The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AGNC INVT CORP COM 00123Q104 254,330 19,715,474 SH   DFND 1, 2 19,715,474 0 0
AES CORP COM 00130H105 1,176,817 81,215,783 SH   DFND 1, 2 81,215,783 0 0
ABBOTT LABS COM 002824100 252,343 2,760,099 SH   DFND 1, 2 2,754,815 0 5,284
ACACIA COMMUNICATIONS INC COM 00401C108 25,532 380,000 SH   DFND 1, 2 380,000 0 0
ACTIVISION BLIZZARD INC COM 00507V109 2,888,753 38,060,002 SH   DFND 1, 2 38,057,769 0 2,233
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 80,107 8,002,700 SH   DFND 1, 2 8,002,700 0 0
ADDUS HOMECARE CORP COM 006739106 26,842 290,000 SH   DFND 1, 2 290,000 0 0
ADOBE INC COM 00724F101 1,129,164 2,593,965 SH   DFND 1, 2 2,592,582 0 1,383
AEROJET ROCKETDYNE HLDGS INC COM 007800105 17,843 450,126 SH   DFND 1, 2 450,126 0 0
ADVANCED MICRO DEVICES INC COM 007903107 2,431,825 46,223,845 SH   DFND 1, 2 46,219,110 0 4,735
AFFILIATED MANAGERS GROUP IN COM 008252108 8,798 118,000 SH   DFND 1, 2 118,000 0 0
AGORA INC ADS 00851L103 65,372 1,480,000 SH   DFND 1, 2 1,480,000 0 0
AIR PRODS & CHEMS INC COM 009158106 894,448 3,704,331 SH   DFND 1, 2 3,704,331 0 0
ALARM COM HLDGS INC COM 011642105 207,910 3,208,000 SH   DFND 1, 2 3,208,000 0 0
ALCOA CORP COM 013872106 10,228 910,000 SH   DFND 1, 2 910,000 0 0
ALEXANDRIA REAL ESTATE EQ IN COM 015271109 456,254 2,812,043 SH   DFND 1, 2 2,812,043 0 0
ALGONQUIN PWR UTILS CORP COM 015857105 159 12,285 SH   DFND 1, 2 12,285 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 2,148 9,991 SH   DFND 1, 2 6 0 9,985
ALLAKOS INC COM 01671P100 414,172 5,763,598 SH   DFND 1, 2 5,763,598 0 0
ALLEGHENY TECHNOLOGIES INC COM 01741R102 36,311 3,563,427 SH   DFND 1, 2 3,563,427 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 149,062 3,481,124 SH   DFND 1, 2 3,481,124 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 52,216 352,546 SH   DFND 1, 2 352,546 0 0
ALPHABET INC CAP STK CL C 02079K107 3,579,851 2,532,427 SH   DFND 1, 2 2,531,719 0 708
ALPHABET INC CAP STK CL A 02079K305 2,570,607 1,812,818 SH   DFND 1, 2 1,809,961 0 2,857
ALTERYX INC COM CL A 02156B103 801,021 4,875,980 SH   DFND 1, 2 4,874,583 0 1,397
ALTICE USA INC CL A 02156K103 73,571 3,264,023 SH   DFND 1, 2 3,264,023 0 0
ALTRIA GROUP INC COM 02209S103 3,799,535 96,803,443 SH   DFND 1, 2 96,803,443 0 0
AMAZON COM INC COM 023135106 11,546,546 4,185,361 SH   DFND 1, 2 4,183,933 0 1,428
AMERICA MOVIL SAB DE CV SPON ADR L SHS 02364W105 228,359 17,995,218 SH   DFND 1, 2 17,995,218 0 0
AMERICAN ELEC PWR CO INC COM 025537101 792,555 9,951,722 SH   DFND 1, 2 9,951,722 0 0
AMERICAN ELEC PWR CO INC UNIT 03/15/2022 025537127 120,322 2,485,480 SH   DFND 1, 2 2,485,480 0 0
AMERICAN TOWER CORP NEW COM 03027X100 2,517,147 9,736,007 SH   DFND 1, 2 9,736,007 0 0
AMPHENOL CORP NEW CL A 032095101 41,414 432,250 SH   DFND 1, 2 432,250 0 0
ANALOG DEVICES INC COM 032654105 618,266 5,041,310 SH   DFND 1, 2 5,041,310 0 0
APACHE CORP COM 037411105 33,460 2,478,500 SH   DFND 1, 2 2,478,500 0 0
APOLLO GLOBAL MGMT INC COM CL A 03768E105 561,343 11,244,856 SH   DFND 1, 2 11,244,856 0 0
APPLE INC COM 037833100 2,134,564 5,851,328 SH   DFND 1, 2 5,851,328 0 0
APPLIED MATLS INC COM 038222105 1,551,767 25,670,257 SH   DFND 1, 2 25,670,257 0 0
APPLIED MOLECULAR TRANS INC COM 03824M109 10,116 402,375 SH   DFND 1, 2 402,375 0 0
ARAMARK COM 03852U106 162,545 7,201,826 SH   DFND 1, 2 7,201,826 0 0
ARCHER DANIELS MIDLAND CO COM 039483102 387,751 9,718,071 SH   DFND 1, 2 9,718,071 0 0
ARES MANAGEMENT CORPORATION CL A COM STK 03990B101 405,539 10,215,079 SH   DFND 1, 2 10,215,079 0 0
ARGENX SE SPONSORED ADR 04016X101 149,014 661,606 SH   DFND 1, 2 661,606 0 0
ARISTA NETWORKS INC COM 040413106 448,136 2,133,677 SH   DFND 1, 2 2,133,677 0 0
ARTISAN PARTNERS ASSET MGMT CL A 04316A108 22,913 705,000 SH   DFND 1, 2 705,000 0 0
ASSETMARK FINL HLDGS INC COM 04546L106 61,403 2,250,000 SH   DFND 1, 2 2,250,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 291,420 5,509,907 SH   DFND 1, 2 5,457,302 0 52,605
AUTODESK INC COM 052769106 1,914,222 8,002,982 SH   DFND 1, 2 8,001,426 0 1,556
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 47,382 2,955,806 SH   DFND 1, 2 2,955,806 0 0
BCE INC COM NEW 05534B760 391 9,385 SH   DFND 1, 2 9,385 0 0
BP PLC SPONSORED ADR 055622104 47,012 2,015,950 SH   DFND 1, 2 2,015,950 0 0
BMC STK HLDGS INC COM 05591B109 14,562 579,222 SH   DFND 1, 2 579,222 0 0
BAKER HUGHES COMPANY CL A 05722G100 968,261 62,914,917 SH   DFND 1, 2 62,914,917 0 0
BANDWIDTH INC COM CL A 05988J103 95,631 753,000 SH   DFND 1, 2 753,000 0 0
BK OF AMERICA CORP COM 060505104 1,369,954 57,682,280 SH   DFND 1, 2 57,682,280 0 0
BANK NOVA SCOTIA B C COM 064149107 518,870 12,553,226 SH   DFND 1, 2 12,553,226 0 0
BARRICK GOLD CORPORATION COM 067901108 1,016,650 37,752,069 SH   DFND 1, 2 37,752,069 0 0
BARRETT BUSINESS SVCS INC COM 068463108 31,347 590,000 SH   DFND 1, 2 590,000 0 0
BAUSCH HEALTH COS INC COM 071734107 17,392 950,922 SH   DFND 1, 2 950,922 0 0
BEAZER HOMES USA INC COM NEW 07556Q881 16,714 1,659,813 SH   DFND 1, 2 1,659,813 0 0
BELLRING BRANDS INC COM CL A 079823100 19,940 1,000,000 SH   DFND 1, 2 1,000,000 0 0
BERKSHIRE HATHAWAY INC DEL CL A 084670108 362,192 1,355 SH   DFND 1, 2 1,355 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 2,201,726 12,333,910 SH   DFND 1, 2 12,333,910 0 0
BEYOND MEAT INC COM 08862E109 12,245 91,395 SH   DFND 1, 2 91,395 0 0
