The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
SIMON PPTY GROUP INC NEW COM 828806109 1,593 23,299 SH   SOLE   23,299 0 0
LULULEMON ATHLETICA INC COM 550021109 10,927 35,019 SH   SOLE   35,019 0 0
EXELON CORP COM 30161N101 4,059 111,840 SH   SOLE   111,840 0 0
SANOFI SPONSORED ADR 80105N105 3 49 SH   SOLE 1 0 0 49
EXACT SCIENCES CORP NOTE 0.375% 3/0 30063PAC9 2,070 2,150 PRN   SOLE   2,150 0 0
KEURIG DR PEPPER INC COM 49271V100 813 28,616 SH   SOLE   28,616 0 0
LOGMEIN INC COM 54142L109 4,596 54,213 SH   SOLE   54,213 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 7 111 SH   SOLE 1 0 0 111
GILEAD SCIENCES INC COM 375558103 130,033 1,689,988 SH   SOLE   1,689,988 0 0
ROSS STORES INC COM 778296103 1,942 22,783 SH   SOLE   22,783 0 0
OCCIDENTAL PETE CORP COM 674599105 1,079 58,932 SH   SOLE   58,932 0 0
VULCAN MATLS CO COM 929160109 11,110 95,892 SH   SOLE   95,892 0 0
ORACLE CORP COM 68389X105 33,813 611,746 SH   SOLE   611,746 0 0
GOLD FIELDS LTD SPONSORED ADR 38059T106 239 25,433 SH   SOLE   25,433 0 0
BAXTER INTL INC COM 071813109 4,418 51,314 SH   SOLE   51,314 0 0
UNITED PARCEL SERVICE INC CL B 911312106 9,794 88,087 SH   SOLE   88,087 0 0
FORD MTR CO DEL COM 345370860 1,634 268,759 SH   SOLE   268,759 0 0
CDW CORP COM 12514G108 9,618 82,786 SH   SOLE   82,786 0 0
UNITEDHEALTH GROUP INC COM 91324P102 1 4 SH   SOLE 1 0 0 4
MICRON TECHNOLOGY INC COM 595112103 4,631 89,885 SH   SOLE   89,885 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 14,633 570,000 SH   SOLE   570,000 0 0
VODAFONE GROUP PLC NEW SPONSORED ADR 92857W308 1 36 SH   SOLE 1 0 0 36
SYSCO CORP COM 871829107 2,124 38,854 SH   SOLE   38,854 0 0
SQUARE INC NOTE 0.500% 5/1 852234AD5 2,679 1,800 PRN   SOLE   1,800 0 0
NVR INC COM 62944T105 668 205 SH   SOLE   205 0 0
KELLOGG CO COM 487836108 4,220 63,872 SH   SOLE   63,872 0 0
AT&T INC COM 00206R102 6 183 SH   SOLE 1 0 0 183
MASCO CORP COM 574599106 2 36 SH   SOLE 1 0 0 36
HILL ROM HLDGS INC COM 431475102 15,891 144,749 SH   SOLE   144,749 0 0
AMERICAN AIRLS GROUP INC COM 02376R102 170 13,000 SH   SOLE   13,000 0 0
MICROSOFT CORP COM 594918104 16 81 SH   SOLE 1 0 0 81
ACCELERON PHARMA INC COM 00434H108 2 24 SH   SOLE 1 0 0 24
ZYMEWORKS INC COM 98985W102 12,425 344,466 SH   SOLE   344,466 0 0
APPLIED THERAPEUTICS INC COM 03828A101 2,892 80,000 SH   SOLE   80,000 0 0
LILLY ELI & CO COM 532457108 47,618 290,023 SH   SOLE   290,023 0 0
VERISK ANALYTICS INC COM 92345Y106 1 8 SH   SOLE 1 0 0 8
APPLIED MATLS INC COM 038222105 1 16 SH   SOLE 1 0 0 16
BIOMARIN PHARMACEUTICAL INC NOTE 0.599% 8/0 09061GAH4 3,198 2,600 PRN   SOLE   2,600 0 0
TYLER TECHNOLOGIES INC COM 902252105 881 2,541 SH   SOLE   2,541 0 0
CITIGROUP INC COM NEW 172967424 3 49 SH   SOLE 1 0 0 49
HANNON ARMSTRONG SUST INFR C COM 41068X100 1 47 SH   SOLE 1 0 0 47
DOVER CORP COM 260003108 1,609 16,661 SH   SOLE   16,661 0 0
CENTENE CORP DEL COM 15135B101 2,209 34,752 SH   SOLE   34,752 0 0
AMERICAN EXPRESS CO COM 025816109 23,154 243,205 SH   SOLE   243,205 0 0
COPART INC COM 217204106 2,336 28,049 SH   SOLE   28,049 0 0
ON SEMICONDUCTOR CORP NOTE 1.625%10/1 682189AP0 2,441 2,000 PRN   SOLE   2,000 0 0
