The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Aerojet Rocketdyne Holdings In Common Stock 007800105 5,254 120,651 SH   SOLE   120,651 0 0
AeroVironment Inc Common Stock 008073108 75,474 874,349 SH   SOLE   874,349 0 0
Align Technology Inc Common Stock 016255101 6,321 9,499 SH   SOLE   9,499 0 0
Allegheny Technologies Inc Common Stock 01741R102 421 25,342 SH   SOLE   25,342 0 0
Alphabet Inc Common Stock 02079K107 71,585 26,858 SH   SOLE   26,858 0 0
Altair Engineering Inc Common Stock 021369103 18,316 265,682 SH   SOLE   265,682 0 0
Amazon.com Inc Common Stock 023135106 43,737 13,314 SH   SOLE   13,314 0 0
AMETEK Inc Common Stock 031100100 5,544 44,705 SH   SOLE   44,705 0 0
ANSYS Inc Common Stock 03662Q105 48,081 141,229 SH   SOLE   141,229 0 0
AquaBounty Technologies Inc Common Stock 03842K200 25,221 6,196,878 SH   SOLE   6,196,878 0 0
Arcturus Therapeutics Holdings Common Stock 03969T109 120,860 2,529,509 SH   SOLE   2,529,509 0 0
Autodesk Inc Common Stock 052769106 17,339 60,801 SH   SOLE   60,801 0 0
Baidu Inc ADR 056752108 36,117 234,905 SH   SOLE   234,905 0 0
Renishaw PLC Common Stock G75006117 17,138 268,144 SH   SOLE   268,144 0 0
CareDx Inc Common Stock 14167L103 216,101 3,410,153 SH   SOLE   3,410,153 0 0
Carpenter Technology Corp Common Stock 144285103 454 13,876 SH   SOLE   13,876 0 0
Castle Biosciences Inc Common Stock 14843C105 136,848 2,057,867 SH   SOLE   2,057,867 0 0
Cellectis SA ADR 15117K103 47,701 3,782,763 SH   SOLE   3,782,763 0 0
Cerus Corp Common Stock 157085101 104,052 17,085,744 SH   SOLE   15,614,299 579,822 891,623
Codexis Inc Common Stock 192005106 135,687 5,833,501 SH   SOLE   5,833,501 0 0
Deere & Co Common Stock 244199105 89,069 265,823 SH   SOLE   265,823 0 0
DuPont de Nemours Inc Common Stock 26614N102 454 6,677 SH   SOLE   6,677 0 0
Eastman Chemical Co Common Stock 277432100 471 4,680 SH   SOLE   4,680 0 0
Editas Medicine Inc Common Stock 28106W103 258,696 6,297,359 SH   SOLE   5,351,738 750,701 194,920
ExOne Co/The Common Stock 302104104 26,311 1,125,369 SH   SOLE   1,079,022 0 46,347
Meta Platforms Inc Common Stock 30303M102 71,300 210,084 SH   SOLE   210,084 0 0
FARO Technologies Inc Common Stock 311642102 5,219 79,300 SH   SOLE   79,300 0 0
Fate Therapeutics Inc Common Stock 31189P102 646,177 10,902,258 SH   SOLE   10,898,564 0 3,694
Grayscale Bitcoin Trust BTC Open-End Fund 389637109 298,558 8,820,036 SH   SOLE   8,100,295 703,852 15,889
Guardant Health Inc Common Stock 40131M109 12 93 SH   SOLE   93 0 0
HP Inc Common Stock 40434L105 17,763 649,216 SH   SOLE   649,216 0 0
Hexcel Corp Common Stock 428291108 541 9,112 SH   SOLE   9,112 0 0
Incyte Corp Common Stock 45337C102 197,560 2,872,346 SH   SOLE   2,872,346 0 0
Intellia Therapeutics Inc Common Stock 45826J105 904,648 6,743,556 SH   SOLE   5,697,670 777,794 268,092
Intercontinental Exchange Inc Common Stock 45866F104 57,307 499,099 SH   SOLE   499,099 0 0
Intuit Inc Common Stock 461202103 66,071 122,464 SH   SOLE   122,464 0 0
Intuitive Surgical Inc Common Stock 46120E602 8,277 24,978 SH   SOLE   24,978 0 0
