The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109 152,118 776,825 SH   DFND   0 0 776,825
1LIFE HEALTHCARE INC COM 68269G107 192,930 5,835,742 SH   DFND   0 0 5,835,742
1STDIBS COM INC COM 320551104 4,544 130,550 SH   DFND   0 0 130,550
2U INC COM 90214J101 4,994 119,855 SH   DFND   0 0 119,855
ABIOMED INC COM 003654100 52,731 168,950 SH   DFND   0 0 168,950
ACCEL ENTERTAINMENT INC COM CL A1 00436Q106 28 2,400 SH   DFND   0 0 2,400
ACCOLADE INC COM 00437E102 57,730 1,062,974 SH   DFND   0 0 1,062,974
ACTIVISION BLIZZARD INC COM 00507V109 2,151 22,539 SH   DFND   0 0 22,539
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 83,762 2,049,963 SH   DFND   0 0 2,049,963
ADOBE SYSTEMS INCORPORATED COM 00724F101 67,199 114,744 SH   DFND   0 0 114,744
ADYEN NV 144A COMMONSTOCK N3501V104 71,400 29,220 SH   DFND   0 0 29,220
AFFIRM HLDGS INC COM CL A 00827B106 162,909 2,418,842 SH   DFND   0 0 2,418,842
AFYA LTD CL A COM G01125106 5,017 194,618 SH   DFND   0 0 194,618
AGORA INC ADS 00851L103 57,718 1,375,554 SH   DFND   0 0 1,375,554
AIRBNB INC COM CL A 009066101 30,509 199,222 SH   DFND   0 0 199,222
ALAMOS GOLD INC NEW COM CL A 011532108 3,947 515,937 SH   DFND   0 0 515,937
ALECTOR INC COM 014442107 18,163 871,959 SH   DFND   0 0 871,959
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 313 1,382 SH   DFND   0 0 1,382
ALLAKOS INC COM 01671P100 1,480 17,341 SH   DFND   0 0 17,341
ALLOGENE THERAPEUTICS INC COM 019770106 1 29 SH   DFND   0 0 29
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 156,929 925,726 SH   DFND   0 0 925,726
ALPHABET INC CAP STK CL A 02079K305 94,957 38,888 SH   DFND   0 0 38,888
ALPHABET INC CAP STK CL C 02079K107 133,332 53,198 SH   DFND   0 0 53,198
ALPHAWAVE IP GROUP PLC ORD GBP1 ISIN GB00BNDRMJ14 SEDOL BNDRMJ COMMONSTOCK G03355107 850 171,008 SH   DFND   0 0 171,008
ALTERYX INC COM CL A 02156B103 3 30 SH   DFND   0 0 30
ALTIMETER GROWTH CORP CL A G0370L108 390 33,315 SH   DFND   0 0 33,315
AMAZON COM INC COM 023135106 512,937 149,103 SH   DFND   0 0 149,103
AMBARELLA INC SHS G037AX101 1,995 18,710 SH   DFND   0 0 18,710
AMC ENTMT HLDGS INC CL A COM 00165C104 1 18 SH   DFND   0 0 18
AMERICAN TOWER CORP NEW COM 03027X100 20,441 75,667 SH   DFND   0 0 75,667
AMERICAN WELL CORP CL A 03044L105 0 11 SH   DFND   0 0 11
ANAPLAN INC COM 03272L108 2 41 SH   DFND   0 0 41
ANTERIX INC COM 03676C100 560 9,343 SH   DFND   0 0 9,343
APA CORPORATION COM 03743Q108 3,298 152,487 SH   DFND   0 0 152,487
APOLLO ENDOSURGERY INC COM 03767D108 1,283 158,336 SH   DFND   0 0 158,336
APPFOLIO INC COM CL A 03783C100 56,875 402,794 SH   DFND   0 0 402,794
APPLE INC COM 037833100 21,519 157,121 SH   DFND   0 0 157,121
APPLIED MATLS INC COM 038222105 24 168 SH   DFND   0 0 168
APPLIED OPTOELECTRONICS INC COM 03823U102 59 7,003 SH   DFND   0 0 7,003
ARCTOS NORTHSTAR ACQUIS CORP SHS CL A G0477L100 3,924 403,325 SH   DFND   0 0 403,325
ARCUS BIOSCIENCES INC COM 03969F109 8,158 297,088 SH   DFND   0 0 297,088
ARENA PHARMACEUTICALS INC COM NEW 040047607 42,268 619,764 SH   DFND   0 0 619,764
ARGENX SE SPONSORED ADR 04016X101 39,940 132,661 SH   DFND   0 0 132,661
ARISTA NETWORKS INC COM 040413106 10,552 29,123 SH   DFND   0 0 29,123
ARITZIA INC SUB VTG SHS ISIN CA04045U1021 SEDOL BDCG2C2 COMMONSTOCK 04045U102 21,879 730,650 SH   DFND   0 0 730,650
ARLO TECHNOLOGIES INC COM 04206A101 954 140,918 SH   DFND   0 0 140,918
ARVINAS INC COM 04335A105 118,649 1,540,891 SH   DFND   0 0 1,540,891
ASANA INC CL A 04342Y104 175,286 2,825,825 SH   DFND   0 0 2,825,825
ASHTEAD GROUP ORD GBP010 ISIN GB0000536739 SEDOL 0053673 COMMONSTOCK G05320109 6 85 SH   DFND   0 0 85
