The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X Genomics Inc Class A CL A COM 88025U109   87,723 2,407,322 SH   DFND 1 2,407,322 0 0
10X Genomics Inc Class A CL A COM 88025U109   90,420 2,481,329 SH   DFND 2 2,169,580 0 311,749
10X Genomics Inc Class A CL A COM 88025U109   49,921 1,369,961 SH   DFND 3 1,141,271 0 228,690
10X Genomics Inc Class A CL A COM 88025U109   85,402 2,343,623 SH   SOLE 0 2,171,938 0 171,685
1Life Healthcare COM 68269G107   9 537 SH   DFND 3 537 0 0
2U COM 90214J101   2 319 SH   DFND 3 319 0 0
2seventy bio COM 901384107   3 286 SH   DFND 3 286 0 0
8x8 Inc COM 282914100   9 2,045 SH   DFND 3 2,045 0 0
908 Devices COM 65443P102   2 249 SH   DFND 3 249 0 0
A. O. Smith COM 831865209   15 263 SH   DFND 3 263 0 0
ACM Research COM 00108J109   5 660 SH   DFND 3 660 0 0
AJ Gallagher & Co COM 363576109   148,738 788,893 SH   DFND 1 788,893 0 0
AJ Gallagher & Co COM 363576109   405,588 2,151,206 SH   DFND 2 1,943,284 0 207,922
AJ Gallagher & Co COM 363576109   88,542 469,619 SH   DFND 3 286,466 0 183,153
AJ Gallagher & Co COM 363576109   406,785 2,157,554 SH   SOLE 0 1,444,359 0 713,195
Abcam Plc ADR ADS 000380204   55,080 3,539,863 SH   DFND 1 3,539,863 0 0
Abcam Plc ADR ADS 000380204   29,510 1,896,538 SH   DFND 2 933,877 0 962,661
Abcam Plc ADR ADS 000380204   104,678 6,727,348 SH   SOLE 0 3,809,476 0 2,917,872
Abcellera Biologics Inc COM 00288U106   47,984 4,736,779 SH   DFND 1 4,736,779 0 0
Abcellera Biologics Inc COM 00288U106   91,965 9,078,488 SH   DFND 2 6,141,921 0 2,936,567
Abcellera Biologics Inc COM 00288U106   40,915 4,039,015 SH   DFND 3 3,335,504 0 703,511
Abcellera Biologics Inc COM 00288U106   1 112 SH   DFND 4 112 0 0
Abcellera Biologics Inc COM 00288U106   18,663 1,842,341 SH   SOLE 0 1,260,789 0 581,552
Abiomed COM 003654100   1,137 2,991 SH   DFND 2 2,991 0 0
Acadia Pharmaceuticals Inc COM 004225108   9 544 SH   DFND 3 544 0 0
Accelerate Diagnostics COM 00430H102   0 418 SH   DFND 3 418 0 0
Accenture 'A' COM G1151C101   13 48 SH   DFND 3 48 0 0
Acutus Medical COM 005111109   0 424 SH   DFND 3 424 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107   8,843 6,056,564 SH   DFND 1 6,056,564 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107   5,049 3,458,560 SH   DFND 2 1,059,542 0 2,399,018
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107   1,886 1,291,945 SH   DFND 3 1,291,945 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107   9,290 6,362,870 SH   SOLE 0 6,362,870 0 0
Adeia Inc COM 00676P107   14 1,448 SH   DFND 3 1,448 0 0
Adicet Bio Inc COM 007002108   835 93,449 SH   DFND 1 93,449 0 0
Adicet Bio Inc COM 007002108   788 88,177 SH   SOLE 0 88,177 0 0
Adobe Systems COM 00724F101   35,007 104,023 SH   DFND 1 104,023 0 0
Adobe Systems COM 00724F101   110,363 327,944 SH   DFND 2 273,586 0 54,358
Adobe Systems COM 00724F101   24,673 73,315 SH   DFND 3 43,075 0 30,240
Adobe Systems COM 00724F101   122,621 364,368 SH   SOLE 0 241,733 0 122,635
Advanced Drainage Systems COM 00790R104   7,591 92,606 SH   DFND 2 92,606 0 0
Advanced Drainage Systems COM 00790R104   13 161 SH   DFND 3 161 0 0
Advanced Drainage Systems COM 00790R104   2,055 25,074 SH   SOLE 0 25,074 0 0
Advanced Micro Devices Inc COM 007903107   8 118 SH   DFND 3 118 0 0
Aerovironment COM 008073108   18,256 213,117 SH   DFND 1 213,117 0 0
Aerovironment COM 008073108   20,044 233,997 SH   DFND 2 70,877 0 163,120
Aerovironment COM 008073108   7,877 91,957 SH   DFND 3 91,957 0 0
Aerovironment COM 008073108   18,894 220,567 SH   SOLE 0 220,567 0 0
Affirm Holdings Inc Class A COM CL A 00827B106   31,158 3,222,140 SH   DFND 1 3,222,140 0 0
Affirm Holdings Inc Class A COM CL A 00827B106   93,698 9,689,598 SH   DFND 2 6,194,152 0 3,495,446
Affirm Holdings Inc Class A COM CL A 00827B106   10,890 1,126,137 SH   DFND 3 948,990 0 177,147
Affirm Holdings Inc Class A COM CL A 00827B106   59,773 6,181,259 SH   SOLE 0 5,149,092 0 1,032,167
Agios Pharmaceuticals Inc COM 00847X104   5 186 SH   DFND 3 186 0 0
Agnico Eagle Mines COM 008474108   1,374 26,423 SH   DFND 1 26,423 0 0
Agora Inc ADR ADS 00851L103   1,913 489,288 SH   DFND 1 489,288 0 0
Agora Inc ADR ADS 00851L103   997 255,012 SH   SOLE 0 255,012 0 0
Akili Inc COM 00974B107   1,362 1,216,300 SH   DFND 1 1,216,300 0 0
Akili Inc COM 00974B107   3,863 3,449,495 SH   SOLE 0 3,449,495 0 0
Albemarle Corp COM 012653101   101,710 469,013 SH   DFND 1 469,013 0 0
Albemarle Corp COM 012653101   212,402 979,445 SH   DFND 2 880,813 0 98,632
Albemarle Corp COM 012653101   50,701 233,797 SH   DFND 3 148,857 0 84,940
Albemarle Corp COM 012653101   221,731 1,022,461 SH   SOLE 0 707,933 0 314,528
Alector Inc COM 014442107   638 69,106 SH   DFND 1 69,106 0 0
Alector Inc COM 014442107   1,312 142,196 SH   DFND 2 142,196 0 0
Alector Inc COM 014442107   1,612 174,655 SH   DFND 3 174,655 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102   3 29 SH   DFND 4 29 0 0
Allbirds Inc COM CL A 01675A109   1,649 681,466 SH   DFND 2 242,231 0 439,235
Allbirds Inc COM CL A 01675A109   1,662 686,619 SH   SOLE 0 686,619 0 0
Alnylam Pharmaceuticals COM 02043Q107   567,478 2,387,875 SH   DFND 1 2,387,875 0 0
Alnylam Pharmaceuticals COM 02043Q107   855,022 3,597,820 SH   DFND 2 2,958,439 0 639,381
Alnylam Pharmaceuticals COM 02043Q107   289,697 1,219,007 SH   DFND 3 960,351 0 258,656
Alnylam Pharmaceuticals COM 02043Q107   523,583 2,203,169 SH   SOLE 0 1,561,968 0 641,201
Alphabet Inc Class A CAP STK CL A 02079K305   10,286 116,580 SH   DFND 1 116,580 0 0
Alphabet Inc Class A CAP STK CL A 02079K305   23,339 264,529 SH   DFND 2 229,902 0 34,627
Alphabet Inc Class A CAP STK CL A 02079K305   3,247 36,799 SH   DFND 3 24,055 0 12,744
Alphabet Inc Class A CAP STK CL A 02079K305   70,988 804,578 SH   SOLE 0 804,578 0 0
Alphabet Inc Class C CAP STK CL C 02079K107   120,552 1,358,639 SH   DFND 1 1,358,639 0 0
Alphabet Inc Class C CAP STK CL C 02079K107   417,675 4,707,256 SH   DFND 2 4,252,963 0 454,293
Alphabet Inc Class C CAP STK CL C 02079K107   87,992 991,679 SH   DFND 3 583,497 0 408,182
Alphabet Inc Class C CAP STK CL C 02079K107   362,197 4,082,009 SH   SOLE 0 2,348,168 0 1,733,841
Alteryx Inc COM 02156B103   17 336 SH   DFND 3 336 0 0
Amazon.Com COM 023135106   422,146 5,025,544 SH   DFND 1 5,025,544 0 0
Amazon.Com COM 023135106   1,551,758 18,473,307 SH   DFND 2 11,420,138 0 7,053,169
Amazon.Com COM 023135106   257,012 3,059,668 SH   DFND 3 2,438,633 0 621,035
Amazon.Com COM 023135106   947,110 11,275,122 SH   SOLE 0 8,196,078 0 3,079,044
Ambarella SHS G037AX101   23,033 280,100 SH   DFND 1 280,100 0 0
Ambarella SHS G037AX101   15,591 189,607 SH   DFND 2 57,530 0 132,077
Ambarella SHS G037AX101   6,345 77,163 SH   DFND 3 77,163 0 0
Ambarella SHS G037AX101   8,026 97,605 SH   SOLE 0 97,605 0 0
Amdocs COM G02602103   35 386 SH   DFND 3 386 0 0
Ameren COM 023608102   1,049 11,802 SH   DFND 1 11,802 0 0
American Superconductor Corp COM 030111207   2,662 723,370 SH   DFND 1 723,370 0 0
American Superconductor Corp COM 030111207   2,826 768,000 SH   SOLE 0 768,000 0 0
American Tower Corp REIT COM 03027X100   824 3,890 SH   DFND 1 3,890 0 0
American Well Corp Class A COM 03044L105   23 8,246 SH   DFND 2 8,246 0 0
American Well Corp Class A COM 03044L105   275 97,023 SH   DFND 3 97,023 0 0
Amicus Therapeutics Inc COM 03152W109   7 538 SH   DFND 3 538 0 0
Amkor Technology COM 031652100   43 1,786 SH   DFND 3 1,786 0 0
Analog Devices COM 032654105   98,003 597,469 SH   DFND 1 597,469 0 0
Analog Devices COM 032654105   174,589 1,064,371 SH   DFND 2 963,319 0 101,052
Analog Devices COM 032654105   43,794 266,988 SH   DFND 3 179,179 0 87,809
Analog Devices COM 032654105   189,207 1,153,492 SH   SOLE 0 815,584 0 337,908
Anterix COM 03676C100   5 162 SH   DFND 3 162 0 0
Apellis Pharmaceuticals COM 03753U106   15 283 SH   DFND 3 283 0 0
AppFolio COM 03783C100   24 230 SH   DFND 3 230 0 0
Appian Corp CL A 03782L101   20,840 640,039 SH   DFND 1 640,039 0 0
Appian Corp CL A 03782L101   15,321 470,537 SH   DFND 2 163,896 0 306,641
Appian Corp CL A 03782L101   5,282 162,223 SH   DFND 3 162,223 0 0
Appian Corp CL A 03782L101   9,585 294,383 SH   SOLE 0 294,383 0 0
Apple COM 037833100   46,358 356,789 SH   DFND 1 356,789 0 0
Apple COM 037833100   381 2,933 SH   DFND 2 0 0 2,933
Apple COM 037833100   8,416 64,771 SH   DFND 3 64,771 0 0
Apple COM 037833100   25,673 197,592 SH   SOLE 0 197,592 0 0
Archer-Daniels-Midland Co COM 039483102   14,374 154,806 SH   DFND 2 154,806 0 0
Archer-Daniels-Midland Co COM 039483102   22 234 SH   DFND 3 234 0 0
Archer-Daniels-Midland Co COM 039483102   3,381 36,414 SH   SOLE 0 36,414 0 0
Ares Capital Corp COM 04010L103   23,521 1,273,496 SH   DFND 1 1,273,496 0 0
Ares Capital Corp COM 04010L103   5,080 275,040 SH   DFND 3 275,040 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101   1,989 16,287 SH   DFND 1 16,287 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101   4,160 34,065 SH   DFND 2 34,065 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101   5,048 41,330 SH   DFND 3 41,330 0 0
Asensus Surgical Inc COM 04367G103   2 5,338 SH   DFND 3 5,338 0 0
AstraZeneca ADR COM 046353108   27 400 SH   DFND 3 400 0 0
Atlassian Corp Plc CL A G06242104   73,332 569,882 SH   DFND 1 569,882 0 0
Atlassian Corp Plc CL A G06242104   604,977 4,701,406 SH   DFND 2 1,950,269 0 2,751,137
Atlassian Corp Plc CL A G06242104   117,564 913,617 SH   DFND 3 767,587 0 146,030
Atlassian Corp Plc CL A G06242104   187,655 1,458,306 SH   SOLE 0 635,577 0 822,729
Aurora Innovation Class A Common COM CL A 051774107   18,146 14,996,845 SH   SOLE 0 14,996,845 0 0
AutoZone COM 053332102   6,121 2,482 SH   DFND 2 2,482 0 0
AutoZone COM 053332102   30 12 SH   DFND 3 12 0 0
AutoZone COM 053332102   4,562 1,850 SH   SOLE 0 1,850 0 0
Autodesk COM 052769106   61,398 328,559 SH   DFND 1 328,559 0 0
Autodesk COM 052769106   37,428 200,290 SH   DFND 2 121,391 0 78,899
Autodesk COM 052769106   59,423 317,989 SH   DFND 3 256,989 0 61,000
Autodesk COM 052769106   15,010 80,324 SH   SOLE 0 29,794 0 50,530
Avery Dennison Corporation COM 053611109   22 121 SH   DFND 3 121 0 0
Axon Enterprise Inc COM 05464C101   76,850 463,147 SH   DFND 1 463,147 0 0
Axon Enterprise Inc COM 05464C101   156,724 944,516 SH   DFND 2 722,991 0 221,525
Axon Enterprise Inc COM 05464C101   41,090 247,636 SH   DFND 3 179,619 0 68,017
Axon Enterprise Inc COM 05464C101   147,386 888,243 SH   SOLE 0 622,894 0 265,349
Axonics Modulation Technologies COM 05465P101   12 198 SH   DFND 3 198 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108   305,460 2,670,569 SH   DFND 2 2,546,889 0 123,680