OC Oerlikon Corp AG Common Stock H59187106 5,491 500,857 SH   SOLE   500,857 0 0
Invitae Corp Common Stock 46185L103 736,845 25,917,886 SH   SOLE   21,979,170 2,976,494 962,222
Ionis Pharmaceuticals Inc Common Stock 462222100 285,472 8,511,384 SH   SOLE   8,511,384 0 0
Iovance Biotherapeutics Inc Common Stock 462260100 287,285 11,649,837 SH   SOLE   11,214,110 257,426 178,301
Iridium Communications Inc Common Stock 46269C102 477,112 11,972,702 SH   SOLE   10,988,905 791,043 192,754
JD.com Inc ADR 47215P106 173,350 2,399,639 SH   SOLE   2,399,639 0 0
SGL Carbon SE Common Stock D6949M108 521 48,124 SH   SOLE   48,124 0 0
Kaiser Aluminum Corp Common Stock 483007704 5,275 48,413 SH   SOLE   48,413 0 0
Komatsu Ltd ADR 500458401 93,300 3,887,491 SH   SOLE   3,887,491 0 0
Kratos Defense & Security Solu Common Stock 50077B207 213,372 9,563,962 SH   SOLE   9,563,962 0 0
Henkel AG & Co KGaA Preference D3207M110 479 5,157 SH   SOLE   5,157 0 0
LendingClub Corp Common Stock 52603A208 81,565 2,888,278 SH   SOLE   2,231,238 73,187 583,853
Lincoln Electric Holdings Inc Common Stock 533900106 5,405 41,964 SH   SOLE   41,964 0 0
Siemens AG Common Stock D69671218 5,887 35,776 SH   SOLE   35,776 0 0
Materialise NV ADR 57667T100 112,448 5,594,437 SH   SOLE   5,342,700 75,126 176,611
MercadoLibre Inc Common Stock 58733R102 159,085 94,727 SH   SOLE   94,727 0 0
Microsoft Corp Common Stock 594918104 17,760 62,998 SH   SOLE   62,998 0 0
Bezeq The Israeli Telecommunic Common Stock M2012Q100 4,112 3,484,601 SH   SOLE   3,484,601 0 0
Moog Inc Common Stock 615394202 5,372 70,472 SH   SOLE   70,472 0 0
Danel Adir Yeoshua Ltd Common Stock M27013107 3,385 17,342 SH   SOLE   17,342 0 0
Hilan Ltd Common Stock M5299H123 3,870 68,640 SH   SOLE   68,640 0 0
Nano Dimension Ltd ADR 63008G203 106,737 18,925,002 SH   SOLE   18,925,002 0 0
NanoString Technologies Inc Common Stock 63009R109 75,161 1,565,538 SH   SOLE   1,493,301 72,237 0
Elbit Systems Ltd Common Stock M3760D101 46,674 322,242 SH   SOLE   322,242 0 0
Partner Communications Co Ltd Common Stock M78465107 3,906 841,116 SH   SOLE   841,116 0 0
Netflix Inc Common Stock 64110L106 15,488 25,376 SH   SOLE   25,376 0 0
Nice Ltd ADR 653656108 3,953 13,917 SH   SOLE   13,917 0 0
NVIDIA Corp Common Stock 67066G104 1,619 7,817 SH   SOLE   7,817 0 0
Matrix IT Ltd Common Stock M6859E153 3,730 139,976 SH   SOLE   139,976 0 0
Toray Industries Inc Common Stock J89494116 531 82,699 SH   SOLE   82,699 0 0
PTC Inc Common Stock 69370C100 15,179 126,717 SH   SOLE   126,717 0 0
Pacific Biosciences of Califor Common Stock 69404D108 580,575 22,723,075 SH   SOLE   21,931,123 465,210 326,742
One Software Technologies Ltd Common Stock M75260113 3,843 238,131 SH   SOLE   238,131 0 0
PayPal Holdings Inc Common Stock 70450Y103 198,282 762,007 SH   SOLE   762,007 0 0
Personalis Inc Common Stock 71535D106 99,382 5,165,360 SH   SOLE   5,165,360 0 0
Straumann Holding AG Common Stock H8300N119 19,070 10,581 SH   SOLE   10,581 0 0
Pinduoduo Inc ADR 722304102 59,567 656,969 SH   SOLE   656,969 0 0
Pinterest Inc Common Stock 72352L106 81,711 1,603,748 SH   SOLE   1,603,748 0 0