AST SPACEMOBILE INC COM CL A 00217D100 986 76,190 SH   DFND   0 0 76,190
ATAI LIFE SCIENCES NV SHS N0731H103 8,091 437,373 SH   DFND   0 0 437,373
ATLASSIAN CORP PLC CL A G06242104 48,709 189,633 SH   DFND   0 0 189,633
ATRICURE INC COM 04963C209 3 42 SH   DFND   0 0 42
AURINIA PHARMACEUTICALS INC COM 05156V102 2,470 190,565 SH   DFND   0 0 190,565
AUSTERLITZ ACQUISITION CORP COM CL A G0633U101 7,946 816,643 SH   DFND   0 0 816,643
AUSTERLITZ ACQUISITION CORP SHS CL A G0633D109 6,614 666,723 SH   DFND   0 0 666,723
AUTODESK INC COM 052769106 9,237 31,646 SH   DFND   0 0 31,646
AVID TECHNOLOGY INC COM 05367P100 82,112 2,097,364 SH   DFND   0 0 2,097,364
AVIDITY BIOSCIENCES INC COM 05370A108 360 14,570 SH   DFND   0 0 14,570
AXIS BANK LIMITED GDR REG S ISIN US05462W1099 SEDOL B06CDW2 COMMONSTOCK 05462W109 3,233 64,275 SH   DFND   0 0 64,275
AYR WELLNESS INC SUB LTD VTG SHS ISIN CA05475P1099 SEDOL BNNQQ COMMONSTOCK 05475P109 12,606 441,839 SH   DFND   0 0 441,839
AZEK CO INC CL A 05478C105 64,573 1,520,804 SH   DFND   0 0 1,520,804
AZUL S A SPONSR ADR PFD 05501U106 32,058 1,214,331 SH   DFND   0 0 1,214,331
BAMBUSER AB NPV ISIN SE0009663834 SEDOL BD8Z3Y2 COMMONSTOCK W1R91S102 14,365 7,707,333 SH   DFND   0 0 7,707,333
BARCLAYS BANK PLC IPTH SR B S&P 06747R477 242 8,218 SH   DFND   0 0 8,218
BASICFIT NV 144A REG S ISIN NL0011872650 SEDOL BD9Y9B7 COMMONSTOCK N10058100 26 597 SH   DFND   0 0 597
BEACON ROOFING SUPPLY INC COM 073685109 13,227 248,391 SH   DFND   0 0 248,391
BEAM THERAPEUTICS INC COM 07373V105 18,562 144,219 SH   DFND   0 0 144,219
BERKLEY W R CORP COM 084423102 6,049 81,274 SH   DFND   0 0 81,274
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 1,431 5,149 SH   DFND   0 0 5,149
BEYOND MEAT INC COM 08862E109 106,085 673,596 SH   DFND   0 0 673,596
BIOCRYST PHARMACEUTICALS INC COM 09058V103 4,955 313,393 SH   DFND   0 0 313,393
BIOGEN INC COM 09062X103 967 2,794 SH   DFND   0 0 2,794
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 24,293 250,238 SH   DFND   0 0 250,238
BIONANO GENOMICS INC COM 09075F107 119 16,191 SH   DFND   0 0 16,191
BIONTECH SE SPONSORED ADS 09075V102 8,276 36,965 SH   DFND   0 0 36,965
BOSTON SCIENTIFIC CORP COM 101137107 883 20,647 SH   DFND   0 0 20,647
BRIDGEBIO PHARMA INC COM 10806X102 46,206 757,973 SH   DFND   0 0 757,973
BRP GROUP INC COM CL A 05589G102 9,223 346,097 SH   DFND   0 0 346,097
BURNING ROCK BIOTECH LTD SPONSORED ADS 12233L107 20,228 686,635 SH   DFND   0 0 686,635
CALIX INC COM 13100M509 162,389 3,418,723 SH   DFND   0 0 3,418,723
CAPITOL INVESTMENT CORP V COM CL A 14064F100 8,856 888,302 SH   DFND   0 0 888,302
CARL ZEISS MEDITEC AG NPV ISIN DE0005313704 SEDOL 5922961 COMMONSTOCK D14895102 2,287 11,833 SH   DFND   0 0 11,833
CARPARTS COM INC COM 14427M107 41,687 2,047,500 SH   DFND   0 0 2,047,500
CARVANA CO CL A 146869102 361,007 1,196,101 SH   DFND   0 0 1,196,101
CATAPULT GROUP INTERNATIONAL ISIN AU000000CAT9 SEDOL BTL0Y76 COMMONSTOCK Q2159P101 246 164,000 SH   DFND   0 0 164,000
CELLNEX TELECOM SAU EUR025 144A REG S ISIN ES0105066007 SEDOL COMMONSTOCK E2R41M104 5,225 82,013 SH   DFND   0 0 82,013
CELSIUS HLDGS INC COM NEW 15118V207 13,810 181,499 SH   DFND   0 0 181,499
CHARLES RIV LABS INTL INC COM 159864107 8,473 22,904 SH   DFND   0 0 22,904
CHART INDS INC COM 16115Q308 86 588 SH   DFND   0 0 588
CHEGG INC COM 163092109 139,825 1,682,412 SH   DFND   0 0 1,682,412
CHEWY INC CL A 16679L109 36,872 462,571 SH   DFND   0 0 462,571
CHIPOTLE MEXICAN GRILL INC COM 169656105 36 23 SH   DFND   0 0 23
CHUBB LIMITED COM H1467J104 18,991 119,488 SH   DFND   0 0 119,488
CITIGROUP INC COM NEW 172967424 2 35 SH   DFND   0 0 35
