The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1 800 FLOWERS COM INC CL A 68243Q106 1,255 53,700 SH   DFND 0 0 53,700 0
10X GENOMICS INC CL A COM 88025U109 25,541 171,462 SH   DFND 0 0 171,462 0
2SEVENTY BIO INC COMMON STOCK 901384107 15,037 586,707 SH   DFND 0 0 586,707 0
ABB LTD SPONSORED ADR 000375204 31,070 813,993 SH   DFND 0 0 813,993 0
ABEONA THERAPEUTICS INC COM 00289Y107 1,078 3,200,000 SH   DFND 0 0 3,200,000 0
ACADEMY SPORTS & OUTDOORS IN COM 00402L107 17,887 407,455 SH   DFND 0 0 407,455 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 11,067 182,317 SH   DFND 0 0 182,317 0
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102 5,010 1,000,000 SH   DFND 0 0 1,000,000 0
ACLARIS THERAPEUTICS INC COM 00461U105 9,348 642,900 SH   DFND 0 0 642,900 0
ACORDA THERAPEUTICS INC COM NEW 00484M601 1,110 464,276 SH   DFND 0 0 464,276 0
ACTIVISION BLIZZARD INC COM 00507V109 47,217 709,708 SH   DFND 0 0 709,708 0
ACTIVISION BLIZZARD INC COM 00507V109 26,612 400,000 SH Call DFND 0 0 400,000 0
ACV AUCTIONS INC COM CL A 00091G104 9,632 511,247 SH   DFND 0 0 511,247 0
ADAPTHEALTH CORP COMMON STOCK 00653Q102 25,940 1,060,500 SH   DFND 0 0 1,060,500 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 2,120 565,208 SH   DFND 0 0 565,208 0
ADICET BIO INC COM 007002108 14,060 803,900 SH   DFND 0 0 803,900 0
ADIENT PLC ORD SHS G0084W101 4,608 96,248 SH   DFND 0 0 96,248 0
ADS TEC ENERGY PLC *W EXP 12/22/202 G0085J109 15 12,500 SH   DFND 0 0 12,500 0
ADS TEC ENERGY PLC SHS G0085J117 228 25,000 SH   DFND 0 0 25,000 0
ADVANCED MICRO DEVICES INC COM 007903107 30,885 214,627 SH   DFND 0 0 214,627 0
AECOM COM 00766T100 11,881 153,600 SH   DFND 0 0 153,600 0
AEQUI ACQUISITION CORP *W EXP 11/30/202 00775W110 72 133,333 SH   DFND 0 0 133,333 0
AEQUI ACQUISITION CORP COM CL A 00775W102 1,958 200,000 SH   DFND 0 0 200,000 0
AES CORP COM 00130H105 7,693 316,600 SH   DFND 0 0 316,600 0
AEVA TECHNOLOGIES INC COM 00835Q103 1,433 189,500 SH   DFND 0 0 189,500 0
AEYE INC CL A COM 008183105 489 101,000 SH   DFND 0 0 101,000 0
AFFIMED N V COM N01045108 65,440 11,855,151 SH   DFND 0 0 11,855,151 0
AFFIRM HLDGS INC COM CL A 00827B106 9,624 95,700 SH   DFND 0 0 95,700 0
AGEAGLE AERIAL SYS INC NEW COM 00848K101 841 535,400 SH   DFND 0 0 535,400 0
AGREE RLTY CORP COM 008492100 1,613 22,600 SH   DFND 0 0 22,600 0
AGRIFY CORP COM 00853E107 626 68,000 SH   DFND 0 0 68,000 0
AIRSCULPT TECHNOLOGIES INC COM 009496100 2,131 123,947 SH   DFND 0 0 123,947 0
AKERO THERAPEUTICS INC COM 00973Y108 37,192 1,758,501 SH   DFND 0 0 1,758,501 0
ALASKA AIR GROUP INC COM 011659109 48,463 930,197 SH   DFND 0 0 930,197 0
ALBEMARLE CORP COM 012653101 26,510 113,400 SH   DFND 0 0 113,400 0
ALBIREO PHARMA INC COM 01345P106 1,139 48,890 SH   DFND 0 0 48,890 0
ALCOA CORP COM 013872106 10,498 176,200 SH   DFND 0 0 176,200 0
ALGOMA STL GROUP INC COM 015658107 657 60,800 SH   DFND 0 0 60,800 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 4,918 41,400 SH   DFND 0 0 41,400 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 15,680 132,000 SH Call DFND 0 0 132,000 0
ALIGHT INC COM CL A 01626W101 27,501 2,544,000 SH   DFND 0 0 2,544,000 0
ALIGOS THERAPEUTICS INC COM 01626L105 1,311 110,488 SH   DFND 0 0 110,488 0
ALKAMI TECHNOLOGY INC COM 01644J108 371 18,500 SH   DFND 0 0 18,500 0
ALLEGHENY TECHNOLOGIES INC COM 01741R102 8,889 558,000 SH   DFND 0 0 558,000 0
ALLEGIANT TRAVEL CO COM 01748X102 4,152 22,200 SH   DFND 0 0 22,200 0
ALLEGION PLC ORD SHS G0176J109 10,514 79,384 SH   DFND 0 0 79,384 0
ALLETE INC COM NEW 018522300 7,357 110,887 SH   DFND 0 0 110,887 0
ALLIANCE DATA SYSTEMS CORP COM 018581108 18,687 280,710 SH   DFND 0 0 280,710 0
ALLIANT ENERGY CORP COM 018802108 3,919 63,750 SH   DFND 0 0 63,750 0
ALLISON TRANSMISSION HLDGS I COM 01973R101 7,190 197,800 SH   DFND 0 0 197,800 0
ALLY FINL INC COM 02005N100 20,882 438,600 SH   DFND 0 0 438,600 0
ALPHABET INC CAP STK CL A 02079K305 92,404 31,896 SH   DFND 0 0 31,896 0
ALPHABET INC CAP STK CL A 02079K305 14,485 5,000 SH Call DFND 0 0 5,000 0
ALPHABET INC CAP STK CL C 02079K107 15,047 5,200 SH   DFND 0 0 5,200 0
ALPHATEC HLDGS INC COM NEW 02081G201 13,151 1,150,599 SH   DFND 0 0 1,150,599 0
ALTERYX INC COM CL A 02156B103 13,449 222,300 SH   DFND 0 0 222,300 0
ALTIMETER GROWTH CORP 2 COM CL A G0371B109 493 50,000 SH   DFND 0 0 50,000 0
ALTO INGREDIENTS INC COM 021513106 4,062 844,447 SH   DFND 0 0 844,447 0
ALTRIA GROUP INC COM 02209S103 21,628 456,380 SH   DFND 0 0 456,380 0
ALTUS POWER INC COM CL A 02217A102 1,228 117,500 SH   DFND 0 0 117,500 0
AMARIN CORP PLC SPONS ADR NEW 023111206 154 45,665 SH   DFND 0 0 45,665 0
AMAZON COM INC COM 023135106 425,542 127,624 SH   DFND 0 0 127,624 0
AMBARELLA INC SHS G037AX101 23,194 114,320 SH   DFND 0 0 114,320 0
AMCOR PLC ORD G0250X107 2,748 228,800 SH   DFND 0 0 228,800 0
AMEDISYS INC COM 023436108 14,310 88,399 SH   DFND 0 0 88,399 0
AMERICAN AIRLINES GROUP INC NOTE 6.500% 7/0 02376RAF9 20,828 15,000,000 PRN   DFND 0 0 15,000,000 0
AMERICAN AIRLS GROUP INC COM 02376R102 8,441 470,000 SH Put DFND 0 0 470,000 0
AMERICAN EQTY INVT LIFE HLD COM 025676206 23,275 598,010 SH   DFND 0 0 598,010 0
AMERICAN FINL GROUP INC OHIO COM 025932104 51,107 372,177 SH   DFND 0 0 372,177 0
AMERICAN INTL GROUP INC COM NEW 026874784 5,180 91,100 SH   DFND 0 0 91,100 0
AMERIPRISE FINL INC COM 03076C106 45,691 151,465 SH   DFND 0 0 151,465 0
AMERISOURCEBERGEN CORP COM 03073E105 60,252 453,400 SH   DFND 0 0 453,400 0
AMETEK INC COM 031100100 22,513 153,109 SH   DFND 0 0 153,109 0
AMN HEALTHCARE SVCS INC COM 001744101 33,017 269,900 SH   DFND 0 0 269,900 0
AMNEAL PHARMACEUTICALS INC COM STK CL A 03168L105 15,862 3,311,400 SH   DFND 0 0 3,311,400 0
ANALOG DEVICES INC COM 032654105 54,225 308,501 SH   DFND 0 0 308,501 0
ANAPLAN INC COM 03272L108 36,162 788,700 SH   DFND 0 0 788,700 0
ANAPTYSBIO INC COM 032724106 8,936 257,145 SH   DFND 0 0 257,145 0
ANGI INC COM CL A NEW 00183L102 16,145 1,753,014 SH   DFND 0 0 1,753,014 0
ANGIODYNAMICS INC COM 03475V101 21,467 778,354 SH   DFND 0 0 778,354 0
ANNEXON INC COM 03589W102 10,051 874,752 SH   DFND 0 0 874,752 0
ANNEXON INC COM 03589W102 1,678 146,000 SH Call DFND 0 0 146,000 0
ANTERO RESOURCES CORP COM 03674X106 52,774 3,015,676 SH   DFND 0 0 3,015,676 0
ANTERO RESOURCES CORP COM 03674X106 7,000 400,000 SH Call DFND 0 0 400,000 0
ANTHEM INC COM 036752103 20,257 43,700 SH   DFND 0 0 43,700 0
AON PLC SHS CL A G0403H108 10,940 36,400 SH   DFND 0 0 36,400 0
APA CORPORATION COM 03743Q108 12,917 480,356 SH   DFND 0 0 480,356 0
APELLIS PHARMACEUTICALS INC NOTE 3.500% 9/1 03753UAB2 4,538 3,000,000 PRN   DFND 0 0 3,000,000 0
API GROUP CORP COM STK 00187Y100 5,295 205,478 SH   DFND 0 0 205,478 0
APPLIED MATLS INC COM 038222105 116,304 739,097 SH   DFND 0 0 739,097 0
APPLIED THERAPEUTICS INC COM 03828A101 9,970 1,114,000 SH   DFND 0 0 1,114,000 0
APTINYX INC COM 03836N103 448 167,604 SH   DFND 0 0 167,604 0
APTIV PLC SHS G6095L109 1,171 7,100 SH   DFND 0 0 7,100 0
ARCH CAP GROUP LTD ORD G0450A105 9,152 205,900 SH   DFND 0 0 205,900 0
ARCHAEA ENERGY INC COM CL A 03940F103 7,314 400,100 SH   DFND 0 0 400,100 0
ARCHER DANIELS MIDLAND CO COM 039483102 20,838 308,300 SH   DFND 0 0 308,300 0
ARCLIGHT CLEAN TRANSITION II CLASS A ORD SHS G0R21B104 803 80,500 SH   DFND 0 0 80,500 0
ARCONIC CORPORATION COM 03966V107 904 27,400 SH   DFND 0 0 27,400 0
ARCOSA INC COM 039653100 1,054 20,000 SH   DFND 0 0 20,000 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 54,840 2,644,177 SH   DFND 0 0 2,644,177 0
ARES ACQUISITION CORPORATION UNIT 99/99/9999 G33032114 15,888 1,600,000 SH   DFND 0 0 1,600,000 0
ARES MANAGEMENT CORPORATION CL A COM STK 03990B101 2,828 34,800 SH   DFND 0 0 34,800 0
ARGENX SE SPONSORED ADR 04016X101 141,354 403,650 SH   DFND 0 0 403,650 0
ARISTA NETWORKS INC COM 040413106 184,139 1,280,965 SH   DFND 0 0 1,280,965 0
ARK ETF TR INNOVATION ETF 00214Q104 4,730 50,000 SH Put DFND 0 0 50,000 0
ARRAY TECHNOLOGIES INC COM SHS 04271T100 24,957 1,590,600 SH   DFND 0 0 1,590,600 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 2,937 44,292 SH   DFND 0 0 44,292 0
ARTERIS INC COM 04302A104 1,714 81,206 SH   DFND 0 0 81,206 0
ARVINAS INC COM 04335A105 52,668 641,196 SH   DFND 0 0 641,196 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 15,094 112,200 SH   DFND 0 0 112,200 0
ASML HOLDING N V N Y REGISTRY SHS N07059210 5,095 6,400 SH   DFND 0 0 6,400 0
AST SPACEMOBILE INC COM CL A 00217D100 3,773 475,170 SH   DFND 0 0 475,170 0
ASTRAZENECA PLC SPONSORED ADR 046353108 103,068 1,769,400 SH   DFND 0 0 1,769,400 0
ASTRONICS CORP COM 046433108 216 18,000 SH   DFND 0 0 18,000 0
ATARA BIOTHERAPEUTICS INC COM 046513107 72,712 4,613,700 SH   DFND 0 0 4,613,700 0
ATHIRA PHARMA INC COM 04746L104 977 75,000 SH   DFND 0 0 75,000 0
ATLASSIAN CORP PLC CL A G06242104 124,140 325,579 SH   DFND 0 0 325,579 0
ATRICURE INC COM 04963C209 7,265 104,486 SH   DFND 0 0 104,486 0
AURORA INNOVATION INC CLASS A COM 051774107 108 9,562 SH   DFND 0 0 9,562 0
AUTOLIV INC COM 052800109 69,494 672,027 SH   DFND 0 0 672,027 0
AUTONATION INC COM 05329W102 12,744 109,060 SH   DFND 0 0 109,060 0
AUTOZONE INC COM 053332102 53,246 25,399 SH   DFND 0 0 25,399 0
AVALO THERAPEUTICS INC COM 05338F108 10,215 6,008,850 SH   DFND 0 0 6,008,850 0
AVALONBAY CMNTYS INC COM 053484101 1,212 4,800 SH   DFND 0 0 4,800 0
AVANTOR INC COM 05352A100 66,906 1,587,712 SH   DFND 0 0 1,587,712 0
AVERY DENNISON CORP COM 053611109 26,419 121,989 SH   DFND 0 0 121,989 0
AVISTA CORP COM 05379B107 935 22,000 SH   DFND 0 0 22,000 0
AVROBIO INC COM 05455M100 578 150,000 SH   DFND 0 0 150,000 0
AXALTA COATING SYS LTD COM G0750C108 60,876 1,838,043 SH   DFND 0 0 1,838,043 0
AXIS CAP HLDGS LTD SHS G0692U109 29,755 546,273 SH   DFND 0 0 546,273 0
