The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Axcella Health Inc | COM | 05454B105 | 41,008 | 7,901,362 | SH | DFND | 2,3 | 0 | 7,901,362 | 0 | |
| Axcella Health Inc | COM | 05454B105 | 14,978 | 2,886,023 | SH | DFND | 3,4 | 0 | 2,886,023 | 0 | |
| Axcella Health Inc | COM | 05454B105 | 9,140 | 1,761,029 | SH | DFND | 3 | 0 | 1,761,029 | 0 | |
| Codiak Biosciences Inc | COM | 192010106 | 68,520 | 2,121,354 | SH | DFND | 1,3 | 0 | 2,121,354 | 0 | |
| Codiak Biosciences Inc | COM | 192010106 | 15,696 | 485,949 | SH | DFND | 3 | 0 | 485,949 | 0 | |
| Denali Therapeutics Inc | COM | 24823R105 | 228,687 | 2,730,263 | SH | DFND | 1,3 | 0 | 2,730,263 | 0 | |
| Evelo Biosciences Inc | COM | 299734103 | 123,382 | 10,205,282 | SH | DFND | 1,3 | 0 | 10,205,282 | 0 | |
| Evelo Biosciences Inc | COM | 299734103 | 56,059 | 4,636,785 | SH | DFND | 2,3 | 0 | 4,636,785 | 0 | |
| Evelo Biosciences Inc | COM | 299734103 | 49,315 | 4,079,032 | SH | DFND | 3,4 | 0 | 4,079,032 | 0 | |
| Evelo Biosciences Inc | COM | 299734103 | 16,120 | 1,333,333 | SH | DFND | 3,6 | 0 | 1,333,333 | 0 | |
| Evelo Biosciences Inc | COM | 299734103 | 31,986 | 2,645,637 | SH | DFND | 3 | 0 | 2,645,637 | 0 | |
| Foghorn Therapeutics Inc | COM | 344174107 | 189,137 | 9,330,878 | SH | DFND | 1,3 | 0 | 9,330,878 | 0 | |
| Foghorn Therapeutics Inc | COM | 344174107 | 30,232 | 1,491,441 | SH | DFND | 3,4 | 0 | 1,491,441 | 0 | |
| Foghorn Therapeutics Inc | COM | 344174107 | 37,536 | 1,851,801 | SH | DFND | 3,5 | 0 | 1,851,801 | 0 | |
| Kaleido Biosciences Inc | COM | 483347100 | 88,816 | 9,759,979 | SH | DFND | 1,3 | 0 | 9,759,979 | 0 | |
| Kaleido Biosciences Inc | COM | 483347100 | 15,075 | 1,656,643 | SH | DFND | 2,3 | 0 | 1,656,643 | 0 | |
| Kaleido Biosciences Inc | COM | 483347100 | 26,490 | 2,910,972 | SH | DFND | 3,4 | 0 | 2,910,972 | 0 | |
| Kaleido Biosciences Inc | COM | 483347100 | 6,067 | 666,666 | SH | DFND | 3,6 | 0 | 666,666 | 0 | |
| Kaleido Biosciences Inc | COM | 483347100 | 39,735 | 4,366,450 | SH | DFND | 3 | 0 | 4,366,450 | 0 | |
| Moderna Inc | COM | 60770K107 | 3,224,738 | 30,867,600 | SH | DFND | 2,3 | 0 | 30,867,600 | 0 | |
| Moderna Inc | COM | 60770K107 | 410 | 3,924 | SH | DFND | 3 | 0 | 3,924 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 87,883 | 11,578,828 | SH | DFND | 1,3 | 0 | 11,578,828 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 183,329 | 24,153,995 | SH | DFND | 2,3 | 0 | 24,153,995 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 19,459 | 2,563,703 | SH | DFND | 3,4 | 0 | 2,563,703 | 0 | |
| Seres Therapeutics Inc | COM | 81750R102 | 207,095 | 8,452,876 | SH | DFND | 2,3 | 0 | 8,452,876 | 0 | |
| Seres Therapeutics Inc | COM | 81750R102 | 72,593 | 2,962,963 | SH | DFND | 3,7 | 0 | 2,962,963 | 0 | |
| Seres Therapeutics Inc | COM | 81750R102 | 79,824 | 3,258,134 | SH | DFND | 3,6 | 0 | 3,258,134 | 0 | |
| Sigilon Therapeutics Inc | COM | 82657L107 | 426,933 | 8,888,888 | SH | DFND | 1,3 | 0 | 8,888,888 | 0 | |
| Sigilon Therapeutics Inc | COM | 82657L107 | 71,156 | 1,481,481 | SH | DFND | 3,5 | 0 | 1,481,481 | 0 | |
| Syros Pharmaceuticals Inc | COM | 87184Q107 | 31,883 | 2,938,494 | SH | DFND | 2,3 | 0 | 2,938,494 | 0 | |