The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100 106,206 3,937,914 SH   SOLE   3,937,914 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 134,114 2,102,758 SH   SOLE   2,102,758 0 0
ACTIVISION BLIZZARD INC COM 00507V109 61,622 796,247 SH   SOLE   796,247 0 0
ADAPTHEALTH CORP COMMON STOCK 00653Q102 94,884 4,074,029 SH   SOLE   4,074,029 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 1,019,486 29,993,708 SH   SOLE   29,993,708 0 0
ALIGN TECHNOLOGY INC COM 016255101 74,242 111,570 SH   SOLE   111,570 0 0
AMAZON COM INC COM 023135106 666,561 202,908 SH   SOLE   202,908 0 0
AMERIPRISE FINL INC COM 03076C106 369,997 1,400,867 SH   SOLE   1,400,867 0 0
API GROUP CORP COM STK 00187Y100 678,333 33,333,333 SH   SOLE   33,333,333 0 0
ASSURANT INC COM 04621X108 286,763 1,817,833 SH   SOLE   1,817,833 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 58,027 1,655,087 SH   SOLE   1,655,087 0 0
AVANTOR INC COM 05352A100 291,257 7,121,192 SH   SOLE   7,121,192 0 0
BILIBILI INC SPONS ADS REP Z 090040106 36,259 547,961 SH   SOLE   547,961 0 0
BOOKING HOLDINGS INC COM 09857L108 319,055 134,403 SH   SOLE   134,403 0 0
BOSTON SCIENTIFIC CORP COM 101137107 297,933 6,866,405 SH   SOLE   6,866,405 0 0
BRIDGEBIO PHARMA INC COM 10806X102 1,247,726 26,620,991 SH   SOLE   26,620,991 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 415,567 7,023,264 SH   SOLE   7,023,264 0 0
BROOKFIELD ASSET MGMT INC CL A LTD VT SH 112585104 908,980 16,987,106 SH   SOLE   16,987,106 0 0
CANADIAN PAC RY LTD COM 13645T100 224,337 3,447,633 SH   SOLE   3,447,633 0 0
CATALENT INC COM 148806102 154,765 1,163,034 SH   SOLE   1,163,034 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 41,156 762,296 SH   SOLE   762,296 0 0
CENTENE CORP DEL COM 15135B101 615,879 9,884,106 SH   SOLE   9,884,106 0 0
CHARLES RIV LABS INTL INC COM 159864107 73,209 177,403 SH   SOLE   177,403 0 0
CHUBB LIMITED COM H1467J104 527,370 3,039,945 SH   SOLE   3,039,945 0 0
COMCAST CORP NEW CL A 20030N101 569,179 10,176,623 SH   SOLE   10,176,623 0 0
COUPA SOFTWARE INC COM 22266L106 858,724 3,917,895 SH   SOLE   3,917,895 0 0
COUPA SOFTWARE INC NOTE 0.375% 6/1 22266LAF3 108,438 100,000,000 PRN   SOLE   100,000,000 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109 28,746 1,211,396 SH   SOLE   1,211,396 0 0
DEERE & CO COM 244199105 240,724 718,430 SH   SOLE   718,430 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 45,272 2,727,249 SH   SOLE   2,727,249 0 0
FACEBOOK INC CL A 30303M102 578,899 1,705,703 SH   SOLE   1,705,703 0 0
FARFETCH LTD ORD SH CL A 30744W107 432,446 11,538,035 SH   SOLE   11,538,035 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 872,697 7,172,066 SH   SOLE   7,172,066 0 0
FIGS INC CL A 30260D103 547,543 14,742,689 SH   SOLE   14,742,689 0 0
FLEETCOR TECHNOLOGIES INC COM 339041105 644,974 2,468,612 SH   SOLE   2,468,612 0 0
FORTIVE CORP COM 34959J108 762,740 10,808,273 SH   SOLE   10,808,273 0 0
GENERAL ELECTRIC CO COM NEW 369604301 1,743,649 16,923,702 SH   SOLE   16,923,702 0 0
GINKGO BIOWORKS HOLDINGS INC CL A SHS 37611X100 3,929,649 339,055,144 SH   SOLE   339,055,144 0 0
GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 18,834 1,357,859 SH   SOLE   1,357,859 0 0
GUARDANT HEALTH INC COM 40131M109 611,916 4,894,936 SH   SOLE   4,894,936 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 122,728 1,679,130 SH   SOLE   1,679,130 0 0
HUMANA INC COM 444859102 1,170,226 3,007,133 SH   SOLE   3,007,133 0 0
ICICI BANK LIMITED ADR 45104G104 325,373 17,242,857 SH   SOLE   17,242,857 0 0
ICOSAVAX INC COM 45114M109 54,824 1,852,789 SH   SOLE   1,852,789 0 0
ILLUMINA INC COM 452327109 62,999 155,319 SH   SOLE   155,319 0 0
INGERSOLL RAND INC COM 45687V106 183,543 3,641,009 SH   SOLE   3,641,009 0 0
INHIBRX INC COM 45720L107 176,738 5,305,866 SH   SOLE   5,305,866 0 0