AXON ENTERPRISE INC COM 05464C101 3,491 22,238 SH   DFND 0 0 22,238 0
AZEK CO INC CL A 05478C105 27,975 605,000 SH   DFND 0 0 605,000 0
AZENTA INC COM 114340102 33,864 328,430 SH   DFND 0 0 328,430 0
AZUL S A SPONSR ADR PFD 05501U106 1,299 98,400 SH   DFND 0 0 98,400 0
AZURE PWR GLOBAL LTD SHS V0393H103 4,930 271,600 SH   DFND 0 0 271,600 0
BANDWIDTH INC COM CL A 05988J103 35,614 496,300 SH   DFND 0 0 496,300 0
BARK INC *W EXP 05/01/202 68622E112 15 25,000 SH   DFND 0 0 25,000 0
BATH & BODY WORKS INC COM 070830104 137,854 1,975,267 SH   DFND 0 0 1,975,267 0
BATH & BODY WORKS INC COM 070830104 3,490 50,000 SH Call DFND 0 0 50,000 0
BAXTER INTL INC COM 071813109 66,116 770,226 SH   DFND 0 0 770,226 0
BEAM THERAPEUTICS INC COM 07373V105 3,578 44,900 SH   DFND 0 0 44,900 0
BED BATH & BEYOND INC COM 075896100 1,968 135,000 SH Put DFND 0 0 135,000 0
BELLRING BRANDS INC COM CL A 079823100 50,517 1,770,658 SH   DFND 0 0 1,770,658 0
BERKLEY W R CORP COM 084423102 28,947 351,338 SH   DFND 0 0 351,338 0
BERRY GLOBAL GROUP INC COM 08579W103 24,196 327,942 SH   DFND 0 0 327,942 0
BGC PARTNERS INC CL A 05541T101 16,826 3,618,479 SH   DFND 0 0 3,618,479 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 95,738 1,572,823 SH   DFND 0 0 1,572,823 0
BIGCOMMERCE HLDGS INC COM SER 1 08975P108 10,516 297,300 SH   DFND 0 0 297,300 0
BILL COM HLDGS INC COM 090043100 109,726 440,400 SH   DFND 0 0 440,400 0
BIO RAD LABS INC CL A 090572207 59,734 79,058 SH   DFND 0 0 79,058 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 350 25,272 SH   DFND 0 0 25,272 0
BIOGEN INC COM 09062X103 146,711 611,500 SH   DFND 0 0 611,500 0
BIOGEN INC COM 09062X103 2,399 10,000 SH Call DFND 0 0 10,000 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 72,606 821,796 SH   DFND 0 0 821,796 0
BIONTECH SE SPONSORED ADS 09075V102 22,867 88,700 SH   DFND 0 0 88,700 0
BLACK HILLS CORP COM 092113109 1,567 22,200 SH   DFND 0 0 22,200 0
BLACK KNIGHT INC COM 09215C105 1,235 14,900 SH   DFND 0 0 14,900 0
BLACKBERRY LTD COM 09228F103 487 52,100 SH   DFND 0 0 52,100 0
BLACKSTONE INC COM 09260D107 20,860 161,218 SH   DFND 0 0 161,218 0
BLOOMIN BRANDS INC COM 094235108 6,470 308,410 SH   DFND 0 0 308,410 0
BOOKING HOLDINGS INC COM 09857L108 246,828 102,878 SH   DFND 0 0 102,878 0
BOOT BARN HLDGS INC COM 099406100 6,645 54,000 SH   DFND 0 0 54,000 0
BOOZ ALLEN HAMILTON HLDG COR CL A 099502106 28,617 337,500 SH   DFND 0 0 337,500 0
BOSTON BEER INC CL A 100557107 177 351 SH   DFND 0 0 351 0
BOSTON SCIENTIFIC CORP COM 101137107 80,839 1,902,978 SH   DFND 0 0 1,902,978 0
BOXED INC *W EXP 12/22/202 103174116 60 50,000 SH   DFND 0 0 50,000 0
BP PLC SPONSORED ADR 055622104 13,943 523,597 SH   DFND 0 0 523,597 0
BRIDGEBIO PHARMA INC COM 10806X102 839 50,312 SH   DFND 0 0 50,312 0
BRIDGEBIO PHARMA INC COM 10806X102 512 30,700 SH Call DFND 0 0 30,700 0
BRIDGEBIO PHARMA INC COM 10806X102 871 52,200 SH Put DFND 0 0 52,200 0
BRIDGETOWN HOLDINGS LTD *W EXP 09/30/202 G1355U121 30 33,333 SH   DFND 0 0 33,333 0
BRIXMOR PPTY GROUP INC COM 11120U105 1,814 71,400 SH   DFND 0 0 71,400 0
BROADCOM INC COM 11135F101 11,034 16,583 SH   DFND 0 0 16,583 0
BROWN & BROWN INC COM 115236101 2,137 30,400 SH   DFND 0 0 30,400 0
BROWN FORMAN CORP CL B 115637209 32,705 448,877 SH   DFND 0 0 448,877 0
BRP GROUP INC COM CL A 05589G102 8,097 224,220 SH   DFND 0 0 224,220 0
BTRS HOLDINGS INC COM CL 1 11778X104 2,347 300,100 SH   DFND 0 0 300,100 0
BUILDERS FIRSTSOURCE INC COM 12008R107 23,449 273,580 SH   DFND 0 0 273,580 0
BUMBLE INC COM CL A 12047B105 9,320 275,257 SH   DFND 0 0 275,257 0
BUNGE LIMITED COM G16962105 28,331 303,457 SH   DFND 0 0 303,457 0
BURLINGTON STORES INC COM 122017106 28,432 97,535 SH   DFND 0 0 97,535 0
C H ROBINSON WORLDWIDE INC COM NEW 12541W209 20,354 189,108 SH   DFND 0 0 189,108 0
CABALETTA BIO INC COM 12674W109 3,601 950,000 SH   DFND 0 0 950,000 0
CACI INTL INC CL A 127190304 17,610 65,415 SH   DFND 0 0 65,415 0
CADENCE BANK COM 12740C103 11,460 384,700 SH   DFND 0 0 384,700 0
CADENCE DESIGN SYSTEM INC COM 127387108 10,510 56,400 SH   DFND 0 0 56,400 0
CAESARS ENTERTAINMENT INC NE COM 12769G100 2,446 26,150 SH   DFND 0 0 26,150 0
CALERES INC COM 129500104 12,647 557,641 SH   DFND 0 0 557,641 0
CAMDEN PPTY TR SH BEN INT 133131102 2,269 12,700 SH   DFND 0 0 12,700 0
CAMECO CORP COM 13321L108 5,889 270,000 SH   DFND 0 0 270,000 0
CANADIAN NATL RY CO COM 136375102 29,783 242,444 SH   DFND 0 0 242,444 0
CANADIAN SOLAR INC COM 136635109 5,867 187,500 SH   DFND 0 0 187,500 0
CAPRI HOLDINGS LIMITED SHS G1890L107 49,250 758,750 SH   DFND 0 0 758,750 0
CARA THERAPEUTICS INC COM 140755109 4,364 358,300 SH   DFND 0 0 358,300 0
CARDIFF ONCOLOGY INC COM 14147L108 3,015 501,649 SH   DFND 0 0 501,649 0
CARDLYTICS INC COM 14161W105 687 10,400 SH   DFND 0 0 10,400 0
CAREDX INC COM 14167L103 9,959 218,976 SH   DFND 0 0 218,976 0
CARIBOU BIOSCIENCES INC COM 142038108 4,372 289,739 SH   DFND 0 0 289,739 0
CARLOTZ INC COM CL A 142552108 947 417,400 SH   DFND 0 0 417,400 0
CARLYLE GROUP INC COM 14316J108 62,685 1,141,800 SH   DFND 0 0 1,141,800 0
CARNIVAL CORP COMMON STOCK 143658300 22,132 1,100,000 SH Call DFND 0 0 1,100,000 0
CARTERS INC COM 146229109 9,262 91,501 SH   DFND 0 0 91,501 0
CARVANA CO CL A 146869102 12,748 55,000 SH Call DFND 0 0 55,000 0
CASEYS GEN STORES INC COM 147528103 7,736 39,197 SH   DFND 0 0 39,197 0
CASTLE BIOSCIENCES INC COM 14843C105 20,700 482,852 SH   DFND 0 0 482,852 0
CATALENT INC COM 148806102 59,883 467,730 SH   DFND 0 0 467,730 0
CATCHA INVESTMENT CORP UNIT 99/99/9999 G1962Y128 983 99,340 SH   DFND 0 0 99,340 0
CATERPILLAR INC COM 149123101 12,839 62,100 SH   DFND 0 0 62,100 0
CAZOO GROUP LTD *W EXP 08/26/202 G2007L113 68 75,000 SH   DFND 0 0 75,000 0
CBOE GLOBAL MKTS INC COM 12503M108 26,581 203,842 SH   DFND 0 0 203,842 0
CCC INTELLIGENT SOLUTIONS HL COM 12510Q100 1,834 161,000 SH   DFND 0 0 161,000 0
CDW CORP COM 12514G108 14,417 70,400 SH   DFND 0 0 70,400 0
CELANESE CORP DEL COM 150870103 45,597 271,314 SH   DFND 0 0 271,314 0
CELSIUS HLDGS INC COM NEW 15118V207 2,983 40,000 SH Call DFND 0 0 40,000 0
CENOVUS ENERGY INC COM 15135U109 19,100 1,555,549 SH   DFND 0 0 1,555,549 0
CENTENE CORP DEL COM 15135B101 29,746 361,000 SH   DFND 0 0 361,000 0
CENTENNIAL RESOURCE DEV INC CL A 15136A102 5,846 977,589 SH   DFND 0 0 977,589 0
CENTERPOINT ENERGY INC COM 15189T107 49,808 1,784,588 SH   DFND 0 0 1,784,588 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 12,362 1,097,908 SH   DFND 0 0 1,097,908 0
CENTURY THERAPEUTICS INC COM 15673T100 6,515 410,800 SH   DFND 0 0 410,800 0
CF INDS HLDGS INC COM 125269100 8,180 115,565 SH   DFND 0 0 115,565 0
CHARLES RIV LABS INTL INC COM 159864107 28,974 76,900 SH   DFND 0 0 76,900 0
CHEFS WHSE INC COM 163086101 9,943 298,600 SH   DFND 0 0 298,600 0
CHENIERE ENERGY INC COM NEW 16411R208 113,053 1,114,702 SH   DFND 0 0 1,114,702 0
CHEWY INC CL A 16679L109 5,012 85,000 SH Put DFND 0 0 85,000 0
CHILDRENS PL INC NEW COM 168905107 1,570 19,800 SH   DFND 0 0 19,800 0
CHIMERIX INC COM 16934W106 29,201 4,541,353 SH   DFND 0 0 4,541,353 0
CHINOOK THERAPEUTICS INC COM 16961L106 38,357 2,351,743 SH   DFND 0 0 2,351,743 0
CHIPOTLE MEXICAN GRILL INC COM 169656105 12,360 7,070 SH   DFND 0 0 7,070 0
CHUBB LIMITED COM H1467J104 58,391 302,058 SH   DFND 0 0 302,058 0
CHURCHILL CAPITAL CORP V *W EXP 10/29/202 17144T115 25 25,000 SH   DFND 0 0 25,000 0
CHURCHILL CAPITAL CORP V COM CL A 17144T107 492 50,000 SH   DFND 0 0 50,000 0
CHURCHILL CAPITAL CORP VII UNIT 99/99/9999 17144M201 752 75,000 SH   DFND 0 0 75,000 0
CI FINL CORP COM 125491100 23,500 1,123,592 SH   DFND 0 0 1,123,592 0
CIAN PLC ADS 83418T108 432 35,000 SH   DFND 0 0 35,000 0
CIDARA THERAPEUTICS INC COM 171757107 5,334 4,200,000 SH   DFND 0 0 4,200,000 0
CIENA CORP COM NEW 171779309 2,740 35,600 SH   DFND 0 0 35,600 0
CIGNA CORP NEW COM 125523100 96,383 419,730 SH   DFND 0 0 419,730 0
CINEMARK HLDGS INC NOTE 4.500% 8/1 17243VAB8 22,281 15,500,000 PRN   DFND 0 0 15,500,000 0
CINTAS CORP COM 172908105 12,719 28,700 SH   DFND 0 0 28,700 0
CIPHER MINING INC COM 17253J106 2,172 469,200 SH   DFND 0 0 469,200 0
CISCO SYS INC COM 17275R102 86,380 1,363,100 SH   DFND 0 0 1,363,100 0
CITIZENS FINL GROUP INC COM 174610105 3,780 80,000 SH   DFND 0 0 80,000 0
CLIMATE REAL IMPACT SLUTINS UNIT 99/99/9999 187171202 8,863 889,000 SH   DFND 0 0 889,000 0
CME GROUP INC COM 12572Q105 13,715 60,032 SH   DFND 0 0 60,032 0
CMS ENERGY CORP COM 125896100 29,969 460,700 SH   DFND 0 0 460,700 0
CNH INDL N V SHS N20944109 9,725 500,500 SH   DFND 0 0 500,500 0
COCA COLA CO COM 191216100 167,161 2,823,197 SH   DFND 0 0 2,823,197 0
COCA-COLA EUROPACIFIC PARTNE SHS G25839104 33,127 592,288 SH   DFND 0 0 592,288 0
COGENT BIOSCIENCES INC COM 19240Q201 7,438 866,900 SH   DFND 0 0 866,900 0
COHERUS BIOSCIENCES INC COM 19249H103 5,272 330,300 SH   DFND 0 0 330,300 0
COHN ROBBINS HOLDINGS CORP *W EXP 08/28/202 G23726113 67 83,333 SH   DFND 0 0 83,333 0
COHN ROBBINS HOLDINGS CORP COM CL A G23726105 492 50,000 SH   DFND 0 0 50,000 0
COMERICA INC COM 200340107 3,567 41,000 SH   DFND 0 0 41,000 0
COMMERCIAL METALS CO COM 201723103 8,532 235,100 SH   DFND 0 0 235,100 0
COMMUNITY HEALTH SYS INC NEW COM 203668108 3,893 292,500 SH   DFND 0 0 292,500 0
CONFLUENT INC CLASS A COM 20717M103 47,995 629,523 SH   DFND 0 0 629,523 0
CONMED CORP COM 207410101 4,134 29,162 SH   DFND 0 0 29,162 0
CONOCOPHILLIPS COM 20825C104 43,329 600,285 SH   DFND 0 0 600,285 0
CONSTELLATION BRANDS INC CL A 21036P108 38,456 153,231 SH   DFND 0 0 153,231 0
CONVEY HEALTH SOLUTIONS HLDG COM 21258C108 3,608 431,611 SH   DFND 0 0 431,611 0
CONX CORP *W EXP 10/30/202 212873111 54 62,500 SH   DFND 0 0 62,500 0
COPA HOLDINGS SA CL A P31076105 37,168 449,654 SH   DFND 0 0 449,654 0
COPART INC COM 217204106 19,153 126,323 SH   DFND 0 0 126,323 0
