The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101 1,836 11,462 SH   SOLE   11,462 0 0
ABBOTT LABS COM 002824100 2,612 24,001 SH   SOLE   24,001 0 0
ABBVIE INC COM 00287Y109 3,432 39,187 SH   SOLE   39,187 0 0
ABERDEEN STD GOLD ETF TR PHYSCL GOLD SHS 00326A104 449 24,740 SH   SOLE   24,740 0 0
ABIOMED INC COM 003654100 22,624 81,658 SH   SOLE   81,658 0 0
ACCELERATE DIAGNOSTICS INC COM 00430H102 20,967 1,966,891 SH   SOLE   1,966,891 0 0
ACCENTURE PLC IRELAND SHS CLASS A G1151C101 788 3,485 SH   SOLE   3,485 0 0
ADOBE SYSTEMS INCORPORATED COM 00724F101 3,541 7,220 SH   SOLE   7,220 0 0
AIR PRODS & CHEMS INC COM 009158106 837 2,810 SH   SOLE   2,810 0 0
ALBIREO PHARMA INC COM 01345P106 17,033 510,443 SH   SOLE   510,443 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 553 1,880 SH   SOLE   1,880 0 0
ALIGN TECHNOLOGY INC COM 016255101 854 2,609 SH   SOLE   2,609 0 0
ALLIANCE DATA SYSTEMS CORP COM 018581108 4,822 114,861 SH   SOLE   114,861 0 0
ALLIANT ENERGY CORP COM 018802108 1,128 21,834 SH   SOLE   21,834 0 0
ALPHABET INC CAP STK CL A 02079K305 44,856 30,606 SH   SOLE   30,606 0 0
ALPHABET INC CAP STK CL C 02079K107 2,293 1,560 SH   SOLE   1,560 0 0
ALTRIA GROUP INC COM 02209S103 609 15,767 SH   SOLE   15,767 0 0
AMAZON COM INC COM 023135106 58,228 18,492 SH   SOLE   18,492 0 0
AMERICAN ELEC PWR CO INC COM 025537101 637 7,790 SH   SOLE   7,790 0 0
AMERICAN EXPRESS CO COM 025816109 1,083 10,804 SH   SOLE   10,804 0 0
AMERICAN TOWER CORP NEW COM 03027X100 1,940 8,024 SH   SOLE   8,024 0 0
AMGEN INC COM 031162100 3,129 12,311 SH   SOLE   12,311 0 0
ANTHEM INC COM 036752103 537 2,000 SH   SOLE   2,000 0 0
AON PLC SHS CL A G0403H108 536 2,600 SH   SOLE   2,600 0 0
APACHE CORP COM 037411105 142 15,000 SH   SOLE   15,000 0 0
APPLE INC COM 037833100 72,460 625,682 SH   SOLE   625,682 0 0
ARCHER DANIELS MIDLAND CO COM 039483102 323 6,937 SH   SOLE   6,937 0 0
AT&T INC COM 00206R102 2,024 70,979 SH   SOLE   70,979 0 0
ATLASSIAN CORP PLC CL A G06242104 288 1,585 SH   SOLE   1,585 0 0
AUTOMATIC DATA PROCESSING IN COM 053015103 887 6,357 SH   SOLE   6,357 0 0
BALL CORP COM 058498106 399 4,800 SH   SOLE   4,800 0 0
BAXTER INTL INC COM 071813109 702 8,733 SH   SOLE   8,733 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 10,419 48,929 SH   SOLE   48,929 0 0
BERKSHIRE HATHAWAY INC DEL CL A 084670108 960 3 SH   SOLE   3 0 0
BIO-TECHNE CORP COM 09073M104 248 1,000 SH   SOLE   1,000 0 0
BK OF AMERICA CORP COM 060505104 331 13,747 SH   SOLE   13,747 0 0
BLACKLINE INC COM 09239B109 49,767 555,248 SH   SOLE   555,248 0 0
