0 0
Research in Motion COM 09228F103   11,099 2,434 SH   DFND 3 2,434 0 0
Rexford Industrial Realty REIT COM 76169C100   40,364,260 676,685 SH   DFND 1 676,685 0 0
Rexford Industrial Realty REIT COM 76169C100   4,299,691 72,082 SH   DFND 3 72,082 0 0
Rio Tinto Spn.Adr 1:1 SPONSORED ADR 767204100   8,781 128 SH   DFND 4 128 0 0
Ritchie Bros Auctioneers (USA) COM 767744105   50,133,732 890,633 SH   DFND 2 798,486 0 92,147
Ritchie Bros Auctioneers (USA) COM 767744105   2,477 44 SH   DFND 4 44 0 0
Ritchie Bros. Auctioneers COM 767744105   36,426,270 648,310 SH   DFND 2 372,885 0 275,425
Rivian Automotive Inc COM CL A 76954A103   17,758,997 1,147,222 SH   DFND 1 1,147,222 0 0
Rivian Automotive Inc COM CL A 76954A103   27,890,734 1,801,727 SH   DFND 2 1,784,108 0 17,619
Rivian Automotive Inc COM CL A 76954A103   1,209,669 78,144 SH   DFND 3 78,144 0 0
Rivian Automotive Inc COM CL A 76954A103   4,218,037 272,483 SH   SOLE 0 272,483 0 0
Robert Half International Inc COM 770323103   10,555 131 SH   DFND 3 131 0 0
Roblox CL A 771049103   336,242,098 7,475,369 SH   SOLE 0 5,537,269 0 1,938,100
Roblox CL A 771049103   180,739,266 4,018,214 SH   DFND 1 4,018,214 0 0
Roblox CL A 771049103   689,544,480 15,330,024 SH   DFND 2 8,948,188 0 6,381,836
Roblox CL A 771049103   98,058,829 2,180,054 SH   DFND 3 1,891,307 0 288,747
Roku COM CL A 77543R102   123,153,103 1,871,059 SH   DFND 2 1,853,066 0 17,993
Roku COM CL A 77543R102   16,364,958 248,632 SH   SOLE 0 248,632 0 0
Roku COM CL A 77543R102   5,208,402 79,131 SH   DFND 3 79,131 0 0
Roku COM CL A 77543R102   79,036,919 1,200,804 SH   DFND 1 1,200,804 0 0
Rollins Inc COM 775711104   23,381 623 SH   DFND 3 623 0 0
Royalty Pharma SHS CLASS A G7709Q104   64,001,062 1,776,327 SH   DFND 3 978,224 0 798,103
Royalty Pharma SHS CLASS A G7709Q104   80,594,354 2,236,868 SH   DFND 1 2,236,868 0 0
Royalty Pharma SHS CLASS A G7709Q104   292,650,648 8,122,416 SH   SOLE 0 5,275,552 0 2,846,864
Royalty Pharma SHS CLASS A G7709Q104   244,396,498 6,783,139 SH   DFND 2 6,003,806 0 779,333
Ryanair ADR SPONSORED ADR NE 783513203   11,598 123 SH   DFND 4 123 0 0
Ryanair ADR SPONSORED ADR NE 783513203   25,789,069 273,508 SH   DFND 1 273,508 0 0
Ryanair ADR SPONSORED ADR NE 783513203   707,853,322 7,507,194 SH   DFND 2 6,348,430 0 1,158,764
Ryanair ADR SPONSORED ADR NE 783513203   8,771,893 93,031 SH   DFND 3 93,031 0 0
Ryanair ADR SPONSORED ADR NE 783513203   10,786,870 114,401 SH   SOLE 0 104,664 0 9,737
S&P Global Inc COM 78409V104   215,994,957 626,490 SH   SOLE 0 408,613 0 217,877
S&P Global Inc COM 78409V104   46,026,450 133,499 SH   DFND 3 72,937 0 60,562
S&P Global Inc COM 78409V104   183,666,219 532,721 SH   DFND 2 474,170 0 58,551
S&P Global Inc COM 78409V104   57,399,723 166,487 SH   DFND 1 166,487 0 0
SCP Pool Corporation COM 73278L105   26,934,961 78,656 SH   DFND 1 78,656 0 0
SCP Pool Corporation COM 73278L105   80,779,884 235,895 SH   DFND 2 208,003 0 27,892
