The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACV AUCTIONS INC COM CL A 00091G104 7,064 204,100 SH   DFND 1, 2 204,100 0 0
AES CORP COM 00130H105 1,426,075 53,191,902 SH   DFND 1, 2 53,191,902 0 0
AES CORP UNIT 99/99/9999 00130H204 114,560 1,109,000 SH   DFND 1, 2 1,109,000 0 0
AT&T INC COM 00206R102 211,890 7,000,000 SH   DFND 1, 2 7,000,000 0 0
ABBOTT LABS COM 002824100 456,421 3,808,597 SH   DFND 1, 2 3,797,862 0 10,735
ABCELLERA BIOLOGICS INC COM 00288U106 141,303 4,160,870 SH   DFND 1, 2 4,160,870 0 0
ACTIVISION BLIZZARD INC COM 00507V109 2,387,898 25,676,348 SH   DFND 1, 2 25,670,621 0 5,727
ACUTUS MED INC COM 005111109 28,317 2,117,967 SH   DFND 1, 2 2,117,967 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 42,494 8,002,700 SH   DFND 1, 2 8,002,700 0 0
ADDUS HOMECARE CORP COM 006739106 84,049 803,600 SH   DFND 1, 2 803,600 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 1,175,664 2,473,230 SH   DFND 1, 2 2,469,678 0 3,552
ADVANCED MICRO DEVICES INC COM 007903107 3,548,037 45,198,314 SH   DFND 1, 2 45,186,240 0 12,074
AFFIRM HLDGS INC COM CL A 00827B106 15,912 225,005 SH   DFND 1, 2 225,000 0 5
AGORA INC ADS 00851L103 65,602 1,305,000 SH   DFND 1, 2 1,305,000 0 0
AIRBNB INC COM CL A 009066101 479,365 2,550,629 SH   DFND 1, 2 2,550,629 0 0
AIR PRODS & CHEMS INC COM 009158106 457,375 1,625,677 SH   DFND 1, 2 1,620,357 0 5,320
ALARM COM HLDGS INC COM 011642105 122,746 1,421,000 SH   DFND 1, 2 1,421,000 0 0
ALCOA CORP COM 013872106 29,566 910,000 SH   DFND 1, 2 910,000 0 0
ALEXANDRIA REAL ESTATE EQ IN COM 015271109 562,021 3,420,700 SH   DFND 1, 2 3,420,700 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 2,602 11,349 SH   DFND 1, 2 5 0 11,344
ALIGN TECHNOLOGY INC COM 016255101 12,131 22,402 SH   DFND 1, 2 22,402 0 0
ALIGNMENT HEALTHCARE INC COM 01625V104 76,755 3,500,000 SH   DFND 1, 2 3,500,000 0 0
ALLAKOS INC COM 01671P100 746,854 6,506,829 SH   DFND 1, 2 6,506,829 0 0
ALLEGHENY TECHNOLOGIES INC COM 01741R102 54,534 2,589,437 SH   DFND 1, 2 2,589,437 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 79,305 2,246,603 SH   DFND 1, 2 2,246,603 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 49,776 352,546 SH   DFND 1, 2 352,546 0 0
ALPHABET INC CAP STK CL C 02079K107 5,577,909 2,696,438 SH   DFND 1, 2 2,694,658 0 1,780
ALPHABET INC CAP STK CL A 02079K305 3,716,280 1,801,856 SH   DFND 1, 2 1,796,625 0 5,231
ALTIMMUNE INC COM NEW 02155H200 19,839 1,404,000 SH   DFND 1, 2 1,404,000 0 0
ALTERYX INC COM CL A 02156B103 425,068 5,123,769 SH   DFND 1, 2 5,123,769 0 0
ALTICE USA INC CL A 02156K103 33,301 1,023,700 SH   DFND 1, 2 1,023,700 0 0
ALTRIA GROUP INC COM 02209S103 6,373,098 124,571,895 SH   DFND 1, 2 124,571,895 0 0
AMAZON COM INC COM 023135106 9,671,073 3,125,697 SH   DFND 1, 2 3,123,549 0 2,148
AMERICA MOVIL SAB DE CV SPON ADR L SHS 02364W105 18,088 1,331,703 SH   DFND 1, 2 1,315,387 0 16,316
AMERICAN AIRLS GROUP INC NOTE 6.500% 7/0 02376RAF9 6,258 3,633,000 PRN   DFND 1, 2 3,633,000 0 0
AMERICAN ELEC PWR CO INC COM 025537101 676,784 7,990,369 SH   DFND 1, 2 7,990,369 0 0
AMERICAN ELEC PWR CO INC UNIT 08/01/2021 025537127 1,834 38,000 SH   DFND 1, 2 38,000 0 0
AMERICAN ELEC PWR CO INC UNIT 08/15/2025 02557T307 37,913 775,951 SH   DFND 1, 2 775,951 0 0
AMERICAN TOWER CORP NEW COM 03027X100 1,353,362 5,661,194 SH   DFND 1, 2 5,659,428 0 1,766
AMERICAN WELL CORP CL A 03044L105 22,477 1,294,000 SH   DFND 1, 2 1,294,000 0 0
AMPHENOL CORP NEW CL A 032095101 60,882 922,881 SH   DFND 1, 2 922,881 0 0
ANALOG DEVICES INC COM 032654105 366,499 2,363,290 SH   DFND 1, 2 2,363,290 0 0
APA CORPORATION COM 03743Q108 44,367 2,478,584 SH   DFND 1, 2 2,478,500 0 84
APOLLO GLOBAL MGMT INC COM CL A 03768E105 578,096 12,297,306 SH   DFND 1, 2 12,297,306 0 0
APPLE INC COM 037833100 2,655,449 21,739,774 SH   DFND 1, 2 21,711,425 0 28,349
APPFOLIO INC COM CL A 03783C100 37,168 262,842 SH   DFND 1, 2 262,842 0 0
APPLIED MATLS INC COM 038222105 2,716,596 20,333,800 SH   DFND 1, 2 20,333,791 0 9
APPLIED MOLECULAR TRANS INC COM 03824M109 120,125 2,729,485 SH   DFND 1, 2 2,729,485 0 0
ARAMARK COM 03852U106 114,792 3,038,421 SH   DFND 1, 2 3,038,421 0 0
ARCHER DANIELS MIDLAND CO COM 039483102 1,676,899 29,419,289 SH   DFND 1, 2 29,419,289 0 0
ARCOSA INC COM 039653100 72,575 1,115,000 SH   DFND 1, 2 1,115,000 0 0
ARES MANAGEMENT CORPORATION CL A COM STK 03990B101 572,332 10,214,738 SH   DFND 1, 2 10,214,738 0 0
ARGENX SE SPONSORED ADR 04016X101 182,313 662,019 SH   DFND 1, 2 662,019 0 0
ARISTA NETWORKS INC COM 040413106 960,584 3,181,900 SH   DFND 1, 2 3,181,897 0 3
ARMSTRONG WORLD INDS INC NEW COM 04247X102 55,252 613,300 SH   DFND 1, 2 613,300 0 0
ARTISAN PARTNERS ASSET MGMT CL A 04316A108 36,780 705,000 SH   DFND 1, 2 705,000 0 0
ASSETMARK FINL HLDGS INC COM 04546L106 31,509 1,350,000 SH   DFND 1, 2 1,350,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 231,063 4,646,798 SH   DFND 1, 2 4,551,276 0 95,522
AUTODESK INC COM 052769106 1,115,251 4,024,112 SH   DFND 1, 2 4,020,454 0 3,658
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 16,937 2,955,806 SH   DFND 1, 2 2,955,806 0 0
AUTOMATIC DATA PROCESSING IN COM 053015103 862,618 4,576,953 SH   DFND 1, 2 4,576,953 0 0
BCE INC COM NEW 05534B760 339 7,500 SH   DFND 1, 2 7,500 0 0
BAKER HUGHES COMPANY CL A 05722G100 1,795,430 83,082,611 SH   DFND 1, 2 82,961,874 0 120,737
BALL CORP COM 058498106 106,798 1,260,307 SH   DFND 1, 2 1,260,307 0 0
BANDWIDTH INC COM CL A 05988J103 104,197 822,134 SH   DFND 1, 2 822,134 0 0
BK OF AMERICA CORP COM 060505104 4,578,038 118,326,139 SH   DFND 1, 2 118,326,139 0 0
BANK NOVA SCOTIA B C COM 064149107 1,276,599 20,407,290 SH   DFND 1, 2 20,407,290 0 0
BARRICK GOLD CORP COM 067901108 940,315 47,477,885 SH   DFND 1, 2 47,477,885 0 0
BARRETT BUSINESS SVCS INC COM 068463108 42,057 610,765 SH   DFND 1, 2 610,765 0 0
BAUSCH HEALTH COS INC COM 071734107 30,199 951,447 SH   DFND 1, 2 951,447 0 0
BAXTER INTL INC COM 071813109 813,359 9,643,813 SH   DFND 1, 2 9,643,813 0 0
BEAZER HOMES USA INC COM NEW 07556Q881 34,723 1,659,813 SH   DFND 1, 2 1,659,813 0 0
