The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109 64,546 329,620 SH   DFND 1 328,630 0 990
3M CO COM 88579Y101 2,323 11,696 SH   DFND 1 11,696 0 0
ABBOTT LABS COM 002824100 174,641 1,506,437 SH   DFND 1 1,426,750 0 79,687
ABBVIE INC COM 00287Y109 120,630 1,070,936 SH   DFND 1 1,056,455 0 14,481
ABCAM PLC ADS 000380204 3,004 157,759 SH   DFND 1 157,759 0 0
ACACIA RESH CORP ACACIA TCH COM 003881307 1,044 154,413 SH   DFND 1 154,413 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 69,379 1,105,631 SH   DFND 1 1,105,631 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 9,359 149,150 SH   OTR 2 149,150 0 0
ACADIA RLTY TR COM SH BEN INT 004239109 848 38,609 SH   DFND 1 38,609 0 0
ACCENTURE PLC IRELAND SHS CLASS A G1151C101 1,575 5,343 SH   DFND 1 5,343 0 0
ACCOLADE INC COM 00437E102 36,806 677,699 SH   DFND 1 677,699 0 0
ACCOLADE INC COM 00437E102 5,345 98,416 SH   OTR 2 98,416 0 0
ACTIVISION BLIZZARD INC COM 00507V109 5,358 56,139 SH   DFND 1 56,139 0 0
ACV AUCTIONS INC COM CL A 00091G104 9,697 378,347 SH   DFND 1 378,347 0 0
ACV AUCTIONS INC COM CL A 00091G104 2,369 92,423 SH   OTR 2 92,423 0 0
ADECOAGRO S A COM L00849106 18,067 1,799,418 SH   DFND 1 1,799,418 0 0
ADECOAGRO S A COM L00849106 3,148 313,589 SH   OTR 2 313,589 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 3,834,699 6,547,878 SH   DFND 1 6,319,944 0 227,934
ADOBE SYSTEMS INCORPORATED COM 00724F101 53,379 91,146 SH   OTR 2 91,146 0 0
ADVANCED MICRO DEVICES INC COM 007903107 1,819 19,365 SH   DFND 1 19,365 0 0
AES CORP COM 00130H105 86,206 3,306,712 SH   DFND 1 3,306,712 0 0
AES CORP UNIT 99/99/9999 00130H204 33,343 309,964 SH   DFND 1 309,964 0 0
AFFIRM HLDGS INC COM CL A 00827B106 203,506 3,021,613 SH   DFND 1 3,021,613 0 0
AGILENT TECHNOLOGIES INC COM 00846U101 56,031 379,077 SH   DFND 1 376,856 0 2,221
AGILON HEALTH INC COM 00857U107 16,579 408,643 SH   DFND 1 408,643 0 0
AGNICO EAGLE MINES LTD COM 008474108 10,417 172,319 SH   DFND 1 172,185 0 134
AIRBNB INC COM CL A 009066101 1,819,652 11,882,275 SH   DFND 1 11,142,488 0 739,787
AIRBNB INC COM CL A 009066101 61,985 404,762 SH   OTR 2 404,762 0 0
AKOYA BIOSCIENCES INC COM 00974H104 4,580 236,797 SH   DFND 1 236,797 0 0
ALCOA CORP COM 013872106 8,728 236,922 SH   DFND 1 236,739 0 183
ALCON AG ORD SHS H01301128 56,471 806,313 SH   DFND 1 806,313 0 0
ALCON AG ORD SHS H01301128 749 10,700 SH   OTR 2 10,700 0 0
ALEXANDRIA REAL ESTATE EQ IN COM 015271109 30,439 167,301 SH   DFND 1 167,301 0 0
ALIGN TECHNOLOGY INC COM 016255101 140,448 229,865 SH   DFND 1 229,300 0 565
ALLAKOS INC COM 01671P100 9,501 111,292 SH   DFND 1 111,292 0 0
ALLEGHANY CORP MD COM 017175100 26,676 39,990 SH   DFND 1 39,990 0 0
ALLIANT ENERGY CORP COM 018802108 88,535 1,587,782 SH   DFND 1 1,587,782 0 0
ALPHABET INC CAP STK CL A 02079K305 4,165,835 1,706,058 SH   DFND 1 1,638,661 0 67,397
ALPHABET INC CAP STK CL A 02079K305 89,790 36,772 SH   OTR 2 36,772 0 0
ALPHABET INC CAP STK CL C 02079K107 3,406,094 1,359,002 SH   DFND 1 1,286,139 0 72,863
ALPHABET INC CAP STK CL C 02079K107 43,550 17,376 SH   OTR 2 17,376 0 0
ALTICE USA INC CL A 02156K103 3,816 111,761 SH   DFND 1 111,761 0 0
AMAZON COM INC COM 023135106 9,261,829 2,692,267 SH   DFND 1 2,572,253 0 120,014
AMAZON COM INC COM 023135106 192,240 55,881 SH   OTR 2 55,881 0 0
AMEREN CORP COM 023608102 175,420 2,191,655 SH   DFND 1 2,191,655 0 0
AMERESCO INC CL A 02361E108 8,500 135,517 SH   DFND 1 135,412 0 105
AMERICAN CAMPUS CMNTYS INC COM 024835100 82,420 1,764,117 SH   DFND 1 1,764,117 0 0
AMERICAN ELEC PWR CO INC COM 025537101 67,136 793,662 SH   DFND 1 793,662 0 0
AMERICAN ELEC PWR CO INC UNIT 08/01/2021 025537127 7,400 150,622 SH   DFND 1 150,622 0 0
AMERICAN EXPRESS CO COM 025816109 868 5,253 SH   DFND 1 5,253 0 0
AMERICAN TOWER CORP NEW COM 03027X100 68,331 252,945 SH   DFND 1 246,886 0 6,059
AMERICAN WTR WKS CO INC NEW COM 030420103 83,006 538,545 SH   DFND 1 520,051 0 18,494
AMERIS BANCORP COM 03076K108 13,779 272,153 SH   DFND 1 272,153 0 0
AMERIS BANCORP COM 03076K108 1,779 35,143 SH   OTR 2 35,143 0 0
AMETEK INC COM 031100100 52,524 393,437 SH   DFND 1 391,126 0 2,311
AMGEN INC COM 031162100 1,550 6,357 SH   DFND 1 6,357 0 0
AMICUS THERAPEUTICS INC COM 03152W109 52,025 5,396,716 SH   DFND 1 5,396,716 0 0
AMICUS THERAPEUTICS INC COM 03152W109 3,518 364,969 SH   OTR 2 364,969 0 0
AMKOR TECHNOLOGY INC COM 031652100 1,872 79,096 SH   DFND 1 79,096 0 0
AMN HEALTHCARE SVCS INC COM 001744101 1,396 14,398 SH   DFND 1 14,398 0 0
AMPHENOL CORP NEW CL A 032095101 55,116 805,667 SH   DFND 1 800,955 0 4,712
ANTERO MIDSTREAM CORP COM 03676B102 4,254 409,437 SH   DFND 1 409,437 0 0
AON PLC SHS CL A G0403H108 1,555 6,514 SH   DFND 1 6,514 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 149,472 2,365,055 SH   DFND 1 2,365,055 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 5,338 84,469 SH   OTR 2 84,469 0 0
APOLLO GLOBAL MGMT INC COM CL A 03768E105 56,349 905,930 SH   DFND 1 901,815 0 4,115
APPLE INC COM 037833100 6,597,098 48,168,063 SH   DFND 1 45,900,135 0 2,267,928
APPLE INC COM 037833100 146,202 1,067,481 SH   OTR 2 1,067,481 0 0
APTIV PLC SHS G6095L109 45,300 287,929 SH   DFND 1 286,249 0 1,680
ARAMARK COM 03852U106 9,621 258,275 SH   DFND 1 258,275 0 0
ARES MANAGEMENT CORPORATION CL A COM STK 03990B101 77,307 1,215,703 SH   DFND 1 1,210,608 0 5,095
ARGENX SE SPONSORED ADR 04016X101 224,718 746,401 SH   DFND 1 745,913 0 488
ARGENX SE SPONSORED ADR 04016X101 1,492 4,954 SH   OTR 2 4,954 0 0
ARRIVAL GROUP SHS L0423Q108 9,296 593,216 SH   DFND 1 589,454 0 3,762
ARTISAN PARTNERS ASSET MGMT CL A 04316A108 942 18,538 SH   DFND 1 18,538 0 0
ARVINAS INC COM 04335A105 12,600 163,635 SH   DFND 1 163,635 0 0
ASBURY AUTOMOTIVE GROUP INC COM 043436104 1,135 6,625 SH   DFND 1 6,625 0 0
ASGN INC COM 00191U102 40,015 412,826 SH   DFND 1 412,826 0 0
ASGN INC COM 00191U102 5,770 59,524 SH   OTR 2 59,524 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210 26,533 38,407 SH   DFND 1 38,407 0 0
ASPEN TECHNOLOGY INC COM 045327103 1,485 10,798 SH   DFND 1 10,798 0 0
ASSETMARK FINL HLDGS INC COM 04546L106 12,197 486,717 SH   DFND 1 486,717 0 0
ASSETMARK FINL HLDGS INC COM 04546L106 1,757 70,114 SH   OTR 2 70,114 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 182,625 3,048,839 SH   DFND 1 3,048,839 0 0
ATKORE INC COM 047649108 1,714 24,134 SH   DFND 1 24,134 0 0
ATLANTIC UN BANKSHARES CORP COM 04911A107 9,881 272,814 SH   DFND 1 272,814 0 0
ATLANTIC UN BANKSHARES CORP COM 04911A107 2,763 76,281 SH   OTR 2 76,281 0 0
ATLASSIAN CORP PLC CL A G06242104 1,717,777 6,687,597 SH   DFND 1 6,377,858 0 309,739
ATLASSIAN CORP PLC CL A G06242104 53,112 206,776 SH   OTR 2 206,776 0 0
AUTOMATIC DATA PROCESSING IN COM 053015103 1,940 9,769 SH   DFND 1 9,769 0 0
AVALARA INC COM 05338G106 41,632 257,303 SH   DFND 1 255,853 0 1,450
AVALONBAY CMNTYS INC COM 053484101 11,238 53,850 SH   DFND 1 53,850 0 0
AVANGRID INC COM 05351W103 34,204 665,065 SH   DFND 1 665,065 0 0
AVANTOR INC COM 05352A100 141,145 3,974,792 SH   DFND 1 3,966,514 0 8,278
AVERY DENNISON CORP COM 053611109 22,348 106,298 SH   DFND 1 106,298 0 0
AVID BIOSERVICES INC COM 05368M106 16,425 640,366 SH   DFND 1 640,366 0 0
AVID BIOSERVICES INC COM 05368M106 4,378 170,681 SH   OTR 2 170,681 0 0
AVIENT CORPORATION COM 05368V106 72,715 1,479,159 SH   DFND 1 1,479,159 0 0
AVIENT CORPORATION COM 05368V106 10,303 209,574 SH   OTR 2 209,574 0 0
AXCELIS TECHNOLOGIES INC COM NEW 054540208 978 24,196 SH   DFND 1 24,196 0 0
AXIS CAP HLDGS LTD SHS G0692U109 36,330 741,281 SH   DFND 1 741,281 0 0
AXIS CAP HLDGS LTD SHS G0692U109 3,782 77,174 SH   OTR 2 77,174 0 0
AXONICS INC COM 05465P101 18,283 288,324 SH   DFND 1 288,324 0 0
AXOS FINANCIAL INC COM 05465C100 2,294 49,446 SH   DFND 1 49,446 0 0
AZEK CO INC CL A 05478C105 33,722 794,216 SH   DFND 1 789,279 0 4,937
BALLYS CORPORATION COM 05875B106 29,140 538,523 SH   DFND 1 538,523 0 0
BALLYS CORPORATION COM 05875B106 4,351 80,411 SH   OTR 2 80,411 0 0
