The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
58 COM INC SPON ADR REP A 31680Q104 267,824 4,965,212 SH   OTR   4,965,212 0 0
ABBVIE INC COM 00287Y109 407,447 4,150,000 SH   OTR   4,150,000 0 0
ACCELERON PHARMA INC COM 00434H108 200,067 2,100,000 SH   OTR   2,100,000 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 25,025 2,500,000 SH   OTR   2,500,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 66,850 1,250,000 SH   OTR   1,250,000 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 10,185 750,000 SH   OTR   750,000 0 0
AKOUOS INC COM 00973J101 5,063 225,000 SH   OTR   225,000 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 199,889 926,700 SH   OTR   926,700 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 155,516 1,050,000 SH   OTR   1,050,000 0 0
ALPHABET INC CAP STK CL C 02079K107 312,478 221,050 SH   OTR   221,050 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 21,625 3,125,000 SH   OTR   3,125,000 0 0
AMYRIS INC COM NEW 03236M200 29,931 7,009,527 SH   OTR   7,009,527 0 0
ANTHEM INC COM 036752103 328,725 1,250,000 SH   OTR   1,250,000 0 0
AON PLC SHS CL A G0403H108 331,368 1,720,498 SH   OTR   1,720,498 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 73,485 2,250,000 SH   OTR   2,250,000 0 0
APPLIED MOLECULAR TRANS INC COM 03824M109 5,028 200,000 SH   OTR   200,000 0 0
ARCUS BIOSCIENCES INC COM 03969F109 24,740 1,000,000 SH   OTR   1,000,000 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 56,655 900,000 SH   OTR   900,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 34,552 800,000 SH   OTR   800,000 0 0
ARYA SCIENCES ACQUISTION CO UNIT 06/09/2027 G31655114 4,640 400,000 SH   OTR   400,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 168,606 1,140,000 SH   OTR   1,140,000 0 0
ATENTO S A SHS L0427L105 7,712 11,212,205 SH   OTR   11,212,205 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 1,413 50,000 SH   OTR   50,000 0 0
AVROBIO INC COM 05455M100 27,484 1,575,000 SH   OTR   1,575,000 0 0
BLACKSTONE GROUP INC COM CL A 09260D107 156,853 2,768,319 SH   OTR   2,768,319 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 213,150 3,625,000 SH   OTR   3,625,000 0 0
BRISTOL-MYERS SQUIBB CO RIGHT 99/99/9999 110122157 158,236 44,200,000 SH   OTR   44,200,000 0 0
BROADMARK RLTY CAP INC COM 11135B100 67,902 7,170,213 SH   OTR   7,170,213 0 0
BROADMARK RLTY CAP INC COM 11135B100 22,648 2,391,536 SH Call OTR   2,391,536 0 0
BROADMARK RLTY CAP INC *W EXP 11/15/202 11135B118 2,281 7,174,613 SH   OTR   7,174,613 0 0
CARA THERAPEUTICS INC COM 140755109 39,330 2,300,000 SH   OTR   2,300,000 0 0
CAESARS ENTMT CORP COM 127686103 97,222 8,015,000 SH   OTR   8,015,000 0 0
CENTENE CORP DEL COM 15135B101 444,850 7,000,000 SH   OTR   7,000,000 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 385,088 755,015 SH   OTR   755,015 0 0
CIGNA CORP NEW COM 125523100 93,825 500,000 SH   OTR   500,000 0 0
CLOVIS ONCOLOGY INC NOTE 1.250% 5/0 189464AC4 31,197 51,672,000 PRN   OTR   51,672,000 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 10,518 350,000 SH   OTR   350,000 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 11,024 150,000 SH   OTR   150,000 0 0
