The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABB LTD SPONSORED ADR 000375204 662,596 19,416,715 SH   DFND 1, 2 19,416,715 0 0
AES CORP COM 00130H105 1,385,536 53,143,577 SH   DFND 1, 2 53,140,595 0 2,982
AES CORP UNIT 99/99/9999 00130H204 224,075 2,083,059 SH   DFND 1, 2 2,083,059 0 0
ABBOTT LABS COM 002824100 6,488,764 55,968,342 SH   DFND 1, 2 55,931,736 0 36,606
ABBVIE INC COM 00287Y109 1,092,460 9,698,683 SH   DFND 1, 2 9,698,683 0 0
ABCELLERA BIOLOGICS INC COM 00288U106 151,670 6,894,089 SH   DFND 1, 2 6,894,089 0 0
ACTIVISION BLIZZARD INC COM 00507V109 2,288,581 23,978,506 SH   DFND 1, 2 23,950,871 0 27,635
ADAGENE INC ADS 005329107 12,520 923,269 SH   DFND 1, 2 923,269 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 80,274 1,964,616 SH   DFND 1, 2 1,964,616 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 5,628 1,321,200 SH   DFND 1, 2 1,321,200 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 1,642,305 2,804,086 SH   DFND 1, 2 2,804,049 0 37
ADVANCED DRAIN SYS INC DEL COM 00790R104 37,659 323,056 SH   DFND 1, 2 323,056 0 0
ADVANCED ENERGY INDS COM 007973100 61,541 546,013 SH   DFND 1, 2 546,013 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 5,284 95,882 SH   DFND 1, 2 95,882 0 0
AIRBNB INC COM CL A 009066101 62,984 411,286 SH   DFND 1, 2 411,286 0 0
AIR LEASE CORP CL A 00912X302 439,528 10,530,129 SH   DFND 1, 2 10,530,129 0 0
AIR PRODS & CHEMS INC COM 009158106 2,218,508 7,711,588 SH   DFND 1, 2 7,699,783 0 11,805
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 120,030 529,121 SH   DFND 1, 2 515,770 0 13,351
ALKAMI TECHNOLOGY INC COM 01644J108 10,701 300,000 SH   DFND 1, 2 300,000 0 0
ALLAKOS INC COM 01671P100 174,637 2,045,653 SH   DFND 1, 2 2,045,653 0 0
ALLEGHENY TECHNOLOGIES INC COM 01741R102 224,695 10,776,721 SH   DFND 1, 2 10,776,721 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 91,935 3,525,114 SH   DFND 1, 2 3,525,114 0 0
ALPHABET INC CAP STK CL C 02079K107 10,388,855 4,144,906 SH   DFND 1, 2 4,144,218 0 688
ALPHABET INC CAP STK CL A 02079K305 4,358,726 1,785,052 SH   DFND 1, 2 1,785,052 0 0
ALTERYX INC COM CL A 02156B103 11,441 133,000 SH   DFND 1, 2 133,000 0 0
ALTRIA GROUP INC COM 02209S103 801,679 16,817,597 SH   DFND 1, 2 16,817,597 0 0
AMAZON COM INC COM 023135106 11,462,214 3,331,848 SH   DFND 1, 2 3,331,836 0 12
AMBEV SA SPONSORED ADR 02319V103 3,881 1,128,200 SH   DFND 1, 2 1,128,200 0 0
AMERICA MOVIL SAB DE CV SPON ADR L SHS 02364W105 959,596 63,954,209 SH   DFND 1, 2 63,786,046 0 168,163
AMERICAN INTL GROUP INC COM NEW 026874784 937,293 19,691,037 SH   DFND 1, 2 19,690,188 0 849
AMERICAN TOWER CORP NEW COM 03027X100 439,076 1,624,604 SH   DFND 1, 2 1,618,089 0 6,515
AMERISOURCEBERGEN CORP COM 03073E105 219,887 1,920,581 SH   DFND 1, 2 1,920,581 0 0
AMETEK INC COM 031100100 499,932 3,745,557 SH   DFND 1, 2 3,743,823 0 1,734
AMGEN INC COM 031162100 526,313 2,159,232 SH   DFND 1, 2 2,159,232 0 0
AMPHENOL CORP NEW CL A 032095101 369,836 5,406,169 SH   DFND 1, 2 5,404,943 0 1,226
ANALOG DEVICES INC COM 032654105 331,482 1,925,432 SH   DFND 1, 2 1,925,432 0 0
ANGLOGOLD ASHANTI LIMITED SPONSORED ADR 035128206 55,387 2,981,008 SH   DFND 1, 2 2,981,008 0 0
ANHEUSER BUSCH INBEV SA/NV SPONSORED ADR 03524A108 919,874 12,752,865 SH   DFND 1, 2 12,700,519 0 52,346
ANTHEM INC COM 036752103 1,765,129 4,623,202 SH   DFND 1, 2 4,611,324 0 11,878
APOLLO GLOBAL MGMT INC COM CL A 03768E105 360,435 5,794,777 SH   DFND 1, 2 5,794,777 0 0
APPLE INC COM 037833100 2,585,298 18,878,106 SH   DFND 1, 2 18,874,338 0 3,768
APPLIED MATLS INC COM 038222105 2,668,988 18,742,933 SH   DFND 1, 2 18,732,721 0 10,212
APPLIED MOLECULAR TRANS INC COM 03824M109 35,462 775,300 SH   DFND 1, 2 775,300 0 0
ARAMARK COM 03852U106 446,275 11,980,533 SH   DFND 1, 2 11,980,533 0 0
ARCOSA INC COM 039653100 156,431 2,663,101 SH   DFND 1, 2 2,663,101 0 0
ARES MANAGEMENT CORPORATION CL A COM STK 03990B101 418,864 6,586,942 SH   DFND 1, 2 6,586,942 0 0
ARMSTRONG WORLD INDS INC NEW COM 04247X102 626,030 5,836,569 SH   DFND 1, 2 5,836,569 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 1,921,014 32,049,323 SH   DFND 1, 2 31,934,021 0 115,302
AVALARA INC COM 05338G106 24,434 151,015 SH   DFND 1, 2 151,015 0 0
AVALONBAY CMNTYS INC COM 053484101 141,510 678,086 SH   DFND 1, 2 678,086 0 0
AVEANNA HEALTHCARE HLDGS INC COM 05356F105 15,413 1,246,000 SH   DFND 1, 2 1,246,000 0 0
AXON ENTERPRISE INC COM 05464C101 8,946 50,600 SH   DFND 1, 2 50,600 0 0
AZUL S A SPONSR ADR PFD 05501U106 10,544 399,394 SH   DFND 1, 2 399,394 0 0
BJS WHSL CLUB HLDGS INC COM 05550J101 69,258 1,455,608 SH   DFND 1, 2 1,455,608 0 0