Pluristem Therapeutics Inc Common Stock 72940R300 2,452 925,361 SH   SOLE   925,361 0 0
Proto Labs Inc Common Stock 743713109 174,447 2,619,323 SH   SOLE   2,144,375 345,499 129,449
Redhill Biopharma Ltd ADR 757468103 88 19,132 SH   SOLE   19,132 0 0
Roku Inc Common Stock 77543R102 1,484,571 4,737,742 SH   SOLE   4,216,708 403,922 117,112
Shopify Inc Common Stock 82509L107 1,250,853 922,608 SH   SOLE   843,618 62,687 16,303
Snap Inc Common Stock 83304A106 71,995 974,621 SH   SOLE   974,621 0 0
Splunk Inc Common Stock 848637104 81,583 563,772 SH   SOLE   563,772 0 0
Square Inc Common Stock 852234103 1,467,937 6,120,486 SH   SOLE   5,580,478 418,332 121,676
Taiwan Semiconductor Manufactu ADR 874039100 1 10 SH   SOLE   10 0 0
Teladoc Health Inc Common Stock 87918A105 2,087,269 16,459,812 SH   SOLE   15,224,523 951,444 283,845
Tencent Holdings Ltd ADR 88032Q109 43,698 731,096 SH   SOLE   731,096 0 0
Teradyne Inc Common Stock 880770102 61,335 561,829 SH   SOLE   561,829 0 0
Tesla Inc Common Stock 88160R101 3,064,923 3,952,292 SH   SOLE   3,637,798 311,606 2,888
Teva Pharmaceutical Industries ADR 881624209 3,935 403,996 SH   SOLE   403,996 0 0
3D Systems Corp Common Stock 88554D205 110,615 4,012,169 SH   SOLE   4,012,169 0 0
3M Co Common Stock 88579Y101 459 2,617 SH   SOLE   2,617 0 0
Trimble Inc Common Stock 896239100 364,634 4,433,239 SH   SOLE   4,316,477 71,032 45,730
Twilio Inc Common Stock 90138F102 1,036,458 3,248,577 SH   SOLE   2,936,735 246,075 65,767
Twist Bioscience Corp Common Stock 90184D100 422,147 3,946,409 SH   SOLE   3,786,400 79,681 80,328
2U Inc Common Stock 90214J101 282,400 8,412,272 SH   SOLE   7,103,201 902,690 406,381
United Parcel Service Inc Common Stock 911312106 4,863 26,706 SH   SOLE   26,706 0 0
Veracyte Inc Common Stock 92337F107 324,230 6,980,201 SH   SOLE   6,806,346 173,855 0
Workday Inc Common Stock 98138H101 61,249 245,102 SH   SOLE   245,102 0 0
Xerox Holdings Corp Common Stock 98421M106 453 22,473 SH   SOLE   22,473 0 0
Zillow Group Inc Common Stock 98954M200 994,827 11,286,900 SH   SOLE   10,248,274 806,359 232,267
Koninklijke DSM NV Common Stock N5017D122 557 2,789 SH   SOLE   2,789 0 0
Arkema SA Common Stock F0392W125 556 4,199 SH   SOLE   4,199 0 0
Sandvik AB Common Stock W74857165 454 19,778 SH   SOLE   19,778 0 0
Cellcom Israel Ltd Common Stock M2196U109 3,296 945,639 SH   SOLE   945,639 0 0
Evonik Industries AG Common Stock D2R90Y117 488 15,500 SH   SOLE   15,500 0 0
Fattal Holdings 1998 Ltd Common Stock M4148G105 3,356 37,250 SH   SOLE   37,250 0 0
SLM Solutions Group AG Common Stock D6T690109 19,148 899,359 SH   SOLE   899,359 0 0
Adyen NV Common Stock N3501V104 114,199 40,867 SH   SOLE   40,867 0 0
Sapiens International Corp NV Common Stock G7T16G103 4,035 140,213 SH   SOLE   140,213 0 0
CRISPR Therapeutics AG Common Stock H17182108 849,064 7,585,674 SH   SOLE   6,786,246 609,964 189,464
Spotify Technology SA Common Stock L8681T102 1,039,743 4,614,109 SH   SOLE   4,132,506 363,152 118,451
Allot Ltd Common Stock M0854Q105 2,894 194,765 SH   SOLE   194,765 0 0