BIOGEN INC COM 09062X103 4,682 17,500 SH   DFND 1, 2 17,500 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105 22,134 525,000 SH   DFND 1, 2 525,000 0 0
BLACK KNIGHT INC COM 09215C105 8,562 118,000 SH   DFND 1, 2 118,000 0 0
BLACKLINE INC COM 09239B109 49,331 595,000 SH   DFND 1, 2 595,000 0 0
BLACKROCK INC COM 09247X101 3,835,610 7,049,676 SH   DFND 1, 2 7,045,338 0 4,338
BLACKSTONE GROUP INC COM CL A 09260D107 1,392,838 24,582,382 SH   DFND 1, 2 24,582,382 0 0
BLUEBIRD BIO INC COM 09609G100 211,857 3,470,784 SH   DFND 1, 2 3,470,784 0 0
BOEING CO COM 097023105 1,529,199 8,342,430 SH   DFND 1, 2 8,339,613 0 2,817
BOOKING HOLDINGS INC COM 09857L108 503,337 316,099 SH   DFND 1, 2 316,099 0 0
BOSTON PRIVATE FINL HLDGS IN COM 101119105 13,610 1,978,177 SH   DFND 1, 2 1,978,177 0 0
BOSTON SCIENTIFIC CORP COM 101137107 2,961,957 84,362,490 SH   DFND 1, 2 84,339,642 0 22,848
BOSTON SCIENTIFIC CORP 5.50% CNV PFD A 101137206 113,043 1,079,786 SH   DFND 1, 2 1,079,786 0 0
BOTTOMLINE TECH DEL INC COM 101388106 218,995 4,313,477 SH   DFND 1, 2 4,313,477 0 0
BRIGGS & STRATTON CORP COM 109043109 1,412 1,077,815 SH   DFND 1, 2 1,077,815 0 0
BRIGHT HORIZONS FAM SOL IN D COM 109194100 352,366 3,006,533 SH   DFND 1, 2 3,006,533 0 0
BRIGHTHOUSE FINL INC COM 10922N103 1,054 37,890 SH   DFND 1, 2 37,890 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 644,462 10,960,230 SH   DFND 1, 2 10,960,230 0 0
BRITISH AMERN TOB PLC SPONSORED ADR 110448107 168,620 4,343,409 SH   DFND 1, 2 4,315,856 0 27,553
BROADCOM INC COM 11135F101 12,319,867 39,035,422 SH   DFND 1, 2 39,017,754 0 17,668
BROOKFIELD ASSET MGMT INC CL A LTD VT SH 112585104 428,791 13,033,074 SH   DFND 1, 2 12,996,199 0 36,875
BROOKFIELD INFRASTRUCTURE CO COM SB VTG SHS A 11275Q107 6,497 142,590 SH   DFND 1, 2 142,590 0 0
BURLINGTON STORES INC COM 122017106 630,982 3,204,094 SH   DFND 1, 2 3,204,094 0 0
CDW CORP COM 12514G108 75,517 650,000 SH   DFND 1, 2 650,000 0 0
CF INDS HLDGS INC COM 125269100 163,809 5,821,212 SH   DFND 1, 2 5,821,212 0 0
CIGNA CORP NEW COM 125523100 3,050,881 16,258,361 SH   DFND 1, 2 16,249,463 0 8,898
CIT GROUP INC COM NEW 125581801 101,167 4,880,200 SH   DFND 1, 2 4,880,200 0 0
CME GROUP INC COM 12572Q105 5,647,907 34,747,815 SH   DFND 1, 2 34,741,554 0 6,261
CMS ENERGY CORP COM 125896100 903,206 15,461,082 SH   DFND 1, 2 15,426,059 0 35,023
CSX CORP COM 126408103 4,566,988 65,486,314 SH   DFND 1, 2 65,464,427 0 21,887
CVS HEALTH CORP COM 126650100 1,725,275 26,555,128 SH   DFND 1, 2 26,534,014 0 21,114
CABOT OIL & GAS CORP COM 127097103 185,522 10,798,700 SH   DFND 1, 2 10,798,700 0 0
CABOT MICROELECTRONICS CORP COM 12709P103 52,774 378,200 SH   DFND 1, 2 378,200 0 0
CAMDEN PPTY TR SH BEN INT 133131102 235,374 2,580,285 SH   DFND 1, 2 2,580,285 0 0
CANADIAN NAT RES LTD COM 136385101 127,537 7,352,180 SH   DFND 1, 2 7,345,947 0 6,233
CANNAE HLDGS INC COM 13765N107 59,286 1,442,473 SH   DFND 1, 2 1,442,473 0 0
CAPITAL ONE FINL CORP COM 14040H105 1,541,199 24,623,822 SH   DFND 1, 2 24,597,075 0 26,747
CARGURUS INC COM CL A 141788109 29,858 1,177,827 SH   DFND 1, 2 1,177,827 0 0
CARLYLE GROUP INC COM 14316J108 351,990 12,616,142 SH   DFND 1, 2 12,616,142 0 0
CARNIVAL CORP UNIT 99/99/9999 143658300 21,232 1,293,069 SH   DFND 1, 2 1,293,069 0 0
CARVANA CO CL A 146869102 27,617 229,755 SH   DFND 1, 2 229,755 0 0
CATERPILLAR INC DEL COM 149123101 191,735 1,515,796 SH   DFND 1, 2 1,505,124 0 10,672
CAVCO INDS INC DEL COM 149568107 32,952 170,870 SH   DFND 1, 2 170,870 0 0
CELLECTIS S A SPON ADS 15117K103 15,575 875,000 SH   DFND 1, 2 875,000 0 0
CENTENE CORP DEL COM 15135B101 2,554,916 40,203,241 SH   DFND 1, 2 40,203,241 0 0
CENOVUS ENERGY INC COM 15135U109 59,864 12,798,618 SH   DFND 1, 2 12,798,618 0 0
CENTURY CMNTYS INC COM 156504300 27,931 911,000 SH   DFND 1, 2 911,000 0 0
CERIDIAN HCM HLDG INC COM 15677J108 480,656 6,063,533 SH   DFND 1, 2 6,063,533 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 1,100,925 2,158,508 SH   DFND 1, 2 2,158,508 0 0
CHEMED CORP NEW COM 16359R103 125,942 279,207 SH   DFND 1, 2 279,207 0 0
CHEVRON CORP NEW COM 166764100 1,267,119 14,200,784 SH   DFND 1, 2 14,190,158 0 10,626
CHEWY INC CL A 16679L109 7,222 161,600 SH   DFND 1, 2 161,600 0 0
CHIPOTLE MEXICAN GRILL INC COM 169656105 302,744 287,681 SH   DFND 1, 2 287,681 0 0
CINTAS CORP COM 172908105 156,117 586,112 SH   DFND 1, 2 586,112 0 0
CITIGROUP INC COM NEW 172967424 1,300,558 25,451,234 SH   DFND 1, 2 25,451,234 0 0
CLEAR CHANNEL OUTDOOR HLDGS COM 18453H106 1,085 1,043,695 SH   DFND 1, 2 1,043,695 0 0
CLOUDFLARE INC CL A COM 18915M107 9,505 264,395 SH   DFND 1, 2 264,395 0 0
COCA COLA CO COM 191216100 1,279,009 28,626,117 SH   DFND 1, 2 28,607,600 0 18,517
COLGATE PALMOLIVE CO COM 194162103 1,649,728 22,518,810 SH   DFND 1, 2 22,518,810 0 0
COMCAST CORP NEW CL A 20030N101 3,863,041 99,103,234 SH   DFND 1, 2 99,033,406 0 69,828
CONAGRA BRANDS INC COM 205887102 1,990,584 56,598,909 SH   DFND 1, 2 56,598,909 0 0
CONCHO RES INC COM 20605P101 78,576 1,525,748 SH   DFND 1, 2 1,525,748 0 0
CONOCOPHILLIPS COM 20825C104 204,648 4,870,259 SH   DFND 1, 2 4,870,259 0 0
CONSTELLATION BRANDS INC CL A 21036P108 87,435 499,770 SH   DFND 1, 2 499,770 0 0
COOPER TIRE & RUBR CO COM 216831107 17,008 616,000 SH   DFND 1, 2 616,000 0 0
COPART INC COM 217204106 59,545 715,086 SH   DFND 1, 2 715,086 0 0
