The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109 65 332 SH   DFND   0 0 332
3M CO COM 88579Y101 41 206 SH   DFND   0 0 206
908 DEVICES INC COM 65443P102 38 968 SH   DFND   0 0 968
ABBOTT LABS COM 002824100 39 333 SH   DFND   0 0 333
ABBVIE INC COM 00287Y109 39 347 SH   DFND   0 0 347
ACCELERATE DIAGNOSTICS INC COM 00430H102 17 2,079 SH   DFND   0 0 2,079
ACTIVISION BLIZZARD INC COM 00507V109 14 149 SH   DFND   0 0 149
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 38 8,892 SH   DFND   0 0 8,892
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 14 345 SH   DFND   0 0 345
ADOBE SYSTEMS INCORPORATED COM 00724F101 5,551 9,478 SH   DFND   0 0 9,478
ADVANCE AUTO PARTS INC COM 00751Y106 21 100 SH   DFND   0 0 100
AERCAP HOLDINGS NV SHS N00985106 6 123 SH   DFND   0 0 123
AEROVIRONMENT INC COM 008073108 37 373 SH   DFND   0 0 373
AFYA LTD CL A COM G01125106 464 18,000 SH   DFND   0 0 18,000
AGILENT TECHNOLOGIES INC COM 00846U101 115 779 SH   DFND   0 0 779
AGILYSYS INC COM 00847J105 42 747 SH   DFND   0 0 747
ALBERTSONS COS INC COMMON STOCK 013091103 14 709 SH   DFND   0 0 709
ALEXION PHARMACEUTICALS INC COM 015351109 115 626 SH   DFND   0 0 626
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 15,146 66,785 SH   DFND   0 0 66,785
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 101 597 SH   DFND   0 0 597
ALPHABET INC CAP STK CL A 02079K305 44,787 18,342 SH   DFND   219 0 18,123
ALPHABET INC CAP STK CL C 02079K107 10,374 4,139 SH   DFND   0 0 4,139
AMAZON COM INC COM 023135106 24,030 6,985 SH   DFND   747 0 6,238
AMBARELLA INC SHS G037AX101 46 427 SH   DFND   0 0 427
AMCOR PLC ORD G0250X107 31 2,742 SH   DFND   0 0 2,742
AMGEN INC COM 031162100 39 159 SH   DFND   0 0 159
AMKOR TECHNOLOGY INC COM 031652100 13 534 SH   DFND   0 0 534
ANTHEM INC COM 036752103 32 84 SH   DFND   0 0 84
APPLE INC COM 037833100 15,052 109,903 SH   DFND   483 0 109,420
APPLIED MATLS INC COM 038222105 32 226 SH   DFND   0 0 226
ARCO PLATFORM LTD COM CL A G04553106 2,143 69,882 SH   DFND   0 0 69,882
ARCTURUS THERAPEUTICS HLDGS COM 03969T109 41 1,205 SH   DFND   0 0 1,205
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 26 308 SH   DFND   0 0 308
ASANA INC CL A 04342Y104 62 998 SH   DFND   0 0 998
ASENSUS SURGICAL INC COM COM 04367G103 45 14,069 SH   DFND   0 0 14,069
ASTRAZENECA PLC SPONSORED ADR 046353108 1,676 27,984 SH   DFND   0 0 27,984
AUTONATION INC COM 05329W102 22 237 SH   DFND   0 0 237
BAIDU INC SPON ADR REP A 056752108 15,515 76,089 SH   DFND   0 0 76,089
BAKER HUGHES A GE CO CL A 05722G100 10 426 SH   DFND   0 0 426
BALLARD PWR SYS INC NEW COM 058586108 41 2,268 SH   DFND   0 0 2,268
BANCO BRADESCO S A SP ADR PFD NEW 059460303 8,999 1,754,147 SH   DFND   0 0 1,754,147
BANCO SANTANDER MEXICO AS SPONSORED ADS B 05969B103 615 97,853 SH   DFND   0 0 97,853
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 14 50 SH   DFND   0 0 50