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303   16,521 5,736,542 SH   DFND 1 5,736,542 0 0
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303   142,408 49,447,253 SH   DFND 2 27,655,636 0 21,791,617
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303   4,104 1,424,901 SH   DFND 3 1,424,901 0 0
Bandwidth COM 05988J103   22 958 SH   DFND 2 958 0 0
Bandwidth COM 05988J103   263 11,463 SH   DFND 3 11,463 0 0
Beam Therapeutics COM 07373V105   4,889 125,009 SH   DFND 1 125,009 0 0
Beam Therapeutics COM 07373V105   5,922 151,407 SH   DFND 2 45,248 0 106,159
Beam Therapeutics COM 07373V105   2,018 51,607 SH   DFND 3 51,607 0 0
Beam Therapeutics COM 07373V105   4,959 126,805 SH   SOLE 0 126,805 0 0
BeiGene Ltd SPONSORED ADR 07725L102   56,675 257,686 SH   DFND 1 257,686 0 0
BeiGene Ltd SPONSORED ADR 07725L102   458,017 2,082,462 SH   DFND 2 853,921 0 1,228,541
BeiGene Ltd SPONSORED ADR 07725L102   88,407 401,959 SH   DFND 3 336,135 0 65,824
BeiGene Ltd SPONSORED ADR 07725L102   146,615 666,612 SH   SOLE 0 283,720 0 382,892
Benefitfocus Inc COM 08180D106   3,205 306,448 SH   DFND 1 306,448 0 0
Benefitfocus Inc COM 08180D106   2,446 233,886 SH   DFND 2 81,488 0 152,398
Benefitfocus Inc COM 08180D106   1,586 151,653 SH   DFND 3 151,653 0 0
Benefitfocus Inc COM 08180D106   2,368 226,368 SH   SOLE 0 226,368 0 0
Berkeley Lights Inc COM 084310101   1,205 449,784 SH   DFND 1 449,784 0 0
Berkeley Lights Inc COM 084310101   785 293,067 SH   DFND 2 293,067 0 0
Berkeley Lights Inc COM 084310101   959 357,674 SH   DFND 3 357,674 0 0
Berkeley Lights Inc COM 084310101   661 246,776 SH   SOLE 0 246,776 0 0
Beyond Meat Inc COM 08862E109   55 4,441 SH   DFND 1 4,441 0 0
Beyond Meat Inc COM 08862E109   3 239 SH   DFND 3 239 0 0
BioCryst Pharmaceuticals COM 09058V103   19 1,687 SH   DFND 3 1,687 0 0
BioNTech ADR SPONS ADS 09075V102   77,165 513,678 SH   DFND 1 513,678 0 0
BioNTech ADR SPONS ADS 09075V102   767,365 5,108,275 SH   DFND 2 2,455,588 0 2,652,687
BioNTech ADR SPONS ADS 09075V102   119,735 797,063 SH   DFND 3 696,711 0 100,352
BioNTech ADR SPONS ADS 09075V102   3 18 SH   DFND 4 18 0 0
BioNTech ADR SPONS ADS 09075V102   195,149 1,299,089 SH   SOLE 0 567,165 0 731,924
Biomarin Pharmaceutical Inc COM 09061G101   8 82 SH   DFND 3 82 0 0
Blackline COM 09239B109   17,493 260,038 SH   DFND 1 260,038 0 0
Blackline COM 09239B109   25,069 372,663 SH   DFND 2 112,950 0 259,713
Blackline COM 09239B109   9,625 143,086 SH   DFND 3 143,086 0 0
Blackline COM 09239B109   18,874 280,576 SH   SOLE 0 280,576 0 0
Blackrock Inc COM 09247X101   17 24 SH   DFND 3 24 0 0
Blink Charging COM 09354A100   4 396 SH   DFND 3 396 0 0
Block Inc COM 852234103   7,514 119,566 SH   DFND 2 119,566 0 0
Block Inc COM 852234103   13 202 SH   DFND 3 202 0 0
Block Inc COM 852234103   2,046 32,560 SH   SOLE 0 32,560 0 0
Bluebird Bio Inc COM 09609G100   6 860 SH   DFND 3 860 0 0
Blueprint Medicines Corp COM 09627Y109   14 315 SH   DFND 3 315 0 0
Booking Holdings Inc COM 09857L108   66,704 33,099 SH   DFND 1 33,099 0 0
Booking Holdings Inc COM 09857L108   222,999 110,654 SH   DFND 2 99,537 0 11,117
Booking Holdings Inc COM 09857L108   47,726 23,682 SH   DFND 3 13,668 0 10,014
Booking Holdings Inc COM 09857L108   225,310 111,801 SH   SOLE 0 71,862 0 39,939
Boston Omaha COM 101044105   18 676 SH   DFND 3 676 0 0
Box Inc COM 10316T104   29 924 SH   DFND 3 924 0 0
Brady Corp COM 104674106   9 200 SH   DFND 3 200 0 0
Bristol Myers Squibb COM 110122108   33 458 SH   DFND 3 458 0 0
Broadridge Finl.Sltn. COM 11133T103   54,128 403,550 SH   DFND 1 403,550 0 0
Broadridge Finl.Sltn. COM 11133T103   185,853 1,385,618 SH   DFND 2 1,252,753 0 132,865
Broadridge Finl.Sltn. COM 11133T103   38,273 285,344 SH   DFND 3 166,253 0 119,091
Broadridge Finl.Sltn. COM 11133T103   179,030 1,334,753 SH   SOLE 0 863,213 0 471,540
Brookfield Renewable COM 11284V105   25,181 914,340 SH   DFND 1 914,340 0 0
Brookfield Renewable COM 11284V105   3,002 108,998 SH   DFND 3 108,998 0 0
Brunswick Corp COM 117043109   16 219 SH   DFND 3 219 0 0
Bumble Inc COM CL A 12047B105   7,597 360,894 SH   SOLE 0 360,894 0 0
Burford Capital ORD SHS G17977110   7,794 971,433 SH   DFND 1 971,433 0 0
Burford Capital ORD SHS G17977110   6,162 768,136 SH   DFND 2 682,302 0 85,834
Burning Rock Biotech Ltd ADR SPON ADS 12233L107   360 160,181 SH   DFND 1 160,181 0 0
Butterfly Network Inc COM CL A 124155102   633 257,470 SH   DFND 1 257,470 0 0
Butterfly Network Inc COM CL A 124155102   1,021 414,843 SH   DFND 2 414,843 0 0
Butterfly Network Inc COM CL A 124155102   1,616 656,806 SH   DFND 3 656,806 0 0
Butterfly Network Inc COM CL A 124155102   1,972 801,558 SH   SOLE 0 801,558 0 0
C3.ai CL A 12468P104   1 117 SH   DFND 3 117 0 0
CEVA Inc COM 157210105   3,499 136,780 SH   DFND 1 136,780 0 0
CEVA Inc COM 157210105   3,623 141,624 SH   DFND 2 44,192 0 97,432
CEVA Inc COM 157210105   1,585 61,949 SH   DFND 3 61,949 0 0
CEVA Inc COM 157210105   2,110 82,500 SH   SOLE 0 82,500 0 0
CRH Plc ADR ADR 12626K203   6 152 SH   DFND 4 152 0 0
CS Disco Inc COM 126327105   18 2,885 SH   DFND 2 2,885 0 0
CS Disco Inc COM 126327105   217 34,398 SH   DFND 3 34,398 0 0
Calavo Growers Inc COM 128246105   3 113 SH   DFND 3 113 0 0
Calix Inc COM 13100M509   57 832 SH   DFND 2 832 0 0
Calix Inc COM 13100M509   670 9,794 SH   DFND 3 9,794 0 0
Canadian Pacific Railway COM 13645T100   108,445 1,455,545 SH   DFND 2 1,229,133 0 226,412
Cardlytics Inc COM 14161W105   2,277 393,924 SH   DFND 1 393,924 0 0
Cardlytics Inc COM 14161W105   3,196 552,974 SH   DFND 2 169,868 0 383,106
Cardlytics Inc COM 14161W105   1,299 224,798 SH   DFND 3 224,798 0 0
Cardlytics Inc COM 14161W105   1,529 264,524 SH   SOLE 0 264,524 0 0
Cargurus Inc COM 141788109   35 2,532 SH   DFND 2 2,532 0 0
Cargurus Inc COM 141788109   420 29,945 SH   DFND 3 29,945 0 0
Carmax Inc COM 143130102   5,870 96,396 SH   DFND 2 96,396 0 0
Carmax Inc COM 143130102   16 257 SH   DFND 3 257 0 0
Carmax Inc COM 143130102   2,439 40,056 SH   SOLE 0 40,056 0 0
Carvana COM 146869102   7,935 1,674,036 SH   DFND 1 1,674,036 0 0
Carvana COM 146869102   38,192 8,057,301 SH   DFND 2 4,092,652 0 3,964,649
Carvana COM 146869102   5,551 1,171,163 SH   DFND 3 969,267 0 201,896
Carvana COM 146869102   15,482 3,266,281 SH   SOLE 0 2,082,893 0 1,183,388
Castle Biosciences COM 14843C105   5 225 SH   DFND 3 225 0 0
Cbre Group Inc CL A 12504L109   52,294 679,501 SH   DFND 1 679,501 0 0
Cbre Group Inc CL A 12504L109   189,987 2,468,650 SH   DFND 2 2,243,018 0 225,632
Cbre Group Inc CL A 12504L109   36,648 476,190 SH   DFND 3 278,937 0 197,253
Cbre Group Inc CL A 12504L109   169,262 2,199,344 SH   SOLE 0 1,436,766 0 762,578
Cellectis ADR SPONS ADS 15117K103   168 80,224 SH   DFND 1 80,224 0 0
Cellectis ADR SPONS ADS 15117K103   712 339,172 SH   DFND 2 296,549 0 42,623
Cellectis ADR SPONS ADS 15117K103   379 180,500 SH   SOLE 0 180,500 0 0
Celsius Holdings COM 15118V207   29 282 SH   DFND 3 282 0 0
Cemex ADR SPON ADR NEW 151290889   54,387 13,428,994 SH   DFND 1 13,428,994 0 0
Cemex ADR SPON ADR NEW 151290889   198,496 49,011,275 SH   DFND 2 11,979,832 0 37,031,443
Cemex ADR SPON ADR NEW 151290889   65,799 16,246,781 SH   DFND 3 1,636,698 0 14,610,083
Cemex ADR SPON ADR NEW 151290889   3,321 819,881 SH   DFND 4 819,881 0 0
Cemex ADR SPON ADR NEW 151290889   4,187 1,033,870 SH   SOLE 0 1,033,870 0 0
Certara COM 15687V109   19,355 1,204,414 SH   DFND 1 1,204,414 0 0
Certara COM 15687V109   63,980 3,981,331 SH   DFND 2 3,574,004 0 407,327
Certara COM 15687V109   14,042 873,782 SH   DFND 3 509,337 0 364,445
Certara COM 15687V109   66,920 4,164,282 SH   SOLE 0 2,715,300 0 1,448,982
Cerus COM 157085101   5 1,459 SH   DFND 3 1,459 0 0
ChargePoint Holdings Inc COM CL A 15961R105   74 7,719 SH   DFND 1 7,719 0 0
ChargePoint Holdings Inc COM CL A 15961R105   54,780 5,748,141 SH   SOLE 0 5,748,141 0 0
Charles River Laboratories International COM 159864107   12,214 56,054 SH   DFND 2 56,054 0 0
Charles River Laboratories International COM 159864107   32 147 SH   DFND 3 147 0 0
Charles River Laboratories International COM 159864107   3,306 15,171 SH   SOLE 0 15,171 0 0
Charles Schwab COM 808513105   79,878 959,379 SH   DFND 1 959,379 0 0
Charles Schwab COM 808513105   270,738 3,251,722 SH   DFND 2 2,927,630 0 324,092
Charles Schwab COM 808513105   57,407 689,494 SH   DFND 3 401,650 0 287,844
Charles Schwab COM 808513105   271,730 3,263,627 SH   SOLE 0 2,145,382 0 1,118,245
Chegg COM 163092109   142,632 5,644,310 SH   DFND 1 5,644,310 0 0
Chegg COM 163092109   196,167 7,762,847 SH   DFND 2 6,775,280 0 987,567
Chegg COM 163092109   26,349 1,042,714 SH   DFND 3 824,973 0 217,741
Chegg COM 163092109   87,931 3,479,654 SH   SOLE 0 2,836,922 0 642,732
Chewy Inc CL A 16679L109   149,502 4,031,888 SH   DFND 1 4,031,888 0 0
Chewy Inc CL A 16679L109   295,670 7,973,837 SH   DFND 2 7,580,658 0 393,179
Chewy Inc CL A 16679L109   33,617 906,595 SH   DFND 3 602,912 0 303,683
Chewy Inc CL A 16679L109   154,574 4,168,674 SH   SOLE 0 2,900,375 0 1,268,299
Chinook Therapeutics COM 16961L106   2,418 92,275 SH   DFND 1 92,275 0 0
Chinook Therapeutics COM 16961L106   5,452 208,101 SH   DFND 2 64,166 0 143,935
Chinook Therapeutics COM 16961L106   1,894 72,274 SH   DFND 3 72,274 0 0
Chinook Therapeutics COM 16961L106   3,067 117,058 SH   SOLE 0 117,058 0 0
Church & Dwight Co Inc COM 171340102   16 199 SH   DFND 3 199 0 0
Cisco Systems COM 17275R102   26,625 558,880 SH   DFND 1 558,880 0 0
Cisco Systems COM 17275R102   220 4,625 SH   DFND 2 0 0 4,625
Cisco Systems COM 17275R102   4,827 101,317 SH   DFND 3 101,317 0 0
Cisco Systems COM 17275R102   15,459 324,489 SH   SOLE 0 324,489 0 0
Clear Secure Inc COM 18467V109   27,430 1,000,000 SH   SOLE 0 1,000,000 0 0
Cloudflare Inc CL A COM 18915M107   180,645 3,995,685 SH   DFND 1 3,995,685 0 0
Cloudflare Inc CL A COM 18915M107   621,395 13,744,632 SH   DFND 2 8,691,460 0 5,053,172
Cloudflare Inc CL A COM 18915M107   92,849 2,053,724 SH   DFND 3 1,652,035 0 401,689
Cloudflare Inc CL A COM 18915M107   295,737 6,541,397 SH   SOLE 0 4,525,582 0 2,015,815
Clover Health Investments Corp COM CL A 18914F103   2,459 2,645,503 SH   SOLE 0 2,645,503 0 0
CoStar Group COM 22160N109   248,155 3,211,114 SH   DFND 1 3,211,114 0 0
CoStar Group COM 22160N109   471,767 6,104,641 SH   DFND 2 5,860,607 0 244,034
CoStar Group COM 22160N109   45,393 587,380 SH   DFND 3 398,964 0 188,416
CoStar Group COM 22160N109   214,173 2,771,396 SH   SOLE 0 2,032,316 0 739,080
Coca Cola COM 191216100   21,344 335,544 SH   DFND 1 335,544 0 0