BANDWIDTH INC COM CL A 05988J103 51,815 375,693 SH   DFND 1 375,693 0 0
BANDWIDTH INC COM CL A 05988J103 10,130 73,447 SH   OTR 2 73,447 0 0
BANKUNITED INC COM 06652K103 50,072 1,172,903 SH   DFND 1 1,172,903 0 0
BANKUNITED INC COM 06652K103 6,412 150,207 SH   OTR 2 150,207 0 0
BARRICK GOLD CORP COM 067901108 13,313 643,759 SH   DFND 1 643,227 0 532
BEAZER HOMES USA INC COM NEW 07556Q881 1,262 65,400 SH   DFND 1 65,400 0 0
BEIGENE LTD SPONSORED ADR 07725L102 9,345 27,230 SH   DFND 1 27,230 0 0
BELDEN INC COM 077454106 933 18,453 SH   DFND 1 18,453 0 0
BEST BUY INC COM 086516101 3,308 28,766 SH   DFND 1 28,766 0 0
BHP GROUP LTD SPONSORED ADS 088606108 18,097 248,480 SH   DFND 1 248,282 0 198
BILIBILI INC SPONS ADS REP Z 090040106 144,412 1,185,266 SH   DFND 1 1,185,266 0 0
BILIBILI INC SPONS ADS REP Z 090040106 1,306 10,715 SH   OTR 2 10,715 0 0
BIO RAD LABS INC CL A 090572207 18,852 29,260 SH   DFND 1 29,260 0 0
BIOLIFE SOLUTIONS INC COM NEW 09062W204 11,053 248,321 SH   DFND 1 248,321 0 0
BIOLIFE SOLUTIONS INC COM NEW 09062W204 2,494 56,037 SH   OTR 2 56,037 0 0
BIONTECH SE SPONSORED ADS 09075V102 57,952 258,855 SH   DFND 1 258,855 0 0
BJS RESTAURANTS INC COM 09180C106 8,773 178,515 SH   DFND 1 178,515 0 0
BJS RESTAURANTS INC COM 09180C106 1,088 22,148 SH   OTR 2 22,148 0 0
BJS WHSL CLUB HLDGS INC COM 05550J101 33,926 713,035 SH   DFND 1 713,035 0 0
BJS WHSL CLUB HLDGS INC COM 05550J101 4,701 98,792 SH   OTR 2 98,792 0 0
BK OF AMERICA CORP COM 060505104 221,881 5,381,553 SH   DFND 1 5,319,256 0 62,297
BLACKSTONE GROUP INC COM 09260D107 126,825 1,305,595 SH   DFND 1 1,305,595 0 0
BLOOMIN BRANDS INC COM 094235108 49,479 1,823,116 SH   DFND 1 1,823,116 0 0
BLOOMIN BRANDS INC COM 094235108 6,909 254,569 SH   OTR 2 254,569 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 35,580 404,501 SH   DFND 1 404,501 0 0
BOISE CASCADE CO DEL COM 09739D100 2,036 34,886 SH   DFND 1 34,886 0 0
BOOT BARN HLDGS INC COM 099406100 35,650 424,147 SH   DFND 1 424,147 0 0
BOOT BARN HLDGS INC COM 099406100 5,998 71,365 SH   OTR 2 71,365 0 0
BOSTON BEER INC CL A 100557107 8,611 8,436 SH   DFND 1 8,436 0 0
BOYD GAMING CORP COM 103304101 1,118 18,189 SH   DFND 1 18,189 0 0
BRIGHTSPHERE INVT GROUP INC COM 10948W103 78,162 3,336,005 SH   DFND 1 3,336,005 0 0
BRIGHTSPHERE INVT GROUP INC COM 10948W103 9,596 409,543 SH   OTR 2 409,543 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 122,677 1,835,930 SH   DFND 1 1,835,930 0 0
BROADCOM INC COM 11135F101 191,821 402,276 SH   DFND 1 398,928 0 3,348
BROADRIDGE FINL SOLUTIONS IN COM 11133T103 1,638 10,142 SH   DFND 1 10,142 0 0
BROOKLINE BANCORP INC DEL COM 11373M107 19,181 1,282,963 SH   DFND 1 1,282,963 0 0
BROOKLINE BANCORP INC DEL COM 11373M107 5,265 352,195 SH   OTR 2 352,195 0 0
BROOKS AUTOMATION INC NEW COM 114340102 32,683 343,025 SH   DFND 1 343,025 0 0
BROOKS AUTOMATION INC NEW COM 114340102 5,083 53,346 SH   OTR 2 53,346 0 0
BRUNSWICK CORP COM 117043109 88,518 888,559 SH   DFND 1 888,559 0 0
BRUNSWICK CORP COM 117043109 9,902 99,394 SH   OTR 2 99,394 0 0
BUCKLE INC COM 118440106 2,005 40,299 SH   DFND 1 40,299 0 0
BUMBLE INC COM CL A 12047B105 85,104 1,477,494 SH   DFND 1 1,477,494 0 0
BUNGE LIMITED COM G16962105 10,169 130,125 SH   DFND 1 130,027 0 98
BURLINGTON STORES INC COM 122017106 82,111 255,010 SH   DFND 1 253,801 0 1,209
BURNING ROCK BIOTECH LTD SPONSORED ADS 12233L107 50,076 1,699,809 SH   DFND 1 1,699,809 0 0
BYLINE BANCORP INC COM 124411109 16,019 707,895 SH   DFND 1 707,895 0 0
BYLINE BANCORP INC COM 124411109 3,979 175,815 SH   OTR 2 175,815 0 0
C4 THERAPEUTICS INC COM STK 12529R107 16,777 443,367 SH   DFND 1 443,367 0 0
C4 THERAPEUTICS INC COM STK 12529R107 1,696 44,808 SH   OTR 2 44,808 0 0
CACTUS INC CL A 127203107 29,710 809,091 SH   DFND 1 808,901 0 190
CACTUS INC CL A 127203107 5,381 146,551 SH   OTR 2 146,551 0 0
CAESARS ENTERTAINMENT INC NE COM 12769G100 1,706 16,444 SH   DFND 1 16,444 0 0
CANADIAN NATL RY CO COM 136375102 3,915 37,110 SH   DFND 1 8,851 0 28,259
CAPITAL ONE FINL CORP COM 14040H105 147,482 953,402 SH   DFND 1 953,402 0 0
CARDLYTICS INC COM 14161W105 33,535 264,194 SH   DFND 1 264,194 0 0
CARDLYTICS INC COM 14161W105 6,112 48,156 SH   OTR 2 48,156 0 0
CARVANA CO CL A 146869102 1,201,978 3,982,432 SH   DFND 1 3,817,122 0 165,310
CARVANA CO CL A 146869102 18,621 61,697 SH   OTR 2 61,697 0 0
CATALENT INC COM 148806102 40,808 377,432 SH   DFND 1 375,808 0 1,624
CATERPILLAR INC COM 149123101 44,229 203,232 SH   DFND 1 203,232 0 0
CBIZ INC COM 124805102 1,094 33,391 SH   DFND 1 33,391 0 0
CBRE GROUP INC CL A 12504L109 45,176 526,961 SH   DFND 1 524,563 0 2,398
CENTERPOINT ENERGY INC COM 15189T107 153,154 6,246,067 SH   DFND 1 6,029,025 0 217,042
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100 6,663 300,000 SH   DFND 1 300,000 0 0
CENTURY CMNTYS INC COM 156504300 35,963 540,481 SH   DFND 1 540,481 0 0
CENTURY CMNTYS INC COM 156504300 4,943 74,283 SH   OTR 2 74,283 0 0
CHANGE HEALTHCARE INC COM 15912K100 14,607 633,963 SH   DFND 1 633,963 0 0
CHANNELADVISOR CORP COM 159179100 1,153 47,055 SH   DFND 1 47,055 0 0
CHART INDS INC COM 16115Q308 19,353 132,264 SH   DFND 1 132,164 0 100
CHEESECAKE FACTORY INC COM 163072101 912 16,841 SH   DFND 1 16,841 0 0
CHENIERE ENERGY INC COM NEW 16411R208 172,593 1,989,770 SH   DFND 1 1,917,282 0 72,488
CHEVRON CORP NEW COM 166764100 118,701 1,133,292 SH   DFND 1 1,117,356 0 15,936
CHEWY INC CL A 16679L109 57,067 715,936 SH   DFND 1 489,618 0 226,318
CHIMERA INVT CORP COM NEW 16934Q208 845 56,142 SH   DFND 1 56,142 0 0
CHIPOTLE MEXICAN GRILL INC COM 169656105 1,091,820 704,246 SH   DFND 1 663,976 0 40,270
CHIPOTLE MEXICAN GRILL INC COM 169656105 18,220 11,752 SH   OTR 2 11,752 0 0
CHUBB LIMITED COM H1467J104 198,484 1,248,800 SH   DFND 1 1,248,800 0 0
CIGNA CORP NEW COM 125523100 143,677 606,052 SH   DFND 1 606,052 0 0
CIMAREX ENERGY CO COM 171798101 12,843 177,273 SH   DFND 1 177,127 0 146
CISCO SYS INC COM 17275R102 96,112 1,813,433 SH   DFND 1 1,778,813 0 34,620
CITI TRENDS INC COM 17306X102 30,833 354,402 SH   DFND 1 354,402 0 0
CITI TRENDS INC COM 17306X102 4,464 51,309 SH   OTR 2 51,309 0 0
CITIGROUP INC COM NEW 172967424 151,843 2,146,190 SH   DFND 1 2,146,190 0 0
CLEAR SECURE INC COM CL A 18467V109 14,599 364,983 SH   DFND 1 364,983 0 0
CLEAR SECURE INC COM CL A 18467V109 1,401 35,017 SH   OTR 2 35,017 0 0
CMS ENERGY CORP COM 125896100 120,734 2,043,576 SH   DFND 1 2,017,910 0 25,666
CNO FINL GROUP INC COM 12621E103 1,731 73,303 SH   DFND 1 73,303 0 0
COGNEX CORP COM 192422103 63,627 757,015 SH   DFND 1 753,741 0 3,274
COHU INC COM 192576106 793 21,565 SH   DFND 1 21,565 0 0
COLFAX CORP COM 194014106 60,863 1,328,591 SH   DFND 1 1,328,591 0 0
COLFAX CORP COM 194014106 8,492 185,378 SH   OTR 2 185,378 0 0
COMCAST CORP NEW CL A 20030N101 59,205 1,038,328 SH   DFND 1 1,000,840 0 37,488
COMMUNITY HEALTH SYS INC NEW COM 203668108 1,488 96,379 SH   DFND 1 96,379 0 0
CONCRETE PUMPING HLDGS INC COM 206704108 9,248 1,091,915 SH   DFND 1 1,091,915 0 0
CONCRETE PUMPING HLDGS INC COM 206704108 2,626 309,987 SH   OTR 2 309,987 0 0
CONOCOPHILLIPS COM 20825C104 342,345 5,621,433 SH   DFND 1 5,621,006 0 427
CONSTELLATION PHARMCETICLS I COM 210373106 2,092 61,895 SH   DFND 1 61,895 0 0
CONSTELLIUM SE CL A SHS F21107101 17,284 912,076 SH   DFND 1 911,349 0 727
COOPER COS INC COM NEW 216648402 125,177 315,888 SH   DFND 1 315,214 0 674
COPART INC COM 217204106 1,585 12,022 SH   DFND 1 12,022 0 0
CORNING INC COM 219350105 33,166 810,894 SH   DFND 1 810,894 0 0
COSTAR GROUP INC COM 22160N109 83,105 1,003,442 SH   DFND 1 847,902 0 155,540
COSTCO WHSL CORP NEW COM 22160K105 1,332,154 3,366,829 SH   DFND 1 3,225,716 0 141,113
COSTCO WHSL CORP NEW COM 22160K105 18,018 45,539 SH   OTR 2 45,539 0 0
COUPA SOFTWARE INC COM 22266L106 67,906 259,076 SH   DFND 1 181,508 0 77,568
COUPANG INC CL A 22266T109 18,841 450,522 SH   DFND 1 450,522 0 0