BEST BUY INC COM 086516101 2,444 21,257 SH   DFND   21,257 0 0
BIGCOMMERCE HLDGS INC COM SER 1 08975P108 45 693 SH   DFND   0 0 693
BIO RAD LABS INC CL A 090572207 18 28 SH   DFND   0 0 28
BIO TECHNE CORP COM 09073M104 65 145 SH   DFND   0 0 145
BIOGEN INC COM 09062X103 50 145 SH   DFND   0 0 145
BIOMARIN PHARMACEUTICAL INC COM 09061G101 34 408 SH   DFND   0 0 408
BIT MINING LIMITED SPON ADR REP A 055474100 41 5,154 SH   DFND   0 0 5,154
BLUEPRINT MEDICINES CORP COM 09627Y109 18 210 SH   DFND   0 0 210
BOOKING HOLDINGS INC COM 09857L108 21,732 9,932 SH   DFND   0 0 9,932
BOSTON SCIENTIFIC CORP COM 101137107 44 1,024 SH   DFND   0 0 1,024
BP PLC SPONSORED ADR 055622104 1,606 60,800 SH   DFND   0 0 60,800
BRISTOL MYERS SQUIBB CO COM 110122108 132 1,973 SH   DFND   0 0 1,973
BRUKER CORP COM 116794108 22 290 SH   DFND   0 0 290
BUNGE LIMITED COM G16962105 8 106 SH   DFND   0 0 106
C H ROBINSON WORLDWIDE INC COM NEW 12541W209 3,859 41,200 SH   DFND   0 0 41,200
CANADIAN PAC RY LTD COM 13645T100 23 303 SH   DFND   0 0 303
CAREDX INC COM 14167L103 22 245 SH   DFND   0 0 245
CARLYLE GROUP INC COM COM 14316J108 20 431 SH   DFND   0 0 431
CATALENT INC COM 148806102 51 470 SH   DFND   0 0 470
CEMEX SAB DE CV SPON ADR NEW 151290889 8,108 965,295 SH   DFND   0 0 965,295
CHARGEPOINT HOLDINGS INC COM CL A 15961R105 50 1,451 SH   DFND   0 0 1,451
CHARLES RIV LABS INTL INC COM 159864107 54 146 SH   DFND   0 0 146
CHARTER COMMUNICATIONS INC N CL A 16119P108 32 44 SH   DFND   0 0 44
CHEVRON CORP NEW COM 166764100 14,454 138,000 SH   DFND   0 0 138,000
CHIPOTLE MEXICAN GRILL INC COM 169656105 6 4 SH   DFND   0 0 4
CIGNA CORP NEW COM 125523100 14 58 SH   DFND   0 0 58
CITIGROUP INC COM NEW 172967424 5,464 77,228 SH   DFND   0 0 77,228
CLEAR SECURE INC COM CL A 18467V109 5,200 130,000 SH   DFND   0 0 130,000
COCA COLA CO COM 191216100 4,635 85,660 SH   DFND   0 0 85,660
COGNIZANT TECHNOLOGY SOLUTIO CL A 192446102 31 448 SH   DFND   0 0 448
COINBASE GLOBAL INC COM CL A 19260Q107 76 300 SH   DFND   300 0 0
COLFAX CORP COM 194014106 45 992 SH   DFND   0 0 992
COLGATE PALMOLIVE CO COM 194162103 19 236 SH   DFND   0 0 236
COMCAST CORP NEW CL A 20030N101 77 1,358 SH   DFND   0 0 1,358
COMPANHIA ENERGETICA DE MINA SP ADR N-V PFD 204409601 1,826 767,341 SH   DFND   767,341 0 0
CONSTELLATION BRANDS INC CL A 21036P108 33 142 SH   DFND   0 0 142
COPA HOLDINGS SA CL A P31076105 1,636 21,715 SH   DFND   0 0 21,715
CORTEVA INC COM 22052L104 76 1,721 SH   DFND   0 0 1,721
COSTCO WHSL CORP NEW COM 22160K105 45 113 SH   DFND   0 0 113
CREDICORP LTD COM G2519Y108 763 6,304 SH   DFND   0 0 6,304
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 102 627 SH   DFND   0 0 627
DANAHER CORP DEL COM 235851102 63 236 SH   DFND   0 0 236
DENALI THERAPEUTICS INC COM 24823R105 29 369 SH   DFND   0 0 369
DESKTOP METAL INC COM CL A 25058X105 35 3,050 SH   DFND   0 0 3,050
DEXCOM INC COM 252131107 43 101 SH   DFND   0 0 101