Coca Cola COM 191216100   427 6,708 SH   DFND 2 0 0 6,708
Coca Cola COM 191216100   973 15,299 SH   DFND 3 15,299 0 0
Coca Cola COM 191216100   28,694 451,085 SH   SOLE 0 451,085 0 0
Codexis COM 192005106   10,021 2,150,390 SH   DFND 1 2,150,390 0 0
Codexis COM 192005106   8,258 1,772,151 SH   DFND 2 533,739 0 1,238,412
Codexis COM 192005106   3,175 681,350 SH   DFND 3 676,672 0 4,678
Codexis COM 192005106   7,487 1,606,660 SH   SOLE 0 1,606,660 0 0
Cognex Corp COM 192422103   28,228 599,200 SH   DFND 1 599,200 0 0
Cognex Corp COM 192422103   3,175 67,400 SH   DFND 2 19,300 0 48,100
Cognex Corp COM 192422103   5,842 124,000 SH   DFND 3 108,100 0 15,900
Cognex Corp COM 192422103   12,319 261,500 SH   SOLE 0 261,500 0 0
Cognizant Technology Solutions Corp CL A 192446102   10 177 SH   DFND 3 177 0 0
Cognyte Software ORD SHS M25133105   1 369 SH   DFND 3 369 0 0
Cohen & Steers Inc COM 19247A100   23 362 SH   DFND 3 362 0 0
Coherent Corp COM 19247G107   17 477 SH   DFND 3 477 0 0
Coherus BioSciences COM 19249H103   13 1,585 SH   DFND 3 1,585 0 0
Cohu COM 192576106   22 700 SH   DFND 3 700 0 0
Coinbase Global Inc COM CL A 19260Q107   2 47 SH   DFND 3 47 0 0
Coinbase Global Inc COM CL A 19260Q107   264 7,447 SH   SOLE 0 7,447 0 0
Commscope Holding Co Inc COM 20337X109   11 1,442 SH   DFND 3 1,442 0 0
Consensus Cloud Solutions COM 20848V105   1 24 SH   DFND 3 24 0 0
Consolidated Edison COM 209115104   24,242 254,344 SH   DFND 1 254,344 0 0
Consolidated Edison COM 209115104   2,101 22,039 SH   DFND 3 22,039 0 0
Cooper Cos Inc/The COM 216648402   9,890 29,910 SH   DFND 2 29,910 0 0
Copa Holdings S A CL A P31076105   31,534 379,146 SH   DFND 1 379,146 0 0
Copa Holdings S A CL A P31076105   294,235 3,537,757 SH   DFND 2 2,295,000 0 1,242,757
Copa Holdings S A CL A P31076105   55,880 671,873 SH   DFND 3 72,035 0 599,838
Copa Holdings S A CL A P31076105   2,873 34,548 SH   DFND 4 34,548 0 0
Corning COM 219350105   22 679 SH   DFND 3 679 0 0
Costco Wholesale Corporation COM 22160K105   34 75 SH   DFND 3 75 0 0
Coupang CL A 22266T109   125,567 8,536,196 SH   DFND 1 8,536,196 0 0
Coupang CL A 22266T109   1,202,576 81,752,282 SH   DFND 2 53,916,557 0 27,835,725
Coupang CL A 22266T109   125,806 8,552,417 SH   DFND 3 5,842,315 0 2,710,102
Coupang CL A 22266T109   996 67,677 SH   DFND 4 67,677 0 0
Coupang CL A 22266T109   239,295 16,267,528 SH   SOLE 0 8,755,544 0 7,511,984
Coursera Inc COM 22266M104   75,033 6,342,563 SH   DFND 1 6,342,563 0 0
Coursera Inc COM 22266M104   86,708 7,329,466 SH   DFND 2 6,666,871 0 662,595
Coursera Inc COM 22266M104   31,332 2,648,522 SH   DFND 3 2,174,868 0 473,654
Coursera Inc COM 22266M104   21,130 1,786,145 SH   SOLE 0 1,397,407 0 388,738
Credicorp COM G2519Y108   20,673 152,392 SH   DFND 1 152,392 0 0
Credicorp COM G2519Y108   116,041 855,378 SH   DFND 2 341,879 0 513,499
Credicorp COM G2519Y108   35,289 260,131 SH   DFND 3 30,503 0 229,628
Credicorp COM G2519Y108   1,956 14,418 SH   DFND 4 14,418 0 0
Crispr Therapeutics AG REG SHS H17182108   6,789 167,021 SH   DFND 1 167,021 0 0
Crispr Therapeutics AG REG SHS H17182108   361 8,880 SH   DFND 2 8,880 0 0
Crispr Therapeutics AG REG SHS H17182108   523 12,862 SH   DFND 3 8,803 0 4,059
Crispr Therapeutics AG REG SHS H17182108   3,032 74,588 SH   SOLE 0 74,588 0 0
CrowdStrike Holdings COM 22788C105   12 114 SH   DFND 3 114 0 0
Cullen/Frost Bankers COM 229899109   26,314 196,814 SH   DFND 1 196,814 0 0
Cullen/Frost Bankers COM 229899109   214 1,599 SH   DFND 2 0 0 1,599
Cullen/Frost Bankers COM 229899109   4,789 35,818 SH   DFND 3 35,818 0 0
Cullen/Frost Bankers COM 229899109   15,002 112,206 SH   SOLE 0 112,206 0 0
CyberArk Software Ltd SHS M2682V108   5,254 40,523 SH   DFND 1 40,523 0 0
CyberArk Software Ltd SHS M2682V108   20,552 158,517 SH   DFND 2 48,110 0 110,407
CyberArk Software Ltd SHS M2682V108   8,211 63,334 SH   DFND 3 63,334 0 0
CyberArk Software Ltd SHS M2682V108   7,469 57,612 SH   SOLE 0 57,612 0 0
Cytokinetics Inc COM NEW 23282W605   16 340 SH   DFND 3 340 0 0
Dada Nexus Ltd ADR ADS 23344D108   17,570 2,520,818 SH   DFND 1 2,520,818 0 0
Dada Nexus Ltd ADR ADS 23344D108   22,950 3,292,712 SH   DFND 2 3,292,712 0 0
Dada Nexus Ltd ADR ADS 23344D108   279 40,019 SH   DFND 3 40,019 0 0
Dada Nexus Ltd ADR ADS 23344D108   8,850 1,269,669 SH   SOLE 0 1,269,669 0 0
Datadog COM 23804L103   101,714 1,383,860 SH   DFND 1 1,383,860 0 0
Datadog COM 23804L103   199,608 2,715,755 SH   DFND 2 2,587,910 0 127,845
Datadog COM 23804L103   22,112 300,843 SH   DFND 3 198,046 0 102,797
Datadog COM 23804L103   100,711 1,370,214 SH   SOLE 0 970,830 0 399,384
Deere & Co COM 244199105   168,643 393,328 SH   DFND 1 393,328 0 0
Deere & Co COM 244199105   116,652 272,068 SH   DFND 2 176,942 0 95,126
Deere & Co COM 244199105   167,887 391,563 SH   DFND 3 315,699 0 75,864
Deere & Co COM 244199105   43,952 102,509 SH   SOLE 0 41,685 0 60,824
Denali Therapeutics COM 24823R105   84,239 3,029,099 SH   DFND 1 3,029,099 0 0
Denali Therapeutics COM 24823R105   124,091 4,462,094 SH   DFND 2 4,326,350 0 135,744
Denali Therapeutics COM 24823R105   11,114 399,658 SH   DFND 3 366,392 0 33,266
Denali Therapeutics COM 24823R105   201,028 7,228,623 SH   SOLE 0 7,228,623 0 0
DermTech COM 24984K105   1 286 SH   DFND 3 286 0 0
Dexcom Inc COM 252131107   260,243 2,298,154 SH   DFND 1 2,298,154 0 0
Dexcom Inc COM 252131107   1,032,073 9,114,030 SH   DFND 2 3,978,869 0 5,135,161
Dexcom Inc COM 252131107   338,573 2,989,871 SH   DFND 3 2,497,731 0 492,140
Dexcom Inc COM 252131107   328,490 2,900,830 SH   SOLE 0 1,259,829 0 1,641,001
Digimarc COM 25381B101   4,853 262,445 SH   DFND 1 262,445 0 0
Digimarc COM 25381B101   5,284 285,777 SH   DFND 2 90,925 0 194,852
Digimarc COM 25381B101   2,175 117,606 SH   DFND 3 117,606 0 0
Digimarc COM 25381B101   2,861 154,711 SH   SOLE 0 154,711 0 0
Digital Realty Trust REIT COM 253868103   504 5,029 SH   DFND 1 5,029 0 0
Docebo COM 25609L105   6,885 208,507 SH   DFND 2 185,726 0 22,781
Docebo COM 25609L105   9 267 SH   DFND 3 267 0 0
Dolby Laboratories 'A' COM 25659T107   18,331 259,861 SH   DFND 1 259,861 0 0
Dolby Laboratories 'A' COM 25659T107   8,441 119,662 SH   DFND 2 117,505 0 2,157
Dolby Laboratories 'A' COM 25659T107   3,183 45,125 SH   DFND 3 45,125 0 0
Dolby Laboratories 'A' COM 25659T107   14,107 199,988 SH   SOLE 0 199,988 0 0
Dollar General Corp COM 256677105   15 62 SH   DFND 3 62 0 0
Domo COM 257554105   5 321 SH   DFND 3 321 0 0
Donaldson COM 257651109   26 436 SH   DFND 3 436 0 0
Doordash Inc COM 25809K105   93,151 1,908,057 SH   DFND 1 1,908,057 0 0
Doordash Inc COM 25809K105   180,299 3,693,140 SH   DFND 2 3,527,587 0 165,553
Doordash Inc COM 25809K105   18,708 383,199 SH   DFND 3 255,071 0 128,128
Doordash Inc COM 25809K105   134,199 2,748,848 SH   SOLE 0 2,255,913 0 492,935
Doximity Inc CLASS A 26622P107   11,538 343,799 SH   DFND 1 343,799 0 0
Doximity Inc CLASS A 26622P107   6,911 205,936 SH   DFND 2 205,936 0 0
Doximity Inc CLASS A 26622P107   8,300 247,306 SH   DFND 3 247,306 0 0
Doximity Inc CLASS A 26622P107   10,860 323,606 SH   SOLE 0 323,606 0 0
DraftKings Inc COM CL A 26142V105   14 1,214 SH   DFND 3 1,214 0 0
Dropbox CL A 26210C104   20 881 SH   DFND 3 881 0 0
Duck Creek Technologies SHS 264120106   4 355 SH   DFND 3 355 0 0
Duolingo Inc CL A COM 26603R106   83,572 1,174,923 SH   DFND 1 1,174,923 0 0
Duolingo Inc CL A COM 26603R106   89,451 1,257,573 SH   DFND 2 1,124,825 0 132,748
Duolingo Inc CL A COM 26603R106   38,187 536,868 SH   DFND 3 438,934 0 97,934
Duolingo Inc CL A COM 26603R106   20,157 283,389 SH   SOLE 0 204,068 0 79,321
EHang Holdings Ltd ADR ADS 26853E102   28 3,314 SH   DFND 1 3,314 0 0
Eargo COM 270087109   0 263 SH   DFND 3 263 0 0
Eaton COM G29183103   28,053 178,737 SH   DFND 1 178,737 0 0
Eaton COM G29183103   88,791 565,726 SH   DFND 2 472,634 0 93,092
Eaton COM G29183103   19,675 125,360 SH   DFND 3 73,328 0 52,032
Eaton COM G29183103   91,386 582,263 SH   SOLE 0 380,177 0 202,086
Ecolab COM 278865100   60,787 417,610 SH   DFND 1 417,610 0 0
Ecolab COM 278865100   44,243 303,950 SH   DFND 2 203,667 0 100,283
Ecolab COM 278865100   58,095 399,114 SH   DFND 3 317,738 0 81,376
Ecolab COM 278865100   14,275 98,071 SH   SOLE 0 33,860 0 64,211
Edwards Lifesciences Corp COM 28176E108   3,381 45,319 SH   DFND 1 45,319 0 0
Edwards Lifesciences Corp COM 28176E108   17,710 237,370 SH   DFND 2 237,370 0 0
Edwards Lifesciences Corp COM 28176E108   8,544 114,518 SH   DFND 3 114,518 0 0
Edwards Lifesciences Corp COM 28176E108   2,856 38,284 SH   SOLE 0 38,284 0 0
Elastic ORD SHS N14506104   304,379 5,910,271 SH   DFND 2 5,009,495 0 900,776
Electronic Arts, Inc. COM 285512109   23 186 SH   DFND 3 186 0 0
Elevance Health Inc COM 036752103   223,563 435,820 SH   DFND 1 435,820 0 0
Elevance Health Inc COM 036752103   759,708 1,480,998 SH   DFND 2 1,335,094 0 145,904
Elevance Health Inc COM 036752103   163,021 317,799 SH   DFND 3 186,231 0 131,568
Elevance Health Inc COM 036752103   790,705 1,541,425 SH   SOLE 0 997,926 0 543,499
Emergent Biosolutions Inc COM 29089Q105   5 385 SH   DFND 3 385 0 0
Enanta Pharmaceuticals COM 29251M106   15 318 SH   DFND 3 318 0 0
Enphase Energy Inc COM 29355A107   254 958 SH   DFND 1 958 0 0
Enphase Energy Inc COM 29355A107   24 92 SH   DFND 3 92 0 0
Entegris Inc COM 29362U104   22,835 348,140 SH   DFND 1 348,140 0 0
Entegris Inc COM 29362U104   74,713 1,139,087 SH   DFND 2 953,800 0 185,287
Entegris Inc COM 29362U104   16,168 246,502 SH   DFND 3 143,758 0 102,744
Entegris Inc COM 29362U104   76,523 1,166,687 SH   SOLE 0 752,429 0 414,258
Estee Lauder 'A' COM 518439104   70,513 284,199 SH   DFND 1 284,199 0 0
Estee Lauder 'A' COM 518439104   257,313 1,037,092 SH   DFND 2 940,034 0 97,058
Estee Lauder 'A' COM 518439104   51,033 205,687 SH   DFND 3 119,551 0 86,136
Estee Lauder 'A' COM 518439104   254,001 1,023,744 SH   SOLE 0 678,236 0 345,508
EverQuote Inc COM CL A 30041R108   10,598 718,967 SH   DFND 1 718,967 0 0
EverQuote Inc COM CL A 30041R108   3,890 263,885 SH   DFND 2 82,566 0 181,319
EverQuote Inc COM CL A 30041R108   2,176 147,620 SH   DFND 3 147,620 0 0
EverQuote Inc COM CL A 30041R108   3,413 231,550 SH   SOLE 0 231,550 0 0
Everbridge Inc COM 29978A104   7,965 269,259 SH   DFND 1 269,259 0 0
Everbridge Inc COM 29978A104   5,910 199,794 SH   DFND 2 61,545 0 138,249
Everbridge Inc COM 29978A104   2,430 82,167 SH   DFND 3 82,167 0 0
Everbridge Inc COM 29978A104   4,391 148,446 SH   SOLE 0 148,446 0 0
Eversource Energy COM 30040W108   22,972 274,001 SH   DFND 1 274,001 0 0
