The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100 7,042 59,498 SH   SOLE   59,498 0 0
ABBVIE INC COM 00287Y109 9,775 60,300 SH   SOLE   60,300 0 0
AEROVATE THERAPEUTICS INC COM 008064107 4,013 218,913 SH   SOLE   17,308 0 201,605
AGILENT TECHNOLOGIES INC COM 00846U101 503 3,800 SH   SOLE   3,800 0 0
AGILITI INC COM 00848J104 10,121 479,647 SH   SOLE   106,945 0 372,702
ALIGN TECHNOLOGY INC COM 016255101 1,053 2,415 SH   SOLE   2,415 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 665 4,070 SH   SOLE   4,070 0 0
AMGEN INC COM 031162100 2,696 11,150 SH   SOLE   11,150 0 0
AMICUS THERAPEUTICS INC COM 03152W109 5,907 623,782 SH   SOLE   41,525 0 582,257
ANTHEM INC COM 036752103 3,389 6,900 SH   SOLE   6,900 0 0
APELLIS PHARMACEUTICALS, INC COM 03753U106 3,531 69,500 SH   SOLE   3,500 0 66,000
ARCUS BIOSCIENCES INC COM 03969F109 10,682 338,480 SH   SOLE   79,809 0 258,671
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 4,221 219,136 SH   SOLE   17,980 0 201,156
ARROWHEAD PHARMACEUTICALS INC COM 04280A100 5,505 119,700 SH   SOLE   6,300 0 113,400
ARVINAS INC COM 04335A105 11,181 166,131 SH   SOLE   26,756 0 139,375
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 719 6,129 SH   SOLE   6,129 0 0
ATRICURE INC COM 04963C209 14,327 218,164 SH   SOLE   32,812 0 185,352
AXONICS COM 05465P101 3,099 49,500 SH   SOLE   0 0 49,500
BEIGENE LTD SPONSORED ADR 07725L102 864 4,580 SH   SOLE   4,580 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 5,440 790,637 SH   SOLE   298,027 0 492,610
BETTER THERAPEUTICS INC COMMON STOCK 08773T104 1,739 878,531 SH   SOLE   383,742 0 494,789
BIOMARIN PHARMACEUTICAL INC COM 09061G101 8,106 105,130 SH   SOLE   11,130 0 94,000
BIOGEN INC COM 09062X103 3,623 17,202 SH   SOLE   17,202 0 0
BIONTECH SE SPONSORED ADS 09075V102 447 2,620 SH   SOLE   2,620 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 5,232 81,900 SH   SOLE   3,800 0 78,100
BOSTON SCIENTIFIC CORP COM 101137107 4,550 102,726 SH   SOLE   102,726 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 2,045 28,000 SH   SOLE   28,000 0 0
CIGNA CORP COM 125523100 2,552 10,650 SH   SOLE   10,650 0 0
CENTENE CORP DEL COM 15135B101 3,283 39,000 SH   SOLE   39,000 0 0
CERTARA INC COM 15687V109 5,490 255,584 SH   SOLE   18,455 0 237,129
CHECKMATE PHARMACEUTICALS INC COM 162818108 1,728 541,765 SH   SOLE   541,765 0 0
CONVEY HEALTH SOLUTIONS HLDG COM 21258C108 3,059 467,793 SH   SOLE   0 0 467,793
CYTOKINETICS INC COM 23282W605 2,577 70,000 SH   SOLE   0 0 70,000
DANAHER CORPORATION COM 235851102 4,422 15,075 SH   SOLE   15,075 0 0
DENALI THERAPEUTICS INC COM 24823R105 6,662 207,100 SH   SOLE   14,250 0 192,850
DEXCOM INC COM 252131107 3,581 7,000 SH   SOLE   7,000 0 0
DR REDDYS LABS LTD ADR 256135203 279 5,004 SH   SOLE   5,004 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 1,866 15,850 SH   SOLE   15,850 0 0
EFFECTOR THERAPEUTCS INC COM 28202V108 9,555 2,382,744 SH   SOLE   2,382,744 0 0
EVOLENT HEALTH INC CL A 30050B101 12,666 392,142 SH   SOLE   0 0 392,142
EXELIXIS INC COM 30161Q104 8,248 363,840 SH   SOLE   28,840 0 335,000
EXSCIENTIA PLC ADS 30223G102 3,394 235,683 SH   SOLE   60,601 0 175,082
FATE THERAPEUTICS INC COM 31189P102 7,489 193,160 SH   SOLE   10,160 0 183,000
FUSION PHARMACEUTICALS INC COM 36118A100 297 38,198 SH   SOLE   38,198 0 0
GILEAD SCIENCES INC COM 375558103 1,486 25,000 SH   SOLE   25,000 0 0
GUARDANT HEALTH INC COM 40131M109 316 4,770 SH   SOLE   4,770 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 5,025 126,000 SH   SOLE   0 0 126,000
HEALTH CATALYST INC COM 42225T107 6,578 251,739 SH   SOLE   0 0 251,739
HEALTHEQUITY INC COM 42226A107 16,186 240,000 SH   SOLE   72,500 0 167,500
HUMANA INC COM 444859102 5,015 11,525 SH   SOLE   11,525 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 4,535 28,800 SH   SOLE   0 0 28,800
ILLUMINA INC COM 452327109 685 1,960 SH   SOLE   1,960 0 0