DICKS SPORTING GOODS INC COM 253393102 15 150 SH   DFND   0 0 150
DIDI GLOBAL INC SPONSORED ADS 23292E108 4,119 291,277 SH   DFND   0 0 291,277
DISCOVER FINL SVCS COM 254709108 2,484 21,000 SH   DFND   0 0 21,000
DISNEY WALT CO COM DISNEY 254687106 11,352 64,583 SH   DFND   3,001 0 61,582
DLOCAL LTD CLASS A COM COM G29018101 11,617 221,142 SH   DFND   0 0 221,142
DOLLAR GEN CORP NEW COM 256677105 36 166 SH   DFND   0 0 166
DROPBOX INC CL A 26210C104 43 1,413 SH   DFND   0 0 1,413
DUPONT DE NEMOURS INC COM 26614N102 53 691 SH   DFND   0 0 691
EBANG INTL HLDGS INC CL A SHS G3R33A106 35 11,507 SH   DFND   0 0 11,507
EBAY INC COM 278642103 21 297 SH   DFND   0 0 297
EDWARDS LIFESCIENCES CORP COM 28176E108 43 418 SH   DFND   0 0 418
ELECTRAMECCANICA VEHS CORP COM NEW 284849205 37 8,759 SH   DFND   0 0 8,759
ELECTRONIC ARTS INC COM 285512109 5 37 SH   DFND   0 0 37
EMBRAER S A SP ADR REP 4 COM 29082A107 8,057 532,149 SH   DFND   0 0 532,149
ENERGY RECOVERY INC COM 29270J100 46 2,039 SH   DFND   0 0 2,039
ENERGY TRANSFER EQUITY L P COM UT LTD PTN 29273V100 35 3,291 SH   DFND   0 0 3,291
EOS ENERGY ENTERPRISES INC COM CL A 29415C101 39 2,186 SH   DFND   0 0 2,186
EXACT SCIENCES CORP COM 30063P105 61 487 SH   DFND   0 0 487
EXELIXIS INC COM 30161Q104 44 2,440 SH   DFND   0 0 2,440
F5 NETWORKS INC COM 315616102 41 219 SH   DFND   0 0 219
FACEBOOK INC CALL 30303M902 19 500 SH Call DFND   0 0 500
FACEBOOK INC CL A 30303M102 25,782 74,147 SH   DFND   0 0 74,147
FATE THERAPEUTICS INC COM 31189P102 24 271 SH   DFND   0 0 271
FIDELITY NATIONAL FINANCIAL FNF GROUP COM 31620R303 9 197 SH   DFND   0 0 197
FIDELITY NATL INFORMATION SV COM 31620M106 15 105 SH   DFND   0 0 105
FISERV INC COM 337738108 24 225 SH   DFND   0 0 225
FOCUS FINL PARTNERS INC COM CL A 34417P100 2,891 59,600 SH   DFND   0 0 59,600
FREEPORT-MCMORAN INC CL B 35671D857 29,231 787,690 SH   DFND   0 0 787,690
GENERAL ELECTRIC CO COM 369604103 361 3,357 SH   DFND   0 0 3,357
GENERAL MLS INC COM 370334104 23 371 SH   DFND   0 0 371
GENERAL MTRS CO COM 37045V100 49 832 SH   DFND   0 0 832
GERDAU SA SPON ADR REP PFD 373737105 7,165 1,214,379 SH   DFND   0 0 1,214,379
GILEAD SCIENCES INC COM 375558103 1,328 19,286 SH   DFND   18,419 0 867
GLOBANT S A COM L44385109 27,333 124,704 SH   DFND   0 0 124,704
GRUPO AEROPORTUARIO DEL CENT SPON ADR 400501102 589 11,284 SH   DFND   0 0 11,284
GRUPO AEROPORTUARIO DEL SURE SPON ADR SER B 40051E202 1,063 5,750 SH   DFND   0 0 5,750
GRUPO TELEVISA SA SPON ADR REP ORD 40049J206 22,274 1,559,827 SH   DFND   0 0 1,559,827
GUARDANT HEALTH INC COM 40131M109 50 404 SH   DFND   0 0 404
HCA HEALTHCARE INC COM 40412C101 26 125 SH   DFND   0 0 125
HDFC BANK LTD ADR REPS 3 SHS 40415F101 3,824 52,300 SH   DFND   0 0 52,300
HILTON WORLDWIDE HLDGS INC COM 43300A203 23 192 SH   DFND   0 0 192
HOLOGIC INC COM 436440101 74 1,107 SH   DFND   0 0 1,107
HP INC COM 40434L105 43 1,420 SH   DFND   0 0 1,420