CORVUS PHARMACEUTICALS INC COM 221015100 1,916 795,000 SH   DFND 0 0 795,000 0
COTY INC COM CL A 222070203 138,607 13,200,700 SH   DFND 0 0 13,200,700 0
COTY INC COM CL A 222070203 4,200 400,000 SH Call DFND 0 0 400,000 0
COUCHBASE INC COM 22207T101 8,020 321,296 SH   DFND 0 0 321,296 0
COUPA SOFTWARE INC COM 22266L106 16,643 105,300 SH   DFND 0 0 105,300 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 31,378 1,104,476 SH   DFND 0 0 1,104,476 0
CROCS INC COM 227046109 16,864 131,524 SH   DFND 0 0 131,524 0
CROCS INC COM 227046109 5,129 40,000 SH Call DFND 0 0 40,000 0
CROWDSTRIKE HLDGS INC CL A 22788C105 1,229 6,000 SH   DFND 0 0 6,000 0
CROWN HLDGS INC COM 228368106 32,635 295,022 SH   DFND 0 0 295,022 0
CSX CORP COM 126408103 59,434 1,580,688 SH   DFND 0 0 1,580,688 0
CUBESMART COM 229663109 3,318 58,300 SH   DFND 0 0 58,300 0
CURIS INC COM NEW 231269200 6,867 1,442,543 SH   DFND 0 0 1,442,543 0
CUSTOMERS BANCORP INC COM 23204G100 92 1,400 SH   DFND 0 0 1,400 0
CUTERA INC COM 232109108 5,615 135,900 SH   DFND 0 0 135,900 0
CYCLACEL PHARMACEUTICALS INC COM 23254L603 895 230,000 SH   DFND 0 0 230,000 0
CYMABAY THERAPEUTICS INC COM 23257D103 2,303 681,401 SH   DFND 0 0 681,401 0
CYTOKINETICS INC COM NEW 23282W605 40,359 885,454 SH   DFND 0 0 885,454 0
CYTOMX THERAPEUTICS INC COM 23284F105 27,292 6,303,025 SH   DFND 0 0 6,303,025 0
DANAHER CORPORATION COM 235851102 22,963 69,795 SH   DFND 0 0 69,795 0
DARDEN RESTAURANTS INC COM 237194105 30,928 205,308 SH   DFND 0 0 205,308 0
DATADOG INC CL A COM 23804L103 78,539 440,958 SH   DFND 0 0 440,958 0
DATADOG INC CL A COM 23804L103 6,234 35,000 SH Call DFND 0 0 35,000 0
DAVE & BUSTERS ENTMT INC COM 238337109 10,055 261,855 SH   DFND 0 0 261,855 0
DAVITA INC COM 23918K108 13,820 121,486 SH   DFND 0 0 121,486 0
DECARBONIZATION PLUS ACQU II COM CL A 242794105 3,988 400,000 SH   DFND 0 0 400,000 0
DECKERS OUTDOOR CORP COM 243537107 2,984 8,147 SH   DFND 0 0 8,147 0
DEEP LAKE CAPITAL ACQUSTN CO UNIT 01/04/2026 G27029126 2,508 250,000 SH   DFND 0 0 250,000 0
DEERE & CO COM 244199105 7,599 22,161 SH   DFND 0 0 22,161 0
DELEK US HLDGS INC NEW COM 24665A103 12,052 804,000 SH   DFND 0 0 804,000 0
DELL TECHNOLOGIES INC CL C 24703L202 33,073 588,800 SH   DFND 0 0 588,800 0
DENTSPLY SIRONA INC COM 24906P109 67,083 1,202,416 SH   DFND 0 0 1,202,416 0
DESPEGAR COM CORP ORD SHS G27358103 8,012 818,400 SH   DFND 0 0 818,400 0
DIGITAL RLTY TR INC COM 253868103 30,808 174,185 SH   DFND 0 0 174,185 0
DIGITALBRIDGE GROUP INC CL A COM 25401T108 20,742 2,490,000 SH   DFND 0 0 2,490,000 0
DIGITALOCEAN HLDGS INC COM 25402D102 61,388 764,200 SH   DFND 0 0 764,200 0
DISCOVERY INC COM SER C 25470F302 1,113 48,600 SH   DFND 0 0 48,600 0
DISH NETWORK CORPORATION CL A 25470M109 3,812 117,500 SH Put DFND 0 0 117,500 0
DISH NETWORK CORPORATION NOTE 12/1 25470MAF6 25,025 25,000,000 PRN   DFND 0 0 25,000,000 0
DISH NETWORK CORPORATION NOTE 2.375% 3/1 25470MAD1 10,576 11,000,000 PRN   DFND 0 0 11,000,000 0
DISNEY WALT CO COM 254687106 17,933 115,780 SH   DFND 0 0 115,780 0
DISRUPTIVE ACQUISITION CORP UNIT 03/06/2026 G2770Y110 1,542 150,000 SH   DFND 0 0 150,000 0
DOLLAR TREE INC COM 256746108 27,052 192,512 SH   DFND 0 0 192,512 0
DOMINION ENERGY INC COM 25746U109 87,657 1,115,800 SH   DFND 0 0 1,115,800 0
DOORDASH INC CL A 25809K105 10,784 72,424 SH   DFND 0 0 72,424 0
DOORDASH INC CL A 25809K105 5,956 40,000 SH Call DFND 0 0 40,000 0
DOVER CORP COM 260003108 15,879 87,441 SH   DFND 0 0 87,441 0
DPCM CAP INC *W EXP 10/14/202 23344P119 20 33,333 SH   DFND 0 0 33,333 0
DRIVEN BRANDS HLDGS INC COM 26210V102 18,915 562,599 SH   DFND 0 0 562,599 0
DT MIDSTREAM INC COMMON STOCK 23345M107 63,856 1,330,878 SH   DFND 0 0 1,330,878 0
DTE ENERGY CO COM 233331107 45,533 380,900 SH   DFND 0 0 380,900 0
DUKE ENERGY CORP NEW COM NEW 26441C204 56,198 535,727 SH   DFND 0 0 535,727 0
DUPONT DE NEMOURS INC COM 26614N102 3,488 43,174 SH   DFND 0 0 43,174 0
DYNE THERAPEUTICS INC COM 26818M108 14,920 1,254,800 SH   DFND 0 0 1,254,800 0
E L F BEAUTY INC COM 26856L103 1,039 31,300 SH   DFND 0 0 31,300 0
EAGLE MATLS INC COM 26969P108 12,694 76,260 SH   DFND 0 0 76,260 0
EASTMAN CHEM CO COM 277432100 11,546 95,495 SH   DFND 0 0 95,495 0
EATON CORP PLC SHS G29183103 17,857 103,329 SH   DFND 0 0 103,329 0
EHEALTH INC COM 28238P109 949 37,200 SH   DFND 0 0 37,200 0
ELASTIC N V ORD SHS N14506104 76,574 622,095 SH   DFND 0 0 622,095 0
ELECTRIC LAST MILE SOLUTNS I CLASS A COM 28489L104 611 90,000 SH   DFND 0 0 90,000 0
ELECTRONIC ARTS INC COM 285512109 79,299 601,203 SH   DFND 0 0 601,203 0
ELEDON PHARMACEUTICALS INC COM 28617K101 1,903 431,435 SH   DFND 0 0 431,435 0
ELEVATE CREDIT INC COM 28621V101 552 186,000 SH   DFND 0 0 186,000 0
EMBARK TECHNOLOGY INC *W EXP 11/10/202 29079J111 651 324,666 SH   DFND 0 0 324,666 0
EMBARK TECHNOLOGY INC COM 29079J103 2,386 274,844 SH   DFND 0 0 274,844 0
EMBRAER S.A. SPONSORED ADS 29082A107 5,439 306,422 SH   DFND 0 0 306,422 0
EMPLOYERS HLDGS INC COM 292218104 3,083 74,496 SH   DFND 0 0 74,496 0
ENBRIDGE INC COM 29250N105 11,473 293,527 SH   DFND 0 0 293,527 0
ENDEAVOR GROUP HLDGS INC CL A COM 29260Y109 144 4,121 SH   DFND 0 0 4,121 0
ENERPLUS CORP COM 292766102 4,632 438,971 SH   DFND 0 0 438,971 0
ENOVIX CORPORATION COM 293594107 497 18,213 SH   DFND 0 0 18,213 0
ENPHASE ENERGY INC COM 29355A107 279 1,525 SH   DFND 0 0 1,525 0
ENSTAR GROUP LIMITED SHS G3075P101 12,003 48,481 SH   DFND 0 0 48,481 0
EPAM SYS INC COM 29414B104 9,083 13,588 SH   DFND 0 0 13,588 0
EQT CORP COM 26884L109 16,041 735,475 SH   DFND 0 0 735,475 0
EQUIFAX INC COM 294429105 37,506 128,100 SH   DFND 0 0 128,100 0
EQUINOR ASA SPONSORED ADR 29446M102 67,539 2,565,111 SH   DFND 0 0 2,565,111 0
EQUITABLE HLDGS INC COM 29452E101 12,738 388,464 SH   DFND 0 0 388,464 0
EQUITY RESIDENTIAL SH BEN INT 29476L107 2,190 24,200 SH   DFND 0 0 24,200 0
ERICSSON ADR B SEK 10 294821608 26,153 2,406,000 SH   DFND 0 0 2,406,000 0
ESPERION THERAPEUTICS INC NE NOTE 4.000%11/1 29664WAB1 3,705 7,000,000 PRN   DFND 0 0 7,000,000 0
ESSENTIAL UTILS INC COM 29670G102 44,213 823,484 SH   DFND 0 0 823,484 0
ESSEX PPTY TR INC COM 297178105 1,338 3,800 SH   DFND 0 0 3,800 0
ETF SER SOLUTIONS US GLB JETS 26922A842 1,055 50,000 SH Call DFND 0 0 50,000 0
EVERGY INC COM 30034W106 1,156 16,844 SH   DFND 0 0 16,844 0
EVOLENT HEALTH INC CL A 30050B101 11,808 426,736 SH   DFND 0 0 426,736 0
EVOLUS INC COM 30052C107 2,022 310,600 SH   DFND 0 0 310,600 0
EXECUTIVE NETWORK PARTNERING *W EXP 09/25/202 30158L118 42 62,500 SH   DFND 0 0 62,500 0
EXELIXIS INC COM 30161Q104 77,181 4,222,146 SH   DFND 0 0 4,222,146 0
EXELON CORP COM 30161N101 58,193 1,007,500 SH   DFND 0 0 1,007,500 0
F-STAR THERAPEUTICS INC COM 30315R107 4,926 981,249 SH   DFND 0 0 981,249 0
F5 INC COM 315616102 49,480 202,200 SH   DFND 0 0 202,200 0
FABRINET SHS G3323L100 37,513 316,649 SH   DFND 0 0 316,649 0
FAIR ISAAC CORP COM 303250104 27,555 63,540 SH   DFND 0 0 63,540 0
FARFETCH LTD ORD SH CL A 30744W107 6,195 185,300 SH   DFND 0 0 185,300 0
FASTLY INC CL A 31188V100 16,165 456,000 SH Put DFND 0 0 456,000 0
FATHOM DIGITAL MFG CORP *W EXP 12/22/202 31189Y111 11 12,500 SH   DFND 0 0 12,500 0
FATHOM HOLDINGS INC COM 31189V109 1,023 50,000 SH   DFND 0 0 50,000 0
FEDERAL RLTY INVT TR SH BEN INT NEW 313747206 1,322 9,700 SH   DFND 0 0 9,700 0
FEDEX CORP COM 31428X106 112,801 436,132 SH   DFND 0 0 436,132 0
FERROGLOBE PLC SHS G33856108 5 800 SH   DFND 0 0 800 0
FIBROGEN INC COM 31572Q808 52,630 3,732,594 SH   DFND 0 0 3,732,594 0
FIDELITY NATL INFORMATION SV COM 31620M106 88,335 809,300 SH   DFND 0 0 809,300 0
FIELD TRIP HEALTH LTD COM 31656R102 3,554 1,467,346 SH   DFND 0 0 1,467,346 0
FIFTH THIRD BANCORP COM 316773100 2,373 54,500 SH   DFND 0 0 54,500 0
FIRST WATCH RESTAURANT GROUP COM 33748L101 503 30,000 SH   DFND 0 0 30,000 0
FIRSTENERGY CORP COM 337932107 32,184 773,830 SH   DFND 0 0 773,830 0
FIVE BELOW INC COM 33829M101 33,370 161,294 SH   DFND 0 0 161,294 0
FIVE BELOW INC COM 33829M101 6,207 30,000 SH Call DFND 0 0 30,000 0
FIVE9 INC COM 338307101 24,567 178,900 SH   DFND 0 0 178,900 0
FLOOR & DECOR HLDGS INC CL A 339750101 55,435 426,394 SH   DFND 0 0 426,394 0
FLUENCE ENERGY INC COM CL A 34379V103 4,678 131,541 SH   DFND 0 0 131,541 0
FOGHORN THERAPEUTICS INC COM 344174107 8,770 383,472 SH   DFND 0 0 383,472 0
FORMA THERAPEUTICS HLDGS INC SHS 34633R104 8,474 595,900 SH   DFND 0 0 595,900 0
FORTUNE BRANDS HOME & SEC IN COM 34964C106 207 1,938 SH   DFND 0 0 1,938 0
FRANKLIN RESOURCES INC COM 354613101 2,230 66,600 SH   DFND 0 0 66,600 0
FREEPORT-MCMORAN INC CL B 35671D857 20,852 499,700 SH   DFND 0 0 499,700 0
FREYR BATTERY SHS L4135L100 7,339 656,400 SH   DFND 0 0 656,400 0
FRONTIER COMMUNICATIONS PARE COM 35909D109 28,122 953,600 SH   DFND 0 0 953,600 0
FRONTIER GROUP HLDGS INC COM 35909R108 7,537 555,400 SH   DFND 0 0 555,400 0
FULCRUM THERAPEUTICS INC COM 359616109 8,945 505,655 SH   DFND 0 0 505,655 0
FULGENT GENETICS INC COM 359664109 4,396 43,700 SH   DFND 0 0 43,700 0
FUSION PHARMACEUTICALS INC COM 36118A100 4,374 1,048,956 SH   DFND 0 0 1,048,956 0
G III APPAREL GROUP LTD COM 36237H101 11,842 428,436 SH   DFND 0 0 428,436 0
GALAPAGOS NV SPON ADR 36315X101 42,114 763,900 SH   DFND 0 0 763,900 0
GALLAGHER ARTHUR J & CO COM 363576109 73,377 432,467 SH   DFND 0 0 432,467 0
GARMIN LTD SHS H2906T109 1,049 7,700 SH   DFND 0 0 7,700 0
GCM GROSVENOR INC COM CL A 36831E108 2,555 243,323 SH   DFND 0 0 243,323 0
GENERAC HLDGS INC COM 368736104 35,651 101,303 SH   DFND 0 0 101,303 0
GENERAC HLDGS INC COM 368736104 5,279 15,000 SH Call DFND 0 0 15,000 0
GENERAL DYNAMICS CORP COM 369550108 12,050 57,800 SH   DFND 0 0 57,800 0
GENERAL ELECTRIC CO COM NEW 369604301 1,615 17,100 SH   DFND 0 0 17,100 0
GENERAL MTRS CO COM 37045V100 142,261 2,426,427 SH   DFND 0 0 2,426,427 0