BWX TECHNOLOGIES INC COM 05605H100 618,338 10,638,985 SH   DFND 1, 2 10,638,985 0 0
BANCO BILBAO VIZCAYA ARGENTA SPONSORED ADR 05946K101 80,997 12,959,447 SH   DFND 1, 2 12,959,447 0 0
BK OF AMERICA CORP COM 060505104 1,257,411 30,497,713 SH   DFND 1, 2 30,469,095 0 28,618
BARRICK GOLD CORP COM 067901108 217,195 10,502,671 SH   DFND 1, 2 10,502,671 0 0
BAXTER INTL INC COM 071813109 858,609 10,665,945 SH   DFND 1, 2 10,665,945 0 0
BEIGENE LTD SPONSORED ADR 07725L102 2,042,640 5,939,650 SH   DFND 1, 2 5,929,898 0 9,752
BERKELEY LTS INC COM 084310101 41,364 923,095 SH   DFND 1, 2 923,095 0 0
BERKSHIRE HATHAWAY INC DEL CL A 084670108 10,884 26 SH   DFND 1, 2 26 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 91,075 327,703 SH   DFND 1, 2 327,698 0 5
BILL COM HLDGS INC COM 090043100 922,344 5,035,178 SH   DFND 1, 2 5,035,178 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 45,729 548,043 SH   DFND 1, 2 544,773 0 3,270
BLACKROCK INC COM 09247X101 2,542,497 2,905,820 SH   DFND 1, 2 2,899,938 0 5,882
BLACKSTONE GROUP INC COM 09260D107 1,597,114 16,441,365 SH   DFND 1, 2 16,441,365 0 0
BOOKING HOLDINGS INC COM 09857L108 390,156 178,309 SH   DFND 1, 2 178,309 0 0
BRIGHT HEALTH GROUP INC COM 10920V107 176,147 10,264,987 SH   DFND 1, 2 10,264,987 0 0
BRITISH AMERN TOB PLC SPONSORED ADR 110448107 394,413 10,017,185 SH   DFND 1, 2 9,979,116 0 38,069
BROADCOM INC COM 11135F101 16,185,173 33,942,430 SH   DFND 1, 2 33,911,414 0 31,016
BROOKFIELD ASSET MGMT INC CL A LTD VT SH 112585104 690,249 13,539,590 SH   DFND 1, 2 13,539,590 0 0
BUMBLE INC COM CL A 12047B105 57,671 1,001,235 SH   DFND 1, 2 1,001,235 0 0
BURLINGTON STORES INC COM 122017106 781,700 2,427,733 SH   DFND 1, 2 2,426,115 0 1,618
CDK GLOBAL INC COM 12508E101 325,442 6,549,447 SH   DFND 1, 2 6,549,447 0 0
CIGNA CORP NEW COM 125523100 583,093 2,459,582 SH   DFND 1, 2 2,459,582 0 0
CMC MATERIALS INC COM 12571T100 119,579 793,277 SH   DFND 1, 2 793,277 0 0
CME GROUP INC COM 12572Q105 2,211,066 10,395,921 SH   DFND 1, 2 10,392,604 0 3,317
CMS ENERGY CORP COM 125896100 620,332 10,500,440 SH   DFND 1, 2 10,488,691 0 11,749
CSW INDUSTRIALS INC COM 126402106 49,246 415,719 SH   DFND 1, 2 415,719 0 0
CSX CORP COM 126408103 455,878 14,228,163 SH   DFND 1, 2 14,141,143 0 87,020
CVS HEALTH CORP COM 126650100 2,286,301 27,400,512 SH   DFND 1, 2 27,358,224 0 42,288
CABLE ONE INC COM 12685J105 221,249 115,839 SH   DFND 1, 2 115,827 0 12
CACTUS INC CL A 127203107 47,765 1,300,791 SH   DFND 1, 2 1,300,791 0 0
CAESARS ENTERTAINMENT INC NE COM 12769G100 459,177 4,425,802 SH   DFND 1, 2 4,425,802 0 0
CANADIAN NATL RY CO COM 136375102 126,850 1,197,137 SH   DFND 1, 2 1,197,137 0 0
CANADIAN NAT RES LTD COM 136385101 152,975 4,214,011 SH   DFND 1, 2 4,214,011 0 0
CARRIER GLOBAL CORPORATION COM 14448C104 2,503,029 51,502,151 SH   DFND 1, 2 51,488,650 0 13,501
CATALENT INC COM 148806102 50,926 471,016 SH   DFND 1, 2 471,016 0 0
CATERPILLAR INC COM 149123101 1,900,063 8,730,705 SH   DFND 1, 2 8,730,705 0 0
CELANESE CORP DEL COM 150870103 877,526 5,788,634 SH   DFND 1, 2 5,782,189 0 6,445
CELLECTIS S A SPON ADS 15117K103 20,720 1,339,336 SH   DFND 1, 2 1,339,336 0 0
CENTENE CORP DEL COM 15135B101 1,463,126 20,061,985 SH   DFND 1, 2 20,055,479 0 6,506
CENTERPOINT ENERGY INC COM 15189T107 789,924 32,215,491 SH   DFND 1, 2 32,215,491 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 7,411,948 10,273,843 SH   DFND 1, 2 10,271,932 0 1,911
CHEVRON CORP NEW COM 166764100 3,987,827 38,077,241 SH   DFND 1, 2 38,034,813 0 42,428
CHIPOTLE MEXICAN GRILL INC COM 169656105 1,320,566 851,948 SH   DFND 1, 2 851,936 0 12
CHURCH & DWIGHT INC COM 171340102 1,008,874 11,838,464 SH   DFND 1, 2 11,838,464 0 0
CISCO SYS INC COM 17275R102 116,954 2,206,678 SH   DFND 1, 2 2,206,678 0 0
CITIGROUP INC COM NEW 172967424 49,764 703,374 SH   DFND 1, 2 703,374 0 0
CITIZENS FINL GROUP INC COM 174610105 889,316 19,388,772 SH   DFND 1, 2 19,388,772 0 0
CLOROX CO DEL COM 189054109 176,595 981,572 SH   DFND 1, 2 981,572 0 0
COCA COLA CO COM 191216100 15,771 291,465 SH   DFND 1, 2 291,275 0 190
COGNEX CORP COM 192422103 44,547 530,000 SH   DFND 1, 2 530,000 0 0
COLGATE PALMOLIVE CO COM 194162103 81,125 997,239 SH   DFND 1, 2 997,239 0 0
COMCAST CORP NEW CL A 20030N101 12,895,902 226,174,387 SH   DFND 1, 2 225,935,552 0 238,835
CONCENTRIX CORP COM 20602D101 455,853 2,834,908 SH   DFND 1, 2 2,834,908 0 0
CONOCOPHILLIPS COM 20825C104 4,342,671 71,315,736 SH   DFND 1, 2 71,300,432 0 15,304
CONSTELLATION BRANDS INC CL A 21036P108 232,424 993,732 SH   DFND 1, 2 993,732 0 0
CORTEXYME INC COM 22053A107 145,043 2,736,669 SH   DFND 1, 2 2,736,669 0 0