CLASS ACCELERATION CORP COM 18274B106 12,006 1,239,003 SH   DFND   0 0 1,239,003
CLEAR SECURE INC COM CL A 18467V109 611 15,264 SH   DFND   0 0 15,264
CLEARFIELD INC COM 18482P103 2,934 78,333 SH   DFND   0 0 78,333
CLOUDFLARE INC CL A COM 18915M107 509,115 4,810,232 SH   DFND   0 0 4,810,232
CM LIFE SCIENCES II INC CL A 125842104 882 71,938 SH   DFND   0 0 71,938
CM LIFE SCIENCES III INC CLASS A COM 125841106 8,351 809,212 SH   DFND   0 0 809,212
CODEXIS INC COM 192005106 55,397 2,444,717 SH   DFND   0 0 2,444,717
COINBASE GLOBAL INC COM CL A 19260Q107 27,839 109,907 SH   DFND   0 0 109,907
COMMSCOPE HLDG CO INC COM 20337X109 12,434 583,488 SH   DFND   0 0 583,488
COMPASS INC CL A 20464U100 4,690 356,911 SH   DFND   0 0 356,911
CONFLUENT INC CLASS A COM 20717M103 126,066 2,654,024 SH   DFND   0 0 2,654,024
CONTROLADORA VUELA COMP DE A SPON ADR RP 10 21240E105 94,064 4,896,638 SH   DFND   0 0 4,896,638
CORECIVIC INC COM 21871N101 85 8,079 SH   DFND   0 0 8,079
COUPA SOFTWARE INC COM 22266L106 21,968 83,811 SH   DFND   0 0 83,811
COUPANG INC CL A 22266T109 11,306 270,340 SH   DFND   0 0 270,340
COVETRUS INC COM 22304C100 0 8 SH   DFND   0 0 8
CREE INC COM 225447101 1,615 16,491 SH   DFND   0 0 16,491
CROWDSTRIKE HLDGS INC CL A 22788C105 60,620 241,218 SH   DFND   0 0 241,218
CUSTOM TRUCK ONE SOURCE INC COM CL A 23204X103 21,245 2,231,567 SH   DFND   0 0 2,231,567
CVRX INC COM 126638105 21,277 759,902 SH   DFND   0 0 759,902
D R HORTON INC COM 23331A109 4,539 50,225 SH   DFND   0 0 50,225
DATADOG INC CL A COM 23804L103 11,568 111,146 SH   DFND   0 0 111,146
DECARBONIZATION PLUS ACQU II CLASS A COM 24279D105 4,212 406,152 SH   DFND   0 0 406,152
DEERE & CO COM 244199105 47,095 133,524 SH   DFND   0 0 133,524
DENALI THERAPEUTICS INC COM 24823R105 222,435 2,835,733 SH   DFND   0 0 2,835,733
DENBURY INC COM 24790A101 46,492 605,528 SH   DFND   0 0 605,528
DERMTECH INC COM 24984K105 2,736 65,828 SH   DFND   0 0 65,828
DEXCOM INC COM 252131107 92,151 215,811 SH   DFND   0 0 215,811
DICKS SPORTING GOODS INC COM 253393102 97,663 974,777 SH   DFND   0 0 974,777
DISH NETWORK CORPORATION CL A 25470M109 38,585 923,093 SH   DFND   0 0 923,093
DISNEY WALT CO COM 254687106 16,037 91,238 SH   DFND   0 0 91,238
DIVERSIFIED ENERGY COMPANY PLC ORD GBP001 ISIN GB00BYX7JT74 SE COMMONSTOCK G2891G105 10,483 7,213,478 SH   DFND   0 0 7,213,478
DOCUSIGN INC COM 256163106 367,550 1,314,697 SH   DFND   0 0 1,314,697
DOWNEY FINL CORP COMMONSTOCK 261018105 0 200 SH   DFND   0 0 200
DRAFTKINGS INC COM CL A 26142R104 1,635 31,338 SH   DFND   0 0 31,338
DRAGONEER GROWTH OPPORTUN CO COM CL A G28302100 902 90,588 SH   DFND   0 0 90,588
DUCK CREEK TECHNOLOGIES INC SHS 264120106 5,241 120,458 SH   DFND   0 0 120,458
EARGO INC COM 270087109 7,317 183,347 SH   DFND   0 0 183,347
ENDEAVOUR MINING PLC ORD USD001 ISIN GB00BL6K5J42 SEDOL BN7KJ COMMONSTOCK G3042J105 7,259 337,684 SH   DFND   0 0 337,684
ENPHASE ENERGY INC COM 29355A107 238,168 1,297,001 SH   DFND   0 0 1,297,001
EPAM SYS INC COM 29414B104 176,039 344,525 SH   DFND   0 0 344,525
EQUATOR EXPLORATION COM STK NPV COMMONSTOCK G3084F128 0 215,000 SH   DFND   0 0 215,000
ESPERION THERAPEUTICS INC NE COM 29664W105 21 1,006 SH   DFND   0 0 1,006
ETSY INC COM 29786A106 70,904 344,461 SH   DFND   0 0 344,461
EVENTBRITE INC COM CL A 29975E109 1,997 105,116 SH   DFND   0 0 105,116
EVEREST RE GROUP LTD COM G3223R108 4,131 16,393 SH   DFND   0 0 16,393
EVERI HLDGS INC COM 30034T103 53,846 2,159,041 SH   DFND   0 0 2,159,041
EXACT SCIENCES CORP COM 30063P105 179,675 1,445,378 SH   DFND   0 0 1,445,378
FACEBOOK INC CL A 30303M102 45,181 129,940 SH   DFND   0 0 129,940