VORNADO RLTY TR SH BEN INT 929042109 863 22,589 SH   SOLE   22,589 0 0
CISCO SYS INC COM 17275R102 4,473 3,602 PRN   SOLE   3,602 0 0
AMERICAN WTR WKS CO INC NEW COM 030420103 28,487 221,400 SH   SOLE   221,400 0 0
YAMANA GOLD INC COM 98462Y100 95 17,590 SH   SOLE   17,590 0 0
ZENDESK INC COM 98936J101 219 2,470 SH   SOLE   2,470 0 0
ARGENX SE SPONSORED ADR 04016X101 13,492 59,901 SH   SOLE   59,901 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 0 38 SH   SOLE 1 0 0 38
INVITATION HOMES INC COM 46187W107 823 29,909 SH   SOLE   29,909 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 1 34 SH   SOLE 1 0 0 34
PRICE T ROWE GROUP INC COM 74144T108 10,755 87,080 SH   SOLE   87,080 0 0
TOPBUILD CORP COM 89055F103 9,268 81,458 SH   SOLE   81,458 0 0
CLOROX CO DEL COM 189054109 2 7 SH   SOLE 1 0 0 7
SALESFORCE COM INC COM 79466L302 1,972 1,950 PRN   SOLE   1,950 0 0
LEGG MASON INC COM 524901105 9,114 183,184 SH   SOLE   183,184 0 0
MAXIM INTEGRATED PRODS INC COM 57772K101 530 8,747 SH   SOLE   8,747 0 0
IBERIABANK CORP COM 450828108 17,046 374,285 SH   SOLE   374,285 0 0
FEDERAL REALTY INVT TR SH BEN INT NEW 313747206 332 3,892 SH   SOLE   3,892 0 0
FLEETCOR TECHNOLOGIES INC COM 339041105 1,035 4,113 SH   SOLE   4,113 0 0
WORKDAY INC NOTE 0.250%10/0 98138HAF8 3,316 2,400 PRN   SOLE   2,400 0 0
AMERISOURCEBERGEN CORP COM 03073E105 1,131 11,224 SH   SOLE   11,224 0 0
AFYA LTD CL A COM G01125106 12,635 539,000 SH   SOLE   539,000 0 0
MACROGENICS INC COM 556099109 0 16 SH   SOLE 1 0 0 16
OREILLY AUTOMOTIVE INC COM 67103H107 1,698 4,026 SH   SOLE   4,026 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 7,064 31,096 SH   SOLE   31,096 0 0
CREDICORP LTD COM G2519Y108 12,806 95,800 SH   SOLE   95,800 0 0
SUN CMNTYS INC COM 866674104 673 4,963 SH   SOLE   4,963 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 13,542 407,020 SH   SOLE   407,020 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 0 24 SH   SOLE 1 0 0 24
PAYPAL HLDGS INC COM 70450Y103 2 10 SH   SOLE 1 0 0 10
F M C CORP COM NEW 302491303 1,024 10,279 SH   SOLE   10,279 0 0
MANULIFE FINL CORP COM 56501R106 4,608 339,821 SH   SOLE   339,821 0 0
WASTE CONNECTIONS INC COM 94106B101 2 16 SH   SOLE 1 0 0 16
ERICSSON ADR B SEK 10 294821608 2,172 233,516 SH   SOLE   233,516 0 0
HERON THERAPEUTICS INC COM 427746102 18,815 1,278,972 SH   SOLE   1,278,972 0 0
Y-MABS THERAPEUTICS INC COM 984241109 7,127 164,979 SH   SOLE   164,979 0 0
COGNIZANT TECHNOLOGY SOLUTIO CL A 192446102 6,952 122,347 SH   SOLE   122,347 0 0
BAOZUN INC SPONSORED ADR 06684L103 19,918 518,000 SH   SOLE   518,000 0 0
XENCOR INC COM 98401F105 14,999 463,068 SH   SOLE   463,068 0 0
LOEWS CORP COM 540424108 1,159 33,795 SH   SOLE   33,795 0 0
POWER INTEGRATIONS INC COM 739276103 7,929 67,122 SH   SOLE   67,122 0 0
TWITTER INC COM 90184L102 3,743 12,541,400 SH Call SOLE   12,541,400 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 4,516 228,764 SH   SOLE   228,764 0 0
PROCTER AND GAMBLE CO COM 742718109 102,755 859,331 SH   SOLE   859,331 0 0
PAYCOM SOFTWARE INC COM 70432V102 850 2,744 SH   SOLE   2,744 0 0