COSTCO WHSL CORP NEW COM 22160K105 533,091 1,346,859 SH   DFND 1, 2 1,343,588 0 3,271
CREE INC COM 225447101 994,174 10,151,880 SH   DFND 1, 2 10,151,880 0 0
CROWN CASTLE INTL CORP NEW COM 22822V101 3,583,231 18,362,162 SH   DFND 1, 2 18,361,440 0 722
CUMMINS INC COM 231021106 109,707 449,969 SH   DFND 1, 2 449,969 0 0
D R HORTON INC COM 23331A109 93,119 1,030,418 SH   DFND 1, 2 1,030,418 0 0
DANAHER CORPORATION COM 235851102 2,117,477 7,889,048 SH   DFND 1, 2 7,888,974 0 74
DANIMER SCIENTIFIC INC COM CL A 236272100 22,287 889,717 SH   DFND 1, 2 889,717 0 0
DARDEN RESTAURANTS INC COM 237194105 1,741,960 11,932,101 SH   DFND 1, 2 11,928,892 0 3,209
DEERE & CO COM 244199105 79,164 224,666 SH   DFND 1, 2 224,666 0 0
DEL TACO RESTAURANTS INC NEW COM 245496104 24,050 2,402,550 SH   DFND 1, 2 2,402,550 0 0
DEXCOM INC COM 252131107 149,319 349,694 SH   DFND 1, 2 349,694 0 0
DIAGEO PLC SPON ADR NEW 25243Q205 75,931 393,679 SH   DFND 1, 2 393,679 0 0
DIGITAL RLTY TR INC COM 253868103 1,536,034 10,207,457 SH   DFND 1, 2 10,201,518 0 5,939
DIGITALBRIDGE GROUP INC CL A COM 25401T108 189,985 24,048,774 SH   DFND 1, 2 24,048,774 0 0
DISCOVER FINL SVCS COM 254709108 2,438,214 20,614,044 SH   DFND 1, 2 20,613,547 0 497
DOLLAR GEN CORP NEW COM 256677105 1,162,849 5,373,654 SH   DFND 1, 2 5,373,569 0 85
DOLLAR TREE INC COM 256746108 262,387 2,637,051 SH   DFND 1, 2 2,637,051 0 0
DOW INC COM 260557103 2,108,462 33,320,373 SH   DFND 1, 2 33,256,299 0 64,074
DUCK CREEK TECHNOLOGIES INC SHS 264120106 63,912 1,468,897 SH   DFND 1, 2 1,468,897 0 0
DUN & BRADSTREET HLDGS INC COM 26484T106 485,735 22,729,761 SH   DFND 1, 2 22,729,761 0 0
EOG RES INC COM 26875P101 4,487,284 53,783,237 SH   DFND 1, 2 53,768,416 0 14,821
EARGO INC COM 270087109 20,670 517,918 SH   DFND 1, 2 517,918 0 0
EAST WEST BANCORP INC COM 27579R104 862,692 12,033,194 SH   DFND 1, 2 12,033,194 0 0
EDISON INTL COM 281020107 158,145 2,735,127 SH   DFND 1, 2 2,735,127 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 2,071,700 20,002,880 SH   DFND 1, 2 20,002,755 0 125
ELECTRONIC ARTS INC COM 285512109 403,814 2,807,571 SH   DFND 1, 2 2,807,571 0 0
ENBRIDGE INC COM 29250N105 2,584,850 64,558,479 SH   DFND 1, 2 64,327,667 0 230,812
ENDAVA PLC ADS 29260V105 126,652 1,117,062 SH   DFND 1, 2 1,117,062 0 0
ENPHASE ENERGY INC COM 29355A107 348,984 1,900,473 SH   DFND 1, 2 1,900,473 0 0
ENPRO INDS INC COM 29355X107 78,705 810,134 SH   DFND 1, 2 810,134 0 0
ENTERGY CORP NEW COM 29364G103 412,419 4,136,602 SH   DFND 1, 2 4,136,602 0 0
EPAM SYS INC COM 29414B104 163,557 320,097 SH   DFND 1, 2 320,097 0 0
EQUIFAX INC COM 294429105 1,856,817 7,752,572 SH   DFND 1, 2 7,742,984 0 9,588
EQUINIX INC COM 29444U700 1,926,341 2,400,151 SH   DFND 1, 2 2,397,056 0 3,095
EQUITRANS MIDSTREAM CORP COM 294600101 340,858 40,066,778 SH   DFND 1, 2 40,066,778 0 0
ESCO TECHNOLOGIES INC COM 296315104 52,366 558,209 SH   DFND 1, 2 558,209 0 0
EURONET WORLDWIDE INC COM 298736109 156,892 1,159,130 SH   DFND 1, 2 1,159,130 0 0
EVERTEC INC COM 30040P103 110,291 2,526,723 SH   DFND 1, 2 2,526,723 0 0
EXELON CORP COM 30161N101 2,635,628 59,480,240 SH   DFND 1, 2 59,480,007 0 233
EXTRA SPACE STORAGE INC COM 30225T102 146,727 895,500 SH   DFND 1, 2 895,500 0 0
FIGS INC CL A 30260D103 50,100 1,000,000 SH   DFND 1, 2 1,000,000 0 0
FTI CONSULTING INC COM 302941109 132,950 973,206 SH   DFND 1, 2 973,206 0 0
FACEBOOK INC CL A 30303M102 16,965,211 48,790,238 SH   DFND 1, 2 48,756,577 0 33,661
FAIR ISAAC CORP COM 303250104 14,628 29,100 SH   DFND 1, 2 29,100 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 3,579,450 25,265,736 SH   DFND 1, 2 25,265,623 0 113
FIRST REP BK SAN FRANCISCO C COM 33616C100 1,569,801 8,387,088 SH   DFND 1, 2 8,383,757 0 3,331
FLEETCOR TECHNOLOGIES INC COM 339041105 593,085 2,316,430 SH   DFND 1, 2 2,312,959 0 3,471
FORTIS INC COM 349553107 290 6,560 SH   DFND 1, 2 6,560 0 0
FRONTIER COMMUNICATIONS PARE COM 35909D109 11,591 439,057 SH   DFND 1, 2 439,057 0 0
GALAPAGOS NV SPON ADR 36315X101 119,277 1,731,410 SH   DFND 1, 2 1,731,410 0 0
GALLAGHER ARTHUR J & CO COM 363576109 714,005 5,096,687 SH   DFND 1, 2 5,096,625 0 62
GAMING & LEISURE PPTYS INC COM 36467J108 701,786 15,149,239 SH   DFND 1, 2 15,149,239 0 0
GENERAC HLDGS INC COM 368736104 278,877 671,751 SH   DFND 1, 2 671,751 0 0
GENERAL DYNAMICS CORP COM 369550108 233,584 1,240,750 SH   DFND 1, 2 1,240,750 0 0
GENERAL MLS INC COM 370334104 1,673,177 27,462,315 SH   DFND 1, 2 27,462,315 0 0
GENMAB A/S SPONSORED ADS 372303206 146,219 3,527,156 SH   DFND 1, 2 3,527,156 0 0
GERDAU SA SPON ADR REP PFD 373737105 598,528 101,432,791 SH   DFND 1, 2 101,018,254 0 414,537