HUMANA INC COM 444859102 11 24 SH   DFND   0 0 24
ILLUMINA INC COM 452327109 158 334 SH   DFND   0 0 334
IMMUNITYBIO INC COM 45256X103 38 2,671 SH   DFND   0 0 2,671
INCYTE CORP COM 45337C102 58 686 SH   DFND   0 0 686
INFOSYS LTD SPONSORED ADR 456788108 613 28,914 SH   DFND   0 0 28,914
INOVIO PHARMACEUTICALS INC COM NEW 45773H201 38 4,096 SH   DFND   0 0 4,096
INSULET CORP COM 45784P101 41 151 SH   DFND   0 0 151
INTEGRA LIFESCIENCES HLDGS C COM NEW 457985208 14 198 SH   DFND   0 0 198
INTELLIA THERAPEUTICS INC COM 45826J105 47 288 SH   DFND   0 0 288
INTERNATIONAL FLAVORS&FRAGRA COM 459506101 7 48 SH   DFND   0 0 48
INTUITIVE SURGICAL INC COM NEW 46120E602 42 46 SH   DFND   0 0 46
INVITAE CORP COM 46185L103 24 712 SH   DFND   0 0 712
IONIS PHARMACEUTICALS INC COM 462222100 35 868 SH   DFND   0 0 868
IQVIA HLDGS INC COM 46266C105 80 331 SH   DFND   0 0 331
IROBOT CORP COM 462726100 40 424 SH   DFND   0 0 424
ISHARES INC CALL 464286900 634 3,700 SH Call DFND   0 0 3,700
ISHARES INC MSCI JPN ETF NEW 46434G822 56,537 837,082 SH   DFND   0 0 837,082
ISHARES INC PUT 464286950 1,066 3,500 SH Put DFND   0 0 3,500
ISHARES INC MSCI PAC JP ETF 464286665 352 6,800 SH   DFND   0 0 6,800
ISHARES INC MSCI CDA ETF 464286509 3,663 98,270 SH   DFND   0 0 98,270
ISHARES INC MSCI STH KOR ETF 464286772 2,283 24,500 SH   DFND   0 0 24,500
ISHARES INC CORE MSCI EMKT 46434G103 723 10,800 SH   DFND   0 0 10,800
ISHARES INC MSCI EM ASIA ETF 464286426 2,868 31,000 SH   DFND   0 0 31,000
ISHARES INC MSCI GERMANY ETF 464286806 3,783 109,332 SH   DFND   0 0 109,332
ISHARES INC MSCI EURZONE ETF 464286608 181 3,673 SH   DFND   0 0 3,673
ISHARES INC MSCI FRANCE ETF 464286707 3,456 91,300 SH   DFND   0 0 91,300
ISHARES TR CALL 464287904 23 2,250 SH Call DFND   0 0 2,250
ISHARES TR CHINA LG-CAP ETF 464287184 7,624 164,551 SH   DFND   0 0 164,551
ISHARES TR MSCI EAFE ETF 464287465 694 8,800 SH   DFND   0 0 8,800
ISHARES TR PUT 464287956 1 2,500 SH Put DFND   0 0 2,500
ISHARES TR RUSSELL 2000 ETF 464287655 2,386 10,401 SH   DFND   0 0 10,401
ISHARES TR MSCI ACWI ETF 464288257 4,402 43,500 SH   DFND   0 0 43,500
ISHARES TR MSCI EURO FL ETF 464289180 45 2,300 SH   DFND   0 0 2,300
ISHARES TR MSCI CHINA ETF 46429B671 3,957 48,000 SH   DFND   0 0 48,000
ISHARES TR JPMORGAN USD EMG 464288281 1,687 15,000 SH   DFND   0 0 15,000
ISHARES TR IBOXX INV CP ETF 464287242 9,311 69,298 SH   DFND   0 0 69,298
ISHARES TR S&P 500 VAL ETF 464287408 4,355 29,500 SH   DFND   0 0 29,500
ISHARES TR SHORT TREAS BD 464288679 12,290 111,236 SH   DFND   0 0 111,236
ISHARES TR 10-20 YR TRS ETF 464288653 5,564 37,865 SH   DFND   0 0 37,865
ISHARES TR US TREAS BD ETF 46429B267 4,306 161,890 SH   DFND   0 0 161,890
ISHARES TR NA TEC SFTWR ETF 464287515 2,028 5,200 SH   DFND   0 0 5,200
ISHARES TR RUS 1000 VAL ETF 464287598 973 6,135 SH   DFND   0 0 6,135
ISHARES TR GL CLEAN ENE ETF 464288224 1,971 84,000 SH   DFND   0 0 84,000