SCP Pool Corporation COM 73278L105   96,519,111 281,857 SH   SOLE 0 180,731 0 101,126
SCP Pool Corporation COM 73278L105   21,794,936 63,646 SH   DFND 3 35,190 0 28,456
SKYWORKS SOLUTIONS, INC. COM 83088M102   16,045 136 SH   DFND 3 136 0 0
Sage Therapeutics Inc COM 78667J108   1,534,183 36,563 SH   DFND 2 36,563 0 0
Sage Therapeutics Inc COM 78667J108   692,760 16,510 SH   DFND 1 16,510 0 0
Sage Therapeutics Inc COM 78667J108   1,761,145 41,972 SH   DFND 3 41,972 0 0
Samsara COM CL A 79589L106   26,206,224 1,328,916 SH   DFND 1 1,328,916 0 0
Samsara COM CL A 79589L106   227,961,839 11,559,931 SH   DFND 2 4,840,070 0 6,719,861
Samsara COM CL A 79589L106   72,044,437 3,653,369 SH   SOLE 0 1,580,143 0 2,073,226
Samsara COM CL A 79589L106   44,781,083 2,270,846 SH   DFND 3 1,955,534 0 315,312
Sana Biotechnology Inc COM 799566104   5,319,139 1,626,648 SH   DFND 1 1,626,648 0 0
Sana Biotechnology Inc COM 799566104   9,044,127 2,765,788 SH   DFND 2 2,765,788 0 0
Sana Biotechnology Inc COM 799566104   615,483 188,221 SH   DFND 3 188,221 0 0
Sana Biotechnology Inc COM 799566104   20,588,809 6,296,272 SH   SOLE 0 6,296,272 0 0
Sangamo Biosciences COM 800677106   4,418 2,510 SH   DFND 3 2,510 0 0
Sarepta Therapeutics Inc COM 803607100   31,839 231 SH   DFND 3 231 0 0
Schrodinger COM 80810D103   13,524,194 513,642 SH   DFND 1 513,642 0 0
Schrodinger COM 80810D103   24,238,160 920,553 SH   DFND 2 267,012 0 653,541
Schrodinger COM 80810D103   13,020,317 494,505 SH   SOLE 0 494,505 0 0
Schrodinger COM 80810D103   9,377,456 356,151 SH   DFND 3 356,151 0 0
Scilex Hdg COM 80880W106   4,289 523 SH   DFND 3 523 0 0
Sea Ltd ADR ADR 81141R100   2,684,694 31,019 SH   DFND 4 31,019 0 0
Sea Ltd ADR ADR 81141R100   124,285,281 1,435,994 SH   DFND 3 955,353 0 480,641
Sea Ltd ADR ADR 81141R100   1,238,770,070 14,312,768 SH   DFND 2 9,616,207 0 4,696,561
Sea Ltd ADR ADR 81141R100   237,058,979 2,738,983 SH   DFND 1 2,738,983 0 0
Sea Ltd ADR ADR 81141R100   300,557,165 3,472,642 SH   SOLE 0 2,066,936 0 1,405,706
Seagen Inc COM 81181C104   25,916 128 SH   DFND 3 128 0 0
Seer COM CL A 81578P106   861 223 SH   DFND 3 223 0 0
Sei Investments Co COM 784117103   29,235 508 SH   DFND 3 508 0 0
Service Corp.Intl. COM 817565104   382,068,361 5,554,934 SH   DFND 2 4,924,010 0 630,924
Service Corp.Intl. COM 817565104   123,591,745 1,796,914 SH   DFND 1 1,796,914 0 0
Service Corp.Intl. COM 817565104   97,972,639 1,424,435 SH   DFND 3 779,499 0 644,936
Service Corp.Intl. COM 817565104   444,217,762 6,458,531 SH   SOLE 0 4,246,664 0 2,211,867
Sherwin-Williams Co COM 824348106   9,596,330 42,694 SH   DFND 2 42,694 0 0
ShockWave Medical Inc COM 82489T104   12,041,871 55,536 SH   DFND 1 55,536 0 0
ShockWave Medical Inc COM 82489T104   31,524,263 145,387 SH   DFND 2 92,512 0 52,875
ShockWave Medical Inc COM 82489T104   20,061,112 92,520 SH   DFND 3 92,520 0 0
ShockWave Medical Inc COM 82489T104   11,618,619 53,584 SH   SOLE 0 53,584 0 0