GILEAD SCIENCES INC COM 375558103 2,715,333 39,436,987 SH   DFND 1, 2 39,390,907 0 46,080
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 902,988 22,676,745 SH   DFND 1, 2 22,674,667 0 2,078
GLOBAL PMTS INC COM 37940X102 331,724 1,768,815 SH   DFND 1, 2 1,768,815 0 0
GODADDY INC CL A 380237107 1,164,984 13,391,679 SH   DFND 1, 2 13,372,064 0 19,615
GOL LINHAS AEREAS INTELIGENT SPON ADR PFD NEW 38045R206 9,446 1,024,490 SH   DFND 1, 2 1,024,490 0 0
GOODRX HLDGS INC COM CL A 38246G108 19,437 539,771 SH   DFND 1, 2 539,771 0 0
GOOSEHEAD INS INC COM CL A 38267D109 63,713 500,495 SH   DFND 1, 2 500,495 0 0
GRACELL BIOTECHNOLOGIES INC SPONSORED ADS 38406L103 14,593 1,122,533 SH   DFND 1, 2 1,122,533 0 0
GRACO INC COM 384109104 31,794 420,000 SH   DFND 1, 2 420,000 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 36,492 2,094,570 SH   DFND 1, 2 2,094,570 0 0
GUARDANT HEALTH INC COM 40131M109 247,593 1,993,662 SH   DFND 1, 2 1,993,662 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 82,124 1,115,067 SH   DFND 1, 2 1,091,830 0 23,237
HAMILTON LANE INC CL A 407497106 17,200 188,760 SH   DFND 1, 2 188,760 0 0
HEICO CORP NEW COM 422806109 144,520 1,036,582 SH   DFND 1, 2 1,036,582 0 0
HEICO CORP NEW CL A 422806208 129,646 1,043,103 SH   DFND 1, 2 1,043,026 0 77
HENRY JACK & ASSOC INC COM 426281101 28,478 173,443 SH   DFND 1, 2 173,369 0 74
HILTON GRAND VACATIONS INC COM 43283X105 302,003 7,296,531 SH   DFND 1, 2 7,296,531 0 0
HILTON WORLDWIDE HLDGS INC COM 43300A203 1,808,221 14,994,174 SH   DFND 1, 2 14,977,492 0 16,682
HOME DEPOT INC COM 437076102 872,859 2,737,180 SH   DFND 1, 2 2,736,965 0 215
HONEYWELL INTL INC COM 438516106 1,756,812 8,010,886 SH   DFND 1, 2 7,993,050 0 17,836
HORMEL FOODS CORP COM 440452100 525,123 10,997,612 SH   DFND 1, 2 10,937,313 0 60,299
HUAZHU GROUP LTD SPONSORED ADS 44332N106 123,970 2,347,474 SH   DFND 1, 2 2,347,474 0 0
HUMANA INC COM 444859102 1,781,940 4,025,016 SH   DFND 1, 2 4,012,923 0 12,093
HUTCHMED CHINA LTD SPONSORED ADS 44842L103 261,785 6,859,817 SH   DFND 1, 2 6,859,817 0 0
ICF INTL INC COM 44925C103 23,838 271,320 SH   DFND 1, 2 271,320 0 0
ITT INC COM 45073V108 505,353 5,517,559 SH   DFND 1, 2 5,517,559 0 0
ICICI BANK LIMITED ADR 45104G104 495,544 28,975,848 SH   DFND 1, 2 28,567,083 0 408,765
IDEXX LABS INC COM 45168D104 201,302 318,742 SH   DFND 1, 2 318,742 0 0
INARI MED INC COM 45332Y109 47,764 512,050 SH   DFND 1, 2 512,050 0 0
INCYTE CORP COM 45337C102 344,639 4,096,504 SH   DFND 1, 2 4,096,494 0 10
INFOSYS LTD SPONSORED ADR 456788108 424,734 20,041,666 SH   DFND 1, 2 19,844,258 0 197,408
ING GROEP N.V. SPONSORED ADR 456837103 38,431 2,898,279 SH   DFND 1, 2 2,898,279 0 0
INSULET CORP COM 45784P101 21,384 77,900 SH   DFND 1, 2 77,900 0 0
INTEL CORP COM 458140100 5,897,593 105,043,103 SH   DFND 1, 2 104,946,206 0 96,897
INTERCONTINENTAL EXCHANGE IN COM 45866F104 2,542,549 21,419,817 SH   DFND 1, 2 21,382,720 0 37,097
INTERNATIONAL BUSINESS MACHS COM 459200101 33,875 231,088 SH   DFND 1, 2 231,088 0 0
INTERNATIONAL FLAVORS&FRAGRA COM 459506101 875,894 5,862,749 SH   DFND 1, 2 5,862,140 0 609
INTUIT COM 461202103 89,776 183,153 SH   DFND 1, 2 183,153 0 0
IRIDIUM COMMUNICATIONS INC COM 46269C102 297,209 7,432,090 SH   DFND 1, 2 7,432,090 0 0
ISHARES TR CORE S&P500 ETF 464287200 11,121 25,890 SH   DFND 1, 2 17,256 0 8,634
ISHARES TR MSCI EAFE ETF 464287465 13,112 164,954 SH   DFND 1, 2 164,954 0 0
ISHARES TR RUS 1000 ETF 464287622 228 940 SH   DFND 1, 2 940 0 0
ISHARES TR MSCI ACWI ETF 464288257 2,815 27,713 SH   DFND 1, 2 25,302 0 2,411
JPMORGAN CHASE & CO COM 46625H100 6,146,639 39,521,621 SH   DFND 1, 2 39,493,141 0 28,480
JACOBS ENGR GROUP INC COM 469814107 526,509 3,946,252 SH   DFND 1, 2 3,946,252 0 0
JAMF HLDG CORP COM 47074L105 4,196 125,000 SH   DFND 1, 2 125,000 0 0
JOHNSON & JOHNSON COM 478160104 3,155,503 19,154,622 SH   DFND 1, 2 19,118,532 0 36,090
KLA CORP COM NEW 482480100 2,477,783 7,642,131 SH   DFND 1, 2 7,642,081 0 50
KKR & CO INC COM 48251W104 1,516,586 25,600,712 SH   DFND 1, 2 25,600,712 0 0
KADANT INC COM 48282T104 73,651 418,259 SH   DFND 1, 2 418,259 0 0
KARUNA THERAPEUTICS INC COM 48576A100 8,960 78,600 SH   DFND 1, 2 78,600 0 0
KEURIG DR PEPPER INC COM 49271V100 1,588,848 45,086,484 SH   DFND 1, 2 45,084,350 0 2,134
KEYCORP COM 493267108 1,472,705 71,317,436 SH   DFND 1, 2 71,317,436 0 0
KONINKLIJKE PHILIPS N V NY REGIS SHS NEW 500472303 105,152 2,105,353 SH   DFND 1, 2 2,072,649 0 32,704
KRAFT HEINZ CO COM 500754106 704,263 17,269,823 SH   DFND 1, 2 17,269,823 0 0
KRATOS DEFENSE & SEC SOLUTIO COM NEW 50077B207 118,394 4,155,647 SH   DFND 1, 2 4,155,647 0 0
