The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X Genomics Inc Class A CL A COM 88025U109 105,918 2,340,730 SH   DFND 1 2,340,730 0 0
10X Genomics Inc Class A CL A COM 88025U109 106,402 2,351,425 SH   DFND 2 2,057,070 0 294,355
10X Genomics Inc Class A CL A COM 88025U109 61,869 1,367,274 SH   DFND 3 1,118,436 0 248,838
10X Genomics Inc Class A CL A COM 88025U109 104,959 2,319,542 SH   SOLE 0 2,160,498 0 159,044
1Life Healthcare COM 68269G107 3 445 SH   DFND 3 445 0 0
2U COM 90214J101 3 319 SH   DFND 3 319 0 0
2seventy bio COM 901384107 4 286 SH   DFND 3 286 0 0
8x8 Inc COM 282914100 11 2,045 SH   DFND 3 2,045 0 0
908 Devices COM 65443P102 5 249 SH   DFND 3 249 0 0
A. O. Smith COM 831865209 14 263 SH   DFND 3 263 0 0
ACM Research COM 00108J109 11 660 SH   DFND 3 660 0 0
AJ Gallagher & Co COM 363576109 178,385 1,094,120 SH   DFND 1 1,094,120 0 0
AJ Gallagher & Co COM 363576109 492,026 3,017,823 SH   DFND 2 2,754,807 0 263,016
AJ Gallagher & Co COM 363576109 94,976 582,532 SH   DFND 3 354,330 0 228,202
AJ Gallagher & Co COM 363576109 426,644 2,616,805 SH   SOLE 0 1,720,362 0 896,443
Abcellera Biologics Inc COM 00288U106 48,287 4,533,974 SH   DFND 1 4,533,974 0 0
Abcellera Biologics Inc COM 00288U106 32,514 3,052,968 SH   DFND 2 1,349,209 0 1,703,759
Abcellera Biologics Inc COM 00288U106 42,515 3,992,048 SH   DFND 3 3,239,556 0 752,492
Abcellera Biologics Inc COM 00288U106 18,911 1,775,725 SH   SOLE 0 1,244,424 0 531,301
Abiomed COM 003654100 270,588 1,093,241 SH   DFND 1 1,093,241 0 0
Abiomed COM 003654100 375,566 1,517,376 SH   DFND 2 1,376,636 0 140,740
Abiomed COM 003654100 121,820 492,184 SH   DFND 3 377,620 0 114,564
Abiomed COM 003654100 150,244 607,020 SH   SOLE 0 415,005 0 192,015
Acadia Pharmaceuticals Inc COM 004225108 8 544 SH   DFND 3 544 0 0
Accelerate Diagnostics COM 00430H102 0 418 SH   DFND 3 418 0 0
Accenture 'A' COM G1151C101 13 48 SH   DFND 3 48 0 0
Acutus Medical COM 005111109 0 424 SH   DFND 3 424 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 10,296 6,056,564 SH   DFND 1 6,056,564 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 5,890 3,464,606 SH   DFND 2 1,041,546 0 2,423,060
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 2,517 1,480,697 SH   DFND 3 1,480,697 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 7,343 4,319,479 SH   SOLE 0 4,319,479 0 0
Adicet Bio Inc COM 007002108 1,364 93,449 SH   DFND 1 93,449 0 0
Adicet Bio Inc COM 007002108 1,287 88,177 SH   SOLE 0 88,177 0 0
Adobe Systems COM 00724F101 44,853 122,530 SH   DFND 1 122,530 0 0
Adobe Systems COM 00724F101 140,249 383,130 SH   DFND 2 328,481 0 54,649
Adobe Systems COM 00724F101 26,985 73,717 SH   DFND 3 42,764 0 30,953
Adobe Systems COM 00724F101 124,607 340,400 SH   SOLE 0 221,058 0 119,342
Advanced Micro Devices Inc COM 007903107 9 118 SH   DFND 3 118 0 0
Aerovironment COM 008073108 17,518 213,117 SH   DFND 1 213,117 0 0
Aerovironment COM 008073108 18,904 229,973 SH   DFND 2 70,229 0 159,744
Aerovironment COM 008073108 8,503 103,447 SH   DFND 3 103,447 0 0
Aerovironment COM 008073108 18,131 220,567 SH   SOLE 0 220,567 0 0
Affirm Holdings Inc Class A COM CL A 00827B106 61,562 3,408,756 SH   DFND 1 3,408,756 0 0
Affirm Holdings Inc Class A COM CL A 00827B106 153,698 8,510,383 SH   DFND 2 5,582,031 0 2,928,352
Affirm Holdings Inc Class A COM CL A 00827B106 16,627 920,653 SH   DFND 3 758,287 0 162,366
Affirm Holdings Inc Class A COM CL A 00827B106 105,595 5,846,900 SH   SOLE 0 5,015,776 0 831,124
Agios Pharmaceuticals Inc COM 00847X104 4 186 SH   DFND 3 186 0 0
Agnico Eagle Mines COM 008474108 156 3,400 SH   DFND 1 3,400 0 0
Agora Inc ADR ADS 00851L103 3,215 489,288 SH   DFND 1 489,288 0 0
Agora Inc ADR ADS 00851L103 1,675 255,012 SH   SOLE 0 255,012 0 0
Albemarle Corp COM 012653101 154,146 737,613 SH   DFND 1 737,613 0 0
Albemarle Corp COM 012653101 332,113 1,589,211 SH   DFND 2 1,443,453 0 145,758
Albemarle Corp COM 012653101 65,632 314,057 SH   DFND 3 198,429 0 115,628
Albemarle Corp COM 012653101 266,551 1,275,488 SH   SOLE 0 891,654 0 383,834
Alector Inc COM 014442107 635 62,503 SH   DFND 1 62,503 0 0
Alector Inc COM 014442107 1,336 131,492 SH   DFND 2 131,492 0 0
Alector Inc COM 014442107 1,631 160,497 SH   DFND 3 160,497 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 1 13 SH   DFND 4 13 0 0
Allbirds Inc COM CL A 01675A109 2,678 681,466 SH   DFND 2 242,231 0 439,235
Allbirds Inc COM CL A 01675A109 2,698 686,619 SH   SOLE 0 686,619 0 0
Alnylam Pharmaceuticals COM 02043Q107 377,914 2,591,112 SH   DFND 1 2,591,112 0 0
Alnylam Pharmaceuticals COM 02043Q107 562,772 3,858,566 SH   DFND 2 3,169,179 0 689,387
Alnylam Pharmaceuticals COM 02043Q107 191,992 1,316,368 SH   DFND 3 1,036,771 0 279,597
Alnylam Pharmaceuticals COM 02043Q107 321,218 2,202,388 SH   SOLE 0 1,583,654 0 618,734
Alphabet Inc Class A CAP STK CL A 02079K305 5,511 2,529 SH   DFND 1 2,529 0 0
Alphabet Inc Class A CAP STK CL A 02079K305 26,500 12,160 SH   DFND 2 11,443 0 717
Alphabet Inc Class A CAP STK CL A 02079K305 2,628 1,206 SH   DFND 3 871 0 335
Alphabet Inc Class A CAP STK CL A 02079K305 87,796 40,287 SH   SOLE 0 40,287 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 176,518 80,696 SH   DFND 1 80,696 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 592,079 270,671 SH   DFND 2 247,322 0 23,349
Alphabet Inc Class C CAP STK CL C 02079K107 108,832 49,753 SH   DFND 3 29,179 0 20,574
Alphabet Inc Class C CAP STK CL C 02079K107 414,861 189,655 SH   SOLE 0 109,829 0 79,826
Alteryx Inc COM 02156B103 16 336 SH   DFND 3 336 0 0
Amazon.Com COM 023135106 576,716 5,429,963 SH   DFND 1 5,429,963 0 0
Amazon.Com COM 023135106 1,979,937 18,641,723 SH   DFND 2 11,321,001 0 7,320,722
Amazon.Com COM 023135106 277,103 2,609,010 SH   DFND 3 1,975,800 0 633,210
Amazon.Com COM 023135106 1,185,638 11,163,148 SH   SOLE 0 8,112,481 0 3,050,667
Ambarella SHS G037AX101 18,335 280,100 SH   DFND 1 280,100 0 0
Ambarella SHS G037AX101 10,868 166,027 SH   DFND 2 49,947 0 116,080
Ambarella SHS G037AX101 5,054 77,202 SH   DFND 3 77,202 0 0
Ambarella SHS G037AX101 6,389 97,605 SH   SOLE 0 97,605 0 0
Amdocs COM G02602103 32 386 SH   DFND 3 386 0 0
Ameren COM 023608102 1,168 12,931 SH   DFND 1 12,931 0 0
American Superconductor Corp COM 030111207 3,747 723,370 SH   DFND 1 723,370 0 0
American Superconductor Corp COM 030111207 3,978 768,000 SH   SOLE 0 768,000 0 0
American Tower Corp REIT COM 03027X100 911 3,564 SH   DFND 1 3,564 0 0
American Well Corp Class A COM 03044L105 418 96,754 SH   DFND 1 96,754 0 0
American Well Corp Class A COM 03044L105 853 197,523 SH   DFND 2 197,523 0 0
American Well Corp Class A COM 03044L105 1,457 337,239 SH   DFND 3 337,239 0 0
Amicus Therapeutics Inc COM 03152W109 6 538 SH   DFND 3 538 0 0
Amkor Technology COM 031652100 33 1,976 SH   DFND 3 1,976 0 0
Analog Devices COM 032654105 95,879 656,302 SH   DFND 1 656,302 0 0
Analog Devices COM 032654105 176,836 1,210,462 SH   DFND 2 1,104,662 0 105,800
Analog Devices COM 032654105 37,880 259,292 SH   DFND 3 169,330 0 89,962
Analog Devices COM 032654105 165,845 1,135,222 SH   SOLE 0 797,213 0 338,009
Anterix COM 03676C100 7 162 SH   DFND 3 162 0 0
Apellis Pharmaceuticals COM 03753U106 13 283 SH   DFND 3 283 0 0
AppFolio COM 03783C100 19 212 SH   DFND 3 212 0 0
Appian Corp CL A 03782L101 99,282 2,096,333 SH   DFND 1 2,096,333 0 0
Appian Corp CL A 03782L101 128,882 2,721,316 SH   DFND 2 2,392,355 0 328,961
Appian Corp CL A 03782L101 12,426 262,379 SH   DFND 3 262,379 0 0
Appian Corp CL A 03782L101 30,775 649,816 SH   SOLE 0 649,816 0 0
Apple COM 037833100 47,732 349,123 SH   DFND 1 349,123 0 0
Apple COM 037833100 450 3,289 SH   DFND 2 0 0 3,289
Apple COM 037833100 7,081 51,790 SH   DFND 3 51,790 0 0
Apple COM 037833100 25,923 189,606 SH   SOLE 0 189,606 0 0
Archer-Daniels-Midland Co COM 039483102 12,013 154,806 SH   DFND 2 154,806 0 0
Archer-Daniels-Midland Co COM 039483102 3,261 42,029 SH   SOLE 0 42,029 0 0
Ares Capital Corp COM 04010L103 42,892 2,392,200 SH   DFND 1 2,392,200 0 0
Ares Capital Corp COM 04010L103 105 5,875 SH   DFND 2 5,875 0 0
Ares Capital Corp COM 04010L103 3,748 209,040 SH   DFND 3 209,040 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101 1,415 15,222 SH   DFND 1 15,222 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101 2,954 31,777 SH   DFND 2 31,777 0 0
Ascendis Pharma ADR 1:1 SPON ADR 04351P101 3,607 38,801 SH   DFND 3 38,801 0 0
Asensus Surgical Inc COM 04367G103 2 5,338 SH   DFND 3 5,338 0 0
AstraZeneca ADR COM 046353108 26 400 SH   DFND 3 400 0 0
Atlassian Corp Plc CL A G06242104 94,736 505,526 SH   DFND 1 505,526 0 0
Atlassian Corp Plc CL A G06242104 626,722 3,344,303 SH   DFND 2 1,272,038 0 2,072,265
Atlassian Corp Plc CL A G06242104 97,599 520,808 SH   DFND 3 415,652 0 105,156
Atlassian Corp Plc CL A G06242104 198,541 1,059,452 SH   SOLE 0 459,310 0 600,142
Aurora Innovation Class A Common COM CL A 051774107 28,650 15,000,000 SH   SOLE 0 15,000,000 0 0
AutoZone COM 053332102 4,739 2,205 SH   SOLE 0 2,205 0 0
Avalara Inc COM 05338G106 12 165 SH   DFND 2 165 0 0
Avalara Inc COM 05338G106 324 4,588 SH   DFND 3 4,588 0 0
Avangrid COM 05351W103 974 21,126 SH   DFND 1 21,126 0 0
Avery Dennison Corporation COM 053611109 16 100 SH   DFND 3 100 0 0
Axogen Inc COM 05463X106 4 444 SH   DFND 3 444 0 0
Axon Enterprise Inc COM 05464C101 50,711 544,284 SH   DFND 1 544,284 0 0
Axon Enterprise Inc COM 05464C101 98,954 1,062,076 SH   DFND 2 837,296 0 224,780
Axon Enterprise Inc COM 05464C101 24,333 261,169 SH   DFND 3 191,951 0 69,218
Axon Enterprise Inc COM 05464C101 83,024 891,105 SH   SOLE 0 625,686 0 265,419
Axonics Modulation Technologies COM 05465P101 11 198 SH   DFND 3 198 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 458,627 3,083,618 SH   DFND 2 2,888,408 0 195,210
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 19,401 5,951,140 SH   DFND 1 5,951,140 0 0
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 154,998 47,545,516 SH   DFND 2 26,404,185 0 21,141,331
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 5,365 1,645,743 SH   DFND 3 1,645,743 0 0
Bandwidth COM 05988J103 7 398 SH   DFND 2 398 0 0
Bandwidth COM 05988J103 216 11,463 SH   DFND 3 11,463 0 0