Shopify 'A' CL A 82509L107   319,114,959 6,656,549 SH   DFND 3 5,294,103 0 1,362,446
Shopify 'A' CL A 82509L107   1,805,857,948 37,669,127 SH   DFND 2 25,792,967 0 11,876,160
Shopify 'A' CL A 82509L107   669,786,759 13,971,355 SH   DFND 1 13,971,355 0 0
Shopify 'A' CL A 82509L107   4,315 90 SH   DFND 4 90 0 0
Shopify 'A' CL A 82509L107   608,551,175 12,694,017 SH   SOLE 0 8,618,452 0 4,075,565
Shopify Inc COM 82509L107   106,200 2,218 SH   DFND 3 2,218 0 0
Shopify Inc COM 82509L107   5,883,066 122,868 SH   DFND 2 122,868 0 0
Silk Road Medical COM 82710M100   11,074 283 SH   DFND 3 283 0 0
SiteOne Landscape Supply COM 82982L103   30,150,682 220,287 SH   DFND 3 120,592 0 99,695
SiteOne Landscape Supply COM 82982L103   112,094,340 818,984 SH   DFND 2 722,099 0 96,885
SiteOne Landscape Supply COM 82982L103   37,416,152 273,370 SH   DFND 1 273,370 0 0
SiteOne Landscape Supply COM 82982L103   135,107,251 987,121 SH   SOLE 0 638,189 0 348,932
Sixth Street Specialty Lending COM 83012A109   1,454,850 79,500 SH   DFND 1 79,500 0 0
Smartsheet COM 83200N103   16,826 352 SH   DFND 3 352 0 0
Snap Inc CL A 83304A106   43,253,034 3,858,433 SH   DFND 1 3,858,433 0 0
Snap Inc CL A 83304A106   66,196,788 5,905,155 SH   DFND 2 5,847,278 0 57,877
Snap Inc CL A 83304A106   2,770,249 247,123 SH   DFND 3 247,123 0 0
Snap Inc CL A 83304A106   9,789,491 873,282 SH   SOLE 0 873,282 0 0
Snap On COM 833034101   21,233 86 SH   DFND 3 86 0 0
Snowflake Inc COM 833445109   241,655,787 1,566,244 SH   DFND 2 1,503,510 0 62,734
Snowflake Inc COM 833445109   26,093,988 169,123 SH   DFND 3 113,168 0 55,955
Snowflake Inc COM 833445109   307,598,407 1,993,638 SH   SOLE 0 1,797,871 0 195,767
Snowflake Inc COM 833445109   129,668,402 840,420 SH   DFND 1 840,420 0 0
Solaredge Technologies Inc COM 83417M104   57,143 188 SH   DFND 3 188 0 0
Solaredge Technologies Inc COM 83417M104   348,631 1,147 SH   DFND 1 1,147 0 0
Solaredge Technologies Inc COM 83417M104   274,399,677 902,779 SH   DFND 2 758,022 0 144,757
Solaredge Technologies Inc COM 83417M104   8,303,002 27,317 SH   SOLE 0 0 0 27,317
Sorrento Therapeutics COM 83587F202   1,336 3,711 SH   DFND 3 3,711 0 0
Spire Global Inc COM CL A 848560108   578,518 866,045 SH   SOLE 0 866,045 0 0
Splunk Inc COM 848637104   4,607,609 48,056 SH   DFND 3 48,056 0 0
Splunk Inc COM 848637104   12,781,092 133,303 SH   DFND 2 38,049 0 95,254
Splunk Inc COM 848637104   3,628,099 37,840 SH   DFND 1 37,840 0 0
Splunk Inc COM 848637104   7,083,998 73,884 SH   SOLE 0 73,884 0 0
Spotify Technology SA SHS L8681T102   140,512,120 1,051,580 SH   DFND 1 1,051,580 0 0
Spotify Technology SA SHS L8681T102   2,952,473,934 22,096,048 SH   DFND 2 16,714,202 0 5,381,846
Spotify Technology SA SHS L8681T102   114,741,766 858,717 SH   DFND 3 694,077 0 164,640
Spotify Technology SA SHS L8681T102   3,608 27 SH   DFND 4 27 0 0
Spotify Technology SA SHS L8681T102   466,107,849 3,488,309 SH   SOLE 0 2,648,242 0 840,067