KRONOS BIO INC COM 50107A104 14,370 600,000 SH   DFND 1, 2 600,000 0 0
KULICKE & SOFFA INDS INC COM 501242101 298,051 4,870,110 SH   DFND 1, 2 4,870,110 0 0
LGI HOMES INC COM 50187T106 160,577 991,583 SH   DFND 1, 2 991,583 0 0
L3HARRIS TECHNOLOGIES INC COM 502431109 1,793,823 8,299,113 SH   DFND 1, 2 8,298,682 0 431
LAM RESEARCH CORP COM 512807108 206,789 317,763 SH   DFND 1, 2 317,751 0 12
LAS VEGAS SANDS CORP COM 517834107 86,575 1,645,819 SH   DFND 1, 2 1,645,819 0 0
LAUDER ESTEE COS INC CL A 518439104 448,883 1,411,326 SH   DFND 1, 2 1,411,275 0 51
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 110,254 2,685,851 SH   DFND 1, 2 2,685,851 0 0
LESLIES INC COM 527064109 52,250 1,900,706 SH   DFND 1, 2 1,900,706 0 0
LIBERTY BROADBAND CORP COM SER C 530307305 64,727 372,723 SH   DFND 1, 2 372,723 0 0
LIGHTSPEED POS INC SUB VTG SHS 53227R106 152,559 1,823,456 SH   DFND 1, 2 1,823,456 0 0
LILLY ELI & CO COM 532457108 1,954,809 8,517,079 SH   DFND 1, 2 8,516,978 0 101
LIVERAMP HLDGS INC COM 53815P108 65,351 1,394,899 SH   DFND 1, 2 1,394,899 0 0
LOCKHEED MARTIN CORP COM 539830109 678,143 1,792,566 SH   DFND 1, 2 1,792,354 0 212
LOMA NEGRA C I A S A MTN 14 SPONSORED ADS 54150E104 56,670 8,321,654 SH   DFND 1, 2 8,321,654 0 0
LOWES COS INC COM 548661107 122,965 633,938 SH   DFND 1, 2 633,938 0 0
MGIC INVT CORP WIS COM 552848103 42,181 3,101,550 SH   DFND 1, 2 3,101,550 0 0
MGM GROWTH PPTYS LLC CL A COM 55303A105 37,566 1,025,842 SH   DFND 1, 2 1,025,842 0 0
MKS INSTRS INC COM 55306N104 642,506 3,610,598 SH   DFND 1, 2 3,610,598 0 0
MSCI INC COM 55354G100 762,942 1,430,804 SH   DFND 1, 2 1,430,780 0 24
MAGNOLIA OIL & GAS CORP CL A 559663109 31,260 2,000,000 SH   DFND 1, 2 2,000,000 0 0
MARKETAXESS HLDGS INC COM 57060D108 13,537 29,200 SH   DFND 1, 2 29,200 0 0
MARSH & MCLENNAN COS INC COM 571748102 3,089,496 21,960,501 SH   DFND 1, 2 21,906,670 0 53,831
MARRIOTT INTL INC NEW CL A 571903202 279,815 2,049,623 SH   DFND 1, 2 2,049,623 0 0
MASTERCARD INCORPORATED CL A 57636Q104 4,712,941 12,908,942 SH   DFND 1, 2 12,903,849 0 5,093
MATTEL INC COM 577081102 142,062 7,067,771 SH   DFND 1, 2 7,067,771 0 0
MERCADOLIBRE INC COM 58733R102 699,568 447,821 SH   DFND 1, 2 447,821 0 0
MERCK & CO INC COM 58933Y105 2,248,586 28,915,476 SH   DFND 1, 2 28,843,225 0 72,251
METTLER TOLEDO INTERNATIONAL COM 592688105 726,749 524,600 SH   DFND 1, 2 524,600 0 0
MICROSOFT CORP COM 594918104 25,166,309 92,898,047 SH   DFND 1, 2 92,831,261 0 66,786
MICROSTRATEGY INC CL A NEW 594972408 633,429 953,242 SH   DFND 1, 2 953,242 0 0
MICRON TECHNOLOGY INC COM 595112103 1,696,655 19,965,598 SH   DFND 1, 2 19,955,965 0 9,633
MOLINA HEALTHCARE INC COM 60855R100 250,163 988,551 SH   DFND 1, 2 988,551 0 0
MOLSON COORS BEVERAGE CO CL B 60871R209 245,746 4,577,120 SH   DFND 1, 2 4,577,120 0 0
MOMENTIVE GLOBAL INC COM 60878Y108 59,898 2,842,821 SH   DFND 1, 2 2,842,821 0 0
MONDELEZ INTL INC CL A 609207105 886,921 14,204,562 SH   DFND 1, 2 14,204,416 0 146
MONGODB INC CL A 60937P106 210,294 581,693 SH   DFND 1, 2 581,693 0 0
MONSTER BEVERAGE CORP NEW COM 61174X109 18,309 200,424 SH   DFND 1, 2 200,424 0 0
MOODYS CORP COM 615369105 1,948,057 5,374,945 SH   DFND 1, 2 5,369,025 0 5,920
NMI HLDGS INC CL A 629209305 31,763 1,412,927 SH   DFND 1, 2 1,412,927 0 0
NVR INC COM 62944T105 865,389 174,007 SH   DFND 1, 2 174,007 0 0
NASDAQ INC COM 631103108 102,286 581,831 SH   DFND 1, 2 581,831 0 0
NCINO INC COM 63947U107 10,037 167,500 SH   DFND 1, 2 167,500 0 0
NETAPP INC COM 64110D104 2,052,958 25,089,025 SH   DFND 1, 2 25,089,025 0 0
NETFLIX INC COM 64110L106 10,144,956 19,206,004 SH   DFND 1, 2 19,201,028 0 4,976
NETEASE INC SPONSORED ADS 64110W102 181,293 1,574,918 SH   DFND 1, 2 1,555,926 0 18,992
NEUROCRINE BIOSCIENCES INC COM 64125C109 108,625 1,116,163 SH   DFND 1, 2 1,116,163 0 0
NEWELL BRANDS INC COM 651229106 25,669 934,453 SH   DFND 1, 2 934,453 0 0
NEWMONT CORP COM 651639106 64,590 1,019,095 SH   DFND 1, 2 1,019,095 0 0
NEXTERA ENERGY INC COM 65339F101 815,482 11,128,149 SH   DFND 1, 2 11,114,602 0 13,547
NEXTERA ENERGY INC UNIT 09/01/2022S 65339F796 80,283 1,429,787 SH   DFND 1, 2 1,429,787 0 0
NICE LTD SPONSORED ADR 653656108 202,055 816,515 SH   DFND 1, 2 816,515 0 0
NIKE INC CL B 654106103 1,156,572 7,485,104 SH   DFND 1, 2 7,478,133 0 6,971
NORFOLK SOUTHN CORP COM 655844108 1,522,873 5,738,869 SH   DFND 1, 2 5,726,986 0 11,883
NORTHROP GRUMMAN CORP COM 666807102 4,912,139 13,517,111 SH   DFND 1, 2 13,496,030 0 21,081
NOVAVAX INC COM NEW 670002401 49,893 235,000 SH   DFND 1, 2 235,000 0 0
NOVANTA INC COM 67000B104 91,785 681,098 SH   DFND 1, 2 681,098 0 0