COUSINS PPTYS INC COM NEW 222795502 43,418 1,180,473 SH   DFND 1 1,180,473 0 0
COUSINS PPTYS INC COM NEW 222795502 5,586 151,882 SH   OTR 2 151,882 0 0
COVETRUS INC COM 22304C100 14,684 543,846 SH   DFND 1 543,846 0 0
COVETRUS INC COM 22304C100 3,666 135,766 SH   OTR 2 135,766 0 0
CRACKER BARREL OLD CTRY STOR COM 22410J106 2,082 14,025 SH   DFND 1 14,025 0 0
CRESTWOOD EQUITY PARTNERS LP UNIT LTD PARTNER 226344208 3,914 130,543 SH   DFND 1 130,543 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 44,554 275,211 SH   DFND 1 275,211 0 0
CROWDSTRIKE HLDGS INC CL A 22788C105 2,182,430 8,684,213 SH   DFND 1 8,276,990 0 407,223
CROWDSTRIKE HLDGS INC CL A 22788C105 55,120 219,331 SH   OTR 2 219,331 0 0
CROWN CASTLE INTL CORP NEW COM 22822V101 3,356 17,199 SH   DFND 1 17,199 0 0
CROWN HLDGS INC COM 228368106 191,080 1,869,486 SH   DFND 1 1,866,943 0 2,543
CURTISS WRIGHT CORP COM 231561101 14,209 119,643 SH   DFND 1 119,643 0 0
CURTISS WRIGHT CORP COM 231561101 1,917 16,142 SH   OTR 2 16,142 0 0
D R HORTON INC COM 23331A109 105,736 1,170,038 SH   DFND 1 1,170,038 0 0
DANAHER CORPORATION COM 235851102 1,470,056 5,477,923 SH   DFND 1 5,191,782 0 286,141
DANAHER CORPORATION COM 235851102 16,938 63,118 SH   OTR 2 63,118 0 0
DARDEN RESTAURANTS INC COM 237194105 22,382 153,314 SH   DFND 1 153,314 0 0
DARLING INGREDIENTS INC COM 237266101 43,225 640,366 SH   DFND 1 640,199 0 167
DCP MIDSTREAM LP COM UT LTD PTN 23311P100 29,025 945,762 SH   DFND 1 945,762 0 0
DEERE & CO COM 244199105 89,143 252,738 SH   DFND 1 252,738 0 0
DELL TECHNOLOGIES INC CL C 24703L202 4,622 46,369 SH   DFND 1 46,369 0 0
DELTA AIR LINES INC DEL COM NEW 247361702 74,884 1,731,030 SH   DFND 1 1,731,030 0 0
DENALI THERAPEUTICS INC COM 24823R105 29,377 374,512 SH   DFND 1 374,512 0 0
DESCARTES SYS GROUP INC COM 249906108 22,128 319,960 SH   DFND 1 319,960 0 0
DESCARTES SYS GROUP INC COM 249906108 3,514 50,810 SH   OTR 2 50,810 0 0
DEVON ENERGY CORP NEW COM 25179M103 66,155 2,266,351 SH   DFND 1 2,265,640 0 711
DEXCOM INC COM 252131107 672,021 1,573,821 SH   DFND 1 1,482,772 0 91,049
DEXCOM INC COM 252131107 10,193 23,871 SH   OTR 2 23,871 0 0
DIAGEO PLC SPON ADR NEW 25243Q205 11,747 61,282 SH   DFND 1 61,282 0 0
DIAMONDBACK ENERGY INC COM 25278X109 26,738 284,778 SH   DFND 1 284,536 0 242
DIAMONDROCK HOSPITALITY CO COM 252784301 1,052 108,427 SH   DFND 1 108,427 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 15,434 413,565 SH   DFND 1 413,565 0 0
DIGITAL TURBINE INC COM NEW 25400W102 1,220 16,047 SH   DFND 1 16,047 0 0
DISNEY WALT CO COM 254687106 179,062 1,018,728 SH   DFND 1 1,003,842 0 14,886
DLOCAL LTD CLASS A COM G29018101 106,709 2,031,392 SH   DFND 1 1,973,619 0 57,773
DLOCAL LTD CLASS A COM G29018101 3,869 73,657 SH   OTR 2 73,657 0 0
DOCUSIGN INC COM 256163106 1,381,622 4,941,954 SH   DFND 1 4,614,825 0 327,129
DOCUSIGN INC COM 256163106 51,477 184,129 SH   OTR 2 184,129 0 0
DOLLAR GEN CORP NEW COM 256677105 6,623 30,607 SH   DFND 1 30,607 0 0
DOLLAR TREE INC COM 256746108 1,519 15,264 SH   DFND 1 15,264 0 0
DOMINION ENERGY INC COM 25746U109 350,563 4,765,026 SH   DFND 1 4,716,587 0 48,439
DOVER CORP COM 260003108 965 6,411 SH   DFND 1 6,411 0 0
DOW INC COM 260557103 93,785 1,482,070 SH   DFND 1 1,482,005 0 65
DTE ENERGY CO COM 233331107 110,998 856,469 SH   DFND 1 856,469 0 0
DUKE ENERGY CORP NEW COM NEW 26441C204 97,635 989,005 SH   DFND 1 989,005 0 0
DYNATRACE INC COM NEW 268150109 478,714 8,194,359 SH   DFND 1 7,197,783 0 996,576
DYNATRACE INC COM NEW 268150109 43,461 743,939 SH   OTR 2 743,939 0 0
E L F BEAUTY INC COM 26856L103 27,593 1,016,662 SH   DFND 1 1,016,662 0 0
E L F BEAUTY INC COM 26856L103 7,225 266,230 SH   OTR 2 266,230 0 0
EAST WEST BANCORP INC COM 27579R104 28,924 403,466 SH   DFND 1 403,466 0 0
EASTERN BANKSHARES INC COM 27627N105 25,249 1,227,420 SH   DFND 1 1,227,420 0 0
EASTERN BANKSHARES INC COM 27627N105 3,113 151,360 SH   OTR 2 151,360 0 0
EBAY INC. COM 278642103 6,550 93,291 SH   DFND 1 93,291 0 0
EDISON INTL COM 281020107 36,404 629,614 SH   DFND 1 602,479 0 27,135
ELLINGTON FINANCIAL INC COM 28852N109 1,018 53,161 SH   DFND 1 53,161 0 0
EMERSON ELEC CO COM 291011104 57,357 595,975 SH   DFND 1 595,975 0 0
ENBRIDGE INC COM 29250N105 57,908 1,446,325 SH   DFND 1 1,384,862 0 61,463
ENDAVA PLC ADS 29260V105 246 2,166 SH   DFND 1 2,166 0 0
ENERGY TRANSFER L P COM UT LTD PTN 29273V100 41,989 3,950,025 SH   DFND 1 3,950,025 0 0
ENERPAC TOOL GROUP CORP CL A COM 292765104 34,992 1,314,520 SH   DFND 1 1,314,520 0 0
ENERPAC TOOL GROUP CORP CL A COM 292765104 5,382 202,173 SH   OTR 2 202,173 0 0
ENPHASE ENERGY INC COM 29355A107 49,830 271,360 SH   DFND 1 270,028 0 1,332
ENSIGN GROUP INC COM 29358P101 1,142 13,174 SH   DFND 1 13,174 0 0
ENTEGRIS INC COM 29362U104 56,517 459,603 SH   DFND 1 457,698 0 1,905
ENTERGY CORP NEW COM 29364G103 69,793 700,032 SH   DFND 1 700,032 0 0
ENTERPRISE FINL SVCS CORP COM 293712105 33,326 718,383 SH   DFND 1 718,383 0 0
ENTERPRISE FINL SVCS CORP COM 293712105 5,262 113,430 SH   OTR 2 113,430 0 0
ENTERPRISE PRODS PARTNERS L COM 293792107 24,303 1,007,170 SH   DFND 1 1,007,170 0 0
EPAM SYS INC COM 29414B104 1,622 3,174 SH   DFND 1 3,174 0 0
EQT CORP COM 26884L109 14,210 638,344 SH   DFND 1 637,846 0 498
EQUINIX INC COM 29444U700 40,896 50,954 SH   DFND 1 48,832 0 2,122
EQUITABLE HLDGS INC COM 29452E101 772 25,361 SH   DFND 1 25,361 0 0
EQUITRANS MIDSTREAM CORP COM 294600101 8,052 946,157 SH   DFND 1 946,157 0 0
ERO COPPER CORP COM 296006109 29,797 1,420,081 SH   DFND 1 1,420,081 0 0
ESSENTIAL UTILS INC COM 29670G102 95,865 2,097,693 SH   DFND 1 2,049,990 0 47,703
ETSY INC COM 29786A106 32,925 159,952 SH   DFND 1 159,008 0 944
EVERBRIDGE INC COM 29978A104 55,164 405,375 SH   DFND 1 405,375 0 0
EVERBRIDGE INC COM 29978A104 7,914 58,160 SH   OTR 2 58,160 0 0
EVERGY INC COM 30034W106 87,991 1,456,078 SH   DFND 1 1,456,078 0 0
EVERSOURCE ENERGY COM 30040W108 48,169 600,313 SH   DFND 1 566,507 0 33,806
EVERTEC INC COM 30040P103 2,004 45,904 SH   DFND 1 45,904 0 0
EVO PMTS INC CL A COM 26927E104 37,687 1,358,589 SH   DFND 1 1,358,589 0 0
EVO PMTS INC CL A COM 26927E104 7,150 257,745 SH   OTR 2 257,745 0 0
EXACT SCIENCES CORP COM 30063P105 33,733 271,365 SH   DFND 1 269,746 0 1,619
EXELON CORP COM 30161N101 51,079 1,152,775 SH   DFND 1 1,119,003 0 33,772
EXXON MOBIL CORP COM 30231G102 4,552 72,170 SH   DFND 1 37,455 0 34,715
FACEBOOK INC CL A 30303M102 4,672,236 13,437,164 SH   DFND 1 12,899,306 0 537,858
FACEBOOK INC CL A 30303M102 62,632 180,127 SH   OTR 2 180,127 0 0
FARO TECHNOLOGIES INC COM 311642102 9,320 119,836 SH   DFND 1 119,836 0 0
FARO TECHNOLOGIES INC COM 311642102 2,639 33,937 SH   OTR 2 33,937 0 0
FATE THERAPEUTICS INC COM 31189P102 64,571 743,992 SH   DFND 1 743,992 0 0
FEDEX CORP COM 31428X106 129,401 433,751 SH   DFND 1 433,751 0 0
FERRARI N V COM N3167Y103 9,005 43,705 SH   DFND 1 43,705 0 0
FIRST ADVANTAGE CORP NEW COM 31846B108 10,976 551,270 SH   DFND 1 551,270 0 0
FIRST ADVANTAGE CORP NEW COM 31846B108 1,827 91,778 SH   OTR 2 91,778 0 0
FIRST BANCORP N C COM 318910106 30,237 739,117 SH   DFND 1 739,117 0 0
FIRST BANCORP N C COM 318910106 5,199 127,075 SH   OTR 2 127,075 0 0
FIRST FNDTN INC COM 32026V104 18,369 816,069 SH   DFND 1 816,069 0 0
FIRST FNDTN INC COM 32026V104 4,078 181,154 SH   OTR 2 181,154 0 0
FIRST SOLAR INC COM 336433107 4,360 48,167 SH   DFND 1 48,130 0 37
FIRSTENERGY CORP COM 337932107 1,048 28,155 SH   DFND 1 28,155 0 0
FIRSTSERVICE CORP NEW COM 33767E202 451 2,628 SH   DFND 1 2,628 0 0
FIVE BELOW INC COM 33829M101 83,492 431,997 SH   DFND 1 430,533 0 1,464
FIVE9 INC COM 338307101 61,105 333,197 SH   DFND 1 331,163 0 2,034
FLUIDIGM CORP DEL COM 34385P108 830 134,757 SH   DFND 1 134,757 0 0
FLYWIRE CORPORATION COM VTG 302492103 10,882 296,199 SH   DFND 1 296,199 0 0
FLYWIRE CORPORATION COM VTG 302492103 1,818 49,482 SH   OTR 2 49,482 0 0
FMC CORP COM NEW 302491303 67,636 625,101 SH   DFND 1 625,075 0 26
