The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
SQUARE INC - A COM 852234103 621,077 5,857,039 SH   SOLE   3,087,360 0 2,769,679
TESLA INC COM 88160R101 392,867 365,628 SH   SOLE   332,894 0 32,734
INVITAE CORP COM 46185L103 356,247 12,221,159 SH   SOLE   10,387,407 0 1,833,752
ZILLOW GROUP INC - C COM 98954M200 300,529 5,272,440 SH   SOLE   2,574,599 0 2,697,841
CRISPR THERAPEUTICS AG COM H17182108 269,118 3,711,970 SH   SOLE   3,159,032 0 552,938
LENDINGTREE INC COM 52603B107 267,795 991,832 SH   SOLE   525,116 0 466,716
MERCADOLIBRE INC COM 58733R102 227,100 235,337 SH   SOLE   53,666 0 181,671
ROKU INC COM 77543R102 221,081 1,905,869 SH   SOLE   1,905,869 0 0
PINTEREST INC- CLASS A COM 72352L106 206,292 9,411,133 SH   SOLE   4,934,083 0 4,477,050
2U INC COM 90214J101 201,551 5,410,777 SH   SOLE   5,410,777 0 0
ILLUMINA INC COM 452327109 198,157 548,821 SH   SOLE   399,704 0 149,117
SPLUNK INC COM 848637104 176,826 925,789 SH   SOLE   422,030 0 503,759
APPLE INC COM 037833100 172,856 475,139 SH   SOLE   0 0 475,139
EDITAS MEDICINE INC COM 28106W103 146,147 4,993,055 SH   SOLE   4,157,057 0 835,998
PROTO LABS INC COM 743713109 137,179 1,305,221 SH   SOLE   1,245,717 0 59,504
SEA LTD-ADR COM 81141R100 138,927 1,286,359 SH   SOLE   670,623 0 615,736
PAYPAL HOLDINGS INC COM 70450Y103 135,157 781,210 SH   SOLE   0 0 781,210
INTELLIA THERAPEUTICS INC COM 45826J105 123,671 6,183,547 SH   SOLE   5,016,868 0 1,166,679
AMAZON.COM INC COM 023135106 117,699 42,722 SH   SOLE   0 0 42,722
SLACK TECHNOLOGIES INC- CL A COM 83088V102 117,400 3,796,884 SH   SOLE   2,804,923 0 991,961
TERADYNE INC COM 880770102 112,810 1,361,783 SH   SOLE   1,239,096 0 122,687
XILINX INC COM 983919101 113,593 1,163,865 SH   SOLE   972,372 0 191,493
ALIBABA GROUP HOLDING-SP ADR COM 01609W102 108,711 506,337 SH   SOLE   0 0 506,337
PURE STORAGE INC - CLASS A COM 74624M102 106,703 6,295,165 SH   SOLE   5,382,522 0 912,643
COMPUGEN LTD COM M25722105 107,369 7,143,619 SH   SOLE   5,960,201 0 1,183,418
WORKDAY INC-CLASS A COM 98138H101 99,874 548,756 SH   SOLE   297,123 0 251,633
PINDUODUO INC-ADR COM 722304102 103,312 1,212,862 SH   SOLE   0 0 1,212,862
PAGERDUTY INC COM 69553P100 98,229 3,452,686 SH   SOLE   3,452,686 0 0
ZSCALER INC COM 98980G102 98,421 898,821 SH   SOLE   573,314 0 325,507
STRATASYS LTD COM M85548101 86,113 5,464,000 SH   SOLE   5,434,920 0 29,080
VERACYTE INC COM 92337F107 47,673 3,138,438 SH   SOLE   2,499,927 0 638,511
NVIDIA CORP COM 67066G104 79,168 209,169 SH   SOLE   74,756 0 134,413