FARFETCH LTD ORD SH CL A 30744W107 5,530 109,807 SH   DFND   0 0 109,807
FATHOM HOLDINGS INC COM 31189V109 14,084 429,517 SH   DFND   0 0 429,517
FERGUSON PLC ORD GBP010 ISIN JE00BJVNSS43 SEDOL BJVNSS4 COMMONSTOCK ZZDKWOTT6 14,878 107,163 SH   DFND   0 0 107,163
FG NEW AMER ACQUISITION CORP COM 30259V106 14,945 1,463,723 SH   DFND   0 0 1,463,723
FIGS INC CL A 30260D103 16,668 332,691 SH   DFND   0 0 332,691
FIVERR INTL LTD ORD SHS M4R82T106 1,252 5,162 SH   DFND   0 0 5,162
FLOOR & DECOR HLDGS INC CL A 339750101 123,236 1,165,902 SH   DFND   0 0 1,165,902
FLUIDRA SA EUR1 ISIN ES0137650018 SEDOL B28V440 COMMONSTOCK E52619108 30,712 774,231 SH   DFND   0 0 774,231
FLYWIRE CORPORATION COM VTG 302492103 3,074 83,660 SH   DFND   0 0 83,660
FORD MTR CO DEL COM 345370860 1,805 121,444 SH   DFND   0 0 121,444
FOREST ROAD ACQUISITION COR CL A 34619V103 7,091 723,542 SH   DFND   0 0 723,542
FRANCO NEV CORP COM 351858105 10,379 71,543 SH   DFND   0 0 71,543
FRANKLIN COVEY CO COM 353469109 2 62 SH   DFND   0 0 62
FRESHPET INC COM 358039105 266,589 1,635,917 SH   DFND   0 0 1,635,917
FRIENDLY ENERGY EXPLORATION COM NPV COMMONSTOCK 35846A200 0 690 SH   DFND   0 0 690
FRONTIER GROUP HLDGS INC COM 35909R108 6,256 367,135 SH   DFND   0 0 367,135
GAIA INC NEW CL A 36269P104 2 177 SH   DFND   0 0 177
GALAPAGOS NV NPV ISIN BE0003818359 SEDOL B07Q2V5 COMMONSTOCK B44170106 19,036 274,487 SH   DFND   0 0 274,487
GARRETT MOTION INC COM 366505105 10,575 1,325,168 SH   DFND   0 0 1,325,168
GEOPARK LTD USD SHS G38327105 4,649 367,545 SH   DFND   0 0 367,545
GLADSTONE LD CORP COM 376549101 1 40 SH   DFND   0 0 40
GLAUKOS CORP COM 377322102 71,041 837,449 SH   DFND   0 0 837,449
GLOBANT S A COM L44385109 75,950 346,519 SH   DFND   0 0 346,519
GOGOLD RES INC COM ISIN CA38045Y1025 SEDOL B60BNP0 COMMONSTOCK 38045Y102 2,482 997,996 SH   DFND   0 0 997,996
GOLDEN MINERALS CO COM 381119106 29 46,847 SH   DFND   0 0 46,847
GOLDMAN SACHS GROUP INC COM 38141G104 109 287 SH   DFND   0 0 287
GREEN THUMB INDUSTRIES INC COM ISIN CA39342L1085 SEDOL BGDQBQ9 COMMONSTOCK 39342L108 30,567 924,991 SH   DFND   0 0 924,991
GROCERY OUTLET HLDG CORP COM 39874R101 9 261 SH   DFND   0 0 261
GUARDANT HEALTH INC COM 40131M109 764 6,149 SH   DFND   0 0 6,149
H & E EQUIPMENT SERVICES INC COM 404030108 4,380 131,647 SH   DFND   0 0 131,647
HDFC BANK LTD SPONSORED ADS 40415F101 12,049 164,790 SH   DFND   0 0 164,790
HEALTHSTREAM INC COM 42222N103 10,950 391,920 SH   DFND   0 0 391,920
HEARUSA INC NEW COMMONSTOCK 422360305 0 375 SH   DFND   0 0 375
HEICO CORP NEW CL A 422806208 12,385 99,731 SH   DFND   0 0 99,731
HEICO CORP NEW COM 422806109 2,572 18,448 SH   DFND   0 0 18,448
HELLOFRESH SE ISIN DE000A161408 SEDOL BYWH8S0 COMMONSTOCK D3R2MA100 60,213 619,349 SH   DFND   0 0 619,349
HONEST CO INC COM 438333106 87,937 5,431,565 SH   DFND   0 0 5,431,565
HOUGHTON MIFFLIN HARCOURT CO COM 44157R109 1,334 120,861 SH   DFND   0 0 120,861
HUBSPOT INC COM 443573100 305,545 524,343 SH   DFND   0 0 524,343
ICICI BANK LIMITED ADR 45104G104 9,173 536,449 SH   DFND   0 0 536,449
IDEXX LABS INC COM 45168D104 5,996 9,494 SH   DFND   0 0 9,494
ILLUMINA INC COM 452327109 3,212 6,788 SH   DFND   0 0 6,788
IMPINJ INC COM 453204109 51,743 1,002,965 SH   DFND   0 0 1,002,965
INARI MED INC COM 45332Y109 20,827 223,277 SH   DFND   0 0 223,277
INFINERA CORP COM 45667G103 131,037 12,846,766 SH   DFND   0 0 12,846,766
INSPIRE MED SYS INC COM 457730109 149,963 775,966 SH   DFND   0 0 775,966
INSULET CORP COM 45784P101 4,664 16,992 SH   DFND   0 0 16,992
INTERBREW PLC GDREACH REPR 1 A SH REG S COMMONSTOCK 45845T308 0 200 SH   DFND   0 0 200
INTL GNRL INSURANCE HLDNGS L SHS G4809J106 20,711 2,226,980 SH   DFND   0 0 2,226,980