FOCUS FINL PARTNERS INC COM CL A 34417P100 57,315 1,181,751 SH   DFND 1 1,181,751 0 0
FOCUS FINL PARTNERS INC COM CL A 34417P100 7,415 152,896 SH   OTR 2 152,896 0 0
FORMFACTOR INC COM 346375108 863 23,670 SH   DFND 1 23,670 0 0
FORTIVE CORP COM 34959J108 74,282 1,065,129 SH   DFND 1 1,065,129 0 0
FREEPORT-MCMORAN INC CL B 35671D857 35,924 968,046 SH   DFND 1 967,479 0 567
FRESHPET INC COM 358039105 80,834 496,034 SH   DFND 1 494,272 0 1,762
FRESHPET INC COM 358039105 6,697 41,095 SH   OTR 2 41,095 0 0
FULLER H B CO COM 359694106 1,067 16,770 SH   DFND 1 16,770 0 0
FULTON FINL CORP PA COM 360271100 1,881 119,195 SH   DFND 1 119,195 0 0
GAMING & LEISURE PPTYS INC COM 36467J108 33,665 726,643 SH   DFND 1 726,643 0 0
GARTNER INC COM 366651107 36,049 148,839 SH   DFND 1 148,198 0 641
GATES INDUSTRIAL CORPRATIN P ORD SHS G39108108 24,426 1,351,749 SH   DFND 1 1,351,749 0 0
GATES INDUSTRIAL CORPRATIN P ORD SHS G39108108 3,360 185,943 SH   OTR 2 185,943 0 0
GENERAC HLDGS INC COM 368736104 3,382 8,146 SH   DFND 1 8,146 0 0
GENERAL ELECTRIC CO COM 369604103 85,230 6,332,067 SH   DFND 1 6,332,067 0 0
GENERAL MTRS CO COM 37045V100 221,420 3,742,098 SH   DFND 1 3,742,098 0 0
GENESIS ENERGY L P UNIT LTD PARTN 371927104 4,714 406,021 SH   DFND 1 406,021 0 0
GENETRON HLDGS LTD ADS 37186H100 42,851 2,127,635 SH   DFND 1 2,127,635 0 0
GFL ENVIRONMENTAL INC SUB VTG SHS 36168Q104 47,459 1,486,796 SH   DFND 1 1,481,989 0 4,807
GFL ENVIRONMENTAL INC UNIT 99/99/9999T 36168Q120 24,462 327,246 SH   DFND 1 281,520 0 45,726
GLOBANT S A COM L44385109 91,796 418,814 SH   DFND 1 417,450 0 1,364
GOLDMAN SACHS GROUP INC COM 38141G104 799,678 2,107,021 SH   DFND 1 1,982,585 0 124,436
GOLDMAN SACHS GROUP INC COM 38141G104 8,257 21,757 SH   OTR 2 21,757 0 0
GOOSEHEAD INS INC COM CL A 38267D109 21,240 166,847 SH   DFND 1 166,847 0 0
GOOSEHEAD INS INC COM CL A 38267D109 5,337 41,927 SH   OTR 2 41,927 0 0
GRAPHITE BIO INC COM 38870X104 9,219 300,000 SH   DFND 1 300,000 0 0
GRAY TELEVISION INC COM 389375106 1,912 81,727 SH   DFND 1 81,727 0 0
GREAT LAKES DREDGE & DOCK CO COM 390607109 67,398 4,613,166 SH   DFND 1 4,613,166 0 0
GREAT LAKES DREDGE & DOCK CO COM 390607109 8,782 601,097 SH   OTR 2 601,097 0 0
GRID DYNAMICS HLDGS INC CL A 39813G109 11,199 745,114 SH   DFND 1 745,114 0 0
GRID DYNAMICS HLDGS INC CL A 39813G109 3,201 213,003 SH   OTR 2 213,003 0 0
GRIFFON CORP COM 398433102 1,394 54,389 SH   DFND 1 54,389 0 0
GUARDANT HEALTH INC COM 40131M109 85,085 685,119 SH   DFND 1 676,498 0 8,621
HALLIBURTON CO COM 406216101 11,011 476,247 SH   DFND 1 475,886 0 361
HAMILTON LANE INC CL A 407497106 15,577 170,947 SH   DFND 1 170,947 0 0
HAMILTON LANE INC CL A 407497106 4,369 47,952 SH   OTR 2 47,952 0 0
HANNON ARMSTRONG SUST INFR C COM 41068X100 6,311 112,396 SH   DFND 1 112,312 0 84
HARSCO CORP COM 415864107 44,214 2,165,249 SH   DFND 1 2,165,249 0 0
HARSCO CORP COM 415864107 6,206 303,905 SH   OTR 2 303,905 0 0
HAWAIIAN HOLDINGS INC COM 419879101 1,679 68,907 SH   DFND 1 68,907 0 0
HCA HEALTHCARE INC COM 40412C101 4,053 19,604 SH   DFND 1 19,604 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 31,158 426,120 SH   DFND 1 426,120 0 0
HEALTHEQUITY INC COM 42226A107 13,528 168,089 SH   DFND 1 168,089 0 0
HEALTHEQUITY INC COM 42226A107 3,445 42,809 SH   OTR 2 42,809 0 0
HEICO CORP NEW COM 422806109 35,343 253,497 SH   DFND 1 252,176 0 1,321
HENRY JACK & ASSOC INC COM 426281101 16,096 98,438 SH   DFND 1 97,985 0 453
HERBALIFE NUTRITION LTD COM SHS G4412G101 2,383 45,199 SH   DFND 1 45,199 0 0
HERC HLDGS INC COM 42704L104 1,473 13,143 SH   DFND 1 13,143 0 0
HERSHEY CO COM 427866108 23,865 137,014 SH   DFND 1 137,014 0 0
HESS CORP COM 42809H107 31,326 358,746 SH   DFND 1 358,449 0 297
HESS MIDSTREAM LP CL A SHS 428103105 4,121 163,209 SH   DFND 1 163,209 0 0
HEXCEL CORP NEW COM 428291108 363 5,811 SH   DFND 1 5,811 0 0
HILL-ROM HLDGS INC COM 431475102 30,358 267,259 SH   DFND 1 267,259 0 0
HILLTOP HOLDINGS INC COM 432748101 1,624 44,620 SH   DFND 1 44,620 0 0
HILTON WORLDWIDE HLDGS INC COM 43300A203 47,400 392,971 SH   DFND 1 390,652 0 2,319
HOLOGIC INC COM 436440101 23,337 349,781 SH   DFND 1 349,781 0 0
HOME BANCSHARES INC COM 436893200 2,426 98,286 SH   DFND 1 98,286 0 0
HOME DEPOT INC COM 437076102 667,984 2,094,715 SH   DFND 1 1,853,667 0 241,048
HOME DEPOT INC COM 437076102 19,904 62,416 SH   OTR 2 62,416 0 0
HONEYWELL INTL INC COM 438516106 8,509 38,793 SH   DFND 1 38,793 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 88,546 945,605 SH   DFND 1 942,176 0 3,429
HOULIHAN LOKEY INC CL A 441593100 28,069 343,186 SH   DFND 1 343,186 0 0
HOULIHAN LOKEY INC CL A 441593100 6,662 81,454 SH   OTR 2 81,454 0 0
HOWARD HUGHES CORP COM 44267D107 17,985 184,533 SH   DFND 1 184,533 0 0
HUBSPOT INC COM 443573100 379,517 651,285 SH   DFND 1 587,459 0 63,826
HUBSPOT INC COM 443573100 26,858 46,091 SH   OTR 2 46,091 0 0
HUMANA INC COM 444859102 374,161 845,141 SH   DFND 1 773,649 0 71,492
HUNT J B TRANS SVCS INC COM 445658107 73,974 453,965 SH   DFND 1 452,332 0 1,633
HURON CONSULTING GROUP INC COM 447462102 12,681 258,002 SH   DFND 1 258,002 0 0
HURON CONSULTING GROUP INC COM 447462102 3,652 74,301 SH   OTR 2 74,301 0 0
I MAB SPONSORED ADS 44975P103 14,293 170,260 SH   DFND 1 170,260 0 0
IAA INC COM 449253103 24,554 450,202 SH   DFND 1 447,548 0 2,654
ILLUMINA INC COM 452327109 38,431 81,214 SH   DFND 1 81,214 0 0
IMMATICS N.V *W EXP 07/01/202 N44445117 1,328 386,035 SH   DFND 1 386,035 0 0
INDEPENDENCE RLTY TR INC COM 45378A106 51,923 2,848,217 SH   DFND 1 2,848,217 0 0
INDEPENDENCE RLTY TR INC COM 45378A106 7,383 405,006 SH   OTR 2 405,006 0 0
INGEVITY CORP COM 45688C107 1,097 13,480 SH   DFND 1 13,480 0 0
INNOVAGE HLDG CORP COM 45784A104 10,122 475,000 SH   DFND 1 475,000 0 0
INSPIRE MED SYS INC COM 457730109 27,908 144,404 SH   DFND 1 144,404 0 0
INSPIRE MED SYS INC COM 457730109 6,866 35,528 SH   OTR 2 35,528 0 0
INSULET CORP COM 45784P101 17,441 63,536 SH   DFND 1 63,078 0 458
INTAPP INC COM 45827U109 11,398 407,082 SH   DFND 1 407,082 0 0
INTAPP INC COM 45827U109 1,902 67,918 SH   OTR 2 67,918 0 0
INTEGRA LIFESCIENCES HLDGS C COM NEW 457985208 18,661 273,462 SH   DFND 1 273,462 0 0
INTEGRA LIFESCIENCES HLDGS C COM NEW 457985208 3,347 49,048 SH   OTR 2 49,048 0 0
INTELLIA THERAPEUTICS INC CALL OPTIONS 45826J105 9,715 60,000 SH Call DFND 1 0 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 166,600 1,028,970 SH   DFND 1 1,028,970 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 6,238 38,527 SH   OTR 2 38,527 0 0
INTERNATIONAL BANCSHARES COR COM 459044103 2,082 48,481 SH   DFND 1 48,481 0 0
INTERSECT ENT INC COM 46071F103 12,551 734,406 SH   DFND 1 734,406 0 0
INTERSECT ENT INC COM 46071F103 2,949 172,579 SH   OTR 2 172,579 0 0
INTUIT COM 461202103 12,355 25,205 SH   DFND 1 25,205 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 794,071 863,458 SH   DFND 1 805,769 0 57,689
INTUITIVE SURGICAL INC COM NEW 46120E602 7,633 8,300 SH   OTR 2 8,300 0 0
INVESTORS BANCORP INC NEW COM 46146L101 995 69,781 SH   DFND 1 69,781 0 0
IQVIA HLDGS INC COM 46266C105 128,425 529,979 SH   DFND 1 528,487 0 1,492
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 1,488 115,623 SH   DFND 1 115,623 0 0
JACK IN THE BOX INC COM 466367109 45,115 404,842 SH   DFND 1 404,842 0 0
JACK IN THE BOX INC COM 466367109 6,269 56,253 SH   OTR 2 56,253 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 61,447 345,906 SH   DFND 1 344,827 0 1,079
JELD-WEN HLDG INC COM 47580P103 49,294 1,877,138 SH   DFND 1 1,877,138 0 0
JELD-WEN HLDG INC COM 47580P103 7,091 270,036 SH   OTR 2 270,036 0 0
JOHNSON CTLS INTL PLC SHS G51502105 243,636 3,549,988 SH   DFND 1 3,549,988 0 0
JPMORGAN CHASE & CO COM 46625H100 359,030 2,308,283 SH   DFND 1 2,227,816 0 80,467
KAMAN CORP COM 483548103 2,616 51,912 SH   DFND 1 51,912 0 0
KANSAS CITY SOUTHERN COM NEW 485170302 3,182 11,229 SH   DFND 1 2,678 0 8,551
KARYOPHARM THERAPEUTICS INC COM 48576U106 1,385 134,230 SH   DFND 1 134,230 0 0