GENERAL MTRS CO COM 37045V100 32,247 550,000 SH Call DFND 0 0 550,000 0
GENIUS SPORTS LIMITED SHARES CL A G3934V109 1,673 220,100 SH   DFND 0 0 220,100 0
GENOCEA BIOSCIENCES INC COM NEW 372427401 3,077 2,652,974 SH   DFND 0 0 2,652,974 0
GFL ENVIRONMENTAL INC SUB VTG SHS 36168Q104 13,526 357,355 SH   DFND 0 0 357,355 0
GH RESEARCH PLC ORDINARY SHARES G3855L106 7,256 311,000 SH   DFND 0 0 311,000 0
GILDAN ACTIVEWEAR INC COM 375916103 4,627 109,151 SH   DFND 0 0 109,151 0
GILEAD SCIENCES INC COM 375558103 36,305 500,000 SH Put DFND 0 0 500,000 0
GLAUKOS CORP COM 377322102 29,779 670,100 SH   DFND 0 0 670,100 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 15,461 350,600 SH   DFND 0 0 350,600 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 22,050 500,000 SH Call DFND 0 0 500,000 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 5,370 183,471 SH   DFND 0 0 183,471 0
GLOBAL PMTS INC COM 37940X102 61,007 451,300 SH   DFND 0 0 451,300 0
GLOBAL SYNERGY ACQUISIT CORP UNIT 01/01/2024 G3934J114 1,004 100,000 SH   DFND 0 0 100,000 0
GLOBUS MED INC CL A 379577208 18,804 260,450 SH   DFND 0 0 260,450 0
GODADDY INC CL A 380237107 64,799 763,600 SH   DFND 0 0 763,600 0
GOHEALTH INC COM CL A 38046W105 1,680 443,400 SH   DFND 0 0 443,400 0
GOL LINHAS AEREAS INTELIGENT SPON ADR PFD NEW 38045R206 588 97,200 SH   DFND 0 0 97,200 0
GOLAR LNG LTD SHS G9456A100 23,675 1,910,828 SH   DFND 0 0 1,910,828 0
GOLAR LNG LTD SHS G9456A100 30,031 2,423,800 SH Call DFND 0 0 2,423,800 0
GOODRX HLDGS INC COM CL A 38246G108 8,179 250,269 SH   DFND 0 0 250,269 0
GOODYEAR TIRE & RUBR CO COM 382550101 25,917 1,215,621 SH   DFND 0 0 1,215,621 0
GOPRO INC CL A 38268T103 2,492 241,700 SH   DFND 0 0 241,700 0
GRAB HOLDINGS LIMITED *W EXP 12/01/202 G4124C117 42 20,000 SH   DFND 0 0 20,000 0
GRAINGER W W INC COM 384802104 32,467 62,649 SH   DFND 0 0 62,649 0
GRAPHIC PACKAGING HLDG CO COM 388689101 786 40,300 SH   DFND 0 0 40,300 0
GREEN PLAINS INC COM 393222104 13,871 399,048 SH   DFND 0 0 399,048 0
GROWTH CAP ACQUISITION CORP CL A 39986V107 14,812 1,491,609 SH   DFND 0 0 1,491,609 0
GUARDANT HEALTH INC COM 40131M109 8,212 82,100 SH   DFND 0 0 82,100 0
GUESS INC COM 401617105 11,308 477,514 SH   DFND 0 0 477,514 0
GULFPORT ENERGY CORP COMMON SHARES 402635502 2,433 33,778 SH   DFND 0 0 33,778 0
GXO LOGISTICS INCORPORATED COMMON STOCK 36262G101 18 200 SH   DFND 0 0 200 0
HAIN CELESTIAL GROUP INC COM 405217100 37,565 881,599 SH   DFND 0 0 881,599 0
HALLIBURTON CO COM 406216101 850 37,152 SH   DFND 0 0 37,152 0
HALLMARK FINL SVCS INC COM NEW 40624Q203 77 17,600 SH   DFND 0 0 17,600 0
HALOZYME THERAPEUTICS INC COM 40637H109 8,525 212,000 SH   DFND 0 0 212,000 0
HARLEY DAVIDSON INC COM 412822108 1,703 45,176 SH   DFND 0 0 45,176 0
HARPOON THERAPEUTICS INC COM 41358P106 4,908 650,000 SH   DFND 0 0 650,000 0
HARTFORD FINL SVCS GROUP INC COM 416515104 12,814 185,600 SH   DFND 0 0 185,600 0
HASBRO INC COM 418056107 16,161 158,784 SH   DFND 0 0 158,784 0
HASHICORP INC COM CL A 418100103 1,821 20,000 SH   DFND 0 0 20,000 0
HAWAIIAN HOLDINGS INC COM 419879101 503 27,400 SH   DFND 0 0 27,400 0
HCI GROUP INC COM 40416E103 16,315 195,300 SH   DFND 0 0 195,300 0
HEALTHCARE RLTY TR COM 421946104 1,152 36,400 SH   DFND 0 0 36,400 0
HEALTHCARE SERVICES ACQU COR *W EXP 99/99/999 42227K112 39 75,000 SH   DFND 0 0 75,000 0
HEALTHCARE SERVICES ACQU COR COM CL A 42227K104 976 100,000 SH   DFND 0 0 100,000 0
HEALTHEQUITY INC COM 42226A107 6,065 137,100 SH   DFND 0 0 137,100 0
HELEN OF TROY LTD COM G4388N106 22,076 90,300 SH   DFND 0 0 90,300 0
HELMERICH & PAYNE INC COM 423452101 2,205 93,028 SH   DFND 0 0 93,028 0
HENRY SCHEIN INC COM 806407102 4,750 61,268 SH   DFND 0 0 61,268 0
HERSHEY CO COM 427866108 54,705 282,755 SH   DFND 0 0 282,755 0
HERTZ GLOBAL HLDGS INC COM NEW 42806J700 19,600 784,327 SH   DFND 0 0 784,327 0
HESKA CORP COM RESTRC NEW 42805E306 9,358 51,277 SH   DFND 0 0 51,277 0
HEXCEL CORP NEW COM 428291108 2,530 48,846 SH   DFND 0 0 48,846 0
HIBBETT INC COM 428567101 2,374 33,000 SH   DFND 0 0 33,000 0
HIGHLAND TRANSCEND PARTNERS *W EXP 99/99/999 G44690124 133 83,333 SH   DFND 0 0 83,333 0
HIGHLAND TRANSCEND PARTNERS COM CL A G44690108 992 100,000 SH   DFND 0 0 100,000 0
HILTON WORLDWIDE HLDGS INC COM 43300A203 22,244 142,597 SH   DFND 0 0 142,597 0
HIMAX TECHNOLOGIES INC SPONSORED ADR 43289P106 7,144 446,800 SH   DFND 0 0 446,800 0
HIPPO HLDGS INC *W EXP 99/99/999 433539111 6 12,000 SH   DFND 0 0 12,000 0
HIPPO HLDGS INC COMMON STOCK 433539103 752 265,800 SH   DFND 0 0 265,800 0
HOLOGIC INC COM 436440101 40,324 526,700 SH   DFND 0 0 526,700 0
HORMEL FOODS CORP COM 440452100 14,856 304,374 SH   DFND 0 0 304,374 0
HOST HOTELS & RESORTS INC COM 44107P104 11,139 640,516 SH   DFND 0 0 640,516 0
HOWMET AEROSPACE INC COM 443201108 28,402 892,300 SH   DFND 0 0 892,300 0
HP INC COM 40434L105 3,767 100,000 SH Put DFND 0 0 100,000 0
HUAZHU GROUP LTD SPONSORED ADS 44332N106 8,129 217,700 SH   DFND 0 0 217,700 0
HUB GROUP INC CL A 443320106 11,137 132,200 SH   DFND 0 0 132,200 0
HUMANA INC COM 444859102 3,247 7,000 SH   DFND 0 0 7,000 0
HUMANCO ACQUISITION CORP *W EXP 99/99/999 44487N117 94 125,000 SH   DFND 0 0 125,000 0
HUMANCO ACQUISITION CORP COM CL A 44487N109 1,467 150,000 SH   DFND 0 0 150,000 0
HUNTINGTON INGALLS INDS INC COM 446413106 14,398 77,100 SH   DFND 0 0 77,100 0
HYATT HOTELS CORP COM CL A 448579102 54,653 569,900 SH   DFND 0 0 569,900 0
I MAB SPONSORED ADS 44975P103 801 16,900 SH   DFND 0 0 16,900 0
IAA INC COM 449253103 43,265 854,700 SH   DFND 0 0 854,700 0
ICHOR HOLDINGS SHS G4740B105 17,261 375,000 SH   DFND 0 0 375,000 0
ICU MED INC COM 44930G107 109,395 460,921 SH   DFND 0 0 460,921 0
IDACORP INC COM 451107106 4,623 40,800 SH   DFND 0 0 40,800 0
IDEAYA BIOSCIENCES INC COM 45166A102 31,923 1,350,400 SH   DFND 0 0 1,350,400 0
ILLINOIS TOOL WKS INC COM 452308109 3,638 14,739 SH   DFND 0 0 14,739 0
ILLUMINA INC COM 452327109 30,425 79,974 SH   DFND 0 0 79,974 0
IMMUNIC INC COM 4525EP101 6,938 725,000 SH   DFND 0 0 725,000 0
IMMUNOCORE HLDGS PLC ADS 45258D105 425 12,400 SH   DFND 0 0 12,400 0
IMMUNOVANT INC COM 45258J102 7,672 900,500 SH   DFND 0 0 900,500 0
IMPEL NEUROPHARMA INC COM 45258K109 1,802 208,760 SH   DFND 0 0 208,760 0
IMPERIAL OIL LTD COM NEW 453038408 13,610 377,000 SH   DFND 0 0 377,000 0
IMPINJ INC COM 453204109 8,810 99,327 SH   DFND 0 0 99,327 0
INARI MED INC COM 45332Y109 40,843 447,500 SH   DFND 0 0 447,500 0
INCYTE CORP COM 45337C102 17,543 239,000 SH   DFND 0 0 239,000 0
INDEPENDENCE RLTY TR INC COM 45378A106 447 17,300 SH   DFND 0 0 17,300 0
INFINERA CORP COM 45667G103 15,747 1,642,000 SH   DFND 0 0 1,642,000 0
INFINITY PHARMACEUTICALS INC COM 45665G303 1,734 770,552 SH   DFND 0 0 770,552 0
INFORMATICA INC COM CL A 45674M101 3,753 101,500 SH   DFND 0 0 101,500 0
INFRA AND ENERGY ALTRNTIVE I COM 45686J104 11,040 1,200,000 SH   DFND 0 0 1,200,000 0
INGREDION INC COM 457187102 15,930 164,841 SH   DFND 0 0 164,841 0
INNOVATIVE INDL PPTYS INC COM 45781V101 2,655 10,100 SH   DFND 0 0 10,100 0
INNOVIZ TECHNOLOGIES LTD SHS M5R635108 688 108,500 SH   DFND 0 0 108,500 0
INNOVIZ TECHNOLOGIES LTD SHS M5R635108 1,913 301,800 SH Call DFND 0 0 301,800 0
INSMED INC COM PAR $.01 457669307 65,356 2,399,252 SH   DFND 0 0 2,399,252 0
INSPIRE MED SYS INC COM 457730109 66,132 287,456 SH   DFND 0 0 287,456 0
INTEGRA LIFESCIENCES HLDGS C NOTE 0.500% 8/1 457985AM1 7,380 6,750,000 PRN   DFND 0 0 6,750,000 0
INTEL CORP COM 458140100 7,725 150,000 SH Call DFND 0 0 150,000 0
INTERACTIVE BROKERS GROUP IN COM CL A 45841N107 6,012 75,700 SH   DFND 0 0 75,700 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 8,376 514,200 SH   DFND 0 0 514,200 0
INTUIT COM 461202103 55,639 86,500 SH   DFND 0 0 86,500 0
INTUITIVE SURGICAL INC COM NEW 46120E602 69,369 193,066 SH   DFND 0 0 193,066 0
INVESCO QQQ TR UNIT SER 1 46090E103 21,882 55,000 SH Put DFND 0 0 55,000 0
IONIS PHARMACEUTICALS INC COM 462222100 1,643 53,981 SH   DFND 0 0 53,981 0
IRHYTHM TECHNOLOGIES INC COM 450056106 4,107 34,900 SH   DFND 0 0 34,900 0
IRIS ENERGY LTD ORDINARY SHARES Q4982L109 7,194 444,900 SH   DFND 0 0 444,900 0
ISHARES INC MSCI BRAZIL ETF 464286400 21,614 770,000 SH Call DFND 0 0 770,000 0
ISHARES TR 20 YR TR BD ETF 464287432 222 1,500 SH   DFND 0 0 1,500 0
ISHARES TR CHINA LG-CAP ETF 464287184 15,729 430,000 SH Put DFND 0 0 430,000 0
ISHARES TR CORE S&P500 ETF 464287200 454,094 952,000 SH   DFND 0 0 952,000 0
ISHARES TR GL CLEAN ENE ETF 464288224 2,540 120,000 SH   DFND 0 0 120,000 0
ISHARES TR IBOXX HI YD ETF 464288513 10,876 125,000 SH   DFND 0 0 125,000 0
ISHARES TR IBOXX INV CP ETF 464287242 19,977 150,746 SH   DFND 0 0 150,746 0
ISHARES TR ISHS 1-5YR INVS 464288646 29,975 556,327 SH   DFND 0 0 556,327 0
ISHARES TR MSCI UK ETF NEW 46435G334 4,971 150,000 SH   DFND 0 0 150,000 0
ISHARES TR RUS 2000 VAL ETF 464287630 4,982 30,000 SH   DFND 0 0 30,000 0
ISHARES TR RUSSELL 2000 ETF 464287655 7,786 35,000 SH Put DFND 0 0 35,000 0
ITEOS THERAPEUTICS INC COM 46565G104 4,890 105,030 SH   DFND 0 0 105,030 0
ITRON INC COM 465741106 939 13,700 SH   DFND 0 0 13,700 0
JABIL INC COM 466313103 204,887 2,912,400 SH   DFND 0 0 2,912,400 0
JACK CREEK INVESTMENT CORP UNIT 10/01/2023 G4989X107 1,000 100,000 SH   DFND 0 0 100,000 0
JAMES RIV GROUP LTD COM G5005R107 10,993 381,578 SH   DFND 0 0 381,578 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 122,791 963,824 SH   DFND 0 0 963,824 0
JBG SMITH PPTYS COM 46590V100 3 100 SH   DFND 0 0 100 0
JD.COM INC SPON ADR CL A 47215P106 38,358 547,427 SH   DFND 0 0 547,427 0
JFROG LTD ORD SHS M6191J100 50,473 1,699,443 SH   DFND 0 0 1,699,443 0
JOHNSON & JOHNSON COM 478160104 2,220 12,977 SH   DFND 0 0 12,977 0
JOHNSON CTLS INTL PLC SHS G51502105 39,881 490,487 SH   DFND 0 0 490,487 0