CTRIP COM INTL LTD DBCV 1.990% 7/0 22943FAH3 3,483 3,508,000 PRN   OTR   3,508,000 0 0
CYTOKINETICS INC COM NEW 23282W605 35,355 1,500,000 SH   OTR   1,500,000 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 1,241 148,952 SH   OTR   148,952 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 42,700 715,000 SH   OTR   715,000 0 0
DERMTECH INC COM 24984K105 2,576 194,675 SH   OTR   194,675 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 87,868 1,750,000 SH   OTR   1,750,000 0 0
EQUIFAX INC COM 294429105 43,889 255,344 SH   OTR   255,344 0 0
EQUINIX INC COM 29444U700 187,933 267,597 SH   OTR   267,597 0 0
EXELIXIS INC COM 30161Q104 243,335 10,250,000 SH   OTR   10,250,000 0 0
FACEBOOK INC CL A 30303M102 308,473 1,358,494 SH   OTR   1,358,494 0 0
FATE THERAPEUTICS INC COM 31189P102 120,085 3,500,000 SH   OTR   3,500,000 0 0
FIBROGEN INC COM 31572Q808 65,861 1,625,000 SH   OTR   1,625,000 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 481,400 3,590,128 SH   OTR   3,590,128 0 0
FORESCOUT TECHNOLOGIES INC COM 34553D101 27,666 1,305,000 SH   OTR   1,305,000 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 4,368 250,000 SH   OTR   250,000 0 0
GENERAL DYNAMICS CORP COM 369550108 172,100 1,151,481 SH   OTR   1,151,481 0 0
GENERATION BIO CO COM 37148K100 44,495 2,118,819 SH   OTR   2,118,819 0 0
GOL LINHAS AEREAS INTELIGENT SPON ADR PFD NEW 38045R206 582 85,838 SH   OTR   85,838 0 0
GOSSAMER BIO INC COM 38341P102 1,300 100,000 SH   OTR   100,000 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 20,022 20,000,000 PRN   OTR   20,000,000 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 56,785 3,113,222 SH   OTR 1 3,113,222 0 0
HORIZON PHARMA INVT LTD NOTE 2.500% 3/1 44052TAB7 29,367 15,047,000 PRN   OTR   15,047,000 0 0
HOWMET AEROSPACE INC COM 443201108 19,007 1,199,186 SH   OTR   1,199,186 0 0
IAC INTERACTIVECORP COM 44919P508 455,994 1,410,000 SH   OTR   1,410,000 0 0
IHS MARKIT LTD SHS G47567105 295,207 3,910,024 SH   OTR   3,910,024 0 0
INTERCEPT PHARMACEUTICALS IN NOTE 3.250% 7/0 45845PAA6 4,822 6,500,000 PRN   OTR   6,500,000 0 0
INTERCEPT PHARMACEUTICALS IN NOTE 2.000% 5/1 45845PAB4 18,998 25,500,000 PRN   OTR   25,500,000 0 0
INVITAE CORP COM 46185L103 19,886 656,528 SH   OTR   656,528 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 179,454 6,537,500 SH   OTR   6,537,500 0 0
IQIYI INC NOTE 3.750%12/0 46267XAB4 33,097 29,500,000 PRN   OTR   29,500,000 0 0
IQIYI INC NOTE 2.000% 4/0 46267XAD0 61,445 61,438,000 PRN   OTR   61,438,000 0 0
IQVIA HLDGS INC COM 46266C105 538,581 3,796,030 SH   OTR   3,796,030 0 0
ISHARES TR CHINA LG-CAP ETF 464287184 22,331 562,500 SH Put OTR   562,500 0 0
IVERIC BIO INC COM 46583P102 3,825 750,000 SH   OTR   750,000 0 0
KARUNA THERAPEUTICS INC COM 48576A100 64,090 575,000 SH   OTR   575,000 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 25,285 1,335,000 SH   OTR   1,335,000 0 0
KARYOPHARM THERAPEUTICS INC NOTE 3.000%10/1 48576UAA4 50,287 35,102,000 PRN   OTR   35,102,000 0 0
KRYSTAL BIOTECH INC COM 501147102 18,639 450,000 SH   OTR   450,000 0 0