AudioCodes Ltd Common Stock M15342104 3,613 111,047 SH   SOLE   111,047 0 0
Camtek Ltd/Israel Common Stock M20791105 4,196 103,588 SH   SOLE   103,588 0 0
Ceragon Networks Ltd Common Stock M22013102 3,591 1,028,812 SH   SOLE   1,028,812 0 0
Check Point Software Technolog Common Stock M22465104 3,244 28,702 SH   SOLE   28,702 0 0
Compugen Ltd Common Stock M25722105 58,701 9,832,678 SH   SOLE   9,480,616 219,844 132,218
CyberArk Software Ltd Common Stock M2682V108 4,136 26,205 SH   SOLE   26,205 0 0
Evogene Ltd Common Stock M4119S104 7,726 2,926,562 SH   SOLE   2,926,562 0 0
Evogene Ltd Common Stock M4119S104 2,927 1,102,627 SH   SOLE   1,102,627 0 0
Fiverr International Ltd Common Stock M4R82T106 3,085 16,888 SH   SOLE   16,888 0 0
Ituran Location and Control Lt Common Stock M6158M104 3,670 144,561 SH   SOLE   144,561 0 0
Nova Ltd Common Stock M7516K103 3,858 37,720 SH   SOLE   37,720 0 0
Radware Ltd Common Stock M81873107 3,906 115,827 SH   SOLE   115,827 0 0
Stratasys Ltd Common Stock M85548101 155,581 7,229,607 SH   SOLE   5,500,449 1,101,824 627,334
Taro Pharmaceutical Industries Common Stock M8737E108 3,256 51,167 SH   SOLE   51,167 0 0
Tower Semiconductor Ltd Common Stock M87915274 3,994 133,576 SH   SOLE   133,576 0 0
UroGen Pharma Ltd Common Stock M96088105 4,107 244,165 SH   SOLE   244,165 0 0
Wix.com Ltd Common Stock M98068105 2,425 12,374 SH   SOLE   12,374 0 0
NXP Semiconductors NV Common Stock N6596X109 463 2,366 SH   SOLE   2,366 0 0
DocuSign Inc Common Stock 256163106 468,905 1,821,484 SH   SOLE   1,727,727 61,671 32,086
Discovery Ltd Common Stock S2192Y109 60,490 6,678,658 SH   SOLE   6,678,658 0 0
Inmode Ltd Common Stock M5425M103 5,509 69,100 SH   SOLE   69,100 0 0
Perion Network Ltd Common Stock M78673114 3,411 196,809 SH   SOLE   196,809 0 0
Silvergate Capital Corp Common Stock 82837P408 71,571 619,661 SH   SOLE   619,661 0 0
Z Holdings Corp Common Stock J9894K105 71,089 11,038,176 SH   SOLE   11,038,176 0 0
Sea Ltd ADR 81141R100 303,839 953,280 SH   SOLE   897,910 42,706 12,664
Z Holdings Corp ADR 98877X101 157 12,232 SH   SOLE   12,232 0 0
Pure Storage Inc Common Stock 74624M102 0 0 SH   SOLE   0 0 0
Synopsys Inc Common Stock 871607107 31,800 106,208 SH   SOLE   106,208 0 0
RADA Electronic Industries Ltd Common Stock M81863124 3,145 295,623 SH   SOLE   295,623 0 0
PagerDuty Inc Common Stock 69553P100 414,074 9,996,968 SH   SOLE   8,647,717 1,028,321 320,930
Caterpillar Inc Common Stock 149123101 41,824 217,865 SH   SOLE   217,865 0 0
Arconic Corp Common Stock 03966V107 5,305 168,202 SH   SOLE   168,202 0 0
Adaptive Biotechnologies Corp Common Stock 00650F109 165,070 4,856,421 SH   SOLE   4,856,421 0 0
10X Genomics Inc Common Stock 88025U109 451,582 3,101,951 SH   SOLE   2,755,113 277,104 69,734
Bitcoin Fund/The Closed-End Fund 09175G104 11,701 258,536 SH   SOLE   0 0 258,536
Schrodinger Inc/United States Common Stock 80810D103 124,882 2,283,876 SH   SOLE   2,283,876 0 0
TCS Group Holding PLC GDR 87238U203 68,091 741,733 SH   SOLE   741,733 0 0
Adyen NV ADR 00783V104 44,245 1,577,916 SH   SOLE   1,577,916 0 0