INTUITIVE SURGICAL INC COM NEW 46120E602 151,426 164,658 SH   DFND   0 0 164,658
INVITAE CORP COM 46185L103 228,910 6,786,549 SH   DFND   0 0 6,786,549
IRHYTHM TECHNOLOGIES INC COM 450056106 0 4 SH   DFND   0 0 4
IROBOT CORP COM 462726100 9 100 SH   DFND   0 0 100
JAMF HLDG CORP COM 47074L105 6,536 194,692 SH   DFND   0 0 194,692
JPMORGAN CHASE & CO COM 46625H100 2,469 15,874 SH   DFND   0 0 15,874
JUST EAT TAKEAWAYCOM NV EUR004 144A REG S ISIN NL0012015705 COMMONSTOCK ZZDLN2RN7 783 8,465 SH   DFND   0 0 8,465
KADMON HLDGS INC COM 48283N106 1,901 491,136 SH   DFND   0 0 491,136
KAMBI GROUP PLC EUR0003 ISIN MT0000780107 SEDOL BMNQDC1 COMMONSTOCK X4170A107 68 1,367 SH   DFND   0 0 1,367
KB HOME COM 48666K109 378 9,272 SH   DFND   0 0 9,272
KINSALE CAP GROUP INC COM 49714P108 340 2,062 SH   DFND   0 0 2,062
KIRKLAND LAKE GOLD LTD COM 49741E100 5,604 145,435 SH   DFND   0 0 145,435
KORN FERRY COM NEW 500643200 2 28 SH   DFND   0 0 28
KORNIT DIGITAL LTD SHS M6372Q113 211,444 1,700,665 SH   DFND   0 0 1,700,665
KYMERA THERAPEUTICS INC COM 501575104 5,266 108,578 SH   DFND   0 0 108,578
LEMONADE INC COM 52567D107 10,761 98,358 SH   DFND   0 0 98,358
LESLIES INC COM 527064109 26,560 966,186 SH   DFND   0 0 966,186
LGI HOMES INC COM 50187T106 57,849 357,222 SH   DFND   0 0 357,222
LI NING CO LTD HKD01 ISIN KYG5496K1242 SEDOL B01JCK9 COMMONSTOCK G5496K124 72 5,860 SH   DFND   0 0 5,860
LIBERTY MEDIA CORP DEL COM A BRAVES GRP 531229706 2,706 95,879 SH   DFND   0 0 95,879
LIBERTY MEDIA CORP DEL COM C BRAVES GRP 531229888 5,936 213,767 SH   DFND   0 0 213,767
LIBERTY MEDIA CORP DEL COM SER C FRMLA 531229854 1,911 39,641 SH   DFND   0 0 39,641
LINDBLAD EXPEDITIONS HLDGS I COM 535219109 33,315 2,080,862 SH   DFND   0 0 2,080,862
LIVE NATION ENTERTAINMENT IN COM 538034109 31 356 SH   DFND   0 0 356
LIVE OAK BANCSHARES INC COM 53803X105 2 33 SH   DFND   0 0 33
LORAL SPACE & COM INC COM 543881106 23,763 611,658 SH   DFND   0 0 611,658
LOVESAC COMPANY COM 54738L109 2,242 28,095 SH   DFND   0 0 28,095
LULULEMON ATHLETICA INC COM 550021109 8,095 22,181 SH   DFND   0 0 22,181
LUMINAR TECHNOLOGIES INC COM CL A 550424105 6,425 292,713 SH   DFND   0 0 292,713
LYFT INC CL A COM 55087P104 3,210 53,072 SH   DFND   0 0 53,072
MAG SILVER CORP COM 55903Q104 31,782 1,519,213 SH   DFND   0 0 1,519,213
MAGENTA THERAPEUTICS INC COM 55910K108 40,123 4,102,517 SH   DFND   0 0 4,102,517
MAGNOLIA OIL & GAS CORP CL A 559663109 14,222 909,924 SH   DFND   0 0 909,924
MAKO MINING CORP COM NPV ISIN CA56089A1030 SEDOL BFXPTG5 COMMONSTOCK 56089A103 973 3,130,445 SH   DFND   0 0 3,130,445
MARQETA INC CLASS A COM 57142B104 10,805 384,919 SH   DFND   0 0 384,919
MARTIN MARIETTA MATLS INC COM 573284106 31,066 88,302 SH   DFND   0 0 88,302
MASTEC INC COM 576323109 4,336 40,870 SH   DFND   0 0 40,870
MASTERCARD INCORPORATED CL A 57636Q104 27,741 75,984 SH   DFND   0 0 75,984
MATCH GROUP INC NEW COM 57667L107 18,074 112,087 SH   DFND   0 0 112,087
MAXAR TECHNOLOGIES INC COM 57778K105 54,794 1,372,596 SH   DFND   0 0 1,372,596
MERCADOLIBRE INC COM 58733R102 206,562 132,599 SH   DFND   0 0 132,599
MGP INGREDIENTS INC NEW COM 55303J106 1,584 23,417 SH   DFND   0 0 23,417
MICROSOFT CORP COM 594918104 81,590 301,180 SH   DFND   0 0 301,180
MIROMATRIX MED INC COM 60471P108 1,864 160,000 SH   DFND   0 0 160,000
MODERNA INC COM 60770K107 231 982 SH   DFND   0 0 982
MONDAY COM LTD SHS M7S64H106 33,600 150,275 SH   DFND   0 0 150,275
MONEYGRAM INTL INC COM NEW 60935Y208 5,707 566,173 SH   DFND   0 0 566,173
MONGODB INC CL A 60937P106 242,211 669,980 SH   DFND   0 0 669,980
MONOLITHIC PWR SYS INC COM 609839105 16,370 43,835 SH   DFND   0 0 43,835