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 6,481 592,408 SH   DFND 1 592,408 0 0
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 4,564 417,226 SH   DFND 2 127,031 0 290,195
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 1,822 166,530 SH   DFND 3 166,530 0 0
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 3,217 294,100 SH   SOLE 0 294,100 0 0
Beam Therapeutics COM 07373V105 15 398 SH   DFND 3 398 0 0
Beam Therapeutics COM 07373V105 398 10,275 SH   SOLE 0 10,275 0 0
BeiGene Ltd SPONSORED ADR 07725L102 48,993 302,706 SH   DFND 1 302,706 0 0
BeiGene Ltd SPONSORED ADR 07725L102 321,216 1,984,650 SH   DFND 2 731,864 0 1,252,786
BeiGene Ltd SPONSORED ADR 07725L102 50,717 313,360 SH   DFND 3 250,642 0 62,718
BeiGene Ltd SPONSORED ADR 07725L102 102,648 634,215 SH   SOLE 0 276,057 0 358,158
Benefitfocus Inc COM 08180D106 2,384 306,448 SH   DFND 1 306,448 0 0
Benefitfocus Inc COM 08180D106 2,258 290,178 SH   DFND 2 82,497 0 207,681
Benefitfocus Inc COM 08180D106 1,352 173,791 SH   DFND 3 173,791 0 0
Benefitfocus Inc COM 08180D106 1,761 226,368 SH   SOLE 0 226,368 0 0
Berkeley Lights Inc COM 084310101 6,539 1,315,767 SH   DFND 1 1,315,767 0 0
Berkeley Lights Inc COM 084310101 3,632 730,704 SH   DFND 2 509,041 0 221,663
Berkeley Lights Inc COM 084310101 5,869 1,180,823 SH   DFND 3 1,004,814 0 176,009
Berkeley Lights Inc COM 084310101 2,245 451,690 SH   SOLE 0 326,690 0 125,000
Beyond Meat Inc COM 08862E109 30,383 1,269,122 SH   DFND 1 1,269,122 0 0
Beyond Meat Inc COM 08862E109 106,216 4,436,740 SH   DFND 2 1,737,014 0 2,699,726
Beyond Meat Inc COM 08862E109 30,637 1,279,751 SH   DFND 3 1,011,410 0 268,341
Beyond Meat Inc COM 08862E109 34,543 1,442,896 SH   SOLE 0 616,081 0 826,815
Bilibili Inc ADR SPONSORED ADR 090040106 1,433 55,974 SH   DFND 3 42,949 0 13,025
BioCryst Pharmaceuticals COM 09058V103 18 1,687 SH   DFND 3 1,687 0 0
BioNTech ADR SPONS ADS 09075V102 92,349 619,379 SH   DFND 1 619,379 0 0
BioNTech ADR SPONS ADS 09075V102 703,760 4,720,057 SH   DFND 2 2,028,480 0 2,691,577
BioNTech ADR SPONS ADS 09075V102 91,346 612,647 SH   DFND 3 511,820 0 100,827
BioNTech ADR SPONS ADS 09075V102 1 4 SH   DFND 4 4 0 0
BioNTech ADR SPONS ADS 09075V102 195,454 1,310,893 SH   SOLE 0 570,078 0 740,815
Biomarin Pharmaceutical Inc COM 09061G101 7 82 SH   DFND 3 82 0 0
Blackline COM 09239B109 30,113 452,142 SH   DFND 1 452,142 0 0
Blackline COM 09239B109 24,704 370,934 SH   DFND 2 110,752 0 260,182
Blackline COM 09239B109 10,659 160,044 SH   DFND 3 160,044 0 0
Blackline COM 09239B109 18,686 280,576 SH   SOLE 0 280,576 0 0
Blackrock Inc COM 09247X101 12 19 SH   DFND 3 19 0 0
Blink Charging COM 09354A100 5 327 SH   DFND 3 327 0 0
Blue Apron Holdings Inc CL A 09523Q200 541 148,506 SH   DFND 1 148,506 0 0
Bluebird Bio Inc COM 09609G100 4 860 SH   DFND 3 860 0 0
Blueprint Medicines Corp COM 09627Y109 16 315 SH   DFND 3 315 0 0
Booking Holdings Inc COM 09857L108 69,215 39,574 SH   DFND 1 39,574 0 0
Booking Holdings Inc COM 09857L108 215,682 123,318 SH   DFND 2 111,731 0 11,587
Booking Holdings Inc COM 09857L108 42,756 24,446 SH   DFND 3 14,247 0 10,199
Booking Holdings Inc COM 09857L108 197,428 112,881 SH   SOLE 0 73,651 0 39,230
Boston Omaha COM 101044105 11 529 SH   DFND 3 529 0 0
Box Inc COM 10316T104 25 979 SH   DFND 3 979 0 0
Brady Corp COM 104674106 9 200 SH   DFND 3 200 0 0
BridgeBio Pharma Inc COM 10806X102 780 85,887 SH   DFND 1 85,887 0 0
BridgeBio Pharma Inc COM 10806X102 1,682 185,242 SH   DFND 2 185,242 0 0
BridgeBio Pharma Inc COM 10806X102 1,937 213,348 SH   DFND 3 213,348 0 0
Bristol Myers Squibb COM 110122108 38 488 SH   DFND 3 488 0 0
Broadridge Finl.Sltn. COM 11133T103 67,544 473,824 SH   DFND 1 473,824 0 0
Broadridge Finl.Sltn. COM 11133T103 226,173 1,586,622 SH   DFND 2 1,449,638 0 136,984
Broadridge Finl.Sltn. COM 11133T103 42,026 294,818 SH   DFND 3 173,169 0 121,649
Broadridge Finl.Sltn. COM 11133T103 187,196 1,313,193 SH   SOLE 0 850,970 0 462,223
Brookfield Renewable COM 11284V105 65,452 1,838,010 SH   DFND 1 1,838,010 0 0
Brookfield Renewable COM 11284V105 105 2,953 SH   DFND 2 2,953 0 0
Brookfield Renewable COM 11284V105 4,169 117,065 SH   DFND 3 117,065 0 0
Brunswick Corp COM 117043109 13 200 SH   DFND 3 200 0 0
Bumble Inc COM CL A 12047B105 11,260 400,000 SH   SOLE 0 400,000 0 0
Burford Capital ORD SHS G17977110 5,761 589,318 SH   DFND 2 501,535 0 87,783
Burford Capital ORD SHS G17977110 10,609 1,085,189 SH   DFND 1 1,085,189 0 0
Burning Rock Biotech Ltd ADR SPON ADS 12233L107 466 160,181 SH   DFND 1 160,181 0 0
Burning Rock Biotech Ltd ADR SPON ADS 12233L107 517 177,712 SH   DFND 3 0 0 177,712
Butterfly Network Inc COM CL A 124155102 735 239,457 SH   DFND 1 239,457 0 0
Butterfly Network Inc COM CL A 124155102 1,153 375,532 SH   DFND 2 375,532 0 0
Butterfly Network Inc COM CL A 124155102 1,884 613,830 SH   DFND 3 613,830 0 0
Butterfly Network Inc COM CL A 124155102 2,493 812,150 SH   SOLE 0 812,150 0 0
C3.ai CL A 12468P104 2 117 SH   DFND 3 117 0 0
CEVA Inc COM 157210105 5,997 178,680 SH   DFND 1 178,680 0 0
CEVA Inc COM 157210105 4,987 148,594 SH   DFND 2 43,073 0 105,521
CEVA Inc COM 157210105 2,339 69,698 SH   DFND 3 69,698 0 0
CEVA Inc COM 157210105 2,769 82,500 SH   SOLE 0 82,500 0 0
CH Robinson Worldwide COM NEW 12541W209 36,251 357,611 SH   DFND 1 357,611 0 0
CH Robinson Worldwide COM NEW 12541W209 345 3,408 SH   DFND 2 0 0 3,408
CH Robinson Worldwide COM NEW 12541W209 5,318 52,464 SH   DFND 3 52,464 0 0
CH Robinson Worldwide COM NEW 12541W209 20,009 197,381 SH   SOLE 0 197,381 0 0
CRH Plc ADR ADR 12626K203 2 60 SH   DFND 4 60 0 0
CS Disco Inc COM 126327105 13 700 SH   DFND 2 700 0 0
CS Disco Inc COM 126327105 352 19,527 SH   DFND 3 19,527 0 0
Calavo Growers Inc COM 128246105 5 113 SH   DFND 3 113 0 0
Calix Inc COM 13100M509 12 353 SH   DFND 2 353 0 0
Calix Inc COM 13100M509 334 9,794 SH   DFND 3 9,794 0 0
Cardlytics Inc COM 14161W105 8,788 393,924 SH   DFND 1 393,924 0 0
Cardlytics Inc COM 14161W105 7,468 334,732 SH   DFND 2 100,504 0 234,228
Cardlytics Inc COM 14161W105 3,296 147,731 SH   DFND 3 147,731 0 0
Cardlytics Inc COM 14161W105 5,902 264,524 SH   SOLE 0 264,524 0 0
Cargurus Inc COM 141788109 23 1,066 SH   DFND 2 1,066 0 0
Cargurus Inc COM 141788109 641 29,842 SH   DFND 3 29,842 0 0
Carmax Inc COM 143130102 4,035 44,597 SH   SOLE 0 44,597 0 0
Carvana COM 146869102 36,267 1,606,170 SH   DFND 1 1,606,170 0 0
Carvana COM 146869102 126,697 5,611,044 SH   DFND 2 3,273,647 0 2,337,397
Carvana COM 146869102 16,646 737,182 SH   DFND 3 572,010 0 165,172
Carvana COM 146869102 66,549 2,947,233 SH   SOLE 0 2,087,886 0 859,347
Castle Biosciences COM 14843C105 5 225 SH   DFND 3 225 0 0
Cbre Group Inc CL A 12504L109 58,973 801,152 SH   DFND 1 801,152 0 0
Cbre Group Inc CL A 12504L109 206,880 2,810,484 SH   DFND 2 2,578,745 0 231,739
Cbre Group Inc CL A 12504L109 35,595 483,561 SH   DFND 3 281,696 0 201,865
Cbre Group Inc CL A 12504L109 163,516 2,221,382 SH   SOLE 0 1,463,050 0 758,332
Cellectis ADR SPONS ADS 15117K103 1,366 482,819 SH   DFND 1 482,819 0 0
Cellectis ADR SPONS ADS 15117K103 616 217,613 SH   DFND 2 174,990 0 42,623
Cellectis ADR SPONS ADS 15117K103 511 180,500 SH   SOLE 0 180,500 0 0
Celsius Holdings COM 15118V207 15 230 SH   DFND 3 230 0 0
Cemex ADR SPON ADR NEW 151290889 51,230 13,068,778 SH   DFND 1 13,068,778 0 0
Cemex ADR SPON ADR NEW 151290889 173,983 44,383,405 SH   DFND 2 11,510,562 0 32,872,843
Cemex ADR SPON ADR NEW 151290889 62,060 15,831,670 SH   DFND 3 1,561,634 0 14,270,036
Cemex ADR SPON ADR NEW 151290889 2,520 642,732 SH   DFND 4 642,732 0 0
Cemex ADR SPON ADR NEW 151290889 4,053 1,033,870 SH   SOLE 0 1,033,870 0 0
Certara COM 15687V109 31,971 1,489,790 SH   DFND 1 1,489,790 0 0
Certara COM 15687V109 97,457 4,541,325 SH   DFND 2 4,118,003 0 423,322
Certara COM 15687V109 19,427 905,286 SH   DFND 3 532,338 0 372,948
Certara COM 15687V109 91,301 4,254,488 SH   SOLE 0 2,805,274 0 1,449,214
Cerus COM 157085101 8 1,459 SH   DFND 3 1,459 0 0
ChargePoint Holdings Inc COM CL A 15961R105 96 6,985 SH   DFND 1 6,985 0 0
ChargePoint Holdings Inc COM CL A 15961R105 62,631 4,574,933 SH   SOLE 0 4,574,933 0 0
Charles River Laboratories International COM 159864107 3,380 15,796 SH   SOLE 0 15,796 0 0
Charles Schwab COM 808513105 73,602 1,164,956 SH   DFND 1 1,164,956 0 0
Charles Schwab COM 808513105 237,549 3,759,871 SH   DFND 2 3,423,265 0 336,606
Charles Schwab COM 808513105 44,768 708,585 SH   DFND 3 413,850 0 294,735
Charles Schwab COM 808513105 204,844 3,242,226 SH   SOLE 0 2,123,640 0 1,118,586
Chegg COM 163092109 106,732 5,683,270 SH   DFND 1 5,683,270 0 0
Chegg COM 163092109 150,432 8,010,231 SH   DFND 2 7,021,866 0 988,365
Chegg COM 163092109 22,551 1,200,813 SH   DFND 3 969,617 0 231,196
Chegg COM 163092109 64,537 3,436,474 SH   SOLE 0 2,793,389 0 643,085
Chewy Inc CL A 16679L109 136,463 3,930,372 SH   DFND 1 3,930,372 0 0
Chewy Inc CL A 16679L109 272,136 7,838,014 SH   DFND 2 7,450,996 0 387,018
Chewy Inc CL A 16679L109 31,087 895,349 SH   DFND 3 592,281 0 303,068
Chewy Inc CL A 16679L109 134,349 3,869,495 SH   SOLE 0 2,725,560 0 1,143,935
Chinook Therapeutics COM 16961L106 1,614 92,275 SH   DFND 1 92,275 0 0
Chinook Therapeutics COM 16961L106 3,689 210,918 SH   DFND 2 64,855 0 146,063
Chinook Therapeutics COM 16961L106 1,479 84,574 SH   DFND 3 84,574 0 0
Chinook Therapeutics COM 16961L106 2,047 117,058 SH   SOLE 0 117,058 0 0
Church & Dwight Co Inc COM 171340102 17 179 SH   DFND 3 179 0 0
Cisco Systems COM 17275R102 23,666 555,019 SH   DFND 1 555,019 0 0
Cisco Systems COM 17275R102 222 5,198 SH   DFND 2 0 0 5,198
Cisco Systems COM 17275R102 3,497 82,008 SH   DFND 3 82,008 0 0
Cisco Systems COM 17275R102 12,809 300,399 SH   SOLE 0 300,399 0 0
Clear Secure Inc COM 18467V109 20,000 1,000,000 SH   SOLE 0 1,000,000 0 0
Cloudflare Inc CL A COM 18915M107 181,002 4,137,196 SH   DFND 1 4,137,196 0 0
Cloudflare Inc CL A COM 18915M107 588,770 13,457,602 SH   DFND 2 8,192,182 0 5,265,420
Cloudflare Inc CL A COM 18915M107 76,579 1,750,376 SH   DFND 3 1,371,855 0 378,521
Cloudflare Inc CL A COM 18915M107 208,663 4,769,434 SH   SOLE 0 2,734,739 0 2,034,695
Clover Health Investments Corp COM CL A 18914F103 5,661 2,645,503 SH   SOLE 0 2,645,503 0 0