JOUNCE THERAPEUTICS INC COM 481116101 2,120 253,931 SH   DFND 0 0 253,931 0
JUMIA TECHNOLOGIES AG SPONSORED ADS 48138M105 3,486 305,783 SH   DFND 0 0 305,783 0
JUMIA TECHNOLOGIES AG SPONSORED ADS 48138M105 1,710 150,000 SH Call DFND 0 0 150,000 0
JUNIPER NETWORKS INC COM 48203R104 24,751 693,100 SH   DFND 0 0 693,100 0
KARUNA THERAPEUTICS INC COM 48576A100 12,196 93,097 SH   DFND 0 0 93,097 0
KEMPER CORP COM 488401100 1,211 20,600 SH   DFND 0 0 20,600 0
KEROS THERAPEUTICS INC COM 492327101 3,688 63,028 SH   DFND 0 0 63,028 0
KEURIG DR PEPPER INC COM 49271V100 30,021 814,451 SH   DFND 0 0 814,451 0
KEZAR LIFE SCIENCES INC COM 49372L100 35,204 2,105,490 SH   DFND 0 0 2,105,490 0
KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101 4,689 398,352 SH   DFND 0 0 398,352 0
KINSALE CAP GROUP INC COM 49714P108 12,018 50,519 SH   DFND 0 0 50,519 0
KIRBY CORP COM 497266106 5,823 98,005 SH   DFND 0 0 98,005 0
KKR & CO INC COM 48251W104 22,082 296,400 SH   DFND 0 0 296,400 0
KOHLS CORP COM 500255104 2,470 50,000 SH Put DFND 0 0 50,000 0
KONINKLIJKE PHILIPS N V NY REGIS SHS NEW 500472303 6,821 185,100 SH   DFND 0 0 185,100 0
KOSMOS ENERGY LTD COM 500688106 5,071 1,465,513 SH   DFND 0 0 1,465,513 0
KRAFT HEINZ CO COM 500754106 28,748 800,784 SH   DFND 0 0 800,784 0
KRYSTAL BIOTECH INC COM 501147102 129,838 1,856,156 SH   DFND 0 0 1,856,156 0
KYMERA THERAPEUTICS INC COM 501575104 3,695 58,200 SH   DFND 0 0 58,200 0
LA Z BOY INC COM 505336107 625 17,200 SH   DFND 0 0 17,200 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 22,495 71,591 SH   DFND 0 0 71,591 0
LAM RESEARCH CORP COM 512807108 108,664 151,100 SH   DFND 0 0 151,100 0
LAMAR ADVERTISING CO NEW CL A 512816109 18,577 153,148 SH   DFND 0 0 153,148 0
LANDEC CORP COM 514766104 1,965 177,019 SH   DFND 0 0 177,019 0
LANDS END INC NEW COM 51509F105 349 17,800 SH   DFND 0 0 17,800 0
LARIMAR THERAPEUTICS INC COM 517125100 2,125 196,896 SH   DFND 0 0 196,896 0
LAS VEGAS SANDS CORP COM 517834107 7,989 212,240 SH   DFND 0 0 212,240 0
LAVA THERAPEUTICS NV SHS N51517105 655 119,152 SH   DFND 0 0 119,152 0
LEAR CORP COM NEW 521865204 13,672 74,729 SH   DFND 0 0 74,729 0
LENDINGCLUB CORP COM NEW 52603A208 39,834 1,647,395 SH   DFND 0 0 1,647,395 0
LENDINGTREE INC NEW COM 52603B107 18,807 153,400 SH   DFND 0 0 153,400 0
LENNAR CORP CL A 526057104 22,049 189,817 SH   DFND 0 0 189,817 0
LENNOX INTL INC COM 526107107 10,099 31,134 SH   DFND 0 0 31,134 0
LEVI STRAUSS & CO NEW CL A COM STK 52736R102 3,042 121,546 SH   DFND 0 0 121,546 0
LHC GROUP INC COM 50187A107 10,855 79,100 SH   DFND 0 0 79,100 0
LIBERTY GLOBAL PLC SHS CL A G5480U104 6,359 229,251 SH   DFND 0 0 229,251 0
LIBERTY GLOBAL PLC SHS CL C G5480U120 10,699 380,900 SH   DFND 0 0 380,900 0
LIBERTY MEDIA ACQUISITION CO UNIT 01/22/2026 53073L203 1,006 95,000 SH   DFND 0 0 95,000 0
LIBERTY OILFIELD SVCS INC COM CL A 53115L104 6,518 672,000 SH   DFND 0 0 672,000 0
LIFE STORAGE INC COM 53223X107 230 1,500 SH   DFND 0 0 1,500 0
LIGAND PHARMACEUTICALS INC COM NEW 53220K504 8,356 54,100 SH   DFND 0 0 54,100 0
LILIUM N V *W EXP 09/14/202 N52586117 92 75,000 SH   DFND 0 0 75,000 0
LILLY ELI & CO COM 532457108 77,424 280,300 SH   DFND 0 0 280,300 0
LINCOLN NATL CORP IND COM 534187109 8,997 131,800 SH   DFND 0 0 131,800 0
LINDE PLC SHS G5494J103 2,009 5,800 SH   DFND 0 0 5,800 0
LITHIA MTRS INC COM 536797103 2,519 8,483 SH   DFND 0 0 8,483 0
LIVANOVA PLC SHS G5509L101 2,308 26,400 SH   DFND 0 0 26,400 0
LIVE NATION ENTERTAINMENT IN COM 538034109 43,751 365,538 SH   DFND 0 0 365,538 0
LIVE NATION ENTERTAINMENT IN NOTE 2.500% 3/1 538034AQ2 27,163 15,000,000 PRN   DFND 0 0 15,000,000 0
LIVENT CORP COM 53814L108 658 27,000 SH   DFND 0 0 27,000 0
LIVEPERSON INC COM 538146101 17,826 499,062 SH   DFND 0 0 499,062 0
LIVERAMP HLDGS INC COM 53815P108 6,608 137,820 SH   DFND 0 0 137,820 0
LOUISIANA PAC CORP COM 546347105 10,013 127,800 SH   DFND 0 0 127,800 0
LPL FINL HLDGS INC COM 50212V100 33,827 211,300 SH   DFND 0 0 211,300 0
LUCID GROUP INC COM 549498103 7,278 191,266 SH   DFND 0 0 191,266 0
LUMENTUM HLDGS INC COM 55024U109 86,372 816,600 SH   DFND 0 0 816,600 0
LXP INDUSTRIAL TRUST COM 529043101 2,999 192,000 SH   DFND 0 0 192,000 0
M & T BK CORP COM 55261F104 3,194 20,800 SH   DFND 0 0 20,800 0
MACROGENICS INC COM 556099109 20,226 1,260,161 SH   DFND 0 0 1,260,161 0
MACYS INC COM 55616P104 29,653 1,132,665 SH   DFND 0 0 1,132,665 0
MADISON SQUARE GRDN SPRT COR CL A 55825T103 3,405 19,600 SH   DFND 0 0 19,600 0
MAGNA INTL INC COM 559222401 47,509 586,969 SH   DFND 0 0 586,969 0
MAGNA INTL INC COM 559222401 4,047 50,000 SH Call DFND 0 0 50,000 0
MANPOWERGROUP INC WIS COM 56418H100 4,283 44,000 SH   DFND 0 0 44,000 0
MARATHON OIL CORP COM 565849106 42,068 2,562,016 SH   DFND 0 0 2,562,016 0
MARAVAI LIFESCIENCES HLDGS I COM CL A 56600D107 16,379 390,900 SH   DFND 0 0 390,900 0
MARKEL CORP COM 570535104 48,362 39,191 SH   DFND 0 0 39,191 0
MARQETA INC CLASS A COM 57142B104 1,375 80,100 SH   DFND 0 0 80,100 0
MARRIOTT VACATIONS WORLDWIDE COM 57164Y107 31,802 188,200 SH   DFND 0 0 188,200 0
MARSH & MCLENNAN COS INC COM 571748102 10,183 58,584 SH   DFND 0 0 58,584 0
MARTIN MARIETTA MATLS INC COM 573284106 14,025 31,837 SH   DFND 0 0 31,837 0
MARVELL TECHNOLOGY INC COM 573874104 90,745 1,037,206 SH   DFND 0 0 1,037,206 0
MASCO CORP COM 574599106 41,980 597,836 SH   DFND 0 0 597,836 0
MASTEC INC COM 576323109 1,273 13,800 SH   DFND 0 0 13,800 0
MASTERCARD INCORPORATED CL A 57636Q104 184,033 512,171 SH   DFND 0 0 512,171 0
MATCH GROUP INC NEW COM 57667L107 53,019 400,900 SH   DFND 0 0 400,900 0
MATTEL INC COM 577081102 27,963 1,296,980 SH   DFND 0 0 1,296,980 0
MATTERPORT INC COM CL A 577096100 6,398 310,000 SH Put DFND 0 0 310,000 0
MCDONALDS CORP COM 580135101 32,479 121,157 SH   DFND 0 0 121,157 0
MCKESSON CORP COM 58155Q103 38,976 156,800 SH   DFND 0 0 156,800 0
MEDIAALPHA INC CL A 58450V104 110 7,100 SH   DFND 0 0 7,100 0
MEDTECH ACQUISITION CORP *W EXP 12/22/202 58507N113 69 133,333 SH   DFND 0 0 133,333 0
MEDTECH ACQUISITION CORP COM CL A 58507N105 1,976 200,000 SH   DFND 0 0 200,000 0
MEI PHARMA INC COM NEW 55279B202 7,477 2,800,500 SH   DFND 0 0 2,800,500 0
MELCO RESORTS AND ENTMNT LTD ADR 585464100 251 24,700 SH   DFND 0 0 24,700 0
MERCADOLIBRE INC COM 58733R102 42,875 31,797 SH   DFND 0 0 31,797 0
MERCADOLIBRE INC COM 58733R102 10,113 7,500 SH Call DFND 0 0 7,500 0
MERCK & CO INC COM 58933Y105 3,997 52,149 SH   DFND 0 0 52,149 0
MEREO BIOPHARMA GROUP PLC ADS 589492107 16,976 10,610,000 SH   DFND 0 0 10,610,000 0
MERIT MED SYS INC COM 589889104 12,404 199,100 SH   DFND 0 0 199,100 0
MERRIMACK PHARMACEUTICALS IN COM NEW 590328209 1,336 341,685 SH   DFND 0 0 341,685 0
MERSANA THERAPEUTICS INC COM 59045L106 5,089 818,100 SH   DFND 0 0 818,100 0
MERUS N V COM N5749R100 3,846 120,941 SH   DFND 0 0 120,941 0
META PLATFORMS INC CL A 30303M102 200,670 596,612 SH   DFND 0 0 596,612 0
META PLATFORMS INC CL A 30303M102 10,931 32,500 SH Call DFND 0 0 32,500 0
METLIFE INC COM 59156R108 21,101 337,669 SH   DFND 0 0 337,669 0
METTLER TOLEDO INTERNATIONAL COM 592688105 2,352 1,386 SH   DFND 0 0 1,386 0
MGIC INVT CORP WIS COM 552848103 1,707 118,400 SH   DFND 0 0 118,400 0
MGM RESORTS INTERNATIONAL COM 552953101 10,575 235,628 SH   DFND 0 0 235,628 0
MICRON TECHNOLOGY INC COM 595112103 206,353 2,215,275 SH   DFND 0 0 2,215,275 0
MICROSOFT CORP COM 594918104 118,824 353,306 SH   DFND 0 0 353,306 0
MICROSOFT CORP COM 594918104 16,816 50,000 SH Call DFND 0 0 50,000 0
MID-AMER APT CMNTYS INC COM 59522J103 3,097 13,500 SH   DFND 0 0 13,500 0
MINISO GROUP HLDG LTD SPONSORED ADS 66981J102 1,873 181,100 SH   DFND 0 0 181,100 0
MIRATI THERAPEUTICS INC COM 60468T105 70,388 479,845 SH   DFND 0 0 479,845 0
MIRUM PHARMACEUTICALS INC COM 604749101 5,022 314,843 SH   DFND 0 0 314,843 0
MOELIS & CO CL A 60786M105 869 13,900 SH   DFND 0 0 13,900 0
MOGO INC COM 60800C109 7,167 2,095,572 SH   DFND 0 0 2,095,572 0
MOHAWK INDS INC COM 608190104 1,291 7,088 SH   DFND 0 0 7,088 0
MONDAY COM LTD SHS M7S64H106 55,786 180,700 SH   DFND 0 0 180,700 0
MONGODB INC CL A 60937P106 23,609 44,600 SH   DFND 0 0 44,600 0
MONSTER BEVERAGE CORP NEW COM 61174X109 99,142 1,032,299 SH   DFND 0 0 1,032,299 0
MORGAN STANLEY COM NEW 617446448 5,114 52,100 SH   DFND 0 0 52,100 0
MORPHIC HLDG INC COM 61775R105 21,629 456,500 SH   DFND 0 0 456,500 0
MOSAIC CO NEW COM 61945C103 9,823 250,000 SH   DFND 0 0 250,000 0
MOTIVE CAPITAL CORP *W EXP 12/31/202 G6293A111 85 83,333 SH   DFND 0 0 83,333 0
MOTIVE CAPITAL CORP SHS CL A G6293A103 984 100,000 SH   DFND 0 0 100,000 0
MOTOROLA SOLUTIONS INC COM NEW 620076307 49,998 184,020 SH   DFND 0 0 184,020 0
MSC INDL DIRECT INC CL A 553530106 210 2,500 SH   DFND 0 0 2,500 0
MSCI INC COM 55354G100 980 1,600 SH   DFND 0 0 1,600 0
MSD ACQUISITION CORP UNIT 03/25/2026 G5709C117 20,320 2,000,000 SH   DFND 0 0 2,000,000 0
MURPHY OIL CORP COM 626717102 10,677 408,938 SH   DFND 0 0 408,938 0
MYNARIC AG SPON ADS 62857X101 1,492 117,294 SH   DFND 0 0 117,294 0
NABORS INDUSTRIES LTD SHS G6359F137 24 300 SH   DFND 0 0 300 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 11,757 278,400 SH   DFND 0 0 278,400 0
NATERA INC COM 632307104 99,029 1,060,382 SH   DFND 0 0 1,060,382 0
NATIONAL ENERGY SERVICES REU SHS G6375R107 372 39,406 SH   DFND 0 0 39,406 0
NATIONAL STORAGE AFFILIATES COM SHS BEN IN 637870106 69 1,000 SH   DFND 0 0 1,000 0
NAVITAS SEMICONDUCTOR CORP COM 63942X106 8,721 512,700 SH   DFND 0 0 512,700 0
NCR CORP NEW COM 62886E108 20,148 501,200 SH   DFND 0 0 501,200 0
NEKTAR THERAPEUTICS COM 640268108 6,246 462,300 SH   DFND 0 0 462,300 0
NEOGEN CORP COM 640491106 4,001 88,100 SH   DFND 0 0 88,100 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 4,872 1,010,790 SH   DFND 0 0 1,010,790 0