BOEING CO COM 097023105 569 3,440 SH   SOLE   3,440 0 0
BP PLC SPONSORED ADR 055622104 572 32,747 SH   SOLE   32,747 0 0
BRIGHT HORIZONS FAM SOL IN D COM 109194100 289 1,900 SH   SOLE   1,900 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 2,109 34,976 SH   SOLE   34,976 0 0
BURLINGTON STORES INC COM 122017106 273 1,326 SH   SOLE   1,326 0 0
C H ROBINSON WORLDWIDE INC COM NEW 12541W209 245 2,400 SH   SOLE   2,400 0 0
CARRIER GLOBAL CORPORATION COM 14448C104 447 14,625 SH   SOLE   14,625 0 0
CARVANA CO CL A 146869102 40,589 181,963 SH   SOLE   181,963 0 0
CATERPILLAR INC DEL COM 149123101 618 4,145 SH   SOLE   4,145 0 0
CHAMPIONX CORPORATION COM 15872M104 81 10,196 SH   SOLE   10,196 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 258 413 SH   SOLE   413 0 0
CHEGG INC COM 163092109 230 3,214 SH   SOLE   3,214 0 0
CHEVRON CORP NEW COM 166764100 738 10,246 SH   SOLE   10,246 0 0
CHIMERA INVT CORP COM NEW 16934Q208 176 21,500 SH   SOLE   21,500 0 0
CIGNA CORP NEW COM 125523100 260 1,533 SH   SOLE   1,533 0 0
CINTAS CORP COM 172908105 271 814 SH   SOLE   814 0 0
CISCO SYS INC COM 17275R102 1,886 47,878 SH   SOLE   47,878 0 0
CME GROUP INC COM 12572Q105 986 5,896 SH   SOLE   5,896 0 0
COCA COLA CO COM 191216100 3,498 70,850 SH   SOLE   70,850 0 0
COMCAST CORP NEW CL A 20030N101 1,286 27,801 SH   SOLE   27,801 0 0
CONSTELLATION BRANDS INC CL A 21036P108 311 1,640 SH   SOLE   1,640 0 0
COPART INC COM 217204106 3,134 29,800 SH   SOLE   29,800 0 0
CORNING INC COM 219350105 301 9,273 SH   SOLE   9,273 0 0
COSTAR GROUP INC COM 22160N109 41,128 48,471 SH   SOLE   48,471 0 0
COSTCO WHSL CORP NEW COM 22160K105 42,050 118,450 SH   SOLE   118,450 0 0
DANAHER CORPORATION COM 235851102 703 3,267 SH   SOLE   3,267 0 0
DEERE & CO COM 244199105 421 1,900 SH   SOLE   1,900 0 0
DEXCOM INC COM 252131107 57,849 140,330 SH   SOLE   140,330 0 0
DIREXION SHS ETF TR DLY FIN BULL NEW 25459Y694 244 7,200 SH   SOLE   7,200 0 0
DISNEY WALT CO COM DISNEY 254687106 1,018 8,202 SH   SOLE   8,202 0 0
DNP SELECT INCOME FD INC COM 23325P104 103 10,215 SH   SOLE   10,215 0 0
DOMINION ENERGY INC COM 25746U109 442 5,594 SH   SOLE   5,594 0 0
DTE ENERGY CO COM 233331107 402 3,495 SH   SOLE   3,495 0 0
DUKE ENERGY CORP NEW COM NEW 26441C204 737 8,326 SH   SOLE   8,326 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 16,980 3,930,524 SH   SOLE   3,930,524 0 0
EBAY INC. COM 278642103 205 3,940 SH   SOLE   3,940 0 0
ECOLAB INC COM 278865100 2,429 12,157 SH   SOLE   12,157 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 27,762 347,804 SH   SOLE   347,804 0 0