IOVANCE BIOTHERAPEUTICS INC COM 462260100 75,365 2,754,568 SH   SOLE   2,009,695 0 744,873
SNAP INC - A COM 83304A106 71,916 3,069,383 SH   SOLE   602,009 0 2,467,374
CERUS CORP COM 157085101 67,178 10,697,202 SH   SOLE   8,715,248 0 1,981,954
INTERCONTINENTAL EXCHANGE IN COM 45866F104 68,634 764,386 SH   SOLE   0 0 764,386
NANOSTRING TECHNOLOGIES INC COM 63009R109 67,480 2,367,706 SH   SOLE   2,134,457 0 233,249
FACEBOOK INC-CLASS A COM 30303M102 68,527 303,283 SH   SOLE   0 0 303,283
TWILIO INC - A COM 90138F102 68,709 315,179 SH   SOLE   0 0 315,179
INTERACTIVE BROKERS GRO-CL A COM 45841N107 60,260 1,469,765 SH   SOLE   0 0 1,469,765
MATERIALISE NV-ADR COM 57667T100 55,443 2,772,169 SH   SOLE   2,759,373 0 12,796
SPOTIFY TECHNOLOGY SA COM L8681T102 54,631 212,390 SH   SOLE   183,068 0 29,322
IRIDIUM COMMUNICATIONS INC COM 46269C102 51,762 2,138,934 SH   SOLE   2,097,547 0 41,387
AUTODESK INC COM 052769106 53,806 227,652 SH   SOLE   201,121 0 26,531
TAIWAN SEMICONDUCTOR-SP ADR COM 874039100 50,747 893,280 SH   SOLE   0 0 893,280
SYROS PHARMACEUTICALS INC COM 87184Q107 38,887 4,713,594 SH   SOLE   3,776,459 0 937,135
HDFC BANK LTD-ADR COM 40415F101 46,364 1,003,546 SH   SOLE   0 0 1,003,546
SALESFORCE.COM INC COM 79466L302 45,583 246,530 SH   SOLE   63,177 0 183,353
TWIST BIOSCIENCE CORP COM 90184D100 42,456 969,315 SH   SOLE   506,531 0 462,784
ALTERYX INC - CLASS A COM 02156B103 42,125 258,116 SH   SOLE   0 0 258,116
GUIDEWIRE SOFTWARE INC COM 40171V100 37,737 381,186 SH   SOLE   0 0 381,186
SERES THERAPEUTICS INC COM 81750R102 34,781 7,400,245 SH   SOLE   5,872,466 0 1,527,779
DOCUSIGN INC COM 256163106 33,575 195,486 SH   SOLE   0 0 195,486
INTUIT INC COM 461202103 31,493 108,643 SH   SOLE   0 0 108,643
VERISK ANALYTICS INC COM 92345Y106 28,945 173,347 SH   SOLE   0 0 173,347
TRANSUNION COM 89400J107 27,288 328,771 SH   SOLE   0 0 328,771
LENDINGCLUB CORP COM 52603A208 27,050 6,092,344 SH   SOLE   3,834,824 0 2,257,520
CAREDX INC COM 14167L103 19,120 708,140 SH   SOLE   0 0 708,140
NETFLIX INC COM 64110L106 21,674 47,720 SH   SOLE   37,979 0 9,741
REGENERON PHARMACEUTICALS COM 75886F107 21,335 35,012 SH   SOLE   0 0 35,012
GUARDANT HEALTH INC COM 40131M109 20,611 261,722 SH   SOLE   0 0 261,722
TWITTER INC COM 90184L102 19,771 657,925 SH   SOLE   542,659 0 115,266
TELADOC HEALTH INC COM 87918A105 19,002 99,627 SH   SOLE   28,027 0 71,600
AEROVIRONMENT INC COM 008073108 17,763 233,692 SH   SOLE   51,669 0 182,023
FATE THERAPEUTICS INC COM 31189P102 17,085 527,311 SH   SOLE   0 0 527,311
TRIMBLE INC COM 896239100 17,567 423,296 SH   SOLE   0 0 423,296
