The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AADI BIOSCIENCE INC COM 00032Q104 2,826 200,000 SH   SOLE   200,000 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 526 1,000,000 SH   SOLE   1,000,000 0 0
AEROVATE THERAPEUTICS INC COM 008064107 2,487 150,000 SH   SOLE   150,000 0 0
ALTIMMUNE INC COM NEW 02155H200 5,555 435,000 SH   SOLE   435,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 5,220 500,000 SH   SOLE   500,000 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101 15,483 550,000 SH   SOLE   550,000 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101 14,075 500,000 SH Put SOLE   500,000 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 18,783 275,000 SH   SOLE   275,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 9,810 95,000 SH   SOLE   95,000 0 0
ASTRIA THERAPEUTICS INC COM 04635X102 4,520 500,000 SH   SOLE   500,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104 6,693 150,000 SH Call SOLE   150,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104 13,386 300,000 SH   SOLE   300,000 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 6,615 525,000 SH   SOLE   525,000 0 0
BIOGEN INC COM 09062X103 1,001 3,750 SH   SOLE   3,750 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 4,283 65,000 SH   SOLE   65,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201 8,952 600,000 SH   SOLE   600,000 0 0
CTI BIOPHARMA CORP COM 12648L601 11,640 2,000,000 SH   SOLE   2,000,000 0 0
DESIGN THERAPEUTICS INC COM 25056L103 1,672 100,000 SH   SOLE   100,000 0 0
DICE THERAPEUTICS INC COM 23345J104 14,196 700,000 SH Call SOLE   700,000 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 4,642 75,000 SH   SOLE   75,000 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 2,792 60,000 SH   SOLE   60,000 0 0
IVERIC BIO INC COM 46583P102 1,100 61,300 SH Call SOLE   61,300 0 0
IVERIC BIO INC COM 46583P102 8,319 463,700 SH   SOLE   463,700 0 0
KARUNA THERAPEUTICS INC COM 48576A100 6,748 30,000 SH   SOLE   30,000 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 4,520 525,000 SH   SOLE   525,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 1,625 25,000 SH   SOLE   25,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 12,222 175,000 SH   SOLE   175,000 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 2,328 300,000 SH   SOLE   300,000 0 0
RAPT THERAPEUTICS INC COM 75382E109 2,165 90,000 SH   SOLE   90,000 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 18,219 725,000 SH   SOLE   725,000 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 5,026 200,000 SH Call SOLE   200,000 0 0
RELMADA THERAPEUTICS INC COM 75955J402 18,510 500,000 SH Put SOLE   500,000 0 0
RELMADA THERAPEUTICS INC COM 75955J402 15,734 425,000 SH   SOLE   425,000 0 0
REVANCE THERAPEUTICS INC COM 761330109 10,530 390,000 SH   SOLE   390,000 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 1,593 65,000 SH   SOLE   65,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 12,159 110,000 SH   SOLE   110,000 0 0
SEAGEN INC COM 81181C104 6,842 50,000 SH Call SOLE   50,000 0 0
SPDR SER TR S&P BIOTECH 78464A870 39,660 500,000 SH Put SOLE   500,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 4,806 200,000 SH   SOLE   200,000 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103 2,054 120,000 SH   SOLE   120,000 0 0
TRICIDA INC COM 89610F101 2,096 200,000 SH   SOLE   200,000 0 0
TRICIDA INC COM 89610F101 5,240 500,000 SH Call SOLE   500,000 0 0
VAXCYTE INC COM 92243G108 8,640 360,000 SH   SOLE   360,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 10,973 535,000 SH   SOLE   535,000 0 0