ISHARES TR US AER DEF ETF 464288760 1,906 17,400 SH   DFND   0 0 17,400
JANUS HENDERSON GROUP PLC ORD SHS G4474Y214 14 372 SH   DFND   0 0 372
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 43 241 SH   DFND   0 0 241
JEFFERIES FINL GROUP INC COM 47233W109 24 707 SH   DFND   0 0 707
JOHNSON & JOHNSON COM 478160104 494 2,997 SH   DFND   2,762 0 235
JPMORGAN CHASE & CO COM 46625H100 18,984 122,053 SH   DFND   0 0 122,053
JUNIPER NETWORKS INC COM 48203R104 39 1,442 SH   DFND   0 0 1,442
KKR & CO INC CL A 48251W104 16 266 SH   DFND   0 0 266
KRANESHARES TR CALL 500767906 0 1,050 SH Call DFND   0 0 1,050
KROGER CO COM 501044101 68 1,770 SH   DFND   0 0 1,770
LABORATORY CORP AMER HLDGS COM NEW 50540R409 108 390 SH   DFND   0 0 390
LEGALZOOM COM INC COM 52466B103 167 4,408 SH   DFND   0 0 4,408
LENDINGCLUB CORP COM NEW 52603A208 46 2,514 SH   DFND   0 0 2,514
LILLY ELI & CO COM 532457108 49 212 SH   DFND   0 0 212
LIVANOVA PLC SHS G5509L101 45 530 SH   DFND   0 0 530
LOCKHEED MARTIN CORP COM 539830109 33 87 SH   DFND   0 0 87
LOUISIANA PAC CORP COM 546347105 8 133 SH   DFND   0 0 133
LOWES COS INC COM 548661107 97 499 SH   DFND   0 0 499
LULULEMON ATHLETICA INC COM 550021109 18 49 SH   DFND   0 0 49
LUMINAR TECHNOLOGIES INC COM CL A 550424105 37 1,682 SH   DFND   0 0 1,682
MARAVAI LIFESCIENCES HLDGS I COM CL A 56600D107 18 424 SH   DFND   0 0 424
MARQETA INC CLASS A COM 57142B104 201 7,147 SH   DFND   0 0 7,147
MASTEC INC COM 576323109 2,122 20,000 SH   DFND   0 0 20,000
MASTERCARD INCORPORATED CL A 57636Q104 15 42 SH   DFND   0 0 42
MATCH GROUP INC NEW COM 57667L107 18 112 SH   DFND   0 0 112
MEDPACE HLDGS INC COM 58506Q109 24 135 SH   DFND   0 0 135
MEDTRONIC PLC SHS G5960L103 39 311 SH   DFND   0 0 311
MERCADOLIBRE INC COM 58733R102 25,255 16,212 SH   DFND   0 0 16,212
MERCK & CO INC COM 58933Y105 37 479 SH   DFND   0 0 479
MERCURY SYS INC COM 589378108 41 621 SH   DFND   0 0 621
METLIFE INC COM 59156R108 14 242 SH   DFND   0 0 242
MGM RESORTS INTERNATIONAL COM 552953101 21 486 SH   DFND   0 0 486
MICRON TECHNOLOGY INC COM 595112103 12 145 SH   DFND   0 0 145
MICROSOFT CORP COM 594918104 22,846 84,332 SH   DFND   6,666 0 77,666
MICROVISION INC DEL COM NEW 594960304 32 1,933 SH   DFND   0 0 1,933
MIRATI THERAPEUTICS INC COM 60468T105 27 168 SH   DFND   0 0 168
MODERNA INC COM 60770K107 136 580 SH   DFND   0 0 580
MONDAY COM LTD SHS M7S64H106 54 242 SH   DFND   0 0 242
MONDELEZ INTL INC CL A 609207105 24 389 SH   DFND   0 0 389
MONGODB INC CL A 60937P106 45 124 SH   DFND   0 0 124
MOODYS CORP COM 615369105 20 55 SH   DFND   0 0 55
MORGAN STANLEY COM NEW 617446448 10 110 SH   DFND   0 0 110
NANO DIMENSION LTD SPONSORD ADS NEW 63008G203 43 5,200 SH   DFND   0 0 5,200
NATERA INC COM 632307104 38 333 SH   DFND   0 0 333
NEKTAR THERAPEUTICS COM 640268108 33 1,936 SH   DFND   0 0 1,936
NEOGENOMICS INC COM NEW 64049M209 19 411 SH   DFND   0 0 411
