The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1 800 FLOWERS COM INC CL A 68243Q106   120,141 12,567 SH   SOLE   12,567 0 0
2U INC COM 90214J101   82,018 13,081 SH   SOLE   13,081 0 0
3M CO COM 88579Y101   413,364 3,447 SH   SOLE   3,447 0 0
ACI WORLDWIDE INC COM 004498101   215,487 9,369 SH   SOLE   9,369 0 0
ACM RESH INC COM CL A 00108J109   585,150 75,895 SH   SOLE   75,895 0 0
ACTIVISION BLIZZARD INC COM 00507V109   2,314,413 30,234 SH   SOLE   30,234 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107   37,541 25,713 SH   SOLE   25,713 0 0
ADEIA INC COM 00676P107   642,469 67,771 SH   SOLE   67,771 0 0
ADMA BIOLOGICS INC COM 000899104   912,479 235,175 SH   SOLE   235,175 0 0
ADT INC DEL COM 00090Q103   299,256 32,994 SH   SOLE   32,994 0 0
ADVANCE AUTO PARTS INC COM 00751Y106   295,971 2,013 SH   SOLE   2,013 0 0
AFFIMED N V COM N01045108   110,443 89,067 SH   SOLE   89,067 0 0
AGILYSYS INC COM 00847J105   366,735 4,634 SH   SOLE   4,634 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104   391,969 13,959 SH   SOLE   13,959 0 0
AGNC INVT CORP COM 00123Q104   1,572,269 151,910 SH   SOLE   151,910 0 0
AGORA INC ADS 00851L103   1,115,699 285,345 SH   SOLE   285,345 0 0
AKAMAI TECHNOLOGIES INC COM 00971T101   2,547,968 30,225 SH   SOLE   30,225 0 0
ALARM COM HLDGS INC COM 011642105   600,390 12,134 SH   SOLE   12,134 0 0
ALAUNOS THERAPEUTICS INC COM 98973P101   202,502 311,974 SH   SOLE   311,974 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102   1,827,868 20,750 SH   SOLE   20,750 0 0
ALLAKOS INC COM 01671P100   654,849 77,773 SH   SOLE   77,773 0 0
ALLY FINL INC COM 02005N100   1,110,519 45,420 SH   SOLE   45,420 0 0
ALPHABET INC CAP STK CL A 02079K305   951,119 10,780 SH   SOLE   10,780 0 0
ALTUS POWER INC COM CL A 02217A102   96,424 14,789 SH   SOLE   14,789 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206   115,759 95,669 SH   SOLE   95,669 0 0
AMAZON COM INC COM 023135106   1,733,424 20,636 SH   SOLE   20,636 0 0
AMBAC FINL GROUP INC COM NEW 023139884   1,613,584 92,522 SH   SOLE   92,522 0 0
AMBARELLA INC SHS G037AX101   5,215,767 63,429 SH   SOLE   63,429 0 0
AMEDISYS INC COM 023436108   1,194,622 14,300 SH   SOLE   14,300 0 0
AMERICAN HOMES 4 RENT CL A 02665T306   337,689 11,204 SH   SOLE   11,204 0 0
AMERISOURCEBERGEN CORP COM 03073E105   1,123,514 6,780 SH   SOLE   6,780 0 0
AMETEK INC COM 031100100   229,001 1,639 SH   SOLE   1,639 0 0
AMGEN INC COM 031162100   360,605 1,373 SH   SOLE   1,373 0 0
ANIKA THERAPEUTICS INC COM 035255108   633,766 21,411 SH   SOLE   21,411 0 0
APA CORPORATION COM 03743Q108   989,009 21,187 SH   SOLE   21,187 0 0
APPLE HOSPITALITY REIT INC COM NEW 03784Y200   204,241 12,943 SH   SOLE   12,943 0 0
APPLE INC COM 037833100   1,630,362 12,548 SH   SOLE   12,548 0 0
APPLE INC COM 037833100   259,860 2,000 SH Put SOLE   2,000 0 0
APTARGROUP INC COM 038336103   404,067 3,674 SH   SOLE   3,674 0 0
ARAMARK COM 03852U106   477,808 11,558 SH   SOLE   11,558 0 0
ARDELYX INC COM 039697107   286,724 100,605 SH   SOLE   100,605 0 0
ARDMORE SHIPPING CORP COM Y0207T100   754,940 52,390 SH   SOLE   52,390 0 0
ARES CAPITAL CORP COM 04010L103   1,061,009 57,445 SH   SOLE   57,445 0 0
ARGENX SE SPONSORED ADR 04016X101   270,485 714 SH   SOLE   714 0 0
ARMSTRONG WORLD INDS INC NEW COM 04247X102   578,008 8,427 SH   SOLE   8,427 0 0
ARROW ELECTRS INC COM 042735100   908,922 8,692 SH   SOLE   8,692 0 0
ARS PHARMACEUTICALS INC COM 82835W108   126,517 14,832 SH   SOLE   14,832 0 0
ATARA BIOTHERAPEUTICS INC COM 046513107   654,970 199,686 SH   SOLE   199,686 0 0
AUTODESK INC COM 052769106   1,059,927 5,672 SH   SOLE   5,672 0 0
AUTOHOME INC SP ADS RP CL A 05278C107   278,338 9,096 SH   SOLE   9,096 0 0
AVANOS MED INC COM 05350V106   354,702 13,108 SH   SOLE   13,108 0 0
AVEO PHARMACEUTICALS INC COM NEW 053588307   1,755,907 117,452 SH   SOLE   117,452 0 0
AVNET INC COM 053807103   770,020 18,519 SH   SOLE   18,519 0 0
BEL FUSE INC CL B 077347300   900,461 27,353 SH   SOLE   27,353 0 0
BLUEBIRD BIO INC COM 09609G100   468,110 67,646 SH   SOLE   67,646 0 0