NERDWALLET INC COM CL A 64082B102 9,099 585,134 SH   DFND 0 0 585,134 0
NETEASE INC SPONSORED ADS 64110W102 29,170 286,600 SH   DFND 0 0 286,600 0
NEUBASE THERAPEUTICS INC COM 64132K102 3,513 1,250,000 SH   DFND 0 0 1,250,000 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 44,951 527,774 SH   DFND 0 0 527,774 0
NEUROPACE INC COM 641288105 1,373 136,200 SH   DFND 0 0 136,200 0
NEW FORTRESS ENERGY INC COM CL A 644393100 18,203 754,047 SH   DFND 0 0 754,047 0
NEW ORIENTAL ED & TECHNOLOGY SPON ADR 647581107 11,892 5,662,649 SH   DFND 0 0 5,662,649 0
NEW YORK CMNTY BANCORP INC COM 649445103 7,433 608,800 SH   DFND 0 0 608,800 0
NEW YORK TIMES CO CL A 650111107 3,574 74,000 SH   DFND 0 0 74,000 0
NEXTDECADE CORP COM 65342K105 995 349,199 SH   DFND 0 0 349,199 0
NEXTDOOR HOLDINGS INC COM CL A 65345M108 5,050 640,002 SH   DFND 0 0 640,002 0
NEXTERA ENERGY INC COM 65339F101 31,472 337,100 SH   DFND 0 0 337,100 0
NEXTERA ENERGY PARTNERS LP COM UNIT PART IN 65341B106 1,430 16,941 SH   DFND 0 0 16,941 0
NEXTGEN HEALTHCARE INC COM 65343C102 5,091 286,200 SH   DFND 0 0 286,200 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 58,406 3,297,898 SH   DFND 0 0 3,297,898 0
NICE LTD SPONSORED ADR 653656108 134,798 444,000 SH   DFND 0 0 444,000 0
NIKE INC CL B 654106103 2,700 16,202 SH   DFND 0 0 16,202 0
NISOURCE INC COM 65473P105 6,822 247,100 SH   DFND 0 0 247,100 0
NMI HLDGS INC CL A 629209305 1,106 50,600 SH   DFND 0 0 50,600 0
NOKIA CORP SPONSORED ADR 654902204 36,982 5,945,700 SH   DFND 0 0 5,945,700 0
NORTHERN OIL AND GAS INC MN COM 665531307 5,688 276,399 SH   DFND 0 0 276,399 0
NORTHERN TR CORP COM 665859104 311 2,600 SH   DFND 0 0 2,600 0
NORWEGIAN CRUISE LINE HLDG L SHS G66721104 1,058 51,000 SH   DFND 0 0 51,000 0
NORWEGIAN CRUISE LINE HLDG L SHS G66721104 311 15,000 SH Put DFND 0 0 15,000 0
NOV INC COM 62955J103 11,968 883,217 SH   DFND 0 0 883,217 0
NOVARTIS AG SPONSORED ADR 66987V109 13,374 152,900 SH   DFND 0 0 152,900 0
NU HLDGS LTD ORD SHS CL A G6683N103 1,407 150,000 SH   DFND 0 0 150,000 0
NUCOR CORP COM 670346105 11,415 100,000 SH Call DFND 0 0 100,000 0
NURIX THERAPEUTICS INC COM 67080M103 3,953 136,550 SH   DFND 0 0 136,550 0
NUTRIEN LTD COM 67077M108 1,970 26,200 SH   DFND 0 0 26,200 0
NUVEI CORPORATION SUB VTG SHS 67079A102 60,178 927,414 SH   DFND 0 0 927,414 0
NVENT ELECTRIC PLC SHS G6700G107 2,240 58,938 SH   DFND 0 0 58,938 0
NVIDIA CORPORATION COM 67066G104 39,206 133,304 SH   DFND 0 0 133,304 0
OASIS PETROLEUM INC COM NEW 674215207 9,789 77,700 SH   DFND 0 0 77,700 0
OCCIDENTAL PETE CORP COM 674599105 16,077 554,569 SH   DFND 0 0 554,569 0
OCEANEERING INTL INC COM 675232102 957 84,600 SH   DFND 0 0 84,600 0
ODONATE THERAPEUTICS INC COM 676079106 68 50,000 SH   DFND 0 0 50,000 0
OFFERPAD SOLUTIONS INC *W EXP 10/16/202 67623L117 143 133,333 SH   DFND 0 0 133,333 0
OGE ENERGY CORP COM 670837103 29,273 762,702 SH   DFND 0 0 762,702 0
OKTA INC CL A 679295105 49,676 221,600 SH   DFND 0 0 221,600 0
OLAPLEX HLDGS INC COM 679369108 36,536 1,254,242 SH   DFND 0 0 1,254,242 0
OLIN CORP COM PAR $1 680665205 12,654 220,000 SH   DFND 0 0 220,000 0
OLO INC CL A 68134L109 1,136 54,600 SH   DFND 0 0 54,600 0
OMEGA THERAPEUTICS INC COMMON STOCK 68217N105 1,466 129,389 SH   DFND 0 0 129,389 0
OMNICHANNEL ACQUISITION CORP *W EXP 12/30/202 68218L116 74 125,000 SH   DFND 0 0 125,000 0
OMNICOM GROUP INC COM 681919106 9,749 133,060 SH   DFND 0 0 133,060 0
ONEMAIN HLDGS INC COM 68268W103 5,004 100,000 SH   DFND 0 0 100,000 0
OPEN LENDING CORP COM CL A 68373J104 11,594 515,754 SH   DFND 0 0 515,754 0
OPENDOOR TECHNOLOGIES INC COM 683712103 45,323 3,102,207 SH   DFND 0 0 3,102,207 0
OPENDOOR TECHNOLOGIES INC COM 683712103 13,660 935,000 SH Call DFND 0 0 935,000 0
OPKO HEALTH INC COM 68375N103 32,006 6,654,123 SH   DFND 0 0 6,654,123 0
OPPFI INC *W EXP 07/20/202 68386H111 44 64,883 SH   DFND 0 0 64,883 0
OPTIMIZERX CORP COM NEW 68401U204 9,012 145,100 SH   DFND 0 0 145,100 0
OPTION CARE HEALTH INC COM NEW 68404L201 10,301 362,210 SH   DFND 0 0 362,210 0
OREILLY AUTOMOTIVE INC COM 67103H107 36,705 51,973 SH   DFND 0 0 51,973 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107 5,134 240,000 SH   DFND 0 0 240,000 0
OSHKOSH CORP COM 688239201 16,784 148,916 SH   DFND 0 0 148,916 0
OUTFRONT MEDIA INC COM 69007J106 1,434 53,453 SH   DFND 0 0 53,453 0
OVINTIV INC COM 69047Q102 99,710 2,958,747 SH   DFND 0 0 2,958,747 0
OYSTER PT PHARMA INC COM 69242L106 38,372 2,101,441 SH   DFND 0 0 2,101,441 0
PACCAR INC COM 693718108 12,511 141,750 SH   DFND 0 0 141,750 0
PACWEST BANCORP DEL COM 695263103 11,618 257,200 SH   DFND 0 0 257,200 0
PAGERDUTY INC COM 69553P100 17,375 500,000 SH   DFND 0 0 500,000 0
PALO ALTO NETWORKS INC COM 697435105 29,566 53,103 SH   DFND 0 0 53,103 0
PALOMAR HLDGS INC COM 69753M105 15,929 245,938 SH   DFND 0 0 245,938 0
PAPA JOHNS INTL INC COM 698813102 7,688 57,600 SH   DFND 0 0 57,600 0
PARDES BIOSCIENCES INC COM 69945Q105 2,247 137,234 SH   DFND 0 0 137,234 0
PATTERSON COS INC COM 703395103 10,261 349,600 SH   DFND 0 0 349,600 0
PAYA HOLDINGS INC COM CL A 70434P103 3,062 482,900 SH   DFND 0 0 482,900 0
PAYCHEX INC COM 704326107 25,600 187,549 SH   DFND 0 0 187,549 0
PAYMENTUS HOLDINGS INC COM CL A 70439P108 1,273 36,400 SH   DFND 0 0 36,400 0
PAYONEER GLOBAL INC *W EXP 06/25/202 70451X112 534 225,000 SH   DFND 0 0 225,000 0
PDC ENERGY INC COM 69327R101 6,604 135,377 SH   DFND 0 0 135,377 0
PEABODY ENGR CORP COM 704551100 1 100 SH   DFND 0 0 100 0
PEBBLEBROOK HOTEL TR COM 70509V100 18,946 846,916 SH   DFND 0 0 846,916 0
PEGASYSTEMS INC COM 705573103 3,976 35,561 SH   DFND 0 0 35,561 0
PELOTON INTERACTIVE INC CL A COM 70614W100 4,828 135,000 SH Call DFND 0 0 135,000 0
PENTAIR PLC SHS G7S00T104 8,355 114,399 SH   DFND 0 0 114,399 0
PENUMBRA INC COM 70975L107 45,741 159,200 SH   DFND 0 0 159,200 0
PERFORMANCE FOOD GROUP CO COM 71377A103 67,629 1,473,712 SH   DFND 0 0 1,473,712 0
PERRIGO CO PLC SHS G97822103 30,766 790,900 SH   DFND 0 0 790,900 0
PERSHING SQUARE TONTINE HLDG *W EXP 07/24/202 71531R117 14 10,555 SH   DFND 0 0 10,555 0
PERSONALIS INC COM 71535D106 2,878 201,713 SH   DFND 0 0 201,713 0
PETCO HEALTH & WELLNESS CO I COM 71601V105 14,118 713,379 SH   DFND 0 0 713,379 0
PETIQ INC COM CL A 71639T106 14,887 655,546 SH   DFND 0 0 655,546 0
PETMED EXPRESS INC COM 716382106 2,344 92,813 SH   DFND 0 0 92,813 0
PG&E CORP COM 69331C108 63,803 5,255,600 SH   DFND 0 0 5,255,600 0
PHILLIPS 66 COM 718546104 84,311 1,163,556 SH   DFND 0 0 1,163,556 0
PHYSICIANS RLTY TR COM 71943U104 1,164 61,800 SH   DFND 0 0 61,800 0
PINDUODUO INC NOTE 12/0 722304AC6 18,581 20,500,000 PRN   DFND 0 0 20,500,000 0
PING IDENTITY HLDG CORP COM 72341T103 46,073 2,013,700 SH   DFND 0 0 2,013,700 0
PINNACLE WEST CAP CORP COM 723484101 16,130 228,500 SH   DFND 0 0 228,500 0
PINTEREST INC CL A 72352L106 57,517 1,582,300 SH   DFND 0 0 1,582,300 0
PIONEER MERGER CORP *W EXP 01/07/202 G7S24C111 108 166,666 SH   DFND 0 0 166,666 0
PIONEER MERGER CORP CL A SHS G7S24C103 4,935 499,998 SH   DFND 0 0 499,998 0
PIONEER NAT RES CO COM 723787107 51,483 283,062 SH   DFND 0 0 283,062 0
PLAINS GP HLDGS L P LTD PARTNR INT A 72651A207 20,002 1,972,600 SH   DFND 0 0 1,972,600 0
PLAYTIKA HLDG CORP COM 72815L107 6,083 351,800 SH   DFND 0 0 351,800 0
PLIANT THERAPEUTICS INC COM 729139105 15,324 1,135,100 SH   DFND 0 0 1,135,100 0
PLUG POWER INC COM NEW 72919P202 8,034 284,600 SH   DFND 0 0 284,600 0
PLYMOUTH INDL REIT INC COM 729640102 6 200 SH   DFND 0 0 200 0
PNM RES INC COM 69349H107 8,894 195,000 SH   DFND 0 0 195,000 0
POLARITYTE INC COM 731094108 1,468 2,500,000 SH   DFND 0 0 2,500,000 0
POPULATION HEALTH INVS CO IN *W EXP 10/01/202 G71716115 26 50,000 SH   DFND 0 0 50,000 0
POSHMARK INC COM CL A 73739W104 6,706 393,800 SH   DFND 0 0 393,800 0
POST HLDGS INC COM 737446104 18,114 160,689 SH   DFND 0 0 160,689 0
PRAXIS PRECISION MEDICINES I COM 74006W108 28,494 1,446,393 SH   DFND 0 0 1,446,393 0
PRIVIA HEALTH GROUP INC COM 74276R102 42,442 1,640,600 SH   DFND 0 0 1,640,600 0
PROASSURANCE CORP COM 74267C106 645 25,500 SH   DFND 0 0 25,500 0
PROCTER AND GAMBLE CO COM 742718109 18,383 112,380 SH   DFND 0 0 112,380 0
PROGRESS ACQUISITION CORP UNIT 12/25/2025 74327P204 439 43,900 SH   DFND 0 0 43,900 0
PROMETHEUS BIOSCIENCES INC COM 74349U108 5,320 134,537 SH   DFND 0 0 134,537 0
PROQR THRAPEUTICS N V SHS EURO N71542109 3,693 461,000 SH   DFND 0 0 461,000 0
PROSPECTOR CAPITAL CORP UNIT 01/01/2030 G7273A121 2,582 260,063 SH   DFND 0 0 260,063 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 82,756 2,419,763 SH   DFND 0 0 2,419,763 0
PROTERRA INC COM 74374T109 59 6,723 SH   DFND 0 0 6,723 0
PROTHENA CORP PLC SHS G72800108 9,544 193,200 SH   DFND 0 0 193,200 0
PTC THERAPEUTICS INC COM 69366J200 14,144 355,100 SH   DFND 0 0 355,100 0
PUBLIC STORAGE COM 74460D109 3,071 8,200 SH   DFND 0 0 8,200 0
PULMONX CORP COM 745848101 10,195 317,907 SH   DFND 0 0 317,907 0
PURECYCLE TECHNOLOGIES INC COM 74623V103 3,986 416,500 SH   DFND 0 0 416,500 0
PURPLE BIOTECH LTD SPONSORED ADS 74638P109 1,086 279,294 SH   DFND 0 0 279,294 0
PURPLE INNOVATION INC COM 74640Y106 460 34,700 SH   DFND 0 0 34,700 0
PVH CORPORATION COM 693656100 38,127 357,499 SH   DFND 0 0 357,499 0
QIAGEN NV SHS NEW N72482123 5,191 93,400 SH   DFND 0 0 93,400 0
QORVO INC COM 74736K101 112,304 718,100 SH   DFND 0 0 718,100 0
QUALCOMM INC COM 747525103 23,791 130,097 SH   DFND 0 0 130,097 0
QUALTRICS INTL INC COM CL A 747601201 6,793 191,905 SH   DFND 0 0 191,905 0
QUANTERIX CORP COM 74766Q101 7,827 184,600 SH   DFND 0 0 184,600 0
QUIDEL CORP COM 74838J101 35,880 265,800 SH   DFND 0 0 265,800 0
R1 RCM INC COM 749397105 35,668 1,399,300 SH   DFND 0 0 1,399,300 0
RADIAN GROUP INC COM 750236101 1,864 88,200 SH   DFND 0 0 88,200 0
RADIUS GLOBAL INFRASTRCTRE I COM CL A 750481103 3,920 243,500 SH   DFND 0 0 243,500 0