LANTHEUS HLDGS INC COM 516544103 37,680 2,634,999 SH   OTR   2,634,999 0 0
LIQUIDIA TECHNOLOGIES INC COM 53635D202 15,577 1,850,000 SH   OTR   1,850,000 0 0
MICROSOFT CORP COM 594918104 311,004 1,528,199 SH   OTR   1,528,199 0 0
MIRATI THERAPEUTICS INC COM 60468T105 74,211 650,000 SH   OTR   650,000 0 0
MOMO INC NOTE 1.250% 7/0 60879BAB3 64,159 81,601,000 PRN   OTR   81,601,000 0 0
MYOKARDIA INC COM 62857M105 84,543 875,000 SH   OTR   875,000 0 0
NEW ORIENTAL ED & TECHNOLOGY SPON ADR 647581107 82,175 631,000 SH   OTR   631,000 0 0
NEW YORK TIMES CO CL A 650111107 173,901 4,137,542 SH   OTR   4,137,542 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 10,350 3,000,000 SH   OTR   3,000,000 0 0
PALO ALTO NETWORKS INC COM 697435105 195,703 852,105 SH   OTR   852,105 0 0
PLAYA HOTELS & RESORTS NV SHS N70544106 110,797 30,606,930 SH   OTR   30,606,930 0 0
PLIANT THERAPEUTICS INC COM 729139105 27,617 850,801 SH   OTR   850,801 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 33,187 1,844,757 SH   OTR   1,844,757 0 0
PRINCIPIA BIOPHARMA INC COM 74257L108 17,937 300,000 SH   OTR   300,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 44,150 2,500,000 SH   OTR   2,500,000 0 0
QIAGEN NV SHS NEW N72482123 123,336 2,881,000 SH   OTR   2,881,000 0 0
RADIUS HEALTH INC COM NEW 750469207 28,623 2,100,000 SH   OTR   2,100,000 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 5,009 6,750,000 PRN   OTR   6,750,000 0 0
READY CAPITAL CORP COM 75574U101 11,733 1,350,226 SH   OTR   1,350,226 0 0
REPARE THERAPEUTICS INC COM 760273102 4,653 150,000 SH   OTR   150,000 0 0
ROYALTY PHARMA PLC SHS CL A G7709Q104 13,351 275,000 SH   OTR   275,000 0 0
SAGE THERAPEUTICS INC COM 78667J108 35,343 850,000 SH   OTR   850,000 0 0
SALESFORCE COM INC COM 79466L302 285,800 1,525,648 SH   OTR   1,525,648 0 0
SAREPTA THERAPEUTICS INC COM 803607100 84,179 525,000 SH   OTR   525,000 0 0
SAVARA INC COM 805111101 11,133 4,470,964 SH   OTR   4,470,964 0 0
SHERWIN WILLIAMS CO COM 824348106 258,869 447,987 SH   OTR   447,987 0 0
TG THERAPEUTICS INC COM 88322Q108 29,220 1,500,000 SH   OTR   1,500,000 0 0
THERAVANCE BIOPHARMA INC NOTE 3.250%11/0 88339KAA0 40,869 41,905,000 PRN   OTR   41,905,000 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 387,524 1,069,505 SH   OTR   1,069,505 0 0
T-MOBILE US INC COM 872590104 360,112 3,457,631 SH   OTR   3,457,631 0 0
TRANSUNION COM 89400J107 103,817 1,192,747 SH   OTR   1,192,747 0 0
TRICIDA INC COM 89610F101 13,740 500,000 SH   OTR   500,000 0 0
UNIQURE NV SHS N90064101 13,518 300,000 SH   OTR   300,000 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 42,350 350,000 SH   OTR   350,000 0 0
VERACYTE INC COM 92337F107 22,015 850,000 SH   OTR   850,000 0 0
VISA INC COM CL A 92826C839 347,585 1,799,373 SH   OTR   1,799,373 0 0
WABTEC COM 929740108 249,011 4,325,361 SH   OTR   4,325,361 0 0
ZEALAND PHARMA A S SPONSORED ADR 98920Y304 17,500 500,000 SH   OTR   500,000 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 47,596 991,174 SH   OTR   991,174 0 0
ZOGENIX INC COM NEW 98978L204 54,020 2,000,000 SH   OTR   2,000,000 0 0
ZYMEWORKS INC COM 98985W102 19,839 550,000 SH   OTR   550,000 0 0