BROADCOM INC COM 11135F101 49,970 158,321 SH   SOLE   158,321 0 0
NEWMONT CORP COM 651639106 16,256 263,291 SH   SOLE   263,291 0 0
PRICELINE GRP INC NOTE 0.900% 9/1 741503AX4 13,296 12,522 PRN   SOLE   12,522 0 0
EXACT SCIENCES CORP COM 30063P105 16,338 187,909 SH   SOLE   187,909 0 0
US BANCORP DEL COM NEW 902973304 3,778 102,599 SH   SOLE   102,599 0 0
MICROCHIP TECHNOLOGY INC. COM 595017104 6,472 61,450 SH   SOLE   61,450 0 0
MICRON TECHNOLOGY INC COM 595112103 1 22 SH   SOLE 1 0 0 22
IQIYI INC SPONSORED ADS 46267X108 2,012 1,900 PRN   SOLE   1,900 0 0
DOLLAR TREE INC COM 256746108 1,158 12,498 SH   SOLE   12,498 0 0
CARDINAL HEALTH INC COM 14149Y108 1 22 SH   SOLE 1 0 0 22
ACCENTURE PLC IRELAND SHS CLASS A G1151C101 2 7 SH   SOLE 1 0 0 7
AUTOLIV INC COM 052800109 346 5,360 SH   SOLE   5,360 0 0
ENPHASE ENERGY INC COM 29355A107 1 30 SH   SOLE 1 0 0 30
AUTODESK INC COM 052769106 3 11 SH   SOLE 1 0 0 11
HOLOGIC INC COM 436440101 4 70 SH   SOLE 1 0 0 70
NOVO-NORDISK A S ADR 670100205 3 45 SH   SOLE 1 0 0 45
DECIPHERA PHARMACEUTICALS IN COM 24344T101 15,032 251,703 SH   SOLE   251,703 0 0
CBOE GLOBAL MARKETS INC COM 12503M108 611 6,548 SH   SOLE   6,548 0 0
COSTAR GROUP INC COM 22160N109 1,261 1,774 SH   SOLE   1,774 0 0
EIDOS THERAPEUTICS INC COM 28249H104 8,854 185,721 SH   SOLE   185,721 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 1 51 SH   SOLE 1 0 0 51
APREA THERAPEUTICS INC COM 03836J102 1 15 SH   SOLE 1 0 0 15
RENEWABLE ENERGY GROUP INC COM NEW 75972A301 835 33,676 SH   SOLE   33,676 0 0
BANCOLOMBIA S A SPON ADR PREF 05968L102 12,929 491,378 SH   SOLE   491,378 0 0
BARRICK GOLD CORPORATION COM 067901108 2,306 85,982 SH   SOLE   85,982 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 2 43 SH   SOLE 1 0 0 43
ON SEMICONDUCTOR CORP COM 682189105 24,663 1,244,308 SH   SOLE   1,244,308 0 0
NOVOCURE LTD ORD SHS G6674U108 1 9 SH   SOLE 1 0 0 9
GSX TECHEDU INC SPONSORED ADS 36257Y109 300 5,000 SH   SOLE   5,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 45,593 369,640 SH   SOLE   369,640 0 0
CAMPBELL SOUP CO COM 134429109 12,617 254,218 SH   SOLE   254,218 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 4,773 228,575 SH   SOLE   228,575 0 0
OLD DOMINION FREIGHT LINE IN COM 679580100 7,086 41,779 SH   SOLE   41,779 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 1 25 SH   SOLE 1 0 0 25
AMERIPRISE FINL INC COM 03076C106 11,001 73,316 SH   SOLE   73,316 0 0
PTC INC COM 69370C100 21,801 280,245 SH   SOLE   280,245 0 0
SYNOPSYS INC COM 871607107 4 19 SH   SOLE 1 0 0 19
GOLDMAN SACHS GROUP INC COM 38141G104 8,821 44,632 SH   SOLE   44,632 0 0
TOPBUILD CORP COM 89055F103 2 20 SH   SOLE 1 0 0 20
AMICUS THERAPEUTICS INC COM 03152W109 11,184 741,588 SH   SOLE   741,588 0 0
RADIUS HEALTH INC COM NEW 750469207 4,253 312,025 SH   SOLE   312,025 0 0
MIRATI THERAPEUTICS INC COM 60468T105 12,566 110,057 SH   SOLE   110,057 0 0
LAS VEGAS SANDS CORP COM 517834107 810 17,785 SH   SOLE   17,785 0 0
TILLYS INC CL A 886885102 680 120,000 SH   SOLE   120,000 0 0
BIO RAD LABS INC CL A 090572207 46,568 103,138 SH   SOLE   103,138 0 0