Sprout Social COM 85209W109   19,547,229 321,078 SH   DFND 1 321,078 0 0
Sprout Social COM 85209W109   18,274,776 300,177 SH   DFND 2 87,965 0 212,212
Sprout Social COM 85209W109   7,833,978 128,679 SH   DFND 3 128,679 0 0
Sprout Social COM 85209W109   14,968,566 245,870 SH   SOLE 0 245,870 0 0
Staar Surgical COM PAR $0.01 852312305   102,985,016 1,610,399 SH   DFND 2 995,254 0 615,145
Staar Surgical COM PAR $0.01 852312305   92,402,122 1,444,912 SH   DFND 1 1,444,912 0 0
Staar Surgical COM PAR $0.01 852312305   38,850,520 607,514 SH   DFND 3 485,974 0 121,540
Staar Surgical COM PAR $0.01 852312305   93,463,948 1,461,516 SH   SOLE 0 1,130,125 0 331,391
Starbucks Corp COM 855244109   10,247,329 98,409 SH   DFND 3 85,127 0 13,282
Starbucks Corp COM 855244109   23,688,950 227,494 SH   DFND 2 186,950 0 40,544
Starbucks Corp COM 855244109   41,273,800 396,368 SH   DFND 1 396,368 0 0
Starbucks Corp COM 855244109   24,327,996 233,631 SH   SOLE 0 233,631 0 0
Stitch Fix COM CL A 860897107   11,799 2,309 SH   DFND 2 2,309 0 0
Stitch Fix COM CL A 860897107   165,058 32,301 SH   DFND 3 32,301 0 0
Stratasys SHS M85548101   2,256,973 136,538 SH   DFND 3 136,538 0 0
Stratasys SHS M85548101   5,224,505 316,062 SH   DFND 2 94,180 0 221,882
Stratasys SHS M85548101   3,740,739 226,300 SH   DFND 1 226,300 0 0
Stratasys SHS M85548101   2,390,238 144,600 SH   SOLE 0 144,600 0 0
Sumo Logic COM 86646P103   11,333 946 SH   DFND 3 946 0 0
Sunpower Corp COM 867652406   16,746 1,210 SH   DFND 3 1,210 0 0
Sutro Biopharma COM 869367102   22,952 4,968 SH   DFND 2 4,968 0 0
Sutro Biopharma COM 869367102   4,816,017 1,042,428 SH   DFND 1 1,042,428 0 0
Sutro Biopharma COM 869367102   321,238 69,532 SH   DFND 3 69,532 0 0
Sutro Biopharma COM 869367102   3,468,354 750,726 SH   SOLE 0 750,726 0 0
Sweetgreen COM CL A 87043Q108   14,913,781 1,902,268 SH   DFND 1 1,902,268 0 0
Sweetgreen COM CL A 87043Q108   22,302,315 2,844,683 SH   DFND 2 2,817,068 0 27,615
Sweetgreen COM CL A 87043Q108   942,674 120,239 SH   DFND 3 120,239 0 0
Sweetgreen COM CL A 87043Q108   2,962,540 377,875 SH   SOLE 0 377,875 0 0
T. Rowe Price COM 74144T108   4,052,433 35,894 SH   DFND 3 35,894 0 0
T. Rowe Price COM 74144T108   183,350 1,624 SH   DFND 2 0 0 1,624
T. Rowe Price COM 74144T108   19,396,107 171,799 SH   DFND 1 171,799 0 0
T. Rowe Price COM 74144T108   11,508,349 101,934 SH   SOLE 0 101,934 0 0
TJX Companies COM 872540109   8,418,293 107,431 SH   DFND 2 107,431 0 0
TJX Companies COM 872540109   32,833 419 SH   DFND 3 419 0 0
TJX Companies COM 872540109   8,318,854 106,162 SH   SOLE 0 106,162 0 0
TSMC ADR SPONSORED ADR 874039100   602,832,947 6,480,681 SH   DFND 2 4,987,185 0 1,493,496
TSMC ADR SPONSORED ADR 874039100   14,418 155 SH   DFND 3 155 0 0
TSMC ADR SPONSORED ADR 874039100   14,883 160 SH   DFND 4 160 0 0
TSMC ADR SPONSORED ADR 874039100   56,868,707 611,360 SH   SOLE 0 485,596 0 125,764