BOSTON SCIENTIFIC CORP COM 101137107   2,313,500 50,000 SH   SOLE   50,000 0 0
CHENIERE ENERGY INC COM NEW 16411R208   254,032 1,694 SH   SOLE   1,694 0 0
CHEVRON CORP NEW COM 166764100   500,059 2,786 SH   SOLE   2,786 0 0
CHOICE HOTELS INTL INC COM 169905106   780,933 6,933 SH   SOLE   6,933 0 0
COPART INC COM 217204106   314,801 5,170 SH   SOLE   5,170 0 0
DISNEY WALT CO COM 254687106   335,357 3,860 SH   SOLE   3,860 0 0
DOLBY LABORATORIES INC COM CL A 25659T107   1,111,922 15,763 SH   SOLE   15,763 0 0
EATON CORP PLC SHS G29183103   289,416 1,844 SH   SOLE   1,844 0 0
EATON CORP PLC SHS G29183103   5,885,625 37,500 SH Put SOLE   37,500 0 0
EBAY INC. COM 278642103   2,468,916 59,535 SH   SOLE   59,535 0 0
ELECTRONIC ARTS INC COM 285512109   1,700,379 13,917 SH   SOLE   13,917 0 0
FOSSIL GROUP INC COM 34988V106   742,923 172,372 SH   SOLE   172,372 0 0
FUTUREFUEL CORP COM 36116M106   198,665 24,436 SH   SOLE   24,436 0 0
GANNETT CO INC COM 36472T109   312,289 153,837 SH   SOLE   153,837 0 0
GILEAD SCIENCES INC COM 375558103   66,038,396 769,230 SH   SOLE   769,230 0 0
GRANITE RIDGE RESOURCES INC COM 387432107   90,300 10,000 SH   SOLE   10,000 0 0
HAMILTON LANE INC CL A 407497106   463,960 7,263 SH   SOLE   7,263 0 0
HELIX ENERGY SOLUTIONS GRP I COM 42330P107   997,813 135,205 SH   SOLE   135,205 0 0
IMMERSION CORP COM 452521107   690,648 98,243 SH   SOLE   98,243 0 0
IMPERIAL OIL LTD COM NEW 453038408   243,547 5,000 SH   SOLE   5,000 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108   948,334 76,664 SH   SOLE   76,664 0 0
INVESCO QQQ TR UNIT SER 1 46090E103   16,642,500 62,500 SH Put SOLE   62,500 0 0
ISHARES INC MSCI CDA ETF 464286509   1,928,092 58,909 SH   SOLE   58,909 0 0
ISHARES TR RUSSELL 2000 ETF 464287655   3,286,686 18,850 SH   SOLE   18,850 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106   258,148 75,926 SH   SOLE   75,926 0 0
L3HARRIS TECHNOLOGIES INC COM 502431109   1,036,053 4,976 SH   SOLE   4,976 0 0
LHC GROUP INC COM 50187A107   563,166 3,483 SH   SOLE   3,483 0 0
MAGNACHIP SEMICONDUCTOR CORP COM 55933J203   173,687 18,497 SH   SOLE   18,497 0 0
MATRIX SVC CO COM 576853105   150,655 24,221 SH   SOLE   24,221 0 0
MCKESSON CORP COM 58155Q103   1,281,410 3,416 SH   SOLE   3,416 0 0
MKS INSTRS INC COM 55306N104   214,960 2,537 SH   SOLE   2,537 0 0
NINE ENERGY SERVICE INC COM 65441V101   920,098 63,324 SH   SOLE   63,324 0 0
ON SEMICONDUCTOR CORP COM 682189105   1,559,250 25,000 SH   SOLE   25,000 0 0
ORASURE TECHNOLOGIES INC COM 68554V108   741,697 153,879 SH   SOLE   153,879 0 0
PAGSEGURO DIGITAL LTD COM CL A G68707101   233,751 26,745 SH   SOLE   26,745 0 0
PHILLIPS 66 COM 718546104   902,374 8,670 SH   SOLE   8,670 0 0
PROTO LABS INC COM 743713109   513,127 20,099 SH   SOLE   20,099 0 0
QUDIAN INC ADR 747798106   251,243 263,634 SH   SOLE   263,634 0 0
RITE AID CORP COM 767754872   302,674 90,621 SH   SOLE   90,621 0 0
ROBERT HALF INTL INC COM 770323103   553,504 7,497 SH   SOLE   7,497 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   277,111 30,620 SH   SOLE   30,620 0 0
SCORPIO TANKERS INC SHS Y7542C130   1,880,928 34,981 SH   SOLE   34,981 0 0
SELECT SECTOR SPDR TR FINANCIAL 81369Y605   8,550,000 250,000 SH Call SOLE   250,000 0 0
SELECT SECTOR SPDR TR FINANCIAL 81369Y605   8,550,000 250,000 SH Put SOLE   250,000 0 0
SPDR GOLD TR GOLD SHS 78463V107   25,446,000 150,000 SH Call SOLE   150,000 0 0
TE CONNECTIVITY LTD SHS H84989104   893,833 7,786 SH   SOLE   7,786 0 0
THE AARONS COMPANY INC COM 00258W108   746,552 62,473 SH   SOLE   62,473 0 0
TURTLE BEACH CORP COM NEW 900450206   147,659 20,594 SH   SOLE   20,594 0 0
TUTOR PERINI CORP COM 901109108   313,227 41,487 SH   SOLE   41,487 0 0
TYLER TECHNOLOGIES INC COM 902252105   334,662 1,038 SH   SOLE   1,038 0 0
V F CORP COM 918204108   1,575,758 57,072 SH   SOLE   57,072 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   525,021 17,974 SH   SOLE   17,974 0 0
ZYMEWORKS DEL INC COM 98985Y108   936,433 119,139 SH   SOLE   119,139 0 0