Eversource Energy COM 30040W108   1,678 20,009 SH   DFND 3 20,009 0 0
Exact Sciences COM 30063P105   54,599 1,102,786 SH   DFND 1 1,102,786 0 0
Exact Sciences COM 30063P105   81,643 1,649,025 SH   DFND 2 1,076,498 0 572,527
Exact Sciences COM 30063P105   30,311 612,215 SH   DFND 3 511,641 0 100,574
Exact Sciences COM 30063P105   77,594 1,567,236 SH   SOLE 0 1,182,594 0 384,642
Exelixis COM 30161Q104   20 1,230 SH   DFND 3 1,230 0 0
Exelon Corporation COM 30161N101   988 22,861 SH   DFND 1 22,861 0 0
Expedia Group Inc COM 30212P303   15 176 SH   DFND 3 176 0 0
Expeditors Intl COM 302130109   11 107 SH   DFND 3 107 0 0
Expensify Inc COM CL A 30219Q106   6,156 697,160 SH   DFND 1 697,160 0 0
Expensify Inc COM CL A 30219Q106   29 3,256 SH   DFND 2 3,256 0 0
Expensify Inc COM CL A 30219Q106   343 38,825 SH   DFND 3 38,825 0 0
Expensify Inc COM CL A 30219Q106   3,171 359,144 SH   SOLE 0 359,144 0 0
Exponent COM 30214U102   24 242 SH   DFND 3 242 0 0
Exscientia Ltd ADR ADS 30223G102   5,635 1,057,262 SH   DFND 1 1,057,262 0 0
Exscientia Ltd ADR ADS 30223G102   10,169 1,907,859 SH   DFND 2 261,038 0 1,646,821
Exscientia Ltd ADR ADS 30223G102   1,271 238,491 SH   DFND 3 238,491 0 0
Exscientia Ltd ADR ADS 30223G102   9,139 1,714,683 SH   SOLE 0 930,650 0 784,033
FTI Consulting COM 302941109   28 179 SH   DFND 3 179 0 0
FTI Consulting COM 302941109   4,329 27,262 SH   SOLE 0 27,262 0 0
Factset Research Systems COM 303075105   29 72 SH   DFND 3 72 0 0
Farfetch ORD SHS CL A 30744W107   26,314 5,563,127 SH   DFND 1 5,563,127 0 0
Farfetch ORD SHS CL A 30744W107   108,268 22,889,620 SH   DFND 2 17,141,736 0 5,747,884
Farfetch ORD SHS CL A 30744W107   12,367 2,614,564 SH   DFND 3 1,642,514 0 972,050
Farfetch ORD SHS CL A 30744W107   75,174 15,893,113 SH   SOLE 0 9,899,377 0 5,993,736
Fastenal COM 311900104   73,835 1,560,327 SH   DFND 1 1,560,327 0 0
Fastenal COM 311900104   14,616 308,875 SH   DFND 2 229,651 0 79,224
Fastenal COM 311900104   14,764 312,012 SH   DFND 3 288,133 0 23,879
Fastenal COM 311900104   39,688 838,709 SH   SOLE 0 838,709 0 0
Fastly CL A 31188V100   2 205 SH   DFND 3 205 0 0
Fate Therapeutics COM 31189P102   4 372 SH   DFND 3 372 0 0
Ferrari NV COM N3167Y103   290,565 1,359,921 SH   SOLE 0 1,359,921 0 0
Ferrari NV COM N3167Y103   1,342,218 6,281,928 SH   DFND 2 4,831,386 0 1,450,542
Fibrogen Inc COM 31572Q808   7 467 SH   DFND 3 467 0 0
First Industrial REIT COM 32054K103   31,473 652,151 SH   DFND 1 652,151 0 0
First Industrial REIT COM 32054K103   3,394 70,327 SH   DFND 3 70,327 0 0
First Republic Bank COM 33616C100   115,725 949,419 SH   DFND 1 949,419 0 0
First Republic Bank COM 33616C100   180,486 1,480,728 SH   DFND 2 1,427,084 0 53,644
First Republic Bank COM 33616C100   10,361 85,000 SH   DFND 3 70,070 0 14,930
First Republic Bank COM 33616C100   26,049 213,707 SH   SOLE 0 213,707 0 0
Fiverr Intl ORD SHS M4R82T106   10,015 343,683 SH   DFND 1 343,683 0 0
Fiverr Intl ORD SHS M4R82T106   8,658 297,101 SH   DFND 2 91,448 0 205,653
Fiverr Intl ORD SHS M4R82T106   3,439 118,021 SH   DFND 3 118,021 0 0
Fiverr Intl ORD SHS M4R82T106   9,426 323,476 SH   SOLE 0 323,476 0 0
Floor & Decor Holdings CL A 339750101   14 196 SH   DFND 3 196 0 0
Floor & Decor Holdings CL A 339750101   2,124 30,500 SH   SOLE 0 30,500 0 0
Fortis COM 349553107   956 23,917 SH   DFND 1 23,917 0 0
Fortive Corp COM 34959J108   6,285 97,814 SH   DFND 2 97,814 0 0
Fox COM 35137L105   13 430 SH   DFND 3 430 0 0
Freshpet Inc COM 358039105   35 655 SH   DFND 2 655 0 0
Freshpet Inc COM 358039105   403 7,643 SH   DFND 3 7,643 0 0
Full Truck Alliance Co Ltd ADR SPONS ADS 35969L108   126,656 15,832,037 SH   DFND 2 15,406,674 0 425,363
Futu Hdgs ADR SPON ADR CL A 36118L106   45,484 1,118,912 SH   DFND 2 868,300 0 250,612
Futu Hdgs ADR SPON ADR CL A 36118L106   1 22 SH   DFND 4 22 0 0
GAN COM G3728V109   1 572 SH   DFND 3 572 0 0
Gentex Corp COM 371901109   14 516 SH   DFND 3 516 0 0
Ginkgo Bioworks Holdings Inc CL A COM 37611X100   37,593 22,244,609 SH   DFND 1 22,244,609 0 0
Ginkgo Bioworks Holdings Inc CL A COM 37611X100   147,789 87,449,192 SH   DFND 2 48,694,135 0 38,755,057
Ginkgo Bioworks Holdings Inc CL A COM 37611X100   22,320 13,207,385 SH   DFND 3 11,235,981 0 1,971,404
Ginkgo Bioworks Holdings Inc CL A COM 37611X100   204,956 121,275,457 SH   SOLE 0 109,922,503 0 11,352,954
GitLab CLASS A 37637K108   19 412 SH   DFND 3 412 0 0
GitLab CLASS A 37637K108   2,826 62,201 SH   SOLE 0 62,201 0 0
Glaukos Corp COM 377322102   12 269 SH   DFND 3 269 0 0
Globus Medical CL A 379577208   30 405 SH   DFND 3 405 0 0
Globus Medical CL A 379577208   4,574 61,582 SH   SOLE 0 61,582 0 0
Golub Capital BDC Inc COM 38173M102   1,607 122,100 SH   DFND 1 122,100 0 0
Goodyear Tire & Rubber Co/The COM 382550101   15 1,525 SH   DFND 3 1,525 0 0
Graco COM 384109104   24 363 SH   DFND 3 363 0 0
Grainger, WW COM 384802104   33 60 SH   DFND 3 60 0 0
HDFC Bank ADR ADR REPS 3 SHS 40415F101   79,447 1,161,335 SH   DFND 2 957,121 0 204,214
HDFC Bank ADR ADR REPS 3 SHS 40415F101   11,734 171,520 SH   DFND 3 113,837 0 57,683
HDFC Bank ADR ADR REPS 3 SHS 40415F101   125,881 1,840,090 SH   SOLE 0 1,155,012 0 685,078
HUYA ADR ADS REP SHS A 44852D108   4,521 1,144,570 SH   DFND 1 1,144,570 0 0
HUYA ADR ADS REP SHS A 44852D108   2,454 621,141 SH   SOLE 0 621,141 0 0
Halozyme Therapeutics COM 40637H109   43 763 SH   DFND 3 763 0 0
Harris Corp COM 502431109   13 61 SH   DFND 3 61 0 0
Hashicorp Inc COM CL A 418100103   72,124 2,638,056 SH   DFND 1 2,638,056 0 0
Hashicorp Inc COM CL A 418100103   101,058 3,696,339 SH   DFND 2 3,430,082 0 266,257
Hashicorp Inc COM CL A 418100103   6,928 253,397 SH   DFND 3 253,397 0 0
Hashicorp Inc COM CL A 418100103   15,911 581,960 SH   SOLE 0 581,960 0 0
Health Catalyst Inc COM 42225T107   1,085 102,104 SH   DFND 1 102,104 0 0
Health Catalyst Inc COM 42225T107   2,522 237,262 SH   DFND 2 237,262 0 0
Health Catalyst Inc COM 42225T107   2,759 259,546 SH   DFND 3 259,546 0 0
Healthcare Realty Trust REIT CL A COM 42226K105   358 18,600 SH   DFND 1 18,600 0 0
Healthcare Services Group Inc COM 421906108   2 157 SH   DFND 3 157 0 0
Heron Therapeutics Inc COM 427746102   1 308 SH   DFND 3 308 0 0
Hershey Foods Corporation COM 427866108   17,182 74,198 SH   DFND 2 74,198 0 0
Hershey Foods Corporation COM 427866108   22 96 SH   DFND 3 96 0 0
Hershey Foods Corporation COM 427866108   3,386 14,624 SH   SOLE 0 14,624 0 0
Hillenbrand COM 431571108   7 170 SH   DFND 3 170 0 0
Howard Hughes COM 44267D107   27,105 354,681 SH   DFND 1 354,681 0 0
Howard Hughes COM 44267D107   84,868 1,110,549 SH   DFND 2 996,189 0 114,360
Howard Hughes COM 44267D107   18,334 239,917 SH   DFND 3 142,291 0 97,626
Howard Hughes COM 44267D107   87,135 1,140,213 SH   SOLE 0 728,416 0 411,797
Hubbell COM 443510607   20 87 SH   DFND 3 87 0 0
Hubspot Inc COM 443573100   36 126 SH   DFND 3 126 0 0
Humana COM 444859102   28 55 SH   DFND 3 55 0 0
Hutchison China Meditech SPONSORED ADR 44842L103   2,250 152,225 SH   DFND 3 0 0 152,225
ICICI Bank ADR ADR 45104G104   78,184 3,571,689 SH   DFND 1 3,571,689 0 0
ICICI Bank ADR ADR 45104G104   60,782 2,776,684 SH   DFND 2 2,776,684 0 0
ICICI Bank ADR ADR 45104G104   18,865 861,806 SH   DFND 3 563,116 0 298,690
ICICI Bank ADR ADR 45104G104   5,297 241,978 SH   DFND 4 241,978 0 0
IPG Photonics Corp COM 44980X109   11,431 120,747 SH   DFND 1 120,747 0 0
IPG Photonics Corp COM 44980X109   10,477 110,673 SH   DFND 2 33,386 0 77,287
IPG Photonics Corp COM 44980X109   4,223 44,611 SH   DFND 3 44,611 0 0
IPG Photonics Corp COM 44980X109   8,552 90,336 SH   SOLE 0 90,336 0 0
Iac/Interactivecorp COM 44891N208   8,164 183,871 SH   DFND 1 183,871 0 0
Iac/Interactivecorp COM 44891N208   25,529 574,974 SH   DFND 2 514,486 0 60,488
Iac/Interactivecorp COM 44891N208   5,840 131,522 SH   DFND 3 78,112 0 53,410
Iac/Interactivecorp COM 44891N208   27,481 618,933 SH   SOLE 0 390,882 0 228,051
Illumina COM 452327109   320,414 1,584,638 SH   DFND 1 1,584,638 0 0
Illumina COM 452327109   1,795,405 8,879,350 SH   DFND 2 6,538,866 0 2,340,484
Illumina COM 452327109   266,649 1,318,741 SH   DFND 3 1,060,508 0 258,233
Illumina COM 452327109   1,002,988 4,960,374 SH   SOLE 0 4,089,573 0 870,801
InMode SHS M5425M103   21 596 SH   DFND 3 596 0 0
Incyte Corp COM 45337C102   13 165 SH   DFND 3 165 0 0
Infinera COM 45667G103   20 2,941 SH   DFND 3 2,941 0 0
Infosys Ltd ADR SPONSORED ADR 456788108   18,181 1,009,522 SH   DFND 1 1,009,522 0 0
Infosys Ltd ADR SPONSORED ADR 456788108   15,354 852,541 SH   DFND 2 111,463 0 741,078
Infosys Ltd ADR SPONSORED ADR 456788108   20,750 1,152,148 SH   DFND 3 443,644 0 708,504
Infosys Ltd ADR SPONSORED ADR 456788108   3,229 179,269 SH   DFND 4 179,269 0 0
Inogen Inc COM 45780L104   3 141 SH   DFND 3 141 0 0
Insmed Inc COM 457669307   14 707 SH   DFND 3 707 0 0
Inspire Medical Systems COM 457730109   41 162 SH   DFND 3 162 0 0
Intercept Pharmaceuticals Inc COM 45845P108   1 101 SH   DFND 3 101 0 0
International Game Technology SHS G4863A108   23 1,024 SH   DFND 3 1,024 0 0
Intuit COM 461202103   28,571 73,405 SH   DFND 1 73,405 0 0
Intuit COM 461202103   245 629 SH   DFND 2 0 0 629
Intuit COM 461202103   5,093 13,085 SH   DFND 3 13,085 0 0
Intuit COM 461202103   16,648 42,774 SH   SOLE 0 42,774 0 0
Intuitive Surgical COM NEW 46120E602   84,926 320,054 SH   DFND 1 320,054 0 0
Intuitive Surgical COM NEW 46120E602   696,754 2,625,791 SH   DFND 2 1,088,715 0 1,537,076
Intuitive Surgical COM NEW 46120E602   134,955 508,593 SH   DFND 3 427,273 0 81,320
Intuitive Surgical COM NEW 46120E602   216,107 814,421 SH   SOLE 0 355,601 0 458,820
Invitae COM 46185L103   1 800 SH   DFND 3 800 0 0
Ionis Pharmaceuticals COM 462222100   2,219 58,757 SH   DFND 1 58,757 0 0
Ionis Pharmaceuticals COM 462222100   4,738 125,432 SH   DFND 2 125,432 0 0
Ionis Pharmaceuticals COM 462222100   5,650 149,599 SH   DFND 3 149,599 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106   10,245 2,175,115 SH   DFND 1 2,175,115 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106   31,941 6,781,610 SH   DFND 2 398,438 0 6,383,172
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106   31,334 6,652,629 SH   DFND 3 710,232 0 5,942,397
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106   1,768 375,451 SH   DFND 4 375,451 0 0
Ivanhoe Mines COM CL A 46578C108   11 1,400 SH   DFND 2 1,400 0 0
J&J Snack Foods Corp COM 466032109   15 103 SH   DFND 3 103 0 0
JFrog Ltd ORD SHS M6191J100   12,903 604,939 SH   DFND 1 604,939 0 0
JFrog Ltd ORD SHS M6191J100   10,882 510,182 SH   DFND 2 154,375 0 355,807