DUPONT DE NEMOURS INC COM 26614N102 8,915 167,790 SH   SOLE   167,790 0 0
COMCAST CORP NEW CL A 20030N101 4 96 SH   SOLE 1 0 0 96
PPG INDS INC COM 693506107 2 18 SH   SOLE 1 0 0 18
CIGNA CORP NEW COM 125523100 12,187 64,943 SH   SOLE   64,943 0 0
MCCORMICK & CO INC COM NON VTG 579780206 10,595 59,050 SH   SOLE   59,050 0 0
ON SEMICONDUCTOR CORP COM 682189105 2 82 SH   SOLE 1 0 0 82
LAMB WESTON HLDGS INC COM 513272104 623 9,746 SH   SOLE   9,746 0 0
HUTCHISON CHINA MEDITECH LTD SPONSORED ADR 44842L103 965 35,000 SH   SOLE   35,000 0 0
PROLOGIS INC. COM 74340W103 22,765 243,909 SH   SOLE   243,909 0 0
OWENS CORNING NEW COM 690742101 2,116 37,939 SH   SOLE   37,939 0 0
HEWLETT PACKARD ENTERPRISE C COM 42824C109 1,330 136,735 SH   SOLE   136,735 0 0
RINGCENTRAL INC CL A 76680R206 1,240 4,352 SH   SOLE   4,352 0 0
MERCK & CO. INC COM 58933Y105 157,637 2,038,413 SH   SOLE   2,038,413 0 0
VIPSHOP HOLDINGS LIMITED SPONSORED ADS A 92763W103 34,127 1,714,000 SH   SOLE   1,714,000 0 0
FORTIVE CORP COM 34959J108 2,200 32,519 SH   SOLE   32,519 0 0
INGREDION INC COM 457187102 1 11 SH   SOLE 1 0 0 11
THERMO FISHER SCIENTIFIC INC COM 883556102 96,500 266,313 SH   SOLE   266,313 0 0
GLOBAL PMTS INC COM 37940X102 3,299 19,446 SH   SOLE   19,446 0 0
ASURE SOFTWARE INC COM 04649U102 103 16,000 SH   SOLE   16,000 0 0
RIO TINTO PLC SPONSORED ADR 767204100 1,416 25,195 SH   SOLE   25,195 0 0
EXPEDITORS INTL WASH INC COM 302130109 895 11,776 SH   SOLE   11,776 0 0
BAKER HUGHES COMPANY CL A 05722G100 5,121 332,726 SH   SOLE   332,726 0 0
CIA ENERGETICA DE MINAS GERA SP ADR N-V PFD 204409601 145 70,583 SH   SOLE   70,583 0 0
TARGET CORP COM 87612E106 4,409 36,758 SH   SOLE   36,758 0 0
NORTONLIFELOCK INC COM 668771108 7,203 363,219 SH   SOLE   363,219 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 0 142 SH   SOLE 1 0 0 142
CHEVRON CORP NEW COM 166764100 4,164 46,667 SH   SOLE   46,667 0 0
HCA HEALTHCARE INC COM 40412C101 12,928 133,194 SH   SOLE   133,194 0 0
UGI CORP NEW COM 902681105 1,301 40,916 SH   SOLE   40,916 0 0
JPMORGAN CHASE & CO COM 46625H100 3 36 SH   SOLE 1 0 0 36
E TRADE FINANCIAL CORP COM NEW 269246401 9,859 198,244 SH   SOLE   198,244 0 0
NOVO-NORDISK A S ADR 670100205 1,608 24,558 SH   SOLE   24,558 0 0
GODADDY INC CL A 380237107 622 8,479 SH   SOLE   8,479 0 0
TOTAL S.A. SPONSORED ADS 89151E109 2,602 67,652 SH   SOLE   67,652 0 0
PERSONALIS INC COM 71535D106 6,793 523,689 SH   SOLE   523,689 0 0
XPO LOGISTICS INC COM 983793100 503 6,510 SH   SOLE   6,510 0 0
TRICIDA INC COM 89610F101 5,263 191,500 SH   SOLE   191,500 0 0
BUNGE LIMITED COM G16962105 749 18,201 SH   SOLE   18,201 0 0
GENERAL ELECTRIC CO COM 369604103 4,482 656,196 SH   SOLE   656,196 0 0
TREX CO INC COM 89531P105 7,753 59,607 SH   SOLE   59,607 0 0
ISHARES TR U.S. PHARMA ETF 464288836 277 1,800 SH   SOLE   1,800 0 0
SUNCOR ENERGY INC NEW COM 867224107 1,012 60,240 SH   SOLE   60,240 0 0
NEXTERA ENERGY PARTNERS LP COM UNIT PART IN 65341B106 9,237 180,129 SH   SOLE   180,129 0 0
KRAFT HEINZ CO COM 500754106 1,489 46,704 SH   SOLE   46,704 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 10 28 SH   SOLE 1 0 0 28