EMERSON ELEC CO COM 291011104 420 6,406 SH   SOLE   6,406 0 0
ENBRIDGE INC COM 29250N105 211 7,234 SH   SOLE   7,234 0 0
ENDURANCE INTL GROUP HLDGS I COM 29272B105 4,430 771,705 SH   SOLE   771,705 0 0
ENTERGY CORP NEW COM 29364G103 245 2,489 SH   SOLE   2,489 0 0
ENTERPRISE PRODS PARTNERS L COM 293792107 356 22,518 SH   SOLE   22,518 0 0
EQUINIX INC COM 29444U700 1,424 1,874 SH   SOLE   1,874 0 0
ETSY INC COM 29786A106 271 2,225 SH   SOLE   2,225 0 0
EVO PMTS INC CL A COM 26927E104 622 25,029 SH   SOLE   25,029 0 0
EVOLENT HEALTH INC CL A 30050B101 125 10,073 SH   SOLE   10,073 0 0
EXELIXIS INC COM 30161Q104 20,319 831,051 SH   SOLE   831,051 0 0
EXXON MOBIL CORP COM 30231G102 10,907 317,716 SH   SOLE   317,716 0 0
F M C CORP COM NEW 302491303 525 4,957 SH   SOLE   4,957 0 0
FACEBOOK INC CL A 30303M102 48,477 185,099 SH   SOLE   185,099 0 0
FAIR ISAAC CORP COM 303250104 39,977 93,978 SH   SOLE   93,978 0 0
FASTENAL CO COM 311900104 22,350 495,676 SH   SOLE   495,676 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 463 3,147 SH   SOLE   3,147 0 0
FIFTH THIRD BANCORP COM 316773100 695 32,578 SH   SOLE   32,578 0 0
GARTNER INC COM 366651107 275 2,200 SH   SOLE   2,200 0 0
GENERAL ELECTRIC CO COM 369604103 1,028 165,069 SH   SOLE   165,069 0 0
GENERAL MLS INC COM 370334104 760 12,322 SH   SOLE   12,322 0 0
GILEAD SCIENCES INC COM 375558103 259 4,092 SH   SOLE   4,092 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 415 11,021 SH   SOLE   11,021 0 0
GLOBAL PMTS INC COM 37940X102 7,408 41,719 SH   SOLE   41,719 0 0
GRAINGER W W INC COM 384802104 866 2,428 SH   SOLE   2,428 0 0
GUARDANT HEALTH INC COM 40131M109 28,177 252,076 SH   SOLE   252,076 0 0
HOME DEPOT INC COM 437076102 2,238 8,058 SH   SOLE   8,058 0 0
HONEYWELL INTL INC COM 438516106 1,672 10,156 SH   SOLE   10,156 0 0
IDEXX LABS INC COM 45168D104 35,556 90,446 SH   SOLE   90,446 0 0
IHS MARKIT LTD SHS G47567105 799 10,180 SH   SOLE   10,180 0 0
ILLINOIS TOOL WKS INC COM 452308109 5,323 27,550 SH   SOLE   27,550 0 0
ILLUMINA INC COM 452327109 1,350 4,368 SH   SOLE   4,368 0 0
INOGEN INC COM 45780L104 204 7,047 SH   SOLE   7,047 0 0
INTEL CORP COM 458140100 2,321 44,831 SH   SOLE   44,831 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 56,085 560,568 SH   SOLE   560,568 0 0
INTERNATIONAL BUSINESS MACHS COM 459200101 1,009 8,292 SH   SOLE   8,292 0 0
INTUIT COM 461202103 3,961 12,142 SH   SOLE   12,142 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 1,276 1,799 SH   SOLE   1,799 0 0
INVESCO QQQ TR UNIT SER 1 46090E103 1,131 4,069 SH   SOLE   4,069 0 0