NOVO-NORDISK A S ADR 670100205 447,663 5,342,888 SH   DFND 1, 2 5,316,912 0 25,976
NUCANA PLC SPONSORED ADR 67022C106 12,236 4,417,153 SH   DFND 1, 2 4,417,153 0 0
NUCOR CORP COM 670346105 87,309 910,216 SH   DFND 1, 2 904,225 0 5,991
NVIDIA CORPORATION COM 67066G104 54,860 68,566 SH   DFND 1, 2 68,566 0 0
OAK STR HEALTH INC COM 67181A107 519,829 8,875,349 SH   DFND 1, 2 8,875,349 0 0
OKTA INC CL A 679295105 592,284 2,420,646 SH   DFND 1, 2 2,420,646 0 0
OLD DOMINION FREIGHT LINE IN COM 679580100 255,606 1,007,114 SH   DFND 1, 2 1,007,114 0 0
OLINK HLDG AB SPONSORED ADS 680710100 40,518 1,177,156 SH   DFND 1, 2 1,177,156 0 0
ON SEMICONDUCTOR CORP COM 682189105 677,130 17,688,870 SH   DFND 1, 2 17,688,870 0 0
ORGANON & CO COMMON STOCK 68622V106 64,464 2,130,341 SH   DFND 1, 2 2,130,295 0 46
PG&E CORP COM 69331C108 261,704 25,732,954 SH   DFND 1, 2 25,732,954 0 0
PNC FINL SVCS GROUP INC COM 693475105 3,218,928 16,874,377 SH   DFND 1, 2 16,849,418 0 24,959
PPG INDS INC COM 693506107 780,280 4,596,099 SH   DFND 1, 2 4,596,099 0 0
PACCAR INC COM 693718108 244,222 2,736,376 SH   DFND 1, 2 2,736,376 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 306,942 8,777,304 SH   DFND 1, 2 8,777,304 0 0
PARK HOTELS & RESORTS INC COM 700517105 100,019 4,852,938 SH   DFND 1, 2 4,852,938 0 0
PAYCHEX INC COM 704326107 1,589,902 14,817,219 SH   DFND 1, 2 14,817,219 0 0
PAYMENTUS HOLDINGS INC COM CL A 70439P108 26,625 750,000 SH   DFND 1, 2 750,000 0 0
PAYPAL HLDGS INC COM 70450Y103 951,227 3,263,439 SH   DFND 1, 2 3,263,439 0 0
PEBBLEBROOK HOTEL TR COM 70509V100 99,567 4,227,915 SH   DFND 1, 2 4,227,915 0 0
PEPSICO INC COM 713448108 457,231 3,086,199 SH   DFND 1, 2 3,086,199 0 0
PFIZER INC COM 717081103 47,755 1,219,493 SH   DFND 1, 2 1,219,493 0 0
PHILIP MORRIS INTL INC COM 718172109 7,388,259 74,551,934 SH   DFND 1, 2 74,551,017 0 917
PHREESIA INC COM 71944F106 48,757 795,384 SH   DFND 1, 2 795,384 0 0
PINTEREST INC CL A 72352L106 593,253 7,514,286 SH   DFND 1, 2 7,514,286 0 0
PIONEER NAT RES CO COM 723787107 839,593 5,166,661 SH   DFND 1, 2 5,143,255 0 23,406
POOL CORP COM 73278L105 71,963 156,898 SH   DFND 1, 2 156,898 0 0
POTLATCHDELTIC CORPORATION COM 737630103 53,150 1,000,000 SH   DFND 1, 2 1,000,000 0 0
PROCTER AND GAMBLE CO COM 742718109 743,798 5,512,471 SH   DFND 1, 2 5,512,410 0 61
PRIVIA HEALTH GROUP INC COM 74276R102 57,686 1,300,114 SH   DFND 1, 2 1,300,114 0 0
QUALCOMM INC COM 747525103 586,718 4,105,095 SH   DFND 1, 2 4,105,095 0 0
QUALTRICS INTL INC COM CL A 747601201 66,932 1,749,845 SH   DFND 1, 2 1,749,845 0 0
QUANTUM SI INC COM CL A 74765K105 26,972 2,500,000 SH   DFND 1, 2 2,500,000 0 0
RADIAN GROUP INC COM 750236101 61,827 2,778,751 SH   DFND 1, 2 2,778,751 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 2,746,888 32,200,638 SH   DFND 1, 2 32,199,581 0 1,057
REGENERON PHARMACEUTICALS COM 75886F107 720,598 1,290,146 SH   DFND 1, 2 1,290,146 0 0
RELX PLC SPONSORED ADR 759530108 359,794 13,497,476 SH   DFND 1, 2 13,497,476 0 0
RESIDEO TECHNOLOGIES INC COM 76118Y104 55,155 1,838,512 SH   DFND 1, 2 1,838,512 0 0
REVANCE THERAPEUTICS INC COM 761330109 45,812 1,545,630 SH   DFND 1, 2 1,545,630 0 0
RINGCENTRAL INC CL A 76680R206 863,936 2,973,144 SH   DFND 1, 2 2,973,144 0 0
RIO TINTO PLC SPONSORED ADR 767204100 236,640 2,818,404 SH   DFND 1, 2 2,818,404 0 0
RUBIUS THERAPEUTICS INC COM 78116T103 10,164 416,396 SH   DFND 1, 2 416,396 0 0
RYANAIR HOLDINGS PLC SPONSORED ADS 783513203 1,067,172 9,862,764 SH   DFND 1, 2 9,849,827 0 12,937
S&P GLOBAL INC COM 78409V104 2,041,840 4,974,638 SH   DFND 1, 2 4,974,226 0 412
SPDR S&P 500 ETF TR TR UNIT 78462F103 1,986 4,644 SH   DFND 1, 2 3,070 0 1,574
SVB FINANCIAL GROUP COM 78486Q101 1,139,891 2,048,580 SH   DFND 1, 2 2,048,580 0 0
SAIA INC COM 78709Y105 137,632 656,988 SH   DFND 1, 2 656,988 0 0
SANA BIOTECHNOLOGY INC COM 799566104 23,592 1,200,000 SH   DFND 1, 2 1,200,000 0 0
SANDSTORM GOLD LTD COM NEW 80013R206 20,829 2,639,868 SH   DFND 1, 2 2,639,868 0 0
SAP SE SPON ADR 803054204 302,284 2,137,750 SH   DFND 1, 2 2,132,211 0 5,539
SCHLUMBERGER LTD COM STK 806857108 652,871 20,396,784 SH   DFND 1, 2 20,333,189 0 63,595
SCHRODINGER INC COM 80810D103 17,548 232,084 SH   DFND 1, 2 232,084 0 0
SEA LTD SPONSORD ADS 81141R100 402,378 1,465,234 SH   DFND 1, 2 1,463,286 0 1,948
SEAGEN INC COM 81181C104 2,496,377 15,810,865 SH   DFND 1, 2 15,800,521 0 10,344
SEER INC COM CL A 81578P106 17,855 544,694 SH   DFND 1, 2 544,694 0 0
SEMPRA ENERGY COM 816851109 2,809,426 21,204,607 SH   DFND 1, 2 21,173,826 0 30,781
SENTINELONE INC CL A 81730H109 85,000 2,000,000 SH   DFND 1, 2 2,000,000 0 0