BERKLEY W R CORP COM 084423102 90,698 1,203,691 SH   DFND 1, 2 1,203,677 0 14
BERKSHIRE HATHAWAY INC DEL CL A 084670108 64,027 166 SH   DFND 1, 2 166 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 261,367 1,023,082 SH   DFND 1, 2 1,023,082 0 0
BEYOND MEAT INC COM 08862E109 12,348 94,895 SH   DFND 1, 2 94,895 0 0
BIOGEN INC COM 09062X103 92,595 330,992 SH   DFND 1, 2 330,992 0 0
BIONTECH SE SPONSORED ADS 09075V102 47,266 432,882 SH   DFND 1, 2 432,879 0 3
BLACK DIAMOND THERAPEUTICS I COM 09203E105 12,737 525,000 SH   DFND 1, 2 525,000 0 0
BLACK KNIGHT INC COM 09215C105 8,731 118,000 SH   DFND 1, 2 118,000 0 0
BLACKLINE INC COM 09239B109 64,498 595,000 SH   DFND 1, 2 595,000 0 0
BLACKROCK INC COM 09247X101 5,664,166 7,512,612 SH   DFND 1, 2 7,503,581 0 9,031
BLACKSTONE GROUP INC COM 09260D107 1,290,550 17,315,852 SH   DFND 1, 2 17,315,852 0 0
BOEING CO COM 097023105 1,578,427 6,196,714 SH   DFND 1, 2 6,196,698 0 16
BOOKING HOLDINGS INC COM 09857L108 2,549,453 1,094,261 SH   DFND 1, 2 1,094,260 0 1
BOSTON PROPERTIES INC COM 101121101 4,086 40,000 SH   DFND 1, 2 40,000 0 0
BOSTON SCIENTIFIC CORP COM 101137107 163,654 4,234,258 SH   DFND 1, 2 4,233,986 0 272
BOTTOMLINE TECH DEL INC COM 101388106 212,160 4,688,617 SH   DFND 1, 2 4,688,617 0 0
BRIGHT HORIZONS FAM SOL IN D COM 109194100 550,883 3,213,081 SH   DFND 1, 2 3,213,076 0 5
BRISTOL-MYERS SQUIBB CO COM 110122108 678,774 10,752,010 SH   DFND 1, 2 10,752,010 0 0
BRITISH AMERN TOB PLC SPONSORED ADR 110448107 258,874 6,682,906 SH   DFND 1, 2 6,603,514 0 79,392
BROADCOM INC COM 11135F101 18,105,565 39,049,787 SH   DFND 1, 2 39,015,359 0 34,428
BROOKFIELD ASSET MGMT INC CL A LTD VT SH 112585104 650,272 14,612,205 SH   DFND 1, 2 14,555,924 0 56,281
BROOKFIELD INFRASTRUCTURE CO COM SB VTG SHS A 11275Q107 3,991 52,162 SH   DFND 1, 2 52,162 0 0
BUILDERS FIRSTSOURCE INC COM 12008R107 35,252 760,228 SH   DFND 1, 2 760,228 0 0
BUMBLE INC COM CL A 12047B105 355,404 5,697,398 SH   DFND 1, 2 5,697,398 0 0
BURLINGTON STORES INC COM 122017106 422,405 1,413,673 SH   DFND 1, 2 1,413,673 0 0
CDW CORP COM 12514G108 107,739 650,008 SH   DFND 1, 2 650,000 0 8
CF INDS HLDGS INC COM 125269100 228,284 5,030,491 SH   DFND 1, 2 5,030,453 0 38
CIGNA CORP NEW COM 125523100 3,676,216 15,207,040 SH   DFND 1, 2 15,190,692 0 16,348
CME GROUP INC COM 12572Q105 6,893,790 33,755,011 SH   DFND 1, 2 33,748,839 0 6,172
CMS ENERGY CORP COM 125896100 442,877 7,234,409 SH   DFND 1, 2 7,165,678 0 68,731
CSX CORP COM 126408103 6,538,052 67,808,068 SH   DFND 1, 2 67,764,640 0 43,428
CVS HEALTH CORP COM 126650100 2,797,695 37,188,058 SH   DFND 1, 2 37,144,431 0 43,627
CABOT OIL & GAS CORP COM 127097103 518,797 27,624,948 SH   DFND 1, 2 27,624,948 0 0
CAESARS ENTERTAINMENT INC NE COM 12769G100 403,067 4,609,115 SH   DFND 1, 2 4,609,115 0 0
CALIFORNIA RES CORP COM STOCK 13057Q305 7,340 305,059 SH   DFND 1, 2 305,059 0 0
CAMDEN PPTY TR SH BEN INT 133131102 283,599 2,580,285 SH   DFND 1, 2 2,580,285 0 0
CANADIAN NAT RES LTD COM 136385101 2,405,558 77,813,989 SH   DFND 1, 2 77,786,803 0 27,186
CANNAE HLDGS INC COM 13765N107 57,151 1,442,473 SH   DFND 1, 2 1,442,473 0 0
CAPITAL ONE FINL CORP COM 14040H105 2,826,075 22,211,767 SH   DFND 1, 2 22,157,945 0 53,822
CARLYLE GROUP INC COM 14316J108 639,227 17,389,211 SH   DFND 1, 2 17,389,211 0 0
CARRIER GLOBAL CORPORATION COM 14448C104 1,207,459 28,599,222 SH   DFND 1, 2 28,599,222 0 0
CARVANA CO CL A 146869102 245,666 936,229 SH   DFND 1, 2 936,229 0 0
CATALENT INC COM 148806102 685,765 6,511,866 SH   DFND 1, 2 6,511,866 0 0
CATERPILLAR INC COM 149123101 2,821,422 12,168,006 SH   DFND 1, 2 12,146,563 0 21,443
CAVCO INDS INC DEL COM 149568107 38,550 170,870 SH   DFND 1, 2 170,870 0 0
CELLECTIS S A SPON ADS 15117K103 17,684 875,000 SH   DFND 1, 2 875,000 0 0
CENTENE CORP DEL COM 15135B101 2,279,351 35,665,011 SH   DFND 1, 2 35,665,011 0 0
CENOVUS ENERGY INC COM 15135U109 96,140 12,798,618 SH   DFND 1, 2 12,798,618 0 0
CENTURY CMNTYS INC COM 156504300 54,952 911,000 SH   DFND 1, 2 911,000 0 0
CERIDIAN HCM HLDG INC COM 15677J108 847,502 10,056,985 SH   DFND 1, 2 10,056,985 0 0
CERTARA INC COM 15687V109 18,697 684,863 SH   DFND 1, 2 684,863 0 0
CHART INDS INC COM 16115Q308 50,465 354,512 SH   DFND 1, 2 354,512 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 1,315,691 2,132,332 SH   DFND 1, 2 2,132,332 0 0
CHEMED CORP NEW COM 16359R103 116,600 253,577 SH   DFND 1, 2 253,575 0 2
CHESAPEAKE ENERGY CORP *W EXP 99/99/999 165167164 8,570 492,820 SH   DFND 1, 2 492,820 0 0
CHESAPEAKE ENERGY CORP *W EXP 99/99/999 165167172 11,576 586,432 SH   DFND 1, 2 586,432 0 0
CHESAPEAKE ENERGY CORP *W EXP 03/01/202 165167180 3,036 180,691 SH   DFND 1, 2 180,691 0 0
CHESAPEAKE ENERGY CORP COM 165167735 258,099 5,951,340 SH   DFND 1, 2 5,951,340 0 0
CHEVRON CORP NEW COM 166764100 2,123,593 20,264,996 SH   DFND 1, 2 20,243,748 0 21,248
CHINDATA GROUP HLDGS LTD ADS 16955F107 119,196 7,206,548 SH   DFND 1, 2 7,206,548 0 0
CHIPOTLE MEXICAN GRILL INC COM 169656105 412,237 290,140 SH   DFND 1, 2 290,140 0 0
CIMAREX ENERGY CO COM 171798101 264,243 4,449,279 SH   DFND 1, 2 4,449,279 0 0
CINTAS CORP COM 172908105 205,707 602,698 SH   DFND 1, 2 602,698 0 0
CITIGROUP INC COM NEW 172967424 3,575,954 49,153,836 SH   DFND 1, 2 49,095,143 0 58,693
CLEAR CHANNEL OUTDOOR HLDGS COM 18453H106 1,879 1,043,695 SH   DFND 1, 2 1,043,695 0 0
CLOUDFLARE INC CL A COM 18915M107 174,673 2,486,091 SH   DFND 1, 2 2,486,091 0 0
COCA COLA CO COM 191216100 690,590 13,101,692 SH   DFND 1, 2 13,101,451 0 241
COLGATE PALMOLIVE CO COM 194162103 131,609 1,669,529 SH   DFND 1, 2 1,669,529 0 0
COMFORT SYS USA INC COM 199908104 94,605 1,265,279 SH   DFND 1, 2 1,265,279 0 0
COMCAST CORP NEW CL A 20030N101 6,077,439 112,314,144 SH   DFND 1, 2 112,176,184 0 137,960
CONAGRA BRANDS INC COM 205887102 2,151,909 57,230,268 SH   DFND 1, 2 57,160,265 0 70,003
CONOCOPHILLIPS COM 20825C104 849,336 16,034,287 SH   DFND 1, 2 16,034,287 0 0
CONSTELLATION BRANDS INC CL A 21036P108 1,106,711 4,853,996 SH   DFND 1, 2 4,853,996 0 0
COOPER TIRE & RUBR CO COM 216831107 34,484 616,000 SH   DFND 1, 2 616,000 0 0