IQVIA HLDGS INC COM 46266C105 552 3,500 SH   SOLE   3,500 0 0
IRON MTN INC NEW COM 46284V101 2,669 99,612 SH   SOLE   99,612 0 0
ISHARES TR RUS 2000 GRW ETF 464287648 768 3,467 SH   SOLE   3,467 0 0
ISHARES TR RUSSELL 2000 ETF 464287655 793 5,295 SH   SOLE   5,295 0 0
ISHARES TR RUS 1000 GRW ETF 464287614 853 3,934 SH   SOLE   3,934 0 0
ISHARES TR CORE S&P500 ETF 464287200 5,198 15,468 SH   SOLE   15,468 0 0
J2 GLOBAL INC COM 48123V102 47,246 682,543 SH   SOLE   682,543 0 0
JOHNSON & JOHNSON COM 478160104 9,798 65,814 SH   SOLE   65,814 0 0
JPMORGAN CHASE & CO COM 46625H100 5,802 60,264 SH   SOLE   60,264 0 0
KELLOGG CO COM 487836108 385 5,960 SH   SOLE   5,960 0 0
KIMBERLY CLARK CORP COM 494368103 997 6,749 SH   SOLE   6,749 0 0
KORNIT DIGITAL LTD SHS M6372Q113 54,642 842,337 SH   SOLE   842,337 0 0
LAUDER ESTEE COS INC CL A 518439104 991 4,539 SH   SOLE   4,539 0 0
LIGAND PHARMACEUTICALS INC COM NEW 53220K504 46,310 485,842 SH   SOLE   485,842 0 0
LILLY ELI & CO COM 532457108 3,146 21,257 SH   SOLE   21,257 0 0
LINDE PLC SHS G5494J103 438 1,840 SH   SOLE   1,840 0 0
LOCKHEED MARTIN CORP COM 539830109 455 1,186 SH   SOLE   1,186 0 0
LOWES COS INC COM 548661107 57,881 348,972 SH   SOLE   348,972 0 0
LULULEMON ATHLETICA INC COM 550021109 3,367 10,223 SH   SOLE   10,223 0 0
LYFT INC CL A COM 55087P104 1,046 37,959 SH   SOLE   37,959 0 0
MARRIOTT INTL INC NEW CL A 571903202 415 4,479 SH   SOLE   4,479 0 0
MARSH & MCLENNAN COS INC COM 571748102 367 3,200 SH   SOLE   3,200 0 0
MASTERCARD INCORPORATED CL A 57636Q104 12,019 35,540 SH   SOLE   35,540 0 0
MATCH GROUP INC NEW COM 57667L107 314 2,838 SH   SOLE   2,838 0 0
MCCORMICK & CO INC COM NON VTG 579780206 371 1,912 SH   SOLE   1,912 0 0
MCDONALDS CORP COM 580135101 1,962 8,941 SH   SOLE   8,941 0 0
MERCADOLIBRE INC COM 58733R102 4,151 3,835 SH   SOLE   3,835 0 0
MERCK & CO. INC COM 58933Y105 1,497 18,045 SH   SOLE   18,045 0 0
MICROCHIP TECHNOLOGY INC. COM 595017104 253 2,462 SH   SOLE   2,462 0 0
MICROSOFT CORP COM 594918104 22,768 108,247 SH   SOLE   108,247 0 0
MORNINGSTAR INC COM 617700109 21,697 135,090 SH   SOLE   135,090 0 0
NAUTILUS INC COM 63910B102 204 11,891 SH   SOLE   11,891 0 0
NETFLIX INC COM 64110L106 4,221 8,441 SH   SOLE   8,441 0 0
NEXTERA ENERGY INC COM 65339F101 279 1,005 SH   SOLE   1,005 0 0
NIKE INC CL B 654106103 2,219 17,675 SH   SOLE   17,675 0 0
NORFOLK SOUTHN CORP COM 655844108 278 1,300 SH   SOLE   1,300 0 0
NORTHERN TR CORP COM 665859104 1,148 14,719 SH   SOLE   14,719 0 0
NOVARTIS AG SPONSORED ADR 66987V109 230 2,640 SH   SOLE   2,640 0 0