10X GENOMICS INC-CLASS A COM 88025U109 17,755 206,213 SH   SOLE   0 0 206,213
VERTEX PHARMACEUTICALS INC COM 92532F100 17,737 62,563 SH   SOLE   0 0 62,563
INCYTE CORP COM 45337C102 16,386 161,149 SH   SOLE   0 0 161,149
THERMO FISHER SCIENTIFIC INC COM 883556102 15,016 42,569 SH   SOLE   0 0 42,569
SCHWAB (CHARLES) CORP COM 808513105 15,082 452,637 SH   SOLE   0 0 452,637
JD.COM INC-ADR COM 47215P106 14,817 248,021 SH   SOLE   0 0 248,021
IONIS PHARMACEUTICALS INC COM 462222100 14,272 246,919 SH   SOLE   0 0 246,919
EXONE CO/THE COM 302104104 13,083 1,635,394 SH   SOLE   1,635,394 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 13,692 233,604 SH   SOLE   0 0 233,604
INOVIO PHARMACEUTICALS INC COM 45773H201 13,862 583,657 SH   SOLE   0 0 583,657
BHP GROUP PLC-ADR COM 05545E209 13,005 319,229 SH   SOLE   319,229 0 0
CELLECTIS - ADR COM 15117K103 12,687 728,282 SH   SOLE   0 0 728,282
DEERE & CO COM 244199105 11,616 74,727 SH   SOLE   0 0 74,727
RIO TINTO PLC-SPON ADR COM 767204100 11,804 212,838 SH   SOLE   212,838 0 0
CATERPILLAR INC COM 149123101 11,053 87,511 SH   SOLE   0 0 87,511
FLIR SYSTEMS INC COM 302445101 10,879 273,337 SH   SOLE   0 0 273,337
ALPHABET INC-CL C COM 02079K107 10,992 7,817 SH   SOLE   0 0 7,817
CORTEVA INC COM 22052L104 9,847 393,416 SH   SOLE   131,884 0 261,532
PERSONALIS INC COM 71535D106 7,653 789,742 SH   SOLE   0 0 789,742
SAREPTA THERAPEUTICS INC COM 803607100 9,626 62,001 SH   SOLE   0 0 62,001
KRATOS DEFENSE & SECURITY COM 50077B207 9,475 618,446 SH   SOLE   0 0 618,446
SCHRODINGER INC COM 80810D103 9,226 101,380 SH   SOLE   0 0 101,380
CODEXIS INC COM 192005106 8,204 800,367 SH   SOLE   0 0 800,367
NXP SEMICONDUCTORS NV COM N6596X109 8,806 79,183 SH   SOLE   0 0 79,183
ADAPTIVE BIOTECHNOLOGIES COM 00650F109 7,039 166,573 SH   SOLE   0 0 166,573
BAIDU INC - SPON ADR COM 056752108 7,606 63,892 SH   SOLE   0 0 63,892
CHEVRON CORP COM 166764100 7,140 80,775 SH   SOLE   78,928 0 1,847
BARRICK GOLD CORP COM 067901108 7,104 263,893 SH   SOLE   263,893 0 0
ARCTURUS THERAPEUTICS HOLDIN COM 03969T109 6,559 143,487 SH   SOLE   0 0 143,487
NUTRIEN LTD COM 67077M108 6,687 214,336 SH   SOLE   214,336 0 0
TOTAL SA-SPON ADR COM 89151E109 6,806 179,854 SH   SOLE   179,854 0 0
EXXON MOBIL CORP COM 30231G102 6,748 152,227 SH   SOLE   148,960 0 3,267
CHINA BIOLOGIC PRODUCTS HOLD COM G21515104 1 65,463 SH   SOLE   0 0 65,463
UNITED PARCEL SERVICE-CL B COM 911312106 6,347 54,423 SH   SOLE   0 0 54,423
ORGANOVO HOLDINGS INC COM 68620A104 5,388 9,796,442 SH   SOLE   7,428,211 0 2,368,231