COPART INC COM 217204106 543,669 5,005,704 SH   DFND 1, 2 5,005,693 0 11
CORTEVA INC COM 22052L104 462,744 9,925,864 SH   DFND 1, 2 9,925,864 0 0
CORTEXYME INC COM 22053A107 119,801 3,325,029 SH   DFND 1, 2 3,325,029 0 0
COSTCO WHSL CORP NEW COM 22160K105 1,393,389 3,953,172 SH   DFND 1, 2 3,944,188 0 8,984
COSTAR GROUP INC COM 22160N109 41,095 50,000 SH   DFND 1, 2 50,000 0 0
COUPANG INC CL A 22266T109 312,733 6,337,047 SH   DFND 1, 2 6,337,047 0 0
COVETRUS INC COM 22304C100 27,722 925,000 SH   DFND 1, 2 925,000 0 0
CRONOS GROUP INC COM 22717L101 10,730 1,135,000 SH   DFND 1, 2 1,135,000 0 0
CROWN CASTLE INTL CORP NEW COM 22822V101 3,302,011 19,183,242 SH   DFND 1, 2 19,183,242 0 0
CUMULUS MEDIA INC COM CL A 231082801 7,097 779,084 SH   DFND 1, 2 779,084 0 0
D R HORTON INC COM 23331A109 575,251 6,454,796 SH   DFND 1, 2 6,454,796 0 0
DTE ENERGY CO COM 233331107 2,651,085 19,912,011 SH   DFND 1, 2 19,912,011 0 0
DTE ENERGY CO UNIT 11/01/2022S 233331842 181,513 3,652,915 SH   DFND 1, 2 3,652,915 0 0
DADA NEXUS LTD ADS 23344D108 1,544 56,900 SH   DFND 1, 2 56,900 0 0
DANAHER CORPORATION COM 235851102 685,048 3,043,574 SH   DFND 1, 2 3,043,574 0 0
DANIMER SCIENTIFIC INC COM CL A 236272100 108,433 2,872,393 SH   DFND 1, 2 2,872,393 0 0
DARDEN RESTAURANTS INC COM 237194105 1,188,954 8,372,913 SH   DFND 1, 2 8,372,913 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 12,107 270,000 SH   DFND 1, 2 270,000 0 0
DEERE & CO COM 244199105 1,390,677 3,716,997 SH   DFND 1, 2 3,716,997 0 0
DELL TECHNOLOGIES INC CL C 24703L202 848,627 9,627,074 SH   DFND 1, 2 9,627,074 0 0
DELTA AIR LINES INC DEL COM NEW 247361702 1,359,351 28,155,582 SH   DFND 1, 2 28,155,582 0 0
DENBURY INC COM 24790A101 142,411 2,973,711 SH   DFND 1, 2 2,973,711 0 0
DEXCOM INC COM 252131107 471,899 1,313,056 SH   DFND 1, 2 1,313,054 0 2
DIAMONDBACK ENERGY INC COM 25278X109 185,620 2,525,791 SH   DFND 1, 2 2,525,791 0 0
DIEBOLD INC COM 253651103 9,679 685,000 SH   DFND 1, 2 685,000 0 0
DIGITAL RLTY TR INC COM 253868103 2,353,082 16,707,426 SH   DFND 1, 2 16,686,082 0 21,344
DISNEY WALT CO COM 254687106 663,078 3,593,527 SH   DFND 1, 2 3,593,527 0 0
DISCOVER FINL SVCS COM 254709108 826,627 8,702,142 SH   DFND 1, 2 8,664,499 0 37,643
DISH NETWORK CORPORATION NOTE 3.375% 8/1 25470MAB5 42,080 43,660,000 PRN   DFND 1, 2 43,660,000 0 0
DOCUSIGN INC COM 256163106 534,392 2,639,624 SH   DFND 1, 2 2,639,616 0 8
DOLBY LABORATORIES INC COM CL A 25659T107 67,441 683,154 SH   DFND 1, 2 683,144 0 10
DOLLAR GEN CORP NEW COM 256677105 2,655,136 13,104,018 SH   DFND 1, 2 13,104,012 0 6
DOMINION ENERGY INC COM 25746U109 152,522 2,007,925 SH   DFND 1, 2 2,007,925 0 0
DOMINION ENERGY INC UNIT 99/99/9999 25746U133 159,311 1,611,805 SH   DFND 1, 2 1,611,805 0 0
DOMINOS PIZZA INC COM 25754A201 1,738,106 4,725,810 SH   DFND 1, 2 4,725,810 0 0
DOUGLAS EMMETT INC COM 25960P109 149,150 4,750,000 SH   DFND 1, 2 4,750,000 0 0
DOW INC COM 260557103 3,457,870 54,079,211 SH   DFND 1, 2 54,011,394 0 67,817
DRAFTKINGS INC COM CL A 26142R104 86,291 1,407,000 SH   DFND 1, 2 1,407,000 0 0
DRIVEN BRANDS HLDGS INC COM 26210V102 27,715 1,090,300 SH   DFND 1, 2 1,090,300 0 0
DUKE ENERGY CORP NEW COM NEW 26441C204 357,161 3,700,000 SH   DFND 1, 2 3,700,000 0 0
DUN & BRADSTREET HLDGS INC COM 26484T106 324,789 13,640,855 SH   DFND 1, 2 13,640,855 0 0
EOG RES INC COM 26875P101 99,884 1,377,141 SH   DFND 1, 2 1,377,141 0 0
EASTMAN CHEM CO COM 277432100 1,147,936 10,424,407 SH   DFND 1, 2 10,424,407 0 0
EDITAS MEDICINE INC COM 28106W103 54,600 1,300,000 SH   DFND 1, 2 1,300,000 0 0
EMERSON ELEC CO COM 291011104 1,816,599 20,135,212 SH   DFND 1, 2 20,135,212 0 0
ENBRIDGE INC COM 29250N105 256,115 7,036,041 SH   DFND 1, 2 7,025,020 0 11,021
ENDAVA PLC ADS 29260V105 98,731 1,165,798 SH   DFND 1, 2 1,165,798 0 0
EPAM SYS INC COM 29414B104 1,058,566 2,668,496 SH   DFND 1, 2 2,668,496 0 0
EQUIFAX INC COM 294429105 31,441 173,582 SH   DFND 1, 2 173,582 0 0
EQUINIX INC COM 29444U700 1,268,893 1,867,145 SH   DFND 1, 2 1,867,145 0 0
ESSENTIAL UTILS INC UNIT 04/30/2022 29670G201 2,036 35,600 SH   DFND 1, 2 35,600 0 0
ETSY INC COM 29786A106 73,983 366,850 SH   DFND 1, 2 366,850 0 0
EXACT SCIENCES CORP COM 30063P105 1,107,978 8,407,786 SH   DFND 1, 2 8,407,786 0 0
EXTRA SPACE STORAGE INC COM 30225T102 216,526 1,633,545 SH   DFND 1, 2 1,633,545 0 0
EXTRACTION OIL & GAS INC COM 30227M303 63,669 1,841,370 SH   DFND 1, 2 1,841,370 0 0
EXXON MOBIL CORP COM 30231G102 1,043,473 18,690,189 SH   DFND 1, 2 18,690,175 0 14
FACEBOOK INC CL A 30303M102 12,756,994 43,313,543 SH   DFND 1, 2 43,291,568 0 21,975
FARFETCH LTD ORD SH CL A 30744W107 8,475 159,848 SH   DFND 1, 2 159,848 0 0
FEDEX CORP COM 31428X106 158,152 556,794 SH   DFND 1, 2 556,794 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 88,181 627,130 SH   DFND 1, 2 627,115 0 15
FIFTH THIRD BANCORP COM 316773100 695,777 18,578,818 SH   DFND 1, 2 18,578,818 0 0
FIRST REP BK SAN FRANCISCO C COM 33616C100 903,393 5,417,650 SH   DFND 1, 2 5,417,650 0 0
FIRSTSERVICE CORP NEW COM 33767E202 29,687 200,000 SH   DFND 1, 2 200,000 0 0
FISERV INC COM 337738108 666,811 5,601,574 SH   DFND 1, 2 5,601,574 0 0
FIVE BELOW INC COM 33829M101 314,002 1,645,797 SH   DFND 1, 2 1,645,797 0 0
FLEETCOR TECHNOLOGIES INC COM 339041105 1,149,067 4,277,508 SH   DFND 1, 2 4,277,508 0 0
FLOOR & DECOR HLDGS INC CL A 339750101 1,084,799 11,361,528 SH   DFND 1, 2 11,361,528 0 0
FOCUS FINL PARTNERS INC COM CL A 34417P100 106,089 2,549,002 SH   DFND 1, 2 2,549,002 0 0
FOX FACTORY HLDG CORP COM 35138V102 7,859 61,853 SH   DFND 1, 2 61,853 0 0
FRANCO NEV CORP COM 351858105 770,139 6,145,363 SH   DFND 1, 2 6,145,363 0 0
FRONTDOOR INC COM 35905A109 30,530 568,000 SH   DFND 1, 2 568,000 0 0
FULLER H B CO COM 359694106 27,051 430,000 SH   DFND 1, 2 430,000 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 60,900 280,774 SH   DFND 1, 2 280,774 0 0
GAMING & LEISURE PPTYS INC COM 36467J108 830,598 19,575,733 SH   DFND 1, 2 19,575,733 0 0
GENERAL ELECTRIC CO COM 369604103 76,055 5,792,461 SH   DFND 1, 2 5,792,461 0 0