NAKED WINES PLC ORD GBP0075 ISIN GB00B021F836 SEDOL B021F83 COMMONSTOCK G6361W102 9,736 873,313 SH   DFND   0 0 873,313
NATERA INC COM 632307104 176,454 1,554,246 SH   DFND   0 0 1,554,246
NATIONAL VISION HLDGS INC COM 63845R107 38 734 SH   DFND   0 0 734
NEOPHOTONICS CORP COM 64051T100 1,877 183,866 SH   DFND   0 0 183,866
NETCOMPANY GROUP AS DKK1 144A ISIN DK0060952919 SEDOL BFYDWS1 COMMONSTOCK K7020C102 110,488 972,383 SH   DFND   0 0 972,383
NETFLIX INC COM 64110L106 519,049 982,657 SH   DFND   0 0 982,657
NEVRO CORP COM 64157F103 1,623 9,790 SH   DFND   0 0 9,790
NEW PAC METALS CORP COM 64782A107 9,382 1,934,416 SH   DFND   0 0 1,934,416
NEW VISTA ACQUISITION CORP CL A SHS G6529L105 8,743 904,127 SH   DFND   0 0 904,127
NEW VISTA ACQUISITION CORP UNIT 02/01/2026 G6529L113 11,678 1,167,816 SH   DFND   0 0 1,167,816
NEW YORK TIMES CO CL A 650111107 116,370 2,672,100 SH   DFND   0 0 2,672,100
NIKE INC CL B 654106103 25,291 163,706 SH   DFND   0 0 163,706
NIU TECHNOLOGIES ADS 65481N100 21 635 SH   DFND   0 0 635
NV5 GLOBAL INC COM 62945V109 61 644 SH   DFND   0 0 644
NVIDIA CORPORATION COM 67066G104 180,001 224,973 SH   DFND   0 0 224,973
NYXOAH SA NPV ISIN BE0974358906 SEDOL BN782G7 COMMONSTOCK B6S7WD106 5,752 190,951 SH   DFND   0 0 190,951
OAK STR HEALTH INC COM 67181A107 76,146 1,300,089 SH   DFND   0 0 1,300,089
OATLY GROUP AB SPONSORED ADS 67421J108 619 25,299 SH   DFND   0 0 25,299
OCADO GROUP PLC ORD GBP002 ISIN GB00B3MBS747 SEDOL B3MBS74 COMMONSTOCK G6718L106 281,380 10,168,975 SH   DFND   0 0 10,168,975
OKTA INC CL A 679295105 274,367 1,121,330 SH   DFND   0 0 1,121,330
OLINK HLDG AB SPONSORED ADS 680710100 1,100 31,968 SH   DFND   0 0 31,968
OLO INC CL A 68134L109 630 16,845 SH   DFND   0 0 16,845
ONEWATER MARINE INC CL A COM 68280L101 41,833 995,311 SH   DFND   0 0 995,311
OPTION CARE HEALTH INC COM NEW 68404L201 38,182 1,745,877 SH   DFND   0 0 1,745,877
OUTSET MED INC COM 690145107 3,466 69,356 SH   DFND   0 0 69,356
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 708 20,237 SH   DFND   0 0 20,237
PALOMAR HLDGS INC COM 69753M105 9,411 124,721 SH   DFND   0 0 124,721
PAYPAL HLDGS INC COM 70450Y103 57,016 195,608 SH   DFND   0 0 195,608
PELOTON INTERACTIVE INC CL A COM 70614W100 403,642 3,254,655 SH   DFND   0 0 3,254,655
PENN NATL GAMING INC COM 707569109 44,211 578,000 SH   DFND   0 0 578,000
PENN TREATY AMERN CORP COM NEW COMMONSTOCK 707874400 0 125 SH   DFND   0 0 125
PENSKE AUTOMOTIVE GRP INC COM 70959W103 4,362 57,781 SH   DFND   0 0 57,781
PHATHOM PHARMACEUTICALS INC COM 71722W107 18,500 546,522 SH   DFND   0 0 546,522
PINDUODUO INC SPONSORED ADS 722304102 4,447 35,007 SH   DFND   0 0 35,007
PINTEREST INC CL A 72352L106 99,403 1,259,059 SH   DFND   0 0 1,259,059
PONTEM CORPORATION SHS CL A G71707106 4,786 492,338 SH   DFND   0 0 492,338
POOL CORP COM 73278L105 144,656 315,389 SH   DFND   0 0 315,389
POSHMARK INC COM CL A 73739W104 1,708 35,773 SH   DFND   0 0 35,773
PRIMORIS SVCS CORP COM 74164F103 2,975 101,096 SH   DFND   0 0 101,096
PROCORE TECHNOLOGIES INC COM 74275K108 254,063 2,675,759 SH   DFND   0 0 2,675,759
PROFOUND MED CORP COM NEW 74319B502 3,217 196,642 SH   DFND   0 0 196,642
PROQR THRAPEUTICS N V SHS EURO N71542109 3,496 518,733 SH   DFND   0 0 518,733
PROVENTION BIO INC COM 74374N102 2,428 288,070 SH   DFND   0 0 288,070
PULMONX CORP COM 745848101 46,136 1,045,702 SH   DFND   0 0 1,045,702
PURECYCLE TECHNOLOGIES INC COM 74623V103 423 17,872 SH   DFND   0 0 17,872
PURPLE INNOVATION INC COM 74640Y106 40,439 1,531,183 SH   DFND   0 0 1,531,183
Q2 HLDGS INC COM 74736L109 26,151 254,937 SH   DFND   0 0 254,937