Cie Generale des Etablissement Common Stock F61824144 5,373 34,963 SH   SOLE   34,963 0 0
voestalpine AG Common Stock A9101Y103 468 12,615 SH   SOLE   12,615 0 0
Yeahka Ltd Common Stock G9835C108 189 58,400 SH   SOLE   58,400 0 0
Accolade Inc Common Stock 00437E102 220,612 5,231,496 SH   SOLE   5,231,496 0 0
Berkeley Lights Inc Common Stock 084310101 166,317 8,502,916 SH   SOLE   8,502,916 0 0
Vertex Pharmaceuticals Inc Common Stock 92532F100 310,132 1,709,751 SH   SOLE   1,709,751 0 0
BYD Co Ltd ADR 05606L100 21,614 346,606 SH   SOLE   346,606 0 0
Kamada Ltd Common Stock M6240T109 3,432 647,538 SH   SOLE   647,538 0 0
BATM Advanced Communications L Common Stock M19199112 3,666 3,064,234 SH   SOLE   3,064,234 0 0
Gamida Cell Ltd Common Stock M47364100 2,445 623,674 SH   SOLE   623,674 0 0
Gilat Satellite Networks Ltd Common Stock M51474118 3,455 384,275 SH   SOLE   384,275 0 0
PolyPid Ltd Common Stock M8001Q118 3,668 471,414 SH   SOLE   471,414 0 0
Silicom Ltd Common Stock M84116108 3,749 86,684 SH   SOLE   86,684 0 0
Nintendo Co Ltd ADR 654445303 6,951 117,316 SH   SOLE   117,316 0 0
Organovo Holdings Inc Common Stock 68620A203 2,595 381,586 SH   SOLE   378,058 3,528 0
Surface Oncology Inc Common Stock 86877M209 34,961 4,618,354 SH   SOLE   4,618,354 0 0
Takeda Pharmaceutical Co Ltd ADR 874060205 221,157 13,501,650 SH   SOLE   13,501,650 0 0
Niu Technologies ADR 65481N100 56,417 2,434,920 SH   SOLE   2,434,920 0 0
Thermo Fisher Scientific Inc Common Stock 883556102 571 999 SH   SOLE   999 0 0
Exact Sciences Corp Common Stock 30063P105 1,119,498 11,728,629 SH   SOLE   10,657,628 847,593 223,408
Snowflake Inc Common Stock 833445109 30 98 SH   SOLE   98 0 0
Unity Software Inc Common Stock 91332U101 1,503,460 11,908,598 SH   SOLE   10,839,031 815,158 254,409
Beam Therapeutics Inc Common Stock 07373V105 595,298 6,841,722 SH   SOLE   6,841,722 0 0
Novartis AG Common Stock H5820Q150 298 3,621 SH   SOLE   3,621 0 0
Regeneron Pharmaceuticals Inc Common Stock 75886F107 259,106 428,147 SH   SOLE   428,147 0 0
Repare Therapeutics Inc Common Stock 760273102 77,847 2,966,739 SH   SOLE   2,966,739 0 0
Cloudflare Inc Common Stock 18915M107 52,567 466,636 SH   SOLE   466,636 0 0
Palantir Technologies Inc Common Stock 69608A108 895,304 37,242,249 SH   SOLE   33,960,779 2,529,536 751,934
Zoom Video Communications Inc Common Stock 98980L101 1,155,427 4,418,458 SH   SOLE   4,002,409 322,195 93,854
Honeywell International Inc Common Stock 438516106 6,102 28,743 SH   SOLE   28,743 0 0
Alphabet Inc Common Stock 02079K305 3 1 SH   SOLE   1 0 0
Roche Holding AG ADR 771195104 47 1,036 SH   SOLE   1,036 0 0
Opendoor Technologies Inc Common Stock 683712103 120,815 5,884,810 SH   SOLE   5,884,810 0 0
Kaspi.KZ JSC GDR 48581R205 21,759 204,890 SH   SOLE   204,890 0 0
908 Devices Inc Common Stock 65443P102 89,459 2,750,877 SH   SOLE   2,750,877 0 0
Magna International Inc Common Stock 559222401 53,119 705,999 SH   SOLE   705,999 0 0
Peloton Interactive Inc Common Stock 70614W100 149,971 1,722,817 SH   SOLE   1,722,817 0 0