Tabula Rasa HealthCare Inc COM 873379101   164,620 29,449 SH   DFND 3 29,449 0 0
Tabula Rasa HealthCare Inc COM 873379101   11,627 2,080 SH   DFND 2 2,080 0 0
Tabula Rasa HealthCare Inc COM 873379101   3,136,968 561,175 SH   DFND 1 561,175 0 0
Tabula Rasa HealthCare Inc COM 873379101   1,333,629 238,574 SH   SOLE 0 238,574 0 0
Tandem Diabetes Care COM NEW 875372203   4,184,576 103,043 SH   DFND 1 103,043 0 0
Tandem Diabetes Care COM NEW 875372203   30,498 751 SH   DFND 2 751 0 0
Tandem Diabetes Care COM NEW 875372203   437,451 10,772 SH   DFND 3 10,772 0 0
Tandem Diabetes Care COM NEW 875372203   6,025,590 148,377 SH   SOLE 0 148,377 0 0
Target Corp COM 87612E106   18,551 112 SH   DFND 3 112 0 0
Teladoc COM 87918A105   44,399,230 1,714,256 SH   DFND 1 1,714,256 0 0
Teladoc COM 87918A105   30,599,011 1,181,429 SH   DFND 2 628,758 0 552,671
Teladoc COM 87918A105   15,672,375 605,111 SH   SOLE 0 389,449 0 215,662
Teladoc COM 87918A105   34,345,601 1,326,085 SH   DFND 3 1,104,853 0 221,232
Telus Corp COM 87971M103   11,439 576 SH   DFND 3 576 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109   7,362,452 889,185 SH   DFND 1 889,185 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109   4,343,746 524,607 SH   DFND 3 43,926 0 480,681
Tencent Music Entertainment ADR SPONSORED ADS 88034P109   225,834,094 27,274,649 SH   DFND 2 19,160,307 0 8,114,342
Tencent Music Entertainment ADR SPONSORED ADS 88034P109   4,513 545 SH   DFND 4 545 0 0
Teradyne COM 880770102   64,878,200 603,462 SH   DFND 1 603,462 0 0
Teradyne COM 880770102   227,536,099 2,116,418 SH   SOLE 0 1,349,343 0 767,075
Teradyne COM 880770102   51,487,614 478,910 SH   DFND 3 265,766 0 213,144
Teradyne COM 880770102   188,938,827 1,757,407 SH   DFND 2 1,548,315 0 209,092
Tesla Inc COM 88160R101   659,060,173 3,176,806 SH   DFND 1 3,176,806 0 0
Tesla Inc COM 88160R101   2,825,946,679 13,621,646 SH   DFND 2 9,875,676 0 3,745,970
Tesla Inc COM 88160R101   390,515,235 1,882,364 SH   DFND 3 1,511,963 0 370,401
Tesla Inc COM 88160R101   1,529,740,956 7,373,667 SH   SOLE 0 5,888,761 0 1,484,906
Texas Instruments COM 882508104   15,853,260 85,228 SH   DFND 1 85,228 0 0
Texas Instruments COM 882508104   17,193,090 92,431 SH   DFND 2 66,417 0 26,014
Texas Instruments COM 882508104   8,466,431 45,516 SH   SOLE 0 45,516 0 0
Texas Instruments COM 882508104   4,825,285 25,941 SH   DFND 3 16,820 0 9,121
The Trade Desk COM CL A 88339J105   561,600,007 9,220,161 SH   DFND 1 9,220,161 0 0
The Trade Desk COM CL A 88339J105   211,779,014 3,476,917 SH   DFND 3 2,781,413 0 695,504
The Trade Desk COM CL A 88339J105   1,495,249,379 24,548,504 SH   DFND 2 17,260,976 0 7,287,528
The Trade Desk COM CL A 88339J105   522,946,155 8,585,555 SH   SOLE 0 5,289,279 0 3,296,276
Thermo Fisher Scientific COM 883556102   78,571,335 136,321 SH   DFND 1 136,321 0 0
Thermo Fisher Scientific COM 883556102   252,180,895 437,533 SH   DFND 2 390,885 0 46,648