TELUS CORPORATION COM 87971M103 2,715 162,397 SH   SOLE   162,397 0 0
CINTAS CORP COM 172908105 1,866 7,006 SH   SOLE   7,006 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 808 34,000 SH   SOLE   34,000 0 0
JPMORGAN CHASE & CO COM 46625H100 60,774 646,096 SH   SOLE   646,096 0 0
WESTERN DIGITAL CORP. NOTE 1.500% 2/0 958102AP0 4,087 4,300 PRN   SOLE   4,300 0 0
ALLSTATE CORP COM 020002101 2 16 SH   SOLE 1 0 0 16
LEAR CORP COM NEW 521865204 221 2,023 SH   SOLE   2,023 0 0
AMBARELLA INC SHS G037AX101 11,341 247,613 SH   SOLE   247,613 0 0
ELANCO ANIMAL HEALTH INC COM 28414H103 577 26,909 SH   SOLE   26,909 0 0
TRAVELERS COMPANIES INC COM 89417E109 2 20 SH   SOLE 1 0 0 20
HUNTINGTON INGALLS INDS INC COM 446413106 5,629 32,260 SH   SOLE   32,260 0 0
CADENCE DESIGN SYSTEM INC COM 127387108 5 50 SH   SOLE 1 0 0 50
PROGRESSIVE CORP OHIO COM 743315103 5,646 70,474 SH   SOLE   70,474 0 0
CRYOLIFE INC COM 228903100 794 41,403 SH   SOLE   41,403 0 0
LOOP INDS INC COM 543518104 792 88,025 SH   SOLE   88,025 0 0
CHEGG INC NOTE 0.125% 3/1 163092AD1 2,380 1,664 PRN   SOLE   1,664 0 0
UNITED MICROELECTRONICS CORP SPON ADR NEW 910873405 94 35,501 SH   SOLE   35,501 0 0
VEREIT INC COM 92339V100 673 104,689 SH   SOLE   104,689 0 0
QIWI PLC SPON ADR REP B 74735M108 6,648 383,800 SH   SOLE   383,800 0 0
DENTSPLY SIRONA INC COM 24906P109 869 19,715 SH   SOLE   19,715 0 0
SOLAREDGE TECHNOLOGIES INC COM 83417M104 8,484 61,127 SH   SOLE   61,127 0 0
BHP GROUP LTD SPONSORED ADS 088606108 3 68 SH   SOLE 1 0 0 68
SCHWAB CHARLES CORP COM 808513105 2,498 74,029 SH   SOLE   74,029 0 0
HORMEL FOODS CORP COM 440452100 1,386 28,707 SH   SOLE   28,707 0 0
CYBERARK SOFTWARE LTD SHS M2682V108 1 10 SH   SOLE 1 0 0 10
BLUEBIRD BIO INC COM 09609G100 1 16 SH   SOLE 1 0 0 16
INTUIT COM 461202103 17,733 59,868 SH   SOLE   59,868 0 0
DISH NETWORK CORPORATION CL A 25470M109 488 14,135 SH   SOLE   14,135 0 0
MITSUBISHI UFJ FINL GROUP IN SPONSORED ADS 606822104 1 190 SH   SOLE 1 0 0 190
TAL EDUCATION GROUP SPONSORED ADS 874080104 6,714 98,183 SH   SOLE   98,183 0 0
PRINCIPIA BIOPHARMA INC COM 74257L108 2,491 41,658 SH   SOLE   41,658 0 0
STRYKER CORPORATION COM 863667101 8,084 44,860 SH   SOLE   44,860 0 0
PROCTER AND GAMBLE CO COM 742718109 3 28 SH   SOLE 1 0 0 28
CERNER CORP COM 156782104 10,573 154,224 SH   SOLE   154,224 0 0
BROOKFIELD RENEWABLE PARTNER PARTNERSHIP UNIT G16258108 1,070 22,343 SH   SOLE   22,343 0 0
ISIS PHARMACEUTICALS INC DEL NOTE 1.000%11/1 464337AJ3 2,320 2,100 PRN   SOLE   2,100 0 0
KURA ONCOLOGY INC COM 50127T109 0 28 SH   SOLE 1 0 0 28
ARENA PHARMACEUTICALS INC COM NEW 040047607 28,585 454,075 SH   SOLE   454,075 0 0
REDHILL BIOPHARMA LTD SPONSORED ADS 757468103 553 82,523 SH   SOLE   82,523 0 0
EQUINIX INC COM 29444U700 20,046 28,542 SH   SOLE   28,542 0 0
NVIDIA CORPORATION COM 67066G104 1,516 1,200 PRN   SOLE   1,200 0 0
TRIMBLE INC COM 896239100 16,924 391,841 SH   SOLE   391,841 0 0
AGILENT TECHNOLOGIES INC COM 00846U101 1 13 SH   SOLE 1 0 0 13
MARKETAXESS HLDGS INC COM 57060D108 1,072 2,140 SH   SOLE   2,140 0 0
PIONEER NAT RES CO COM 723787107 1,234 12,635 SH   SOLE   12,635 0 0