GENERAL MLS INC COM 370334104 1,100,846 17,952,481 SH   DFND 1, 2 17,952,481 0 0
GENERAL MTRS CO COM 37045V100 4,755,204 82,754,767 SH   DFND 1, 2 82,645,812 0 108,955
GENETRON HLDGS LTD ADS 37186H100 53,053 2,472,191 SH   DFND 1, 2 2,472,191 0 0
GENTEX CORP COM 371901109 5,921 166,000 SH   DFND 1, 2 166,000 0 0
GILEAD SCIENCES INC COM 375558103 2,267,472 35,083,494 SH   DFND 1, 2 35,053,447 0 30,047
GLAUKOS CORP COM 377322102 62,975 750,322 SH   DFND 1, 2 750,322 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 59,348 1,456,390 SH   DFND 1, 2 1,456,390 0 0
GOLDMAN SACHS GROUP INC COM 38141G104 266,633 815,337 SH   DFND 1, 2 811,720 0 3,617
GRACO INC COM 384109104 68,325 954,000 SH   DFND 1, 2 954,000 0 0
GRAND CANYON ED INC COM 38526M106 53,550 500,000 SH   DFND 1, 2 500,000 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 231,177 13,370,578 SH   DFND 1, 2 13,370,578 0 0
GROCERY OUTLET HLDG CORP COM 39874R101 57,733 1,565,000 SH   DFND 1, 2 1,565,000 0 0
GUIDEWIRE SOFTWARE INC COM 40171V100 46,274 455,322 SH   DFND 1, 2 455,322 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 79,538 1,021,308 SH   DFND 1, 2 961,161 0 60,147
HAEMONETICS CORP MASS COM 405024100 142,936 1,287,600 SH   DFND 1, 2 1,287,600 0 0
HALLIBURTON CO COM 406216101 1,301,979 60,670,049 SH   DFND 1, 2 60,670,049 0 0
HAWAIIAN ELEC INDUSTRIES COM 419870100 9,813 220,859 SH   DFND 1, 2 220,859 0 0
HEICO CORP NEW COM 422806109 382,252 3,038,571 SH   DFND 1, 2 3,038,571 0 0
HELMERICH & PAYNE INC COM 423452101 36,666 1,360,000 SH   DFND 1, 2 1,360,000 0 0
HENRY JACK & ASSOC INC COM 426281101 216,912 1,429,683 SH   DFND 1, 2 1,429,678 0 5
HESS CORP COM 42809H107 248,183 3,507,386 SH   DFND 1, 2 3,507,386 0 0
HILTON WORLDWIDE HLDGS INC COM 43300A203 92,352 763,745 SH   DFND 1, 2 763,745 0 0
HOME DEPOT INC COM 437076102 11,914,237 39,031,134 SH   DFND 1, 2 38,991,955 0 39,179
HONEYWELL INTL INC COM 438516106 6,170,467 28,425,992 SH   DFND 1, 2 28,390,173 0 35,819
HUBBELL INC COM 443510607 342,943 1,835,000 SH   DFND 1, 2 1,835,000 0 0
HUBSPOT INC COM 443573100 952,927 2,097,988 SH   DFND 1, 2 2,097,984 0 4
HUMANA INC COM 444859102 1,835,310 4,377,520 SH   DFND 1, 2 4,372,090 0 5,430
HUNTSMAN CORP COM 447011107 536,638 18,613,868 SH   DFND 1, 2 18,613,868 0 0
HUYA INC ADS REP SHS A 44852D108 88,900 4,563,665 SH   DFND 1, 2 4,563,665 0 0
ICICI BANK LIMITED ADR 45104G104 1,741 107,555 SH   DFND 1, 2 43 0 107,512
IDEX CORP COM 45167R104 376,864 1,800,373 SH   DFND 1, 2 1,791,384 0 8,989
IDEXX LABS INC COM 45168D104 476,541 974,000 SH   DFND 1, 2 970,509 0 3,491
IHEARTMEDIA INC COM CL A 45174J509 7,283 401,284 SH   DFND 1, 2 401,284 0 0
ILLINOIS TOOL WKS INC COM 452308109 340,809 1,538,500 SH   DFND 1, 2 1,538,500 0 0
ILLUMINA INC COM 452327109 581,995 1,515,375 SH   DFND 1, 2 1,515,375 0 0
INCYTE CORP COM 45337C102 32,183 396,000 SH   DFND 1, 2 396,000 0 0
INHIBRX INC COM 45720L107 24,084 1,200,000 SH   DFND 1, 2 1,200,000 0 0
INPHI CORP COM 45772F107 46,030 258,000 SH   DFND 1, 2 258,000 0 0
INSULET CORP COM 45784P101 1,811,202 6,941,587 SH   DFND 1, 2 6,935,842 0 5,745
INTEL CORP COM 458140100 1,078,185 16,846,834 SH   DFND 1, 2 16,794,749 0 52,085
INTERCONTINENTAL HOTELS GROU SPONSORED ADS 45857P806 1,177 17,058 SH   DFND 1, 2 9 0 17,049
INTERFACE INC COM 458665304 32,687 2,619,158 SH   DFND 1, 2 2,619,158 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 2,155,972 19,304,963 SH   DFND 1, 2 19,290,429 0 14,534
INTUITIVE SURGICAL INC COM NEW 46120E602 2,806,304 3,797,835 SH   DFND 1, 2 3,792,367 0 5,468
IRIDIUM COMMUNICATIONS INC COM 46269C102 64,510 1,563,868 SH   DFND 1, 2 1,563,868 0 0
IRON MTN INC NEW COM 46284V101 1,209,254 32,673,706 SH   DFND 1, 2 32,673,706 0 0
ISHARES TR CORE S&P500 ETF 464287200 3,756 9,478 SH   DFND 1, 2 41 0 9,437
ISHARES TR MSCI ACWI ETF 464288257 718 7,564 SH   DFND 1, 2 0 0 7,564
JOYY INC ADS REPSTG COM A 46591M109 249,845 2,665,587 SH   DFND 1, 2 2,665,587 0 0
JPMORGAN CHASE & CO COM 46625H100 12,093,978 79,444,252 SH   DFND 1, 2 79,364,793 0 79,459
JACOBS ENGR GROUP INC COM 469814107 825,992 6,389,663 SH   DFND 1, 2 6,389,663 0 0
JAMF HLDG CORP COM 47074L105 75,246 2,130,403 SH   DFND 1, 2 2,130,403 0 0
JD.COM INC SPON ADR CL A 47215P106 1,255 15,115 SH   DFND 1, 2 6 0 15,109
JELD-WEN HLDG INC COM 47580P103 11,491 415,000 SH   DFND 1, 2 415,000 0 0
JOHN BEAN TECHNOLOGIES CORP COM 477839104 48,944 367,061 SH   DFND 1, 2 367,061 0 0
JOHNSON & JOHNSON COM 478160104 1,958,887 11,918,888 SH   DFND 1, 2 11,891,616 0 27,272
KE HLDGS INC SPONSORED ADS 482497104 364,789 6,402,056 SH   DFND 1, 2 6,385,176 0 16,880
KKR & CO INC COM 48251W104 291,469 5,966,611 SH   DFND 1, 2 5,966,611 0 0
KB HOME COM 48666K109 137,632 2,957,918 SH   DFND 1, 2 2,957,918 0 0
KELLOGG CO COM 487836108 953,253 15,059,286 SH   DFND 1, 2 15,059,286 0 0
KEURIG DR PEPPER INC COM 49271V100 1,596,490 46,450,108 SH   DFND 1, 2 46,450,108 0 0
KEYCORP COM 493267108 284,116 14,220,000 SH   DFND 1, 2 14,220,000 0 0
KEYSIGHT TECHNOLOGIES INC COM 49338L103 146,193 1,019,475 SH   DFND 1, 2 1,019,475 0 0
KIMBERLY-CLARK CORP COM 494368103 185,162 1,331,622 SH   DFND 1, 2 1,331,622 0 0
KINGSOFT CLOUD HLDGS LTD ADS 49639K101 22,077 561,476 SH   DFND 1, 2 561,476 0 0
KINSALE CAP GROUP INC COM 49714P108 14,341 87,020 SH   DFND 1, 2 87,020 0 0
KONINKLIJKE PHILIPS N V NY REG SH NEW 500472303 1,715 30,227 SH   DFND 1, 2 12 0 30,215
KONTOOR BRANDS INC COM 50050N103 262,921 5,417,692 SH   DFND 1, 2 5,417,692 0 0
KRAFT HEINZ CO COM 500754106 383,372 9,584,295 SH   DFND 1, 2 9,584,295 0 0
KROGER CO COM 501044101 369,907 10,278,061 SH   DFND 1, 2 10,278,061 0 0
KRONOS BIO INC COM 50107A104 58,146 1,986,540 SH   DFND 1, 2 1,986,540 0 0
L3HARRIS TECHNOLOGIES INC COM 502431109 836,826 4,128,803 SH   DFND 1, 2 4,128,803 0 0
LAM RESEARCH CORP COM 512807108 219,489 368,740 SH   DFND 1, 2 368,740 0 0
LAMAR ADVERTISING CO NEW CL A 512816109 188,152 2,003,322 SH   DFND 1, 2 2,003,322 0 0
LAS VEGAS SANDS CORP COM 517834107 180,761 2,975,000 SH   DFND 1, 2 2,975,000 0 0