INSULET CORP COM 45784P101 287,965 1,013,141 SH   SOLE   1,013,141 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 171,649 1,279,531 SH   SOLE   1,279,531 0 0
JD.COM INC SPON ADR CL A 47215P106 527,116 7,296,733 SH   SOLE   7,296,733 0 0
KARUNA THERAPEUTICS INC COM 48576A100 106,268 868,696 SH   SOLE   868,696 0 0
KINNATE BIOPHARMA INC COM 49705R105 41,907 1,820,462 SH   SOLE   1,820,462 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 222,829 791,746 SH   SOLE   791,746 0 0
LITHIA MTRS INC COM 536797103 254,733 803,472 SH   SOLE   803,472 0 0
MARSH & MCLENNAN COS INC COM 571748102 175,081 1,156,185 SH   SOLE   1,156,185 0 0
MATCH GROUP INC NEW COM 57667L107 214,292 1,365,007 SH   SOLE   1,365,007 0 0
MCDONALDS CORP COM 580135101 720,994 2,990,312 SH   SOLE   2,990,312 0 0
MELI KASZEK PIONEER CORP CLASS A ORD G5S74L106 11,050 1,000,000 SH   SOLE   1,000,000 0 0
METLIFE INC COM 59156R108 59,208 959,147 SH   SOLE   959,147 0 0
MICROSOFT CORP COM 594918104 1,026,625 3,641,547 SH   SOLE   3,641,547 0 0
MOLINA HEALTHCARE INC COM 60855R100 253,736 935,226 SH   SOLE   935,226 0 0
NETFLIX INC COM 64110L106 250,797 410,913 SH   SOLE   410,913 0 0
NUVALENT INC COM 670703107 37,155 1,647,671 SH   SOLE   1,647,671 0 0
OLAPLEX HLDGS INC COM 679369108 74,048 3,022,372 SH   SOLE   3,022,372 0 0
ON HLDG AG NAMEN AKT A H5919C104 9,039 300,000 SH   SOLE   300,000 0 0
ORION ACQUISITION CORP UNIT 02/19/2026 68626A207 36,277 3,671,788 SH   SOLE   3,671,788 0 0
PALO ALTO NETWORKS INC COM 697435105 610,053 1,273,598 SH   SOLE   1,273,598 0 0
PARKER-HANNIFIN CORP COM 701094104 867,173 3,101,255 SH   SOLE   3,101,255 0 0
PELOTON INTERACTIVE INC CL A COM 70614W100 564,529 6,485,107 SH   SOLE   6,485,107 0 0
PHARVARIS N V COM N69605108 41,254 2,391,517 SH   SOLE   2,391,517 0 0
PINTEREST INC CL A 72352L106 368,411 7,230,842 SH   SOLE   7,230,842 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 53,350 1,790,284 SH   SOLE   1,790,284 0 0
PROCEPT BIOROBOTICS CORP COM 74276L105 187,236 4,907,892 SH   SOLE   4,907,892 0 0
PVH CORPORATION COM 693656100 119,411 1,161,695 SH   SOLE   1,161,695 0 0
RALLYBIO CORP COM 75120L100 73,744 4,194,777 SH   SOLE   4,194,777 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 149,638 4,140,508 SH   SOLE   4,140,508 0 0
SEMA4 HOLDINGS CORP COM CL A 81663L101 22,770 3,000,000 SH   SOLE   3,000,000 0 0
SERVICENOW INC COM 81762P102 348,095 559,395 SH   SOLE   559,395 0 0
SMART SH GLOBAL LTD ADS 83193E102 1,570 470,000 SH   SOLE   470,000 0 0
SNOWFLAKE INC CL A 833445109 434,391 1,436,335 SH   SOLE   1,436,335 0 0
SUNRUN INC COM 86771W105 387,208 8,800,183 SH   SOLE   8,800,183 0 0
T-MOBILE US INC COM 872590104 1,306,370 10,225,185 SH   SOLE   10,225,185 0 0
TALARIS THERAPEUTICS INC COM 87410C104 44,607 3,289,617 SH   SOLE   3,289,617 0 0
TENET HEALTHCARE CORP COM NEW 88033G407 222,830 3,353,856 SH   SOLE   3,353,856 0 0
TESLA INC COM 88160R101 297,634 383,806 SH   SOLE   383,806 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 104,117 182,237 SH   SOLE   182,237 0 0
UBER TECHNOLOGIES INC COM 90353T100 286,355 6,391,844 SH   SOLE   6,391,844 0 0
UNITEDHEALTH GROUP INC COM 91324P102 283,862 726,474 SH   SOLE   726,474 0 0
VISA INC COM CL A 92826C839 587,333 2,636,735 SH   SOLE   2,636,735 0 0
VTEX SHS CL A G9470A102 62,551 3,040,896 SH   SOLE   3,040,896 0 0
WILLIS TOWERS WATSON PLC LTD SHS G96629103 269,618 1,159,849 SH   SOLE   1,159,849 0 0
ZAI LAB LTD ADR 98887Q104 309,052 2,932,456 SH   SOLE   2,932,456 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 141,162 2,118,284 SH   SOLE   2,118,284 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 498,952 3,409,073 SH   SOLE   3,409,073 0 0
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 308,306 1,178,992 SH   SOLE   1,178,992 0 0
ZOOMINFO TECHNOLOGIES INC COM CL A 98980F104 236,142 3,859,159 SH   SOLE   3,859,159 0 0