QORVO INC COM 74736K101 6,962 35,586 SH   DFND   0 0 35,586
QUALTRICS INTL INC COM CL A 747601201 6,174 161,411 SH   DFND   0 0 161,411
QUANTA SVCS INC COM 74762E102 16,575 183,003 SH   DFND   0 0 183,003
QUANTERIX CORP COM 74766Q101 169,618 2,891,539 SH   DFND   0 0 2,891,539
REDFIN CORP COM 75737F108 41,123 648,523 SH   DFND   0 0 648,523
RELAY THERAPEUTICS INC COM 75943R102 30,572 835,538 SH   DFND   0 0 835,538
RENALYTIX PLC ADS 75973T101 100,820 3,267,018 SH   DFND   0 0 3,267,018
RENALYTIX PLC ORDINARY SHARES ISIN GB00BYWL4Y04 SEDOL BYWL4Y0 COMMONSTOCK G7489R108 1,006 67,405 SH   DFND   0 0 67,405
REPARE THERAPEUTICS INC COM 760273102 101 3,233 SH   DFND   0 0 3,233
REPLIGEN CORP COM 759916109 93,023 466,001 SH   DFND   0 0 466,001
REYNA SILVER CORP COM NPV ISIN CA76170Q1063 SEDOL BMG11D0 COMMONSTOCK 76170Q106 1,639 2,305,817 SH   DFND   0 0 2,305,817
RHYTHM PHARMACEUTICALS INC COM 76243J105 29,157 1,489,123 SH   DFND   0 0 1,489,123
RICE ACQUISITION CORP COM CL A 762594109 18,673 1,034,536 SH   DFND   0 0 1,034,536
RIGHTMOVE ORD GBP0001 ISIN GB00BGDT3G23 SEDOL BGDT3G2 COMMONSTOCK G7565D106 7,555 842,113 SH   DFND   0 0 842,113
RINGCENTRAL INC CL A 76680R206 129,377 445,238 SH   DFND   0 0 445,238
ROBLOX CORP CL A 771049103 2,584 28,721 SH   DFND   0 0 28,721
RODGERS SILICON VALLEY AQ CO COM 774873103 50,934 2,217,417 SH   DFND   0 0 2,217,417
RODGERS SILICON VALLEY AQ CO UNIT 11/30/2025 774873202 20,668 743,463 SH   DFND   0 0 743,463
ROKU INC COM CL A 77543R102 755,306 1,644,652 SH   DFND   0 0 1,644,652
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 4,088 99,740 SH   DFND   0 0 99,740
SAFARICOM PLC KES005 ISIN KE1000001402 SEDOL B2QN3J6 COMMONSTOCK V74587102 34,495 89,795,905 SH   DFND   0 0 89,795,905
SAFETY INS GROUP INC COM 78648T100 99 1,269 SH   DFND   0 0 1,269
SALESFORCE COM INC COM 79466L302 39,726 162,632 SH   DFND   0 0 162,632
SANA BIOTECHNOLOGY INC COM 799566104 7,912 402,419 SH   DFND   0 0 402,419
SAREPTA THERAPEUTICS INC COM 803607100 626 8,047 SH   DFND   0 0 8,047
SCHRODINGER INC COM 80810D103 50,626 669,573 SH   DFND   0 0 669,573
SCIENTIFIC GAMES CORP COM 80874P109 840 10,846 SH   DFND   0 0 10,846
SCOTTS MIRACLE-GRO CO CL A 810186106 73,624 383,620 SH   DFND   0 0 383,620
SEA LTD SPONSORD ADS 81141R100 2 7 SH   DFND   0 0 7
SEMLER SCIENTIFIC INC COM USD0001 COMMONSTOCK 81684M104 6,189 55,364 SH   DFND   0 0 55,364
SENESTECH INC COM NEW 81720R208 48 30,022 SH   DFND   0 0 30,022
SENSEONICS HLDGS INC COM 81727U105 17,028 4,434,298 SH   DFND   0 0 4,434,298
SENTINELONE INC CL A 81730H109 1,488 35,000 SH   DFND   0 0 35,000
SERES THERAPEUTICS INC COM 81750R102 57,404 2,406,885 SH   DFND   0 0 2,406,885
SERVICENOW INC COM 81762P102 49,883 90,771 SH   DFND   0 0 90,771
SHAKE SHACK INC CL A 819047101 310,268 2,899,161 SH   DFND   0 0 2,899,161
SHERWIN WILLIAMS CO COM 824348106 1,426 5,234 SH   DFND   0 0 5,234
SHOALS TECHNOLOGIES GROUP IN CL A 82489W107 3,476 97,916 SH   DFND   0 0 97,916
SHOCKWAVE MED INC COM 82489T104 284,795 1,501,053 SH   DFND   0 0 1,501,053
SHOP APOTHEKE EUROPE NV NPV 144A REG S ISIN NL0012044747 SEDOL COMMONSTOCK N7975Z103 56,408 300,288 SH   DFND   0 0 300,288
SHOPIFY INC CL A 82509L107 570,885 390,755 SH   DFND   0 0 390,755
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SI-BONE INC COM 825704109 69,141 2,197,046 SH   DFND   0 0 2,197,046
SIGILON THERAPEUTICS INC COM 82657L107 909 84,699 SH   DFND   0 0 84,699
SILK RD MED INC COM 82710M100 300 6,261 SH   DFND   0 0 6,261
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SIMILARWEB LTD SHS M84137104 236 12,000 SH   DFND   0 0 12,000