JFrog Ltd ORD SHS M6191J100   4,397 206,154 SH   DFND 3 206,154 0 0
JFrog Ltd ORD SHS M6191J100   8,832 414,081 SH   SOLE 0 414,081 0 0
Jack Henry & Associates COM 426281101   11 62 SH   DFND 3 62 0 0
Jazz Pharmaceuticals SHS G50871105   27 168 SH   DFND 3 168 0 0
Joby Aviation Inc COM G65163100   30 8,944 SH   DFND 1 8,944 0 0
Joby Aviation Inc COM G65163100   25,719 7,677,200 SH   SOLE 0 7,677,200 0 0
Johnson & Johnson COM 478160104   19 108 SH   DFND 3 108 0 0
Jumia Technologies Ag ADR SPONSORED ADS 48138M105   30,097 9,376,118 SH   DFND 2 8,704,414 0 671,704
Jumia Technologies Ag ADR SPONSORED ADS 48138M105   1 374 SH   DFND 3 374 0 0
KE Holdings ADR ADR 482497104   6,925 496,061 SH   DFND 1 496,061 0 0
KE Holdings ADR ADR 482497104   16,340 1,170,495 SH   DFND 2 626,756 0 543,739
KE Holdings ADR ADR 482497104   134 9,579 SH   DFND 3 9,579 0 0
KE Holdings ADR ADR 482497104   676 48,406 SH   SOLE 0 48,406 0 0
KFORCE INC. COM 493732101   16 295 SH   DFND 3 295 0 0
Knowles Corp COM 49926D109   20 1,200 SH   DFND 3 1,200 0 0
Kulicke & Soffa Industries Inc COM 501242101   22 491 SH   DFND 3 491 0 0
Lemonade Inc COM 52567D107   20,428 1,493,277 SH   DFND 1 1,493,277 0 0
Lemonade Inc COM 52567D107   32,367 2,366,001 SH   DFND 2 2,342,942 0 23,059
Lemonade Inc COM 52567D107   1,049 76,651 SH   DFND 3 76,651 0 0
Lemonade Inc COM 52567D107   13,068 955,275 SH   SOLE 0 955,275 0 0
LendingTree COM 52603B107   3,950 185,194 SH   DFND 1 185,194 0 0
LendingTree COM 52603B107   4,046 189,694 SH   DFND 2 58,286 0 131,408
LendingTree COM 52603B107   1,533 71,848 SH   DFND 3 71,848 0 0
LendingTree COM 52603B107   2,500 117,207 SH   SOLE 0 117,207 0 0
Liberty Broadband Corp COM 530307305   9 113 SH   DFND 3 113 0 0
Lightspeed POS COM 53229C107   4 310 SH   DFND 3 310 0 0
Lilium N.V. CL A COM N52586109   11 10,039 SH   DFND 1 10,039 0 0
Lilium N.V. CL A COM N52586109   1,276 1,118,923 SH   DFND 2 1,118,923 0 0
Lilium N.V. CL A COM N52586109   20,178 17,699,615 SH   SOLE 0 17,699,615 0 0
Lincoln Electric Holdings Inc COM 533900106   13 91 SH   DFND 3 91 0 0
LivePerson Inc COM 538146101   2,982 294,091 SH   DFND 1 294,091 0 0
LivePerson Inc COM 538146101   3,715 366,338 SH   DFND 2 111,503 0 254,835
LivePerson Inc COM 538146101   1,257 123,932 SH   DFND 3 123,932 0 0
LivePerson Inc COM 538146101   2,514 247,880 SH   SOLE 0 247,880 0 0
Liveramp Holdings Inc COM 53815P108   14,425 615,401 SH   DFND 1 615,401 0 0
Liveramp Holdings Inc COM 53815P108   9,133 389,612 SH   DFND 2 121,405 0 268,207
Liveramp Holdings Inc COM 53815P108   3,976 169,628 SH   DFND 3 169,628 0 0
Liveramp Holdings Inc COM 53815P108   6,917 295,075 SH   SOLE 0 295,075 0 0
Logitech International SA SHS H50430232   14 235 SH   DFND 3 235 0 0
Lufax Holding Ltd COM 54975P102   11,485 5,919,894 SH   DFND 1 5,919,894 0 0
Lufax Holding Ltd COM 54975P102   37,570 19,365,754 SH   DFND 2 12,188,379 0 7,177,375
Lufax Holding Ltd COM 54975P102   304 156,806 SH   DFND 3 156,806 0 0
Lyell Immunopharma Inc COM 55083R104   459 132,192 SH   DFND 1 132,192 0 0
Lyell Immunopharma Inc COM 55083R104   1,036 298,630 SH   DFND 2 298,630 0 0
Lyell Immunopharma Inc COM 55083R104   1,147 330,499 SH   DFND 3 330,499 0 0
Lyft Inc Class A Common CL A COM 55087P104   12 1,088 SH   DFND 3 1,088 0 0
M&T Bank Corp COM 55261F104   7,210 49,707 SH   DFND 2 49,707 0 0
M&T Bank Corp COM 55261F104   21 144 SH   DFND 3 144 0 0
M&T Bank Corp COM 55261F104   3,246 22,377 SH   SOLE 0 22,377 0 0
MELI Kaszek Pioneer CL A COM G5S74L106   19,940 2,000,000 SH   DFND 2 2,000,000 0 0
MP Materials COM CL A 553368101   35,888 1,478,072 SH   DFND 1 1,478,072 0 0
MP Materials COM CL A 553368101   2,588 106,600 SH   DFND 3 106,600 0 0
MakeMyTrip SHS V5633W109   69,417 2,517,854 SH   DFND 2 1,903,125 0 614,729
Marathon Digital Holdings COM 565788106   1 200 SH   DFND 3 200 0 0
Markel Corp COM 570535104   52,112 39,554 SH   DFND 1 39,554 0 0
Markel Corp COM 570535104   178,320 135,348 SH   DFND 2 121,869 0 13,479
Markel Corp COM 570535104   37,717 28,628 SH   DFND 3 16,837 0 11,791
Markel Corp COM 570535104   193,044 146,524 SH   SOLE 0 99,925 0 46,599
MarketAxess Holdings COM 57060D108   129,811 465,455 SH   DFND 1 465,455 0 0
MarketAxess Holdings COM 57060D108   189,432 679,237 SH   DFND 2 540,599 0 138,638
MarketAxess Holdings COM 57060D108   25,520 91,507 SH   DFND 3 83,320 0 8,187
MarketAxess Holdings COM 57060D108   53,297 191,104 SH   SOLE 0 191,104 0 0
Marriott International CL A 571903202   15 100 SH   DFND 3 100 0 0
Martin Marietta Materials COM 573284106   139,046 411,415 SH   DFND 1 411,415 0 0
Martin Marietta Materials COM 573284106   492,003 1,455,759 SH   DFND 2 1,309,234 0 146,525
Martin Marietta Materials COM 573284106   91,421 270,500 SH   DFND 3 155,549 0 114,951
Martin Marietta Materials COM 573284106   341,579 1,010,677 SH   SOLE 0 733,549 0 277,128
Masimo Corp COM 574795100   2,502 16,914 SH   DFND 1 16,914 0 0
Masimo Corp COM 574795100   5,349 36,154 SH   DFND 2 36,154 0 0
Masimo Corp COM 574795100   6,372 43,067 SH   DFND 3 43,067 0 0
Mastercard Inc-Class A CL A 57636Q104   108,768 312,794 SH   DFND 1 312,794 0 0
Mastercard Inc-Class A CL A 57636Q104   363,549 1,045,492 SH   DFND 2 940,002 0 105,490
Mastercard Inc-Class A CL A 57636Q104   76,782 220,808 SH   DFND 3 129,207 0 91,601
Mastercard Inc-Class A CL A 57636Q104   372,138 1,070,193 SH   SOLE 0 694,525 0 375,668
Materialise Nv ADR SPONSORED ADS 57667T100   2,358 268,000 SH   DFND 2 268,000 0 0
Mativ Inc COM 808541106   6 265 SH   DFND 3 265 0 0
MaxCyte COM 57777K106   1,544 293,325 SH   DFND 1 293,325 0 0
Maxlinear Inc COM 57776J100   14 405 SH   DFND 3 405 0 0
McDonald's COM 580135101   16,438 62,376 SH   DFND 1 62,376 0 0
McDonald's COM 580135101   323 1,226 SH   DFND 2 0 0 1,226
McDonald's COM 580135101   741 2,813 SH   DFND 3 2,813 0 0
McDonald's COM 580135101   22,354 84,827 SH   SOLE 0 84,827 0 0
Medifast Inc COM 58470H101   16 138 SH   DFND 3 138 0 0
Medtronic COM G5960L103   19,146 246,346 SH   DFND 1 246,346 0 0
Medtronic COM G5960L103   170 2,188 SH   DFND 2 0 0 2,188
Medtronic COM G5960L103   3,150 40,531 SH   DFND 3 40,531 0 0
Medtronic COM G5960L103   11,392 146,580 SH   SOLE 0 146,580 0 0
MercadoLibre COM 58733R102   350,531 414,222 SH   DFND 1 414,222 0 0
MercadoLibre COM 58733R102   3,893,615 4,601,077 SH   DFND 2 3,558,829 0 1,042,248
MercadoLibre COM 58733R102   251,645 297,368 SH   DFND 3 233,274 0 64,094
MercadoLibre COM 58733R102   7,297 8,623 SH   DFND 4 8,623 0 0
MercadoLibre COM 58733R102   680,385 804,010 SH   SOLE 0 695,859 0 108,151
Merck COM 58933Y105   16 148 SH   DFND 3 148 0 0
Meta Platforms Inc CL A 30303M102   32,459 269,730 SH   DFND 1 269,730 0 0
Meta Platforms Inc CL A 30303M102   112,575 935,474 SH   DFND 2 842,692 0 92,782
Meta Platforms Inc CL A 30303M102   23,783 197,630 SH   DFND 3 116,184 0 81,446
Meta Platforms Inc CL A 30303M102   115,004 955,663 SH   SOLE 0 628,835 0 326,828
Mettler-Toledo COM 592688105   84,884 58,725 SH   DFND 1 58,725 0 0
Mettler-Toledo COM 592688105   343,105 237,369 SH   DFND 2 175,181 0 62,188
Mettler-Toledo COM 592688105   5,220 3,611 SH   DFND 3 2,392 0 1,219
Mettler-Toledo COM 592688105   37,599 26,012 SH   SOLE 0 26,012 0 0
Microsoft COM 594918104   211,232 880,796 SH   DFND 1 880,796 0 0
Microsoft COM 594918104   526,584 2,195,745 SH   DFND 2 1,989,533 0 206,212
Microsoft COM 594918104   118,897 495,776 SH   DFND 3 310,566 0 185,210
Microsoft COM 594918104   564,329 2,353,134 SH   SOLE 0 1,584,166 0 768,968
Mirati Therapeutics COM 60468T105   10 214 SH   DFND 3 214 0 0
Mobileye Global Inc. ORD SHS 60741F104   216,754 6,182,361 SH   DFND 2 5,236,386 0 945,975
Moderna Inc COM 60770K107   802,245 4,466,343 SH   DFND 1 4,466,343 0 0
Moderna Inc COM 60770K107   4,321,204 24,057,476 SH   DFND 2 18,961,374 0 5,096,102
Moderna Inc COM 60770K107   505,644 2,815,079 SH   DFND 3 2,293,626 0 521,453
Moderna Inc COM 60770K107   2,415,502 13,447,848 SH   SOLE 0 11,674,883 0 1,772,965
Momentive Global Inc COM 60878Y108   8 1,095 SH   DFND 3 1,095 0 0
MongoDB Inc COM 60937P106   46 235 SH   DFND 3 235 0 0
MongoDB Inc COM 60937P106   668 3,393 SH   SOLE 0 3,393 0 0
Monolithic Power Systems Inc COM 609839105   21 59 SH   DFND 3 59 0 0
Moody's Corp COM 615369105   143,686 515,707 SH   DFND 1 515,707 0 0
Moody's Corp COM 615369105   488,445 1,753,087 SH   DFND 2 1,580,217 0 172,870
Moody's Corp COM 615369105   105,364 378,163 SH   DFND 3 221,161 0 157,002
Moody's Corp COM 615369105   501,730 1,800,767 SH   SOLE 0 1,149,230 0 651,537
NIO Inc ADR SPON ADS 62914V106   29,510 3,026,698 SH   DFND 1 3,026,698 0 0
NIO Inc ADR SPON ADS 62914V106   810,659 83,144,563 SH   DFND 2 62,743,358 0 20,401,205
NIO Inc ADR SPON ADS 62914V106   45,254 4,641,427 SH   DFND 3 3,861,656 0 779,771
NIO Inc ADR SPON ADS 62914V106   294,902 30,246,387 SH   SOLE 0 25,855,423 0 4,390,964
NVIDIA COM 67066G104   264,643 1,810,885 SH   DFND 1 1,810,885 0 0
NVIDIA COM 67066G104   1,503,563 10,288,510 SH   DFND 2 6,393,869 0 3,894,641
NVIDIA COM 67066G104   191,303 1,309,039 SH   DFND 3 1,107,562 0 201,477
NVIDIA COM 67066G104   579,855 3,967,803 SH   SOLE 0 2,883,791 0 1,084,012
Nano Dimension ADR SPONS ADS 63008G203   4 1,600 SH   DFND 3 1,600 0 0
Nanobiotix ADR COM 63009J107   2,808 850,841 SH   DFND 1 850,841 0 0
Nanobiotix ADR COM 63009J107   1,812 549,159 SH   SOLE 0 549,159 0 0
National Instruments Corp COM 636518102   30,397 823,778 SH   DFND 1 823,778 0 0
National Instruments Corp COM 636518102   255 6,924 SH   DFND 2 0 0 6,924
National Instruments Corp COM 636518102   5,381 145,836 SH   DFND 3 145,836 0 0
National Instruments Corp COM 636518102   17,664 478,687 SH   SOLE 0 478,687 0 0
Nektar Therapeutics COM 640268108   3 1,376 SH   DFND 3 1,376 0 0
NetEase.com ADR SPONSORED ADR 64110W102   7,506 103,340 SH   DFND 2 0 0 103,340
Netflix Inc COM 64110L106   287,997 976,657 SH   DFND 1 976,657 0 0
Netflix Inc COM 64110L106   1,031,159 3,496,878 SH   DFND 2 2,109,399 0 1,387,479
Netflix Inc COM 64110L106   162,282 550,333 SH   DFND 3 450,580 0 99,753
Netflix Inc COM 64110L106   568,101 1,926,550 SH   SOLE 0 1,420,813 0 505,737
Nevro Corp COM 64157F103   6 154 SH   DFND 3 154 0 0
New Relic COM 64829B100   41 733 SH   DFND 3 733 0 0
Newmont Mining COM 651639106   1,225 25,959 SH   DFND 1 25,959 0 0
NextEra Energy COM 65339F101   7,024 84,023 SH   DFND 1 84,023 0 0
NextEra Energy COM 65339F101   928 11,103 SH   DFND 3 11,103 0 0
Nike COM 654106103   11 90 SH   DFND 3 90 0 0
Novanta Inc COM 67000B104   84 616 SH   DFND 2 616 0 0