SCHLUMBERGER LTD COM 806857108 5,644 311,456 SH   SOLE   306,730 0 4,726
B2GOLD CORP COM 11777Q209 5,586 985,119 SH   SOLE   985,119 0 0
APTIV PLC COM G6095L109 5,293 68,734 SH   SOLE   0 0 68,734
ALAMOS GOLD INC-CLASS A COM 011532108 4,923 553,185 SH   SOLE   553,185 0 0
DOMINO'S PIZZA INC COM 25754A201 4,682 12,960 SH   SOLE   0 0 12,960
ANGLOGOLD ASHANTI-SPON ADR COM 035128206 4,934 167,871 SH   SOLE   167,871 0 0
NEWMONT CORP COM 651639106 4,955 79,996 SH   SOLE   79,996 0 0
FREEPORT-MCMORAN INC COM 35671D857 4,578 400,887 SH   SOLE   400,887 0 0
INTERNATIONAL PAPER CO COM 460146103 4,402 127,268 SH   SOLE   127,268 0 0
AGNICO EAGLE MINES LTD COM 008474108 4,443 70,289 SH   SOLE   70,289 0 0
LINDE PLC COM G5494J103 4,275 20,497 SH   SOLE   20,497 0 0
GARMIN LTD COM H2906T109 3,936 42,784 SH   SOLE   0 0 42,784
SYNOPSYS INC COM 871607107 4,165 21,443 SH   SOLE   0 0 21,443
ANSYS INC COM 03662Q105 3,798 14,412 SH   SOLE   0 0 14,412
BP PLC-SPONS ADR COM 055622104 3,754 162,635 SH   SOLE   162,635 0 0
ROYAL DUTCH SHELL-SPON ADR-A COM 780259206 3,713 115,157 SH   SOLE   115,157 0 0
ROCKWELL AUTOMATION INC COM 773903109 3,153 17,024 SH   SOLE   0 0 17,024
SUNCOR ENERGY INC COM 867224107 3,371 201,850 SH   SOLE   195,800 0 6,050
WEYERHAEUSER CO COM 962166104 3,192 149,507 SH   SOLE   149,507 0 0
CONCHO RESOURCES INC COM 20605P101 3,229 63,309 SH   SOLE   61,251 0 2,058
HALLIBURTON CO COM 406216101 3,060 238,907 SH   SOLE   235,420 0 3,487
ARCHER-DANIELS-MIDLAND CO COM 039483102 2,984 76,814 SH   SOLE   76,814 0 0
NUCOR CORP COM 670346105 2,965 73,702 SH   SOLE   73,702 0 0
BAKER HUGHES CO COM 05722G100 2,694 185,805 SH   SOLE   181,846 0 3,959
STEEL DYNAMICS INC COM 858119100 2,557 99,900 SH   SOLE   99,900 0 0
DIAMONDBACK ENERGY INC COM 25278X109 2,296 55,592 SH   SOLE   53,297 0 2,295
CALYXT INC COM 13173L107 2,098 465,189 SH   SOLE   0 0 465,189
EOG RESOURCES INC COM 26875P101 2,156 43,998 SH   SOLE   42,165 0 1,833
TECK RESOURCES LTD-CLS B COM 878742204 2,097 210,728 SH   SOLE   210,728 0 0
MARATHON PETROLEUM CORP COM 56585A102 2,162 58,445 SH   SOLE   56,142 0 2,303
PACKAGING CORP OF AMERICA COM 695156109 1,960 21,756 SH   SOLE   21,756 0 0
VIRGIN GALACTIC HOLDINGS INC COM 92766K106 2,086 125,578 SH   SOLE   0 0 125,578
UNIVAR SOLUTIONS INC COM 91336L107 1,692 116,695 SH   SOLE   116,695 0 0
CONOCOPHILLIPS COM 20825C104 1,901 45,808 SH   SOLE   45,808 0 0
PIONEER NATURAL RESOURCES CO COM 723787107 1,804 18,564 SH   SOLE   17,702 0 862
OCCIDENTAL PETROLEUM CORP COM 674599105 1,747 95,993 SH   SOLE   92,992 0 3,001