KB HOME COM 48666K109 1,570 38,568 SH   DFND 1 38,568 0 0
KENNAMETAL INC COM 489170100 26,281 731,653 SH   DFND 1 731,653 0 0
KENNAMETAL INC COM 489170100 5,090 141,708 SH   OTR 2 141,708 0 0
KEYSIGHT TECHNOLOGIES INC COM 49338L103 56,154 363,665 SH   DFND 1 349,474 0 14,191
KFORCE INC COM 493732101 1,309 20,798 SH   DFND 1 20,798 0 0
KINDER MORGAN INC DEL COM 49456B101 9,158 502,370 SH   DFND 1 502,370 0 0
KINROSS GOLD CORP COM 496902404 9,916 1,561,648 SH   DFND 1 1,560,282 0 1,366
KKR & CO INC COM 48251W104 20,226 341,426 SH   DFND 1 341,426 0 0
KNIGHT-SWIFT TRANSN HLDGS IN CL A 499049104 678 14,918 SH   DFND 1 14,918 0 0
KONTOOR BRANDS INC COM 50050N103 58,608 1,038,970 SH   DFND 1 1,038,970 0 0
KONTOOR BRANDS INC COM 50050N103 8,939 158,457 SH   OTR 2 158,457 0 0
KRAFT HEINZ CO COM 500754106 1,054 25,855 SH   DFND 1 25,855 0 0
KYMERA THERAPEUTICS INC COM 501575104 9,055 186,701 SH   DFND 1 186,701 0 0
L3HARRIS TECHNOLOGIES INC COM 502431109 42,403 196,176 SH   DFND 1 195,226 0 950
LABORATORY CORP AMER HLDGS COM NEW 50540R409 131,834 477,920 SH   DFND 1 477,920 0 0
LAM RESEARCH CORP COM 512807108 130,101 199,940 SH   DFND 1 199,940 0 0
LANDSTAR SYS INC COM 515098101 1,429 9,044 SH   DFND 1 9,044 0 0
LATTICE SEMICONDUCTOR CORP COM 518415104 16,133 287,179 SH   DFND 1 287,179 0 0
LATTICE SEMICONDUCTOR CORP COM 518415104 3,588 63,860 SH   OTR 2 63,860 0 0
LAUDER ESTEE COS INC CL A 518439104 2,234,341 7,024,462 SH   DFND 1 6,728,073 0 296,389
LAUDER ESTEE COS INC CL A 518439104 29,775 93,609 SH   OTR 2 93,609 0 0
LAUREATE EDUCATION INC CL A 518613203 771 53,169 SH   DFND 1 53,169 0 0
LAZARD LTD SHS A G54050102 54,052 1,194,508 SH   DFND 1 1,194,508 0 0
LAZARD LTD SHS A G54050102 5,113 112,996 SH   OTR 2 112,996 0 0
LENNAR CORP CL A 526057104 42,980 432,612 SH   DFND 1 430,324 0 2,288
LEXINGTON REALTY TRUST COM 529043101 1,333 111,531 SH   DFND 1 111,531 0 0
LIBERTY OILFIELD SVCS INC COM CL A 53115L104 918 64,824 SH   DFND 1 64,824 0 0
LILLY ELI & CO COM 532457108 2,021,442 8,807,256 SH   DFND 1 8,468,624 0 338,632
LILLY ELI & CO COM 532457108 23,810 103,739 SH   OTR 2 103,739 0 0
LINCOLN ELEC HLDGS INC COM 533900106 19,885 150,978 SH   DFND 1 150,978 0 0
LINDE PLC SHS G5494J103 249,347 862,495 SH   DFND 1 862,469 0 26
LITTELFUSE INC COM 537008104 75,004 294,377 SH   DFND 1 293,964 0 413
LITTELFUSE INC COM 537008104 7,150 28,062 SH   OTR 2 28,062 0 0
LIVEVOX HOLDING INC COM CL A 53838L100 8,137 1,024,425 SH   DFND 1 1,024,425 0 0
LOWES COS INC COM 548661107 128,076 660,290 SH   DFND 1 660,290 0 0
LULULEMON ATHLETICA INC COM 550021109 1,690,903 4,632,990 SH   DFND 1 4,410,545 0 222,445
LULULEMON ATHLETICA INC COM 550021109 19,042 52,175 SH   OTR 2 52,175 0 0
LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 1,578 15,342 SH   DFND 1 15,342 0 0
M/I HOMES INC COM 55305B101 963 16,412 SH   DFND 1 16,412 0 0
MACERICH CO COM 554382101 985 53,964 SH   DFND 1 53,964 0 0
MACOM TECH SOLUTIONS HLDGS I COM 55405Y100 49,751 776,389 SH   DFND 1 776,389 0 0
MACOM TECH SOLUTIONS HLDGS I COM 55405Y100 8,432 131,580 SH   OTR 2 131,580 0 0
MACYS INC COM 55616P104 833 43,928 SH   DFND 1 43,928 0 0
MAG SILVER CORP COM 55903Q104 9,357 447,455 SH   DFND 1 447,103 0 352
MAGELLAN MIDSTREAM PRTNRS LP COM UNIT RP LP 559080106 16,586 339,106 SH   DFND 1 339,106 0 0
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109 22,833 759,820 SH   DFND 1 759,820 0 0
MARINEMAX INC COM 567908108 930 19,078 SH   DFND 1 19,078 0 0
MARQETA INC CLASS A COM 57142B104 9,875 351,810 SH   DFND 1 350,293 0 1,517
MARRIOTT INTL INC NEW CL A 571903202 369,562 2,707,017 SH   DFND 1 2,614,262 0 92,755
MARRIOTT INTL INC NEW CL A 571903202 4,570 33,478 SH   OTR 2 33,478 0 0
MARSH & MCLENNAN COS INC COM 571748102 124,844 887,436 SH   DFND 1 887,436 0 0
MARVELL TECHNOLOGY INC COM 573874104 62,207 1,066,467 SH   DFND 1 1,059,962 0 6,505
MASTEC INC COM 576323109 2,271 21,404 SH   DFND 1 21,404 0 0
MASTERCARD INCORPORATED CL A 57636Q104 2,133,993 5,845,116 SH   DFND 1 5,598,665 0 246,451
MASTERCARD INCORPORATED CL A 57636Q104 27,733 75,962 SH   OTR 2 75,962 0 0
MATCH GROUP INC NEW COM 57667L107 3,153,907 19,559,111 SH   DFND 1 18,469,155 0 1,089,956
MATCH GROUP INC NEW COM 57667L107 95,759 593,855 SH   OTR 2 593,855 0 0
MATSON INC COM 57686G105 1,213 18,950 SH   DFND 1 18,950 0 0
MAXIMUS INC COM 577933104 1,101 12,518 SH   DFND 1 12,518 0 0
MAXLINEAR INC COM 57776J100 26,429 622,000 SH   DFND 1 622,000 0 0
MAXLINEAR INC COM 57776J100 6,621 155,829 SH   OTR 2 155,829 0 0
MAYVILLE ENGR CO INC COM 578605107 13,443 668,512 SH   DFND 1 668,512 0 0
MAYVILLE ENGR CO INC COM 578605107 3,755 186,699 SH   OTR 2 186,699 0 0
MCDONALDS CORP COM 580135101 105,966 458,746 SH   DFND 1 452,637 0 6,109
MEDPACE HLDGS INC COM 58506Q109 2,484 14,061 SH   DFND 1 14,061 0 0
MEDTRONIC PLC SHS G5960L103 6,547 52,747 SH   DFND 1 52,747 0 0
MERCADOLIBRE INC COM 58733R102 2,249,663 1,444,137 SH   DFND 1 1,384,276 0 59,861
MERCADOLIBRE INC COM 58733R102 79,274 50,889 SH   OTR 2 50,889 0 0
MERIDIAN BIOSCIENCE INC COM 589584101 1,125 50,708 SH   DFND 1 50,708 0 0
METHODE ELECTRS INC COM 591520200 2,394 48,651 SH   DFND 1 48,651 0 0
METLIFE INC COM 59156R108 191,228 3,195,125 SH   DFND 1 3,195,125 0 0
METTLER TOLEDO INTERNATIONAL COM 592688105 597 431 SH   DFND 1 431 0 0
MGM RESORTS INTERNATIONAL COM 552953101 17,684 414,634 SH   DFND 1 414,634 0 0
MICROCHIP TECHNOLOGY INC. COM 595017104 38,418 256,565 SH   DFND 1 254,880 0 1,685
MICROSOFT CORP COM 594918104 5,272,222 19,461,876 SH   DFND 1 18,698,808 0 763,068
MICROSOFT CORP COM 594918104 63,000 232,557 SH   OTR 2 232,557 0 0
MIRATI THERAPEUTICS INC COM 60468T105 27,943 172,992 SH   DFND 1 172,992 0 0
MODERNA INC COM 60770K107 3,846 16,367 SH   DFND 1 16,367 0 0
MOELIS & CO CL A 60786M105 11,367 199,810 SH   DFND 1 199,810 0 0
MOELIS & CO CL A 60786M105 2,712 47,667 SH   OTR 2 47,667 0 0
MOLINA HEALTHCARE INC COM 60855R100 89,590 354,026 SH   DFND 1 353,005 0 1,021
MONDELEZ INTL INC CL A 609207105 110,978 1,777,349 SH   DFND 1 1,777,349 0 0
MONOLITHIC PWR SYS INC COM 609839105 33,707 90,258 SH   DFND 1 89,666 0 592
MONTE ROSA THERAPEUTICS INC COM 61225M102 6,810 300,000 SH   DFND 1 300,000 0 0
MOODYS CORP COM 615369105 6,322 17,445 SH   DFND 1 17,445 0 0
MORNINGSTAR INC COM 617700109 4,511 17,544 SH   DFND 1 17,544 0 0
MPLX LP COM UNIT REP LTD 55336V100 29,049 981,065 SH   DFND 1 981,065 0 0
MSCI INC COM 55354G100 1,738 3,261 SH   DFND 1 3,261 0 0
MUELLER WTR PRODS INC COM SER A 624758108 7,728 535,882 SH   DFND 1 535,882 0 0
MUELLER WTR PRODS INC COM SER A 624758108 1,825 126,566 SH   OTR 2 126,566 0 0
NATERA INC COM 632307104 70,786 623,502 SH   DFND 1 623,502 0 0
NATIONAL ENERGY SERVICES REU SHS G6375R107 14,463 1,014,976 SH   DFND 1 1,014,218 0 758
NATIONAL STORAGE AFFILIATES COM SHS BEN IN 637870106 34,049 673,456 SH   DFND 1 673,456 0 0
NATIONAL STORAGE AFFILIATES COM SHS BEN IN 637870106 7,334 145,046 SH   OTR 2 145,046 0 0
NATIONAL VISION HLDGS INC COM 63845R107 30,432 595,192 SH   DFND 1 595,192 0 0
NATIONAL VISION HLDGS INC COM 63845R107 7,643 149,478 SH   OTR 2 149,478 0 0
NEOGENOMICS INC COM NEW 64049M209 16,828 372,544 SH   DFND 1 372,544 0 0
NEOGENOMICS INC COM NEW 64049M209 4,097 90,700 SH   OTR 2 90,700 0 0
NETFLIX INC COM 64110L106 3,381,838 6,402,450 SH   DFND 1 6,049,037 0 353,413
NETFLIX INC COM 64110L106 67,590 127,960 SH   OTR 2 127,960 0 0
NEVRO CORP COM 64157F103 61,108 368,586 SH   DFND 1 368,586 0 0
NEVRO CORP COM 64157F103 7,525 45,389 SH   OTR 2 45,389 0 0
NEW FORTRESS ENERGY INC COM CL A 644393100 5,788 152,804 SH   DFND 1 152,741 0 63
NEW JERSEY RES CORP COM 646025106 2,442 61,724 SH   DFND 1 61,724 0 0
NEWELL BRANDS INC COM 651229106 10,618 386,536 SH   DFND 1 386,536 0 0
NEWMONT CORP COM 651639106 21,019 331,635 SH   DFND 1 331,359 0 276
NEXSTAR MEDIA GROUP INC CL A 65336K103 4,676 31,621 SH   DFND 1 31,621 0 0