Novanta Inc COM 67000B104   995 7,322 SH   DFND 3 7,322 0 0
Novavax Inc COM NEW 670002401   1 130 SH   DFND 3 130 0 0
Novocure Ltd ORD SHS G6674U108   175,566 2,393,540 SH   DFND 1 2,393,540 0 0
Novocure Ltd ORD SHS G6674U108   284,034 3,872,308 SH   DFND 2 3,399,723 0 472,585
Novocure Ltd ORD SHS G6674U108   44,497 606,635 SH   DFND 3 497,467 0 109,168
Novocure Ltd ORD SHS G6674U108   146,066 1,991,359 SH   SOLE 0 1,528,297 0 463,062
Nu Holdings Ltd. ORD SHS CL A G6683N103   53,238 13,080,561 SH   DFND 1 13,080,561 0 0
Nu Holdings Ltd. ORD SHS CL A G6683N103   315,615 77,546,642 SH   DFND 2 65,958,733 0 11,587,909
Nu Holdings Ltd. ORD SHS CL A G6683N103   84,714 20,814,269 SH   DFND 3 10,177,331 0 10,636,938
Nu Holdings Ltd. ORD SHS CL A G6683N103   13,054 3,207,382 SH   SOLE 0 1,201,697 0 2,005,685
Nucana Plc ADR SPONSORED ADR 67022C106   1,597 2,420,041 SH   DFND 1 2,420,041 0 0
Nucana Plc ADR SPONSORED ADR 67022C106   818 1,238,989 SH   SOLE 0 1,238,989 0 0
Nutanix Inc COM 67059N108   17 637 SH   DFND 3 637 0 0
Oatly Inc. SPONS ADS 67421J108   64,112 36,846,158 SH   DFND 2 30,631,807 0 6,214,351
On Semiconductor Corp COM 682189105   34 548 SH   DFND 3 548 0 0
OpenDoor Technologies COM 683712103   8 7,200 SH   SOLE 0 7,200 0 0
Opko Health Inc COM 68375N103   8 6,635 SH   DFND 3 6,635 0 0
Oscar Health Inc COM 687793109   113 46,097 SH   DFND 1 46,097 0 0
Oscar Health Inc COM 687793109   274 111,574 SH   DFND 2 111,574 0 0
Oscar Health Inc COM 687793109   296 120,320 SH   DFND 3 120,320 0 0
Oscar Health Inc COM 687793109   2,022 822,088 SH   SOLE 0 822,088 0 0
Outset Medical COM 690145107   8 306 SH   DFND 3 306 0 0
Oxford Industries Inc COM 691497309   5 55 SH   DFND 3 55 0 0
Ozon Holdings ADR COM 69269L104   0 333,970 SH   DFND 1 333,970 0 0
Ozon Holdings ADR COM 69269L104   0 2,478,153 SH   DFND 2 1,319,308 0 1,158,845
Ozon Holdings ADR COM 69269L104   0 19,278 SH   DFND 3 19,278 0 0
PROCEPT BioRobotics COM 74276L105   16 376 SH   DFND 3 376 0 0
Pacira BioSciences COM 695127100   27,735 718,329 SH   DFND 1 718,329 0 0
Pacira BioSciences COM 695127100   21,900 567,207 SH   DFND 2 174,025 0 393,182
Pacira BioSciences COM 695127100   10,471 271,198 SH   DFND 3 232,025 0 39,173
Pacira BioSciences COM 695127100   11,969 310,007 SH   SOLE 0 310,007 0 0
PagerDuty COM 69553P100   15 565 SH   DFND 3 565 0 0
Paychex COM 704326107   13 116 SH   DFND 3 116 0 0
Peloton Interactive Inc CL A COM 70614W100   5,439 684,988 SH   DFND 1 684,988 0 0
Peloton Interactive Inc CL A COM 70614W100   3,519 443,255 SH   DFND 2 273,529 0 169,726
Peloton Interactive Inc CL A COM 70614W100   5,619 707,643 SH   DFND 3 568,841 0 138,802
Peloton Interactive Inc CL A COM 70614W100   1,351 170,136 SH   SOLE 0 64,753 0 105,383
Penumbra Inc COM 70975L107   103,182 463,821 SH   DFND 1 463,821 0 0
Penumbra Inc COM 70975L107   148,558 667,796 SH   DFND 2 661,257 0 6,539
Penumbra Inc COM 70975L107   5,428 24,401 SH   DFND 3 24,401 0 0
Penumbra Inc COM 70975L107   23,534 105,790 SH   SOLE 0 105,790 0 0
Pepsico COM 713448108   65,874 364,631 SH   DFND 1 364,631 0 0
Pepsico COM 713448108   555 3,070 SH   DFND 2 0 0 3,070
Pepsico COM 713448108   11,933 66,055 SH   DFND 3 66,055 0 0
Pepsico COM 713448108   37,315 206,550 SH   SOLE 0 206,550 0 0
Petrobras Common ADR SPONSORED ADR 71654V408   128,326 12,049,410 SH   DFND 1 12,049,410 0 0
Petrobras Common ADR SPONSORED ADR 71654V408   461,815 43,362,956 SH   DFND 2 22,085,173 0 21,277,783
Petrobras Common ADR SPONSORED ADR 71654V408   25,254 2,371,244 SH   DFND 3 1,510,082 0 861,162
Petrobras Common ADR SPONSORED ADR 71654V408   7,399 694,728 SH   DFND 4 694,728 0 0
Petrobras Common ADR SPONSORED ADR 71654V408   6,726 631,579 SH   SOLE 0 631,579 0 0
Petrobras Pref ADR SP ADR NON VTG 71654V101   12,748 1,372,181 SH   DFND 1 1,372,181 0 0
Petrobras Pref ADR SP ADR NON VTG 71654V101   82,617 8,893,157 SH   DFND 2 6,578,822 0 2,314,335
Petrobras Pref ADR SP ADR NON VTG 71654V101   615 66,221 SH   DFND 3 66,221 0 0
Pfizer COM 717081103   24 466 SH   DFND 3 466 0 0
Physicians Realty Trust COM 71943U104   489 33,817 SH   DFND 1 33,817 0 0
Piedmont Lithium Inc COM 72016P105   11 251 SH   DFND 3 251 0 0
Pinduoduo Inc ADR SPONSORED ADS 722304102   128,094 1,570,739 SH   DFND 1 1,570,739 0 0
Pinduoduo Inc ADR SPONSORED ADS 722304102   1,319,636 16,181,923 SH   DFND 2 8,763,950 0 7,417,973
Pinduoduo Inc ADR SPONSORED ADS 722304102   199,652 2,448,217 SH   DFND 3 2,071,328 0 376,889
Pinduoduo Inc ADR SPONSORED ADS 722304102   687,067 8,425,101 SH   SOLE 0 6,305,232 0 2,119,869
Pinterest COM 72352L106   61,811 2,545,743 SH   DFND 1 2,545,743 0 0
Pinterest COM 72352L106   96,994 3,994,826 SH   DFND 2 3,956,094 0 38,732
Pinterest COM 72352L106   3,391 139,666 SH   DFND 3 139,666 0 0
Pinterest COM 72352L106   15,320 630,962 SH   SOLE 0 630,962 0 0
Precision BioSciences Inc COM 74019P108   6 4,774 SH   DFND 2 4,774 0 0
Precision BioSciences Inc COM 74019P108   67 56,678 SH   DFND 3 56,678 0 0
Procter & Gamble COM 742718109   72,717 479,790 SH   DFND 1 479,790 0 0
Procter & Gamble COM 742718109   614 4,054 SH   DFND 2 0 0 4,054
Procter & Gamble COM 742718109   13,124 86,596 SH   DFND 3 86,596 0 0
Procter & Gamble COM 742718109   40,916 269,966 SH   SOLE 0 269,966 0 0
Progressive COM 743315103   8,406 64,808 SH   DFND 2 64,808 0 0
Progressive COM 743315103   26 202 SH   DFND 3 202 0 0
Progressive COM 743315103   3,869 29,825 SH   SOLE 0 29,825 0 0
Progyny COM 74340E103   19,255 618,143 SH   DFND 1 618,143 0 0
Progyny COM 74340E103   16,860 541,241 SH   DFND 2 164,391 0 376,850
Progyny COM 74340E103   7,229 232,058 SH   DFND 3 206,150 0 25,908
Progyny COM 74340E103   7,208 231,385 SH   SOLE 0 231,385 0 0
Prologis Inc REIT COM 74340W103   33,121 293,808 SH   DFND 1 293,808 0 0
Prologis Inc REIT COM 74340W103   3,581 31,764 SH   DFND 3 31,764 0 0
Proterra Inc COM 74374T109   47 12,406 SH   DFND 1 12,406 0 0
Ptc Therapeutics Inc COM 69366J200   9 246 SH   DFND 3 246 0 0
Pure Storage Inc COM 74624M102   36 1,335 SH   DFND 3 1,335 0 0
Q2 Holdings Inc COM 74736L109   4,251 158,209 SH   DFND 1 158,209 0 0
Q2 Holdings Inc COM 74736L109   4,902 182,434 SH   DFND 2 56,733 0 125,701
Q2 Holdings Inc COM 74736L109   2,139 79,620 SH   DFND 3 79,620 0 0
Q2 Holdings Inc COM 74736L109   3,284 122,235 SH   SOLE 0 122,235 0 0
Qualcomm COM 747525103   20 183 SH   DFND 3 183 0 0
Quanterix Corp COM 74766Q101   5,417 391,135 SH   DFND 1 391,135 0 0
Quanterix Corp COM 74766Q101   33 2,370 SH   DFND 2 2,370 0 0
Quanterix Corp COM 74766Q101   402 29,013 SH   DFND 3 29,013 0 0
Quanterix Corp COM 74766Q101   2,904 209,677 SH   SOLE 0 209,677 0 0
QuantumScape Corp COM CL A 74767V109   1,980 349,250 SH   DFND 1 349,250 0 0
QuantumScape Corp COM CL A 74767V109   5,178 913,279 SH   SOLE 0 913,279 0 0
Quest Diagnostics COM 74834L100   23 145 SH   DFND 3 145 0 0
Quidel Corp COM 219798105   11 128 SH   DFND 3 128 0 0
REGENXBIO COM 75901B107   17 752 SH   DFND 3 752 0 0
Rambus Inc COM 750917106   23 630 SH   DFND 3 630 0 0
Recursion Pharmaceuticals Inc CL A 75629V104   23,598 3,060,653 SH   DFND 1 3,060,653 0 0
Recursion Pharmaceuticals Inc CL A 75629V104   34,286 4,446,893 SH   DFND 2 4,405,504 0 41,389
Recursion Pharmaceuticals Inc CL A 75629V104   4,400 570,707 SH   DFND 3 570,707 0 0
Recursion Pharmaceuticals Inc CL A 75629V104   129,085 16,742,597 SH   SOLE 0 16,742,597 0 0
Redfin COM 75737F108   15,284 3,604,813 SH   DFND 1 3,604,813 0 0
Redfin COM 75737F108   21,653 5,106,917 SH   DFND 2 4,969,813 0 137,104
Redfin COM 75737F108   1,278 301,440 SH   DFND 3 264,255 0 37,185
Redfin COM 75737F108   3,156 744,408 SH   SOLE 0 744,408 0 0
Regeneron Pharmaceuticals COM 75886F107   34 47 SH   DFND 3 47 0 0
Relay Therapeutics Inc COM 75943R102   1,079 72,201 SH   DFND 1 72,201 0 0
Relay Therapeutics Inc COM 75943R102   2,395 160,294 SH   DFND 2 160,294 0 0
Relay Therapeutics Inc COM 75943R102   2,719 182,027 SH   DFND 3 182,027 0 0
Remitly Global Inc COM 75960P104   6,912 603,641 SH   DFND 1 603,641 0 0
Remitly Global Inc COM 75960P104   4,133 360,945 SH   DFND 2 217,689 0 143,256
Remitly Global Inc COM 75960P104   6,646 580,459 SH   DFND 3 469,461 0 110,998
Remitly Global Inc COM 75960P104   2,213 193,289 SH   SOLE 0 99,386 0 93,903
ResMed COM 761152107   2,458 11,811 SH   DFND 1 11,811 0 0
ResMed COM 761152107   5,315 25,537 SH   DFND 2 25,537 0 0
ResMed COM 761152107   6,262 30,085 SH   DFND 3 30,085 0 0
Research in Motion COM 09228F103   8 2,434 SH   DFND 3 2,434 0 0
Rexford Industrial Realty REIT COM 76169C100   39,042 714,528 SH   DFND 1 714,528 0 0
Rexford Industrial Realty REIT COM 76169C100   4,504 82,434 SH   DFND 3 82,434 0 0
Rio Tinto Spn.Adr 1:1 SPONSORED ADR 767204100   7 92 SH   DFND 4 92 0 0
Ritchie Bros Auctioneers (USA) COM 767744105   51,624 892,690 SH   DFND 2 813,219 0 79,471
Ritchie Bros Auctioneers (USA) COM 767744105   2 32 SH   DFND 4 32 0 0
Ritchie Bros. Auctioneers COM 767744105   40,289 697,994 SH   DFND 2 422,569 0 275,425
Rivian Automotive Inc COM CL A 76954A103   21,134 1,146,692 SH   DFND 1 1,146,692 0 0
Rivian Automotive Inc COM CL A 76954A103   33,196 1,801,220 SH   DFND 2 1,783,601 0 17,619
Rivian Automotive Inc COM CL A 76954A103   1,121 60,837 SH   DFND 3 60,837 0 0
Rivian Automotive Inc COM CL A 76954A103   5,490 297,878 SH   SOLE 0 297,878 0 0
Robert Half International Inc COM 770323103   10 131 SH   DFND 3 131 0 0
Roblox CL A 771049103   117,241 4,119,501 SH   DFND 1 4,119,501 0 0
Roblox CL A 771049103   442,558 15,550,163 SH   DFND 2 9,042,894 0 6,507,269
Roblox CL A 771049103   64,644 2,271,393 SH   DFND 3 1,928,293 0 343,100
Roblox CL A 771049103   213,504 7,501,900 SH   SOLE 0 5,568,759 0 1,933,141
Roku COM CL A 77543R102   49,946 1,227,166 SH   DFND 1 1,227,166 0 0
Roku COM CL A 77543R102   74,673 1,834,707 SH   DFND 2 1,816,714 0 17,993
Roku COM CL A 77543R102   2,607 64,059 SH   DFND 3 64,059 0 0
Roku COM CL A 77543R102   11,378 279,568 SH   SOLE 0 279,568 0 0
Rollins Inc COM 775711104   21 562 SH   DFND 3 562 0 0
Royalty Pharma SHS CLASS A G7709Q104   78,353 1,982,604 SH   DFND 1 1,982,604 0 0
Royalty Pharma SHS CLASS A G7709Q104   266,685 6,748,105 SH   DFND 2 6,076,507 0 671,598
Royalty Pharma SHS CLASS A G7709Q104   56,542 1,430,729 SH   DFND 3 836,333 0 594,396
Royalty Pharma SHS CLASS A G7709Q104   274,974 6,957,844 SH   SOLE 0 4,668,322 0 2,289,522
Rubius Therapeutics Inc COM 78116T103   153 887,000 SH   DFND 1 887,000 0 0
Rubius Therapeutics Inc COM 78116T103   42 243,845 SH   DFND 2 69,451 0 174,394
Rubius Therapeutics Inc COM 78116T103   26 152,722 SH   DFND 3 152,722 0 0