ELBIT SYSTEMS LTD COM M3760D101 1,544 12,918 SH   SOLE   0 0 12,918
PHILLIPS 66 COM 718546104 1,699 24,032 SH   SOLE   24,032 0 0
CANADIAN NATURAL RESOURCES COM 136385101 1,651 97,094 SH   SOLE   97,094 0 0
VALERO ENERGY CORP COM 91913Y100 1,632 28,284 SH   SOLE   28,284 0 0
TECHNIPFMC PLC COM G87110105 1,571 228,613 SH   SOLE   223,426 0 5,187
CF INDUSTRIES HOLDINGS INC COM 125269100 1,494 56,199 SH   SOLE   56,199 0 0
CABOT OIL & GAS CORP COM 127097103 1,580 93,632 SH   SOLE   88,656 0 4,976
WILLIAMS COS INC COM 969457100 1,455 78,100 SH   SOLE   78,100 0 0
NOMAD FOODS LTD COM G6564A105 1,413 68,430 SH   SOLE   68,430 0 0
HESS CORP COM 42809H107 1,372 27,338 SH   SOLE   27,338 0 0
SOUTHERN COPPER CORP COM 84265V105 1,380 35,059 SH   SOLE   35,059 0 0
BUNGE LTD COM G16962105 1,112 27,795 SH   SOLE   27,795 0 0
LIBERTY OILFIELD SERVICES -A COM 53115L104 963 199,806 SH   SOLE   196,045 0 3,761
XYLEM INC COM 98419M100 1,031 17,185 SH   SOLE   17,185 0 0
ALBEMARLE CORP COM 012653101 973 13,608 SH   SOLE   13,608 0 0
PLURISTEM THERAPEUTICS INC COM 72940R300 993 114,124 SH   SOLE   0 0 114,124
AIR PRODUCTS & CHEMICALS INC COM 009158106 921 4,016 SH   SOLE   4,016 0 0
CACTUS INC - A COM 127203107 839 46,211 SH   SOLE   46,211 0 0
NOBLE ENERGY INC COM 655044105 883 100,677 SH   SOLE   100,677 0 0
OCEANEERING INTL INC COM 675232102 854 137,911 SH   SOLE   137,911 0 0
MOSAIC CO/THE COM 61945C103 856 68,838 SH   SOLE   68,838 0 0
OIL STATES INTERNATIONAL INC COM 678026105 766 175,386 SH   SOLE   171,284 0 4,102
CHINA PETROLEUM & CHEM-ADR COM 16941R108 740 17,837 SH   SOLE   17,837 0 0
AQUABOUNTY TECHNOLOGIES COM 03842K200 622 197,543 SH   SOLE   0 0 197,543
ONEOK INC COM 682680103 618 18,804 SH   SOLE   16,463 0 2,341
PETROLEO BRASILEIRO-SPON ADR COM 71654V408 536 65,721 SH   SOLE   65,721 0 0
DRIL-QUIP INC COM 262037104 147 18,398 SH   SOLE   18,398 0 0
BANCO BRADESCO-ADR COM 059460303 474 129,880 SH   SOLE   0 0 129,880
LOCKHEED MARTIN CORP COM 539830109 458 1,265 SH   SOLE   0 0 1,265
HELMERICH & PAYNE COM 423452101 442 23,283 SH   SOLE   22,510 0 773
L3HARRIS TECHNOLOGIES INC COM 502431109 335 1,992 SH   SOLE   0 0 1,992
HEICO CORP COM 422806109 263 2,924 SH   SOLE   0 0 2,924
BOEING CO/THE COM 097023105 212 1,166 SH   SOLE   0 0 1,166
HONEYWELL INTERNATIONAL INC COM 438516106 212 1,489 SH   SOLE   0 0 1,489
AEROJET ROCKETDYNE HOLDINGS COM 007800105 202 5,281 SH   SOLE   0 0 5,281
SPIRIT AEROSYSTEMS HOLD-CL A COM 848574109 184 7,870 SH   SOLE   0 0 7,870
TELEDYNE TECHNOLOGIES INC COM 879360105 111 410 SH   SOLE   0 0 410