CORTEVA INC COM 22052L104 287,018 10,713,615 SH   DFND 1, 2 10,713,615 0 0
CORTEXYME INC COM 22053A107 120,627 2,605,334 SH   DFND 1, 2 2,605,334 0 0
COSTCO WHSL CORP NEW COM 22160K105 1,652,131 5,448,824 SH   DFND 1, 2 5,444,740 0 4,084
COSTAR GROUP INC COM 22160N109 35,534 50,000 SH   DFND 1, 2 50,000 0 0
COWEN INC CL A NEW 223622606 10,374 640,000 SH   DFND 1, 2 640,000 0 0
CROWN CASTLE INTL CORP NEW COM 22822V101 3,187,266 19,045,509 SH   DFND 1, 2 19,045,509 0 0
CROWN CASTLE INTL CORP NEW 6.875% CON PFD A 22822V309 451,876 304,234 SH   DFND 1, 2 304,234 0 0
CUMULUS MEDIA INC COM CLASS A 231082801 3,077 779,084 SH   DFND 1, 2 779,084 0 0
D R HORTON INC COM 23331A109 499,047 8,999,940 SH   DFND 1, 2 8,999,940 0 0
DTE ENERGY CO COM 233331107 2,365,563 22,005,241 SH   DFND 1, 2 22,005,241 0 0
DTE ENERGY CO UNIT 11/01/2022S 233331842 154,591 3,652,915 SH   DFND 1, 2 3,652,915 0 0
DANAHER CORPORATION COM 235851102 589,858 3,335,733 SH   DFND 1, 2 3,335,733 0 0
DANAHER CORPORATION 4.75 MND CV PFD 235851300 187,031 150,000 SH   DFND 1, 2 150,000 0 0
DARDEN RESTAURANTS INC COM 237194105 534,400 7,052,919 SH   DFND 1, 2 7,052,919 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 16,124 270,000 SH   DFND 1, 2 270,000 0 0
DEERE & CO COM 244199105 379,234 2,413,199 SH   DFND 1, 2 2,413,199 0 0
DELL TECHNOLOGIES INC CL C 24703L202 572,800 10,425,919 SH   DFND 1, 2 10,425,919 0 0
DELTA AIR LINES INC DEL COM NEW 247361702 357,676 12,751,359 SH   DFND 1, 2 12,751,359 0 0
DENBURY RES INC COM NEW 247916208 17 60,000 SH   DFND 1, 2 60,000 0 0
DEXCOM INC COM 252131107 722,332 1,781,775 SH   DFND 1, 2 1,781,775 0 0
DIAMONDBACK ENERGY INC COM 25278X109 59,837 1,430,832 SH   DFND 1, 2 1,430,832 0 0
DIEBOLD NXDF INC COM 253651103 6,284 1,037,000 SH   DFND 1, 2 1,037,000 0 0
DIGITAL RLTY TR INC COM 253868103 3,426,515 24,111,873 SH   DFND 1, 2 24,100,329 0 11,544
DISNEY WALT CO COM DISNEY 254687106 364,773 3,271,216 SH   DFND 1, 2 3,271,216 0 0
DISCOVER FINL SVCS COM 254709108 459,754 9,178,853 SH   DFND 1, 2 9,159,875 0 18,978
DISH NETWORK CORPORATION NOTE 3.375% 8/1 25470MAB5 35,767 38,830,000 PRN   DFND 1, 2 38,830,000 0 0
DOCUSIGN INC COM 256163106 444,961 2,583,829 SH   DFND 1, 2 2,583,829 0 0
DOLLAR GEN CORP NEW COM 256677105 2,081,141 10,924,050 SH   DFND 1, 2 10,924,050 0 0
DOMINION ENERGY INC COM 25746U109 162,897 2,006,618 SH   DFND 1, 2 2,006,618 0 0
DOMINION ENERGY INC UNIT 99/99/9999 25746U133 229,508 2,264,728 SH   DFND 1, 2 2,264,728 0 0
DOMINOS PIZZA INC COM 25754A201 1,300,580 3,520,409 SH   DFND 1, 2 3,520,409 0 0
DOW INC COM 260557103 1,715,828 42,095,821 SH   DFND 1, 2 42,085,530 0 10,291
DRAFTKINGS INC COM CL A 26142R104 111,221 3,344,000 SH   DFND 1, 2 3,344,000 0 0
DUKE ENERGY CORP NEW COM NEW 26441C204 240,469 3,010,000 SH   DFND 1, 2 3,010,000 0 0
DUPONT DE NEMOURS INC COM 26614N102 346,253 6,517,089 SH   DFND 1, 2 6,517,089 0 0
EOG RES INC COM 26875P101 223,466 4,411,084 SH   DFND 1, 2 4,411,084 0 0
EASTMAN CHEM CO COM 277432100 331,491 4,760,060 SH   DFND 1, 2 4,760,060 0 0
EDITAS MEDICINE INC COM 28106W103 52,061 1,760,000 SH   DFND 1, 2 1,760,000 0 0
ELDORADO RESORTS INC COM 28470R102 344,580 8,601,604 SH   DFND 1, 2 8,601,604 0 0
EMERSON ELEC CO COM 291011104 686,683 11,070,182 SH   DFND 1, 2 11,070,182 0 0
ENBRIDGE INC COM 29250N105 323,216 10,625,993 SH   DFND 1, 2 10,609,652 0 16,341
ENDAVA PLC ADS 29260V105 56,308 1,165,798 SH   DFND 1, 2 1,165,798 0 0
EPAM SYS INC COM 29414B104 754,485 2,993,870 SH   DFND 1, 2 2,993,870 0 0
EQUIFAX INC COM 294429105 26,035 151,473 SH   DFND 1, 2 151,473 0 0
EQUINIX INC COM 29444U700 1,767,784 2,517,135 SH   DFND 1, 2 2,517,135 0 0
ESSENTIAL UTILS INC UNIT 04/30/2022 29670G201 5,179 91,600 SH   DFND 1, 2 91,600 0 0
ETSY INC COM 29786A106 54,910 516,900 SH   DFND 1, 2 516,900 0 0
EXACT SCIENCES CORP COM 30063P105 77,377 890,000 SH   DFND 1, 2 890,000 0 0
EXELON CORP COM 30161N101 61,874 1,705,000 SH   DFND 1, 2 1,705,000 0 0
EXTRA SPACE STORAGE INC COM 30225T102 199,964 2,164,817 SH   DFND 1, 2 2,164,817 0 0
EXXON MOBIL CORP COM 30231G102 462,932 10,352,025 SH   DFND 1, 2 10,325,181 0 26,844
FLIR SYS INC COM 302445101 109,409 2,696,785 SH   DFND 1, 2 2,696,785 0 0
FACEBOOK INC CL A 30303M102 9,316,162 41,027,952 SH   DFND 1, 2 41,019,362 0 8,590
FIDELITY NATL INFORMATION SV COM 31620M106 34,207 255,103 SH   DFND 1, 2 255,103 0 0
FIFTH THIRD BANCORP COM 316773100 29,678 1,539,335 SH   DFND 1, 2 1,539,335 0 0
FIRST REP BK SAN FRANCISCO C COM 33616C100 535,572 5,053,043 SH   DFND 1, 2 5,053,043 0 0
FISERV INC COM 337738108 674,451 6,908,940 SH   DFND 1, 2 6,908,940 0 0
FIVE BELOW INC COM 33829M101 391,699 3,663,820 SH   DFND 1, 2 3,663,820 0 0
FLEETCOR TECHNOLOGIES INC COM 339041105 29,932 119,000 SH   DFND 1, 2 119,000 0 0
FLEXION THERAPEUTICS INC COM 33938J106 50,272 3,823,000 SH   DFND 1, 2 3,823,000 0 0
FLOOR & DECOR HLDGS INC CL A 339750101 623,591 10,816,839 SH   DFND 1, 2 10,816,839 0 0
FLUOR CORP NEW COM 343412102 8,516 705,000 SH   DFND 1, 2 705,000 0 0
FOCUS FINL PARTNERS INC COM CL A 34417P100 78,682 2,380,700 SH   DFND 1, 2 2,380,700 0 0
FRANCO NEV CORP COM 351858105 1,002,307 7,174,961 SH   DFND 1, 2 7,174,961 0 0
FRONTDOOR INC COM 35905A109 25,179 568,000 SH   DFND 1, 2 568,000 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 228,894 1,865,171 SH   DFND 1, 2 1,865,171 0 0
GALAPAGOS NV SPON ADR 36315X101 747 3,800 SH   DFND 1, 2 2 0 3,798