NEXTERA ENERGY INC COM 65339F101 294,586 4,020,005 SH   DFND 1 3,931,435 0 88,570
NEXTERA ENERGY INC UNIT 99/99/9999 65339F739 5,826 117,943 SH   DFND 1 77,390 0 40,553
NEXTERA ENERGY PARTNERS LP COM UNIT PART IN 65341B106 206,384 2,702,788 SH   DFND 1 2,674,866 0 27,922
NEXTERA ENERGY PARTNERS LP COM UNIT PART IN 65341B106 9,569 125,308 SH   OTR 2 125,308 0 0
NIKE INC CL B 654106103 2,218,254 14,358,564 SH   DFND 1 13,568,574 0 789,990
NIKE INC CL B 654106103 40,023 259,063 SH   OTR 2 259,063 0 0
NISOURCE INC COM 65473P105 34,833 1,421,772 SH   DFND 1 1,361,590 0 60,182
NLIGHT INC COM 65487K100 43,806 1,207,440 SH   DFND 1 1,207,440 0 0
NLIGHT INC COM 65487K100 7,110 195,986 SH   OTR 2 195,986 0 0
NORDSON CORP COM 655663102 55,774 254,085 SH   DFND 1 253,148 0 937
NORFOLK SOUTHN CORP COM 655844108 30,321 114,242 SH   DFND 1 91,710 0 22,532
NORTHWEST NAT HLDG CO COM 66765N105 1,575 29,986 SH   DFND 1 29,986 0 0
NORTONLIFELOCK INC COM 668771108 4,278 157,146 SH   DFND 1 157,146 0 0
NOVA MEASURING INSTRUMENTS L COM M7516K103 252 2,446 SH   DFND 1 2,446 0 0
NOVAVAX INC COM NEW 670002401 25,562 120,398 SH   DFND 1 120,398 0 0
NOVO-NORDISK A S ADR 670100205 40,885 488,059 SH   DFND 1 488,059 0 0
NURIX THERAPEUTICS INC COM 67080M103 22,518 848,769 SH   DFND 1 848,769 0 0
NURIX THERAPEUTICS INC COM 67080M103 1,864 70,268 SH   OTR 2 70,268 0 0
NUSTAR ENERGY LP UNIT COM 67058H102 5,712 316,452 SH   DFND 1 316,452 0 0
NUTRIEN LTD COM 67077M108 9,985 164,743 SH   DFND 1 164,614 0 129
NUVASIVE INC COM 670704105 22,654 334,232 SH   DFND 1 334,232 0 0
NVIDIA CORPORATION COM 67066G104 5,830,104 7,286,720 SH   DFND 1 6,937,848 0 348,872
NVIDIA CORPORATION COM 67066G104 132,496 165,599 SH   OTR 2 165,599 0 0
OCEANEERING INTL INC COM 675232102 1,310 84,135 SH   DFND 1 84,135 0 0
OGE ENERGY CORP COM 670837103 33,062 982,521 SH   DFND 1 982,521 0 0
OKTA INC CL A 679295105 235,774 963,601 SH   DFND 1 932,549 0 31,052
OKTA INC CL A 679295105 5,499 22,475 SH   OTR 2 22,475 0 0
OLD DOMINION FREIGHT LINE IN COM 679580100 1,613 6,356 SH   DFND 1 6,356 0 0
OLINK HLDG AB SPONSORED ADS 680710100 1,929 56,040 SH   DFND 1 56,040 0 0
ON SEMICONDUCTOR CORP COM 682189105 45,690 1,193,578 SH   DFND 1 1,187,576 0 6,002
ONEOK INC NEW COM 682680103 29,680 533,438 SH   DFND 1 503,473 0 29,965
OPEN LENDING CORP COM CL A 68373J104 37,271 864,955 SH   DFND 1 864,955 0 0
OPEN LENDING CORP COM CL A 68373J104 4,929 114,385 SH   OTR 2 114,385 0 0
ORACLE CORP COM 68389X105 8,497 109,154 SH   DFND 1 109,154 0 0
OREILLY AUTOMOTIVE INC COM 67103H107 61,266 108,203 SH   DFND 1 107,689 0 514
ORIC PHARMACEUTICALS INC COM 68622P109 15,967 902,588 SH   DFND 1 902,588 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 1,669 94,357 SH   OTR 2 94,357 0 0
ORTHO CLINICAL DIAGNOSTICS H ORD SHS G6829J107 15,660 731,448 SH   DFND 1 731,448 0 0
OSHKOSH CORP COM 688239201 30,794 247,066 SH   DFND 1 247,066 0 0
OTIS WORLDWIDE CORP COM 68902V107 94,222 1,152,278 SH   DFND 1 1,152,278 0 0
OUTSET MED INC COM 690145107 32,002 640,277 SH   DFND 1 640,277 0 0
OUTSET MED INC COM 690145107 3,674 73,519 SH   OTR 2 73,519 0 0
OVERSTOCK COM INC DEL COM 690370101 1,103 11,961 SH   DFND 1 11,961 0 0
PACWEST BANCORP DEL COM 695263103 34,557 839,585 SH   DFND 1 839,585 0 0
PACWEST BANCORP DEL COM 695263103 5,424 131,776 SH   OTR 2 131,776 0 0
PAGERDUTY INC COM 69553P100 27,827 653,518 SH   DFND 1 653,518 0 0
PAGERDUTY INC COM 69553P100 3,448 80,971 SH   OTR 2 80,971 0 0
PALO ALTO NETWORKS INC COM 697435105 54,171 145,994 SH   DFND 1 145,180 0 814
PARKER-HANNIFIN CORP COM 701094104 4,744 15,448 SH   DFND 1 15,448 0 0
PATRICK INDS INC COM 703343103 1,261 17,269 SH   DFND 1 17,269 0 0
PAYCOM SOFTWARE INC COM 70432V102 38,767 106,658 SH   DFND 1 106,096 0 562
PAYONEER GLOBAL INC COM 70451X104 14,182 1,392,566 SH   DFND 1 1,392,566 0 0
PAYONEER GLOBAL INC COM 70451X104 2,642 254,815 SH   OTR 2 254,815 0 0
PAYPAL HLDGS INC COM 70450Y103 2,901,710 9,955,090 SH   DFND 1 9,545,591 0 409,499
PAYPAL HLDGS INC COM 70450Y103 36,382 124,819 SH   OTR 2 124,819 0 0
PDC ENERGY INC COM 69327R101 120,896 2,640,236 SH   DFND 1 2,639,682 0 554
PDC ENERGY INC COM 69327R101 13,303 290,516 SH   OTR 2 290,516 0 0
PEMBINA PIPELINE CORP COM 706327103 33,672 1,059,798 SH   DFND 1 986,430 0 73,368
PENN NATL GAMING INC COM 707569109 25,983 339,685 SH   DFND 1 339,685 0 0
PEPSICO INC COM 713448108 108,144 729,862 SH   DFND 1 718,550 0 11,312
PERFORMANCE FOOD GROUP CO COM 71377A103 118,942 2,452,906 SH   DFND 1 2,448,166 0 4,740
PERFORMANCE FOOD GROUP CO COM 71377A103 10,171 209,764 SH   OTR 2 209,764 0 0
PERKINELMER INC COM 714046109 5,026 32,548 SH   DFND 1 32,548 0 0
PG&E CORP COM 69331C108 36,327 3,571,978 SH   DFND 1 3,417,708 0 154,270
PHILIP MORRIS INTL INC COM 718172109 7,964 80,356 SH   DFND 1 80,356 0 0
PHILLIPS 66 PARTNERS LP COM UNIT REP INT 718549207 12,460 315,774 SH   DFND 1 315,774 0 0
PHREESIA INC COM 71944F106 75,601 1,233,293 SH   DFND 1 1,233,293 0 0
PHREESIA INC COM 71944F106 8,135 132,709 SH   OTR 2 132,709 0 0
PINNACLE FINL PARTNERS INC COM 72346Q104 58,091 657,954 SH   DFND 1 657,954 0 0
PINNACLE FINL PARTNERS INC COM 72346Q104 7,547 85,478 SH   OTR 2 85,478 0 0
PINTEREST INC CL A 72352L106 68,188 863,690 SH   DFND 1 859,190 0 4,500
PIONEER NAT RES CO COM 723787107 23,636 145,432 SH   DFND 1 145,313 0 119
PLAINS ALL AMERN PIPELINE L UNIT LTD PARTN 726503105 4,698 413,568 SH   DFND 1 413,568 0 0
PLAINS GP HLDGS L P LTD PARTNR INT A 72651A207 19,879 1,664,875 SH   DFND 1 1,664,875 0 0
PLEXUS CORP COM 729132100 1,211 13,253 SH   DFND 1 13,253 0 0
PLUG POWER INC COM NEW 72919P202 1,386 40,533 SH   DFND 1 40,533 0 0
PLYMOUTH INDL REIT INC COM 729640102 8,029 401,025 SH   DFND 1 401,025 0 0
PLYMOUTH INDL REIT INC COM 729640102 1,347 67,305 SH   OTR 2 67,305 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 12,234 358,152 SH   DFND 1 358,152 0 0
PNC FINL SVCS GROUP INC COM 693475105 258,682 1,356,060 SH   DFND 1 1,356,060 0 0
POTLATCHDELTIC CORPORATION COM 737630103 2,265 42,620 SH   DFND 1 42,620 0 0
PRAXIS PRECISION MEDICINES I COM 74006W108 3,610 197,510 SH   DFND 1 197,510 0 0
PRESTIGE CONSMR HEALTHCARE I COM 74112D101 15,174 291,241 SH   DFND 1 291,241 0 0
PRESTIGE CONSMR HEALTHCARE I COM 74112D101 4,302 82,572 SH   OTR 2 82,572 0 0
PRICE T ROWE GROUP INC COM 74144T108 1,710 8,637 SH   DFND 1 8,637 0 0
PRIMERICA INC COM 74164M108 4,487 29,298 SH   DFND 1 29,298 0 0
PRIMORIS SVCS CORP COM 74164F103 1,878 63,822 SH   DFND 1 63,822 0 0
PROCTER AND GAMBLE CO COM 742718109 110,089 815,894 SH   DFND 1 795,701 0 20,193
PROGYNY INC COM 74340E103 56,566 958,738 SH   DFND 1 955,356 0 3,382
PROGYNY INC COM 74340E103 6,032 102,239 SH   OTR 2 102,239 0 0
PROLOGIS INC. COM 74340W103 37,118 310,529 SH   DFND 1 310,529 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109 17,527 2,600,427 SH   DFND 1 2,600,427 0 0
PROSIGHT GLOBAL INC COM 74349J103 4,829 378,443 SH   DFND 1 378,443 0 0
PROVIDENT FINL SVCS INC COM 74386T105 892 38,968 SH   DFND 1 38,968 0 0
PTC INC COM 69370C100 109,264 773,497 SH   DFND 1 772,038 0 1,459
PUBLIC SVC ENTERPRISE GRP IN COM 744573106 124,202 2,079,039 SH   DFND 1 2,017,864 0 61,175
Q2 HLDGS INC COM 74736L109 18,905 184,295 SH   DFND 1 184,295 0 0
Q2 HLDGS INC COM 74736L109 5,490 53,516 SH   OTR 2 53,516 0 0
QIAGEN NV SHS NEW N72482123 17,735 366,569 SH   DFND 1 366,569 0 0
QTS RLTY TR INC COM CL A 74736A103 9,310 120,449 SH   DFND 1 120,449 0 0
QTS RLTY TR INC COM CL A 74736A103 2,653 34,317 SH   OTR 2 34,317 0 0
QUALCOMM INC COM 747525103 99,209 694,106 SH   DFND 1 684,209 0 9,897
QUANEX BLDG PRODS CORP COM 747619104 848 34,123 SH   DFND 1 34,123 0 0
QUANTA SVCS INC COM 74762E102 65,578 724,061 SH   DFND 1 721,245 0 2,816
RALPH LAUREN CORP CL A 751212101 17,643 149,754 SH   DFND 1 149,754 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 110,924 1,300,246 SH   DFND 1 1,300,246 0 0
REDWOOD TR INC COM 758075402 1,160 96,096 SH   DFND 1 96,096 0 0
