The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Axcella Health Inc COM 05454B105 21,616 12,640,890 SH   DFND 2,3 0 12,640,890 0
Axcella Health Inc COM 05454B105 7,637 4,465,866 SH   DFND 3,4 0 4,465,866 0
Axcella Health Inc COM 05454B105 3,011 1,761,029 SH   DFND 3 0 1,761,029 0
Codiak Biosciences Inc COM 192010106 2,383 3,054,687 SH   DFND 1,3 0 3,054,687 0
Codiak Biosciences Inc COM 192010106 379 485,949 SH   DFND 3 0 485,949 0
Denali Therapeutics Inc COM 24823R105 80,407 2,619,968 SH   DFND 1,3 0 2,619,968 0
Evelo Biosciences Inc COM 299734103 21,329 10,205,282 SH   DFND 1,3 0 10,205,282 0
Evelo Biosciences Inc COM 299734103 21,240 10,162,664 SH   DFND 2,3 0 10,162,664 0
Evelo Biosciences Inc COM 299734103 11,485 5,495,324 SH   DFND 3,4 0 5,495,324 0
Evelo Biosciences Inc COM 299734103 17,179 8,219,791 SH   DFND 3,6 0 8,219,791 0
Evelo Biosciences Inc COM 299734103 34,160 16,344,267 SH   DFND 3 0 16,344,267 0
Foghorn Therapeutics Inc COM 344174107 80,059 9,330,878 SH   DFND 1,3 0 9,330,878 0
Foghorn Therapeutics Inc COM 344174107 12,797 1,491,441 SH   DFND 3,4 0 1,491,441 0
Foghorn Therapeutics Inc COM 344174107 15,888 1,851,801 SH   DFND 3,5 0 1,851,801 0
Moderna Inc COM 60770K107 1,523,393 12,882,819 SH   DFND 2,3 0 12,882,819 0
Moderna Inc COM 60770K107 464 3,924 SH   DFND 3 0 3,924 0
Omega Therapeutics Inc COM 68217N105 37,858 6,984,856 SH   DFND 1,3 0 6,984,856 0
Omega Therapeutics Inc COM 68217N105 29,890 5,514,707 SH   DFND 3,5 0 5,514,707 0
Omega Therapeutics Inc COM 68217N105 5,261 970,588 SH   DFND 3,6 0 970,588 0
Omega Therapeutics Inc COM 68217N105 46,706 8,617,413 SH   DFND 3,7 0 8,617,413 0
Omega Therapeutics Inc COM 68217N105 20,676 3,814,705 SH   DFND 3 0 3,814,705 0
Rubius Therapeutics Inc COM 78116T103 5,009 11,648,828 SH   DFND 1,3 0 11,648,828 0
Rubius Therapeutics Inc COM 78116T103 10,416 24,223,995 SH   DFND 2,3 0 24,223,995 0
Rubius Therapeutics Inc COM 78116T103 1,132 2,633,703 SH   DFND 3,4 0 2,633,703 0
Sana Biotechnology Inc COM 799566104 78,435 13,072,570 SH   DFND 1,3 0 13,072,570 0
Sana Biotechnology Inc COM 799566104 58,351 9,725,122 SH   DFND 3,7 0 9,725,122 0
Sana Biotechnology Inc COM 799566104 68,648 11,441,326 SH   DFND 3 0 11,441,326 0
Seres Therapeutics Inc COM 81750R102 54,267 8,452,876 SH   DFND 2,3 0 8,452,876 0
Seres Therapeutics Inc COM 81750R102 19,022 2,962,963 SH   DFND 3,7 0 2,962,963 0
Seres Therapeutics Inc COM 81750R102 37,722 5,875,711 SH   DFND 3,6 0 5,875,711 0
Seres Therapeutics Inc COM 81750R102 37,400 5,825,495 SH   DFND 3 0 5,825,495 0
Sigilon Therapeutics Inc COM 82657L107 4,444 8,888,888 SH   DFND 1,3 0 8,888,888 0
Sigilon Therapeutics Inc COM 82657L107 741 1,481,481 SH   DFND 3,5 0 1,481,481 0
Syros Pharmaceuticals Inc COM 87184Q206 1,892 293,848 SH   DFND 2,3 0 293,848 0
Syros Pharmaceuticals Inc COM 87184Q206 4,508 700,000 SH   DFND 3 0 700,000 0