GAMING & LEISURE PPTYS INC COM 36467J108 596,838 17,249,656 SH   DFND 1, 2 17,249,656 0 0
GENERAL ELECTRIC CO COM 369604103 38,947 5,702,333 SH   DFND 1, 2 5,702,333 0 0
GENERAL MLS INC COM 370334104 970,995 15,750,122 SH   DFND 1, 2 15,750,122 0 0
GENERAL MTRS CO COM 37045V100 2,387,347 94,361,525 SH   DFND 1, 2 94,306,798 0 54,727
GENETRON HLDGS LTD ADS 37186H100 29,839 2,472,191 SH   DFND 1, 2 2,472,191 0 0
GENTEX CORP COM 371901109 82,674 3,208,134 SH   DFND 1, 2 3,208,134 0 0
GILEAD SCIENCES INC COM 375558103 3,347,143 43,503,830 SH   DFND 1, 2 43,486,283 0 17,547
GLAUKOS CORP COM 377322102 44,195 1,150,322 SH   DFND 1, 2 1,150,322 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 16,340 400,586 SH   DFND 1, 2 400,586 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 91,702 1,452,595 SH   DFND 1, 2 1,452,595 0 0
GODADDY INC CL A 380237107 10,413 142,000 SH   DFND 1, 2 142,000 0 0
GOGO INC NOTE 6.000% 5/1 38046CAD1 3,353 4,767,000 PRN   DFND 1, 2 4,767,000 0 0
GOLDMAN SACHS GROUP INC COM 38141G104 159,000 804,603 SH   DFND 1, 2 803,191 0 1,412
GOSSAMER BIO INC COM 38341P102 4,056 312,000 SH   DFND 1, 2 312,000 0 0
GRACE W R & CO DEL NEW COM 38388F108 17,682 348,000 SH   DFND 1, 2 348,000 0 0
GRACO INC COM 384109104 45,782 954,000 SH   DFND 1, 2 954,000 0 0
GRAND CANYON ED INC COM 38526M106 427,966 4,727,340 SH   DFND 1, 2 4,727,340 0 0
GREENHILL & CO INC COM 395259104 11,685 1,169,700 SH   DFND 1, 2 1,169,700 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 11,243 616,400 SH   DFND 1, 2 616,400 0 0
GROCERY OUTLET HLDG CORP COM 39874R101 48,634 1,192,000 SH   DFND 1, 2 1,192,000 0 0
GUIDEWIRE SOFTWARE INC COM 40171V100 399,362 3,602,721 SH   DFND 1, 2 3,602,721 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 35,023 770,209 SH   DFND 1, 2 710,701 0 59,508
HAEMONETICS CORP COM 405024100 55,536 620,100 SH   DFND 1, 2 620,100 0 0
HARLEY DAVIDSON INC COM 412822108 14,072 592,000 SH   DFND 1, 2 592,000 0 0
HEICO CORP NEW COM 422806109 136,275 1,367,535 SH   DFND 1, 2 1,367,535 0 0
HELMERICH & PAYNE INC COM 423452101 26,534 1,360,000 SH   DFND 1, 2 1,360,000 0 0
HENRY JACK & ASSOC INC COM 426281101 727,225 3,951,664 SH   DFND 1, 2 3,951,664 0 0
HESS CORP COM 42809H107 129,621 2,501,862 SH   DFND 1, 2 2,501,862 0 0
HOME DEPOT INC COM 437076102 8,068,660 32,209,222 SH   DFND 1, 2 32,192,810 0 16,412
HONEYWELL INTL INC COM 438516106 3,888,332 26,892,289 SH   DFND 1, 2 26,874,135 0 18,154
HUBBELL INC COM 443510607 323,429 2,580,000 SH   DFND 1, 2 2,580,000 0 0
HUBSPOT INC COM 443573100 288,781 1,287,190 SH   DFND 1, 2 1,287,190 0 0
HUMANA INC COM 444859102 1,872,699 4,829,722 SH   DFND 1, 2 4,826,655 0 3,067
HUNTSMAN CORP COM 447011107 77,505 4,313,000 SH   DFND 1, 2 4,313,000 0 0
HUYA INC ADS REP SHS A 44852D108 145,175 7,775,851 SH   DFND 1, 2 7,775,851 0 0
ICICI BANK LIMITED ADR 45104G104 1,044 114,429 SH   DFND 1, 2 1,598 0 112,831
IDEX CORP COM 45167R104 399,840 2,530,073 SH   DFND 1, 2 2,526,552 0 3,521
IDEXX LABS INC COM 45168D104 360,326 1,091,368 SH   DFND 1, 2 1,091,368 0 0
IHEARTMEDIA INC COM CL A 45174J509 3,893 466,239 SH   DFND 1, 2 466,239 0 0
ILLINOIS TOOL WKS INC COM 452308109 522,845 2,990,246 SH   DFND 1, 2 2,990,246 0 0
ILLUMINA INC COM 452327109 966,975 2,610,977 SH   DFND 1, 2 2,610,977 0 0
INCYTE CORP COM 45337C102 56,954 547,796 SH   DFND 1, 2 547,796 0 0
INPHI CORP COM 45772F107 160,701 1,367,665 SH   DFND 1, 2 1,367,665 0 0
INSULET CORP COM 45784P101 1,240,836 6,387,587 SH   DFND 1, 2 6,385,340 0 2,247
INTEL CORP COM 458140100 1,246,484 20,834,544 SH   DFND 1, 2 20,804,617 0 29,927
INTERCEPT PHARMACEUTICALS IN COM 45845P108 10,211 213,137 SH   DFND 1, 2 213,137 0 0
INTERCONTINENTAL HOTELS GROU SPONSORED ADS 45857P806 299 6,623 SH   DFND 1, 2 9 0 6,614
INTERCONTINENTAL EXCHANGE IN COM 45866F104 1,653,130 18,047,368 SH   DFND 1, 2 18,039,992 0 7,376
INTERNATIONAL BUSINESS MACHS COM 459200101 538,247 4,456,791 SH   DFND 1, 2 4,456,791 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 2,791,670 4,899,188 SH   DFND 1, 2 4,897,042 0 2,146
IRIDIUM COMMUNICATIONS INC COM 46269C102 98,551 3,873,868 SH   DFND 1, 2 3,873,868 0 0
IRON MTN INC NEW COM 46284V101 919,775 35,240,410 SH   DFND 1, 2 35,240,410 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 20,950 2,030,000 SH   DFND 1, 2 2,030,000 0 0
JOYY INC ADS REPSTG COM A 46591M109 271,123 3,061,812 SH   DFND 1, 2 3,061,812 0 0
JPMORGAN CHASE & CO COM 46625H100 6,851,835 72,845,777 SH   DFND 1, 2 72,809,326 0 36,451
JACOBS ENGR GROUP INC COM 469814107 217,752 2,567,835 SH   DFND 1, 2 2,567,835 0 0
JELD-WEN HLDG INC COM 47580P103 6,686 415,000 SH   DFND 1, 2 415,000 0 0
JOHNSON & JOHNSON COM 478160104 3,250,357 23,112,974 SH   DFND 1, 2 23,099,827 0 13,147
KB HOME COM 48666K109 90,749 2,957,918 SH   DFND 1, 2 2,957,918 0 0
KELLOGG CO COM 487836108 1,026,873 15,544,552 SH   DFND 1, 2 15,544,552 0 0
KEURIG DR PEPPER INC COM 49271V100 1,283,760 45,202,807 SH   DFND 1, 2 45,202,807 0 0
KEYCORP COM 493267108 510,298 41,896,396 SH   DFND 1, 2 41,896,396 0 0
KINSALE CAP GROUP INC COM 49714P108 13,506 87,020 SH   DFND 1, 2 87,020 0 0
KONINKLIJKE PHILIPS N V NY REG SH NEW 500472303 953 20,383 SH   DFND 1, 2 12 0 20,371
KONTOOR BRANDS INC COM 50050N103 100,114 5,621,240 SH   DFND 1, 2 5,621,240 0 0
L3HARRIS TECHNOLOGIES INC COM 502431109 629,003 3,707,212 SH   DFND 1, 2 3,707,212 0 0