Veeva Systems Inc Common Stock 922475108 212,145 736,180 SH   SOLE   736,180 0 0
Grayscale Ethereum Trust Open-End Fund 389638107 20,511 721,961 SH   SOLE   6,399 715,562 0
SPDR S&P 500 ETF Trust ETP 78462F103 6 14 SH   SOLE   14 0 0
1Life Healthcare Inc Common Stock 68269G107 72,668 3,588,540 SH   SOLE   3,588,540 0 0
PyroGenesis Canada Inc Common Stock 74734T104 473 117,215 SH   SOLE   117,215 0 0
Arad Ltd Common Stock M1492B104 4,123 281,092 SH   SOLE   281,092 0 0
Augwind Energy Tech Storage Lt Common Stock M6058P108 2,639 183,185 SH   SOLE   183,185 0 0
Bet Shemesh Engines Holdings 1 Common Stock M20119109 4,052 186,041 SH   SOLE   186,041 0 0
Electra Consumer Products 1970 Common Stock M3798N105 3,310 67,884 SH   SOLE   67,884 0 0
E&M Computing Ltd Common Stock M4026X105 3,546 604,575 SH   SOLE   604,575 0 0
Intercure Ltd Common Stock M549GJ111 1,974 287,671 SH   SOLE   287,671 0 0
Magic Software Enterprises Ltd Common Stock 559166103 4,184 211,100 SH   SOLE   211,100 0 0
Malam - Team Ltd Common Stock M87437105 3,697 113,425 SH   SOLE   113,425 0 0
Plasson Industries Ltd Common Stock M7933B108 4,895 69,361 SH   SOLE   69,361 0 0
Desktop Metal Inc Common Stock 25058X105 14,008 1,953,706 SH   SOLE   1,953,706 0 0
Enlivex Therapeutics Ltd Common Stock M4130Y106 4,523 457,797 SH   SOLE   457,797 0 0
JFrog Ltd Common Stock M6191J100 2,716 81,075 SH   SOLE   81,075 0 0
Eastman Kodak Co Common Stock 277461406 486 71,424 SH   SOLE   71,424 0 0
Kornit Digital Ltd Common Stock M6372Q113 4,440 30,678 SH   SOLE   30,678 0 0
Lockheed Martin Corp Common Stock 539830109 122,017 353,571 SH   SOLE   353,571 0 0
Nano-X Imaging Ltd Common Stock M70700105 2,781 123,613 SH   SOLE   123,613 0 0
SolarEdge Technologies Inc Common Stock 83417M104 3,896 14,688 SH   SOLE   14,688 0 0
Skillz Inc Common Stock 83067L109 184,971 18,836,108 SH   SOLE   17,912,542 574,868 348,698
Teledyne Technologies Inc Common Stock 879360105 36,101 84,037 SH   SOLE   84,037 0 0
Twitter Inc Common Stock 90184L102 832,470 13,784,899 SH   SOLE   12,481,266 1,035,688 267,945
Butterfly Network Inc Common Stock 124155102 75,072 7,190,816 SH   SOLE   7,190,816 0 0
Signify Health Inc Common Stock 82671G100 320,480 17,933,990 SH   SOLE   17,188,926 453,823 291,241
ARK Innovation ETF ETP 00214Q104 4,903 44,362 SH   SOLE   44,362 0 0
Bill.com Holdings Inc Common Stock 090043100 52,759 197,637 SH   SOLE   197,637 0 0
DraftKings Inc Common Stock 26142R104 844,489 17,535,061 SH   SOLE   15,970,469 1,231,578 333,014
Vuzix Corp Common Stock 92921W300 77,235 7,383,848 SH   SOLE   7,383,848 0 0
iShares Russell 1000 Growth ET ETP 464287614 234 853 SH   SOLE   853 0 0
Airbus SE Common Stock N0280G100 5,792 43,493 SH   SOLE   43,493 0 0
Thales SA Common Stock F9156M108 21,772 223,576 SH   SOLE   223,576 0 0
Komatsu Ltd Common Stock J35759125 24,863 1,028,088 SH   SOLE   1,028,088 0 0
Boeing Co/The Common Stock 097023105 6,660 30,281 SH   SOLE   30,281 0 0
Garmin Ltd Common Stock H2906T109 5,034 32,382 SH   SOLE   32,382 0 0
HEICO Corp Common Stock 422806109 5,594 42,423 SH   SOLE   42,423 0 0