CoStar Group COM 22160N109 204,822 3,390,539 SH   DFND 1 3,390,539 0 0
CoStar Group COM 22160N109 383,877 6,354,529 SH   DFND 2 6,103,710 0 250,819
CoStar Group COM 22160N109 38,028 629,501 SH   DFND 3 436,617 0 192,884
CoStar Group COM 22160N109 168,139 2,783,303 SH   SOLE 0 2,040,088 0 743,215
Coca Cola COM 191216100 25,803 410,154 SH   DFND 1 410,154 0 0
Coca Cola COM 191216100 481 7,652 SH   DFND 2 0 0 7,652
Coca Cola COM 191216100 1,003 15,944 SH   DFND 3 15,944 0 0
Coca Cola COM 191216100 27,745 441,022 SH   SOLE 0 441,022 0 0
Codexis COM 192005106 28,104 2,686,842 SH   DFND 1 2,686,842 0 0
Codexis COM 192005106 21,456 2,051,206 SH   DFND 2 640,603 0 1,410,603
Codexis COM 192005106 10,694 1,022,397 SH   DFND 3 944,592 0 77,805
Codexis COM 192005106 17,150 1,639,622 SH   SOLE 0 1,639,622 0 0
Cognizant Technology Solutions Corp CL A 192446102 4,529 67,105 SH   DFND 3 67,105 0 0
Cognyte Software ORD SHS M25133105 2 369 SH   DFND 3 369 0 0
Cohen & Steers Inc COM 19247A100 19 301 SH   DFND 3 301 0 0
Coherus BioSciences COM 19249H103 10 1,431 SH   DFND 3 1,431 0 0
Cohu COM 192576106 19 700 SH   DFND 3 700 0 0
Coinbase Global Inc COM CL A 19260Q107 350 7,447 SH   SOLE 0 7,447 0 0
Columbia Sportswear Co COM 198516106 7 95 SH   DFND 3 95 0 0
Commscope Holding Co Inc COM 20337X109 9 1,442 SH   DFND 3 1,442 0 0
Consensus Cloud Solutions COM 20848V105 1 24 SH   DFND 3 24 0 0
Consolidated Edison COM 209115104 85,781 902,006 SH   DFND 1 902,006 0 0
Consolidated Edison COM 209115104 128 1,341 SH   DFND 2 1,341 0 0
Consolidated Edison COM 209115104 5,044 53,036 SH   DFND 3 53,036 0 0
Cooper Cos Inc/The COM 216648402 9,824 31,373 SH   DFND 2 31,373 0 0
Copa Holdings S A CL A P31076105 26,143 412,541 SH   DFND 1 412,541 0 0
Copa Holdings S A CL A P31076105 227,629 3,592,065 SH   DFND 2 2,331,676 0 1,260,389
Copa Holdings S A CL A P31076105 47,126 743,659 SH   DFND 3 83,461 0 660,198
Copa Holdings S A CL A P31076105 2,145 33,847 SH   DFND 4 33,847 0 0
Corning COM 219350105 21 679 SH   DFND 3 679 0 0
Costco Wholesale Corporation COM 22160K105 30 63 SH   DFND 3 63 0 0
Coupang CL A 22266T109 112,984 8,861,490 SH   DFND 1 8,861,490 0 0
Coupang CL A 22266T109 997,249 78,215,607 SH   DFND 2 51,139,522 0 27,076,085
Coupang CL A 22266T109 87,496 6,862,398 SH   DFND 3 4,365,955 0 2,496,443
Coupang CL A 22266T109 279 21,849 SH   DFND 4 21,849 0 0
Coupang CL A 22266T109 183,512 14,393,090 SH   SOLE 0 7,503,307 0 6,889,783
Coursera Inc COM 22266M104 90,714 6,397,309 SH   DFND 1 6,397,309 0 0
Coursera Inc COM 22266M104 100,602 7,094,614 SH   DFND 2 6,439,936 0 654,678
Coursera Inc COM 22266M104 37,884 2,671,657 SH   DFND 3 2,150,083 0 521,574
Coursera Inc COM 22266M104 24,749 1,745,339 SH   SOLE 0 1,378,176 0 367,163
Credicorp COM G2519Y108 19,395 161,745 SH   DFND 1 161,745 0 0
Credicorp COM G2519Y108 100,659 839,454 SH   DFND 2 329,333 0 510,121
Credicorp COM G2519Y108 33,714 281,159 SH   DFND 3 35,440 0 245,719
Credicorp COM G2519Y108 1,682 14,031 SH   DFND 4 14,031 0 0
CrowdStrike Holdings COM 22788C105 19 114 SH   DFND 3 114 0 0
Cullen/Frost Bankers COM 229899109 23,556 202,284 SH   DFND 1 202,284 0 0
Cullen/Frost Bankers COM 229899109 218 1,874 SH   DFND 2 0 0 1,874
Cullen/Frost Bankers COM 229899109 3,479 29,878 SH   DFND 3 29,878 0 0
Cullen/Frost Bankers COM 229899109 12,649 108,625 SH   SOLE 0 108,625 0 0
Curevac N.V. COM N2451R105 3,909 287,249 SH   DFND 2 287,249 0 0
CyberArk Software Ltd SHS M2682V108 11,570 90,416 SH   DFND 1 90,416 0 0
CyberArk Software Ltd SHS M2682V108 20,211 157,949 SH   DFND 2 47,542 0 110,407
CyberArk Software Ltd SHS M2682V108 9,195 71,857 SH   DFND 3 71,857 0 0
CyberArk Software Ltd SHS M2682V108 14,730 115,118 SH   SOLE 0 115,118 0 0
Cytokinetics Inc COM NEW 23282W605 13 340 SH   DFND 3 340 0 0
Dada Nexus Ltd ADR ADS 23344D108 21,589 2,661,997 SH   DFND 1 2,661,997 0 0
Dada Nexus Ltd ADR ADS 23344D108 9,483 1,169,302 SH   DFND 2 1,169,302 0 0
Dada Nexus Ltd ADR ADS 23344D108 329 40,516 SH   DFND 3 40,516 0 0
Dada Nexus Ltd ADR ADS 23344D108 6,348 782,705 SH   SOLE 0 782,705 0 0
Darden Restaurants COM 237194105 9 82 SH   DFND 3 82 0 0
Datadog COM 23804L103 141,924 1,490,172 SH   DFND 1 1,490,172 0 0
Datadog COM 23804L103 276,771 2,906,035 SH   DFND 2 2,773,385 0 132,650
Datadog COM 23804L103 30,365 318,829 SH   DFND 3 213,287 0 105,542
Datadog COM 23804L103 128,937 1,353,814 SH   SOLE 0 954,476 0 399,338
Deere & Co COM 244199105 138,491 462,453 SH   DFND 1 462,453 0 0
Deere & Co COM 244199105 83,516 278,880 SH   DFND 2 166,857 0 112,023
Deere & Co COM 244199105 141,645 472,985 SH   DFND 3 371,345 0 101,640
Deere & Co COM 244199105 36,200 120,880 SH   SOLE 0 51,286 0 69,594
Denali Therapeutics COM 24823R105 85,271 2,897,408 SH   DFND 1 2,897,408 0 0
Denali Therapeutics COM 24823R105 124,356 4,225,497 SH   DFND 2 4,107,106 0 118,391
Denali Therapeutics COM 24823R105 13,089 444,740 SH   DFND 3 406,120 0 38,620
Denali Therapeutics COM 24823R105 214,890 7,301,729 SH   SOLE 0 7,301,729 0 0
DermTech COM 24984K105 2 286 SH   DFND 3 286 0 0
Dexcom Inc COM 252131107 218,335 2,929,495 SH   DFND 1 2,929,495 0 0
Dexcom Inc COM 252131107 677,572 9,091,261 SH   DFND 2 3,633,297 0 5,457,964
Dexcom Inc COM 252131107 227,556 3,053,212 SH   DFND 3 2,424,201 0 629,011
Dexcom Inc COM 252131107 225,485 3,025,431 SH   SOLE 0 1,310,658 0 1,714,773
Digimarc COM 25381B101 3,711 262,445 SH   DFND 1 262,445 0 0
Digimarc COM 25381B101 3,967 280,535 SH   DFND 2 85,662 0 194,873
Digimarc COM 25381B101 1,839 130,075 SH   DFND 3 130,075 0 0
Digimarc COM 25381B101 2,188 154,711 SH   SOLE 0 154,711 0 0
Digital Realty Trust REIT COM 253868103 475 3,656 SH   DFND 1 3,656 0 0
Docebo COM 25609L105 4,615 161,041 SH   DFND 2 137,496 0 23,545
Docebo COM 25609L105 8 267 SH   DFND 3 267 0 0
Dolby Laboratories 'A' COM 25659T107 18,703 261,366 SH   DFND 1 261,366 0 0
Dolby Laboratories 'A' COM 25659T107 177 2,480 SH   DFND 2 0 0 2,480
Dolby Laboratories 'A' COM 25659T107 2,764 38,623 SH   DFND 3 38,623 0 0
Dolby Laboratories 'A' COM 25659T107 14,360 200,666 SH   SOLE 0 200,666 0 0
Dollar General Corp COM 256677105 17 69 SH   DFND 3 69 0 0
Domo COM 257554105 9 321 SH   DFND 3 321 0 0
Donaldson COM 257651109 21 436 SH   DFND 3 436 0 0
Doordash Inc COM 25809K105 95,102 1,482,034 SH   DFND 1 1,482,034 0 0
Doordash Inc COM 25809K105 195,991 3,054,245 SH   DFND 2 2,891,698 0 162,547
Doordash Inc COM 25809K105 24,202 377,150 SH   DFND 3 246,462 0 130,688
Doordash Inc COM 25809K105 167,850 2,615,713 SH   SOLE 0 2,122,664 0 493,049
Dropbox CL A 26210C104 18 881 SH   DFND 3 881 0 0
Duck Creek Technologies SHS 264120106 5 355 SH   DFND 3 355 0 0
Duke Realty Corporation REIT COM 264411505 96,718 1,760,103 SH   DFND 1 1,760,103 0 0
Duke Realty Corporation REIT COM 264411505 206 3,740 SH   DFND 2 3,740 0 0
Duke Realty Corporation REIT COM 264411505 8,795 160,051 SH   DFND 3 160,051 0 0
Duolingo Inc CL A COM 26603R106 86,326 986,019 SH   DFND 1 986,019 0 0
Duolingo Inc CL A COM 26603R106 93,078 1,063,143 SH   DFND 2 971,368 0 91,775
Duolingo Inc CL A COM 26603R106 32,768 374,273 SH   DFND 3 301,233 0 73,040
Duolingo Inc CL A COM 26603R106 20,136 229,989 SH   SOLE 0 179,822 0 50,167
EHang Holdings Ltd ADR ADS 26853E102 29 3,105 SH   DFND 1 3,105 0 0
Eargo COM 270087109 0 263 SH   DFND 3 263 0 0
Ecolab COM 278865100 61,205 398,054 SH   DFND 1 398,054 0 0
Ecolab COM 278865100 39,306 255,630 SH   DFND 2 159,110 0 96,520
Ecolab COM 278865100 62,876 408,920 SH   DFND 3 321,066 0 87,854
Ecolab COM 278865100 14,025 91,211 SH   SOLE 0 32,065 0 59,146
Edwards Lifesciences Corp COM 28176E108 3,982 41,875 SH   DFND 1 41,875 0 0
Edwards Lifesciences Corp COM 28176E108 21,970 231,040 SH   DFND 2 231,040 0 0
Edwards Lifesciences Corp COM 28176E108 10,157 106,815 SH   DFND 3 106,815 0 0
Edwards Lifesciences Corp COM 28176E108 3,851 40,495 SH   SOLE 0 40,495 0 0
Electronic Arts, Inc. COM 285512109 21 170 SH   DFND 3 170 0 0
Electronic Arts, Inc. COM 285512109 4,291 35,276 SH   SOLE 0 35,276 0 0
Elevance Health Inc COM 036752103 256,532 531,585 SH   DFND 1 531,585 0 0
Elevance Health Inc COM 036752103 828,717 1,717,263 SH   DFND 2 1,564,837 0 152,426
Elevance Health Inc COM 036752103 156,790 324,900 SH   DFND 3 191,160 0 133,740
Elevance Health Inc COM 036752103 720,078 1,492,142 SH   SOLE 0 975,217 0 516,925
Emergent Biosolutions Inc COM 29089Q105 12 385 SH   DFND 3 385 0 0
Enanta Pharmaceuticals COM 29251M106 15 318 SH   DFND 3 318 0 0
Enphase Energy Inc COM 29355A107 201 1,029 SH   DFND 1 1,029 0 0
Enphase Energy Inc COM 29355A107 18 92 SH   DFND 3 92 0 0
Estee Lauder 'A' COM 518439104 87,879 345,069 SH   DFND 1 345,069 0 0
Estee Lauder 'A' COM 518439104 307,363 1,206,908 SH   DFND 2 1,106,723 0 100,185
Estee Lauder 'A' COM 518439104 54,115 212,491 SH   DFND 3 124,432 0 88,059
Estee Lauder 'A' COM 518439104 253,891 996,941 SH   SOLE 0 654,897 0 342,044
EverQuote Inc COM CL A 30041R108 6,356 718,967 SH   DFND 1 718,967 0 0
EverQuote Inc COM CL A 30041R108 2,327 263,204 SH   DFND 2 78,082 0 185,122
EverQuote Inc COM CL A 30041R108 1,446 163,605 SH   DFND 3 163,605 0 0
EverQuote Inc COM CL A 30041R108 2,047 231,550 SH   SOLE 0 231,550 0 0
Everbridge Inc COM 29978A104 9,226 330,786 SH   DFND 1 330,786 0 0
Everbridge Inc COM 29978A104 5,638 202,169 SH   DFND 2 61,293 0 140,876
Everbridge Inc COM 29978A104 2,631 94,337 SH   DFND 3 94,337 0 0
Everbridge Inc COM 29978A104 4,140 148,446 SH   SOLE 0 148,446 0 0
Eversource Energy COM 30040W108 70,790 838,049 SH   DFND 1 838,049 0 0
Eversource Energy COM 30040W108 109 1,293 SH   DFND 2 1,293 0 0
Eversource Energy COM 30040W108 4,325 51,207 SH   DFND 3 51,207 0 0
Exact Sciences COM 30063P105 44,048 1,118,241 SH   DFND 1 1,118,241 0 0
Exact Sciences COM 30063P105 62,744 1,592,886 SH   DFND 2 1,148,315 0 444,571
Exact Sciences COM 30063P105 20,059 509,233 SH   DFND 3 404,495 0 104,738
Exact Sciences COM 30063P105 47,037 1,194,147 SH   SOLE 0 872,970 0 321,177
Exelixis COM 30161Q104 26 1,230 SH   DFND 3 1,230 0 0
Exelon Corporation COM 30161N101 1,289 28,452 SH   DFND 1 28,452 0 0
Expedia Group Inc COM 30212P303 17 176 SH   DFND 3 176 0 0
Expeditors Intl COM 302130109 10 107 SH   DFND 3 107 0 0