LAM RESEARCH CORP COM 512807108 69,198 213,932 SH   DFND 1, 2 213,932 0 0
LAMAR ADVERTISING CO NEW CL A 512816109 157,108 2,353,322 SH   DFND 1, 2 2,353,322 0 0
LAS VEGAS SANDS CORP COM 517834107 279,107 6,128,828 SH   DFND 1, 2 6,128,828 0 0
LAUDER ESTEE COS INC CL A 518439104 294,703 1,561,922 SH   DFND 1, 2 1,561,922 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 27,664 650,000 SH   DFND 1, 2 650,000 0 0
LENNAR CORP CL A 526057104 226,519 3,676,070 SH   DFND 1, 2 3,676,070 0 0
LENNAR CORP CL B 526057302 976 21,169 SH   DFND 1, 2 21,169 0 0
LENNOX INTL INC COM 526107107 280,994 1,206,034 SH   DFND 1, 2 1,206,034 0 0
LILLY ELI & CO COM 532457108 505,334 3,077,924 SH   DFND 1, 2 3,077,924 0 0
LIVE NATION ENTERTAINMENT IN COM 538034109 69,346 1,564,311 SH   DFND 1, 2 1,564,311 0 0
LIVE NATION ENTERTAINMENT IN NOTE 2.500% 3/1 538034AQ2 6,081 5,980,000 PRN   DFND 1, 2 5,980,000 0 0
LOCKHEED MARTIN CORP COM 539830109 6,056,100 16,595,630 SH   DFND 1, 2 16,586,686 0 8,944
LULULEMON ATHLETICA INC COM 550021109 42,129 135,023 SH   DFND 1, 2 135,023 0 0
M D C HLDGS INC COM 552676108 34,541 967,528 SH   DFND 1, 2 967,528 0 0
MGM GROWTH PPTYS LLC CL A COM 55303A105 90,809 3,337,327 SH   DFND 1, 2 3,337,327 0 0
MACYS INC COM 55616P104 13,072 1,900,000 SH   DFND 1, 2 1,900,000 0 0
MAGNOLIA OIL & GAS CORP CL A 559663109 12,120 2,000,000 SH   DFND 1, 2 2,000,000 0 0
MANULIFE FINL CORP COM 56501R106 841 61,805 SH   DFND 1, 2 61,805 0 0
MARKETAXESS HLDGS INC COM 57060D108 222,657 444,496 SH   DFND 1, 2 444,496 0 0
MARSH & MCLENNAN COS INC COM 571748102 1,779,323 16,572,254 SH   DFND 1, 2 16,553,162 0 19,092
MARRIOTT INTL INC NEW CL A 571903202 513,891 5,994,293 SH   DFND 1, 2 5,994,293 0 0
MASCO CORP COM 574599106 117,843 2,347,000 SH   DFND 1, 2 2,347,000 0 0
MASTERCARD INCORPORATED CL A 57636Q104 4,212,276 14,245,147 SH   DFND 1, 2 14,240,136 0 5,011
MAXIM INTEGRATED PRODS INC COM 57772K101 58,186 960,000 SH   DFND 1, 2 960,000 0 0
MELCO RESORTS AND ENTMNT LTD ADR 585464100 306,266 19,733,779 SH   DFND 1, 2 19,714,511 0 19,268
MERCADOLIBRE INC COM 58733R102 2,421,965 2,456,939 SH   DFND 1, 2 2,454,553 0 2,386
MERCK & CO. INC COM 58933Y105 2,587,990 33,467,152 SH   DFND 1, 2 33,446,390 0 20,762
METLIFE INC COM 59156R108 16,308 446,557 SH   DFND 1, 2 446,557 0 0
METTLER TOLEDO INTERNATIONAL COM 592688105 317,342 393,945 SH   DFND 1, 2 393,945 0 0
MICROSOFT CORP COM 594918104 25,015,917 122,923,512 SH   DFND 1, 2 122,874,895 0 48,617
MOELIS & CO CL A 60786M105 22,404 719,000 SH   DFND 1, 2 719,000 0 0
MOLINA HEALTHCARE INC COM 60855R100 1,029,801 5,786,048 SH   DFND 1, 2 5,786,048 0 0
MONDELEZ INTL INC CL A 609207105 1,278,718 25,009,150 SH   DFND 1, 2 25,009,150 0 0
MONEYGRAM INTL INC COM NEW 60935Y208 8,484 2,642,886 SH   DFND 1, 2 2,642,886 0 0
MONGODB INC CL A 60937P106 1,587,490 7,013,740 SH   DFND 1, 2 7,013,740 0 0
MOODYS CORP COM 615369105 505,860 1,841,327 SH   DFND 1, 2 1,839,878 0 1,449
MORGAN STANLEY COM NEW 617446448 303,201 6,277,460 SH   DFND 1, 2 6,277,460 0 0
MOTOROLA SOLUTIONS INC COM NEW 620076307 762,171 5,439,025 SH   DFND 1, 2 5,439,025 0 0
NMI HLDGS INC CL A 629209305 8,136 506,000 SH   DFND 1, 2 506,000 0 0
NVR INC COM 62944T105 338,825 103,974 SH   DFND 1, 2 103,974 0 0
NASDAQ INC COM 631103108 1,096,409 9,177,273 SH   DFND 1, 2 9,177,273 0 0
NATERA INC COM 632307104 101,016 2,026,000 SH   DFND 1, 2 2,026,000 0 0
NAVIENT CORPORATION COM 63938C108 5,273 750,000 SH   DFND 1, 2 750,000 0 0
NEOVASC INC COM 64065J304 2,166 910,000 SH   DFND 1, 2 910,000 0 0
NETFLIX INC COM 64110L106 6,223,193 13,676,170 SH   DFND 1, 2 13,674,749 0 1,421
NEVRO CORP COM 64157F103 19,115 160,000 SH   DFND 1, 2 160,000 0 0
NEW FORTRESS ENERGY LLC CL A SHS RP LLC 644393100 30,640 2,364,221 SH   DFND 1, 2 2,364,221 0 0
NEW YORK TIMES CO CL A 650111107 269,626 6,415,094 SH   DFND 1, 2 6,415,094 0 0
NEXSTAR MEDIA GROUP INC CL A 65336K103 88,801 1,061,069 SH   DFND 1, 2 1,061,069 0 0
NEXTERA ENERGY INC UNIT 99/99/9999 65339F770 145,192 3,420,300 SH   DFND 1, 2 3,420,300 0 0
NIKE INC CL B 654106103 1,854,672 18,915,721 SH   DFND 1, 2 18,909,290 0 6,431
NINE ENERGY SERVICE INC COM 65441V101 2,340 1,200,000 SH   DFND 1, 2 1,200,000 0 0
NOBLE ENERGY INC COM 655044105 19,936 2,225,000 SH   DFND 1, 2 2,225,000 0 0
NORDSTROM INC COM 655664100 77,478 5,001,800 SH   DFND 1, 2 5,001,800 0 0
NORFOLK SOUTHERN CORP COM 655844108 1,150,970 6,555,667 SH   DFND 1, 2 6,552,741 0 2,926
NORTHROP GRUMMAN CORP COM 666807102 2,086,110 6,785,395 SH   DFND 1, 2 6,780,222 0 5,173
NORTONLIFELOCK INC COM 668771108 1,458,373 73,543,791 SH   DFND 1, 2 73,543,791 0 0
NOVARTIS AG SPONSORED ADR 66987V109 78,932 903,739 SH   DFND 1, 2 887,434 0 16,305
NOVAVAX INC COM NEW 670002401 37,026 444,228 SH   DFND 1, 2 444,228 0 0
NOVO-NORDISK A S ADR 670100205 1,236 18,857 SH   DFND 1, 2 11 0 18,846
NUCOR CORP COM 670346105 681,796 16,464,521 SH   DFND 1, 2 16,464,521 0 0
NUVASIVE INC COM 670704105 42,636 766,000 SH   DFND 1, 2 766,000 0 0
NUTRIEN LTD COM 67077M108 421 13,092 SH   DFND 1, 2 13,092 0 0
OCCIDENTAL PETE CORP COM 674599105 196,673 10,747,154 SH   DFND 1, 2 10,747,154 0 0
OKTA INC CL A 679295105 100,115 500,000 SH   DFND 1, 2 500,000 0 0
OSHKOSH CORP COM 688239201 54,446 760,207 SH   DFND 1, 2 760,207 0 0
PGT INNOVATIONS INC COM 69336V101 34,213 2,181,973 SH   DFND 1, 2 2,181,973 0 0