SERVICENOW INC COM 81762P102 1,574,331 2,864,678 SH   DFND 1, 2 2,859,553 0 5,125
SHAW COMMUNICATIONS INC CL B CONV 82028K200 333 11,481 SH   DFND 1, 2 11,481 0 0
SHERWIN WILLIAMS CO COM 824348106 465,460 1,708,379 SH   DFND 1, 2 1,708,342 0 37
SHOPIFY INC CL A 82509L107 195,827 134,038 SH   DFND 1, 2 134,038 0 0
SIGNIFY HEALTH INC CL A COM 82671G100 30,430 1,000,000 SH   DFND 1, 2 1,000,000 0 0
SIMPSON MFG INC COM 829073105 29,868 270,449 SH   DFND 1, 2 270,449 0 0
SIX FLAGS ENTMT CORP NEW COM 83001A102 130,201 3,008,335 SH   DFND 1, 2 3,008,335 0 0
SMARTSHEET INC COM CL A 83200N103 110,381 1,526,283 SH   DFND 1, 2 1,526,283 0 0
SOUTH ST CORP COM 840441109 76,958 941,264 SH   DFND 1, 2 941,264 0 0
SQUARE INC CL A 852234103 266,343 1,092,467 SH   DFND 1, 2 1,092,467 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 43,783 287,104 SH   DFND 1, 2 287,104 0 0
STATE STR CORP COM 857477103 535,992 6,514,359 SH   DFND 1, 2 6,514,187 0 172
STMICROELECTRONICS N V NY REGISTRY 861012102 74,713 2,004,097 SH   DFND 1, 2 1,941,080 0 63,017
SUMMIT MATLS INC CL A 86614U100 86,566 2,483,958 SH   DFND 1, 2 2,483,958 0 0
SUN CTRY AIRLS HLDGS INC COM 866683105 70,270 1,898,674 SH   DFND 1, 2 1,898,674 0 0
SUN LIFE FINANCIAL INC. COM 866796105 277 5,374 SH   DFND 1, 2 5,374 0 0
SUNCOR ENERGY INC NEW COM 867224107 265,626 11,090,252 SH   DFND 1, 2 11,090,252 0 0
TFI INTL INC COM 87241L109 453,121 4,947,923 SH   DFND 1, 2 4,947,923 0 0
TJX COS INC NEW COM 872540109 353,119 5,237,606 SH   DFND 1, 2 5,237,606 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 4,158,619 34,607,357 SH   DFND 1, 2 34,572,510 0 34,847
TC ENERGY CORP COM 87807B107 1,375,467 27,787,095 SH   DFND 1, 2 27,787,095 0 0
TELUS CORPORATION COM 87971M103 481 21,463 SH   DFND 1, 2 21,463 0 0
TELUS INTL CDA INC SUB VTG SHS 87975H100 150,432 4,835,567 SH   DFND 1, 2 4,835,567 0 0
TERADATA CORP DEL COM 88076W103 115,528 2,311,952 SH   DFND 1, 2 2,311,952 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 98,987 9,998,702 SH   DFND 1, 2 9,998,692 0 10
TEXAS INSTRS INC COM 882508104 864,549 4,495,732 SH   DFND 1, 2 4,495,722 0 10
THERMO FISHER SCIENTIFIC INC COM 883556102 431,189 854,723 SH   DFND 1, 2 853,083 0 1,640
TOLL BROTHERS INC COM 889478103 104,556 1,808,615 SH   DFND 1, 2 1,808,615 0 0
TOPBUILD CORP COM 89055F103 55,657 281,411 SH   DFND 1, 2 281,411 0 0
TORONTO DOMINION BK ONT COM NEW 891160509 84,258 1,202,821 SH   DFND 1, 2 1,202,821 0 0
TOTALENERGIES SE SPONSORED ADS 89151E109 95,659 2,093,664 SH   DFND 1, 2 2,047,338 0 46,326
TRANSDIGM GROUP INC COM 893641100 4,208,741 6,502,181 SH   DFND 1, 2 6,500,547 0 1,634
TRAVELERS COMPANIES INC COM 89417E109 2,337,242 15,611,793 SH   DFND 1, 2 15,611,793 0 0
TRIMBLE INC COM 896239100 1,492,057 18,233,130 SH   DFND 1, 2 18,199,769 0 33,361
TRINITY INDS INC COM 896522109 344,232 12,822,409 SH   DFND 1, 2 12,822,409 0 0
TRIP COM GROUP LTD ADS 89677Q107 400,764 11,301,830 SH   DFND 1, 2 11,278,410 0 23,420
TRUPANION INC COM 898202106 48,592 422,174 SH   DFND 1, 2 422,174 0 0
TRUIST FINL CORP COM 89832Q109 2,561,288 46,151,003 SH   DFND 1, 2 46,067,128 0 83,875
TUSIMPLE HLDGS INC CL A 90089L108 581,577 8,163,629 SH   DFND 1, 2 8,163,629 0 0
UFP INDUSTRIES INC COM 90278Q108 22,444 301,905 SH   DFND 1, 2 301,905 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 520,349 5,457,124 SH   DFND 1, 2 5,443,912 0 13,212
UNILEVER PLC SPON ADR NEW 904767704 294,574 5,032,077 SH   DFND 1, 2 5,032,077 0 0
UNION PAC CORP COM 907818108 1,562,899 7,106,488 SH   DFND 1, 2 7,082,783 0 23,705
UNITED PARCEL SERVICE INC CL B 911312106 189,767 912,474 SH   DFND 1, 2 912,474 0 0
UNITEDHEALTH GROUP INC COM 91324P102 7,374,618 18,417,306 SH   DFND 1, 2 18,403,494 0 13,812
UPSTART HLDGS INC COM 91680M107 44,023 352,465 SH   DFND 1, 2 352,465 0 0
UPWORK INC COM 91688F104 45,306 777,246 SH   DFND 1, 2 777,246 0 0
V F CORP COM 918204108 741,842 9,042,656 SH   DFND 1, 2 9,024,941 0 17,715
VAIL RESORTS INC COM 91879Q109 263,081 831,166 SH   DFND 1, 2 831,166 0 0
VALE S A SPONSORED ADS 91912E105 4,441,305 194,710,171 SH   DFND 1, 2 194,487,523 0 222,648
VANGUARD TAX-MANAGED INTL FD FTSE DEV MKT ETF 921943858 6,449 124,323 SH   DFND 1, 2 124,321 0 2
VANGUARD INTL EQUITY INDEX F TT WRLD ST ETF 922042742 7,974 76,752 SH   DFND 1, 2 68,156 0 8,596
VANGUARD INTL EQUITY INDEX F ALLWRLD EX US 922042775 267 4,178 SH   DFND 1, 2 884 0 3,294
VERISIGN INC COM 92343E102 1,320,130 5,797,927 SH   DFND 1, 2 5,797,927 0 0
VERIZON COMMUNICATIONS INC COM 92343V104 632,763 11,293,479 SH   DFND 1, 2 11,240,480 0 52,999
VERTEX PHARMACEUTICALS INC COM 92532F100 917,201 4,549,003 SH   DFND 1, 2 4,546,114 0 2,889