LAUDER ESTEE COS INC CL A 518439104 45,794 157,448 SH   DFND 1, 2 157,448 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 34,635 1,193,479 SH   DFND 1, 2 1,193,479 0 0
LEMONADE INC COM 52567D107 4,657 50,000 SH   DFND 1, 2 50,000 0 0
LENNAR CORP CL A 526057104 372,207 3,676,840 SH   DFND 1, 2 3,676,840 0 0
LENNAR CORP CL B 526057302 1,743 21,169 SH   DFND 1, 2 21,169 0 0
LENNOX INTL INC COM 526107107 474,344 1,522,334 SH   DFND 1, 2 1,522,329 0 5
LEVI STRAUSS & CO NEW CL A COM STK 52736R102 14,941 624,899 SH   DFND 1, 2 624,899 0 0
LIGHTSPEED POS INC SUB VTG SHS 53227R106 16,275 259,122 SH   DFND 1, 2 259,122 0 0
LILLY ELI & CO COM 532457108 2,728,352 14,604,177 SH   DFND 1, 2 14,604,177 0 0
LIVE NATION ENTERTAINMENT IN COM 538034109 174,344 2,059,582 SH   DFND 1, 2 2,059,582 0 0
LIVE NATION ENTERTAINMENT IN NOTE 2.000% 2/1 538034AU3 5,485 4,930,000 PRN   DFND 1, 2 4,930,000 0 0
LOCKHEED MARTIN CORP COM 539830109 5,170,515 13,993,232 SH   DFND 1, 2 13,978,537 0 14,695
LORDSTOWN MOTORS CORP COM CL A 54405Q100 17,596 1,495,000 SH   DFND 1, 2 1,495,000 0 0
LUFAX HOLDING LTD ADS REP SHS CL A 54975P102 413,966 28,510,084 SH   DFND 1, 2 28,510,084 0 0
LULULEMON ATHLETICA INC COM 550021109 50,530 164,747 SH   DFND 1, 2 164,747 0 0
M D C HLDGS INC COM 552676108 62,069 1,044,930 SH   DFND 1, 2 1,044,930 0 0
MGM GROWTH PPTYS LLC CL A COM 55303A105 365,018 11,190,000 SH   DFND 1, 2 11,190,000 0 0
MSCI INC COM 55354G100 8,281 19,751 SH   DFND 1, 2 19,747 0 4
MACYS INC COM 55616P104 30,761 1,900,000 SH   DFND 1, 2 1,900,000 0 0
MAGNA INTL INC COM 559222401 1,004 11,400 SH   DFND 1, 2 11,400 0 0
MANPOWERGROUP INC COM 56418H100 474,524 4,798,016 SH   DFND 1, 2 4,798,016 0 0
MANULIFE FINL CORP COM 56501R106 432,794 20,121,785 SH   DFND 1, 2 20,121,785 0 0
MARKETAXESS HLDGS INC COM 57060D108 75,385 151,400 SH   DFND 1, 2 151,400 0 0
MARSH & MCLENNAN COS INC COM 571748102 2,000,355 16,423,373 SH   DFND 1, 2 16,380,279 0 43,094
MARRIOTT INTL INC NEW CL A 571903202 820,013 5,536,513 SH   DFND 1, 2 5,536,513 0 0
MASCO CORP COM 574599106 97,338 1,625,000 SH   DFND 1, 2 1,625,000 0 0
MASTERCARD INCORPORATED CL A 57636Q104 3,394,045 9,532,420 SH   DFND 1, 2 9,519,793 0 12,627
MATCH GROUP INC NEW COM 57667L107 255,414 1,859,180 SH   DFND 1, 2 1,859,173 0 7
MCDONALDS CORP COM 580135101 268,875 1,199,583 SH   DFND 1, 2 1,199,583 0 0
MELCO RESORTS AND ENTMNT LTD ADR 585464100 382,638 19,218,196 SH   DFND 1, 2 19,188,428 0 29,768
MERCADOLIBRE INC COM 58733R102 3,406,948 2,314,423 SH   DFND 1, 2 2,309,736 0 4,687
MERCK & CO. INC COM 58933Y105 973,576 12,629,151 SH   DFND 1, 2 12,586,871 0 42,280
METTLER TOLEDO INTERNATIONAL COM 592688105 110,786 95,861 SH   DFND 1, 2 95,861 0 0
MICROSOFT CORP COM 594918104 26,441,414 112,150,578 SH   DFND 1, 2 112,067,264 0 83,314
MICROSTRATEGY INC CL A NEW 594972408 25,082 36,950 SH   DFND 1, 2 36,950 0 0
MICRON TECHNOLOGY INC COM 595112103 129,091 1,463,446 SH   DFND 1, 2 1,463,420 0 26
MID-AMER APT CMNTYS INC COM 59522J103 443,956 3,075,339 SH   DFND 1, 2 3,075,339 0 0
MIDDLEBY CORP COM 596278101 116,357 702,000 SH   DFND 1, 2 702,000 0 0
MODERNA INC COM 60770K107 237,868 1,816,482 SH   DFND 1, 2 1,816,482 0 0
MOELIS & CO CL A 60786M105 39,459 719,000 SH   DFND 1, 2 719,000 0 0
MOLINA HEALTHCARE INC COM 60855R100 1,280,606 5,478,295 SH   DFND 1, 2 5,478,295 0 0
MONDELEZ INTL INC CL A 609207105 2,120,299 36,225,848 SH   DFND 1, 2 36,225,848 0 0
MONEYGRAM INTL INC COM NEW 60935Y208 10,662 1,622,886 SH   DFND 1, 2 1,622,886 0 0
MONGODB INC CL A 60937P106 1,994,957 7,459,737 SH   DFND 1, 2 7,459,737 0 0
MONSTER BEVERAGE CORP NEW COM 61174X109 243,405 2,672,141 SH   DFND 1, 2 2,672,141 0 0
MOODYS CORP COM 615369105 512,586 1,716,588 SH   DFND 1, 2 1,712,947 0 3,641
MORGAN STANLEY COM NEW 617446448 458,961 5,909,875 SH   DFND 1, 2 5,909,875 0 0
MOTOROLA SOLUTIONS INC COM NEW 620076307 1,228,674 6,533,762 SH   DFND 1, 2 6,533,762 0 0
NMI HLDGS INC CL A 629209305 17,375 735,000 SH   DFND 1, 2 735,000 0 0
NVR INC COM 62944T105 307,421 65,257 SH   DFND 1, 2 65,257 0 0
NASDAQ INC COM 631103108 1,360,349 9,225,206 SH   DFND 1, 2 9,225,206 0 0
NATERA INC COM 632307104 65,290 643,000 SH   DFND 1, 2 643,000 0 0
NAVIENT CORPORATION COM 63938C108 18,174 1,270,000 SH   DFND 1, 2 1,270,000 0 0
NETFLIX INC COM 64110L106 7,042,482 13,500,195 SH   DFND 1, 2 13,496,602 0 3,593
NEVRO CORP COM 64157F103 35,294 253,000 SH   DFND 1, 2 253,000 0 0
NEW FORTRESS ENERGY INC COM CL A 644393100 169,240 3,686,344 SH   DFND 1, 2 3,686,344 0 0
NEW YORK TIMES CO CL A 650111107 507,313 10,021,991 SH   DFND 1, 2 10,021,991 0 0
NEWMONT CORP COM 651639106 33,149 550,000 SH   DFND 1, 2 550,000 0 0
NEXSTAR MEDIA GROUP INC CL A 65336K103 157,353 1,120,508 SH   DFND 1, 2 1,120,508 0 0
NEXTERA ENERGY INC COM 65339F101 912,119 12,063,468 SH   DFND 1, 2 12,063,468 0 0
NEXTERA ENERGY INC UNIT 99/99/9999 65339F739 27,843 561,344 SH   DFND 1, 2 561,344 0 0
NEXTERA ENERGY INC UNIT 99/99/9999 65339F770 492,495 9,943,364 SH   DFND 1, 2 9,943,364 0 0
NIKE INC CL B 654106103 2,108,962 15,869,978 SH   DFND 1, 2 15,853,588 0 16,390
908 DEVICES INC COM 65443P102 5,456 112,500 SH   DFND 1, 2 112,500 0 0
NORDSTROM INC COM 655664100 28,781 760,000 SH   DFND 1, 2 760,000 0 0
NORFOLK SOUTHN CORP COM 655844108 2,111,509 7,863,472 SH   DFND 1, 2 7,858,106 0 5,366
NORTHERN OIL AND GAS INC MN COM 665531307 53,089 4,394,756 SH   DFND 1, 2 4,394,756 0 0
NORTHROP GRUMMAN CORP COM 666807102 600,180 1,854,498 SH   DFND 1, 2 1,844,233 0 10,265
NORTONLIFELOCK INC COM 668771108 1,333,982 62,746,098 SH   DFND 1, 2 62,746,098 0 0
NOVARTIS AG SPONSORED ADR 66987V109 41,290 482,288 SH   DFND 1, 2 440,868 0 41,420
NOVAVAX INC COM NEW 670002401 112,019 617,834 SH   DFND 1, 2 617,834 0 0
NOVO-NORDISK A S ADR 670100205 1,888 27,801 SH   DFND 1, 2 11 0 27,790
NU SKIN ENTERPRISES INC CL A 67018T105 47,601 900,000 SH   DFND 1, 2 900,000 0 0
NUCOR CORP COM 670346105 1,262,939 15,733,575 SH   DFND 1, 2 15,689,930 0 43,645
NUVASIVE INC COM 670704105 50,219 766,000 SH   DFND 1, 2 766,000 0 0
OAK STR HEALTH INC COM 67181A107 278,389 5,129,710 SH   DFND 1, 2 5,129,710 0 0
OASIS PETROLEUM INC COM NEW 674215207 122,618 2,064,618 SH   DFND 1, 2 2,064,618 0 0