Rubius Therapeutics Inc COM 78116T103   617 3,585,559 SH   SOLE 0 3,585,559 0 0
Ryanair ADR SPONSORED ADR NE 783513203   21,635 289,398 SH   DFND 1 289,398 0 0
Ryanair ADR SPONSORED ADR NE 783513203   625,405 8,365,508 SH   DFND 2 7,220,796 0 1,144,712
Ryanair ADR SPONSORED ADR NE 783513203   7,051 94,318 SH   DFND 3 94,318 0 0
Ryanair ADR SPONSORED ADR NE 783513203   7 89 SH   DFND 4 89 0 0
Ryanair ADR SPONSORED ADR NE 783513203   9,573 128,046 SH   SOLE 0 120,991 0 7,055
S&P Global Inc COM 78409V104   58,448 174,503 SH   DFND 1 174,503 0 0
S&P Global Inc COM 78409V104   210,362 628,059 SH   DFND 2 567,704 0 60,355
S&P Global Inc COM 78409V104   43,346 129,414 SH   DFND 3 75,318 0 54,096
S&P Global Inc COM 78409V104   211,951 632,802 SH   SOLE 0 415,322 0 217,480
SCP Pool Corporation COM 73278L105   21 70 SH   DFND 3 70 0 0
SEA Ltd ADR ADR 81141R100   143,705 2,761,971 SH   DFND 1 2,761,971 0 0
SEA Ltd ADR ADR 81141R100   658,433 12,654,866 SH   DFND 2 8,598,542 0 4,056,324
SEA Ltd ADR ADR 81141R100   67,357 1,294,572 SH   DFND 3 957,036 0 337,536
SEA Ltd ADR ADR 81141R100   1,680 32,296 SH   DFND 4 32,296 0 0
SEA Ltd ADR ADR 81141R100   182,662 3,510,705 SH   SOLE 0 2,110,258 0 1,400,447
SKYWORKS SOLUTIONS, INC. COM 83088M102   12 136 SH   DFND 3 136 0 0
Sage Therapeutics Inc COM 78667J108   630 16,510 SH   DFND 1 16,510 0 0
Sage Therapeutics Inc COM 78667J108   1,388 36,403 SH   DFND 2 36,403 0 0
Sage Therapeutics Inc COM 78667J108   1,601 41,972 SH   DFND 3 41,972 0 0
Salesforce.com COM 79466L302   33,236 250,669 SH   DFND 1 250,669 0 0
Salesforce.com COM 79466L302   270,966 2,043,642 SH   DFND 2 848,268 0 1,195,374
Salesforce.com COM 79466L302   51,066 385,140 SH   DFND 3 321,662 0 63,478
Salesforce.com COM 79466L302   83,938 633,066 SH   SOLE 0 276,825 0 356,241
Sana Biotechnology Inc COM 799566104   6,425 1,626,648 SH   DFND 1 1,626,648 0 0
Sana Biotechnology Inc COM 799566104   10,943 2,770,338 SH   DFND 2 2,770,338 0 0
Sana Biotechnology Inc COM 799566104   631 159,846 SH   DFND 3 159,846 0 0
Sana Biotechnology Inc COM 799566104   24,521 6,207,895 SH   SOLE 0 6,207,895 0 0
Sangamo Biosciences COM 800677106   8 2,510 SH   DFND 3 2,510 0 0
Sarepta Therapeutics Inc COM 803607100   26 199 SH   DFND 3 199 0 0
Schrodinger COM 80810D103   9,600 513,642 SH   DFND 1 513,642 0 0
Schrodinger COM 80810D103   11,040 590,673 SH   DFND 2 181,159 0 409,514
Schrodinger COM 80810D103   4,169 223,038 SH   DFND 3 223,038 0 0
Schrodinger COM 80810D103   9,242 494,505 SH   SOLE 0 494,505 0 0
Seagen Inc COM 81181C104   16 128 SH   DFND 3 128 0 0
Seer COM CL A 81578P106   1 223 SH   DFND 3 223 0 0
Sei Investments Co COM 784117103   27 471 SH   DFND 3 471 0 0
Service Corp.Intl. COM 817565104   131,039 1,895,264 SH   DFND 1 1,895,264 0 0
Service Corp.Intl. COM 817565104   451,980 6,537,172 SH   DFND 2 5,890,451 0 646,721
Service Corp.Intl. COM 817565104   95,288 1,378,192 SH   DFND 3 802,292 0 575,900
Service Corp.Intl. COM 817565104   452,357 6,542,618 SH   SOLE 0 4,334,865 0 2,207,753
Sherwin-Williams Co COM 824348106   10,133 42,694 SH   DFND 2 42,694 0 0
ShockWave Medical Inc COM 82489T104   11,339 55,148 SH   DFND 1 55,148 0 0
ShockWave Medical Inc COM 82489T104   30,078 146,289 SH   DFND 2 93,414 0 52,875
ShockWave Medical Inc COM 82489T104   19,095 92,869 SH   DFND 3 92,869 0 0
ShockWave Medical Inc COM 82489T104   11,017 53,584 SH   SOLE 0 53,584 0 0
Shopify 'A' CL A 82509L107   499,119 14,379,697 SH   DFND 1 14,379,697 0 0
Shopify 'A' CL A 82509L107   1,336,540 38,505,897 SH   DFND 2 26,540,679 0 11,965,218
Shopify 'A' CL A 82509L107   230,617 6,644,104 SH   DFND 3 5,326,742 0 1,317,362
Shopify 'A' CL A 82509L107   2 65 SH   DFND 4 65 0 0
Shopify 'A' CL A 82509L107   444,058 12,793,375 SH   SOLE 0 8,891,096 0 3,902,279
Shopify Inc COM 82509L107   4,263 122,868 SH   DFND 2 122,868 0 0
Shopify Inc COM 82509L107   68 1,955 SH   DFND 3 1,955 0 0
Signature Bank COM 82669G104   4,199 36,446 SH   DFND 2 36,446 0 0
Signature Bank COM 82669G104   7 63 SH   DFND 3 63 0 0
Signature Bank COM 82669G104   1,152 10,002 SH   SOLE 0 10,002 0 0
Silicon Motion Technology ADR COM 82706C108   15,224 234,246 SH   DFND 1 234,246 0 0
Silicon Motion Technology ADR COM 82706C108   138 2,123 SH   DFND 2 0 0 2,123
Silicon Motion Technology ADR COM 82706C108   2,318 35,672 SH   DFND 3 35,672 0 0
Silicon Motion Technology ADR COM 82706C108   9,245 142,259 SH   SOLE 0 142,259 0 0
Silk Road Medical COM 82710M100   12 235 SH   DFND 3 235 0 0
SiteOne Landscape Supply COM 82982L103   34,348 292,774 SH   DFND 1 292,774 0 0
SiteOne Landscape Supply COM 82982L103   112,172 956,118 SH   DFND 2 856,701 0 99,417
SiteOne Landscape Supply COM 82982L103   25,168 214,521 SH   DFND 3 126,040 0 88,481
SiteOne Landscape Supply COM 82982L103   118,008 1,005,861 SH   SOLE 0 657,694 0 348,167
Sixth Street Specialty Lending COM 83012A109   1,415 79,500 SH   DFND 1 79,500 0 0
Smartsheet COM 83200N103   14 352 SH   DFND 3 352 0 0
Snap Inc CL A 83304A106   34,533 3,858,433 SH   DFND 1 3,858,433 0 0
Snap Inc CL A 83304A106   52,862 5,906,350 SH   DFND 2 5,848,473 0 57,877
Snap Inc CL A 83304A106   1,802 201,335 SH   DFND 3 201,335 0 0
Snap Inc CL A 83304A106   10,054 1,123,309 SH   SOLE 0 1,123,309 0 0
Snap On COM 833034101   20 86 SH   DFND 3 86 0 0
Snowflake Inc COM 833445109   120,943 842,572 SH   DFND 1 842,572 0 0
Snowflake Inc COM 833445109   231,150 1,610,355 SH   DFND 2 1,546,197 0 64,158
Snowflake Inc COM 833445109   22,214 154,760 SH   DFND 3 105,495 0 49,265
Snowflake Inc COM 833445109   287,512 2,003,008 SH   SOLE 0 1,807,609 0 195,399
Solaredge Technologies Inc COM 83417M104   325 1,147 SH   DFND 1 1,147 0 0
Solaredge Technologies Inc COM 83417M104   2,595 9,161 SH   DFND 2 9,161 0 0
Solaredge Technologies Inc COM 83417M104   47 167 SH   DFND 3 167 0 0
Solaredge Technologies Inc COM 83417M104   7,738 27,317 SH   SOLE 0 0 0 27,317
Sorrento Therapeutics COM 83587F202   3 3,711 SH   DFND 3 3,711 0 0
Spire Global Inc COM CL A 848560108   831 866,045 SH   SOLE 0 866,045 0 0
Splunk Inc COM 848637104   4,816 55,940 SH   DFND 1 55,940 0 0
Splunk Inc COM 848637104   11,672 135,584 SH   DFND 2 40,330 0 95,254
Splunk Inc COM 848637104   3,977 46,191 SH   DFND 3 46,191 0 0
Splunk Inc COM 848637104   6,361 73,884 SH   SOLE 0 73,884 0 0
Spotify Technology SA SHS L8681T102   88,947 1,126,623 SH   DFND 1 1,126,623 0 0
Spotify Technology SA SHS L8681T102   1,768,250 22,397,089 SH   DFND 2 16,943,814 0 5,453,275
Spotify Technology SA SHS L8681T102   70,806 896,842 SH   DFND 3 717,143 0 179,699
Spotify Technology SA SHS L8681T102   2 20 SH   DFND 4 20 0 0
Spotify Technology SA SHS L8681T102   277,666 3,516,980 SH   SOLE 0 2,679,323 0 837,657
Sprout Social COM 85209W109   18,128 321,078 SH   DFND 1 321,078 0 0
Sprout Social COM 85209W109   17,253 305,580 SH   DFND 2 93,368 0 212,212
Sprout Social COM 85209W109   7,201 127,540 SH   DFND 3 127,540 0 0
Sprout Social COM 85209W109   13,882 245,870 SH   SOLE 0 245,870 0 0
Staar Surgical COM PAR $0.01 852312305   70,561 1,453,672 SH   DFND 1 1,453,672 0 0
Staar Surgical COM PAR $0.01 852312305   83,876 1,727,980 SH   DFND 2 1,110,705 0 617,275
Staar Surgical COM PAR $0.01 852312305   28,291 582,842 SH   DFND 3 471,743 0 111,099
Staar Surgical COM PAR $0.01 852312305   71,643 1,475,962 SH   SOLE 0 1,145,092 0 330,870
Starbucks Corp COM 855244109   36,617 369,119 SH   DFND 1 369,119 0 0
Starbucks Corp COM 855244109   21,535 217,089 SH   DFND 2 184,806 0 32,283
Starbucks Corp COM 855244109   8,049 81,143 SH   DFND 3 70,352 0 10,791
Starbucks Corp COM 855244109   19,436 195,927 SH   SOLE 0 195,927 0 0
Stitch Fix COM CL A 860897107   9 2,755 SH   DFND 2 2,755 0 0
Stitch Fix COM CL A 860897107   100 32,301 SH   DFND 3 32,301 0 0
StoneCo COM CL A G85158106   1,514 160,397 SH   DFND 1 160,397 0 0
StoneCo COM CL A G85158106   12,218 1,294,292 SH   DFND 2 702,457 0 591,835
StoneCo COM CL A G85158106   68 7,186 SH   DFND 3 7,186 0 0
Stratasys SHS M85548101   2,684 226,300 SH   DFND 1 226,300 0 0
Stratasys SHS M85548101   3,820 322,123 SH   DFND 2 100,241 0 221,882
Stratasys SHS M85548101   1,598 134,725 SH   DFND 3 134,725 0 0
Stratasys SHS M85548101   1,715 144,600 SH   SOLE 0 144,600 0 0
Sumo Logic COM 86646P103   6 726 SH   DFND 3 726 0 0
Sunpower Corp COM 867652406   22 1,210 SH   DFND 3 1,210 0 0
Sutro Biopharma COM 869367102   8,423 1,042,428 SH   DFND 1 1,042,428 0 0
Sutro Biopharma COM 869367102   48 5,929 SH   DFND 2 5,929 0 0
Sutro Biopharma COM 869367102   562 69,532 SH   DFND 3 69,532 0 0
Sutro Biopharma COM 869367102   6,066 750,726 SH   SOLE 0 750,726 0 0
Sweetgreen COM CL A 87043Q108   16,302 1,902,268 SH   DFND 1 1,902,268 0 0
Sweetgreen COM CL A 87043Q108   24,344 2,840,569 SH   DFND 2 2,812,954 0 27,615
Sweetgreen COM CL A 87043Q108   861 100,443 SH   DFND 3 100,443 0 0
Sweetgreen COM CL A 87043Q108   3,843 448,434 SH   SOLE 0 448,434 0 0
T. Rowe Price COM 74144T108   17,775 162,984 SH   DFND 1 162,984 0 0
T. Rowe Price COM 74144T108   149 1,366 SH   DFND 2 0 0 1,366
T. Rowe Price COM 74144T108   3,089 28,325 SH   DFND 3 28,325 0 0
T. Rowe Price COM 74144T108   10,111 92,715 SH   SOLE 0 92,715 0 0
TJX Companies COM 872540109   8,552 107,431 SH   DFND 2 107,431 0 0
TJX Companies COM 872540109   33 411 SH   DFND 3 411 0 0
TJX Companies COM 872540109   4,856 61,007 SH   SOLE 0 61,007 0 0
TSMC ADR SPONSORED ADR 874039100   503,250 6,755,944 SH   DFND 2 5,209,159 0 1,546,785
TSMC ADR SPONSORED ADR 874039100   64 863 SH   DFND 3 863 0 0
TSMC ADR SPONSORED ADR 874039100   9 119 SH   DFND 4 119 0 0
TSMC ADR SPONSORED ADR 874039100   49,579 665,573 SH   SOLE 0 539,809 0 125,764
Tabula Rasa HealthCare Inc COM 873379101   2,778 561,175 SH   DFND 1 561,175 0 0
Tabula Rasa HealthCare Inc COM 873379101   12 2,495 SH   DFND 2 2,495 0 0
Tabula Rasa HealthCare Inc COM 873379101   146 29,449 SH   DFND 3 29,449 0 0
Tabula Rasa HealthCare Inc COM 873379101   1,181 238,574 SH   SOLE 0 238,574 0 0
Tandem Diabetes Care COM NEW 875372203   4,632 103,043 SH   DFND 1 103,043 0 0
Tandem Diabetes Care COM NEW 875372203   40 892 SH   DFND 2 892 0 0
Tandem Diabetes Care COM NEW 875372203   484 10,772 SH   DFND 3 10,772 0 0
Tandem Diabetes Care COM NEW 875372203   6,670 148,377 SH   SOLE 0 148,377 0 0
Target Corp COM 87612E106   14 97 SH   DFND 3 97 0 0
Tata Motors Ltd ADR COM 876568502   48,906 2,116,218 SH   DFND 1 2,116,218 0 0
Tata Motors Ltd ADR COM 876568502   25,758 1,114,586 SH   DFND 2 1,114,586 0 0
Tata Motors Ltd ADR COM 876568502   798 34,531 SH   DFND 3 34,531 0 0