ADVANCED DRAIN SYS INC DEL COM 00790R104 12,201 246,970 SH   SOLE   246,970 0 0
EXACT SCIENCES CORP COM 30063P105 2 19 SH   SOLE 1 0 0 19
GILEAD SCIENCES INC COM 375558103 3 37 SH   SOLE 1 0 0 37
STATE STR CORP COM 857477103 7,879 123,973 SH   SOLE   123,973 0 0
EXXON MOBIL CORP COM 30231G102 36,449 815,013 SH   SOLE   815,013 0 0
SPDR SER TR S&P BIOTECH 78464A870 254 2,265 SH   SOLE   2,265 0 0
TG THERAPEUTICS INC COM 88322Q108 30,137 1,547,001 SH   SOLE   1,547,001 0 0
AIR PRODS & CHEMS INC COM 009158106 35,917 148,743 SH   SOLE   148,743 0 0
DISCOVER FINL SVCS COM 254709108 6,171 123,197 SH   SOLE   123,197 0 0
ARCTURUS THERAPEUTICS HLDG I COM 03969T109 3,726 79,720 SH   SOLE   79,720 0 0
KB FINL GROUP INC SPONSORED ADR 48241A105 209 7,513 SH   SOLE   7,513 0 0
INTERPUBLIC GROUP COS INC COM 460690100 1 68 SH   SOLE 1 0 0 68
SYNDAX PHARMACEUTICALS INC COM 87164F105 5,149 347,424 SH   SOLE   347,424 0 0
HILL ROM HLDGS INC COM 431475102 1 10 SH   SOLE 1 0 0 10
AUTOZONE INC COM 053332102 7,948 7,045 SH   SOLE   7,045 0 0
MOODYS CORP COM 615369105 4,665 16,978 SH   SOLE   16,978 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 24,431 156,584 SH   SOLE   156,584 0 0
REGENERON PHARMACEUTICALS COM 75886F107 142,757 228,895 SH   SOLE   228,895 0 0
HALLIBURTON CO COM 406216101 1,528 117,698 SH   SOLE   117,698 0 0
CLOVIS ONCOLOGY INC COM 189464100 8,764 1,298,364 SH   SOLE   1,298,364 0 0
JOHNSON & JOHNSON COM 478160104 5 32 SH   SOLE 1 0 0 32
MERCADOLIBRE INC COM 58733R102 27,528 27,924 SH   SOLE   27,924 0 0
BILIBILI INC SPONS ADS REP Z 090040106 8,407 181,500 SH   SOLE   181,500 0 0
DOW INC COM 260557103 2,770 67,950 SH   SOLE   67,950 0 0
ZTO EXPRESS CAYMAN INC SPONSORED ADS A 98980A105 19,633 534,799 SH   SOLE   534,799 0 0
IGM BIOSCIENCES INC COM 449585108 9,955 136,360 SH   SOLE   136,360 0 0
CONOCOPHILLIPS COM 20825C104 4,854 115,510 SH   SOLE   115,510 0 0
AMAZON COM INC COM 023135106 3 1 SH   SOLE 1 0 0 1
MASIMO CORP COM 574795100 2,052 9,000 SH   SOLE   9,000 0 0
CANON INC SPONSORED ADR 138006309 1 50 SH   SOLE 1 0 0 50
BADGER METER INC COM 056525108 1,131 17,973 SH   SOLE   17,973 0 0
BALLARD PWR SYS INC NEW COM 058586108 1,826 118,545 SH   SOLE   118,545 0 0
ENPHASE ENERGY INC COM 29355A107 7,260 152,614 SH   SOLE   152,614 0 0
TEXAS INSTRS INC COM 882508104 27,753 218,566 SH   SOLE   218,566 0 0
AKERS BIOSCIENCES INC COM 00973E409 126 36,146 SH   SOLE   36,146 0 0
ANSYS INC COM 03662Q105 2 8 SH   SOLE 1 0 0 8
E TRADE FINANCIAL CORP COM NEW 269246401 1 28 SH   SOLE 1 0 0 28
BOSTON PPTYS LTD PARTNERSHIP COM 101121101 5,107 56,499 SH   SOLE   56,499 0 0
ECOLAB INC COM 278865100 19,323 97,120 SH   SOLE   97,120 0 0
VULCAN MATLS CO COM 929160109 1 10 SH   SOLE 1 0 0 10
CENTRAL EUROPEAN MEDIA ENTRP CL A NEW G20045202 5,134 1,450,357 SH   SOLE   1,450,357 0 0
INTEL CORP COM 458140100 4 74 SH   SOLE 1 0 0 74
OPEN TEXT CORP COM 683715106 1,200 965 PRN   SOLE   965 0 0
GENUINE PARTS CO COM 372460105 798 9,172 SH   SOLE   9,172 0 0
MITSUBISHI UFJ FINL GROUP IN SPONSORED ADS 606822104 761 193,625 SH   SOLE   193,625 0 0