Expensify Inc COM CL A 30219Q106 12,402 697,160 SH   DFND 1 697,160 0 0
Expensify Inc COM CL A 30219Q106 18 1,020 SH   DFND 2 1,020 0 0
Expensify Inc COM CL A 30219Q106 502 28,200 SH   DFND 3 28,200 0 0
Expensify Inc COM CL A 30219Q106 6,389 359,144 SH   SOLE 0 359,144 0 0
Exponent COM 30214U102 22 242 SH   DFND 3 242 0 0
Exscientia Ltd ADR ADS 30223G102 11,648 1,069,649 SH   DFND 1 1,069,649 0 0
Exscientia Ltd ADR ADS 30223G102 20,263 1,860,659 SH   DFND 2 213,838 0 1,646,821
Exscientia Ltd ADR ADS 30223G102 1,986 182,326 SH   DFND 3 182,326 0 0
Exscientia Ltd ADR ADS 30223G102 19,160 1,759,407 SH   SOLE 0 975,374 0 784,033
FTI Consulting COM 302941109 5,319 29,413 SH   SOLE 0 29,413 0 0
Factset Research Systems COM 303075105 23 61 SH   DFND 3 61 0 0
Farfetch ORD SHS CL A 30744W107 34,733 4,850,961 SH   DFND 1 4,850,961 0 0
Farfetch ORD SHS CL A 30744W107 116,570 16,280,796 SH   DFND 2 13,343,438 0 2,937,358
Farfetch ORD SHS CL A 30744W107 12,997 1,815,198 SH   DFND 3 1,184,263 0 630,935
Farfetch ORD SHS CL A 30744W107 85,069 11,881,112 SH   SOLE 0 7,271,109 0 4,610,003
Fastenal COM 311900104 77,276 1,547,989 SH   DFND 1 1,547,989 0 0
Fastenal COM 311900104 15,542 311,345 SH   DFND 2 239,961 0 71,384
Fastenal COM 311900104 14,630 293,068 SH   DFND 3 264,792 0 28,276
Fastenal COM 311900104 41,508 831,486 SH   SOLE 0 831,486 0 0
Fastly CL A 31188V100 2 205 SH   DFND 3 205 0 0
Fate Therapeutics COM 31189P102 9 372 SH   DFND 3 372 0 0
Ferrari NV COM N3167Y103 1,566,153 8,550,606 SH   DFND 2 6,777,804 0 1,772,802
Ferrari NV COM N3167Y103 249,087 1,359,921 SH   SOLE 0 1,359,921 0 0
Fibrogen Inc COM 31572Q808 5 467 SH   DFND 3 467 0 0
First Industrial REIT COM 32054K103 73,079 1,539,153 SH   DFND 1 1,539,153 0 0
First Industrial REIT COM 32054K103 128 2,703 SH   DFND 2 2,703 0 0
First Industrial REIT COM 32054K103 6,045 127,313 SH   DFND 3 127,313 0 0
First Republic Bank COM 33616C100 136,435 946,152 SH   DFND 1 946,152 0 0
First Republic Bank COM 33616C100 213,095 1,477,776 SH   DFND 2 1,435,569 0 42,207
First Republic Bank COM 33616C100 14,224 98,643 SH   DFND 3 84,536 0 14,107
First Republic Bank COM 33616C100 30,458 211,222 SH   SOLE 0 211,222 0 0
Fiverr Intl ORD SHS M4R82T106 6,847 199,100 SH   DFND 1 199,100 0 0
Fiverr Intl ORD SHS M4R82T106 5,929 172,400 SH   DFND 2 51,200 0 121,200
Fiverr Intl ORD SHS M4R82T106 2,305 67,019 SH   DFND 3 67,019 0 0
Fiverr Intl ORD SHS M4R82T106 6,489 188,700 SH   SOLE 0 188,700 0 0
Fortis COM 349553107 1,599 33,889 SH   DFND 1 33,889 0 0
Fortive Corp COM 34959J108 5,319 97,814 SH   DFND 2 97,814 0 0
Fox COM 35137L105 10 310 SH   DFND 3 310 0 0
Freshpet Inc COM 358039105 14 276 SH   DFND 2 276 0 0
Freshpet Inc COM 358039105 397 7,643 SH   DFND 3 7,643 0 0
Full Truck Alliance Co Ltd ADR SPONS ADS 35969L108 143,932 15,886,582 SH   DFND 2 15,436,948 0 449,634
Futu Hdgs ADR SPON ADR CL A 36118L106 57,863 1,108,279 SH   DFND 2 863,897 0 244,382
Futu Hdgs ADR SPON ADR CL A 36118L106 0 8 SH   DFND 4 8 0 0
GAN COM G3728V109 2 572 SH   DFND 3 572 0 0
Gentex Corp COM 371901109 14 516 SH   DFND 3 516 0 0
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 51,563 21,664,932 SH   DFND 1 21,664,932 0 0
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 157,429 66,146,772 SH   DFND 2 37,682,067 0 28,464,705
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 18,285 7,682,791 SH   DFND 3 6,298,562 0 1,384,229
Ginkgo Bioworks Holdings Inc CL A COM 37611X100 261,403 109,833,291 SH   SOLE 0 101,771,589 0 8,061,702
GitLab CLASS A 37637K108 4,480 84,315 SH   SOLE 0 84,315 0 0
Glaukos Corp COM 377322102 12 269 SH   DFND 3 269 0 0
Global Blood Therapeutics Inc COM 37890U108 27 835 SH   DFND 3 835 0 0
Globus Medical CL A 379577208 3,597 64,077 SH   SOLE 0 64,077 0 0
Golub Capital BDC Inc COM 38173M102 1,582 122,100 SH   DFND 1 122,100 0 0
Goodyear Tire & Rubber Co/The COM 382550101 15 1,400 SH   DFND 3 1,400 0 0
Graco COM 384109104 22 363 SH   DFND 3 363 0 0
Grainger, WW COM 384802104 27 60 SH   DFND 3 60 0 0
HDFC Bank ADR ADR REPS 3 SHS 40415F101 57,267 1,041,984 SH   DFND 2 896,760 0 145,224
HDFC Bank ADR ADR REPS 3 SHS 40415F101 10,792 196,355 SH   DFND 3 132,986 0 63,369
HDFC Bank ADR ADR REPS 3 SHS 40415F101 86,895 1,581,058 SH   SOLE 0 1,147,139 0 433,919
HUYA ADR ADS REP SHS A 44852D108 4,441 1,144,570 SH   DFND 1 1,144,570 0 0
HUYA ADR ADS REP SHS A 44852D108 2,410 621,141 SH   SOLE 0 621,141 0 0
Halozyme Therapeutics COM 40637H109 36 815 SH   DFND 3 815 0 0
Harris Corp COM 502431109 15 61 SH   DFND 3 61 0 0
Hashicorp Inc COM CL A 418100103 50,258 1,707,134 SH   DFND 1 1,707,134 0 0
Hashicorp Inc COM CL A 418100103 67,780 2,302,317 SH   DFND 2 2,131,399 0 170,918
Hashicorp Inc COM CL A 418100103 5,308 180,295 SH   DFND 3 180,295 0 0
Hashicorp Inc COM CL A 418100103 12,037 408,859 SH   SOLE 0 408,859 0 0
Health Catalyst Inc COM 42225T107 975 67,271 SH   DFND 1 67,271 0 0
Health Catalyst Inc COM 42225T107 2,192 151,258 SH   DFND 2 151,258 0 0
Health Catalyst Inc COM 42225T107 2,521 173,988 SH   DFND 3 173,988 0 0
Healthcare Services Group Inc COM 421906108 3 157 SH   DFND 3 157 0 0
Heron Therapeutics Inc COM 427746102 1 308 SH   DFND 3 308 0 0
Hershey Foods Corporation COM 427866108 15,964 74,198 SH   DFND 2 74,198 0 0
Hershey Foods Corporation COM 427866108 4,471 20,779 SH   SOLE 0 20,779 0 0
Hillenbrand COM 431571108 7 170 SH   DFND 3 170 0 0
Homology Medicines COM 438083107 1 481 SH   DFND 3 481 0 0
Howard Hughes COM 44267D107 27,595 405,518 SH   DFND 1 405,518 0 0
Howard Hughes COM 44267D107 81,612 1,199,301 SH   DFND 2 1,087,426 0 111,875
Howard Hughes COM 44267D107 16,409 241,132 SH   DFND 3 141,576 0 99,556
Howard Hughes COM 44267D107 74,984 1,101,896 SH   SOLE 0 717,371 0 384,525
Hubbell COM 443510607 16 87 SH   DFND 3 87 0 0
Hubspot Inc COM 443573100 39 131 SH   DFND 3 131 0 0
Humana COM 444859102 28 60 SH   DFND 3 60 0 0
Hutchison China Meditech SPONSORED ADR 44842L103 1,520 120,243 SH   DFND 1 120,243 0 0
Hutchison China Meditech SPONSORED ADR 44842L103 772 61,045 SH   DFND 2 365 0 60,680
Hutchison China Meditech SPONSORED ADR 44842L103 2,322 183,691 SH   DFND 3 102 0 183,589
ICICI Bank ADR ADR 45104G104 71,086 4,007,099 SH   DFND 1 4,007,099 0 0
ICICI Bank ADR ADR 45104G104 60,702 3,421,778 SH   DFND 2 3,421,778 0 0
ICICI Bank ADR ADR 45104G104 11,904 671,046 SH   DFND 3 671,046 0 0
ICICI Bank ADR ADR 45104G104 4,265 240,440 SH   DFND 4 240,440 0 0
IPG Photonics Corp COM 44980X109 11,366 120,747 SH   DFND 1 120,747 0 0
IPG Photonics Corp COM 44980X109 10,312 109,549 SH   DFND 2 33,281 0 76,268
IPG Photonics Corp COM 44980X109 4,652 49,416 SH   DFND 3 49,416 0 0
IPG Photonics Corp COM 44980X109 8,503 90,336 SH   SOLE 0 90,336 0 0
Iac/Interactivecorp COM 44891N208 16,632 218,935 SH   DFND 1 218,935 0 0
Iac/Interactivecorp COM 44891N208 49,174 647,278 SH   DFND 2 587,612 0 59,666
Iac/Interactivecorp COM 44891N208 10,235 134,727 SH   DFND 3 80,028 0 54,699
Iac/Interactivecorp COM 44891N208 43,854 577,251 SH   SOLE 0 370,323 0 206,928
Ii-Vi Inc COM 902104108 24 477 SH   DFND 3 477 0 0
Illumina COM 452327109 380,334 2,062,997 SH   DFND 1 2,062,997 0 0
Illumina COM 452327109 1,980,787 10,744,127 SH   DFND 2 7,840,329 0 2,903,798
Illumina COM 452327109 241,320 1,308,959 SH   DFND 3 1,019,748 0 289,211
Illumina COM 452327109 1,074,002 5,825,570 SH   SOLE 0 4,833,829 0 991,741
InMode SHS M5425M103 13 596 SH   DFND 3 596 0 0
Incyte Corp COM 45337C102 13 165 SH   DFND 3 165 0 0
Infinera COM 45667G103 16 2,941 SH   DFND 3 2,941 0 0
Infosys Ltd ADR SPONSORED ADR 456788108 21,579 1,165,809 SH   DFND 1 1,165,809 0 0
Infosys Ltd ADR SPONSORED ADR 456788108 19,021 1,027,594 SH   DFND 2 111,463 0 916,131
Infosys Ltd ADR SPONSORED ADR 456788108 25,314 1,367,593 SH   DFND 3 529,257 0 838,336
Infosys Ltd ADR SPONSORED ADR 456788108 3,232 174,620 SH   DFND 4 174,620 0 0
Inogen Inc COM 45780L104 3 141 SH   DFND 3 141 0 0
Insmed Inc COM 457669307 14 707 SH   DFND 3 707 0 0
Inspire Medical Systems COM 457730109 32 173 SH   DFND 3 173 0 0
Intercept Pharmaceuticals Inc COM 45845P108 1 101 SH   DFND 3 101 0 0
International Game Technology SHS G4863A108 19 1,024 SH   DFND 3 1,024 0 0
Intuit COM 461202103 20,070 52,071 SH   DFND 1 52,071 0 0
Intuit COM 461202103 200 518 SH   DFND 2 0 0 518
Intuit COM 461202103 2,776 7,201 SH   DFND 3 7,201 0 0
Intuit COM 461202103 11,366 29,489 SH   SOLE 0 29,489 0 0
Intuitive Surgical COM NEW 46120E602 77,817 387,707 SH   DFND 1 387,707 0 0
Intuitive Surgical COM NEW 46120E602 519,291 2,587,271 SH   DFND 2 982,165 0 1,605,106
Intuitive Surgical COM NEW 46120E602 80,222 399,693 SH   DFND 3 318,285 0 81,408
Intuitive Surgical COM NEW 46120E602 164,089 817,545 SH   SOLE 0 354,708 0 462,837
Invitae COM 46185L103 2 800 SH   DFND 3 800 0 0
Ionis Pharmaceuticals COM 462222100 2,034 54,949 SH   DFND 1 54,949 0 0
Ionis Pharmaceuticals COM 462222100 4,340 117,222 SH   DFND 2 117,222 0 0
Ionis Pharmaceuticals COM 462222100 5,140 138,844 SH   DFND 3 138,844 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 10,319 2,410,946 SH   DFND 1 2,410,946 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 29,912 6,988,859 SH   DFND 2 485,582 0 6,503,277
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 38,112 8,904,694 SH   DFND 3 827,941 0 8,076,753
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 1,649 385,212 SH   DFND 4 385,212 0 0
Ivanhoe Mines COM CL A 46579R104 8 1,400 SH   DFND 2 1,400 0 0
J&J Snack Foods Corp COM 466032109 12 83 SH   DFND 3 83 0 0
JD.Com Inc - ADR SPON ADR CL A 47215P106 0 1 SH   DFND 4 1 0 0
JDS Uniphase Corporation COM 925550105 15 1,142 SH   DFND 3 1,142 0 0
JFrog Ltd ORD SHS M6191J100 12,746 604,939 SH   DFND 1 604,939 0 0
JFrog Ltd ORD SHS M6191J100 8,972 425,802 SH   DFND 2 128,870 0 296,932
JFrog Ltd ORD SHS M6191J100 4,223 200,422 SH   DFND 3 200,422 0 0
JFrog Ltd ORD SHS M6191J100 8,725 414,081 SH   SOLE 0 414,081 0 0
Jack Henry & Associates COM 426281101 11 62 SH   DFND 3 62 0 0
Jazz Pharmaceuticals SHS G50871105 26 168 SH   DFND 3 168 0 0
Joby Aviation Inc COM G65163100 37,695 7,677,200 SH   SOLE 0 7,677,200 0 0
Johnson & Johnson COM 478160104 18 99 SH   DFND 3 99 0 0
Jumia Technologies Ag ADR SPONSORED ADS 48138M105 57,255 9,447,992 SH   DFND 2 8,765,497 0 682,495