RADNET INC COM 750491102 11,291 375,000 SH   DFND 0 0 375,000 0
RAYMOND JAMES FINL INC COM 754730109 32,302 321,733 SH   DFND 0 0 321,733 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 59,391 690,113 SH   DFND 0 0 690,113 0
REDBALL ACQUISITION CORP *W EXP 08/17/202 G7417R113 41 33,333 SH   DFND 0 0 33,333 0
REDBALL ACQUISITION CORP COM CL A G7417R105 992 99,999 SH   DFND 0 0 99,999 0
REE AUTOMOTIVE LTD CLASS A ORD SHS M8287R103 1,300 234,300 SH   DFND 0 0 234,300 0
REGAL REXNORD CORPORATION COM 758750103 5,327 31,300 SH   DFND 0 0 31,300 0
RELIANCE STEEL & ALUMINUM CO COM 759509102 1,849 11,400 SH   DFND 0 0 11,400 0
RELMADA THERAPEUTICS INC COM 75955J402 21,320 946,313 SH   DFND 0 0 946,313 0
REMITLY GLOBAL INC COM 75960P104 9,153 443,876 SH   DFND 0 0 443,876 0
RENEW ENERGY GLOBAL PLC *W EXP 08/30/202 G7500M120 185 117,290 SH   DFND 0 0 117,290 0
RENEW ENERGY GLOBAL PLC CL A SHS G7500M104 6,913 888,612 SH   DFND 0 0 888,612 0
REPARE THERAPEUTICS INC COM 760273102 601 28,500 SH   DFND 0 0 28,500 0
REPAY HLDGS CORP COM CL A 76029L100 2,881 157,700 SH   DFND 0 0 157,700 0
REPLIGEN CORP COM 759916109 29,845 112,691 SH   DFND 0 0 112,691 0
REPLIMUNE GROUP INC COM 76029N106 9,219 340,200 SH   DFND 0 0 340,200 0
REPUBLIC SVCS INC COM 760759100 30,205 216,600 SH   DFND 0 0 216,600 0
RESEARCH FRONTIERS INC COM 760911107 42 24,445 SH   DFND 0 0 24,445 0
RESOLUTE FST PRODS INC COM 76117W109 6,840 447,946 SH   DFND 0 0 447,946 0
REVANCE THERAPEUTICS INC COM 761330109 14,386 881,482 SH   DFND 0 0 881,482 0
RH COM 74967X103 50,314 93,879 SH   DFND 0 0 93,879 0
RIBBIT LEAP LTD *W EXP 09/09/202 G7552B113 52 40,000 SH   DFND 0 0 40,000 0
RIBBIT LEAP LTD SHS CL A G7552B105 1,502 150,000 SH   DFND 0 0 150,000 0
RINGCENTRAL INC CL A 76680R206 125,955 672,300 SH   DFND 0 0 672,300 0
RIOT BLOCKCHAIN INC COM 767292105 2,488 111,400 SH   DFND 0 0 111,400 0
RIVIAN AUTOMOTIVE INC COM CL A 76954A103 19,027 183,500 SH   DFND 0 0 183,500 0
RLI CORP COM 749607107 1,648 14,700 SH   DFND 0 0 14,700 0
ROBERT HALF INTL INC COM 770323103 15,375 137,864 SH   DFND 0 0 137,864 0
ROCKET COS INC COM CL A 77311W101 1,289 92,100 SH   DFND 0 0 92,100 0
ROCKWELL AUTOMATION INC COM 773903109 9,939 28,490 SH   DFND 0 0 28,490 0
ROKU INC COM CL A 77543R102 61,890 271,210 SH   DFND 0 0 271,210 0
ROKU INC COM CL A 77543R102 20,196 88,500 SH Call DFND 0 0 88,500 0
ROLLINS INC COM 775711104 2,935 85,800 SH   DFND 0 0 85,800 0
ROOT INC COM CL A 77664L108 652 210,400 SH   DFND 0 0 210,400 0
ROPER TECHNOLOGIES INC COM 776696106 2,168 4,407 SH   DFND 0 0 4,407 0
ROSS STORES INC COM 778296103 10,725 93,850 SH   DFND 0 0 93,850 0
ROVER GROUP INC *W EXP 10/01/202 77936F111 37 15,000 SH   DFND 0 0 15,000 0
ROYAL CARIBBEAN GROUP COM V7780T103 5,952 77,397 SH   DFND 0 0 77,397 0
ROYAL DUTCH SHELL PLC SPON ADR B 780259107 42,713 985,296 SH   DFND 0 0 985,296 0
ROYAL DUTCH SHELL PLC SPONS ADR A 780259206 33,656 775,490 SH   DFND 0 0 775,490 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 13,394 336,100 SH   DFND 0 0 336,100 0
RYAN SPECIALTY GROUP HLDGS I CL A 78351F107 8,445 209,295 SH   DFND 0 0 209,295 0
S&P GLOBAL INC COM 78409V104 95,700 202,785 SH   DFND 0 0 202,785 0
SABRE CORP COM 78573M104 13,097 1,524,700 SH   DFND 0 0 1,524,700 0
SABRE CORP COM 78573M104 1,289 150,000 SH Call DFND 0 0 150,000 0
SABRE CORP COM 78573M104 472 55,000 SH Put DFND 0 0 55,000 0
SABRE GLBL INC NOTE 4.000% 4/1 78573NAE2 13,726 10,000,000 PRN   DFND 0 0 10,000,000 0
SAGE THERAPEUTICS INC COM 78667J108 14,332 336,900 SH   DFND 0 0 336,900 0
SAILPOINT TECHNOLOGIES HLDGS COM 78781P105 18,321 379,000 SH   DFND 0 0 379,000 0
SALESFORCE COM INC COM 79466L302 52,122 205,100 SH   DFND 0 0 205,100 0
SAMSARA INC COM CL A 79589L106 12,228 435,000 SH   DFND 0 0 435,000 0
SANOFI SPONSORED ADR 80105N105 90,906 1,814,500 SH   DFND 0 0 1,814,500 0
SAREPTA THERAPEUTICS INC COM 803607100 103,666 1,151,209 SH   DFND 0 0 1,151,209 0
SAREPTA THERAPEUTICS INC COM 803607100 1,486 16,500 SH Call DFND 0 0 16,500 0
SAREPTA THERAPEUTICS INC DBCV 1.500%11/1 803607AB6 13,948 9,507,000 PRN   DFND 0 0 9,507,000 0
SBA COMMUNICATIONS CORP NEW CL A 78410G104 19,451 50,000 SH   DFND 0 0 50,000 0
SCION TECH GROWTH I *W EXP 11/01/202 G31067112 20 33,333 SH   DFND 0 0 33,333 0
SCION TECH GROWTH I CL A SHS G31067104 488 50,000 SH   DFND 0 0 50,000 0
SCULPTOR ACQUISITION CORP I UNIT 99/99/9999 G7T983129 1,001 100,000 SH   DFND 0 0 100,000 0
SEAGEN INC COM 81181C104 98,106 634,581 SH   DFND 0 0 634,581 0
SEALED AIR CORP NEW COM 81211K100 32,042 474,900 SH   DFND 0 0 474,900 0
SEAWORLD ENTMT INC COM 81282V100 33,883 522,406 SH   DFND 0 0 522,406 0
SELECT SECTOR SPDR TR ENERGY 81369Y506 24,836 447,500 SH   DFND 0 0 447,500 0
SELECT SECTOR SPDR TR ENERGY 81369Y506 70,485 1,270,000 SH Call DFND 0 0 1,270,000 0
SELECT SECTOR SPDR TR FINANCIAL 81369Y605 10,348 265,000 SH   DFND 0 0 265,000 0
SELECT SECTOR SPDR TR FINANCIAL 81369Y605 976 25,000 SH Put DFND 0 0 25,000 0
SELECTQUOTE INC COM 816307300 1,860 205,273 SH   DFND 0 0 205,273 0
SEMPRA COM 816851109 17,620 133,200 SH   DFND 0 0 133,200 0
SENTINELONE INC CL A 81730H109 46,168 914,400 SH   DFND 0 0 914,400 0
SERVICENOW INC COM 81762P102 125,809 193,817 SH   DFND 0 0 193,817 0
SHARECARE INC *W EXP 07/01/202 81948W112 52 83,333 SH   DFND 0 0 83,333 0
SHARECARE INC COM CL A 81948W104 3,348 745,661 SH   DFND 0 0 745,661 0
SHIFT4 PMTS INC CL A 82452J109 12,299 212,300 SH   DFND 0 0 212,300 0
SHOCKWAVE MED INC COM 82489T104 8,037 45,067 SH   DFND 0 0 45,067 0
SIGNATURE BK NEW YORK N Y COM 82669G104 68,764 212,582 SH   DFND 0 0 212,582 0
SIGNET JEWELERS LIMITED SHS G81276100 33,807 388,453 SH   DFND 0 0 388,453 0
SIGNIFY HEALTH INC CL A COM 82671G100 2,463 173,200 SH   DFND 0 0 173,200 0
SILENCE THERAPEUTICS PLC ADS 82686Q101 5,973 250,000 SH   DFND 0 0 250,000 0
SILVERBOX ENGAGED MERGER CO COM CL A 82836L101 7,958 784,000 SH   DFND 0 0 784,000 0
SILVERGATE CAP CORP CL A 82837P408 14,064 94,900 SH   DFND 0 0 94,900 0
SIMON PPTY GROUP INC NEW COM 828806109 1,710 10,700 SH   DFND 0 0 10,700 0
SIMON PROPERTY GRP ACQ HOLDI UNIT 99/99/9999 82880R202 495 50,000 SH   DFND 0 0 50,000 0
SIX FLAGS ENTMT CORP NEW COM 83001A102 33,006 775,150 SH   DFND 0 0 775,150 0
SKECHERS U S A INC CL A 830566105 26,759 616,575 SH   DFND 0 0 616,575 0
SL GREEN RLTY CORP COM 78440X804 4,481 62,500 SH   DFND 0 0 62,500 0
SM ENERGY CO COM 78454L100 13,986 474,421 SH   DFND 0 0 474,421 0
SMARTRENT INC COM CL A 83193G107 3,363 347,418 SH   DFND 0 0 347,418 0
SMARTSHEET INC COM CL A 83200N103 48,739 629,300 SH   DFND 0 0 629,300 0
SMITH & NEPHEW PLC SPDN ADR NEW 83175M205 11,913 344,100 SH   DFND 0 0 344,100 0
SNAP INC CL A 83304A106 52,196 1,109,849 SH   DFND 0 0 1,109,849 0
SNAP INC CL A 83304A106 4,703 100,000 SH Call DFND 0 0 100,000 0
SNOWFLAKE INC CL A 833445109 102,473 302,504 SH   DFND 0 0 302,504 0
SNOWFLAKE INC CL A 833445109 1,694 5,000 SH Call DFND 0 0 5,000 0
SOLAREDGE TECHNOLOGIES INC COM 83417M104 30,633 109,182 SH   DFND 0 0 109,182 0
SOMALOGIC INC *W EXP 08/31/202 83444K113 2,603 779,487 SH   DFND 0 0 779,487 0
SOMALOGIC INC CLASS A COM 83444K105 43,309 3,720,666 SH   DFND 0 0 3,720,666 0
SONENDO INC COM 835431107 115 20,000 SH   DFND 0 0 20,000 0
SONO GROUP N V COM N81409109 2,648 275,000 SH   DFND 0 0 275,000 0
SONY GROUP CORPORATION SPONSORED ADR 835699307 25,737 203,615 SH   DFND 0 0 203,615 0
SOTERA HEALTH CO COM 83601L102 15,770 669,660 SH   DFND 0 0 669,660 0
SOUTH JERSEY INDS INC COM 838518108 5,438 208,200 SH   DFND 0 0 208,200 0
SOUTHWEST AIRLS CO COM 844741108 7,722 180,243 SH   DFND 0 0 180,243 0
SOUTHWEST AIRLS CO NOTE 1.250% 5/0 844741BG2 16,692 12,500,000 PRN   DFND 0 0 12,500,000 0
SOUTHWEST GAS HLDGS INC COM 844895102 4,904 70,000 SH   DFND 0 0 70,000 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 1,551,932 3,267,500 SH Put DFND 0 0 3,267,500 0
SPDR SER TR PORTFOLIO INTRMD 78464A375 30,397 840,860 SH   DFND 0 0 840,860 0
SPDR SER TR S&P BIOTECH 78464A870 4,478 40,000 SH   DFND 0 0 40,000 0
SPDR SER TR S&P BIOTECH 78464A870 247,432 2,210,000 SH Call DFND 0 0 2,210,000 0
SPDR SER TR S&P HOMEBUILD 78464A888 1,287 15,000 SH   DFND 0 0 15,000 0
SPIRE INC COM 84857L101 7,116 109,100 SH   DFND 0 0 109,100 0
SPIRIT AEROSYSTEMS HLDGS INC COM CL A 848574109 62,941 1,460,698 SH   DFND 0 0 1,460,698 0
SPIRIT AIRLS INC COM 848577102 6,555 300,000 SH Call DFND 0 0 300,000 0
SPLUNK INC COM 848637104 55,615 480,600 SH   DFND 0 0 480,600 0
SPORTS ENTERTAINMENT ACQU CO *W EXP 10/30/202 84918M114 325 125,000 SH   DFND 0 0 125,000 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 181,575 775,862 SH   DFND 0 0 775,862 0
SS&C TECHNOLOGIES HLDGS INC COM 78467J100 18,685 227,927 SH   DFND 0 0 227,927 0
SSR MNG INC NOTE 2.500% 4/0 784730AB9 4,908 4,000,000 PRN   DFND 0 0 4,000,000 0
STAG INDL INC COM 85254J102 15,645 326,200 SH   DFND 0 0 326,200 0
STANDARD LITHIUM LTD COM 853606101 21 2,100 SH   DFND 0 0 2,100 0
STANLEY BLACK & DECKER INC COM 854502101 26,497 140,480 SH   DFND 0 0 140,480 0
STAR BULK CARRIERS CORP. SHS PAR Y8162K204 5,173 228,200 SH   DFND 0 0 228,200 0
STATE STR CORP COM 857477103 9,137 98,248 SH   DFND 0 0 98,248 0
STEM INC COM 85859N102 16,580 874,000 SH   DFND 0 0 874,000 0
STIFEL FINL CORP COM 860630102 26,569 377,300 SH   DFND 0 0 377,300 0
STOKE THERAPEUTICS INC COM 86150R107 5,614 233,997 SH   DFND 0 0 233,997 0
STONECO LTD COM CL A G85158106 31,678 1,878,900 SH   DFND 0 0 1,878,900 0
SUMO LOGIC INC COM 86646P103 176 13,000 SH   DFND 0 0 13,000 0
SUNCOR ENERGY INC NEW COM 867224107 145,731 5,821,706 SH   DFND 0 0 5,821,706 0
SUNLIGHT FINANCIAL HOLDINGS COM 86738J106 6,217 1,300,656 SH   DFND 0 0 1,300,656 0
SUNNOVA ENERGY INTL INC. COM 86745K104 29,731 1,064,848 SH   DFND 0 0 1,064,848 0