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SITEONE LANDSCAPE SUPPLY INC COM 82982L103 41,725 246,513 SH   DFND   0 0 246,513
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SKEENA RESOURCES COM NPVPOST REV SPLIT ISIN CA83056P7157 SEDO COMMONSTOCK 83056P715 10,240 975,405 SH   DFND   0 0 975,405
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SMARTSHEET INC COM CL A 83200N103 845 11,683 SH   DFND   0 0 11,683
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SNAP INC CL A 83304A106 236,842 3,475,814 SH   DFND   0 0 3,475,814
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SONOS INC COM 83570H108 8,776 249,111 SH   DFND   0 0 249,111
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SPOTIFY TECHNOLOGY S A SHS L8681T102 191,138 693,560 SH   DFND   0 0 693,560
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SS&C TECHNOLOGIES HLDGS INC COM 78467J100 41,904 581,510 SH   DFND   0 0 581,510
STAAR SURGICAL CO COM PAR $0.01 852312305 40 261 SH   DFND   0 0 261
STARBUCKS CORP COM 855244109 17,536 156,840 SH   DFND   0 0 156,840
STEM INC COM 85859N102 39,243 1,089,782 SH   DFND   0 0 1,089,782
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STONECO LTD COM CL A G85158106 108,663 1,620,391 SH   DFND   0 0 1,620,391
STRIDE INC COM 86333M108 2 61 SH   DFND   0 0 61
SUNNOVA ENERGY INTL INC. COM 86745K104 1,467 38,965 SH   DFND   0 0 38,965
SUNRUN INC COM 86771W105 103,379 1,853,341 SH   DFND   0 0 1,853,341
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SYNLOGIC INC COM 87166L100 5,127 1,317,925 SH   DFND   0 0 1,317,925
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TANDEM DIABETES CARE INC COM NEW 875372203 77,001 790,567 SH   DFND   0 0 790,567
TASKUS INC CLASS A COM 87652V109 342 10,000 SH   DFND   0 0 10,000
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TELADOC HEALTH INC COM 87918A105 173,066 1,040,747 SH   DFND   0 0 1,040,747
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TESLA INC COM 88160R101 975,615 1,435,361 SH   DFND   0 0 1,435,361
THE BEAUTY HEALTH COMPANY COM CL A 88331L108 17 1,000 SH   DFND   0 0 1,000
THOR INDS INC COM 885160101 5,330 47,165 SH   DFND   0 0 47,165
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UIPATH INC CL A 90364P105 32,298 475,467 SH   DFND   0 0 475,467
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 1,749 18,344 SH   DFND   0 0 18,344
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VITAL FARMS INC COM 92847W103 19,502 977,058 SH   DFND   0 0 977,058
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WHITING PETE CORP NEW COM NEW 966387508 19,070 349,596 SH   DFND   0 0 349,596
WILLOW BIOSCIENCES INC COM NPV POST REV SPLIT ISIN CA97111B40 COMMONSTOCK 97111B404 589 722,096 SH   DFND   0 0 722,096
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WIX COM LTD SHS M98068105 161 555 SH   DFND   0 0 555
WORKDAY INC CL A 98138H101 19,308 80,876 SH   DFND   0 0 80,876
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XOMETRY INC CLASS A COM 98423F109 16,789 192,121 SH   DFND   0 0 192,121
XP INC CL A G98239109 28,549 655,549 SH   DFND   0 0 655,549
ZAI LAB LTD ADR 98887Q104 187,360 1,058,589 SH   DFND   0 0 1,058,589
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ZIPRECRUITER INC CL A 98980B103 45 1,809 SH   DFND   0 0 1,809
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 331,768 857,214 SH   DFND   0 0 857,214
ZOOMINFO TECHNOLOGIES INC COM CL A 98980F104 12,386 237,422 SH   DFND   0 0 237,422
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ZUR ROSE GROUP AG CHF3000 ISIN CH0042615283 SEDOL B92M6T7 COMMONSTOCK H9875C108 57,732 150,536 SH   DFND   0 0 150,536
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