VERTEX INC CL A 92538J106 33,350 1,520,044 SH   DFND 1, 2 1,520,044 0 0
VICI PPTYS INC COM 925652109 1,657,458 53,431,425 SH   DFND 1, 2 53,431,425 0 0
VIR BIOTECHNOLOGY INC COM 92764N102 559,986 11,844,033 SH   DFND 1, 2 11,844,033 0 0
VISA INC COM CL A 92826C839 5,063,231 21,650,989 SH   DFND 1, 2 21,608,255 0 42,734
WASTE CONNECTIONS INC COM 94106B101 1,161,111 9,720,755 SH   DFND 1, 2 9,720,513 0 242
WASTE MGMT INC DEL COM 94106L109 296,034 2,113,129 SH   DFND 1, 2 2,113,067 0 62
WEBSTER FINL CORP CONN COM 947890109 186,149 3,489,856 SH   DFND 1, 2 3,489,856 0 0
WELLS FARGO CO NEW COM 949746101 219,861 4,854,511 SH   DFND 1, 2 4,854,511 0 0
WESTERN ALLIANCE BANCORP COM 957638109 519,573 5,595,837 SH   DFND 1, 2 5,595,837 0 0
WHIRLPOOL CORP COM 963320106 220,608 1,011,871 SH   DFND 1, 2 1,011,871 0 0
WYNN RESORTS LTD COM 983134107 1,084,381 8,866,726 SH   DFND 1, 2 8,838,175 0 28,551
XCEL ENERGY INC COM 98389B100 651,294 9,886,090 SH   DFND 1, 2 9,874,168 0 11,922
XENON PHARMACEUTICALS INC COM 98420N105 19,658 1,055,726 SH   DFND 1, 2 1,055,726 0 0
XPENG INC ADS 98422D105 52,843 1,189,621 SH   DFND 1, 2 1,189,621 0 0
YETI HLDGS INC COM 98585X104 98,552 1,073,312 SH   DFND 1, 2 1,073,312 0 0
YUM BRANDS INC COM 988498101 470,494 4,089,537 SH   DFND 1, 2 4,089,462 0 75
YUM CHINA HLDGS INC COM 98850P109 86,481 1,305,483 SH   DFND 1, 2 1,283,157 0 22,326
ZEBRA TECHNOLOGIES CORPORATI CL A 989207105 103,763 195,967 SH   DFND 1, 2 195,967 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 598,448 3,721,227 SH   DFND 1, 2 3,721,227 0 0
ZOETIS INC CL A 98978V103 63,205 339,156 SH   DFND 1, 2 339,156 0 0
ZYMERGEN INC COM 98985X100 104,014 2,599,700 SH   DFND 1, 2 2,599,700 0 0
AON PLC SHS CL A G0403H108 1,865,621 7,807,606 SH   DFND 1, 2 7,802,620 0 4,986
ARCH CAP GROUP LTD ORD G0450A105 427,099 10,968,129 SH   DFND 1, 2 10,968,129 0 0
ATLASSIAN CORP PLC CL A G06242104 243,357 943,941 SH   DFND 1, 2 943,941 0 0
ATHENE HOLDING LTD CL A G0684D107 335,223 4,966,267 SH   DFND 1, 2 4,966,267 0 0
AXALTA COATING SYS LTD COM G0750C108 42,674 1,399,600 SH   DFND 1, 2 1,399,600 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 547,634 5,641,062 SH   DFND 1, 2 5,641,062 0 0
BROOKFIELD ASSET MGMT REINS CL A EXCH LT VTG G16169107 4,544 87,353 SH   DFND 1, 2 87,335 0 18
DLOCAL LTD CLASS A COM G29018101 36,261 690,300 SH   DFND 1, 2 690,300 0 0
ESSENT GROUP LTD COM G3198U102 44,067 980,365 SH   DFND 1, 2 980,365 0 0
EVEREST RE GROUP LTD COM G3223R108 405,919 1,610,647 SH   DFND 1, 2 1,610,647 0 0
FABRINET SHS G3323L100 70,467 735,031 SH   DFND 1, 2 735,031 0 0
GENPACT LIMITED SHS G3922B107 42,386 933,000 SH   DFND 1, 2 933,000 0 0
HELEN OF TROY LTD COM G4388N106 157,116 688,744 SH   DFND 1, 2 688,744 0 0
WEATHERFORD INTL PLC ORD SHS G48833118 545 29,931 SH   DFND 1, 2 29,931 0 0
LINDE PLC SHS G5494J103 1,436,528 4,968,735 SH   DFND 1, 2 4,968,674 0 61
NORWEGIAN CRUISE LINE HLDG L SHS G66721104 222,534 7,566,594 SH   DFND 1, 2 7,566,594 0 0
NOVOCURE LTD ORD SHS G6674U108 2,028,278 9,143,742 SH   DFND 1, 2 9,137,362 0 6,380
PAGSEGURO DIGITAL LTD COM CL A G68707101 385,138 6,887,303 SH   DFND 1, 2 6,887,303 0 0
PATRIA INVESTMENTS LIMITED COM CL A G69451105 39,672 2,251,524 SH   DFND 1, 2 2,251,524 0 0
RENAISSANCERE HLDGS LTD COM G7496G103 163,058 1,095,673 SH   DFND 1, 2 1,095,673 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 694,482 16,942,708 SH   DFND 1, 2 16,942,708 0 0
CHUBB LIMITED COM H1467J104 3,551,973 22,348,408 SH   DFND 1, 2 22,325,404 0 23,004
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 743,151 4,590,921 SH   DFND 1, 2 4,584,544 0 6,377
UBS GROUP AG SHS H42097107 707,535 46,222,902 SH   DFND 1, 2 46,222,902 0 0
GLOBANT S A COM L44385109 97,104 443,031 SH   DFND 1, 2 443,031 0 0
NEXA RES S A COM L67359106 48,488 5,528,826 SH   DFND 1, 2 5,528,826 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 25,461 92,386 SH   DFND 1, 2 92,386 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210 3,523,068 5,090,260 SH   DFND 1, 2 5,077,389 0 12,871
ELASTIC N V ORD SHS N14506104 366,026 2,511,152 SH   DFND 1, 2 2,511,152 0 0
LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 4,114,011 39,992,846 SH   DFND 1, 2 39,953,913 0 38,933
YANDEX N V SHS CLASS A N97284108 839,645 11,868,033 SH   DFND 1, 2 11,840,749 0 27,284
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109 39,127 1,302,061 SH   DFND 1, 2 1,302,061 0 0
ROYAL CARIBBEAN GROUP COM V7780T103 1,783,114 20,912,689 SH   DFND 1, 2 20,896,668 0 16,021
FLEX LTD ORD Y2573F102 386,554 21,631,437 SH   DFND 1, 2 21,631,437 0 0