Thermo Fisher Scientific COM 883556102   296,010,952 513,578 SH   SOLE 0 341,921 0 171,657
Thermo Fisher Scientific COM 883556102   61,300,984 106,357 SH   DFND 3 58,208 0 48,149
Toro Co COM 891092108   32,459 292 SH   DFND 3 292 0 0
Tractor Supply Co COM 892356106   41,602 177 SH   DFND 3 177 0 0
TransMedics Group COM 89377M109   2,471,751 32,639 SH   DFND 3 32,639 0 0
TransMedics Group COM 89377M109   173,043 2,285 SH   DFND 2 2,285 0 0
TransMedics Group COM 89377M109   8,428,825 111,301 SH   DFND 1 111,301 0 0
TransMedics Group COM 89377M109   8,083,950 106,747 SH   SOLE 0 106,747 0 0
Trupanion COM 898202106   7,278,433 169,700 SH   DFND 1 169,700 0 0
Trupanion COM 898202106   7,934,650 185,000 SH   SOLE 0 185,000 0 0
Trupanion COM 898202106   13,841,032 322,710 SH   DFND 2 93,427 0 229,283
Trupanion COM 898202106   5,629,484 131,254 SH   DFND 3 131,254 0 0
TuSimple Hdgs CL A 90089L108   513 349 SH   DFND 3 349 0 0
Twilio Inc CL A 90138F102   110,050,172 1,651,661 SH   DFND 1 1,651,661 0 0
Twilio Inc CL A 90138F102   163,504,290 2,453,914 SH   DFND 2 2,401,668 0 52,246
Twilio Inc CL A 90138F102   8,536,236 128,114 SH   DFND 3 117,758 0 10,356
Twilio Inc CL A 90138F102   22,852,957 342,983 SH   SOLE 0 342,983 0 0
Twist Bioscience Corp COM 90184D100   4,416,932 292,900 SH   DFND 1 292,900 0 0
Twist Bioscience Corp COM 90184D100   4,116,840 273,000 SH   SOLE 0 273,000 0 0
Twist Bioscience Corp COM 90184D100   2,176,059 144,301 SH   DFND 3 144,301 0 0
Twist Bioscience Corp COM 90184D100   5,577,021 369,829 SH   DFND 2 107,146 0 262,683
Ultragenyx COM 90400D108   4,612 115 SH   DFND 3 115 0 0
United Parcel Service CL B 911312106   9,728,599 50,150 SH   DFND 2 46,836 0 3,314
United Parcel Service CL B 911312106   14,917,831 76,900 SH   DFND 3 76,900 0 0
United Parcel Service CL B 911312106   69,067,812 356,038 SH   DFND 1 356,038 0 0
United Parcel Service CL B 911312106   47,473,815 244,723 SH   SOLE 0 244,723 0 0
UnitedHealth COM 91324P102   34,499 73 SH   DFND 3 73 0 0
Upwork Inc COM 91688F104   30,078,259 2,657,090 SH   DFND 1 2,657,090 0 0
Upwork Inc COM 91688F104   22,606,753 1,997,063 SH   DFND 2 610,913 0 1,386,150
Upwork Inc COM 91688F104   9,562,989 844,787 SH   DFND 3 771,259 0 73,528
Upwork Inc COM 91688F104   15,190,387 1,341,907 SH   SOLE 0 1,341,907 0 0
Vale SA ADR ADR 91912E105   9,973 632 SH   DFND 2 632 0 0
Varonis Systems Inc COM 922280102   37,897 1,457 SH   DFND 2 1,457 0 0
Varonis Systems Inc COM 922280102   532,555 20,475 SH   DFND 3 20,475 0 0
Veeco Instruments COM 922417100   4,161,638 196,954 SH   DFND 1 196,954 0 0
Veeco Instruments COM 922417100   10,790,901 510,691 SH   DFND 2 147,808 0 362,883
Veeco Instruments COM 922417100   4,390,708 207,795 SH   DFND 3 207,795 0 0
Veeva Systems Inc Class A COM 922475108   3,025,367 16,461 SH   DFND 2 16,461 0 0
Veeva Systems Inc Class A COM 922475108   1,404,339 7,641 SH   DFND 1 7,641 0 0