LKQ CORP COM 501889208 672 25,665 SH   SOLE   25,665 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 34,121 1,343,269 SH   SOLE   1,343,269 0 0
REGIONS FINANCIAL CORP NEW COM 7591EP100 3,521 316,594 SH   SOLE   316,594 0 0
SOUTHERN COPPER CORP COM 84265V105 20,427 513,600 SH   SOLE   513,600 0 0
PUBLIC STORAGE COM 74460D109 2,039 10,627 SH   SOLE   10,627 0 0
BIOMARIN PHARMACEUTICAL INC NOTE 1.500%10/1 09061GAF8 6,225 4,700 PRN   SOLE   4,700 0 0
JONES LANG LASALLE INC COM 48020Q107 5,472 52,883 SH   SOLE   52,883 0 0
YUM BRANDS INC COM 988498101 1,544 17,759 SH   SOLE   17,759 0 0
NEOGENOMICS INC COM NEW 64049M209 17,413 562,033 SH   SOLE   562,033 0 0
HP INC COM 40434L105 1 59 SH   SOLE 1 0 0 59
FIVE PRIME THERAPEUTICS INC COM 33830X104 3,063 502,139 SH   SOLE   502,139 0 0
CGI INC CL A SUB VTG 12532H104 373 5,939 SH   SOLE   5,939 0 0
PFIZER INC COM 717081103 5,460 166,968 SH   SOLE   166,968 0 0
SEATTLE GENETICS INC COM 812578102 3 16 SH   SOLE 1 0 0 16
MORGAN STANLEY COM NEW 617446448 17,157 355,210 SH   SOLE   355,210 0 0
COSTCO WHSL CORP NEW COM 22160K105 9,257 30,528 SH   SOLE   30,528 0 0
FORTUNE BRANDS HOME & SEC IN COM 34964C106 309 4,841 SH   SOLE   4,841 0 0
TPI COMPOSITES INC COM 87266J104 739 31,631 SH   SOLE   31,631 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 1,164 9,753 SH   SOLE   9,753 0 0
ATMOS ENERGY CORP COM 049560105 3,696 37,115 SH   SOLE   37,115 0 0
SPLUNK INC NOTE 0.500% 9/1 848637AC8 5,381 3,860 PRN   SOLE   3,860 0 0
ALTERYX INC COM CL A 02156B103 463 2,820 SH   SOLE   2,820 0 0
ETSY INC COM 29786A106 1,605 15,110 SH   SOLE   15,110 0 0
FOX CORP CL A COM 35137L105 253 9,425 SH   SOLE   9,425 0 0
WEYERHAEUSER CO MTN BE COM NEW 962166104 1,202 53,493 SH   SOLE   53,493 0 0
ROPER TECHNOLOGIES INC COM 776696106 5,503 14,174 SH   SOLE   14,174 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 3,931 382,013 SH   SOLE   382,013 0 0
EVERSOURCE ENERGY COM 30040W108 7,627 91,589 SH   SOLE   91,589 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 3 54 SH   SOLE 1 0 0 54
WELLS FARGO CO NEW COM 949746101 6,876 268,574 SH   SOLE   268,574 0 0
ALEXANDRIA REAL ESTATE EQ IN COM 015271109 1,467 9,041 SH   SOLE   9,041 0 0
CRH PLC ADR 12626K203 2 66 SH   SOLE 1 0 0 66
GENMAB A/S SPONSORED ADS 372303206 4,958 146,290 SH   SOLE   146,290 0 0
CAPITAL ONE FINL CORP COM 14040H105 3,878 61,953 SH   SOLE   61,953 0 0
SANGAMO THERAPEUTICS INC COM 800677106 3,315 370,000 SH   SOLE   370,000 0 0
KROGER CO COM 501044101 2,552 75,384 SH   SOLE   75,384 0 0
CARMAX INC COM 143130102 760 8,490 SH   SOLE   8,490 0 0
HEICO CORP NEW CL A 422806208 635 7,822 SH   SOLE   7,822 0 0
MOTOROLA SOLUTIONS INC COM NEW 620076307 4,226 30,155 SH   SOLE   30,155 0 0
INTL PAPER CO COM 460146103 2,472 70,213 SH   SOLE   70,213 0 0
INSMED INC COM PAR $.01 457669307 8,042 292,000 SH   SOLE   292,000 0 0
KEYSIGHT TECHNOLOGIES INC COM 49338L103 10,009 99,306 SH   SOLE   99,306 0 0
FLIR SYS INC COM 302445101 421 10,385 SH   SOLE   10,385 0 0
NIKE INC CL B 654106103 53,958 550,285 SH   SOLE   550,285 0 0
WASTE MGMT INC DEL COM 94106L109 50,231 474,262 SH   SOLE   474,262 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 11,859 394,629 SH   SOLE   394,629 0 0