Jumia Technologies Ag ADR SPONSORED ADS 48138M105 2,631 434,078 SH   DFND 3 374 0 433,704
KE Holdings ADR ADR 482497104 8,934 497,723 SH   DFND 1 497,723 0 0
KE Holdings ADR ADR 482497104 19,946 1,111,204 SH   DFND 2 579,688 0 531,516
KE Holdings ADR ADR 482497104 195 10,854 SH   DFND 3 10,854 0 0
KE Holdings ADR ADR 482497104 869 48,406 SH   SOLE 0 48,406 0 0
KFORCE INC. COM 493732101 18 295 SH   DFND 3 295 0 0
Kingsoft Cloud Holdings Ltd ADR SPON ADR 49639K101 3,531 793,536 SH   DFND 2 793,536 0 0
Knowles Corp COM 49926D109 21 1,200 SH   DFND 3 1,200 0 0
Kulicke & Soffa Industries Inc COM 501242101 21 491 SH   DFND 3 491 0 0
Lemonade Inc COM 52567D107 29,065 1,591,709 SH   DFND 1 1,591,709 0 0
Lemonade Inc COM 52567D107 43,468 2,380,478 SH   DFND 2 2,357,419 0 23,059
Lemonade Inc COM 52567D107 1,705 93,391 SH   DFND 3 93,391 0 0
Lemonade Inc COM 52567D107 18,590 1,018,079 SH   SOLE 0 1,018,079 0 0
LendingTree COM 52603B107 9,933 226,675 SH   DFND 1 226,675 0 0
LendingTree COM 52603B107 9,320 212,691 SH   DFND 2 66,189 0 146,502
LendingTree COM 52603B107 4,447 101,492 SH   DFND 3 95,659 0 5,833
LendingTree COM 52603B107 5,249 119,788 SH   SOLE 0 119,788 0 0
Li Auto ADR SPONS ADS 50202M102 66,470 1,735,052 SH   DFND 1 1,735,052 0 0
Li Auto ADR SPONS ADS 50202M102 203,084 5,301,066 SH   DFND 2 4,809,965 0 491,101
Li Auto ADR SPONS ADS 50202M102 40,469 1,056,369 SH   DFND 3 617,176 0 439,193
Li Auto ADR SPONS ADS 50202M102 182,585 4,766,001 SH   SOLE 0 3,135,607 0 1,630,394
Liberty Broadband Corp COM 530307305 8 70 SH   DFND 3 70 0 0
Lightspeed POS COM 53229C107 7 310 SH   DFND 3 310 0 0
Lilium N.V. CL A COM N52586109 22 9,151 SH   DFND 1 9,151 0 0
Lilium N.V. CL A COM N52586109 2,641 1,118,923 SH   DFND 2 1,118,923 0 0
Lilium N.V. CL A COM N52586109 41,771 17,699,615 SH   SOLE 0 17,699,615 0 0
Lincoln Electric Holdings Inc COM 533900106 11 91 SH   DFND 3 91 0 0
LivePerson Inc COM 538146101 6,067 429,091 SH   DFND 1 429,091 0 0
LivePerson Inc COM 538146101 5,123 362,307 SH   DFND 2 109,647 0 252,660
LivePerson Inc COM 538146101 2,013 142,393 SH   DFND 3 142,393 0 0
LivePerson Inc COM 538146101 3,505 247,880 SH   SOLE 0 247,880 0 0
Liveramp Holdings Inc COM 53815P108 15,883 615,401 SH   DFND 1 615,401 0 0
Liveramp Holdings Inc COM 53815P108 8,097 313,729 SH   DFND 2 96,483 0 217,246
Liveramp Holdings Inc COM 53815P108 4,125 159,816 SH   DFND 3 159,816 0 0
Liveramp Holdings Inc COM 53815P108 7,616 295,075 SH   SOLE 0 295,075 0 0
Logitech International SA SHS H50430232 13 235 SH   DFND 3 235 0 0
Lufax Holding Ltd COM 54975P102 43,470 7,245,015 SH   DFND 1 7,245,015 0 0
Lufax Holding Ltd COM 54975P102 105,471 17,578,530 SH   DFND 2 9,992,995 0 7,585,535
Lufax Holding Ltd COM 54975P102 1,033 172,168 SH   DFND 3 172,168 0 0
Lyell Immunopharma Inc COM 55083R104 793 121,571 SH   DFND 1 121,571 0 0
Lyell Immunopharma Inc COM 55083R104 1,814 278,187 SH   DFND 2 278,187 0 0
Lyell Immunopharma Inc COM 55083R104 2,008 307,907 SH   DFND 3 307,907 0 0
Lyft Inc Class A Common CL A COM 55087P104 16 1,228 SH   DFND 3 1,228 0 0
M&T Bank Corp COM 55261F104 3,938 24,709 SH   SOLE 0 24,709 0 0
MELI Kaszek Pioneer CL A COM G5S74L106 19,800 2,000,000 SH   DFND 2 2,000,000 0 0
MP Materials COM CL A 553368101 60,779 1,894,600 SH   DFND 1 1,894,600 0 0
MP Materials COM CL A 553368101 78 2,430 SH   DFND 2 2,430 0 0
MP Materials COM CL A 553368101 3,420 106,600 SH   DFND 3 106,600 0 0
MakeMyTrip SHS V5633W109 67,236 2,618,235 SH   DFND 2 1,955,224 0 663,011
Marathon Digital Holdings COM 565788106 2 343 SH   DFND 3 343 0 0
Markel Corp COM 570535104 63,398 49,022 SH   DFND 1 49,022 0 0
Markel Corp COM 570535104 203,364 157,250 SH   DFND 2 143,139 0 14,111
Markel Corp COM 570535104 37,878 29,289 SH   DFND 3 17,228 0 12,061
Markel Corp COM 570535104 183,166 141,632 SH   SOLE 0 95,006 0 46,626
MarketAxess Holdings COM 57060D108 124,037 484,501 SH   DFND 1 484,501 0 0
MarketAxess Holdings COM 57060D108 174,848 682,973 SH   DFND 2 545,500 0 137,473
MarketAxess Holdings COM 57060D108 27,890 108,943 SH   DFND 3 99,836 0 9,107
MarketAxess Holdings COM 57060D108 49,027 191,506 SH   SOLE 0 191,506 0 0
Martin Marietta Materials COM 573284106 153,730 513,735 SH   DFND 1 513,735 0 0
Martin Marietta Materials COM 573284106 510,614 1,706,370 SH   DFND 2 1,553,996 0 152,374
Martin Marietta Materials COM 573284106 82,740 276,502 SH   DFND 3 159,383 0 117,119
Martin Marietta Materials COM 573284106 329,104 1,099,799 SH   SOLE 0 758,922 0 340,877
Masimo Corp COM 574795100 2,044 15,646 SH   DFND 1 15,646 0 0
Masimo Corp COM 574795100 4,414 33,780 SH   DFND 2 33,780 0 0
Masimo Corp COM 574795100 5,233 40,046 SH   DFND 3 40,046 0 0
Mastercard Inc-Class A CL A 57636Q104 120,316 381,375 SH   DFND 1 381,375 0 0
Mastercard Inc-Class A CL A 57636Q104 389,343 1,234,128 SH   DFND 2 1,125,446 0 108,682
Mastercard Inc-Class A CL A 57636Q104 72,402 229,498 SH   DFND 3 136,056 0 93,442
Mastercard Inc-Class A CL A 57636Q104 320,116 1,014,696 SH   SOLE 0 656,241 0 358,455
Materialise Nv ADR SPONSORED ADS 57667T100 3,650 268,000 SH   DFND 2 268,000 0 0
Maxlinear Inc COM 57776J100 14 405 SH   DFND 3 405 0 0
McDonald's COM 580135101 18,760 75,990 SH   DFND 1 75,990 0 0
McDonald's COM 580135101 350 1,416 SH   DFND 2 0 0 1,416
McDonald's COM 580135101 742 3,007 SH   DFND 3 3,007 0 0
McDonald's COM 580135101 20,395 82,612 SH   SOLE 0 82,612 0 0
Medifast Inc COM 58470H101 24 133 SH   DFND 3 133 0 0
Medtronic COM G5960L103 22,002 245,150 SH   DFND 1 245,150 0 0
Medtronic COM G5960L103 224 2,494 SH   DFND 2 0 0 2,494
Medtronic COM G5960L103 3,000 33,422 SH   DFND 3 33,422 0 0
Medtronic COM G5960L103 12,572 140,079 SH   SOLE 0 140,079 0 0
MercadoLibre COM 58733R102 228,251 358,395 SH   DFND 1 358,395 0 0
MercadoLibre COM 58733R102 2,734,412 4,293,516 SH   DFND 2 3,411,984 0 881,532
MercadoLibre COM 58733R102 142,079 223,089 SH   DFND 3 182,780 0 40,309
MercadoLibre COM 58733R102 5,705 8,958 SH   DFND 4 8,958 0 0
MercadoLibre COM 58733R102 345,164 541,969 SH   SOLE 0 514,119 0 27,850
Meta Platforms Inc CL A 30303M102 121,888 755,894 SH   DFND 1 755,894 0 0
Meta Platforms Inc CL A 30303M102 630,232 3,908,416 SH   DFND 2 2,056,413 0 1,852,003
Meta Platforms Inc CL A 30303M102 103,014 638,848 SH   DFND 3 466,000 0 172,848
Meta Platforms Inc CL A 30303M102 298,363 1,850,316 SH   SOLE 0 1,016,120 0 834,196
Mettler-Toledo COM 592688105 86,761 75,525 SH   DFND 1 75,525 0 0
Mettler-Toledo COM 592688105 340,276 296,209 SH   DFND 2 221,330 0 74,879
Mettler-Toledo COM 592688105 3,604 3,137 SH   DFND 3 3,137 0 0
Mettler-Toledo COM 592688105 29,526 25,702 SH   SOLE 0 25,702 0 0
Microsoft COM 594918104 262,487 1,022,026 SH   DFND 1 1,022,026 0 0
Microsoft COM 594918104 656,060 2,554,451 SH   DFND 2 2,339,243 0 215,208
Microsoft COM 594918104 127,309 495,695 SH   DFND 3 307,412 0 188,283
Microsoft COM 594918104 569,922 2,219,063 SH   SOLE 0 1,491,149 0 727,914
Mirati Therapeutics COM 60468T105 13 196 SH   DFND 3 196 0 0
Mobile Telesystems ADR SPONSORED ADR 607409109 0 42,174 SH   DFND 1 42,174 0 0
Moderna Inc COM 60770K107 689,520 4,826,880 SH   DFND 1 4,826,880 0 0
Moderna Inc COM 60770K107 3,524,631 24,673,648 SH   DFND 2 19,439,565 0 5,234,083
Moderna Inc COM 60770K107 372,158 2,605,239 SH   DFND 3 2,045,498 0 559,741
Moderna Inc COM 60770K107 1,921,907 13,454,024 SH   SOLE 0 11,687,448 0 1,766,576
Momentive Global Inc COM 60878Y108 10 1,095 SH   DFND 3 1,095 0 0
MongoDB Inc COM 60937P106 55 213 SH   DFND 3 213 0 0
MongoDB Inc COM 60937P106 880 3,393 SH   SOLE 0 3,393 0 0
Monolithic Power Systems Inc COM 609839105 24 63 SH   DFND 3 63 0 0
Moody's Corp COM 615369105 172,322 633,605 SH   DFND 1 633,605 0 0
Moody's Corp COM 615369105 557,421 2,049,567 SH   DFND 2 1,867,185 0 182,382
Moody's Corp COM 615369105 105,351 387,361 SH   DFND 3 227,137 0 160,224
Moody's Corp COM 615369105 470,733 1,730,827 SH   SOLE 0 1,109,241 0 621,586
NIO Inc ADR SPON ADS 62914V106 63,346 2,916,485 SH   DFND 1 2,916,485 0 0
NIO Inc ADR SPON ADS 62914V106 1,351,291 62,214,136 SH   DFND 2 46,897,006 0 15,317,130
NIO Inc ADR SPON ADS 62914V106 64,984 2,991,884 SH   DFND 3 2,380,693 0 611,191
NIO Inc ADR SPON ADS 62914V106 621,380 28,608,634 SH   SOLE 0 25,144,374 0 3,464,260
NV5 Global COM 62945V109 18 155 SH   DFND 3 155 0 0
NVIDIA COM 67066G104 309,014 2,038,483 SH   DFND 1 2,038,483 0 0
NVIDIA COM 67066G104 1,246,384 8,222,075 SH   DFND 2 4,185,541 0 4,036,534
NVIDIA COM 67066G104 162,253 1,070,344 SH   DFND 3 860,763 0 209,581
NVIDIA COM 67066G104 602,322 3,973,360 SH   SOLE 0 2,877,411 0 1,095,949
Nano Dimension ADR SPONS ADS 63008G203 5 1,600 SH   DFND 3 1,600 0 0
Nanobiotix ADR COM 63009J107 3,276 850,841 SH   DFND 1 850,841 0 0
Nanobiotix ADR COM 63009J107 2,114 549,159 SH   SOLE 0 549,159 0 0
National Instruments Corp COM 636518102 26,357 843,961 SH   DFND 1 843,961 0 0
National Instruments Corp COM 636518102 251 8,049 SH   DFND 2 0 0 8,049
National Instruments Corp COM 636518102 3,855 123,427 SH   DFND 3 123,427 0 0
National Instruments Corp COM 636518102 14,374 460,267 SH   SOLE 0 460,267 0 0
Nektar Therapeutics COM 640268108 5 1,376 SH   DFND 3 1,376 0 0
NetEase.com ADR SPONSORED ADR 64110W102 9,648 103,340 SH   DFND 2 0 0 103,340
Netflix Inc COM 64110L106 207,797 1,188,294 SH   DFND 1 1,188,294 0 0
Netflix Inc COM 64110L106 645,378 3,690,617 SH   DFND 2 2,229,665 0 1,460,952
Netflix Inc COM 64110L106 84,061 480,708 SH   DFND 3 375,585 0 105,123
Netflix Inc COM 64110L106 369,659 2,113,909 SH   SOLE 0 1,603,702 0 510,207
Nevro Corp COM 64157F103 7 154 SH   DFND 3 154 0 0
New Relic COM 64829B100 37 733 SH   DFND 3 733 0 0
Newmont Mining COM 651639106 1,204 20,172 SH   DFND 1 20,172 0 0
Newmont Mining COM 651639106 156 2,615 SH   DFND 2 2,615 0 0
NextEra Energy COM 65339F101 40,585 523,943 SH   DFND 1 523,943 0 0
NextEra Energy COM 65339F101 72 927 SH   DFND 2 927 0 0
NextEra Energy COM 65339F101 2,832 36,559 SH   DFND 3 36,559 0 0
Nike COM 654106103 9 90 SH   DFND 3 90 0 0
Novanta Inc COM 67000B104 32 264 SH   DFND 2 264 0 0
Novanta Inc COM 67000B104 888 7,322 SH   DFND 3 7,322 0 0
Novavax Inc COM NEW 670002401 7 130 SH   DFND 3 130 0 0