OKTA INC CL A 679295105 110,215 500,000 SH   DFND 1, 2 500,000 0 0
OSCAR HEALTH INC CL A 687793109 67,200 2,500,000 SH   DFND 1, 2 2,500,000 0 0
OSHKOSH CORP COM 688239201 17,799 150,000 SH   DFND 1, 2 150,000 0 0
PG&E CORP UNIT 99/99/9999 69331C140 6,886 60,350 SH   DFND 1, 2 60,350 0 0
PGT INNOVATIONS INC COM 69336V101 28,608 1,133,000 SH   DFND 1, 2 1,133,000 0 0
PNC FINL SVCS GROUP INC COM 693475105 2,536,121 14,457,965 SH   DFND 1, 2 14,435,856 0 22,109
PPD INC COM 69355F102 61,759 1,632,097 SH   DFND 1, 2 1,632,071 0 26
PACCAR INC COM 693718108 1,998,342 21,506,044 SH   DFND 1, 2 21,506,044 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 112,921 3,390,000 SH   DFND 1, 2 3,390,000 0 0
PACKAGING CORP AMER COM 695156109 716,712 5,329,505 SH   DFND 1, 2 5,329,505 0 0
GREAT WESTN NATL BK PORTLAND COM 695263103 46,543 1,220,000 SH   DFND 1, 2 1,220,000 0 0
PARKER-HANNIFIN CORP COM 701094104 2,031,644 6,440,872 SH   DFND 1, 2 6,440,872 0 0
PAYCHEX INC COM 704326107 142,183 1,450,549 SH   DFND 1, 2 1,450,549 0 0
PAYCOM SOFTWARE INC COM 70432V102 355,480 960,600 SH   DFND 1, 2 960,600 0 0
PAYLOCITY HLDG CORP COM 70438V106 26,975 150,000 SH   DFND 1, 2 150,000 0 0
PAYPAL HLDGS INC COM 70450Y103 6,517,955 26,840,955 SH   DFND 1, 2 26,824,729 0 16,226
PELOTON INTERACTIVE INC CL A COM 70614W100 1,015,448 9,031,022 SH   DFND 1, 2 9,031,022 0 0
PEMBINA PIPELINE CORP COM 706327103 690 23,896 SH   DFND 1, 2 23,896 0 0
PENN NATL GAMING INC NOTE 2.750% 5/1 707569AU3 393 87,000 PRN   DFND 1, 2 87,000 0 0
PENUMBRA INC COM 70975L107 175,498 648,598 SH   DFND 1, 2 648,598 0 0
PEPSICO INC COM 713448108 161,254 1,140,005 SH   DFND 1, 2 1,140,000 0 5
PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408 32,249 3,802,957 SH   DFND 1, 2 3,802,957 0 0
PFIZER INC COM 717081103 8,336,004 230,086,394 SH   DFND 1, 2 229,871,280 0 215,114
PHILIP MORRIS INTL INC COM 718172109 7,072,315 79,697,032 SH   DFND 1, 2 79,697,032 0 0
PIONEER NAT RES CO COM 723787107 1,380,591 8,692,685 SH   DFND 1, 2 8,682,121 0 10,564
PLAYTIKA HLDG CORP COM 72815L107 94,206 3,462,170 SH   DFND 1, 2 3,462,170 0 0
POLARIS INC COM 731068102 64,748 485,000 SH   DFND 1, 2 485,000 0 0
POOL CORP COM 73278L105 135,335 392,004 SH   DFND 1, 2 391,999 0 5
PORCH GROUP INC COM 733245104 73,877 4,173,853 SH   DFND 1, 2 4,173,853 0 0
PRECISION BIOSCIENCES INC COM 74019P108 42,042 4,062,000 SH   DFND 1, 2 4,062,000 0 0
PROCTER AND GAMBLE CO COM 742718109 1,412,052 10,426,432 SH   DFND 1, 2 10,426,432 0 0
PROGRESSIVE CORP COM 743315103 932,193 9,749,954 SH   DFND 1, 2 9,749,954 0 0
PROLOGIS INC. COM 74340W103 203,096 1,916,000 SH   DFND 1, 2 1,916,000 0 0
PUBLIC SVC ENTERPRISE GRP IN COM 744573106 483,313 8,027,123 SH   DFND 1, 2 8,027,123 0 0
PUBLIC STORAGE COM 74460D109 182,109 738,000 SH   DFND 1, 2 738,000 0 0
PULMONX CORP COM 745848101 48,484 1,060,000 SH   DFND 1, 2 1,060,000 0 0
QUALCOMM INC COM 747525103 254,838 1,922,000 SH   DFND 1, 2 1,922,000 0 0
QUALTRICS INTL INC COM CL A 747601201 55,173 1,676,492 SH   DFND 1, 2 1,676,492 0 0
RADIAN GROUP INC COM 750236101 49,569 2,132,000 SH   DFND 1, 2 2,132,000 0 0
RATTLER MIDSTREAM LP COM UNITS 75419T103 30,399 2,859,750 SH   DFND 1, 2 2,859,750 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 405,217 5,244,169 SH   DFND 1, 2 5,244,169 0 0
RED ROCK RESORTS INC CL A 75700L108 102,412 3,142,436 SH   DFND 1, 2 3,142,436 0 0
REDWOOD TR INC COM 758075402 26,670 2,562,000 SH   DFND 1, 2 2,562,000 0 0
REGENCY CTRS CORP COM 758849103 283,146 4,992,876 SH   DFND 1, 2 4,992,876 0 0
REGENERON PHARMACEUTICALS COM 75886F107 2,925,946 6,184,120 SH   DFND 1, 2 6,180,538 0 3,582
REGIONS FINANCIAL CORP NEW COM 7591EP100 474,319 22,958,336 SH   DFND 1, 2 22,958,336 0 0
REPAY HLDGS CORP COM CL A 76029L100 65,486 2,789,000 SH   DFND 1, 2 2,789,000 0 0
REPUBLIC SVCS INC COM 760759100 219,402 2,208,371 SH   DFND 1, 2 2,208,371 0 0
RESMED INC COM 761152107 712,684 3,673,252 SH   DFND 1, 2 3,673,252 0 0
RESTAURANT BRANDS INTL INC COM 76131D103 2,295,295 35,309,862 SH   DFND 1, 2 35,286,167 0 23,695
REVANCE THERAPEUTICS INC COM 761330109 71,862 2,571,102 SH   DFND 1, 2 2,571,102 0 0
REVOLUTION MEDICINES INC COM 76155X100 56,341 1,228,000 SH   DFND 1, 2 1,228,000 0 0
REXNORD CORP COM 76169B102 276,953 5,881,355 SH   DFND 1, 2 5,881,355 0 0
RINGCENTRAL INC CL A 76680R206 3,287,889 11,037,630 SH   DFND 1, 2 11,037,630 0 0
RIO TINTO PLC SPONSORED ADR 767204100 189,004 2,433,966 SH   DFND 1, 2 2,407,123 0 26,843
ROYAL BK CDA COM 780087102 235 2,549 SH   DFND 1, 2 2,547 0 2
ROYAL DUTCH SHELL PLC SPON ADR B 780259107 6,102 165,680 SH   DFND 1, 2 165,680 0 0
ROYAL GOLD INC COM 780287108 826,528 7,680,060 SH   DFND 1, 2 7,680,060 0 0
RUBIUS THERAPEUTICS INC COM 78116T103 38,434 1,450,333 SH   DFND 1, 2 1,450,333 0 0
RYANAIR HOLDINGS PLC SPONSORED ADS 783513203 450 3,910 SH   DFND 1, 2 3,910 0 0
S&P GLOBAL INC COM 78409V104 1,516,171 4,296,683 SH   DFND 1, 2 4,296,683 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 1,633 4,138 SH   DFND 1, 2 0 0 4,138
SVB FINANCIAL GROUP COM 78486Q101 467,938 947,895 SH   DFND 1, 2 947,895 0 0
SAIA INC COM 78709Y105 173,535 752,600 SH   DFND 1, 2 752,600 0 0
SAILPOINT TECHNOLOGIES HLDGS COM 78781P105 86,261 1,703,408 SH   DFND 1, 2 1,703,408 0 0
SAP SE SPON ADR 803054204 1,850 15,224 SH   DFND 1, 2 6 0 15,218
SCHOLAR ROCK HLDG CORP COM 80706P103 24,064 475,000 SH   DFND 1, 2 475,000 0 0
SCOTTS MIRACLE-GRO CO CL A 810186106 27,138 110,780 SH   DFND 1, 2 110,772 0 8
SEA LTD SPONSORD ADS 81141R100 4,442,379 19,901,521 SH   DFND 1, 2 19,874,801 0 26,720
SEACOAST BKG CORP FLA COM NEW 811707801 137,056 3,781,901 SH   DFND 1, 2 3,781,901 0 0
SEER INC COM CL A 81578P106 59,269 1,184,899 SH   DFND 1, 2 1,184,899 0 0
SERVICENOW INC COM 81762P102 111,663 223,322 SH   DFND 1, 2 221,558 0 1,764
SHAW COMMUNICATIONS INC CL B CONV 82028K200 817 31,404 SH   DFND 1, 2 31,404 0 0
SHERWIN WILLIAMS CO COM 824348106 1,214,446 1,645,545 SH   DFND 1, 2 1,643,451 0 2,094
SHOCKWAVE MED INC COM 82489T104 76,202 585,000 SH   DFND 1, 2 585,000 0 0