L3Harris Technologies Inc Common Stock 502431109 30,630 139,076 SH   SOLE   139,076 0 0
The 3D Printing ETF ETP 00214Q500 40,397 1,131,579 SH   SOLE   1,131,579 0 0
ROBLOX Corp Common Stock 771049103 97,929 1,296,213 SH   SOLE   1,296,213 0 0
Spirit AeroSystems Holdings In Common Stock 848574109 9,947 225,085 SH   SOLE   225,085 0 0
UiPath Inc Common Stock 90364P105 1,259,161 23,933,868 SH   SOLE   22,391,837 1,154,159 387,872
Coinbase Global Inc Common Stock 19260Q107 1,590,805 6,993,163 SH   SOLE   6,326,501 521,424 145,238
TuSimple Holdings Inc Common Stock 90089L108 382,967 10,314,228 SH   SOLE   8,987,013 1,108,144 219,071
Recursion Pharmaceuticals Inc Common Stock 75629V104 59,684 2,593,836 SH   SOLE   2,593,836 0 0
Zymergen Inc Common Stock 98985X100 49,816 3,782,501 SH   SOLE   3,782,501 0 0
Okta Inc Common Stock 679295105 53,502 225,425 SH   SOLE   225,425 0 0
Blade Air Mobility Inc Common Stock 092667104 61,335 5,897,572 SH   SOLE   5,897,572 0 0
JD Logistics Inc Common Stock G5074S101 22,545 5,417,313 SH   SOLE   5,417,313 0 0
Hexagon AB Common Stock W4R431112 6,052 390,275 SH   SOLE   390,275 0 0
StoneCo Ltd Common Stock G85158106 63,101 1,817,433 SH   SOLE   1,817,433 0 0
Dynamics Special Purpose Corp Common Stock 268010105 23,132 2,327,123 SH   SOLE   2,327,123 0 0
Walt Disney Co/The Common Stock 254687106 66,633 393,879 SH   SOLE   393,879 0 0
Quantum-Si Inc Common Stock 74765K105 105,904 12,698,381 SH   SOLE   12,698,381 0 0
Verve Therapeutics Inc Common Stock 92539P101 59,582 1,267,705 SH   SOLE   1,267,705 0 0
Etsy Inc Common Stock 29786A106 123,776 595,192 SH   SOLE   595,192 0 0
Markforged Holding Corp Common Stock 57064N102 61,062 9,308,302 SH   SOLE   9,308,302 0 0
Dassault Systemes SE Common Stock F24571451 34,113 648,446 SH   SOLE   648,446 0 0
Conformis Inc Common Stock 20717E101 19,354 14,551,646 SH   SOLE   14,551,646 0 0
Exco Technologies Ltd Common Stock 30150P109 5,247 671,675 SH   SOLE   671,675 0 0
Xometry Inc Common Stock 98423F109 13,895 240,947 SH   SOLE   240,947 0 0
5N Plus Inc Common Stock 33833X101 521 239,337 SH   SOLE   239,337 0 0
BICO Group AB Common Stock W2R45B104 19,614 329,417 SH   SOLE   329,417 0 0
Farfetch Ltd Common Stock 30744W107 94,271 2,515,223 SH   SOLE   2,515,223 0 0
Robinhood Markets Inc Common Stock 770700102 415,616 9,876,801 SH   SOLE   8,786,936 884,447 205,418
Caribou Biosciences Inc Common Stock 142038108 117 4,903 SH   SOLE   4,903 0 0
Sema4 Holdings Corp Common Stock 81663L101 71,312 9,395,504 SH   SOLE   9,395,504 0 0
Concord Acquisition Corp Common Stock 206071102 28,219 2,799,532 SH   SOLE   2,799,532 0 0
Khosla Ventures Acquisition Co Common Stock 482505104 48,298 4,744,357 SH   SOLE   4,744,357 0 0
BioLine RX Ltd ADR 09071M205 2,953 1,073,913 SH   SOLE   1,073,913 0 0
Chemomab Therapeutics Ltd ADR 16385C104 2,000 180,523 SH   SOLE   180,523 0 0
Priortech Ltd Common Stock M8164J109 4,456 137,641 SH   SOLE   137,641 0 0
Playtika Holding Corp Common Stock 72815L107 4,297 155,506 SH   SOLE   155,506 0 0
Purple Biotech Ltd ADR 74638P109 3,371 736,019 SH   SOLE   736,019 0 0