BASSETT FURNITURE INDS INC COM 070203104   228,026 13,120 SH   SOLE   13,120 0 0
BAXTER INTL INC COM 071813109   1,287,757 25,265 SH   SOLE   25,265 0 0
BIO RAD LABS INC CL A 090572207   1,186,623 2,822 SH   SOLE   2,822 0 0
CAPITAL ONE FINL CORP COM 14040H105   938,431 10,095 SH   SOLE   10,095 0 0
CHURCH & DWIGHT CO INC COM 171340102   604,494 7,499 SH   SOLE   7,499 0 0
COCA COLA CO COM 191216100   1,642,919 25,828 SH   SOLE   25,828 0 0
CONNS INC COM 208242107   229,909 33,417 SH   SOLE   33,417 0 0
CROWN CASTLE INC COM 22822V101   264,769 1,952 SH   SOLE   1,952 0 0
ENTEGRIS INC COM 29362U104   684,432 10,435 SH   SOLE   10,435 0 0
EVERTEC INC COM 30040P103   231,711 7,156 SH   SOLE   7,156 0 0
F5 INC COM 315616102   895,933 6,243 SH   SOLE   6,243 0 0
G1 THERAPEUTICS INC COM 3621LQ109   98,245 18,093 SH   SOLE   18,093 0 0
GARRETT MOTION INC COM 366505105   345,453 45,335 SH   SOLE   45,335 0 0
GODADDY INC CL A 380237107   221,168 2,956 SH   SOLE   2,956 0 0
GROUPON INC COM NEW 399473206   210,648 24,551 SH   SOLE   24,551 0 0
ISHARES INC MSCI WORLD ETF 464286392   2,006,376 18,365 SH   SOLE   18,365 0 0
JOHNSON & JOHNSON COM 478160104   2,826,930 16,003 SH   SOLE   16,003 0 0
JOINT CORP COM 47973J102   179,979 12,874 SH   SOLE   12,874 0 0
KODIAK SCIENCES INC COM 50015M109   637,577 89,047 SH   SOLE   89,047 0 0
KOHLS CORP COM 500255104   452,960 17,939 SH   SOLE   17,939 0 0
LAUREATE EDUCATION INC COMMON STOCK 518613203   216,921 22,549 SH   SOLE   22,549 0 0
LIBERTY GLOBAL PLC SHS CL A G5480U104   422,877 22,339 SH   SOLE   22,339 0 0
LL FLOORING HOLDINGS INC COM 55003T107   125,601 22,349 SH   SOLE   22,349 0 0
MICROSOFT CORP COM 594918104   6,595,050 27,500 SH   SOLE   27,500 0 0
MICROSOFT CORP COM 594918104   6,595,050 27,500 SH Put SOLE   27,500 0 0
MIDCAP FINANCIAL INVSTMNT CO COM NEW 03761U502   458,633 40,231 SH   SOLE   40,231 0 0
MILLER INDS INC TENN COM NEW 600551204   899,908 33,755 SH   SOLE   33,755 0 0
NORDSON CORP COM 655663102   551,273 2,319 SH   SOLE   2,319 0 0
PAYPAL HLDGS INC COM 70450Y103   1,885,265 26,471 SH   SOLE   26,471 0 0
QURATE RETAIL INC COM SER A 74915M100   1,176,940 722,049 SH   SOLE   722,049 0 0
RENAISSANCERE HLDGS LTD COM G7496G103   540,531 2,934 SH   SOLE   2,934 0 0
SELECT SECTOR SPDR TR TECHNOLOGY 81369Y803   6,222,000 50,000 SH Call SOLE   50,000 0 0
SEMTECH CORP COM 816850101   263,460 9,183 SH   SOLE   9,183 0 0
SIGNATURE BK NEW YORK N Y COM 82669G104   359,832 3,123 SH   SOLE   3,123 0 0
SIXTH STREET SPECIALTY LENDI COM 83012A109   410,468 23,060 SH   SOLE   23,060 0 0
SOLARIS OILFIELD INFRASTRUCT COM CL A 83418M103   170,866 17,207 SH   SOLE   17,207 0 0
STARWOOD PPTY TR INC COM 85571B105   846,223 46,166 SH   SOLE   46,166 0 0
TEEKAY CORPORATION COM Y8564W103   577,538 127,211 SH   SOLE   127,211 0 0
TEEKAY TANKERS LTD CL A Y8565N300   768,617 24,947 SH   SOLE   24,947 0 0
TIDEWATER INC NEW COM 88642R109   391,052 10,612 SH   SOLE   10,612 0 0
VISA INC COM CL A 92826C839   14,583,090 70,192 SH   SOLE   70,192 0 0
WATSCO INC COM 942622200   1,341,273 5,378 SH   SOLE   5,378 0 0
ZHIHU INC ADS 98955N108   394,130 303,177 SH   SOLE   303,177 0 0
AZURE PWR GLOBAL LTD SHS V0393H103   224,193 52,017 SH   SOLE   52,017 0 0
BERKELEY LTS INC COM 084310101   270,208 100,824 SH   SOLE   100,824 0 0
BLUEGREEN VACATIONS HLDG COR CLASS A 096308101   503,967 20,191 SH   SOLE   20,191 0 0
BOOKING HOLDINGS INC COM 09857L108   10,525,807 5,223 SH   SOLE   5,223 0 0
BRANDYWINE RLTY TR SH BEN INT NEW 105368203   431,533 70,168 SH   SOLE   70,168 0 0
BRIGHTHOUSE FINL INC COM 10922N103   489,987 9,557 SH   SOLE   9,557 0 0
CARDINAL HEALTH INC COM 14149Y108   2,590,980 33,706 SH   SOLE   33,706 0 0
COGNYTE SOFTWARE LTD ORD SHS M25133105   397,306 127,751 SH   SOLE   127,751 0 0
DHT HOLDINGS INC SHS NEW Y2065G121   190,290 21,429 SH   SOLE   21,429 0 0
ENSTAR GROUP LIMITED SHS G3075P101   1,629,294 7,052 SH   SOLE   7,052 0 0
EXXON MOBIL CORP COM 30231G102   1,433,238 12,994 SH   SOLE   12,994 0 0
FREEPORT-MCMORAN INC CL B 35671D857   494,000 13,000 SH   SOLE   13,000 0 0