PNC FINL SVCS GROUP INC COM 693475105 1,662,556 15,802,734 SH   DFND 1, 2 15,781,963 0 20,771
PPD INC COM 69355F102 21,072 786,282 SH   DFND 1, 2 786,282 0 0
PACCAR INC COM 693718108 1,283,119 17,142,532 SH   DFND 1, 2 17,142,532 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 18,789 5,446,000 SH   DFND 1, 2 5,446,000 0 0
PACKAGING CORP AMER COM 695156109 590,369 5,915,525 SH   DFND 1, 2 5,915,525 0 0
PARKER HANNIFIN CORP COM 701094104 753,210 4,109,839 SH   DFND 1, 2 4,109,839 0 0
PAYCHEX INC COM 704326107 125,518 1,657,000 SH   DFND 1, 2 1,657,000 0 0
PAYCOM SOFTWARE INC COM 70432V102 339,904 1,097,419 SH   DFND 1, 2 1,097,419 0 0
PAYLOCITY HLDG CORP COM 70438V106 21,884 150,000 SH   DFND 1, 2 150,000 0 0
PAYPAL HLDGS INC COM 70450Y103 3,622,960 20,794,311 SH   DFND 1, 2 20,788,666 0 5,645
PELOTON INTERACTIVE INC CL A COM 70614W100 347,050 6,007,443 SH   DFND 1, 2 6,007,443 0 0
PEMBINA PIPELINE CORP COM 706327103 546 21,827 SH   DFND 1, 2 21,827 0 0
PENN NATL GAMING INC NOTE 2.750% 5/1 707569AU3 6,523 4,340,000 PRN   DFND 1, 2 4,340,000 0 0
PENUMBRA INC COM 70975L107 131,607 735,974 SH   DFND 1, 2 735,974 0 0
PETROLEO BRASILEIRO SA PETRO SP ADR NON VTG 71654V101 203,787 25,569,254 SH   DFND 1, 2 25,569,254 0 0
PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408 525,536 63,547,244 SH   DFND 1, 2 63,487,081 0 60,163
PFIZER INC COM 717081103 7,993,133 244,438,509 SH   DFND 1, 2 244,339,959 0 98,550
PHILIP MORRIS INTL INC COM 718172109 5,849,969 83,499,413 SH   DFND 1, 2 83,499,413 0 0
PIONEER NAT RES CO COM 723787107 311,209 3,185,355 SH   DFND 1, 2 3,185,355 0 0
POLARIS INC COM 731068102 54,697 591,000 SH   DFND 1, 2 591,000 0 0
POOL CORPORATION COM 73278L105 111,385 409,700 SH   DFND 1, 2 409,700 0 0
PRECISION BIOSCIENCES INC COM 74019P108 33,836 4,062,000 SH   DFND 1, 2 4,062,000 0 0
PROCTER AND GAMBLE CO COM 742718109 1,076,825 9,005,810 SH   DFND 1, 2 9,005,810 0 0
PROGRESSIVE CORP OHIO COM 743315103 643,367 8,031,045 SH   DFND 1, 2 8,031,045 0 0
PROLOGIS INC. COM 74340W103 433,985 4,650,000 SH   DFND 1, 2 4,650,000 0 0
PUBLIC SVC ENTERPRISE GRP IN COM 744573106 706,249 14,366,326 SH   DFND 1, 2 14,366,326 0 0
PUBLIC STORAGE COM 74460D109 310,574 1,618,500 SH   DFND 1, 2 1,618,500 0 0
QUALCOMM INC COM 747525103 1,190,807 13,055,668 SH   DFND 1, 2 13,055,668 0 0
RH COM 74967X103 26,881 108,000 SH   DFND 1, 2 108,000 0 0
RADIAN GROUP INC COM 750236101 3,800 245,000 SH   DFND 1, 2 245,000 0 0
RATTLER MIDSTREAM LP COM UNITS 75419T103 7,499 773,144 SH   DFND 1, 2 773,144 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 450,555 7,311,838 SH   DFND 1, 2 7,311,838 0 0
REDWOOD TR INC COM 758075402 17,934 2,562,000 SH   DFND 1, 2 2,562,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107 4,325,216 6,935,355 SH   DFND 1, 2 6,933,924 0 1,431
REGIONS FINANCIAL CORP NEW COM 7591EP100 432,630 38,905,601 SH   DFND 1, 2 38,905,601 0 0
REPAY HLDGS CORP COM CL A 76029L100 50,024 2,031,034 SH   DFND 1, 2 2,031,034 0 0
REPUBLIC SVCS INC COM 760759100 114,987 1,401,421 SH   DFND 1, 2 1,401,421 0 0
RESMED INC COM 761152107 1,024,778 5,337,384 SH   DFND 1, 2 5,337,384 0 0
RESTAURANT BRANDS INTL INC COM 76131D103 1,010,176 18,503,543 SH   DFND 1, 2 18,494,271 0 9,272
REVANCE THERAPEUTICS INC COM 761330109 52,015 2,130,000 SH   DFND 1, 2 2,130,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 29,059 920,453 SH   DFND 1, 2 920,453 0 0
REXNORD CORP COM 76169B102 140,736 4,828,000 SH   DFND 1, 2 4,828,000 0 0
RINGCENTRAL INC CL A 76680R206 3,068,322 10,765,666 SH   DFND 1, 2 10,765,666 0 0
RIO TINTO PLC SPONSORED ADR 767204100 754 13,557 SH   DFND 1, 2 8 0 13,549
ROYAL DUTCH SHELL PLC SPON ADR B 780259107 197,719 6,492,489 SH   DFND 1, 2 6,467,511 0 24,978
ROYAL GOLD INC COM 780287108 885,564 7,123,259 SH   DFND 1, 2 7,123,259 0 0
RUBIUS THERAPEUTICS INC COM 78116T103 6,680 1,117,000 SH   DFND 1, 2 1,117,000 0 0
S&P GLOBAL INC COM 78409V104 1,271,844 3,860,154 SH   DFND 1, 2 3,860,154 0 0
SVB FINANCIAL GROUP COM 78486Q101 211,458 981,108 SH   DFND 1, 2 981,108 0 0
SAIA INC COM 78709Y105 76,714 690,000 SH   DFND 1, 2 690,000 0 0
SAILPOINT TECHNLGIES HLDGS I COM 78781P105 17,577 664,029 SH   DFND 1, 2 664,029 0 0
SAP SE SPON ADR 803054204 1,423 10,278 SH   DFND 1, 2 6 0 10,272
SEA LTD SPONSORED ADS 81141R100 2,455,011 22,892,257 SH   DFND 1, 2 22,862,872 0 29,385
SEACOAST BKG CORP FLA COM NEW 811707801 73,071 3,581,901 SH   DFND 1, 2 3,581,901 0 0
SEATTLE GENETICS INC COM 812578102 49,717 292,591 SH   DFND 1, 2 292,591 0 0
SEMPRA ENERGY COM 816851109 21,292 181,622 SH   DFND 1, 2 181,622 0 0
SERVICEMASTER GLOBAL HLDGS I COM 81761R109 23,912 670,000 SH   DFND 1, 2 670,000 0 0
SERVICENOW INC COM 81762P102 1,182,061 2,918,276 SH   DFND 1, 2 2,916,751 0 1,525
SHAW COMMUNICATIONS INC CL B CONV 82028K200 124,223 7,617,209 SH   DFND 1, 2 7,617,209 0 0
SHERWIN WILLIAMS CO COM 824348106 1,901,969 3,291,472 SH   DFND 1, 2 3,290,756 0 716
SHOCKWAVE MED INC COM 82489T104 27,711 585,000 SH   DFND 1, 2 585,000 0 0
SHOPIFY INC CL A 82509L107 5,628,167 5,929,452 SH   DFND 1, 2 5,925,438 0 4,014
SILK RD MED INC COM 82710M100 90,758 2,166,580 SH   DFND 1, 2 2,166,580 0 0
SIMON PPTY GROUP INC NEW COM 828806109 903,648 13,215,098 SH   DFND 1, 2 13,215,098 0 0
SIMPLY GOOD FOODS CO COM 82900L102 91,990 4,951,000 SH   DFND 1, 2 4,951,000 0 0
SIX FLAGS ENTMT CORP NEW COM 83001A102 29,084 1,514,000 SH   DFND 1, 2 1,514,000 0 0