Tata Motors Ltd ADR COM 876568502   13,041 564,300 SH   SOLE 0 564,300 0 0
Teladoc COM 87918A105   40,514 1,713,051 SH   DFND 1 1,713,051 0 0
Teladoc COM 87918A105   27,795 1,175,284 SH   DFND 2 622,613 0 552,671
Teladoc COM 87918A105   30,925 1,307,617 SH   DFND 3 1,106,371 0 201,246
Teladoc COM 87918A105   13,037 551,259 SH   SOLE 0 389,449 0 161,810
Telus Corp COM 87971M103   10 497 SH   DFND 3 497 0 0
Tenable Holdings COM 88025T102   12 315 SH   DFND 3 315 0 0
Tencent ADR SPON ADR 88032Q109   5 108 SH   DFND 4 108 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109   8,055 972,779 SH   DFND 1 972,779 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109   235,772 28,474,864 SH   DFND 2 19,984,185 0 8,490,679
Tencent Music Entertainment ADR SPONSORED ADS 88034P109   395 47,707 SH   DFND 3 47,707 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109   3 393 SH   DFND 4 393 0 0
Teradyne COM 880770102   55,230 632,279 SH   DFND 1 632,279 0 0
Teradyne COM 880770102   181,923 2,082,685 SH   DFND 2 1,868,802 0 213,883
Teradyne COM 880770102   40,406 462,581 SH   DFND 3 273,639 0 188,942
Teradyne COM 880770102   188,522 2,158,238 SH   SOLE 0 1,392,633 0 765,605
Tesla Inc COM 88160R101   404,743 3,285,781 SH   DFND 1 3,285,781 0 0
Tesla Inc COM 88160R101   1,755,742 14,253,467 SH   DFND 2 10,379,231 0 3,874,236
Tesla Inc COM 88160R101   228,263 1,853,086 SH   DFND 3 1,496,484 0 356,602
Tesla Inc COM 88160R101   914,242 7,422,004 SH   SOLE 0 5,965,081 0 1,456,923
Texas Instruments COM 882508104   14,160 85,705 SH   DFND 1 85,705 0 0
Texas Instruments COM 882508104   14,084 85,242 SH   DFND 2 59,772 0 25,470
Texas Instruments COM 882508104   4,259 25,776 SH   DFND 3 16,655 0 9,121
Texas Instruments COM 882508104   4,526 27,395 SH   SOLE 0 27,395 0 0
Texas Roadhouse Inc COM 882681109   12 131 SH   DFND 3 131 0 0
The Trade Desk COM CL A 88339J105   428,850 9,566,138 SH   DFND 1 9,566,138 0 0
The Trade Desk COM CL A 88339J105   1,132,655 25,265,563 SH   DFND 2 17,861,432 0 7,404,131
The Trade Desk COM CL A 88339J105   156,419 3,489,170 SH   DFND 3 2,774,117 0 715,053
The Trade Desk COM CL A 88339J105   396,950 8,854,555 SH   SOLE 0 5,566,074 0 3,288,481
Thermo Fisher Scientific COM 883556102   79,897 145,086 SH   DFND 1 145,086 0 0
Thermo Fisher Scientific COM 883556102   280,840 509,978 SH   DFND 2 462,030 0 47,948
Thermo Fisher Scientific COM 883556102   56,725 103,008 SH   DFND 3 60,194 0 42,814
Thermo Fisher Scientific COM 883556102   285,710 518,822 SH   SOLE 0 347,475 0 171,347
Toro Co COM 891092108   29 259 SH   DFND 3 259 0 0
Tractor Supply Co COM 892356106   35 155 SH   DFND 3 155 0 0
TransMedics Group COM 89377M109   6,869 111,301 SH   DFND 1 111,301 0 0
TransMedics Group COM 89377M109   167 2,699 SH   DFND 2 2,699 0 0
TransMedics Group COM 89377M109   2,010 32,572 SH   DFND 3 32,572 0 0
TransMedics Group COM 89377M109   6,588 106,747 SH   SOLE 0 106,747 0 0
Trupanion COM 898202106   9,392 197,600 SH   DFND 1 197,600 0 0
Trupanion COM 898202106   15,616 328,546 SH   DFND 2 99,263 0 229,283
Trupanion COM 898202106   6,095 128,239 SH   DFND 3 128,239 0 0
Trupanion COM 898202106   18,115 381,138 SH   SOLE 0 381,138 0 0
TuSimple Hdgs CL A 90089L108   1 349 SH   DFND 3 349 0 0
Twilio Inc CL A 90138F102   92,202 1,883,216 SH   DFND 1 1,883,216 0 0
Twilio Inc CL A 90138F102   160,443 3,277,021 SH   DFND 2 3,130,701 0 146,320
Twilio Inc CL A 90138F102   15,029 306,969 SH   DFND 3 214,778 0 92,191
Twilio Inc CL A 90138F102   63,815 1,303,417 SH   SOLE 0 971,152 0 332,265
Twist Bioscience Corp COM 90184D100   6,974 292,900 SH   DFND 1 292,900 0 0
Twist Bioscience Corp COM 90184D100   8,972 376,801 SH   DFND 2 114,118 0 262,683
Twist Bioscience Corp COM 90184D100   3,402 142,878 SH   DFND 3 142,878 0 0
Twist Bioscience Corp COM 90184D100   6,500 273,000 SH   SOLE 0 273,000 0 0
Ultragenyx COM 90400D108   5 115 SH   DFND 3 115 0 0
United Parcel Service CL B 911312106   69,812 401,588 SH   DFND 1 401,588 0 0
United Parcel Service CL B 911312106   8,750 50,334 SH   DFND 2 46,836 0 3,498
United Parcel Service CL B 911312106   12,490 71,845 SH   DFND 3 71,845 0 0
United Parcel Service CL B 911312106   44,800 257,707 SH   SOLE 0 257,707 0 0
UnitedHealth COM 91324P102   36 67 SH   DFND 3 67 0 0
Upwork Inc COM 91688F104   27,740 2,657,090 SH   DFND 1 2,657,090 0 0
Upwork Inc COM 91688F104   20,594 1,972,588 SH   DFND 2 599,007 0 1,373,581
Upwork Inc COM 91688F104   8,722 835,439 SH   DFND 3 761,911 0 73,528
Upwork Inc COM 91688F104   14,010 1,341,907 SH   SOLE 0 1,341,907 0 0
Vale SA ADR ADR 91912E105   11 647 SH   DFND 2 647 0 0
Varonis Systems Inc COM 922280102   41 1,719 SH   DFND 2 1,719 0 0
Varonis Systems Inc COM 922280102   501 20,943 SH   DFND 3 20,943 0 0
Veeco Instruments COM 922417100   4,313 232,154 SH   DFND 1 232,154 0 0
Veeco Instruments COM 922417100   9,644 519,070 SH   DFND 2 156,187 0 362,883
Veeco Instruments COM 922417100   3,827 205,967 SH   DFND 3 205,967 0 0
Veeva Systems Inc Class A COM 922475108   1,206 7,470 SH   DFND 1 7,470 0 0
Veeva Systems Inc Class A COM 922475108   2,643 16,380 SH   DFND 2 16,380 0 0
Veeva Systems Inc Class A COM 922475108   3,074 19,048 SH   DFND 3 19,048 0 0
Verint Systems Inc COM 92343X100   14 395 SH   DFND 3 395 0 0
Veritone COM 92347M100   3 649 SH   DFND 3 649 0 0
Vir Biotechnology Inc COM 92764N102   807 31,880 SH   DFND 1 31,880 0 0
Vir Biotechnology Inc COM 92764N102   1,724 68,104 SH   DFND 2 68,104 0 0
Vir Biotechnology Inc COM 92764N102   2,093 82,709 SH   DFND 3 82,709 0 0
Vir Biotechnology Inc COM 92764N102   96,226 3,801,908 SH   SOLE 0 3,801,908 0 0
Visa Inc-Class A Shares COM CL A 92826C839   10,884 52,389 SH   DFND 2 52,389 0 0
Visa Inc-Class A Shares COM CL A 92826C839   23 110 SH   DFND 3 110 0 0
Visteon Corp COM 92839U206   29 218 SH   DFND 3 218 0 0
Vuzix COM 92921W300   3 924 SH   DFND 3 924 0 0
WD-40 Co COM 929236107   13 80 SH   DFND 3 80 0 0
WEC Energy Group COM 92939U106   1,064 11,353 SH   DFND 1 11,353 0 0
Wal-Mart Stores COM 931142103   18 126 SH   DFND 3 126 0 0
Warby Parker Inc CL A COM 93403J106   2,620 194,204 SH   DFND 1 194,204 0 0
Warby Parker Inc CL A COM 93403J106   7,418 549,882 SH   DFND 2 205,774 0 344,108
Warby Parker Inc CL A COM 93403J106   827 61,339 SH   DFND 3 40,209 0 21,130
Warby Parker Inc CL A COM 93403J106   73,886 5,477,124 SH   SOLE 0 5,477,124 0 0
Waters COM 941848103   10,003 29,198 SH   DFND 1 29,198 0 0
Waters COM 941848103   4,347 12,689 SH   DFND 2 4,022 0 8,667
Waters COM 941848103   3,079 8,989 SH   DFND 3 5,790 0 3,199
Waters COM 941848103   537 1,567 SH   SOLE 0 1,567 0 0
Watsco Inc COM 942622200   214,854 861,483 SH   DFND 1 861,483 0 0
Watsco Inc COM 942622200   238,052 954,497 SH   DFND 2 929,119 0 25,378
Watsco Inc COM 942622200   21,683 86,942 SH   DFND 3 81,613 0 5,329
Watsco Inc COM 942622200   69,368 278,138 SH   SOLE 0 278,138 0 0
Wayfair Inc Class A CL A 94419L101   68,594 2,085,559 SH   DFND 1 2,085,559 0 0
Wayfair Inc Class A CL A 94419L101   116,387 3,538,674 SH   DFND 2 3,344,541 0 194,133
Wayfair Inc Class A CL A 94419L101   10,308 313,421 SH   DFND 3 239,798 0 73,623
Wayfair Inc Class A CL A 94419L101   86,680 2,635,444 SH   SOLE 0 2,354,589 0 280,855
West Pharmaceutical Services COM 955306105   9 40 SH   DFND 3 40 0 0
Wheaton Precious Metals COM 962879102   798 20,416 SH   DFND 1 20,416 0 0
Williams-Sonoma Inc COM 969904101   7 63 SH   DFND 3 63 0 0
Wix Com SHS M98068105   618,186 8,046,154 SH   DFND 2 5,977,763 0 2,068,391
Wix Com SHS M98068105   31 406 SH   DFND 3 406 0 0
Workday Inc CL A 98138H101   210,320 1,256,917 SH   DFND 1 1,256,917 0 0
Workday Inc CL A 98138H101   721,199 4,310,041 SH   DFND 2 2,443,330 0 1,866,711
Workday Inc CL A 98138H101   109,937 657,005 SH   DFND 3 550,240 0 106,765
Workday Inc CL A 98138H101   194,586 1,162,885 SH   SOLE 0 619,172 0 543,713
XP CL A G98239109   824 53,729 SH   DFND 1 53,729 0 0
XP CL A G98239109   2,637 171,904 SH   DFND 2 12,129 0 159,775
XP CL A G98239109   2,659 173,349 SH   DFND 3 22,057 0 151,292
XP CL A G98239109   136 8,893 SH   DFND 4 8,893 0 0
XPEL COM 98379L100   20 326 SH   DFND 3 326 0 0
Xencor Inc COM 98401F105   64 2,452 SH   DFND 2 2,452 0 0
Xencor Inc COM 98401F105   771 29,603 SH   DFND 3 29,603 0 0
Xperi COM 98423J101   5 579 SH   DFND 3 579 0 0
Xylem COM 98419M100   122,193 1,105,121 SH   DFND 1 1,105,121 0 0
Xylem COM 98419M100   74,481 673,612 SH   DFND 2 408,232 0 265,380
Xylem COM 98419M100   121,817 1,101,718 SH   DFND 3 883,728 0 217,990
Xylem COM 98419M100   29,611 267,802 SH   SOLE 0 97,898 0 169,904
Ziff Davis Inc COM 48123V102   4 53 SH   DFND 3 53 0 0
Zillow Group Inc Class A CL A 98954M101   967 30,990 SH   DFND 1 30,990 0 0
Zillow Group Inc Class A CL A 98954M101   4,869 156,020 SH   DFND 2 47,796 0 108,224
Zillow Group Inc Class A CL A 98954M101   1,732 55,483 SH   DFND 3 55,483 0 0
Zillow Group Inc Class A CL A 98954M101   2,835 90,840 SH   SOLE 0 90,840 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200   31,426 975,649 SH   DFND 1 975,649 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200   22,120 686,756 SH   DFND 2 206,384 0 480,372
Zillow Group Inc Class C CL C CAP STK 98954M200   7,570 235,012 SH   DFND 3 235,012 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200   18,797 583,573 SH   SOLE 0 583,573 0 0
Zoom Video Communications Inc CL A 98980L101   96,865 1,429,957 SH   DFND 1 1,429,957 0 0
Zoom Video Communications Inc CL A 98980L101   291,522 4,303,538 SH   DFND 2 2,669,707 0 1,633,831
Zoom Video Communications Inc CL A 98980L101   38,154 563,248 SH   DFND 3 472,095 0 91,153
Zoom Video Communications Inc CL A 98980L101   143,861 2,123,720 SH   SOLE 0 1,644,034 0 479,686
ZoomInfo Technologies COM 98980F104   13 446 SH   DFND 3 446 0 0
Zuora Inc Class A COM CL A 98983V106   12,785 2,010,224 SH   DFND 1 2,010,224 0 0
Zuora Inc Class A COM CL A 98983V106   10,564 1,661,033 SH   DFND 2 500,135 0 1,160,898
Zuora Inc Class A COM CL A 98983V106   4,233 665,561 SH   DFND 3 665,561 0 0
Zuora Inc Class A COM CL A 98983V106   4,970 781,436 SH   SOLE 0 781,436 0 0
Zynex COM 98986M103   7 481 SH   DFND 3 481 0 0
dLocal CL A G29018101   8,622 553,728 SH   DFND 1 553,728 0 0
dLocal CL A G29018101   2 142 SH   DFND 2 142 0 0
dLocal CL A G29018101   3,177 204,048 SH   DFND 3 0 0 204,048
iRobot COM 462726100   8,497 176,548 SH   DFND 2 54,471 0 122,077
iRobot COM 462726100   1,330 27,636 SH   DFND 1 27,636 0 0
iRobot COM 462726100   3,191 66,292 SH   DFND 3 66,292 0 0
nLIGHT COM 65487K100   5 468 SH   DFND 3 468 0 0