Novocure Ltd ORD SHS G6674U108 174,097 2,504,992 SH   DFND 1 2,504,992 0 0
Novocure Ltd ORD SHS G6674U108 281,702 4,053,266 SH   DFND 2 3,574,283 0 478,983
Novocure Ltd ORD SHS G6674U108 44,396 638,789 SH   DFND 3 527,847 0 110,942
Novocure Ltd ORD SHS G6674U108 133,383 1,919,183 SH   SOLE 0 1,498,350 0 420,833
Nu Holdings Ltd. ORD SHS CL A G6683N103 23,146 6,188,749 SH   DFND 1 6,188,749 0 0
Nu Holdings Ltd. ORD SHS CL A G6683N103 58,443 15,626,543 SH   DFND 2 13,407,281 0 2,219,262
Nu Holdings Ltd. ORD SHS CL A G6683N103 23,477 6,277,327 SH   DFND 3 4,937,946 0 1,339,381
Nu Holdings Ltd. ORD SHS CL A G6683N103 5,646 1,509,738 SH   SOLE 0 575,423 0 934,315
Nucana Plc ADR SPONSORED ADR 67022C106 1,755 2,420,041 SH   DFND 1 2,420,041 0 0
Nucana Plc ADR SPONSORED ADR 67022C106 898 1,238,989 SH   SOLE 0 1,238,989 0 0
Nutanix Inc COM 67059N108 8 563 SH   DFND 3 563 0 0
Oatly Inc. SPONS ADS 67421J108 127,154 36,749,580 SH   DFND 2 30,647,472 0 6,102,108
Oatly Inc. SPONS ADS 67421J108 3,674 1,061,969 SH   SOLE 0 1,061,969 0 0
On Semiconductor Corp COM 682189105 29 575 SH   DFND 3 575 0 0
Opko Health Inc COM 68375N103 17 6,635 SH   DFND 3 6,635 0 0
Oscar Health Inc COM 687793109 12,054 2,836,131 SH   DFND 1 2,836,131 0 0
Oscar Health Inc COM 687793109 34,657 8,154,518 SH   DFND 2 7,413,648 0 740,870
Oscar Health Inc COM 687793109 7,619 1,792,770 SH   DFND 3 1,099,126 0 693,644
Oscar Health Inc COM 687793109 34,009 8,002,211 SH   SOLE 0 5,534,774 0 2,467,437
Outset Medical COM 690145107 5 306 SH   DFND 3 306 0 0
Oxford Industries Inc COM 691497309 5 55 SH   DFND 3 55 0 0
Ozon Holdings ADR COM 69269L104 0 333,970 SH   DFND 1 333,970 0 0
Ozon Holdings ADR COM 69269L104 0 2,478,153 SH   DFND 2 1,319,308 0 1,158,845
Ozon Holdings ADR COM 69269L104 0 19,278 SH   DFND 3 19,278 0 0
PROCEPT BioRobotics COM 74276L105 12 376 SH   DFND 3 376 0 0
Paccar COM 693718108 3,513 42,668 SH   SOLE 0 42,668 0 0
Pacira BioSciences COM 695127100 40,484 694,400 SH   DFND 1 694,400 0 0
Pacira BioSciences COM 695127100 33,178 569,090 SH   DFND 2 188,049 0 381,041
Pacira BioSciences COM 695127100 19,310 331,223 SH   DFND 3 287,036 0 44,187
Pacira BioSciences COM 695127100 19,824 340,039 SH   SOLE 0 340,039 0 0
PagerDuty COM 69553P100 14 565 SH   DFND 3 565 0 0
Pagseguro Digital Ltd COM CL A G68707101 2 148 SH   DFND 2 148 0 0
Pagseguro Digital Ltd COM CL A G68707101 985 96,176 SH   DFND 3 96,176 0 0
Paychex COM 704326107 13 116 SH   DFND 3 116 0 0
Peloton Interactive Inc CL A COM 70614W100 43,984 4,791,320 SH   DFND 1 4,791,320 0 0
Peloton Interactive Inc CL A COM 70614W100 144,403 15,730,207 SH   DFND 2 8,058,474 0 7,671,733
Peloton Interactive Inc CL A COM 70614W100 24,968 2,719,794 SH   DFND 3 2,180,899 0 538,895
Peloton Interactive Inc CL A COM 70614W100 39,684 4,322,897 SH   SOLE 0 2,067,376 0 2,255,521
Penumbra Inc COM 70975L107 58,782 472,071 SH   DFND 1 472,071 0 0
Penumbra Inc COM 70975L107 83,437 670,071 SH   DFND 2 663,532 0 6,539
Penumbra Inc COM 70975L107 3,613 29,016 SH   DFND 3 29,016 0 0
Penumbra Inc COM 70975L107 12,715 102,116 SH   SOLE 0 102,116 0 0
Pepsico COM 713448108 61,373 368,252 SH   DFND 1 368,252 0 0
Pepsico COM 713448108 578 3,468 SH   DFND 2 0 0 3,468
Pepsico COM 713448108 8,941 53,646 SH   DFND 3 53,646 0 0
Pepsico COM 713448108 33,518 201,118 SH   SOLE 0 201,118 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 166,869 14,286,702 SH   DFND 1 14,286,702 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 536,278 45,914,243 SH   DFND 2 23,372,010 0 22,542,233
Petrobras Common ADR SPONSORED ADR 71654V408 21,443 1,835,913 SH   DFND 3 1,835,913 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 8,423 721,118 SH   DFND 4 721,118 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 8,641 739,803 SH   SOLE 0 739,803 0 0
Petrobras Pref ADR SP ADR NON VTG 71654V101 15,036 1,414,518 SH   DFND 1 1,414,518 0 0
Petrobras Pref ADR SP ADR NON VTG 71654V101 90,642 8,527,009 SH   DFND 2 6,304,501 0 2,222,508
Petrobras Pref ADR SP ADR NON VTG 71654V101 794 74,696 SH   DFND 3 74,696 0 0
Pfizer COM 717081103 26 500 SH   DFND 3 500 0 0
Piedmont Lithium Inc COM 72016P105 8 212 SH   DFND 3 212 0 0
Pinduoduo Inc ADR SPONSORED ADS 722304102 115,981 1,876,715 SH   DFND 1 1,876,715 0 0
Pinduoduo Inc ADR SPONSORED ADS 722304102 985,402 15,945,018 SH   DFND 2 8,252,687 0 7,692,331
Pinduoduo Inc ADR SPONSORED ADS 722304102 114,935 1,859,788 SH   DFND 3 1,484,657 0 375,131
Pinduoduo Inc ADR SPONSORED ADS 722304102 520,268 8,418,583 SH   SOLE 0 6,294,604 0 2,123,979
Pinterest COM 72352L106 40,717 2,242,117 SH   DFND 1 2,242,117 0 0
Pinterest COM 72352L106 62,396 3,435,914 SH   DFND 2 3,403,508 0 32,406
Pinterest COM 72352L106 2,446 134,692 SH   DFND 3 134,692 0 0
Pinterest COM 72352L106 9,444 520,071 SH   SOLE 0 520,071 0 0
Precision BioSciences Inc COM 74019P108 3 2,133 SH   DFND 2 2,133 0 0
Precision BioSciences Inc COM 74019P108 91 56,678 SH   DFND 3 56,678 0 0
Procter & Gamble COM 742718109 68,416 475,804 SH   DFND 1 475,804 0 0
Procter & Gamble COM 742718109 639 4,447 SH   DFND 2 0 0 4,447
Procter & Gamble COM 742718109 9,991 69,480 SH   DFND 3 69,480 0 0
Procter & Gamble COM 742718109 38,025 264,451 SH   SOLE 0 264,451 0 0
Progressive COM 743315103 3,924 33,746 SH   SOLE 0 33,746 0 0
Progyny COM 74340E103 17,125 589,485 SH   DFND 1 589,485 0 0
Progyny COM 74340E103 15,678 539,689 SH   DFND 2 173,604 0 366,085
Progyny COM 74340E103 8,243 283,761 SH   DFND 3 254,097 0 29,664
Progyny COM 74340E103 6,720 231,309 SH   SOLE 0 231,309 0 0
Prologis Inc REIT COM 74340W103 73,086 621,218 SH   DFND 1 621,218 0 0
Prologis Inc REIT COM 74340W103 122 1,034 SH   DFND 2 1,034 0 0
Prologis Inc REIT COM 74340W103 5,842 49,659 SH   DFND 3 49,659 0 0
Proterra Inc COM 74374T109 54 11,566 SH   DFND 1 11,566 0 0
Ptc Therapeutics Inc COM 69366J200 10 246 SH   DFND 3 246 0 0
Pure Storage Inc COM 74624M102 34 1,335 SH   DFND 3 1,335 0 0
Q2 Holdings Inc COM 74736L109 12,279 318,346 SH   DFND 1 318,346 0 0
Q2 Holdings Inc COM 74736L109 7,065 183,184 SH   DFND 2 56,237 0 126,947
Q2 Holdings Inc COM 74736L109 3,474 90,058 SH   DFND 3 90,058 0 0
Q2 Holdings Inc COM 74736L109 4,715 122,235 SH   SOLE 0 122,235 0 0
Qualcomm COM 747525103 23 183 SH   DFND 3 183 0 0
Quanterix Corp COM 74766Q101 6,332 391,135 SH   DFND 1 391,135 0 0
Quanterix Corp COM 74766Q101 17 1,045 SH   DFND 2 1,045 0 0
Quanterix Corp COM 74766Q101 470 29,013 SH   DFND 3 29,013 0 0
Quanterix Corp COM 74766Q101 3,395 209,677 SH   SOLE 0 209,677 0 0
QuantumScape Corp COM CL A 74767V109 26 3,002 SH   DFND 1 3,002 0 0
QuantumScape Corp COM CL A 74767V109 7,845 913,279 SH   SOLE 0 913,279 0 0
Quest Diagnostics COM 74834L100 19 145 SH   DFND 3 145 0 0
Quidel Corp COM 219798105 12 128 SH   DFND 3 128 0 0
REGENXBIO COM 75901B107 19 752 SH   DFND 3 752 0 0
Rambus Inc COM 750917106 14 630 SH   DFND 3 630 0 0
Recursion Pharmaceuticals Inc CL A 75629V104 21,673 2,662,543 SH   DFND 1 2,662,543 0 0
Recursion Pharmaceuticals Inc CL A 75629V104 31,521 3,872,304 SH   DFND 2 3,836,239 0 36,065
Recursion Pharmaceuticals Inc CL A 75629V104 4,110 504,853 SH   DFND 3 504,853 0 0
Recursion Pharmaceuticals Inc CL A 75629V104 118,567 14,565,985 SH   SOLE 0 14,565,985 0 0
Redfin COM 75737F108 30,605 3,714,187 SH   DFND 1 3,714,187 0 0
Redfin COM 75737F108 42,449 5,151,612 SH   DFND 2 5,014,508 0 137,104
Redfin COM 75737F108 3,129 379,784 SH   DFND 3 338,187 0 41,597
Redfin COM 75737F108 6,180 750,021 SH   SOLE 0 750,021 0 0
Regeneron Pharmaceuticals COM 75886F107 30 50 SH   DFND 3 50 0 0
Relay Therapeutics Inc COM 75943R102 635 37,930 SH   DFND 1 37,930 0 0
Relay Therapeutics Inc COM 75943R102 1,385 82,714 SH   DFND 2 82,714 0 0
Relay Therapeutics Inc COM 75943R102 1,658 98,978 SH   DFND 3 98,978 0 0
ResMed COM 761152107 2,669 12,734 SH   DFND 1 12,734 0 0
ResMed COM 761152107 5,777 27,556 SH   DFND 2 27,556 0 0
ResMed COM 761152107 6,765 32,269 SH   DFND 3 32,269 0 0
Research in Motion COM 09228F103 13 2,434 SH   DFND 3 2,434 0 0
Rexford Industrial Realty REIT COM 76169C100 91,930 1,596,281 SH   DFND 1 1,596,281 0 0
Rexford Industrial Realty REIT COM 76169C100 165 2,866 SH   DFND 2 2,866 0 0
Rexford Industrial Realty REIT COM 76169C100 7,864 136,543 SH   DFND 3 136,543 0 0
Rio Tinto Spn.Adr 1:1 SPONSORED ADR 767204100 2 38 SH   DFND 4 38 0 0
Ritchie Bros Auctioneers (USA) COM 767744105 104,831 1,611,301 SH   DFND 2 1,474,243 0 137,058
Ritchie Bros Auctioneers (USA) COM 767744105 1 21 SH   DFND 4 21 0 0
Ritchie Bros. Auctioneers COM 767744105 73,891 1,138,092 SH   DFND 2 673,786 0 464,306
Rivian Automotive Inc COM CL A 76954A103 31,223 1,213,033 SH   DFND 1 1,213,033 0 0
Rivian Automotive Inc COM CL A 76954A103 46,624 1,811,360 SH   DFND 2 1,793,741 0 17,619
Rivian Automotive Inc COM CL A 76954A103 1,929 74,942 SH   DFND 3 74,942 0 0
Rivian Automotive Inc COM CL A 76954A103 7,721 299,948 SH   SOLE 0 299,948 0 0
Robert Half International Inc COM 770323103 10 131 SH   DFND 3 131 0 0
Roblox CL A 771049103 66,044 2,009,867 SH   DFND 1 2,009,867 0 0
Roblox CL A 771049103 290,550 8,842,051 SH   DFND 2 4,100,163 0 4,741,888
Roblox CL A 771049103 40,728 1,239,439 SH   DFND 3 1,000,891 0 238,548
Roblox CL A 771049103 88,448 2,691,659 SH   SOLE 0 1,326,728 0 1,364,931
Roku COM CL A 77543R102 102,350 1,246,038 SH   DFND 1 1,246,038 0 0
Roku COM CL A 77543R102 151,436 1,843,632 SH   DFND 2 1,825,639 0 17,993
Roku COM CL A 77543R102 6,230 75,849 SH   DFND 3 75,849 0 0
Roku COM CL A 77543R102 22,729 276,707 SH   SOLE 0 276,707 0 0
Rollins Inc COM 775711104 20 562 SH   DFND 3 562 0 0
Royalty Pharma SHS CLASS A G7709Q104 100,132 2,381,823 SH   DFND 1 2,381,823 0 0
Royalty Pharma SHS CLASS A G7709Q104 319,456 7,598,867 SH   DFND 2 6,899,866 0 699,001
Royalty Pharma SHS CLASS A G7709Q104 61,283 1,457,742 SH   DFND 3 849,118 0 608,624
Royalty Pharma SHS CLASS A G7709Q104 275,635 6,556,486 SH   SOLE 0 4,266,270 0 2,290,216
Rubius Therapeutics Inc COM 78116T103 755 887,000 SH   DFND 1 887,000 0 0
Rubius Therapeutics Inc COM 78116T103 239 280,797 SH   DFND 2 79,171 0 201,626
Rubius Therapeutics Inc COM 78116T103 130 152,722 SH   DFND 3 152,722 0 0
Rubius Therapeutics Inc COM 78116T103 3,050 3,585,559 SH   SOLE 0 3,585,559 0 0