SUNRUN INC COM 86771W105 21,639 630,871 SH   DFND 0 0 630,871 0
SUNRUN INC COM 86771W105 6,003 175,000 SH Call DFND 0 0 175,000 0
SUNSTONE HOTEL INVS INC NEW COM 867892101 2 200 SH   DFND 0 0 200 0
SUPERNOVA PARTNERS ACQUISTN *W EXP 99/99/999 G8T86C121 148 62,500 SH   DFND 0 0 62,500 0
SUPERNOVA PARTNERS ACQUISTN SHS CL A G8T86C105 2,234 217,127 SH   DFND 0 0 217,127 0
SURGERY PARTNERS INC COM 86881A100 13,009 243,561 SH   DFND 0 0 243,561 0
SURMODICS INC COM 868873100 1,098 22,799 SH   DFND 0 0 22,799 0
SVB FINANCIAL GROUP COM 78486Q101 68,070 100,362 SH   DFND 0 0 100,362 0
SWITCH INC CL A 87105L104 6,103 213,100 SH   DFND 0 0 213,100 0
SYLVAMO CORP COMMON STOCK 871332102 2,303 82,560 SH   DFND 0 0 82,560 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 7,729 353,100 SH   DFND 0 0 353,100 0
SYNEOS HEALTH INC CL A 87166B102 81,659 795,279 SH   DFND 0 0 795,279 0
T-MOBILE US INC COM 872590104 106,908 921,783 SH   DFND 0 0 921,783 0
T-MOBILE US INC COM 872590104 11,598 100,000 SH Call DFND 0 0 100,000 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 121,970 1,013,800 SH   DFND 0 0 1,013,800 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 13,141 73,943 SH   DFND 0 0 73,943 0
TAL EDUCATION GROUP SPONSORED ADS 874080104 0 100 SH   DFND 0 0 100 0
TALKSPACE INC *W EXP 06/21/202 87427V111 290 1,250,000 SH   DFND 0 0 1,250,000 0
TALOS ENERGY INC COM 87484T108 4,851 495,000 SH   DFND 0 0 495,000 0
TANDEM DIABETES CARE INC COM NEW 875372203 20,270 134,669 SH   DFND 0 0 134,669 0
TAPESTRY INC COM 876030107 7,066 174,038 SH   DFND 0 0 174,038 0
TARGA RES CORP COM 87612G101 70,177 1,343,363 SH   DFND 0 0 1,343,363 0
TASKUS INC CLASS A COM 87652V109 6,708 124,307 SH   DFND 0 0 124,307 0
TCR2 THERAPEUTICS INC COM 87808K106 1,631 350,000 SH   DFND 0 0 350,000 0
TECK RESOURCES LTD CL B 878742204 6,989 242,500 SH   DFND 0 0 242,500 0
TELEDYNE TECHNOLOGIES INC COM 879360105 52,667 120,549 SH   DFND 0 0 120,549 0
TENABLE HLDGS INC COM 88025T102 56,777 1,031,000 SH   DFND 0 0 1,031,000 0
TENARIS S A SPONSORED ADS 88031M109 30,398 1,457,228 SH   DFND 0 0 1,457,228 0
TENET HEALTHCARE CORP COM NEW 88033G407 8,234 100,800 SH   DFND 0 0 100,800 0
TERADYNE INC COM 880770102 75,682 462,800 SH   DFND 0 0 462,800 0
TEREX CORP NEW COM 880779103 3,443 78,330 SH   DFND 0 0 78,330 0
TEXAS ROADHOUSE INC COM 882681109 19,234 215,429 SH   DFND 0 0 215,429 0
TEXTRON INC COM 883203101 6,539 84,700 SH   DFND 0 0 84,700 0
THERAVANCE BIOPHARMA INC COM G8807B106 1,603 145,100 SH   DFND 0 0 145,100 0
THERMO FISHER SCIENTIFIC INC COM 883556102 66,603 99,818 SH   DFND 0 0 99,818 0
TIMKEN CO COM 887389104 4,435 64,008 SH   DFND 0 0 64,008 0
TIPTREE INC COM 88822Q103 3,105 224,521 SH   DFND 0 0 224,521 0
TMC THE METALS COMPANY INC COM 87261Y106 548 263,400 SH   DFND 0 0 263,400 0
TPI COMPOSITES INC COM 87266J104 782 52,300 SH   DFND 0 0 52,300 0
TRANSALTA CORP COM 89346D107 5,444 489,800 SH   DFND 0 0 489,800 0
TRANSDIGM GROUP INC COM 893641100 28,750 45,185 SH   DFND 0 0 45,185 0
TRANSUNION COM 89400J107 10,981 92,600 SH   DFND 0 0 92,600 0
TREACE MED CONCEPTS INC COM 89455T109 640 34,350 SH   DFND 0 0 34,350 0
TREAN INS GROUP INC COM 89457R101 61 6,900 SH   DFND 0 0 6,900 0
TRICIDA INC COM 89610F101 31,340 3,278,236 SH   DFND 0 0 3,278,236 0
TRICIDA INC NOTE 3.500% 5/1 89610FAB7 2,770 5,000,000 PRN   DFND 0 0 5,000,000 0
TRIP COM GROUP LTD ADS 89677Q107 4,089 166,100 SH   DFND 0 0 166,100 0
TRIPADVISOR INC COM 896945201 20,960 768,900 SH   DFND 0 0 768,900 0
TRIUMPH GROUP INC NEW COM 896818101 652 35,200 SH   DFND 0 0 35,200 0
TRONOX HOLDINGS PLC SHS G9087Q102 9,612 400,000 SH   DFND 0 0 400,000 0
TUSIMPLE HLDGS INC CL A 90089L108 18,441 514,400 SH   DFND 0 0 514,400 0
TYLER TECHNOLOGIES INC COM 902252105 22,164 41,200 SH   DFND 0 0 41,200 0
TYSON FOODS INC CL A 902494103 3,722 42,700 SH   DFND 0 0 42,700 0
UBER TECHNOLOGIES INC COM 90353T100 195,914 4,672,418 SH   DFND 0 0 4,672,418 0
UBER TECHNOLOGIES INC COM 90353T100 35,305 842,000 SH Call DFND 0 0 842,000 0
UDEMY INC COM 902685106 946 48,400 SH   DFND 0 0 48,400 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 35,812 425,874 SH   DFND 0 0 425,874 0
UNDER ARMOUR INC CL A 904311107 69,949 3,301,026 SH   DFND 0 0 3,301,026 0
UNDER ARMOUR INC CL A 904311107 4,238 200,000 SH Call DFND 0 0 200,000 0
UNDER ARMOUR INC CL C 904311206 7,736 428,800 SH   DFND 0 0 428,800 0
UNIQURE NV SHS N90064101 40,765 1,965,520 SH   DFND 0 0 1,965,520 0
UNITED FIRE GROUP INC COM 910340108 306 13,200 SH   DFND 0 0 13,200 0
UNITED PARCEL SERVICE INC CL B 911312106 3,410 15,907 SH   DFND 0 0 15,907 0
UNITED RENTALS INC COM 911363109 30,433 91,587 SH   DFND 0 0 91,587 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 44,772 207,200 SH   DFND 0 0 207,200 0
UNITEDHEALTH GROUP INC COM 91324P102 4,118 8,200 SH   DFND 0 0 8,200 0
UNITI GROUP INC COM 91325V108 1,007 71,901 SH   DFND 0 0 71,901 0
UNIVERSAL DISPLAY CORP COM 91347P105 10,187 61,727 SH   DFND 0 0 61,727 0
USHG ACQUISITION CORP *W EXP 02/24/202 91748P118 194 116,666 SH   DFND 0 0 116,666 0
USHG ACQUISITION CORP COM CL A 91748P100 3,630 350,000 SH   DFND 0 0 350,000 0
VACCINEX INC COM 918640103 411 395,522 SH   DFND 0 0 395,522 0
VAIL RESORTS INC COM 91879Q109 7,869 23,997 SH   DFND 0 0 23,997 0
VALVOLINE INC COM 92047W101 33,020 885,500 SH   DFND 0 0 885,500 0
VANECK ETF TRUST VANECK RUSSIA ET 92189F403 267 10,000 SH   DFND 0 0 10,000 0
VANGUARD INTL EQUITY INDEX F FTSE EUROPE ETF 922042874 7,848 115,000 SH   DFND 0 0 115,000 0
VANGUARD SCOTTSDALE FDS SHRT TRM CORP BD 92206C409 15,008 184,690 SH   DFND 0 0 184,690 0
VANGUARD WORLD FDS INDUSTRIAL ETF 92204A603 5,074 25,000 SH   DFND 0 0 25,000 0
VEECO INSTRS INC DEL COM 922417100 2,596 91,200 SH   DFND 0 0 91,200 0
VERISIGN INC COM 92343E102 31,990 126,034 SH   DFND 0 0 126,034 0
VERTEX PHARMACEUTICALS INC COM 92532F100 10,453 47,600 SH   DFND 0 0 47,600 0
VIATRIS INC COM 92556V106 13,066 965,700 SH Call DFND 0 0 965,700 0
VICTORIAS SECRET AND CO COMMON STOCK 926400102 27,238 490,415 SH   DFND 0 0 490,415 0
VIEWRAY INC COM 92672L107 14,978 2,718,379 SH   DFND 0 0 2,718,379 0
VINCERX PHARMA INC COM NEW 92731L106 3,514 344,827 SH   DFND 0 0 344,827 0
VIR BIOTECHNOLOGY INC COM 92764N102 86,047 2,055,100 SH   DFND 0 0 2,055,100 0
VIRGIN GALACTIC HOLDINGS INC COM 92766K106 4,884 365,000 SH   DFND 0 0 365,000 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 9,349 472,864 SH   DFND 0 0 472,864 0
VISA INC COM CL A 92826C839 50,745 234,163 SH   DFND 0 0 234,163 0
VISTRA CORP COM 92840M102 57,080 2,506,800 SH   DFND 0 0 2,506,800 0
VNET GROUP INC SPONSORED ADS A 90138A103 1,429 158,300 SH   DFND 0 0 158,300 0
VOCERA COMMUNICATIONS INC COM 92857F107 9,460 145,900 SH   DFND 0 0 145,900 0
VULCAN MATLS CO COM 929160109 30,660 147,703 SH   DFND 0 0 147,703 0
WALGREENS BOOTS ALLIANCE INC COM 931427108 87,174 1,671,284 SH   DFND 0 0 1,671,284 0
WALGREENS BOOTS ALLIANCE INC COM 931427108 39,120 750,000 SH Call DFND 0 0 750,000 0
WALMART INC COM 931142103 104,709 723,676 SH   DFND 0 0 723,676 0
WARNER MUSIC GROUP CORP COM CL A 934550203 61,225 1,417,898 SH   DFND 0 0 1,417,898 0
WARRIOR MET COAL INC COM 93627C101 460 17,900 SH   DFND 0 0 17,900 0
WATSCO INC COM 942622200 5,111 16,335 SH   DFND 0 0 16,335 0
WELLS FARGO CO NEW COM 949746101 4,841 100,900 SH   DFND 0 0 100,900 0
WENDYS CO COM 95058W100 14,498 607,899 SH   DFND 0 0 607,899 0
WESTERN ALLIANCE BANCORP COM 957638109 38,377 356,500 SH   DFND 0 0 356,500 0
WESTERN DIGITAL CORP. COM 958102105 121,234 1,859,137 SH   DFND 0 0 1,859,137 0
WESTLAKE CHEM CORP COM 960413102 2,292 23,595 SH   DFND 0 0 23,595 0
WESTROCK CO COM 96145D105 887 20,000 SH   DFND 0 0 20,000 0
WILLIS TOWERS WATSON PLC LTD SHS G96629103 20,026 84,325 SH   DFND 0 0 84,325 0
WOLFSPEED INC COM 977852102 2,235 20,000 SH Put DFND 0 0 20,000 0
WOLFSPEED INC NOTE 1.750% 5/0 225447AD3 32,281 13,150,000 PRN   DFND 0 0 13,150,000 0
WOODWARD INC COM 980745103 11,668 106,600 SH   DFND 0 0 106,600 0
WYNN RESORTS LTD COM 983134107 5,528 65,000 SH Call DFND 0 0 65,000 0
X4 PHARMACEUTICALS INC COM 98420X103 3,740 1,633,204 SH   DFND 0 0 1,633,204 0
XCEL ENERGY INC COM 98389B100 64,787 956,979 SH   DFND 0 0 956,979 0
XENCOR INC COM 98401F105 26,781 667,517 SH   DFND 0 0 667,517 0
XENON PHARMACEUTICALS INC COM 98420N105 93,489 2,992,597 SH   DFND 0 0 2,992,597 0
XEROX HOLDINGS CORP COM NEW 98421M106 12,307 543,592 SH   DFND 0 0 543,592 0
XPENG INC ADS 98422D105 37,526 745,600 SH   DFND 0 0 745,600 0
XPO LOGISTICS INC COM 983793100 38,882 502,160 SH   DFND 0 0 502,160 0
YELP INC CL A 985817105 19,262 531,515 SH   DFND 0 0 531,515 0
YETI HLDGS INC COM 98585X104 7,565 91,328 SH   DFND 0 0 91,328 0
YPF SOCIEDAD ANONIMA SPON ADR CL D 984245100 285 74,700 SH   DFND 0 0 74,700 0
ZAI LAB LTD ADR 98887Q104 7,492 119,200 SH   DFND 0 0 119,200 0
ZENDESK INC COM 98936J101 96,802 928,200 SH   DFND 0 0 928,200 0
ZILLOW GROUP INC CL A 98954M101 1,244 20,000 SH   DFND 0 0 20,000 0
ZILLOW GROUP INC CL C CAP STK 98954M200 20,092 314,675 SH   DFND 0 0 314,675 0
ZILLOW GROUP INC CL C CAP STK 98954M200 5,747 90,000 SH Call DFND 0 0 90,000 0
ZIM INTEGRATED SHIPPING SERV SHS M9T951109 8,476 144,000 SH   DFND 0 0 144,000 0
ZIOPHARM ONCOLOGY INC COM 98973P101 1,090 1,000,000 SH   DFND 0 0 1,000,000 0
ZOETIS INC CL A 98978V103 35,029 143,544 SH   DFND 0 0 143,544 0
ZOOMINFO TECHNOLOGIES INC COM CL A 98980F104 35,926 559,600 SH   DFND 0 0 559,600 0
ZSCALER INC COM 98980G102 4,622 14,384 SH   DFND 0 0 14,384 0
ZTO EXPRESS CAYMAN INC SPONSORED ADS A 98980A105 127 4,500 SH   DFND 0 0 4,500 0
ZUMIEZ INC COM 989817101 1,046 21,800 SH   DFND 0 0 21,800 0
ZYMEWORKS INC COM 98985W102 12,301 750,500 SH   DFND 0 0 750,500 0
ZYNGA INC CL A 98986T108 81,435 12,724,200 SH   DFND 0 0 12,724,200 0