GENWORTH FINL INC COM CL A 37247D106   808,587 152,852 SH   SOLE   152,852 0 0
GLOBAL PMTS INC COM 37940X102   732,187 7,372 SH   SOLE   7,372 0 0
HALLADOR ENERGY COMPANY COM 40609P105   553,196 55,375 SH   SOLE   55,375 0 0
HEICO CORP NEW COM 422806109   401,922 2,616 SH   SOLE   2,616 0 0
HELLO GROUP INC ADS 423403104   618,147 68,836 SH   SOLE   68,836 0 0
INTEL CORP COM 458140100   1,508,889 57,090 SH   SOLE   57,090 0 0
INVESCO QQQ TR UNIT SER 1 46090E103   7,322,700 27,500 SH Call SOLE   27,500 0 0
ISHARES TR CHINA LG-CAP ETF 464287184   158,480 5,600 SH Call SOLE   5,600 0 0
ISHARES TR ISHARES BIOTECH 464287556   151,839,380 1,156,519 SH   SOLE   1,156,519 0 0
KILROY RLTY CORP COM 49427F108   293,041 7,578 SH   SOLE   7,578 0 0
KRANESHARES TR CSI CHI INTERNET 500767306   9,775,649 323,697 SH   SOLE   323,697 0 0
LEXINFINTECH HLDGS LTD ADR 528877103   858,944 452,076 SH   SOLE   452,076 0 0
MARATHON PETE CORP COM 56585A102   2,073,255 17,813 SH   SOLE   17,813 0 0
MARSH & MCLENNAN COS INC COM 571748102   654,308 3,954 SH   SOLE   3,954 0 0
MONSTER BEVERAGE CORP NEW COM 61174X109   455,362 4,485 SH   SOLE   4,485 0 0
MURPHY USA INC COM 626755102   288,206 1,031 SH   SOLE   1,031 0 0
NATIONAL PRESTO INDS INC COM 637215104   882,997 12,898 SH   SOLE   12,898 0 0
NEW MTN FIN CORP COM 647551100   598,213 48,360 SH   SOLE   48,360 0 0
NORDIC AMERICAN TANKERS LIMI COM G65773106   153,000 50,000 SH Call SOLE   50,000 0 0
OIL STS INTL INC COM 678026105   623,007 83,513 SH   SOLE   83,513 0 0
ON24 INC COM 68339B104   786,883 91,180 SH   SOLE   91,180 0 0
PROSPECT CAP CORP COM 74348T102   592,116 84,709 SH   SOLE   84,709 0 0
RADIAN GROUP INC COM 750236101   450,433 23,620 SH   SOLE   23,620 0 0
SKYWORKS SOLUTIONS INC COM 83088M102   1,815,765 19,925 SH   SOLE   19,925 0 0
STANLEY BLACK & DECKER INC COM 854502101   291,240 3,877 SH   SOLE   3,877 0 0
SUNRUN INC COM 86771W105   1,801,500 75,000 SH   SOLE   75,000 0 0
TEXAS INSTRS INC COM 882508104   1,142,166 6,913 SH   SOLE   6,913 0 0
UNITED STS OIL FD LP UNITS 91232N207   490,770 7,000 SH Call SOLE   7,000 0 0
UNITI GROUP INC COM 91325V108   495,809 89,658 SH   SOLE   89,658 0 0
UNIVERSAL DISPLAY CORP COM 91347P105   234,339 2,169 SH   SOLE   2,169 0 0
VEEVA SYS INC CL A COM 922475108   434,919 2,695 SH   SOLE   2,695 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100   1,104,872 3,826 SH   SOLE   3,826 0 0
VIKING THERAPEUTICS INC COM 92686J106   391,247 41,622 SH   SOLE   41,622 0 0
YELP INC CL A 985817105   889,425 32,532 SH   SOLE   32,532 0 0
YUM BRANDS INC COM 988498101   1,062,808 8,298 SH   SOLE   8,298 0 0
ZOETIS INC CL A 98978V103   1,108,504 7,564 SH   SOLE   7,564 0 0
AZZ INC COM 002474104   472,551 11,755 SH   SOLE   11,755 0 0
BLACKSTONE INC COM 09260D107   1,986,882 26,781 SH   SOLE   26,781 0 0
BRIGHTCOVE INC COM 10921T101   152,957 29,246 SH   SOLE   29,246 0 0
BROWN FORMAN CORP CL B 115637209   533,781 8,127 SH   SOLE   8,127 0 0
COMMERCE BANCSHARES INC COM 200525103   338,852 4,978 SH   SOLE   4,978 0 0
CONTAINER STORE GROUP INC COM 210751103   177,357 41,150 SH   SOLE   41,150 0 0
DYNE THERAPEUTICS INC COM 26818M108   421,412 36,360 SH   SOLE   36,360 0 0
EASTMAN KODAK CO COM NEW 277461406   242,268 79,432 SH   SOLE   79,432 0 0
EMERGENT BIOSOLUTIONS INC COM 29089Q105   153,825 13,025 SH   SOLE   13,025 0 0
FRANKLIN STR PPTYS CORP COM 35471R106   404,731 148,253 SH   SOLE   148,253 0 0
GRACO INC COM 384109104   758,491 11,277 SH   SOLE   11,277 0 0
I MAB SPONSORED ADS 44975P103   70,224 16,800 SH   SOLE   16,800 0 0
INOVIO PHARMACEUTICALS INC COM NEW 45773H201   909,741 583,167 SH   SOLE   583,167 0 0
JELD-WEN HLDG INC COM 47580P103   231,426 23,982 SH   SOLE   23,982 0 0
LESLIES INC COM 527064109   711,074 58,237 SH   SOLE   58,237 0 0
LINDE PLC SHS G5494J103   2,452,479 7,500 SH   SOLE   7,500 0 0
MATCH GROUP INC NEW COM 57667L107   793,787 19,132 SH   SOLE   19,132 0 0
MYOVANT SCIENCES LTD COM G637AM102   215,060 7,977 SH   SOLE   7,977 0 0