Ryanair ADR SPONSORED ADR NE 783513203 17,549 260,957 SH   DFND 1 260,957 0 0
Ryanair ADR SPONSORED ADR NE 783513203 619,731 9,215,330 SH   DFND 2 8,038,651 0 1,176,679
Ryanair ADR SPONSORED ADR NE 783513203 5,853 87,037 SH   DFND 3 87,037 0 0
Ryanair ADR SPONSORED ADR NE 783513203 3 40 SH   DFND 4 40 0 0
Ryanair ADR SPONSORED ADR NE 783513203 8,217 122,188 SH   SOLE 0 115,045 0 7,143
S&P Global Inc COM 78409V104 74,536 221,135 SH   DFND 1 221,135 0 0
S&P Global Inc COM 78409V104 242,550 719,606 SH   DFND 2 656,937 0 62,669
S&P Global Inc COM 78409V104 45,477 134,924 SH   DFND 3 79,496 0 55,428
S&P Global Inc COM 78409V104 207,419 615,377 SH   SOLE 0 401,918 0 213,459
SCP Pool Corporation COM 73278L105 25 70 SH   DFND 3 70 0 0
SEA Ltd ADR ADR 81141R100 168,587 2,521,492 SH   DFND 1 2,521,492 0 0
SEA Ltd ADR ADR 81141R100 713,441 10,670,668 SH   DFND 2 8,023,201 0 2,647,467
SEA Ltd ADR ADR 81141R100 53,419 798,973 SH   DFND 3 554,228 0 244,745
SEA Ltd ADR ADR 81141R100 973 14,559 SH   DFND 4 14,559 0 0
SEA Ltd ADR ADR 81141R100 194,836 2,914,085 SH   SOLE 0 1,842,077 0 1,072,008
SKYWORKS SOLUTIONS, INC. COM 83088M102 13 136 SH   DFND 3 136 0 0
Sage Therapeutics Inc COM 78667J108 500 15,465 SH   DFND 1 15,465 0 0
Sage Therapeutics Inc COM 78667J108 1,095 33,912 SH   DFND 2 33,912 0 0
Sage Therapeutics Inc COM 78667J108 1,262 39,069 SH   DFND 3 39,069 0 0
Sailpoint Technologies Holding COM 78781P105 23 363 SH   DFND 3 363 0 0
Salesforce.com COM 79466L302 50,695 307,167 SH   DFND 1 307,167 0 0
Salesforce.com COM 79466L302 345,928 2,096,027 SH   DFND 2 842,695 0 1,253,332
Salesforce.com COM 79466L302 52,012 315,150 SH   DFND 3 252,101 0 63,049
Salesforce.com COM 79466L302 105,381 638,516 SH   SOLE 0 277,869 0 360,647
Sana Biotechnology Inc COM 799566104 11,702 1,819,974 SH   DFND 1 1,819,974 0 0
Sana Biotechnology Inc COM 799566104 17,886 2,781,677 SH   DFND 2 2,781,677 0 0
Sana Biotechnology Inc COM 799566104 1,187 184,538 SH   DFND 3 184,538 0 0
Sana Biotechnology Inc COM 799566104 40,029 6,225,273 SH   SOLE 0 6,225,273 0 0
Sangamo Biosciences COM 800677106 10 2,510 SH   DFND 3 2,510 0 0
Sarepta Therapeutics Inc COM 803607100 15 199 SH   DFND 3 199 0 0
Schrodinger COM 80810D103 8,783 332,569 SH   DFND 1 332,569 0 0
Schrodinger COM 80810D103 11,097 420,169 SH   DFND 2 126,602 0 293,567
Schrodinger COM 80810D103 4,776 180,858 SH   DFND 3 180,858 0 0
Schrodinger COM 80810D103 8,473 320,840 SH   SOLE 0 320,840 0 0
Schweitzer-Maudit Int. COM 808541106 7 265 SH   DFND 3 265 0 0
Seagen Inc COM 81181C104 23 128 SH   DFND 3 128 0 0
Seer COM CL A 81578P106 2 223 SH   DFND 3 223 0 0
Sei Investments Co COM 784117103 22 409 SH   DFND 3 409 0 0
Service Corp.Intl. COM 817565104 160,402 2,320,636 SH   DFND 1 2,320,636 0 0
Service Corp.Intl. COM 817565104 535,501 7,747,414 SH   DFND 2 7,067,609 0 679,805
Service Corp.Intl. COM 817565104 97,795 1,414,852 SH   DFND 3 825,167 0 589,685
Service Corp.Intl. COM 817565104 442,732 6,405,261 SH   SOLE 0 4,196,879 0 2,208,382
Sherwin-Williams Co COM 824348106 9,953 44,453 SH   DFND 2 44,453 0 0
ShockWave Medical Inc COM 82489T104 23,396 122,381 SH   DFND 1 122,381 0 0
ShockWave Medical Inc COM 82489T104 38,616 201,997 SH   DFND 2 118,693 0 83,304
ShockWave Medical Inc COM 82489T104 29,166 152,568 SH   DFND 3 152,568 0 0
ShockWave Medical Inc COM 82489T104 16,420 85,892 SH   SOLE 0 85,892 0 0
Shopify 'A' CL A 82509L107 332,373 10,639,340 SH   DFND 1 10,639,340 0 0
Shopify 'A' CL A 82509L107 1,001,122 32,046,154 SH   DFND 2 22,699,524 0 9,346,630
Shopify 'A' CL A 82509L107 113,737 3,640,760 SH   DFND 3 2,805,300 0 835,460
Shopify 'A' CL A 82509L107 1 30 SH   DFND 4 30 0 0
Shopify 'A' CL A 82509L107 331,772 10,620,109 SH   SOLE 0 7,735,489 0 2,884,620
Shopify Inc COM 82509L107 3,025 97,020 SH   DFND 2 97,020 0 0
Shopify Inc COM 82509L107 59 1,890 SH   DFND 3 1,890 0 0
Signature Bank COM 82669G104 1,792 10,002 SH   SOLE 0 10,002 0 0
Silicon Motion Technology ADR COM 82706C108 33,649 402,015 SH   DFND 1 402,015 0 0
Silicon Motion Technology ADR COM 82706C108 292 3,484 SH   DFND 2 0 0 3,484
Silicon Motion Technology ADR COM 82706C108 4,714 56,318 SH   DFND 3 56,318 0 0
Silicon Motion Technology ADR COM 82706C108 18,634 222,630 SH   SOLE 0 222,630 0 0
Silk Road Medical COM 82710M100 9 235 SH   DFND 3 235 0 0
SiteOne Landscape Supply COM 82982L103 42,771 359,814 SH   DFND 1 359,814 0 0
SiteOne Landscape Supply COM 82982L103 133,049 1,119,285 SH   DFND 2 1,015,627 0 103,658
SiteOne Landscape Supply COM 82982L103 26,284 221,112 SH   DFND 3 130,617 0 90,495
SiteOne Landscape Supply COM 82982L103 118,269 994,947 SH   SOLE 0 646,665 0 348,282
Sixth Street Specialty Lending COM 83012A109 1,471 79,500 SH   DFND 1 79,500 0 0
Smartsheet COM 83200N103 10 311 SH   DFND 3 311 0 0
Snap Inc CL A 83304A106 53,349 4,063,120 SH   DFND 1 4,063,120 0 0
Snap Inc CL A 83304A106 77,977 5,938,837 SH   DFND 2 5,880,960 0 57,877
Snap Inc CL A 83304A106 3,276 249,520 SH   DFND 3 249,520 0 0
Snap Inc CL A 83304A106 14,403 1,096,937 SH   SOLE 0 1,096,937 0 0
Snap On COM 833034101 17 86 SH   DFND 3 86 0 0
Snowflake Inc COM 833445109 124,955 898,569 SH   DFND 1 898,569 0 0
Snowflake Inc COM 833445109 235,660 1,694,664 SH   DFND 2 1,628,651 0 66,013
Snowflake Inc COM 833445109 22,469 161,576 SH   DFND 3 111,323 0 50,253
Snowflake Inc COM 833445109 231,691 1,666,125 SH   SOLE 0 1,475,259 0 190,866
Solaredge Technologies Inc COM 83417M104 370 1,353 SH   DFND 1 1,353 0 0
Solaredge Technologies Inc COM 83417M104 46 167 SH   DFND 3 167 0 0
Sorrento Therapeutics COM 83587F202 9 4,314 SH   DFND 3 4,314 0 0
Spire Global Inc COM CL A 848560108 1,005 866,045 SH   SOLE 0 866,045 0 0
Splunk Inc COM 848637104 6,594 74,540 SH   DFND 1 74,540 0 0
Splunk Inc COM 848637104 11,884 134,348 SH   DFND 2 40,185 0 94,163
Splunk Inc COM 848637104 4,636 52,411 SH   DFND 3 52,411 0 0
Splunk Inc COM 848637104 6,536 73,884 SH   SOLE 0 73,884 0 0
Spotify Technology SA SHS L8681T102 109,832 1,170,538 SH   DFND 1 1,170,538 0 0
Spotify Technology SA SHS L8681T102 2,002,393 21,340,644 SH   DFND 2 16,485,102 0 4,855,542
Spotify Technology SA SHS L8681T102 52,394 558,391 SH   DFND 3 431,374 0 127,017
Spotify Technology SA SHS L8681T102 1 9 SH   DFND 4 9 0 0
Spotify Technology SA SHS L8681T102 293,693 3,130,055 SH   SOLE 0 2,517,383 0 612,672
Sprout Social COM 85209W109 18,645 321,078 SH   DFND 1 321,078 0 0
Sprout Social COM 85209W109 17,680 304,466 SH   DFND 2 91,127 0 213,339
Sprout Social COM 85209W109 8,151 140,364 SH   DFND 3 140,364 0 0
Sprout Social COM 85209W109 14,278 245,870 SH   SOLE 0 245,870 0 0
Staar Surgical COM PAR $0.01 852312305 102,397 1,443,638 SH   DFND 1 1,443,638 0 0
Staar Surgical COM PAR $0.01 852312305 128,252 1,808,153 SH   DFND 2 1,197,545 0 610,608
Staar Surgical COM PAR $0.01 852312305 40,479 570,693 SH   DFND 3 453,918 0 116,775
Staar Surgical COM PAR $0.01 852312305 103,762 1,462,874 SH   SOLE 0 1,140,401 0 322,473
Starbucks Corp COM 855244109 19,158 250,796 SH   DFND 1 250,796 0 0
Starbucks Corp COM 855244109 13,239 173,303 SH   DFND 2 171,160 0 2,143
Starbucks Corp COM 855244109 2,944 38,536 SH   DFND 3 38,536 0 0
Starbucks Corp COM 855244109 14,501 189,833 SH   SOLE 0 189,833 0 0
Stitch Fix COM CL A 860897107 6 1,147 SH   DFND 2 1,147 0 0
Stitch Fix COM CL A 860897107 160 32,301 SH   DFND 3 32,301 0 0
StoneCo COM CL A G85158106 1,235 160,397 SH   DFND 1 160,397 0 0
StoneCo COM CL A G85158106 9,537 1,238,614 SH   DFND 2 674,813 0 563,801
StoneCo COM CL A G85158106 70 9,131 SH   DFND 3 9,131 0 0
Stratasys SHS M85548101 4,241 226,300 SH   DFND 1 226,300 0 0
Stratasys SHS M85548101 6,485 346,075 SH   DFND 2 99,025 0 247,050
Stratasys SHS M85548101 2,876 153,480 SH   DFND 3 153,480 0 0
Stratasys SHS M85548101 2,710 144,600 SH   SOLE 0 144,600 0 0
Stryker COM 863667101 9 47 SH   DFND 3 47 0 0
Sumo Logic COM 86646P103 5 726 SH   DFND 3 726 0 0
Sunpower Corp COM 867652406 19 1,210 SH   DFND 3 1,210 0 0
Sutro Biopharma COM 869367102 5,431 1,042,428 SH   DFND 1 1,042,428 0 0
Sutro Biopharma COM 869367102 13 2,494 SH   DFND 2 2,494 0 0
Sutro Biopharma COM 869367102 362 69,532 SH   DFND 3 69,532 0 0
Sutro Biopharma COM 869367102 3,911 750,726 SH   SOLE 0 750,726 0 0
T. Rowe Price COM 74144T108 18,284 160,937 SH   DFND 1 160,937 0 0
T. Rowe Price COM 74144T108 172 1,513 SH   DFND 2 0 0 1,513
T. Rowe Price COM 74144T108 2,639 23,228 SH   DFND 3 23,228 0 0
T. Rowe Price COM 74144T108 10,234 90,076 SH   SOLE 0 90,076 0 0
TJX Companies COM 872540109 6,000 107,431 SH   DFND 2 107,431 0 0
TJX Companies COM 872540109 4,125 73,855 SH   SOLE 0 73,855 0 0
TSMC ADR SPONSORED ADR 874039100 574,425 7,026,601 SH   DFND 2 5,397,947 0 1,628,654
TSMC ADR SPONSORED ADR 874039100 1,150 14,066 SH   DFND 3 14,066 0 0
TSMC ADR SPONSORED ADR 874039100 4 52 SH   DFND 4 52 0 0
TSMC ADR SPONSORED ADR 874039100 73,705 901,587 SH   SOLE 0 729,513 0 172,074
Tabula Rasa HealthCare Inc COM 873379101 1,442 561,175 SH   DFND 1 561,175 0 0
Tabula Rasa HealthCare Inc COM 873379101 3 1,076 SH   DFND 2 1,076 0 0
Tabula Rasa HealthCare Inc COM 873379101 76 29,449 SH   DFND 3 29,449 0 0
Tabula Rasa HealthCare Inc COM 873379101 613 238,574 SH   SOLE 0 238,574 0 0
Tandem Diabetes Care COM NEW 875372203 8,683 146,692 SH   DFND 1 146,692 0 0
Tandem Diabetes Care COM NEW 875372203 23 382 SH   DFND 2 382 0 0
Tandem Diabetes Care COM NEW 875372203 638 10,772 SH   DFND 3 10,772 0 0
Tandem Diabetes Care COM NEW 875372203 8,782 148,377 SH   SOLE 0 148,377 0 0
Target Corp COM 87612E106 14 97 SH   DFND 3 97 0 0
Tata Motors Ltd ADR COM 876568502 59,161 2,286,839 SH   DFND 1 2,286,839 0 0
Tata Motors Ltd ADR COM 876568502 28,843 1,114,917 SH   DFND 2 1,114,917 0 0
Tata Motors Ltd ADR COM 876568502 918 35,474 SH   DFND 3 35,474 0 0
Tata Motors Ltd ADR COM 876568502 14,598 564,300 SH   SOLE 0 564,300 0 0
Teladoc COM 87918A105 92,845 2,795,681 SH   DFND 1 2,795,681 0 0
Teladoc COM 87918A105 92,272 2,778,440 SH   DFND 2 2,222,486 0 555,954
Teladoc COM 87918A105 44,947 1,353,416 SH   DFND 3 1,139,142 0 214,274
Teladoc COM 87918A105 26,969 812,086 SH   SOLE 0 666,063 0 146,023
Telus Corp COM 87971M103 9 397 SH   DFND 3 397 0 0