SHOALS TECHNOLOGIES GROUP IN CL A 82489W107 148,778 4,277,684 SH   DFND 1, 2 4,277,684 0 0
SHOPIFY INC CL A 82509L107 5,871,296 5,306,681 SH   DFND 1, 2 5,299,541 0 7,140
SILK RD MED INC COM 82710M100 140,807 2,780,000 SH   DFND 1, 2 2,780,000 0 0
SIMON PPTY GROUP INC NEW COM 828806109 213,404 1,875,749 SH   DFND 1, 2 1,875,733 0 16
SIMPLY GOOD FOODS CO COM 82900L102 150,609 4,951,000 SH   DFND 1, 2 4,951,000 0 0
SITIME CORP COM 82982T106 9,638 97,750 SH   DFND 1, 2 97,750 0 0
SIX FLAGS ENTMT CORP NEW COM 83001A102 70,356 1,514,000 SH   DFND 1, 2 1,514,000 0 0
SMARTSHEET INC COM CL A 83200N103 897,405 14,040,307 SH   DFND 1, 2 14,024,761 0 15,546
SNAP INC CL A 83304A106 1,746,099 33,392,603 SH   DFND 1, 2 33,392,603 0 0
SNOWFLAKE INC CL A 833445109 85,026 370,837 SH   DFND 1, 2 370,837 0 0
SOUTH ST CORP COM 840441109 36,960 470,765 SH   DFND 1, 2 470,765 0 0
SOUTHWEST AIRLS CO COM 844741108 202,408 3,314,896 SH   DFND 1, 2 3,314,896 0 0
SOUTHWEST AIRLS CO NOTE 1.250% 5/0 844741BG2 7,263 4,218,000 PRN   DFND 1, 2 4,218,000 0 0
SOUTHWESTERN ENERGY CO COM 845467109 1,067 229,524 SH   DFND 1, 2 229,524 0 0
SQUARE INC CL A 852234103 1,055,381 4,648,230 SH   DFND 1, 2 4,648,230 0 0
STARBUCKS CORP COM 855244109 94,849 868,022 SH   DFND 1, 2 868,022 0 0
STERICYCLE INC COM 858912108 29,031 430,024 SH   DFND 1, 2 430,000 0 24
STEPSTONE GROUP INC COM CL A 85914M107 52,799 1,497,000 SH   DFND 1, 2 1,497,000 0 0
STMICROELECTRONICS N V NY REGISTRY 861012102 1,433 38,268 SH   DFND 1, 2 17 0 38,251
STRATEGIC ED INC COM 86272C103 122,398 1,331,711 SH   DFND 1, 2 1,331,711 0 0
SUN CMNTYS INC COM 866674104 733,015 4,885,466 SH   DFND 1, 2 4,885,466 0 0
SUN CTRY AIRLS HLDGS INC COM 866683105 23,996 700,000 SH   DFND 1, 2 700,000 0 0
SUN LIFE FINANCIAL INC. COM 866796105 818 16,189 SH   DFND 1, 2 16,189 0 0
SUNCOR ENERGY INC NEW COM 867224107 198,879 9,513,921 SH   DFND 1, 2 9,513,921 0 0
SYNCHRONY FINANCIAL COM 87165B103 2,062,913 50,735,675 SH   DFND 1, 2 50,735,641 0 34
SYNEOS HEALTH INC CL A 87166B102 53,088 699,902 SH   DFND 1, 2 699,902 0 0
T-MOBILE US INC COM 872590104 1,277,098 10,193,134 SH   DFND 1, 2 10,193,134 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 4,290,230 36,275,390 SH   DFND 1, 2 36,143,694 0 131,696
TANDEM DIABETES CARE INC COM NEW 875372203 272,541 3,088,279 SH   DFND 1, 2 3,088,279 0 0
TARGET CORP COM 87612E106 1,567,235 7,912,531 SH   DFND 1, 2 7,912,531 0 0
TC ENERGY CORP COM 87807B107 937,784 20,459,754 SH   DFND 1, 2 20,416,895 0 42,859
TELADOC HEALTH INC COM 87918A105 1,036,364 5,702,142 SH   DFND 1, 2 5,702,142 0 0
TELUS CORPORATION COM 87971M103 70,162 3,522,670 SH   DFND 1, 2 3,522,670 0 0
TERMINIX GLOBAL HOLDINGS INC COM 88087E100 21,704 455,300 SH   DFND 1, 2 455,300 0 0
TESLA INC COM 88160R101 27,334,674 40,925,678 SH   DFND 1, 2 40,900,491 0 25,187
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 611,844 53,020,773 SH   DFND 1, 2 52,945,202 0 75,571
TEXAS INSTRS INC COM 882508104 1,508,559 7,982,217 SH   DFND 1, 2 7,982,204 0 13
TEXTRON INC COM 883203101 43,742 780,000 SH   DFND 1, 2 780,000 0 0
TG THERAPEUTICS INC COM 88322Q108 152,020 3,153,943 SH   DFND 1, 2 3,153,943 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 7,639,398 16,739,194 SH   DFND 1, 2 16,731,904 0 7,290
TOLL BROTHERS INC COM 889478103 765,212 13,488,670 SH   DFND 1, 2 13,488,670 0 0
TOPBUILD CORP COM 89055F103 287,156 1,371,129 SH   DFND 1, 2 1,371,129 0 0
TORONTO DOMINION BK ONT COM NEW 891160509 2,401,416 36,822,230 SH   DFND 1, 2 36,781,454 0 40,776
TRADEWEB MKTS INC CL A 892672106 315,288 4,260,643 SH   DFND 1, 2 4,260,643 0 0
TRANSDIGM GROUP INC COM 893641100 499,356 849,360 SH   DFND 1, 2 849,360 0 0
TRUPANION INC COM 898202106 117,280 1,538,900 SH   DFND 1, 2 1,538,900 0 0
TRUIST FINL CORP COM 89832Q109 74,800 1,282,573 SH   DFND 1, 2 1,282,573 0 0
TURQUOISE HILL RES LTD COM 900435207 23,135 1,437,830 SH   DFND 1, 2 1,437,830 0 0
TWIST BIOSCIENCE CORP COM 90184D100 414,079 3,343,124 SH   DFND 1, 2 3,343,124 0 0
TWITTER INC COM 90184L102 389,992 6,129,056 SH   DFND 1, 2 6,129,056 0 0
TWITTER INC NOTE 0.250% 6/1 90184LAF9 1,797 1,350,000 PRN   DFND 1, 2 1,350,000 0 0
TYLER TECHNOLOGIES INC COM 902252105 438,748 1,033,492 SH   DFND 1, 2 1,033,492 0 0
UBER TECHNOLOGIES INC COM 90353T100 1,337,861 24,543,405 SH   DFND 1, 2 24,543,405 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 315,040 2,766,905 SH   DFND 1, 2 2,766,905 0 0
UMPQUA HLDGS CORP COM 904214103 31,336 1,785,500 SH   DFND 1, 2 1,785,500 0 0
UNILEVER PLC SPON ADR NEW 904767704 45,021 806,390 SH   DFND 1, 2 806,390 0 0
UNION PAC CORP COM 907818108 1,577,537 7,157,266 SH   DFND 1, 2 7,151,907 0 5,359
UNITED AIRLS HLDGS INC COM 910047109 227,922 3,961,111 SH   DFND 1, 2 3,961,111 0 0
UNITED PARCEL SERVICE INC CL B 911312106 577,053 3,394,629 SH   DFND 1, 2 3,394,629 0 0
UNITED RENTALS INC COM 911363109 255,025 774,421 SH   DFND 1, 2 774,417 0 4
UNITEDHEALTH GROUP INC COM 91324P102 12,656,979 34,017,627 SH   DFND 1, 2 33,990,795 0 26,832
UPSTART HLDGS INC COM 91680M107 25,772 200,000 SH   DFND 1, 2 200,000 0 0
V F CORP COM 918204108 689,592 8,628,460 SH   DFND 1, 2 8,602,112 0 26,348
VAIL RESORTS INC COM 91879Q109 20,708 71,000 SH   DFND 1, 2 71,000 0 0
VALE S A SPONSORED ADS 91912E105 2,109,846 121,399,165 SH   DFND 1, 2 121,200,873 0 198,292
VALERO ENERGY CORP COM 91913Y100 1,357,124 18,954,244 SH   DFND 1, 2 18,954,244 0 0
VALLEY NATL BANCORP COM 919794107 62,751 4,567,000 SH   DFND 1, 2 4,567,000 0 0
VANGUARD INTL EQUITY INDEX F TT WRLD ST ETF 922042742 1,036 10,674 SH   DFND 1, 2 0 0 10,674
VANGUARD INTL EQUITY INDEX F ALLWRLD EX US 922042775 486 8,004 SH   DFND 1, 2 0 0 8,004
VERIZON COMMUNICATIONS INC COM 92343V104 2,938,160 50,526,818 SH   DFND 1, 2 50,470,091 0 56,727
VERTEX PHARMACEUTICALS INC COM 92532F100 2,075,288 9,657,475 SH   DFND 1, 2 9,653,898 0 3,577
VIAVI SOLUTIONS INC COM 925550105 91,562 5,832,000 SH   DFND 1, 2 5,832,000 0 0
VIACOMCBS INC CL B 92556H206 128,783 2,855,498 SH   DFND 1, 2 2,855,498 0 0
VIATRIS INC COM 92556V106 240,805 17,237,283 SH   DFND 1, 2 17,237,278 0 5