PFIZER INC COM 717081103   147,291,635 2,874,544 SH   SOLE   2,874,544 0 0
PLAINS GP HLDGS L P LTD PARTNR INT A 72651A207   1,244,411 100,033 SH   SOLE   100,033 0 0
PRELUDE THERAPEUTICS INC COM 74065P101   395,336 65,453 SH   SOLE   65,453 0 0
PROCTER AND GAMBLE CO COM 742718109   770,986 5,087 SH   SOLE   5,087 0 0
QUALCOMM INC COM 747525103   844,669 7,683 SH   SOLE   7,683 0 0
SANGAMO THERAPEUTICS INC COM 800677106   518,329 165,073 SH   SOLE   165,073 0 0
SANMINA CORPORATION COM 801056102   409,795 7,153 SH   SOLE   7,153 0 0
SEASPINE HLDGS CORP COM 81255T108   93,520 11,200 SH   SOLE   11,200 0 0
SELECT SECTOR SPDR TR SBI INT-INDS 81369Y704   746,396 7,600 SH Put SOLE   7,600 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103   518,724,993 1,356,392 SH   SOLE   1,356,392 0 0
STITCH FIX INC COM CL A 860897107   129,497 41,639 SH   SOLE   41,639 0 0
TRANSOCEAN LTD REG SHS H8817H100   996,164 218,457 SH   SOLE   218,457 0 0
TYSON FOODS INC CL A 902494103   646,342 10,383 SH   SOLE   10,383 0 0
USANA HEALTH SCIENCES INC COM 90328M107   430,228 8,087 SH   SOLE   8,087 0 0
VANECK ETF TRUST GOLD MINERS ETF 92189F106   384,044 13,400 SH   SOLE   13,400 0 0
VANGUARD TAX-MANAGED FDS VAN FTSE DEV MKT 921943858   1,647,029 39,243 SH   SOLE   39,243 0 0
VIRTU FINL INC CL A 928254101   449,938 22,045 SH   SOLE   22,045 0 0
VROOM INC COM 92918V109   222,434 218,073 SH   SOLE   218,073 0 0
WILLIS TOWERS WATSON PLC LTD SHS G96629103   219,388 897 SH   SOLE   897 0 0
WOLVERINE WORLD WIDE INC COM 978097103   278,977 25,524 SH   SOLE   25,524 0 0
YELLOW CORP COM 985510106   462,224 184,153 SH   SOLE   184,153 0 0
BROADRIDGE FINL SOLUTIONS IN COM 11133T103   737,178 5,496 SH   SOLE   5,496 0 0
CODEXIS INC COM 192005106   135,704 29,121 SH   SOLE   29,121 0 0
COLGATE PALMOLIVE CO COM 194162103   1,178,462 14,957 SH   SOLE   14,957 0 0
COMTECH TELECOMMUNICATIONS C COM NEW 205826209   512,915 42,250 SH   SOLE   42,250 0 0
DENNYS CORP COM 24869P104   162,953 17,693 SH   SOLE   17,693 0 0
DOMINOS PIZZA INC COM 25754A201   347,093 1,002 SH   SOLE   1,002 0 0
ECOLAB INC COM 278865100   785,296 5,395 SH   SOLE   5,395 0 0
EDITAS MEDICINE INC COM 28106W103   127,134 14,333 SH   SOLE   14,333 0 0
EQUITY RESIDENTIAL SH BEN INT 29476L107   461,085 7,815 SH   SOLE   7,815 0 0
FERRARI N V COM N3167Y103   4,580,129 21,211 SH   SOLE   21,211 0 0
GAOTU TECHEDU INC SPONSORED ADS 36257Y109   611,990 259,318 SH   SOLE   259,318 0 0
GAP INC COM 364760108   174,705 15,488 SH   SOLE   15,488 0 0
GENERAL MTRS CO COM 37045V100   325,198 9,667 SH   SOLE   9,667 0 0
GRAHAM HLDGS CO COM CL B 384637104   308,751 511 SH   SOLE   511 0 0
GRITSTONE BIO INC COM 39868T105   414,462 120,134 SH   SOLE   120,134 0 0
HEALTH CATALYST INC COM 42225T107   157,037 14,773 SH   SOLE   14,773 0 0
HORMEL FOODS CORP COM 440452100   1,056,487 23,194 SH   SOLE   23,194 0 0
HUYA INC ADS REP SHS A 44852D108   60,435 15,300 SH   SOLE   15,300 0 0
INVESCO QQQ TR UNIT SER 1 46090E103   15,118,047 56,775 SH   SOLE   56,775 0 0
KAMAN CORP COM 483548103   463,149 20,769 SH   SOLE   20,769 0 0
LAM RESEARCH CORP COM 512807108   475,780 1,132 SH   SOLE   1,132 0 0
LENNOX INTL INC COM 526107107   498,555 2,084 SH   SOLE   2,084 0 0
LINCOLN NATL CORP IND COM 534187109   598,979 19,498 SH   SOLE   19,498 0 0
MADISON SQUARE GRDN SPRT COR CL A 55825T103   770,536 4,203 SH   SOLE   4,203 0 0
MAMMOTH ENERGY SVCS INC COM 56155L108   515,774 59,627 SH   SOLE   59,627 0 0
MARCUS CORP DEL COM 566330106   260,617 18,111 SH   SOLE   18,111 0 0
MEDTRONIC PLC SHS G5960L103   3,168,955 40,774 SH   SOLE   40,774 0 0
MODEL N INC COM 607525102   911,951 22,484 SH   SOLE   22,484 0 0
NABORS INDUSTRIES LTD SHS G6359F137   299,054 1,931 SH   SOLE   1,931 0 0
NATIONAL INSTRS CORP COM 636518102   596,710 16,171 SH   SOLE   16,171 0 0
NETAPP INC COM 64110D104   1,736,635 28,915 SH   SOLE   28,915 0 0
ORTHOFIX MED INC COM 68752M108   325,811 15,870 SH   SOLE   15,870 0 0
PATTERSON-UTI ENERGY INC COM 703481101   539,554 32,040 SH   SOLE   32,040 0 0
PBF ENERGY INC CL A 69318G106   610,558 14,972 SH   SOLE   14,972 0 0