IMMUNOGEN INC COM 45253H101 4,183 878,844 SH   SOLE   65,238 0 813,606
INARI MED INC COM 45332Y109 14,598 161,060 SH   SOLE   29,570 0 131,490
INCYTE CORPORATION COM 45337C102 465 5,860 SH   SOLE   5,860 0 0
INSMED INC COM 457669307 12,416 528,342 SH   SOLE   23,871 0 504,471
INSPIRE MED SYS INC COM 457730109 13,258 51,650 SH   SOLE   0 0 51,650
INTELLIA THERAPEUTICS INC COM 45826J105 5,247 72,200 SH   SOLE   3,300 0 68,900
IOVANCE BIOTHERAPEUTICS INC COM 462260100 3,696 222,000 SH   SOLE   20,000 0 202,000
ITEOS THERAPEUTICS INC COM 46565G104 7,535 234,150 SH   SOLE   76,250 0 157,900
JASPER THERAPEUTICS INC COM 471871103 2,396 675,000 SH   SOLE   75,000 0 600,000
JOHNSON & JOHNSON COM 478160104 12,893 72,750 SH   SOLE   72,750 0 0
LEGEND BIOTECH CORP SPON ADS 52490G102 436 12,000 SH   SOLE   12,000 0 0
LILLY ELI & CO COM 532457108 8,152 28,465 SH   SOLE   28,465 0 0
MARAVAI LIFESCIENCES HLDGS I COM 56600D107 2,998 85,000 SH   SOLE   0 0 85,000
MERCK & CO INC COM 58933Y105 4,738 57,750 SH   SOLE   57,750 0 0
MIRATI THERAPEUTICS INC COM 60468T105 4,920 59,837 SH   SOLE   20,590 0 39,247
MODERNA INC COM 60770K107 2,964 17,205 SH   SOLE   17,205 0 0
MOLINA HEALTHCARE INC COM 60855R100 2,719 8,150 SH   SOLE   8,150 0 0
908 DEVICES INC COM 65443P102 2,564 134,872 SH   SOLE   12,415 0 122,457
NOVAVAX INC COM 670002401 3,719 50,500 SH   SOLE   4,300 0 46,200
OUTSET MED INC COM 690145107 5,051 111,250 SH   SOLE   36,750 0 74,500
PTC THERAPEUTICS INC COM 69366J200 9,864 264,391 SH   SOLE   12,100 0 252,291
PFIZER INC COM 717081103 9,572 184,900 SH   SOLE   184,900 0 0
PRIVIA HEALTH GROUP INC COM 74276R102 9,664 361,550 SH   SOLE   83,638 0 277,912
R1 RCM INC COM 749397105 14,142 528,494 SH   SOLE   94,194 0 434,300
RALLYBIO CORP COM 75120L100 2,688 385,069 SH   SOLE   0 0 385,069
REGENERON PHARMCTCLS COM 75886F107 2,123 3,040 SH   SOLE   3,040 0 0
REPARE THERAPEUTICS COM 760273102 3,386 237,785 SH   SOLE   20,550 0 217,235
ROCKET PHARMACEUTICALS COM 77313F106 4,821 303,975 SH   SOLE   21,185 0 282,790
SEAGEN INC COM 81181C104 5,925 41,130 SH   SOLE   41,130 0 0
SHOCKWAVE MEDICAL INC COM 82489T104 7,258 35,000 SH   SOLE   0 0 35,000
SIGHT SCIENCES INC COM 82657M105 1,965 170,000 SH   SOLE   0 0 170,000
SILK ROAD MEDICAL INC COM 82710M100 8,630 209,000 SH   SOLE   0 0 209,000
SONENDO INC COM 835431107 437 108,869 SH   SOLE   0 0 108,869
STAAR SURGICAL CO COM 852312305 4,994 62,500 SH   SOLE   0 0 62,500
STRYKER CORPORATION COM 863667101 1,858 6,950 SH   SOLE   6,950 0 0
SYNEOS HEALTH INC CL A 87166B102 14,272 176,306 SH   SOLE   49,606 0 126,700
TALARIS THERAPEUTICS INC COM 87410C104 2,250 228,624 SH   SOLE   0 0 228,624
TANDEM DIABETES CARE INC COM 875372203 9,255 79,588 SH   SOLE   13,325 0 66,263
TENET HEALTHCARE CORP COM 88033G407 12,292 143,000 SH   SOLE   0 0 143,000
THERMO FISHER SCIENTIFIC INC COM 883556102 9,879 16,725 SH   SOLE   16,725 0 0
TREACE MED CONCEPTS INC COM 89455T109 3,990 211,024 SH   SOLE   0 0 211,024
TURNING POINT THERAPEUTICS INC COM 90041T108 7,541 280,850 SH   SOLE   12,100 0 268,750
UNITEDHEALTH GROUP INC COM 91324P102 16,676 32,700 SH   SOLE   32,700 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 1,900 7,281 SH   SOLE   7,281 0 0
ZAI LAB LTD ADR 98887Q104 528 12,000 SH   SOLE   12,000 0 0
BIOHAVEN PHARMACEUTICAL HOLDING CO COM G11196105 12,551 105,850 SH   SOLE   18,850 0 87,000
HORIZON THERAPEUTICS PUB L SHS G46188101 5,205 49,475 SH   SOLE   49,475 0 0
ICON PLC SHS G4705A100 535 2,200 SH   SOLE   2,200 0 0
MEDTRONIC PLC SHS G5960L103 2,502 22,551 SH   SOLE   22,551 0 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107 12,415 665,347 SH   SOLE   0 0 665,347
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 205 3,270 SH   SOLE   3,270 0 0
PROCAPS GROUP SA SHS L7756P102 929 109,245 SH   SOLE   109,245 0 0
AFFIMED N V COM N01045108 295 67,500 SH   SOLE   67,500 0 0
STEVANATO GROUP SPA ORD SHS T9224W109 395 19,643 SH   SOLE   19,643 0 0