SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* Chione Ltd (Last) (First) (Middle) SIMOU MENARDOU 5, KIFISIA COURT, OFFICE 225 (Street) LARNACA G4 6015 (City) (State) (Zip)	2. Date of Event Requiring Statement (Month/Day/Year) 11/09/2022	3. Issuer Name and Ticker or Trading Symbol Acrivon Therapeutics, Inc. [ ACRV ]
		4. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)	5. If Amendment, Date of Original Filed (Month/Day/Year) 11/09/2022
			6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Series A-1 Preferred Stock(1)	(1)	(2)	Common Stock	3,445,940(3)	$5.6225(3)	D(4)(5)(6)(7)
Series B Preferred Stock(1)	(1)	(2)	Common Stock	10,657(3)	$14.0745(3)	D(4)(5)(6)(7)

1. Name and Address of Reporting Person* Chione Ltd (Last) (First) (Middle) SIMOU MENARDOU 5, KIFISIA COURT, OFFICE 225 (Street) LARNACA G4 6015 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Czernik Marcin (Last) (First) (Middle) C/O CHIONE LIMITED, SIMOU MENARDOU 5, KIFISIA COURT, OFFICE 225 (Street) CHESIERES V8 1885 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Hadjimichael Andreas (Last) (First) (Middle) C/O CHIONE LIMITED, SIMOU MENARDOU 5, KIFISIA COURT, OFFICE 225 (Street) LARNACA G4 6015 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Nikolaou Anastasis (Last) (First) (Middle) C/O CHIONE LTD/ SIMOU MENARDOU 5 KIFISIA COURT,OFFICE 225 (Street) LARNACA G4 6015 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Smolokowski Wiaczeslaw (Last) (First) (Middle) CHALET LENOTCHKA CH.DE BARNOUD (Street) CHESIERES V8 1885 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

Explanation of Responses:

1. Each share of Preferred Stock is convertible into Common Stock, without payment of further consideration, at any time at the holder's election and automatically upon the closing of the issuer's initial public offering.

2. The shares of Preferred Stock have no expiration date.

3. The total number of shares of Common Stock issuable upon conversion of each series of Preferred Stock and the respective conversion prices thereof reflect the issuer's 2.466:1 reverse stock split effected in connection with the issuer's initial public offering.

4. Shares of Preferred Stock owned directly by Chione Limited ("Chione").

5. Chione's directors, Marcin Czernik, Andreas Hadjimichael and Anastasis Nikolaou, and its sole shareholder, Wiaczeslaw Smolokowski, may be deemed to share beneficial ownership of the shares of Preferred Stock directly owned by Chione (and of the Common Stock issuable upon conversion of those shares of Preferred Stock).

6. Each reporting person states that neither the filing of this Form 3 nor anything herein shall be deemed an admission that such person is, for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Act"), or otherwise, the beneficial owner of any securities covered by this Form 3. Each reporting person disclaims beneficial ownership of the securities covered by this statement, except to the extent of the pecuniary interest of such person in such securities.

7. Each reporting person may be deemed to be a member of a group with respect to the issuer or securities of the issuer for purposes of Section 13(d) or 13(g) of the Act. Each reporting person declares that neither the filing of this Form 3 nor anything herein shall be construed as an admission that such person is, for the purposes of Section 13(d) or 13(g) of the Act or any other purpose, a member of a group with respect to the issuer or securities of the issuer.

Remarks:

This Form 3/A is being filed in order to add Anastasis Nikolaou (whose director position and beneficial ownership were previously disclosed) as a reporting person. Exhibit Index Exhibit 24.1 - Power of Attorney, dated October 10, 2022, made by Marcin Czernik and Chione Limited in favor of Shalom Leaf (filed with the Form 3, filed on behalf of Chione Limited et al on 11/09/22) Exhibit 24.2 - Power of Attorney, dated October 10, 2022, made by Andreas Hadjimichael and Chione Limited in favor of Shalom Leaf (filed with the Form 3, filed on behalf of Chione Limited et al on 11/09/22) Exhibit 24.3 - Power of Attorney, dated October 10, 2022, made by Wiaczeslaw Smolokowski in favor of Shalom Leaf (filed with the Form 3, filed on behalf of Chione Limited et al on 11/09/22) Exhibit 24.4 - Power of Attorney, dated October 10, 2022, made by Anastasis Nikolaou in favor of Shalom Leaf (filed herewith) Exhibit 99.1 - Joint Filer Information (filed herewith) Exhibit 99.2 - Joint Filing Agreement (filed herewith)

	Chione Limited, by /s/ Shalom Leaf, as attorney-in fact by power of attorney	11/14/2022
	Marcin Czernik, by /s/ Shalom Leaf, as attorney-in fact by power of attorney	11/14/2022
	Andreas Hadjimichael, by /s/ Shalom Leaf, as attorney-in fact by power of attorney	11/14/2022
	Anastasis Nikolaou, by /s/ Shalom Leaf, as attorney-in fact by power of attorney	11/14/2022
	Wiaczeslaw Smolokowski, by /s/ Shalom Leaf, as attorney-in fact by power of attorney	11/14/2022
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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