VICI PPTYS INC COM 925652109 259,007 9,171,644 SH   DFND 1, 2 9,171,644 0 0
VICTORY CAP HLDGS INC COM CL A 92645B103 20,755 812,000 SH   DFND 1, 2 812,000 0 0
VINE ENERGY INC CL A 92735P103 18,893 1,375,000 SH   DFND 1, 2 1,375,000 0 0
VIPER ENERGY PARTNERS LP COM UNT RP INT 92763M105 21,185 1,455,000 SH   DFND 1, 2 1,455,000 0 0
VISA INC COM CL A 92826C839 2,103,441 9,934,527 SH   DFND 1, 2 9,914,572 0 19,955
VISTRA CORP COM 92840M102 6,590 372,765 SH   DFND 1, 2 372,765 0 0
VULCAN MATLS CO COM 929160109 1,100,354 6,520,615 SH   DFND 1, 2 6,520,615 0 0
VROOM INC COM 92918V109 21,016 539,000 SH   DFND 1, 2 539,000 0 0
WADDELL & REED FINL INC CL A 930059100 46,343 1,850,000 SH   DFND 1, 2 1,850,000 0 0
WALMART INC COM 931142103 322,539 2,374,578 SH   DFND 1, 2 2,374,578 0 0
WALGREENS BOOTS ALLIANCE INC COM 931427108 1,174,159 21,387,237 SH   DFND 1, 2 21,387,237 0 0
WARNER MUSIC GROUP CORP COM CL A 934550203 54,836 1,597,307 SH   DFND 1, 2 1,597,307 0 0
WASTE CONNECTIONS INC COM 94106B101 190,158 1,761,048 SH   DFND 1, 2 1,761,048 0 0
WASTE MGMT INC DEL COM 94106L109 206,041 1,596,968 SH   DFND 1, 2 1,596,968 0 0
WATSCO INC COM 942622200 269,770 1,034,591 SH   DFND 1, 2 1,034,591 0 0
WAYFAIR INC CL A 94419L101 227,644 723,253 SH   DFND 1, 2 723,253 0 0
WESTLAKE CHEM CORP COM 960413102 231,772 2,610,337 SH   DFND 1, 2 2,610,337 0 0
WHEATON PRECIOUS METALS CORP COM 962879102 701,134 18,349,495 SH   DFND 1, 2 18,349,495 0 0
WILLSCOT MOBIL MINI HLDNG CO COM CL A 971378104 117,799 4,245,000 SH   DFND 1, 2 4,245,000 0 0
WORKDAY INC CL A 98138H101 99,286 399,652 SH   DFND 1, 2 399,652 0 0
WYNN RESORTS LTD COM 983134107 110,235 879,281 SH   DFND 1, 2 879,281 0 0
XCEL ENERGY INC COM 98389B100 898,181 13,504,769 SH   DFND 1, 2 13,462,056 0 42,713
XENON PHARMACEUTICALS INC COM 98420N105 17,247 963,500 SH   DFND 1, 2 963,500 0 0
XPENG INC ADS 98422D105 365,886 10,021,517 SH   DFND 1, 2 10,021,517 0 0
YETI HLDGS INC COM 98585X104 122,829 1,701,000 SH   DFND 1, 2 1,701,000 0 0
YUM BRANDS INC COM 988498101 339,558 3,138,825 SH   DFND 1, 2 3,138,825 0 0
ZAI LAB LTD ADR 98887Q104 1,117,943 8,378,726 SH   DFND 1, 2 8,371,174 0 7,552
ZENDESK INC COM 98936J101 693,698 5,230,718 SH   DFND 1, 2 5,230,718 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 16,054 370,000 SH   DFND 1, 2 370,000 0 0
ZILLOW GROUP INC CL A 98954M101 171,235 1,303,357 SH   DFND 1, 2 1,303,357 0 0
ZILLOW GROUP INC CL C CAP STK 98954M200 414,995 3,201,132 SH   DFND 1, 2 3,201,132 0 0
ZOETIS INC CL A 98978V103 1,440,817 9,149,242 SH   DFND 1, 2 9,136,403 0 12,839
ZOOMINFO TECHNOLOGIES INC COM CL A 98980F104 311,415 6,368,402 SH   DFND 1, 2 6,368,402 0 0
EURONAV NV SHS B38564108 6,863 750,000 SH   DFND 1, 2 750,000 0 0
AON PLC SHS CL A G0403H108 444,868 1,933,284 SH   DFND 1, 2 1,933,284 0 0
ARCH CAP GROUP LTD ORD G0450A105 727,189 18,952,022 SH   DFND 1, 2 18,952,022 0 0
ARCO PLATFORM LTD COM CL A G04553106 43,141 1,702,501 SH   DFND 1, 2 1,702,501 0 0
ATLASSIAN CORP PLC CL A G06242104 4,047 19,200 SH   DFND 1, 2 19,200 0 0
BANK OF NT BUTTERFIELD&SON L SHS NEW G0772R208 74,529 1,950,000 SH   DFND 1, 2 1,950,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 323,975 4,739,936 SH   DFND 1, 2 4,739,936 0 0
BROOKFIELD PROPERTY PARTRS L UNIT LTD PARTN G16249107 51,082 2,871,366 SH   DFND 1, 2 2,871,366 0 0
BROOKFIELD INFRAST PARTNERS LP INT UNIT G16252101 1,016,161 19,034,269 SH   DFND 1, 2 19,034,269 0 0
BUNGE LIMITED COM G16962105 579,164 7,306,213 SH   DFND 1, 2 7,306,213 0 0
COCA COLA EUROPEAN PARTNERS SHS G25839104 186,685 3,579,084 SH   DFND 1, 2 3,579,084 0 0
ENSTAR GROUP LIMITED SHS G3075P101 146,681 594,500 SH   DFND 1, 2 594,500 0 0
ESSENT GROUP LTD COM G3198U102 188,573 3,970,800 SH   DFND 1, 2 3,970,800 0 0
FRESH DEL MONTE PRODUCE INC ORD G36738105 29,432 1,028,000 SH   DFND 1, 2 1,028,000 0 0
HELEN OF TROY LTD COM G4388N106 93,849 445,500 SH   DFND 1, 2 445,500 0 0
JANUS HENDERSON GROUP PLC ORD SHS G4474Y214 37,381 1,200,041 SH   DFND 1, 2 1,200,041 0 0
JOHNSON CTLS INTL PLC SHS G51502105 279,582 4,685,478 SH   DFND 1, 2 4,685,452 0 26
LINDE PLC SHS G5494J103 1,956,660 6,984,850 SH   DFND 1, 2 6,960,397 0 24,453
MEDTRONIC PLC SHS G5960L103 142,535 1,206,591 SH   DFND 1, 2 1,206,591 0 0
NOMAD FOODS LTD USD ORD SHS G6564A105 13,730 500,000 SH   DFND 1, 2 500,000 0 0
NORWEGIAN CRUISE LINE HLDG L SHS G66721104 30,349 1,100,000 SH   DFND 1, 2 1,100,000 0 0
NOVOCURE LTD ORD SHS G6674U108 1,141,708 8,637,523 SH   DFND 1, 2 8,637,523 0 0
PAGSEGURO DIGITAL LTD COM CL A G68707101 861,756 18,612,736 SH   DFND 1, 2 18,593,348 0 19,388
RENAISSANCERE HLDGS LTD COM G7496G103 387,370 2,417,284 SH   DFND 1, 2 2,417,284 0 0
TRONOX HOLDINGS PLC SHS G9087Q102 37,844 2,068,000 SH   DFND 1, 2 2,068,000 0 0
VENATOR MATLS PLC SHS G9329Z100 39,535 8,538,871 SH   DFND 1, 2 8,538,871 0 0
WILLIS TOWERS WATSON PLC LTD SHS G96629103 452,148 1,975,479 SH   DFND 1, 2 1,975,479 0 0
CHUBB LIMITED COM H1467J104 1,857,542 11,758,024 SH   DFND 1, 2 11,722,276 0 35,748
LOGITECH INTL S A SHS H50430232 516,735 4,929,927 SH   DFND 1, 2 4,929,927 0 0
TE CONNECTIVITY LTD REG SHS H84989104 1,999,796 15,489,087 SH   DFND 1, 2 15,489,087 0 0
ARRIVAL GROUP SHS L0423Q108 169,334 11,708,452 SH   DFND 1, 2 11,708,452 0 0
GLOBANT S A COM L44385109 95,456 459,786 SH   DFND 1, 2 459,786 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 315 1,176 SH   DFND 1, 2 1,176 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210 4,599,433 7,451,108 SH   DFND 1, 2 7,414,851 0 36,257
FERRARI N V COM N3167Y103 26,393 126,051 SH   DFND 1, 2 126,000 0 51
LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 3,015,212 28,978,181 SH   DFND 1, 2 28,945,452 0 32,729
QIAGEN NV SHS NEW N72482123 299,831 6,157,966 SH   DFND 1, 2 6,157,966 0 0
STELLANTIS N.V SHS N82405106 1,477,370 83,463,312 SH   DFND 1, 2 83,463,312 0 0
YANDEX N V SHS CLASS A N97284108 619,917 9,677,132 SH   DFND 1, 2 9,677,132 0 0
COPA HOLDINGS SA CL A P31076105 151,129 1,870,642 SH   DFND 1, 2 1,870,642 0 0
SCORPIO TANKERS INC SHS Y7542C130 6,369 345,000 SH   DFND 1, 2 345,000 0 0