RENAISSANCERE HLDGS LTD COM G7496G103 47,977 322,386 SH   DFND 1 322,386 0 0
RENEWABLE ENERGY GROUP INC COM NEW 75972A301 953 15,295 SH   DFND 1 15,295 0 0
REPLIGEN CORP COM 759916109 16,495 82,634 SH   DFND 1 82,634 0 0
RETAIL OPPORTUNITY INVTS COR COM 76131N101 18,323 1,037,532 SH   DFND 1 1,037,532 0 0
RETAIL OPPORTUNITY INVTS COR COM 76131N101 2,820 159,709 SH   OTR 2 159,709 0 0
RETAIL PPTYS AMER INC CL A 76131V202 1,627 142,108 SH   DFND 1 142,108 0 0
REVANCE THERAPEUTICS INC COM 761330109 53,670 1,810,729 SH   DFND 1 1,810,729 0 0
REVANCE THERAPEUTICS INC COM 761330109 3,908 131,851 SH   OTR 2 131,851 0 0
REXNORD CORP COM 76169B102 66,100 1,320,948 SH   DFND 1 1,320,948 0 0
REXNORD CORP COM 76169B102 9,084 181,534 SH   OTR 2 181,534 0 0
RICE ACQUISITION CORP COM CL A 762594109 3,527 195,402 SH   DFND 1 195,280 0 122
RINGCENTRAL INC CL A 76680R206 604,485 2,080,271 SH   DFND 1 1,963,067 0 117,204
RINGCENTRAL INC CL A 76680R206 8,244 28,372 SH   OTR 2 28,372 0 0
ROBLOX CORP CL A 771049103 557,767 6,198,783 SH   DFND 1 5,934,929 0 263,854
ROBLOX CORP CL A 771049103 9,756 108,427 SH   OTR 2 108,427 0 0
ROCKWELL AUTOMATION INC COM 773903109 4,615 16,134 SH   DFND 1 16,134 0 0
ROKU INC COM CL A 77543R102 16,545 36,027 SH   DFND 1 35,620 0 407
ROSS STORES INC COM 778296103 120,827 974,410 SH   DFND 1 974,410 0 0
ROYAL CARIBBEAN GROUP COM V7780T103 92,015 1,078,974 SH   DFND 1 1,078,974 0 0
ROYAL DUTCH SHELL PLC SPONS ADR A 780259206 15,937 394,471 SH   DFND 1 394,169 0 302
ROYAL GOLD INC COM 780287108 14,778 129,518 SH   DFND 1 129,518 0 0
RUSH ENTERPRISES INC CL A 781846209 25,463 588,880 SH   DFND 1 588,880 0 0
RUSH ENTERPRISES INC CL A 781846209 3,843 88,869 SH   OTR 2 88,869 0 0
RUSH STREET INTERACTIVE INC COM 782011100 17,321 1,412,804 SH   DFND 1 1,412,804 0 0
RUSH STREET INTERACTIVE INC COM 782011100 2,321 189,293 SH   OTR 2 189,293 0 0
S&P GLOBAL INC COM 78409V104 726,904 1,770,992 SH   DFND 1 1,633,355 0 137,637
S&P GLOBAL INC COM 78409V104 12,417 30,252 SH   OTR 2 30,252 0 0
SAGE THERAPEUTICS INC COM 78667J108 33,070 582,120 SH   DFND 1 582,120 0 0
SAIA INC COM 78709Y105 72,621 346,660 SH   DFND 1 346,660 0 0
SAIA INC COM 78709Y105 9,955 47,518 SH   OTR 2 47,518 0 0
SALESFORCE COM INC COM 79466L302 2,015,001 8,249,073 SH   DFND 1 7,696,619 0 552,454
SALESFORCE COM INC COM 79466L302 27,012 110,583 SH   OTR 2 110,583 0 0
SAREPTA THERAPEUTICS INC COM 803607100 4,830 62,129 SH   DFND 1 62,129 0 0
SBA COMMUNICATIONS CORP NEW CL A 78410G104 48,801 153,125 SH   DFND 1 142,908 0 10,217
SCHLUMBERGER LTD COM STK 806857108 9,931 310,253 SH   DFND 1 310,032 0 221
SCRIPPS E W CO OHIO CL A NEW 811054402 1,186 58,179 SH   DFND 1 58,179 0 0
SEA LTD SPONSORD ADS 81141R100 1,115,122 4,060,898 SH   DFND 1 3,777,630 0 283,268
SEA LTD SPONSORD ADS 81141R100 62,428 227,341 SH   OTR 2 227,341 0 0
SEACOAST BKG CORP FLA COM NEW 811707801 686 20,078 SH   DFND 1 20,078 0 0
SELECT MED HLDGS CORP COM 81619Q105 2,854 67,534 SH   DFND 1 67,534 0 0
SELECT SECTOR SPDR TR ENERGY 81369Y506 693 12,866 SH   DFND 1 12,727 0 139
SEMPRA ENERGY COM 816851109 92,338 696,993 SH   DFND 1 675,551 0 21,442
SERVICE CORP INTL COM 817565104 13,450 250,977 SH   DFND 1 250,977 0 0
SHIFT4 PMTS INC CL A 82452J109 46,776 499,108 SH   DFND 1 496,158 0 2,950
SHOALS TECHNOLOGIES GROUP IN CL A 82489W107 3,917 110,335 SH   DFND 1 110,251 0 84
SHOCKWAVE MED INC COM 82489T104 54,944 289,588 SH   DFND 1 289,588 0 0
SHOPIFY INC CL A 82509L107 6,594,489 4,513,743 SH   DFND 1 4,344,637 0 169,106
SHOPIFY INC CL A 82509L107 148,257 101,478 SH   OTR 2 101,478 0 0
SIBANYE STILLWATER LTD SPONSORED ADR 82575P107 2,895 173,018 SH   DFND 1 172,921 0 97
SILK RD MED INC COM 82710M100 8,396 175,427 SH   DFND 1 175,427 0 0
SILK RD MED INC COM 82710M100 2,113 44,150 SH   OTR 2 44,150 0 0
SILVERGATE CAP CORP CL A 82837P408 23,870 210,645 SH   DFND 1 210,645 0 0
SILVERGATE CAP CORP CL A 82837P408 3,419 30,170 SH   OTR 2 30,170 0 0
SITE CTRS CORP COM 82981J109 1,631 108,322 SH   DFND 1 108,322 0 0
SITEONE LANDSCAPE SUPPLY INC COM 82982L103 271 1,599 SH   DFND 1 1,599 0 0
SIX FLAGS ENTMT CORP NEW COM 83001A102 461 10,658 SH   DFND 1 10,658 0 0
SLM CORP COM 78442P106 109,046 5,207,528 SH   DFND 1 5,207,528 0 0
SMARTSHEET INC COM CL A 83200N103 24,758 342,343 SH   DFND 1 342,343 0 0
SMITH & WESSON BRANDS INC COM 831754106 1,997 57,544 SH   DFND 1 57,544 0 0
SNAP INC CL A 83304A106 2,730,084 40,065,815 SH   DFND 1 37,915,588 0 2,150,227
SNAP INC CL A 83304A106 77,604 1,138,886 SH   OTR 2 1,138,886 0 0
SNOWFLAKE INC CL A 833445109 624,909 2,584,404 SH   DFND 1 2,441,831 0 142,573
SNOWFLAKE INC CL A 833445109 9,182 37,975 SH   OTR 2 37,975 0 0
SOUTHERN CO COM 842587107 32,850 542,886 SH   DFND 1 542,886 0 0
SOUTHERN COPPER CORP COM 84265V105 10,230 159,041 SH   DFND 1 158,926 0 115
SOUTHWEST AIRLS CO COM 844741108 1,201 22,617 SH   DFND 1 22,617 0 0
SPDR SER TR S&P METALS MNG 78464A755 5,695 132,260 SH   DFND 1 130,837 0 1,423
SPOTIFY TECHNOLOGY S A SHS L8681T102 1,182,529 4,290,901 SH   DFND 1 4,165,460 0 125,441
SPOTIFY TECHNOLOGY S A SHS L8681T102 17,730 64,333 SH   OTR 2 64,333 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 25,849 313,659 SH   DFND 1 313,659 0 0
SPROUT SOCIAL INC COM CL A 85209W109 24,673 275,924 SH   DFND 1 275,924 0 0
SPROUT SOCIAL INC COM CL A 85209W109 4,733 52,925 SH   OTR 2 52,925 0 0
SPROUTS FMRS MKT INC COM 85208M102 20,592 828,664 SH   DFND 1 828,664 0 0
SPROUTS FMRS MKT INC COM 85208M102 2,389 96,139 SH   OTR 2 96,139 0 0
SQUARE INC CL A 852234103 2,533,675 10,392,431 SH   DFND 1 9,887,166 0 505,265
SQUARE INC CL A 852234103 69,925 286,814 SH   OTR 2 286,814 0 0
STAMPS COM INC COM NEW 852857200 36,441 181,943 SH   DFND 1 181,943 0 0
STAMPS COM INC COM NEW 852857200 4,925 24,588 SH   OTR 2 24,588 0 0
STARWOOD PPTY TR INC COM 85571B105 20,182 771,190 SH   DFND 1 771,190 0 0
STEEL DYNAMICS INC COM 858119100 20,236 339,527 SH   DFND 1 339,336 0 191
STRYKER CORPORATION COM 863667101 8,327 32,062 SH   DFND 1 32,062 0 0
SUMMIT HOTEL PPTYS INC COM 866082100 22,712 2,434,241 SH   DFND 1 2,434,241 0 0
SUMMIT HOTEL PPTYS INC COM 866082100 3,040 325,857 SH   OTR 2 325,857 0 0
SUMMIT MATLS INC CL A 86614U100 67,764 1,944,453 SH   DFND 1 1,944,453 0 0
SUMMIT MATLS INC CL A 86614U100 9,412 270,071 SH   OTR 2 270,071 0 0
SUN CTRY AIRLS HLDGS INC COM 866683105 17,625 476,227 SH   DFND 1 476,227 0 0
SUN CTRY AIRLS HLDGS INC COM 866683105 2,976 80,399 SH   OTR 2 80,399 0 0
SUNCOR ENERGY INC NEW COM 867224107 14,512 605,437 SH   DFND 1 604,956 0 481
SUNNOVA ENERGY INTL INC. COM 86745K104 13,606 361,281 SH   DFND 1 361,045 0 236
SUNRUN INC COM 86771W105 10,927 195,892 SH   DFND 1 195,755 0 137
SYKES ENTERPRISES INC COM 871237103 2,224 41,422 SH   DFND 1 41,422 0 0
SYNEOS HEALTH INC CL A 87166B102 23,383 261,294 SH   DFND 1 261,294 0 0
SYNEOS HEALTH INC CL A 87166B102 3,408 38,078 SH   OTR 2 38,078 0 0
SYSCO CORP COM 871829107 14,721 189,341 SH   DFND 1 189,341 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 1,498,560 12,471,375 SH   DFND 1 12,334,918 0 136,457
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 29,953 249,273 SH   OTR 2 249,273 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 22,964 129,724 SH   DFND 1 128,963 0 761
TALKSPACE INC COM 87427V103 27,554 3,425,763 SH   DFND 1 3,425,763 0 0
TALKSPACE INC COM 87427V103 2,259 271,840 SH   OTR 2 271,840 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 46,261 474,962 SH   DFND 1 474,962 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 5,650 58,007 SH   OTR 2 58,007 0 0
TARGA RES CORP COM 87612G101 201,370 4,530,254 SH   DFND 1 4,372,400 0 157,854
TARGET CORP COM 87612E106 1,109,517 4,589,715 SH   DFND 1 4,456,487 0 133,228
TARGET CORP COM 87612E106 23,570 97,500 SH   OTR 2 97,500 0 0
TC ENERGY CORP COM 87807B107 11,257 227,483 SH   DFND 1 181,179 0 46,304
TELADOC HEALTH INC COM 87918A105 156,981 944,021 SH   DFND 1 748,209 0 195,812