Abra Information Technologies Common Stock M0R53V104 3,050 2,530,549 SH   SOLE   2,530,549 0 0
Icecure Medical Ltd Common Stock M53071136 2,734 313,208 SH   SOLE   313,208 0 0
Nayax Ltd Common Stock M7S750100 4,861 1,223,010 SH   SOLE   1,223,010 0 0
Phinergy Ltd Common Stock M7S8CD102 2,033 923,518 SH   SOLE   923,518 0 0
Aquarius Engines AM Ltd Common Stock M1R50V113 2,660 259,744 SH   SOLE   259,744 0 0
Check Cap Ltd Common Stock M2361E203 2,673 3,050,528 SH   SOLE   3,050,528 0 0
Cognyte Software Ltd Common Stock M25133105 2,961 144,092 SH   SOLE   144,092 0 0
Collplant Biotechnologies Ltd Common Stock M2R51X116 3,233 191,290 SH   SOLE   191,290 0 0
Entera Bio Ltd Common Stock M40527109 3,217 683,007 SH   SOLE   683,007 0 0
Innoviz Technologies Ltd Common Stock M5R635108 2,032 352,816 SH   SOLE   352,816 0 0
MediWound Ltd Common Stock M68830104 2,555 764,876 SH   SOLE   764,876 0 0
Monday.com Ltd Common Stock M7S64H106 5,525 16,936 SH   SOLE   16,936 0 0
SimilarWeb Ltd Common Stock M84137104 3,259 155,712 SH   SOLE   155,712 0 0
Tufin Software Technologies Lt Common Stock M8893U102 3,384 344,275 SH   SOLE   344,275 0 0
Vascular Biogenics Ltd Common Stock M96883109 2,857 1,393,460 SH   SOLE   1,393,460 0 0
WalkMe Ltd Common Stock M97628107 3,520 118,336 SH   SOLE   118,336 0 0
Joby Aviation Inc Common Stock G65163100 11,077 1,101,104 SH   SOLE   1,101,104 0 0
General Electric Co Common Stock 369604301 5,734 55,649 SH   SOLE   55,649 0 0
Pfizer Inc Common Stock 717081103 95,382 2,217,669 SH   SOLE   2,217,669 0 0
LivePerson Inc Common Stock 538146101 56,014 950,194 SH   SOLE   950,194 0 0
Genius Sports Ltd Common Stock G3934V109 56,989 3,054,052 SH   SOLE   3,054,052 0 0
Vanguard Growth ETF ETP 922908736 235 809 SH   SOLE   809 0 0
ARK Genomic Revolution ETF ETP 00214Q302 1,189 15,912 SH   SOLE   15,912 0 0
Ginkgo Bioworks Holdings Inc Common Stock 37611X100 269,246 23,230,855 SH   SOLE   22,331,362 577,372 322,121
SomaLogic Inc Common Stock 83444K105 78,482 6,334,312 SH   SOLE   6,334,312 0 0
SomaLogic Inc Common Stock 83444K113 2,928 848,758 SH Call SOLE   848,758 0 0
Archer Aviation Inc Common Stock 03945R102 50,950 5,737,569 SH   SOLE   5,737,569 0 0
Toast Inc Common Stock 888787108 733 14,681 SH   SOLE   14,681 0 0
Velo3D Inc Common Stock 92259N104 33,128 3,957,926 SH   SOLE   3,957,926 0 0
ARK Innovation ETF ETP 00214Q104 928 8,400 SH Call SOLE   8,400 0 0
Coinbase Global Inc Common Stock 19260Q107 569 2,500 SH Call SOLE   2,500 0 0
DraftKings Inc Common Stock 26142R104 409 8,500 SH Call SOLE   8,500 0 0
Intel Corp Common Stock 458140100 272 5,100 SH Put SOLE   5,100 0 0
SPDR S&P Regional Banking ETF ETP 78464A698 379 5,600 SH Put SOLE   5,600 0 0
Pacific Biosciences of Califor Common Stock 69404D108 424 16,600 SH Call SOLE   16,600 0 0
Square Inc Common Stock 852234103 168 700 SH Call SOLE   700 0 0
Tesla Inc Common Stock 88160R101 465 600 SH Call SOLE   600 0 0
Energy Select Sector SPDR Fund ETP 81369Y506 1,401 26,900 SH Put SOLE   26,900 0 0
Zoom Video Communications Inc Common Stock 98980L101 1,935 7,400 SH Call SOLE   7,400 0 0