PERFORMANCE FOOD GROUP CO COM 71377A103   660,508 11,312 SH   SOLE   11,312 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   238,416 21,853 SH   SOLE   21,853 0 0
QUOTIENT TECHNOLOGY INC COM 749119103   53,429 15,577 SH   SOLE   15,577 0 0
RESMED INC COM 761152107   674,341 3,240 SH   SOLE   3,240 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104   1,690,903 42,786 SH   SOLE   42,786 0 0
SABRA HEALTH CARE REIT INC COM 78573L106   143,330 11,531 SH   SOLE   11,531 0 0
SALESFORCE INC COM 79466L302   1,509,537 11,385 SH   SOLE   11,385 0 0
SEI INVTS CO COM 784117103   204,342 3,505 SH   SOLE   3,505 0 0
SOHU COM LTD SPONSORED ADS 83410S108   405,734 29,594 SH   SOLE   29,594 0 0
SPDR GOLD TR GOLD SHS 78463V107   8,804,316 51,900 SH   SOLE   51,900 0 0
TREDEGAR CORP COM 894650100   132,380 12,953 SH   SOLE   12,953 0 0
TRUECAR INC COM 89785L107   285,332 113,678 SH   SOLE   113,678 0 0
VANDA PHARMACEUTICALS INC COM 921659108   957,929 129,625 SH   SOLE   129,625 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105   714,523 3,036 SH   SOLE   3,036 0 0
WORLD FUEL SVCS CORP COM 981475106   965,924 35,343 SH   SOLE   35,343 0 0
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101   928,580 13,708 SH   SOLE   13,708 0 0
BLACKROCK TCP CAPITAL CORP COM 09259E108   227,188 17,557 SH   SOLE   17,557 0 0
BROOKLINE BANCORP INC DEL COM 11373M107   159,867 11,298 SH   SOLE   11,298 0 0
CBOE GLOBAL MKTS INC COM 12503M108   1,258,464 10,030 SH   SOLE   10,030 0 0
CME GROUP INC COM 12572Q105   12,579,209 74,805 SH   SOLE   74,805 0 0
CONOCOPHILLIPS COM 20825C104   816,088 6,916 SH   SOLE   6,916 0 0
CORECIVIC INC COM 21871N101   204,173 17,662 SH   SOLE   17,662 0 0
CRACKER BARREL OLD CTRY STOR COM 22410J106   565,503 5,969 SH   SOLE   5,969 0 0
DENTSPLY SIRONA INC COM 24906P109   1,460,373 45,866 SH   SOLE   45,866 0 0
ENOVIS CORPORATION COM 194014502   1,222,343 22,839 SH   SOLE   22,839 0 0
ESPERION THERAPEUTICS INC NE COM 29664W105   207,023 33,230 SH   SOLE   33,230 0 0
EURONAV NV SHS B38564108   172,922 10,148 SH   SOLE   10,148 0 0
GARMIN LTD SHS H2906T109   1,159,624 12,565 SH   SOLE   12,565 0 0
GOLUB CAP BDC INC COM 38173M102   1,173,135 89,144 SH   SOLE   89,144 0 0
HELMERICH & PAYNE INC COM 423452101   1,263,440 25,488 SH   SOLE   25,488 0 0
HF SINCLAIR CORP COM 403949100   452,221 8,715 SH   SOLE   8,715 0 0
ILLINOIS TOOL WKS INC COM 452308109   383,542 1,741 SH   SOLE   1,741 0 0
INNOVIVA INC COM 45781M101   200,936 15,165 SH   SOLE   15,165 0 0
INTUIT COM 461202103   229,251 589 SH   SOLE   589 0 0
ISHARES INC MSCI BRAZIL ETF 464286400   839,100 30,000 SH Call SOLE   30,000 0 0
ISHARES TR 20 YR TR BD ETF 464287432   199,120 2,000 SH Put SOLE   2,000 0 0
JOYY INC ADS REPSTG COM A 46591M109   756,486 23,947 SH   SOLE   23,947 0 0
KELLY SVCS INC CL A 488152208   524,475 31,034 SH   SOLE   31,034 0 0
KIMBALL INTL INC CL B 494274103   77,220 11,880 SH   SOLE   11,880 0 0
KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101   989,504 66,055 SH   SOLE   66,055 0 0
LILLY ELI & CO COM 532457108   77,192,240 211,000 SH   SOLE   211,000 0 0
MANHATTAN ASSOCIATES INC COM 562750109   408,268 3,363 SH   SOLE   3,363 0 0
MASCO CORP COM 574599106   333,457 7,145 SH   SOLE   7,145 0 0
NAVIGATOR HLDGS LTD SHS Y62132108   153,566 12,840 SH   SOLE   12,840 0 0
NETEASE INC SPONSORED ADS 64110W102   688,097 9,474 SH   SOLE   9,474 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109   581,553 4,869 SH   SOLE   4,869 0 0
OVERSEAS SHIPHOLDING GROUP I CL A NEW 69036R863   295,422 102,222 SH   SOLE   102,222 0 0
PEPSICO INC COM 713448108   1,794,134 9,931 SH   SOLE   9,931 0 0
REALTY INCOME CORP COM 756109104   315,120 4,968 SH   SOLE   4,968 0 0
REVOLVE GROUP INC CL A 76156B107   391,197 17,574 SH   SOLE   17,574 0 0
SELECT SECTOR SPDR TR FINANCIAL 81369Y605   902,880 26,400 SH   SOLE   26,400 0 0
SELECTA BIOSCIENCES INC COM 816212104   109,828 97,193 SH   SOLE   97,193 0 0
SPDR SER TR S&P METALS MNG 78464A755   475,686 9,550 SH   SOLE   9,550 0 0