NVIDIA CORPORATION COM 67066G104 3,955 7,307 SH   SOLE   7,307 0 0
OGE ENERGY CORP COM 670837103 279 9,300 SH   SOLE   9,300 0 0
ORACLE CORP COM 68389X105 1,092 18,293 SH   SOLE   18,293 0 0
OREILLY AUTOMOTIVE INC COM 67103H107 1,162 2,520 SH   SOLE   2,520 0 0
OTIS WORLDWIDE CORP COM 68902V107 492 7,884 SH   SOLE   7,884 0 0
PACKAGING CORP AMER COM 695156109 593 5,434 SH   SOLE   5,434 0 0
PAPA JOHNS INTL INC COM 698813102 571 6,936 SH   SOLE   6,936 0 0
PAYCHEX INC COM 704326107 3,108 38,966 SH   SOLE   38,966 0 0
PAYLOCITY HLDG CORP COM 70438V106 404 2,500 SH   SOLE   2,500 0 0
PAYPAL HLDGS INC COM 70450Y103 55,579 282,084 SH   SOLE   282,084 0 0
PEPSICO INC COM 713448108 5,957 42,979 SH   SOLE   42,979 0 0
PFIZER INC COM 717081103 2,672 72,800 SH   SOLE   72,800 0 0
PINTEREST INC CL A 72352L106 37,222 896,695 SH   SOLE   896,695 0 0
POOL CORP COM 73278L105 308 920 SH   SOLE   920 0 0
PRA GROUP INC COM 69354N106 260 6,520 SH   SOLE   6,520 0 0
PROCTER AND GAMBLE CO COM 742718109 5,108 36,748 SH   SOLE   36,748 0 0
PROGRESSIVE CORP COM 743315103 56,277 594,452 SH   SOLE   594,452 0 0
PROTO LABS INC COM 743713109 737 5,690 SH   SOLE   5,690 0 0
QUALCOMM INC COM 747525103 324 2,750 SH   SOLE   2,750 0 0
QUINSTREET INC COM 74874Q100 33,200 2,095,934 SH   SOLE   2,095,934 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 1,075 18,684 SH   SOLE   18,684 0 0
REALPAGE INC COM 75606N109 34,066 591,014 SH   SOLE   591,014 0 0
S&P GLOBAL INC COM 78409V104 926 2,569 SH   SOLE   2,569 0 0
SALESFORCE COM INC COM 79466L302 53,994 214,841 SH   SOLE   214,841 0 0
SHOPIFY INC CL A 82509L107 15,469 15,122 SH   SOLE   15,122 0 0
SNAP INC CL A 83304A106 1,019 39,033 SH   SOLE   39,033 0 0
SOUTHERN CO COM 842587107 274 5,058 SH   SOLE   5,058 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 1,575 4,703 SH   SOLE   4,703 0 0
SPROTT PHYSICAL GOLD & SILVE TR UNIT 85208R101 2,467 134,520 SH   SOLE   134,520 0 0
SPROTT PHYSICAL GOLD TR UNIT 85207H104 2,769 183,978 SH   SOLE   183,978 0 0
SPROTT PHYSICAL SILVER TR TR UNIT 85207K107 132 16,000 SH   SOLE   16,000 0 0
STARBUCKS CORP COM 855244109 1,699 19,772 SH   SOLE   19,772 0 0
STATE STR CORP COM 857477103 381 6,423 SH   SOLE   6,423 0 0
STRYKER CORPORATION COM 863667101 706 3,386 SH   SOLE   3,386 0 0
SVB FINANCIAL GROUP COM 78486Q101 39,845 165,594 SH   SOLE   165,594 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 16,757 206,696 SH   SOLE   206,696 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 266 1,610 SH   SOLE   1,610 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 49,978 440,334 SH   SOLE   440,334 0 0