SMARTSHEET INC COM CL A 83200N103 724,928 14,236,688 SH   DFND 1, 2 14,232,637 0 4,051
SNAP INC CL A 83304A106 934,056 39,763,986 SH   DFND 1, 2 39,763,986 0 0
SOLARIS OILFIELD INFRSTR INC COM CL A 83418M103 6,617 891,761 SH   DFND 1, 2 891,761 0 0
SOUTH ST CORP COM 840441109 22,437 470,765 SH   DFND 1, 2 470,765 0 0
SOUTHWEST AIRLS CO NOTE 1.250% 5/0 844741BG2 6,874 5,700,000 PRN   DFND 1, 2 5,700,000 0 0
SOUTHWESTERN ENERGY CO COM 845467109 588 229,524 SH   DFND 1, 2 229,524 0 0
SQUARE INC CL A 852234103 1,028,844 9,804,120 SH   DFND 1, 2 9,804,120 0 0
STARBUCKS CORP COM 855244109 55,699 756,879 SH   DFND 1, 2 756,879 0 0
STERICYCLE INC COM 858912108 24,071 430,000 SH   DFND 1, 2 430,000 0 0
STRATEGIC ED INC COM 86272C103 179,421 1,167,725 SH   DFND 1, 2 1,167,725 0 0
SUN CMNTYS INC COM 866674104 661,959 4,878,823 SH   DFND 1, 2 4,878,823 0 0
SUNCOR ENERGY INC NEW COM 867224107 160,585 9,524,276 SH   DFND 1, 2 9,524,276 0 0
SYNCHRONY FINANCIAL COM 87165B103 953,359 43,021,626 SH   DFND 1, 2 43,021,626 0 0
TJX COS INC NEW COM 872540109 91,123 1,802,282 SH   DFND 1, 2 1,802,282 0 0
T-MOBILE US INC COM 872590104 2,520,586 24,201,500 SH   DFND 1, 2 24,201,500 0 0
T-MOBILE US INC RIGHT 07/27/2020 872590112 3,559 21,182,849 SH   DFND 1, 2 21,182,849 0 0
TTM TECHNOLOGIES INC COM 87305R109 13,841 1,167,000 SH   DFND 1, 2 1,167,000 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 2,303,186 40,571,116 SH   DFND 1, 2 40,476,291 0 94,825
TANDEM DIABETES CARE INC COM NEW 875372203 80,966 818,502 SH   DFND 1, 2 818,502 0 0
TARGET CORP COM 87612E106 1,257,412 10,484,549 SH   DFND 1, 2 10,484,549 0 0
TC ENERGY CORP COM 87807B107 215,637 5,047,835 SH   DFND 1, 2 5,019,766 0 28,069
TELADOC HEALTH INC COM 87918A105 479,850 2,514,411 SH   DFND 1, 2 2,514,411 0 0
TELUS CORPORATION COM 87971M103 58,173 3,468,408 SH   DFND 1, 2 3,468,408 0 0
10X GENOMICS INC CL A COM 88025U109 113,936 1,275,738 SH   DFND 1, 2 1,275,738 0 0
TESLA INC COM 88160R101 11,530,116 10,678,093 SH   DFND 1, 2 10,675,317 0 2,776
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 535,503 43,431,227 SH   DFND 1, 2 43,401,195 0 30,032
TEXAS INSTRS INC COM 882508104 1,501,272 11,824,079 SH   DFND 1, 2 11,809,741 0 14,338
TEXTRON INC COM 883203101 25,670 780,000 SH   DFND 1, 2 780,000 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 6,004,472 16,571,467 SH   DFND 1, 2 16,568,563 0 2,904
TOLL BROTHERS INC COM 889478103 423,279 12,988,009 SH   DFND 1, 2 12,988,009 0 0
TOPBUILD CORP COM 89055F103 151,064 1,327,800 SH   DFND 1, 2 1,327,800 0 0
TORONTO DOMINION BK ONT COM NEW 891160509 807,976 18,104,115 SH   DFND 1, 2 18,076,596 0 27,519
TRADEWEB MKTS INC CL A 892672106 246,821 4,245,285 SH   DFND 1, 2 4,245,285 0 0
TRANSDIGM GROUP INC COM 893641100 897,410 2,030,110 SH   DFND 1, 2 2,030,110 0 0
TRUPANION INC COM 898202106 119,340 2,795,507 SH   DFND 1, 2 2,795,507 0 0
TRUIST FINL CORP COM 89832Q109 491,994 13,102,364 SH   DFND 1, 2 13,102,364 0 0
TURQUOISE HILL RES LTD COM 900435108 21,133 28,792,379 SH   DFND 1, 2 28,792,379 0 0
TWIST BIOSCIENCE CORP COM 90184D100 31,891 704,000 SH   DFND 1, 2 704,000 0 0
TYLER TECHNOLOGIES INC COM 902252105 348,627 1,005,037 SH   DFND 1, 2 1,005,037 0 0
UBER TECHNOLOGIES INC COM 90353T100 288,833 9,293,222 SH   DFND 1, 2 9,293,222 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 253,230 3,237,413 SH   DFND 1, 2 3,237,413 0 0
UMPQUA HLDGS CORP COM 904214103 18,998 1,785,500 SH   DFND 1, 2 1,785,500 0 0
UNILEVER PLC SPON ADR NEW 904767704 87,857 1,600,900 SH   DFND 1, 2 1,600,900 0 0
UNILEVER N V N Y SHS NEW 904784709 37,202 698,374 SH   DFND 1, 2 698,374 0 0
UNION PAC CORP COM 907818108 1,394,151 8,246,057 SH   DFND 1, 2 8,243,404 0 2,653
UNITED PARCEL SERVICE INC CL B 911312106 687,155 6,180,562 SH   DFND 1, 2 6,180,562 0 0
UNITED RENTALS INC COM 911363109 28,352 190,234 SH   DFND 1, 2 190,234 0 0
UNITEDHEALTH GROUP INC COM 91324P102 11,763,764 39,884,157 SH   DFND 1, 2 39,871,088 0 13,069
UNITY BIOTECHNOLOGY INC COM 91381U101 15,928 1,835,000 SH   DFND 1, 2 1,835,000 0 0
V F CORP COM 918204108 575,848 9,449,550 SH   DFND 1, 2 9,435,927 0 13,623
VAIL RESORTS INC COM 91879Q109 31,330 172,000 SH   DFND 1, 2 172,000 0 0
VALE S A SPONSORED ADS 91912E105 469,361 45,525,770 SH   DFND 1, 2 45,426,627 0 99,143
VALERO ENERGY CORP COM 91913Y100 261,170 4,440,153 SH   DFND 1, 2 4,440,153 0 0
VEECO INSTRS INC DEL COM 922417100 20,100 1,490,000 SH   DFND 1, 2 1,490,000 0 0
VERISIGN INC COM 92343E102 111,742 540,258 SH   DFND 1, 2 540,258 0 0
VERIZON COMMUNICATIONS INC COM 92343V104 3,391,265 61,514,201 SH   DFND 1, 2 61,484,024 0 30,177
VERTEX PHARMACEUTICALS INC COM 92532F100 3,625,455 12,488,243 SH   DFND 1, 2 12,486,823 0 1,420
VERTIV HOLDINGS CO COM CL A 92537N108 7,262 551,851 SH   DFND 1, 2 551,851 0 0
VIAVI SOLUTIONS INC COM 925550105 73,026 5,732,000 SH   DFND 1, 2 5,732,000 0 0
VIACOMCBS INC CL B 92556H206 120,859 5,182,640 SH   DFND 1, 2 5,182,640 0 0
VICTORY CAP HLDGS INC COM CL A 92645B103 4,339 252,392 SH   DFND 1, 2 252,392 0 0
VISA INC COM CL A 92826C839 3,090,810 16,000,550 SH   DFND 1, 2 15,991,447 0 9,103
VISTRA ENERGY CORP COM 92840M102 6,879 369,425 SH   DFND 1, 2 369,425 0 0
VMWARE INC CL A COM 928563402 427,919 2,763,264 SH   DFND 1, 2 2,763,264 0 0
VULCAN MATLS CO COM 929160109 754,789 6,515,226 SH   DFND 1, 2 6,515,226 0 0
VROOM INC COM 92918V109 19,553 375,000 SH   DFND 1, 2 375,000 0 0