Veeva Systems Inc Class A COM 922475108   3,514,065 19,120 SH   DFND 3 19,120 0 0
Veritone COM 92347M100   3,784 649 SH   DFND 3 649 0 0
Vir Biotechnology Inc COM 92764N102   1,591,691 68,401 SH   DFND 2 68,401 0 0
Vir Biotechnology Inc COM 92764N102   1,926,198 82,776 SH   DFND 3 82,776 0 0
Vir Biotechnology Inc COM 92764N102   766,537 32,941 SH   DFND 1 32,941 0 0
Vir Biotechnology Inc COM 92764N102   88,470,399 3,801,908 SH   SOLE 0 3,801,908 0 0
Visa Inc-Class A Shares COM CL A 92826C839   11,668,682 51,755 SH   DFND 2 51,755 0 0
Visa Inc-Class A Shares COM CL A 92826C839   26,604 118 SH   DFND 3 118 0 0
Visteon Corp COM 92839U206   39,678 253 SH   DFND 3 253 0 0
Vuzix COM 92921W300   3,825 924 SH   DFND 3 924 0 0
WD-40 Co COM 929236107   14,244 80 SH   DFND 3 80 0 0
WEC Energy Group COM 92939U106   1,076,151 11,353 SH   DFND 1 11,353 0 0
Wabtec COM 929740108   9,404,947 93,063 SH   DFND 1 93,063 0 0
Wabtec COM 929740108   4,687,062 46,379 SH   DFND 2 17,999 0 28,380
Wabtec COM 929740108   2,874,854 28,447 SH   DFND 3 18,617 0 9,830
Wabtec COM 929740108   501,157 4,959 SH   SOLE 0 4,959 0 0
Wal-Mart Stores COM 931142103   20,201 137 SH   DFND 3 137 0 0
Warby Parker Inc CL A COM 93403J106   2,056,620 194,204 SH   DFND 1 194,204 0 0
Warby Parker Inc CL A COM 93403J106   56,634,282 5,347,902 SH   SOLE 0 5,347,902 0 0
Warby Parker Inc CL A COM 93403J106   647,028 61,098 SH   DFND 3 39,968 0 21,130
Warby Parker Inc CL A COM 93403J106   1,076,463 101,649 SH   DFND 2 37,222 0 64,427
Waters COM 941848103   2,792,243 9,018 SH   DFND 3 5,819 0 3,199
Waters COM 941848103   4,647,546 15,010 SH   DFND 2 5,799 0 9,211
Waters COM 941848103   9,272,799 29,948 SH   DFND 1 29,948 0 0
Waters COM 941848103   485,190 1,567 SH   SOLE 0 1,567 0 0
Watsco Inc COM 942622200   247,445,122 777,738 SH   DFND 1 777,738 0 0
Watsco Inc COM 942622200   84,520,158 265,653 SH   SOLE 0 265,653 0 0
Watsco Inc COM 942622200   30,664,261 96,380 SH   DFND 3 91,051 0 5,329
Watsco Inc COM 942622200   267,848,087 841,866 SH   DFND 2 817,075 0 24,791
Wayfair Inc Class A CL A 94419L101   71,940,892 2,094,959 SH   DFND 1 2,094,959 0 0
Wayfair Inc Class A CL A 94419L101   121,716,207 3,544,444 SH   DFND 2 3,349,490 0 194,954
Wayfair Inc Class A CL A 94419L101   11,727,213 341,503 SH   DFND 3 260,923 0 80,580
Wayfair Inc Class A CL A 94419L101   89,453,365 2,604,932 SH   SOLE 0 2,323,370 0 281,562
West Pharmaceutical Services COM 955306105   15,938 46 SH   DFND 3 46 0 0
Wheaton Precious Metals COM 962879102   1,570,787 32,616 SH   DFND 1 32,616 0 0
Williams-Sonoma Inc COM 969904101   7,665 63 SH   DFND 3 63 0 0
Wix Com SHS M98068105   800,747,396 8,023,521 SH   DFND 2 5,968,062 0 2,055,459
Wix Com SHS M98068105   43,014 431 SH   DFND 3 431 0 0
Workday Inc CL A 98138H101   133,115,237 644,501 SH   DFND 3 551,163 0 93,338
Workday Inc CL A 98138H101   887,387,337 4,296,443 SH   DFND 2 2,460,884 0 1,835,559