TARGET CORP COM 87612E106 55,771 354,282 SH   SOLE   354,282 0 0
TELADOC HEALTH INC COM 87918A105 4,322 19,715 SH   SOLE   19,715 0 0
TELEFLEX INCORPORATED COM 879369106 851 2,500 SH   SOLE   2,500 0 0
TESLA INC COM 88160R101 521 1,214 SH   SOLE   1,214 0 0
TEXAS INSTRS INC COM 882508104 477 3,340 SH   SOLE   3,340 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 383 867 SH   SOLE   867 0 0
TJX COS INC NEW COM 872540109 543 9,765 SH   SOLE   9,765 0 0
TRANSDIGM GROUP INC COM 893641100 1,093 2,300 SH   SOLE   2,300 0 0
TRANSUNION COM 89400J107 24,464 290,786 SH   SOLE   290,786 0 0
ULTA BEAUTY INC COM 90384S303 365 1,630 SH   SOLE   1,630 0 0
UNILEVER N V N Y SHS NEW 904784709 444 7,351 SH   SOLE   7,351 0 0
UNION PAC CORP COM 907818108 1,190 6,044 SH   SOLE   6,044 0 0
UNITED PARCEL SERVICE INC CL B 911312106 681 4,089 SH   SOLE   4,089 0 0
US BANCORP DEL COM NEW 902973304 388 10,826 SH   SOLE   10,826 0 0
VALMONT INDS INC COM 920253101 579 4,662 SH   SOLE   4,662 0 0
VANGUARD INDEX FDS S&P 500 ETF SHS 922908363 254 825 SH   SOLE   825 0 0
VANGUARD INTL EQUITY INDEX F FTSE EUROPE ETF 922042874 1,049 20,000 SH   SOLE   20,000 0 0
VANGUARD SCOTTSDALE FDS SHRT TRM CORP BD 92206C409 450 5,428 SH   SOLE   5,428 0 0
VEEVA SYS INC CL A COM 922475108 47,137 167,635 SH   SOLE   167,635 0 0
VERISK ANALYTICS INC COM 92345Y106 463 2,500 SH   SOLE   2,500 0 0
VERIZON COMMUNICATIONS INC COM 92343V104 2,709 45,543 SH   SOLE   45,543 0 0
VISA INC COM CL A 92826C839 64,916 324,628 SH   SOLE   324,628 0 0
VULCAN MATLS CO COM 929160109 218 1,609 SH   SOLE   1,609 0 0
WAITR HLDGS INC COM 930752100 148 46,080 SH   SOLE   46,080 0 0
WALGREENS BOOTS ALLIANCE INC COM 931427108 594 16,526 SH   SOLE   16,526 0 0
WALMART INC COM 931142103 797 5,694 SH   SOLE   5,694 0 0
WASTE MGMT INC DEL COM 94106L109 694 6,132 SH   SOLE   6,132 0 0
WEC ENERGY GROUP INC COM 92939U106 673 6,941 SH   SOLE   6,941 0 0
WELLS FARGO CO NEW COM 949746101 439 18,654 SH   SOLE   18,654 0 0
WEX INC COM 96208T104 231 1,660 SH   SOLE   1,660 0 0
WEYERHAEUSER CO MTN BE COM NEW 962166104 337 11,813 SH   SOLE   11,813 0 0
WIX COM LTD SHS M98068105 382 1,500 SH   SOLE   1,500 0 0
WORKDAY INC CL A 98138H101 32,738 152,177 SH   SOLE   152,177 0 0
YUM BRANDS INC COM 988498101 1,103 12,086 SH   SOLE   12,086 0 0
YUM CHINA HLDGS INC COM 98850P109 558 10,541 SH   SOLE   10,541 0 0
ZEBRA TECHNOLOGIES CORPORATI CL A 989207105 8,989 35,606 SH   SOLE   35,606 0 0
ZOETIS INC CL A 98978V103 47,832 289,245 SH   SOLE   289,245 0 0