Tenable Holdings COM 88025T102 14 315 SH   DFND 3 315 0 0
Tencent ADR SPON ADR 88032Q109 3 66 SH   DFND 4 66 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 8,272 1,647,810 SH   DFND 1 1,647,810 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 147,550 29,392,337 SH   DFND 2 20,677,690 0 8,714,647
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 266 52,900 SH   DFND 3 52,900 0 0
Tencent Music Entertainment ADR SPONSORED ADS 88034P109 1 171 SH   DFND 4 171 0 0
Teradyne COM 880770102 70,113 782,948 SH   DFND 1 782,948 0 0
Teradyne COM 880770102 217,701 2,431,052 SH   DFND 2 2,209,838 0 221,214
Teradyne COM 880770102 42,702 476,851 SH   DFND 3 283,901 0 192,950
Teradyne COM 880770102 190,235 2,124,343 SH   SOLE 0 1,367,217 0 757,126
Tesla Inc COM 88160R101 774,822 1,150,577 SH   DFND 1 1,150,577 0 0
Tesla Inc COM 88160R101 3,507,578 5,208,604 SH   DFND 2 3,819,066 0 1,389,538
Tesla Inc COM 88160R101 380,581 565,147 SH   DFND 3 442,011 0 123,136
Tesla Inc COM 88160R101 1,670,065 2,479,976 SH   SOLE 0 2,001,285 0 478,691
Texas Instruments COM 882508104 3,697 24,059 SH   SOLE 0 24,059 0 0
Texas Roadhouse Inc COM 882681109 10 131 SH   DFND 3 131 0 0
The Trade Desk COM CL A 88339J105 439,283 10,486,594 SH   DFND 1 10,486,594 0 0
The Trade Desk COM CL A 88339J105 1,053,621 25,152,095 SH   DFND 2 18,189,648 0 6,962,447
The Trade Desk COM CL A 88339J105 123,716 2,953,345 SH   DFND 3 2,264,122 0 689,223
The Trade Desk COM CL A 88339J105 355,090 8,476,715 SH   SOLE 0 5,392,641 0 3,084,074
Thermo Fisher Scientific COM 883556102 95,820 176,373 SH   DFND 1 176,373 0 0
Thermo Fisher Scientific COM 883556102 316,584 582,728 SH   DFND 2 533,783 0 48,945
Thermo Fisher Scientific COM 883556102 57,514 105,864 SH   DFND 3 62,042 0 43,822
Thermo Fisher Scientific COM 883556102 272,297 501,210 SH   SOLE 0 334,590 0 166,620
Thor Industries Inc COM 885160101 11 151 SH   DFND 3 151 0 0
Toro Co COM 891092108 19 245 SH   DFND 3 245 0 0
Tractor Supply Co COM 892356106 30 155 SH   DFND 3 155 0 0
TransMedics Group COM 89377M109 36 1,155 SH   DFND 2 1,155 0 0
TransMedics Group COM 89377M109 1,024 32,572 SH   DFND 3 32,572 0 0
Trip.com Group Sponsored ADR AMERICAN DEP SHS 89677Q107 21,927 798,804 SH   DFND 2 384,885 0 413,919
Trupanion COM 898202106 11,907 197,600 SH   DFND 1 197,600 0 0
Trupanion COM 898202106 20,084 333,282 SH   DFND 2 99,161 0 234,121
Trupanion COM 898202106 8,700 144,372 SH   DFND 3 144,372 0 0
Trupanion COM 898202106 22,967 381,138 SH   SOLE 0 381,138 0 0
TuSimple Hdgs CL A 90089L108 3 349 SH   DFND 3 349 0 0
Twilio Inc CL A 90138F102 135,490 1,616,627 SH   DFND 1 1,616,627 0 0
Twilio Inc CL A 90138F102 242,789 2,896,894 SH   DFND 2 2,760,838 0 136,056
Twilio Inc CL A 90138F102 26,580 317,143 SH   DFND 3 221,726 0 95,417
Twilio Inc CL A 90138F102 100,415 1,198,121 SH   SOLE 0 877,530 0 320,591
Ultragenyx COM 90400D108 7 115 SH   DFND 3 115 0 0
United Parcel Service CL B 911312106 75,117 411,511 SH   DFND 1 411,511 0 0
United Parcel Service CL B 911312106 740 4,052 SH   DFND 2 0 0 4,052
United Parcel Service CL B 911312106 10,588 58,006 SH   DFND 3 58,006 0 0
United Parcel Service CL B 911312106 46,966 257,293 SH   SOLE 0 257,293 0 0
UnitedHealth COM 91324P102 34 67 SH   DFND 3 67 0 0
Unity Biotechnology Inc COM 91381U101 140 248,000 SH   DFND 1 248,000 0 0
Unity Biotechnology Inc COM 91381U101 192 341,111 SH   SOLE 0 341,111 0 0
Upwork Inc COM 91688F104 53,401 2,582,263 SH   DFND 1 2,582,263 0 0
Upwork Inc COM 91688F104 40,816 1,973,704 SH   DFND 2 622,315 0 1,351,389
Upwork Inc COM 91688F104 20,537 993,097 SH   DFND 3 909,038 0 84,059
Upwork Inc COM 91688F104 27,751 1,341,907 SH   SOLE 0 1,341,907 0 0
Vale SA ADR ADR 91912E105 11,659 796,951 SH   DFND 1 796,951 0 0
Vale SA ADR ADR 91912E105 70,921 4,847,672 SH   DFND 2 3,553,414 0 1,294,258
Vale SA ADR ADR 91912E105 616 42,102 SH   DFND 3 42,102 0 0
Varonis Systems Inc COM 922280102 22 735 SH   DFND 2 735 0 0
Varonis Systems Inc COM 922280102 614 20,943 SH   DFND 3 20,943 0 0
Veeco Instruments COM 922417100 4,504 232,154 SH   DFND 1 232,154 0 0
Veeco Instruments COM 922417100 9,676 498,785 SH   DFND 2 153,205 0 345,580
Veeco Instruments COM 922417100 4,443 229,031 SH   DFND 3 229,031 0 0
Veeva Systems Inc Class A COM 922475108 1,370 6,920 SH   DFND 1 6,920 0 0
Veeva Systems Inc Class A COM 922475108 3,027 15,287 SH   DFND 2 15,287 0 0
Veeva Systems Inc Class A COM 922475108 3,545 17,899 SH   DFND 3 17,899 0 0
Verint Systems Inc COM 92343X100 17 395 SH   DFND 3 395 0 0
Veritone COM 92347M100 4 649 SH   DFND 3 649 0 0
ViewRay COM 92672L107 2 911 SH   DFND 3 911 0 0
Vimeo Inc. COM 92719V100 1,026 170,422 SH   DFND 1 170,422 0 0
Vimeo Inc. COM 92719V100 3,032 503,582 SH   DFND 2 454,776 0 48,806
Vimeo Inc. COM 92719V100 623 103,417 SH   DFND 3 60,413 0 43,004
Vimeo Inc. COM 92719V100 2,696 447,822 SH   SOLE 0 284,465 0 163,357
Vir Biotechnology Inc COM 92764N102 755 29,649 SH   DFND 1 29,649 0 0
Vir Biotechnology Inc COM 92764N102 1,614 63,371 SH   DFND 2 63,371 0 0
Vir Biotechnology Inc COM 92764N102 1,960 76,947 SH   DFND 3 76,947 0 0
Vir Biotechnology Inc COM 92764N102 95,790 3,760,885 SH   SOLE 0 3,760,885 0 0
Visa Inc-Class A Shares COM CL A 92826C839 10,315 52,389 SH   DFND 2 52,389 0 0
Visa Inc-Class A Shares COM CL A 92826C839 22 110 SH   DFND 3 110 0 0
Visteon Corp COM 92839U206 24 230 SH   DFND 3 230 0 0
Vuzix COM 92921W300 7 924 SH   DFND 3 924 0 0
WD-40 Co COM 929236107 12 58 SH   DFND 3 58 0 0
WEC Energy Group COM 92939U106 1,912 18,996 SH   DFND 1 18,996 0 0
Wal-Mart Stores COM 931142103 12 101 SH   DFND 3 101 0 0
Warby Parker Inc CL A COM 93403J106 1,927 171,156 SH   DFND 1 171,156 0 0
Warby Parker Inc CL A COM 93403J106 6,179 548,795 SH   DFND 2 215,689 0 333,106
Warby Parker Inc CL A COM 93403J106 913 81,120 SH   DFND 3 57,451 0 23,669
Warby Parker Inc CL A COM 93403J106 61,661 5,476,151 SH   SOLE 0 5,476,151 0 0
Waters COM 941848103 8,901 26,893 SH   DFND 1 26,893 0 0
Waters COM 941848103 11,613 35,086 SH   DFND 2 27,419 0 7,667
Waters COM 941848103 4,151 12,542 SH   DFND 3 8,933 0 3,609
Waters COM 941848103 519 1,567 SH   SOLE 0 1,567 0 0
Watsco Inc COM 942622200 205,881 862,075 SH   DFND 1 862,075 0 0
Watsco Inc COM 942622200 226,884 950,020 SH   DFND 2 926,607 0 23,413
Watsco Inc COM 942622200 21,457 89,847 SH   DFND 3 83,789 0 6,058
Watsco Inc COM 942622200 64,474 269,971 SH   SOLE 0 269,971 0 0
Wayfair Inc Class A CL A 94419L101 116,139 2,666,186 SH   SOLE 0 2,385,331 0 280,855
Wayfair Inc Class A CL A 94419L101 16,422 377,008 SH   DFND 3 292,277 0 84,731
Wayfair Inc Class A CL A 94419L101 99,823 2,291,632 SH   DFND 1 2,291,632 0 0
Wayfair Inc Class A CL A 94419L101 161,491 3,707,319 SH   DFND 2 3,489,631 0 217,688
West Pharmaceutical Services COM 955306105 12 40 SH   DFND 3 40 0 0
Wheaton Precious Metals COM 962879102 736 20,416 SH   DFND 1 20,416 0 0
Williams-Sonoma Inc COM 969904101 7 63 SH   DFND 3 63 0 0
Wix Com SHS M98068105 530,399 8,091,511 SH   DFND 2 6,099,522 0 1,991,989
Wix Com SHS M98068105 27 406 SH   DFND 3 406 0 0
Workday Inc CL A 98138H101 163,183 1,169,101 SH   SOLE 0 616,286 0 552,815
Workday Inc CL A 98138H101 78,878 565,109 SH   DFND 3 456,435 0 108,674
Workday Inc CL A 98138H101 187,632 1,344,264 SH   DFND 1 1,344,264 0 0
Workday Inc CL A 98138H101 598,069 4,284,773 SH   DFND 2 2,332,750 0 1,952,023
XP CL A G98239109 160 8,893 SH   DFND 4 8,893 0 0
XP CL A G98239109 1,228 68,387 SH   DFND 1 68,387 0 0
XP CL A G98239109 3,087 171,904 SH   DFND 2 12,129 0 159,775
XP CL A G98239109 3,749 208,760 SH   DFND 3 22,286 0 186,474
XPEL COM 98379L100 15 326 SH   DFND 3 326 0 0
Xencor Inc COM 98401F105 29 1,054 SH   DFND 2 1,054 0 0
Xencor Inc COM 98401F105 810 29,603 SH   DFND 3 29,603 0 0
Xperi Holding Corp COM 98390M103 21 1,448 SH   DFND 3 1,448 0 0
Xylem COM 98419M100 84,050 1,075,082 SH   DFND 3 839,720 0 235,362
Xylem COM 98419M100 19,571 250,337 SH   SOLE 0 92,673 0 157,664
Xylem COM 98419M100 82,101 1,050,152 SH   DFND 1 1,050,152 0 0
Xylem COM 98419M100 42,591 544,783 SH   DFND 2 290,273 0 254,510
Zai Lab ADR ADR 98887Q104 19,604 567,403 SH   DFND 2 18,840 0 548,563
Zai Lab ADR ADR 98887Q104 5,865 169,749 SH   DFND 3 13,963 0 155,786
Ziff Davis Inc COM 48123V102 4 53 SH   DFND 3 53 0 0
Zillow Group Inc Class A CL A 98954M101 1,996 62,733 SH   DFND 3 62,733 0 0
Zillow Group Inc Class A CL A 98954M101 5,087 159,914 SH   DFND 2 48,317 0 111,597
Zillow Group Inc Class A CL A 98954M101 986 30,990 SH   DFND 1 30,990 0 0
Zillow Group Inc Class A CL A 98954M101 2,890 90,840 SH   SOLE 0 90,840 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 18,528 583,573 SH   SOLE 0 583,573 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 8,407 264,788 SH   DFND 3 264,788 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 30,977 975,649 SH   DFND 1 975,649 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 22,023 693,637 SH   DFND 2 205,555 0 488,082
Zoom Video Communications Inc CL A 98980L101 210,032 1,945,280 SH   SOLE 0 1,567,770 0 377,510
Zoom Video Communications Inc CL A 98980L101 45,459 421,038 SH   DFND 3 347,731 0 73,307
Zoom Video Communications Inc CL A 98980L101 404,298 3,744,539 SH   DFND 2 2,407,476 0 1,337,063
Zoom Video Communications Inc CL A 98980L101 153,992 1,426,245 SH   DFND 1 1,426,245 0 0
Zuora Inc Class A COM CL A 98983V106 6,994 781,436 SH   SOLE 0 781,436 0 0
Zuora Inc Class A COM CL A 98983V106 17,992 2,010,224 SH   DFND 1 2,010,224 0 0
Zuora Inc Class A COM CL A 98983V106 11,537 1,289,086 SH   DFND 2 388,108 0 900,978
Zuora Inc Class A COM CL A 98983V106 5,431 606,825 SH   DFND 3 606,825 0 0
Zymergen Inc COM 98985X100 3,471 2,821,956 SH   SOLE 0 2,821,956 0 0
Zynex COM 98986M103 4 481 SH   DFND 3 481 0 0
dLocal CL A G29018101 6,465 246,272 SH   DFND 3 0 0 246,272
dLocal CL A G29018101 14,535 553,728 SH   DFND 1 553,728 0 0
dLocal CL A G29018101 4 142 SH   DFND 2 142 0 0
iRobot COM 462726100 7,860 213,872 SH   DFND 1 213,872 0 0
iRobot COM 462726100 8,857 241,019 SH   DFND 2 76,770 0 164,249
iRobot COM 462726100 4,898 133,267 SH   SOLE 0 133,267 0 0
iRobot COM 462726100 4,822 131,214 SH   DFND 3 120,426 0 10,788
nLIGHT COM 65487K100 5 468 SH   DFND 3 468 0 0