TELEDYNE TECHNOLOGIES INC COM 879360105 14,529 34,690 SH   DFND 1 34,294 0 396
TELEFLEX INCORPORATED COM 879369106 32,455 80,776 SH   DFND 1 80,208 0 568
TELUS INTL CDA INC SUB VTG SHS 87975H100 15,677 503,907 SH   DFND 1 503,907 0 0
TENABLE HLDGS INC COM 88025T102 1,106 26,738 SH   DFND 1 26,738 0 0
TENET HEALTHCARE CORP COM NEW 88033G407 1,495 22,324 SH   DFND 1 22,324 0 0
TERADATA CORP DEL COM 88076W103 1,859 37,197 SH   DFND 1 37,197 0 0
TESLA INC COM 88160R101 6,870,545 10,108,202 SH   DFND 1 9,626,348 0 481,854
TESLA INC COM 88160R101 152,396 224,211 SH   OTR 2 224,211 0 0
TEXAS INSTRS INC COM 882508104 248,846 1,294,052 SH   DFND 1 1,294,052 0 0
TEXAS ROADHOUSE INC COM 882681109 46,947 488,019 SH   DFND 1 485,409 0 2,610
TFI INTL INC COM 87241L109 40,824 447,688 SH   DFND 1 447,688 0 0
TFI INTL INC COM 87241L109 3,145 34,486 SH   OTR 2 34,486 0 0
THE BEAUTY HEALTH COMPANY COM CL A 88331L108 289 17,196 SH   DFND 1 17,196 0 0
THE TRADE DESK INC COM CL A 88339J105 1,076,588 13,916,599 SH   DFND 1 13,216,202 0 700,397
THE TRADE DESK INC COM CL A 88339J105 14,107 182,357 SH   OTR 2 182,357 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 73,096 144,897 SH   DFND 1 144,897 0 0
TIMKEN CO COM 887389104 884 10,969 SH   DFND 1 10,969 0 0
TJX COS INC NEW COM 872540109 1,287,426 19,095,600 SH   DFND 1 18,237,863 0 857,737
TJX COS INC NEW COM 872540109 18,541 275,011 SH   OTR 2 275,011 0 0
TOLL BROTHERS INC COM 889478103 16,547 286,233 SH   DFND 1 286,233 0 0
TOTALENERGIES SE SPONSORED ADS 89151E109 42,567 940,497 SH   DFND 1 940,212 0 285
TOWER SEMICONDUCTOR LTD SHS NEW M87915274 45,990 1,562,702 SH   DFND 1 1,562,702 0 0
TOWER SEMICONDUCTOR LTD SHS NEW M87915274 6,616 224,796 SH   OTR 2 224,796 0 0
TRANE TECHNOLOGIES PLC SHS G8994E103 47,753 259,329 SH   DFND 1 257,852 0 1,477
TRANSOCEAN LTD REG SHS H8817H100 960 212,389 SH   DFND 1 212,389 0 0
TREACE MED CONCEPTS INC COM 89455T109 16,221 518,906 SH   DFND 1 518,906 0 0
TREACE MED CONCEPTS INC COM 89455T109 1,305 41,746 SH   OTR 2 41,746 0 0
TRI POINTE HOMES INC COM 87265H109 900 41,979 SH   DFND 1 41,979 0 0
TRINET GROUP INC COM 896288107 1,383 19,088 SH   DFND 1 19,088 0 0
TRINITY INDS INC COM 896522109 24,574 913,852 SH   DFND 1 913,852 0 0
TRINITY INDS INC COM 896522109 4,773 177,518 SH   OTR 2 177,518 0 0
TRONOX HOLDINGS PLC SHS G9087Q102 1,038 46,341 SH   DFND 1 46,341 0 0
TRUIST FINL CORP COM 89832Q109 173,157 3,119,948 SH   DFND 1 3,119,948 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 55,811 715,345 SH   DFND 1 715,345 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 3,005 38,515 SH   OTR 2 38,515 0 0
TWILIO INC CL A 90138F102 2,617,566 6,640,872 SH   DFND 1 6,331,968 0 308,904
TWILIO INC CL A 90138F102 48,812 123,839 SH   OTR 2 123,839 0 0
TWIST BIOSCIENCE CORP COM 90184D100 1,057 7,936 SH   DFND 1 7,936 0 0
UBER TECHNOLOGIES INC COM 90353T100 2,243,039 44,753,373 SH   DFND 1 42,880,089 0 1,873,284
UBER TECHNOLOGIES INC COM 90353T100 28,672 572,075 SH   OTR 2 572,075 0 0
UFP INDUSTRIES INC COM 90278Q108 1,718 23,110 SH   DFND 1 23,110 0 0
UMB FINL CORP COM 902788108 2,193 23,565 SH   DFND 1 23,565 0 0
UMH PPTYS INC COM 903002103 12,818 587,438 SH   DFND 1 587,438 0 0
UMH PPTYS INC COM 903002103 3,681 168,683 SH   OTR 2 168,683 0 0
UNION PAC CORP COM 907818108 962,053 4,374,361 SH   DFND 1 4,091,075 0 283,286
UNION PAC CORP COM 907818108 15,419 70,109 SH   OTR 2 70,109 0 0
UNITED PARCEL SERVICE INC CL B 911312106 30,897 148,564 SH   DFND 1 148,564 0 0
UNITED RENTALS INC COM 911363109 73,908 231,680 SH   DFND 1 231,680 0 0
UNITEDHEALTH GROUP INC COM 91324P102 768,309 1,918,661 SH   DFND 1 1,862,765 0 55,896
UNITEDHEALTH GROUP INC COM 91324P102 11,635 29,056 SH   OTR 2 29,056 0 0
UNIVERSAL DISPLAY CORP COM 91347P105 62,793 282,433 SH   DFND 1 281,548 0 885
UPWORK INC COM 91688F104 1,222 20,963 SH   DFND 1 20,963 0 0
URBAN EDGE PPTYS COM 91704F104 2,370 124,099 SH   DFND 1 124,099 0 0
UTZ BRANDS INC COM CL A 918090101 12,089 554,780 SH   DFND 1 554,780 0 0
UTZ BRANDS INC COM CL A 918090101 3,099 142,241 SH   OTR 2 142,241 0 0
VALE S A SPONSORED ADS 91912E105 14,269 625,570 SH   DFND 1 625,035 0 535
VALERO ENERGY CORP COM 91913Y100 14,928 191,187 SH   DFND 1 191,109 0 78
VALLEY NATL BANCORP COM 919794107 1,425 106,131 SH   DFND 1 106,131 0 0
VARONIS SYS INC COM 922280102 51,015 885,366 SH   DFND 1 885,366 0 0
VARONIS SYS INC COM 922280102 8,846 153,520 SH   OTR 2 153,520 0 0
VERACYTE INC COM 92337F107 16,036 401,085 SH   DFND 1 401,085 0 0
VERACYTE INC COM 92337F107 2,373 59,360 SH   OTR 2 59,360 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 159,656 791,828 SH   DFND 1 671,252 0 120,576
VERVE THERAPEUTICS INC COM 92539P101 22,293 370,000 SH   DFND 1 370,000 0 0
VIATRIS INC COM 92556V106 29,939 2,095,106 SH   DFND 1 2,095,106 0 0
VIMEO INC COMMON STOCK 92719V100 27,417 559,532 SH   DFND 1 557,631 0 1,901
VISA INC COM CL A 92826C839 2,996,114 12,813,763 SH   DFND 1 12,245,072 0 568,691
VISA INC COM CL A 92826C839 41,292 176,597 SH   OTR 2 176,597 0 0
VISTA OUTDOOR INC COM 928377100 1,096 23,678 SH   DFND 1 23,678 0 0
VROOM INC COM 92918V109 23,555 562,722 SH   DFND 1 562,722 0 0
VROOM INC COM 92918V109 3,465 82,768 SH   OTR 2 82,768 0 0
WABTEC COM 929740108 11,482 139,513 SH   DFND 1 139,513 0 0
WALMART INC COM 931142103 204,066 1,447,071 SH   DFND 1 1,435,704 0 11,367
WASTE CONNECTIONS INC COM 94106B101 2,255 18,880 SH   DFND 1 4,513 0 14,367
WATERS CORP COM 941848103 1,640 4,745 SH   DFND 1 4,745 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 1,581 4,403 SH   DFND 1 4,403 0 0
WESTERN MIDSTREAM PARTNERS L COM UNIT LP INT 958669103 28,401 1,325,902 SH   DFND 1 1,325,902 0 0
WESTERN UN CO COM 959802109 3,735 162,598 SH   DFND 1 162,598 0 0
WESTLAKE CHEM CORP COM 960413102 11,960 132,760 SH   DFND 1 132,760 0 0
WEX INC COM 96208T104 60,626 312,666 SH   DFND 1 311,568 0 1,098
WHEATON PRECIOUS METALS CORP COM 962879102 5,508 124,982 SH   DFND 1 124,878 0 104
WILLIAMS COS INC COM 969457100 211,128 7,952,081 SH   DFND 1 7,765,140 0 186,941
WILLSCOT MOBIL MINI HLDNG CO COM CL A 971378104 81,937 2,939,978 SH   DFND 1 2,939,978 0 0
WILLSCOT MOBIL MINI HLDNG CO COM CL A 971378104 11,349 407,217 SH   OTR 2 407,217 0 0
WINGSTOP INC COM 974155103 29,128 184,786 SH   DFND 1 184,786 0 0
WINGSTOP INC COM 974155103 7,556 47,934 SH   OTR 2 47,934 0 0
WINTRUST FINL CORP COM 97650W108 40,169 531,125 SH   DFND 1 531,125 0 0
WINTRUST FINL CORP COM 97650W108 5,417 71,620 SH   OTR 2 71,620 0 0
WIX COM LTD SHS M98068105 211,494 728,587 SH   DFND 1 728,587 0 0
WIX COM LTD SHS M98068105 2,816 9,700 SH   OTR 2 9,700 0 0
WORKDAY INC CL A 98138H101 884,814 3,706,179 SH   DFND 1 3,485,995 0 220,184
WORKDAY INC CL A 98138H101 10,052 42,106 SH   OTR 2 42,106 0 0
WSFS FINL CORP COM 929328102 22,814 489,674 SH   DFND 1 489,674 0 0
WSFS FINL CORP COM 929328102 3,407 73,138 SH   OTR 2 73,138 0 0
XCEL ENERGY INC COM 98389B100 53,844 817,307 SH   DFND 1 817,307 0 0
XOMETRY INC CLASS A COM 98423F109 5,242 59,991 SH   DFND 1 59,991 0 0
XOMETRY INC CLASS A COM 98423F109 875 10,009 SH   OTR 2 10,009 0 0
YETI HLDGS INC COM 98585X104 31,241 340,245 SH   DFND 1 337,957 0 2,288
YUM BRANDS INC COM 988498101 3,565 30,995 SH   DFND 1 30,995 0 0
ZAI LAB LTD ADR 98887Q104 244,240 1,379,966 SH   DFND 1 1,379,479 0 487
ZEBRA TECHNOLOGIES CORPORATI CL A 989207105 1,655 3,125 SH   DFND 1 3,125 0 0
ZENDESK INC COM 98936J101 37,190 257,653 SH   DFND 1 256,225 0 1,428
ZILLOW GROUP INC CL C CAP STK 98954M200 443 3,621 SH   DFND 1 3,621 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 214,330 1,332,730 SH   DFND 1 1,332,730 0 0
ZOETIS INC CL A 98978V103 8,715 46,763 SH   DFND 1 0 0 46,763
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 271,698 702,006 SH   DFND 1 651,987 0 50,019
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 13,522 34,939 SH   OTR 2 34,939 0 0
ZUMIEZ INC COM 989817101 2,194 44,784 SH   DFND 1 44,784 0 0