NETFLIX INC COM 64110L106 16,274 30,809 SH   DFND   2,292 0 28,517
NETSCOUT SYS INC COM 64115T104 39 1,363 SH   DFND   0 0 1,363
NEUROCRINE BIOSCIENCES INC COM 64125C109 19 197 SH   DFND   0 0 197
NEXTERA ENERGY INC COM 65339F101 1,165 15,897 SH   DFND   15,897 0 0
NIKE INC CL B 654106103 59 381 SH   DFND   228 0 153
NIKOLA CORP COM 654110105 42 2,349 SH   DFND   0 0 2,349
NORTHROP GRUMMAN CORP COM 666807102 19 53 SH   DFND   0 0 53
NOVAVAX INC COM NEW 670002401 37 172 SH   DFND   0 0 172
NRG ENERGY INC COM NEW 629377508 24 607 SH   DFND   0 0 607
NVIDIA CORP COM 67066G104 4,145 19,569 SH   DFND   385 0 19,184
NXP SEMICONDUCTORS N V COM N6596X109 7 36 SH   DFND   0 0 36
ONECONNECT FINL TECHNOLOGY C SPONSORD ADS 68248T105 39 3,237 SH   DFND   0 0 3,237
ORCHARD THERAPEUTICS PLC ADS 68570P101 34 7,825 SH   DFND   0 0 7,825
OSHKOSH CORP COM 688239201 3,178 25,500 SH   DFND   0 0 25,500
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 30 868 SH   DFND   0 0 868
PAYPAL HLDGS INC COM 70450Y103 368 1,263 SH   DFND   880 0 383
PEPSICO INC COM 713448108 44 299 SH   DFND   0 0 299
PERKINELMER INC COM 714046109 77 501 SH   DFND   0 0 501
PETROLEO BRASILEIRO SA PETRO CALL 71654V908 18 1,483 SH Call DFND   0 0 1,483
PETROLEO BRASILEIRO SA PETRO SP ADR NON VTG 71654V101 137,182 11,615,772 SH   DFND   11,615,772 0 0
PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408 117,234 9,585,806 SH   DFND   9,585,806 0 0
PFIZER INC COM 717081103 88 2,237 SH   DFND   0 0 2,237
PG&E CORP COM 69331C108 10 945 SH   DFND   0 0 945
PHILLIPS 66 COM 718546104 1,742 20,300 SH   DFND   0 0 20,300
PILGRIMS PRIDE CORP COM 72147K108 12,544 565,568 SH   DFND   0 0 565,568
PINNACLE FINL PARTNERS INC COM 72346Q104 2,129 24,110 SH   DFND   0 0 24,110
PLAINS ALL AMERN PIPELINE L UNIT LTD PARTN 726503105 8 689 SH   DFND   0 0 689
PPD INC COM 69355F102 23 500 SH   DFND   0 0 500
PRA HEALTH SCIENCES INC COM 69354M108 49 296 SH   DFND   0 0 296
PROCTER AND GAMBLE CO COM 742718109 60 441 SH   DFND   0 0 441
PROQR THRAPEUTICS N V SHS EURO N71542109 43 6,359 SH   DFND   0 0 6,359
PRUDENTIAL FINL INC COM 744320102 40 394 SH   DFND   0 0 394
QUALCOMM INC COM 747525103 34 239 SH   DFND   0 0 239
QUEST DIAGNOSTICS INC COM 74834L100 78 589 SH   DFND   0 0 589
QUIDEL CORP COM 74838J101 23 179 SH   DFND   0 0 179
RADWARE LTD ORD M81873107 43 1,384 SH   DFND   0 0 1,384
REGENERON PHARMACEUTICALS COM 75886F107 142 254 SH   DFND   0 0 254
REPLIGEN CORP COM 759916109 37 187 SH   DFND   0 0 187
RIDGEBIO PHARMA INC COM COM 10806X102 11 180 SH   DFND   0 0 180
ROKU INC COM CL A 77543R102 18 39 SH   DFND   0 0 39
ROMEO POWER INC COM 776153108 34 4,158 SH   DFND   0 0 4,158
ROSS STORES INC COM 778296103 19 156 SH   DFND   0 0 156
SALESFORCE COM INC COM 79466L302 62 254 SH   DFND   0 0 254
SAREPTA THERAPEUTICS INC COM 803607100 14 186 SH   DFND   0 0 186
SCHWAB CHARLES CORP NEW COM 808513105 233 3,200 SH   DFND   0 0 3,200