Workday Inc CL A 98138H101   257,971,145 1,249,013 SH   DFND 1 1,249,013 0 0
Workday Inc CL A 98138H101   235,152,193 1,138,531 SH   SOLE 0 593,388 0 545,143
XP CL A G98239109   637,763 53,729 SH   DFND 1 53,729 0 0
XP CL A G98239109   2,040,500 171,904 SH   DFND 2 12,129 0 159,775
XP CL A G98239109   2,057,653 173,349 SH   DFND 3 22,057 0 151,292
XP CL A G98239109   105,560 8,893 SH   DFND 4 8,893 0 0
XPEL COM 98379L100   25,074 369 SH   DFND 3 369 0 0
Xencor Inc COM 98401F105   58,011 2,080 SH   DFND 2 2,080 0 0
Xencor Inc COM 98401F105   827,608 29,674 SH   DFND 3 29,674 0 0
Xperi COM 98423J101   6,328 579 SH   DFND 3 579 0 0
Xylem COM 98419M100   115,706,169 1,105,121 SH   DFND 1 1,105,121 0 0
Xylem COM 98419M100   71,726,829 685,070 SH   DFND 2 419,690 0 265,380
Xylem COM 98419M100   116,019,955 1,108,118 SH   DFND 3 875,142 0 232,976
Xylem COM 98419M100   33,975,883 324,507 SH   SOLE 0 97,898 0 226,609
Zillow Group Inc Class A CL A 98954M101   1,354,263 30,990 SH   DFND 1 30,990 0 0
Zillow Group Inc Class A CL A 98954M101   6,699,734 153,312 SH   DFND 2 45,088 0 108,224
Zillow Group Inc Class A CL A 98954M101   2,363,646 54,088 SH   DFND 3 54,088 0 0
Zillow Group Inc Class A CL A 98954M101   3,969,708 90,840 SH   SOLE 0 90,840 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200   10,596,890 238,293 SH   DFND 3 238,293 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200   25,951,491 583,573 SH   SOLE 0 583,573 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200   30,056,250 675,877 SH   DFND 2 195,505 0 480,372
Zillow Group Inc Class C CL C CAP STK 98954M200   43,387,111 975,649 SH   DFND 1 975,649 0 0
Zoom Video Communications Inc CL A 98980L101   154,432,003 2,091,441 SH   SOLE 0 1,612,406 0 479,035
Zoom Video Communications Inc CL A 98980L101   41,492,837 561,929 SH   DFND 3 483,971 0 77,958
Zoom Video Communications Inc CL A 98980L101   316,095,896 4,280,822 SH   DFND 2 2,673,954 0 1,606,868
Zoom Video Communications Inc CL A 98980L101   102,995,724 1,394,850 SH   DFND 1 1,394,850 0 0
ZoomInfo Technologies COM 98980F104   11,021 446 SH   DFND 3 446 0 0
Zuora Inc Class A COM CL A 98983V106   7,720,588 781,436 SH   SOLE 0 781,436 0 0
Zuora Inc Class A COM CL A 98983V106   6,773,372 685,564 SH   DFND 3 685,564 0 0
Zuora Inc Class A COM CL A 98983V106   16,133,487 1,632,944 SH   DFND 2 472,046 0 1,160,898
Zuora Inc Class A COM CL A 98983V106   19,861,013 2,010,224 SH   DFND 1 2,010,224 0 0
Zynex COM 98986M103   5,772 481 SH   DFND 3 481 0 0
dLocal CL A G29018101   8,981,468 553,728 SH   DFND 1 553,728 0 0
dLocal CL A G29018101   3,309,659 204,048 SH   DFND 3 0 0 204,048
dLocal CL A G29018101   1,914 118 SH   DFND 2 118 0 0
iRobot COM 462726100   1,206,035 27,636 SH   DFND 1 27,636 0 0
iRobot COM 462726100   2,892,983 66,292 SH   DFND 3 66,292 0 0
iRobot COM 462726100   7,667,897 175,708 SH   DFND 2 53,631 0 122,077
nLIGHT COM 65487K100   4,764 468 SH   DFND 3 468 0 0