SUTRO BIOPHARMA INC COM 869367102   624,132 77,244 SH   SOLE   77,244 0 0
TELEPHONE & DATA SYS INC COM NEW 879433829   118,642 11,310 SH   SOLE   11,310 0 0
VANECK ETF TRUST SEMICONDUCTR ETF 92189F676   507,350 2,500 SH   SOLE   2,500 0 0
W & T OFFSHORE INC COM 92922P106   789,146 141,424 SH   SOLE   141,424 0 0
WALMART INC COM 931142103   406,512 2,867 SH   SOLE   2,867 0 0
WHITE MTNS INS GROUP LTD COM G9618E107   1,917,831 1,356 SH   SOLE   1,356 0 0
XEROX HOLDINGS CORP COM NEW 98421M106   661,161 45,285 SH   SOLE   45,285 0 0
BLACKSTONE MTG TR INC COM CL A 09257W100   841,338 39,742 SH   SOLE   39,742 0 0
CAL MAINE FOODS INC COM NEW 128030202   786,095 14,437 SH   SOLE   14,437 0 0
CARPENTER TECHNOLOGY CORP COM 144285103   342,397 9,269 SH   SOLE   9,269 0 0
CERAGON NETWORKS LTD ORD M22013102   278,300 145,707 SH   SOLE   145,707 0 0
CYMABAY THERAPEUTICS INC COM 23257D103   461,779 73,649 SH   SOLE   73,649 0 0
DESTINATION XL GROUP INC COM 25065K104   364,905 54,060 SH   SOLE   54,060 0 0
DOVER CORP COM 260003108   564,795 4,171 SH   SOLE   4,171 0 0
DRIL-QUIP INC COM 262037104   391,085 14,394 SH   SOLE   14,394 0 0
ECHOSTAR CORP CL A 278768106   812,249 48,696 SH   SOLE   48,696 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108   1,671,264 22,400 SH   SOLE   22,400 0 0
ENDEAVOR GROUP HLDGS INC CL A COM 29260Y109   6,305,452 279,745 SH   SOLE   279,745 0 0
EXPEDITORS INTL WASH INC COM 302130109   279,857 2,693 SH   SOLE   2,693 0 0
FASTENAL CO COM 311900104   1,344,598 28,415 SH   SOLE   28,415 0 0
FIRST MAJESTIC SILVER CORP COM 32076V103   834,000 100,000 SH Call SOLE   100,000 0 0
FORD MTR CO DEL COM 345370860   709,058 60,968 SH   SOLE   60,968 0 0
GENTEX CORP COM 371901109   462,499 16,960 SH   SOLE   16,960 0 0
HARMONIC INC COM 413160102   683,453 52,172 SH   SOLE   52,172 0 0
HASBRO INC COM 418056107   996,415 16,332 SH   SOLE   16,332 0 0
HOLOGIC INC COM 436440101   812,437 10,860 SH   SOLE   10,860 0 0
HOMESTREET INC COM 43785V102   270,256 9,799 SH   SOLE   9,799 0 0
HP INC COM 40434L105   925,994 34,462 SH   SOLE   34,462 0 0
INTERNATIONAL PAPER CO COM 460146103   236,350 6,825 SH   SOLE   6,825 0 0
ISHARES INC MSCI EMRG CHN 46434G764   1,998,297 42,096 SH   SOLE   42,096 0 0
JAKKS PAC INC COM NEW 47012E403   472,650 27,024 SH   SOLE   27,024 0 0
LA Z BOY INC COM 505336107   311,516 13,651 SH   SOLE   13,651 0 0
LAMB WESTON HLDGS INC COM 513272104   233,766 2,616 SH   SOLE   2,616 0 0
LANDS END INC NEW COM 51509F105   164,900 21,726 SH   SOLE   21,726 0 0
MICRON TECHNOLOGY INC COM 595112103   2,156,487 43,147 SH   SOLE   43,147 0 0
MODERNA INC COM 60770K107   1,796,200 10,000 SH Call SOLE   10,000 0 0
MSC INDL DIRECT INC CL A 553530106   480,069 5,876 SH   SOLE   5,876 0 0
NEKTAR THERAPEUTICS COM 640268108   586,870 259,677 SH   SOLE   259,677 0 0
PACCAR INC COM 693718108   1,246,131 12,591 SH   SOLE   12,591 0 0
PENTAIR PLC SHS G7S00T104   1,203,935 26,766 SH   SOLE   26,766 0 0
PERMIAN RESOURCES CORP CLASS A COM 71424F105   148,454 15,793 SH   SOLE   15,793 0 0
PERSONALIS INC COM 71535D106   48,558 24,524 SH   SOLE   24,524 0 0
PRICE T ROWE GROUP INC COM 74144T108   261,417 2,397 SH   SOLE   2,397 0 0
QUAD / GRAPHICS INC COM CL A 747301109   174,869 42,860 SH   SOLE   42,860 0 0
RACKSPACE TECHNOLOGY INC COM 750102105   815,088 276,301 SH   SOLE   276,301 0 0
REINSURANCE GRP OF AMERICA I COM NEW 759351604   1,735,629 12,215 SH   SOLE   12,215 0 0
SELECT SECTOR SPDR TR ENERGY 81369Y506   4,465,344 51,050 SH   SOLE   51,050 0 0
SHUTTERSTOCK INC COM 825690100   501,367 9,510 SH   SOLE   9,510 0 0
SPORTSMANS WHSE HLDGS INC COM 84920Y106   369,164 39,231 SH   SOLE   39,231 0 0
SYSCO CORP COM 871829107   1,436,037 18,784 SH   SOLE   18,784 0 0
T-MOBILE US INC COM 872590104   5,916,400 42,260 SH   SOLE   42,260 0 0
TRIMBLE INC COM 896239100   1,193,216 23,600 SH   SOLE   23,600 0 0
TSAKOS ENERGY NAVIGATION LTD SHS G9108L173   1,611,550 95,189 SH   SOLE   95,189 0 0
VOYA FINANCIAL INC COM 929089100   1,181,961 19,222 SH   SOLE   19,222 0 0