SEA LTD ADR 81141R100 3,269 11,904 SH   DFND   0 0 11,904
SEAGEN INC COM 81181C104 28 180 SH   DFND   0 0 180
SELECT SECTOR SPDR TR CALL 81369Y906 76 1,800 SH Call DFND   0 0 1,800
SELECT SECTOR SPDR TR CALL 81369Y905 115 2,850 SH Call DFND   0 0 2,850
SELECT SECTOR SPDR TR ENERGY 81369Y506 3,313 61,500 SH   DFND   0 0 61,500
SELECT SECTOR SPDR TR SBI INT-FINL 81369Y605 8,745 238,354 SH   DFND   0 0 238,354
SELECT SECTOR SPDR TR TECHNOLOGY 81369Y803 10,311 69,828 SH   DFND   0 0 69,828
SELECT SECTOR SPDR TR SBI INT-UTILS 81369Y886 6,911 109,300 SH   DFND   0 0 109,300
SELECT SECTOR SPDR TR SBI INT-INDS 81369Y704 6,813 66,530 SH   DFND   0 0 66,530
SELECT SECTOR SPDR TR SBI CONS DISCR 81369Y407 11,561 64,750 SH   DFND   0 0 64,750
SELECT SECTOR SPDR TR SBI MATERIALS 81369Y100 1,844 22,400 SH   DFND   0 0 22,400
SELECT SECTOR SPDR TR RL EST SEL SEC 81369Y860 5,315 119,900 SH   DFND   0 0 119,900
SENTINELONE INC CL A 81730H109 5,313 125,000 SH   DFND   0 0 125,000
SERVICENOW INC COM 81762P102 47 86 SH   DFND   0 0 86
SHERWIN WILLIAMS CO COM 824348106 20 72 SH   DFND   0 0 72
SILICON LABORATORIES INC COM 826919102 47 306 SH   DFND   0 0 306
SLACK TECHNOLOGIES INC COM CL A 83088V102 41 933 SH   DFND   0 0 933
SLM CORP COM 78442P106 15 719 SH   DFND   0 0 719
SMUCKER J M CO COM NEW 832696405 33 254 SH   DFND   0 0 254
SOHU COM LTD SPONSORED ADS 83410S108 44 2,386 SH   DFND   0 0 2,386
SONY CORP SPONSORED ADR 835699307 491 5,046 SH   DFND   0 0 5,046
SOUTHERN COPPER CORP COM 84265V105 257 4,000 SH   DFND   0 0 4,000
SPDR GOLD TR GOLD SHS 78463V107 13,802 83,332 SH   DFND   0 0 83,332
SPDR INDEX SHS FDS ASIA PACIF ETF 78463X301 2,758 20,500 SH   DFND   0 0 20,500
SPDR S&P 500 ETF TR CALL 78462F903 3,089 750 SH Call DFND   0 0 750
SPDR S&P 500 ETF TR PUT 78462F953 2,254 5,880 SH Put DFND   0 0 5,880
SPDR S&P 500 ETF TR TR UNIT 78462F103 221,991 518,599 SH   DFND   0 0 518,599
SPDR SER TR S&P OILGAS EXP 78468R556 3,578 37,000 SH   DFND   0 0 37,000
SPDR SERIES TRUST S&P METALS MNG 78464A755 495 11,500 SH   DFND   0 0 11,500
SPDR SERIES TRUST S&P RETAIL ETF 78464A714 2,013 20,700 SH   DFND   0 0 20,700
SQUARE INC CL A 852234103 34 140 SH   DFND   0 0 140
STANLEY BLACK & DECKER INC COM 854502101 20 99 SH   DFND   0 0 99
STARBUCKS CORP COM 855244109 13,011 116,369 SH   DFND   0 0 116,369
STONECO LTD COM CL A G85158106 17,710 264,095 SH   DFND   0 0 264,095
SUNNOVA ENERGY INTL INC. COM 86745K104 1,939 51,480 SH   DFND   0 0 51,480
SUNRUN INC COM 86771W105 1,936 34,700 SH   DFND   0 0 34,700
SUPER LEAGUE GAMING INC COM 86804F202 40 7,402 SH   DFND   0 0 7,402
SYNCHRONY FINL COM 87165B103 2,620 54,000 SH   DFND   0 0 54,000
SYNEOS HEALTH INC CL A 87166B102 47 526 SH   DFND   0 0 526
SYNNEX CORP COM 87162W100 14 119 SH   DFND   0 0 119
SYNOPSYS INC COM 871607107 33 121 SH   DFND   0 0 121
T MOBILE US INC COM 872590104 52 357 SH   DFND   0 0 357