WADDELL & REED FINL INC CL A 930059100 28,694 1,850,000 SH   DFND 1, 2 1,850,000 0 0
WALMART INC COM 931142103 284,256 2,373,148 SH   DFND 1, 2 2,373,148 0 0
WALGREENS BOOTS ALLIANCE INC COM 931427108 179,091 4,224,832 SH   DFND 1, 2 4,224,832 0 0
WARNER MUSIC GROUP CORP COM CL A 934550203 64,995 2,203,205 SH   DFND 1, 2 2,203,205 0 0
WASTE CONNECTIONS INC COM 94106B101 78,784 840,000 SH   DFND 1, 2 840,000 0 0
WASTE MGMT INC DEL COM 94106L109 287,995 2,719,239 SH   DFND 1, 2 2,719,239 0 0
WATSCO INC COM 942622200 183,194 1,030,915 SH   DFND 1, 2 1,030,915 0 0
WAYFAIR INC CL A 94419L101 142,899 723,136 SH   DFND 1, 2 723,136 0 0
WESTLAKE CHEM CORP COM 960413102 164,718 3,070,228 SH   DFND 1, 2 3,070,228 0 0
WESTROCK CO COM 96145D105 113,040 4,000,000 SH   DFND 1, 2 4,000,000 0 0
WHEATON PRECIOUS METALS CORP COM 962879102 591,349 13,424,491 SH   DFND 1, 2 13,424,491 0 0
WINNEBAGO INDS INC COM 974637100 18,375 275,820 SH   DFND 1, 2 275,820 0 0
WORKDAY INC CL A 98138H101 244,753 1,306,327 SH   DFND 1, 2 1,306,327 0 0
WORLD WRESTLING ENTMT INC CL A 98156Q108 29,198 672,000 SH   DFND 1, 2 672,000 0 0
WYNN RESORTS LTD COM 983134107 227,919 3,059,720 SH   DFND 1, 2 3,059,720 0 0
XCEL ENERGY INC COM 98389B100 1,261,374 20,182,005 SH   DFND 1, 2 20,158,021 0 23,984
XENON PHARMACEUTICALS INC COM 98420N105 12,082 963,500 SH   DFND 1, 2 963,500 0 0
YELP INC CL A 985817105 13,531 585,000 SH   DFND 1, 2 585,000 0 0
YEXT INC COM 98585N106 158,117 9,519,378 SH   DFND 1, 2 9,519,378 0 0
YETI HLDGS INC COM 98585X104 37,004 866,000 SH   DFND 1, 2 866,000 0 0
ZAI LAB LTD ADR 98887Q104 486,483 5,923,328 SH   DFND 1, 2 5,923,328 0 0
ZENDESK INC COM 98936J101 433,259 4,893,927 SH   DFND 1, 2 4,893,927 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 21,609 450,000 SH   DFND 1, 2 450,000 0 0
ZILLOW GROUP INC CL A 98954M101 77,028 1,340,077 SH   DFND 1, 2 1,340,077 0 0
ZILLOW GROUP INC CL C CAP STK 98954M200 170,819 2,965,088 SH   DFND 1, 2 2,965,088 0 0
ZOETIS INC CL A 98978V103 1,297,239 9,466,322 SH   DFND 1, 2 9,461,294 0 5,028
ZOOMINFO TECHNOLOGIES INC COM CL A 98980F104 218,689 4,285,506 SH   DFND 1, 2 4,285,506 0 0
EURONAV NV ANTWERPEN SHS B38564108 6,113 750,000 SH   DFND 1, 2 750,000 0 0
AON PLC SHS CL A G0403H108 1,352,483 7,022,238 SH   DFND 1, 2 7,022,238 0 0
ARCH CAP GROUP LTD ORD G0450A105 543,008 18,953,169 SH   DFND 1, 2 18,953,169 0 0
ARCO PLATFORM LTD COM CL A G04553106 67,938 1,562,501 SH   DFND 1, 2 1,562,501 0 0
ATLASSIAN CORP PLC CL A G06242104 2,344 13,000 SH   DFND 1, 2 13,000 0 0
BANK OF NT BUTTERFIELD&SON L SHS NEW G0772R208 45,122 1,850,000 SH   DFND 1, 2 1,850,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 160,739 2,198,591 SH   DFND 1, 2 2,198,591 0 0
ACCENTURE PLC IRELAND SHS CLASS A G1151C101 98,340 457,992 SH   DFND 1, 2 457,992 0 0
BROOKFIELD PROPERTY PARTRS L UNIT LTD PARTN G16249107 23,421 2,368,154 SH   DFND 1, 2 2,368,154 0 0
BROOKFIELD INFRAST PARTNERS LP INT UNIT G16252101 759,952 18,466,283 SH   DFND 1, 2 18,466,283 0 0
CARDTRONICS PLC SHS CL A G1991C105 38,416 1,602,000 SH   DFND 1, 2 1,602,000 0 0
CLARIVATE PLC ORD SHS G21810109 74,834 3,351,279 SH   DFND 1, 2 3,351,279 0 0
CREDICORP LTD COM G2519Y108 27,675 207,037 SH   DFND 1, 2 207,037 0 0
COCA COLA EUROPEAN PARTNERS SHS G25839104 205,071 5,430,898 SH   DFND 1, 2 5,430,898 0 0
ENSTAR GROUP LIMITED SHS G3075P101 79,364 519,500 SH   DFND 1, 2 519,500 0 0
FRESH DEL MONTE PRODUCE INC ORD G36738105 25,309 1,028,000 SH   DFND 1, 2 1,028,000 0 0
JANUS HENDERSON GROUP PLC ORD SHS G4474Y214 25,393 1,200,041 SH   DFND 1, 2 1,200,041 0 0
JOHNSON CTLS INTL PLC SHS G51502105 49,147 1,439,710 SH   DFND 1, 2 1,426,064 0 13,646
LINDE PLC SHS G5494J103 2,732,303 12,887,828 SH   DFND 1, 2 12,875,219 0 12,609
NOMAD FOODS LTD USD ORD SHS G6564A105 10,725 500,000 SH   DFND 1, 2 500,000 0 0
NORWEGIAN CRUISE LINE HLDG L SHS G66721104 143,004 8,703,848 SH   DFND 1, 2 8,703,848 0 0
NOVOCURE LTD ORD SHS G6674U108 314,483 5,303,248 SH   DFND 1, 2 5,303,248 0 0
PAGSEGURO DIGITAL LTD COM CL A G68707101 721,089 20,404,396 SH   DFND 1, 2 20,391,501 0 12,895
RENAISSANCERE HOLDINGS LTD COM G7496G103 407,455 2,382,360 SH   DFND 1, 2 2,382,360 0 0
VENATOR MATLS PLC SHS G9329Z100 7,967 4,450,602 SH   DFND 1, 2 4,450,602 0 0
WILLIS TOWERS WATSON PLC LTD SHS G96629103 695,650 3,532,116 SH   DFND 1, 2 3,532,116 0 0
CHUBB LIMITED COM H1467J104 1,496,587 11,819,636 SH   DFND 1, 2 11,802,698 0 16,938
LOGITECH INTL S A SHS H50430232 398,719 6,114,904 SH   DFND 1, 2 6,114,904 0 0
TE CONNECTIVITY LTD REG SHS H84989104 1,230,388 15,087,535 SH   DFND 1, 2 15,087,535 0 0
GLOBANT S A COM L44385109 113,065 754,523 SH   DFND 1, 2 754,523 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 19,362 74,990 SH   DFND 1, 2 74,990 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210 3,022,423 8,212,620 SH   DFND 1, 2 8,191,655 0 20,965
FERRARI N V COM N3167Y103 170,260 999,177 SH   DFND 1, 2 994,361 0 4,816
LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 1,555,231 23,664,600 SH   DFND 1, 2 23,655,755 0 8,845
WRIGHT MED GROUP N V ORD SHS N96617118 26,149 879,857 SH   DFND 1, 2 879,857 0 0
YANDEX N V SHS CLASS A N97284108 508,389 10,163,721 SH   DFND 1, 2 10,163,721 0 0
ROYAL CARIBBEAN CRUISES LTD COM V7780T103 90,066 1,790,583 SH   DFND 1, 2 1,790,583 0 0
SCORPIO TANKERS INC SHS Y7542C130 4,419 345,000 SH   DFND 1, 2 345,000 0 0