VOYAGER THERAPEUTICS INC COM 92915B106   650,846 106,696 SH   SOLE   106,696 0 0
ZIFF DAVIS INC COM 48123V102   720,680 9,111 SH   SOLE   9,111 0 0
BAOZUN INC SPONSORED ADR 06684L103   1,633,985 308,299 SH   SOLE   308,299 0 0
BOISE CASCADE CO DEL COM 09739D100   202,027 2,942 SH   SOLE   2,942 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108   1,863,793 25,904 SH   SOLE   25,904 0 0
C H ROBINSON WORLDWIDE INC COM NEW 12541W209   579,483 6,329 SH   SOLE   6,329 0 0
CARLYLE SECURED LENDING INC COM 872280102   428,570 29,949 SH   SOLE   29,949 0 0
CASEYS GEN STORES INC COM 147528103   329,121 1,467 SH   SOLE   1,467 0 0
CERENCE INC COM 156727109   396,153 21,379 SH   SOLE   21,379 0 0
CHIMERA INVT CORP COM NEW 16934Q208   206,432 37,533 SH   SOLE   37,533 0 0
CHIMERIX INC COM 16934W106   317,753 170,835 SH   SOLE   170,835 0 0
COHEN & STEERS INC COM 19247A100   876,983 13,584 SH   SOLE   13,584 0 0
CONCERT PHARMACEUTICALS INC COM 206022105   490,519 83,993 SH   SOLE   83,993 0 0
CONTEXTLOGIC INC COM CL A 21077C107   1,221,200 2,503,999 SH   SOLE   2,503,999 0 0
CVS HEALTH CORP COM 126650100   746,918 8,015 SH   SOLE   8,015 0 0
DOUYU INTL HLDGS LTD SPONSORED ADS 25985W105   206,630 147,593 SH   SOLE   147,593 0 0
FS KKR CAP CORP COM 302635206   434,805 24,846 SH   SOLE   24,846 0 0
GENERAL DYNAMICS CORP COM 369550108   585,788 2,361 SH   SOLE   2,361 0 0
IDEX CORP COM 45167R104   518,766 2,272 SH   SOLE   2,272 0 0
INFOSYS LTD SPONSORED ADR 456788108   760,004 42,199 SH   SOLE   42,199 0 0
INVITAE CORP COM 46185L103   262,671 141,221 SH   SOLE   141,221 0 0
IPG PHOTONICS CORP COM 44980X109   410,016 4,331 SH   SOLE   4,331 0 0
ISHARES TR RUSSELL 2000 ETF 464287655   12,205,200 70,000 SH Call SOLE   70,000 0 0
ISHARES TR RUSSELL 2000 ETF 464287655   12,205,200 70,000 SH Put SOLE   70,000 0 0
ISHARES TR IBOXX HI YD ETF 464288513   736,300 10,000 SH Put SOLE   10,000 0 0
KANDI TECHNOLOGIES GROUP INC COM 483709101   567,279 246,643 SH   SOLE   246,643 0 0
KEURIG DR PEPPER INC COM 49271V100   1,628,271 45,661 SH   SOLE   45,661 0 0
LEXICON PHARMACEUTICALS INC COM NEW 528872302   88,397 46,281 SH   SOLE   46,281 0 0
LOEWS CORP COM 540424108   343,389 5,887 SH   SOLE   5,887 0 0
LUFAX HOLDING LTD ADS REP SHS CL A 54975P102   1,177,227 606,818 SH   SOLE   606,818 0 0
MACROGENICS INC COM 556099109   1,284,005 191,357 SH   SOLE   191,357 0 0
MCDONALDS CORP COM 580135101   825,639 3,133 SH   SOLE   3,133 0 0
MODERNA INC COM 60770K107   43,011,805 239,460 SH   SOLE   239,460 0 0
NETGEAR INC COM 64111Q104   1,038,934 57,368 SH   SOLE   57,368 0 0
NICE LTD SPONSORED ADR 653656108   499,788 2,599 SH   SOLE   2,599 0 0
NORDIC AMERICAN TANKERS LIMI COM G65773106   330,936 108,149 SH   SOLE   108,149 0 0
OAKTREE SPECIALTY LENDING CO COM 67401P108   415,772 60,520 SH   SOLE   60,520 0 0
OCWEN FINL CORP COM NEW 675746606   774,010 25,311 SH   SOLE   25,311 0 0
OVERSTOCK COM INC DEL COM 690370101   835,965 43,180 SH   SOLE   43,180 0 0
PETCO HEALTH & WELLNESS CO I COM 71601V105   259,553 27,379 SH   SOLE   27,379 0 0
PNM RES INC COM 69349H107   1,106,411 22,677 SH   SOLE   22,677 0 0
POOL CORP COM 73278L105   772,755 2,556 SH   SOLE   2,556 0 0
PRECIGEN INC COM 74017N105   118,492 77,955 SH   SOLE   77,955 0 0
QIAGEN NV SHS NEW N72482123   908,382 18,215 SH   SOLE   18,215 0 0
RAYONIER ADVANCED MATLS INC COM 75508B104   571,862 59,569 SH   SOLE   59,569 0 0
SELECT ENERGY SVCS INC CL A COM 81617J301   123,308 13,345 SH   SOLE   13,345 0 0
SELECT SECTOR SPDR TR SBI HEALTHCARE 81369Y209   2,037,750 15,000 SH Call SOLE   15,000 0 0
SIMPSON MFG INC COM 829073105   275,999 3,113 SH   SOLE   3,113 0 0
TERADYNE INC COM 880770102   721,860 8,264 SH   SOLE   8,264 0 0
TUYA INC SPONSERED ADS 90114C107   94,209 49,324 SH   SOLE   49,324 0 0
WILLIAMS SONOMA INC COM 969904101   271,556 2,363 SH   SOLE   2,363 0 0
WORLD WRESTLING ENTMT INC CL A 98156Q108   476,694 6,957 SH   SOLE   6,957 0 0
WYNDHAM HOTELS & RESORTS INC COM 98311A105   430,356 6,035 SH   SOLE   6,035 0 0
YEXT INC COM 98585N106   76,290 11,683 SH   SOLE   11,683 0 0