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADR 874039100 529 4,401 SH   DFND   0 0 4,401
TARGET CORP COM 87612E106 20 84 SH   DFND   0 0 84
TELADOC HEALTH INC COM 87918A105 106 640 SH   DFND   0 0 640
TENET HEALTHCARE CORP COM NEW 88033G407 60 901 SH   DFND   0 0 901
TERNIUM SA SPON ADR 880890108 23 608 SH   DFND   0 0 608
TESLA INC COM 88160R101 15,461 22,747 SH   DFND   0 0 22,747
TG THERAPEUTICS INC COM 88322Q108 15 397 SH   DFND   0 0 397
THERMO FISHER SCIENTIFIC INC COM 883556102 142 281 SH   DFND   0 0 281
TWILIO INC CL A 90138F102 28 70 SH   DFND   0 0 70
TWIST BIOSCIENCE CORP COM 90184D100 28 207 SH   DFND   0 0 207
TWITTER INC COM 90184L102 16,051 233,272 SH   DFND   0 0 233,272
TYSON FOODS INC CL A 902494103 19 263 SH   DFND   0 0 263
UBER TECHNOLOGIES INC COM 90353T100 13 264 SH   DFND   0 0 264
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 29 301 SH   DFND   0 0 301
UNITED THERAPEUTICS CORP DEL COM 91307C102 44 247 SH   DFND   0 0 247
UNITEDHEALTH GROUP INC COM 91324P102 85 212 SH   DFND   0 0 212
VALERO ENERGY CORP NEW COM 91913Y100 1,850 23,700 SH   DFND   0 0 23,700
VANECK VECTORS ETF TR RUSSIA ETF 92189F403 580 20,000 SH   DFND   0 0 20,000
VANGUARD INDEX FDS S&P 500 ETF SHS 922908363 574,760 1,460,562 SH   DFND   0 0 1,460,562
VANGUARD INDEX FDS REAL ESTATE ETF 922908553 3,410 33,500 SH   DFND   0 0 33,500
VANGUARD INTL EQUITY INDEX F FTSE EUROPE ETF 922042874 116,668 1,734,586 SH   DFND   0 0 1,734,586
VANGUARD INTL EQUITY INDEX F TT WRLD ST ETF 922042742 15,364 148,288 SH   DFND   0 0 148,288
VARONIS SYS INC COM 922280102 48 825 SH   DFND   0 0 825
VELODYNE LIDAR INC COM 92259F101 38 3,578 SH   DFND   0 0 3,578
VERTEX PHARMACEUTICALS INC COM 92532F100 119 592 SH   DFND   0 0 592
VIRGIN GALACTIC HOLDINGS INC COM 92766K106 54 1,168 SH   DFND   0 0 1,168
VISA INC COM CL A 92826C839 3,797 16,238 SH   DFND   0 0 16,238
VISTRA ENERGY CORP COM 92840M102 6 336 SH   DFND   0 0 336
VONTIER CORPORATION COM 928881101 3,831 117,600 SH   DFND   0 0 117,600
VUZIX CORP COM NEW 92921W300 40 2,163 SH   DFND   0 0 2,163
WATERS CORP COM 941848103 50 145 SH   DFND   0 0 145
WELLS FARGO CO NEW COM 949746101 2,382 52,600 SH   DFND   0 0 52,600
WESTERN DIGITAL CORP COM 958102105 13 176 SH   DFND   0 0 176
WHIRLPOOL CORP COM 963320106 9 43 SH   DFND   0 0 43
WISDOMTREE TR INDIA ERNGS FD 97717W422 1,185 35,000 SH   DFND   0 0 35,000
WORKHORSE GROUP INC COM NEW 98138J206 40 2,431 SH   DFND   0 0 2,431
XOMETRY INC CLASS A COM 98423F109 739 8,454 SH   DFND   0 0 8,454
XP INC CL A G98239109 32,304 741,757 SH   DFND   0 0 741,757
XPERI HOLDING CORP COM 98390M103 41 1,823 SH   DFND   0 0 1,823
XUNLEI LTD SPONSORED ADR 98419E108 37 8,008 SH   DFND   0 0 8,008
YELP INC CL A 985817105 40 1,000 SH   DFND   0 0 1,000
ZOETIS INC CL A 98978V103 5,325 28,575 SH   DFND   0 0 28,575
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 1,577 4,074 SH   DFND   4,010 0 64