HERSHEY CO COM 427866108 3 22 SH   SOLE 1 0 0 22
MARATHON PETE CORP COM 56585A102 1,532 40,983 SH   SOLE   40,983 0 0
XILINX INC COM 983919101 1,604 16,300 SH   SOLE   16,300 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 6,485 93,837 SH   SOLE   93,837 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 14,722 119,962 SH   SOLE   119,962 0 0
VERIZON COMMUNICATIONS INC COM 92343V104 32,171 583,515 SH   SOLE   583,515 0 0
KINDER MORGAN INC DEL COM 49456B101 8,157 537,712 SH   SOLE   537,712 0 0
S&P GLOBAL INC COM 78409V104 44,040 133,658 SH   SOLE   133,658 0 0
MODERNA INC COM 60770K107 18,642 285,834 SH   SOLE   285,834 0 0
CROWN CASTLE INTL CORP NEW COM 22822V101 12,674 75,733 SH   SOLE   75,733 0 0
BEIGENE LTD SPONSORED ADR 07725L102 2 9 SH   SOLE 1 0 0 9
MACQUARIE INFRASTRUCTURE COR NOTE 2.000%10/0 55608BAB1 177 200,000 PRN   SOLE   200,000 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 20,274 113,571 SH   SOLE   113,571 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 3,462 35,000 SH   SOLE   35,000 0 0
WATERS CORP COM 941848103 1,437 7,963 SH   SOLE   7,963 0 0
APPLIED MATLS INC COM 038222105 36,857 609,686 SH   SOLE   609,686 0 0
ROYAL BK CDA COM 780087102 4,634 68,512 SH   SOLE   68,512 0 0
BIONTECH SE SPONSORED ADS 09075V102 1 15 SH   SOLE 1 0 0 15
CITRIX SYS INC COM 177376100 14,866 100,501 SH   SOLE   100,501 0 0
SERVICENOW INC COM 81762P102 5,934 14,650 SH   SOLE   14,650 0 0
DOCUSIGN INC COM 256163106 2,085 12,109 SH   SOLE   12,109 0 0
ARISTA NETWORKS INC COM 040413106 1 5 SH   SOLE 1 0 0 5
REPUBLIC SVCS INC COM 760759100 3 33 SH   SOLE 1 0 0 33
EDISON INTL COM 281020107 1,722 31,708 SH   SOLE   31,708 0 0
TERADYNE INC COM 880770102 365 4,313 SH   SOLE   4,313 0 0
RIO TINTO PLC SPONSORED ADR 767204100 1 25 SH   SOLE 1 0 0 25
STARBUCKS CORP COM 855244109 19,555 265,723 SH   SOLE   265,723 0 0
T-MOBILE US INC RIGHT 07/27/2020 872590112 5 29,258 SH   SOLE   29,258 0 0
TRIMBLE INC COM 896239100 3 62 SH   SOLE 1 0 0 62
AMERICAN EXPRESS CO COM 025816109 1 14 SH   SOLE 1 0 0 14
WP CAREY INC COM 92936U109 882 13,044 SH   SOLE   13,044 0 0
TWILIO INC CL A 90138F102 2,206 10,054 SH   SOLE   10,054 0 0
BLUEBIRD BIO INC COM 09609G100 25,475 417,332 SH   SOLE   417,332 0 0
PPG INDS INC COM 693506107 2,086 19,664 SH   SOLE   19,664 0 0
EXACT SCIENCES CORP NOTE 0.375% 3/1 30063PAB1 468 450 PRN   SOLE   450 0 0
EOG RES INC COM 26875P101 3,559 70,257 SH   SOLE   70,257 0 0
MOMO INC NOTE 1.250% 7/0 60879BAB3 390 500 PRN   SOLE   500 0 0
PINTEREST INC CL A 72352L106 419 18,905 SH   SOLE   18,905 0 0
YUM CHINA HLDGS INC COM 98850P109 4,049 84,220 SH   SOLE   84,220 0 0
SUN LIFE FINANCIAL INC. COM 866796105 1,890 51,599 SH   SOLE   51,599 0 0
VERISIGN INC COM 92343E102 1,611 7,791 SH   SOLE   7,791 0 0
XYLEM INC COM 98419M100 2 36 SH   SOLE 1 0 0 36
F5 NETWORKS INC COM 315616102 2,853 20,457 SH   SOLE   20,457 0 0
GAP INC COM 364760108 202 15,989 SH   SOLE   15,989 0 0
PACKAGING CORP AMER COM 695156109 887 8,886 SH   SOLE   8,886 0 0
CANADIAN PAC RY LTD COM 13645T100 1,065 4,201 SH   SOLE   4,201 0 0
ONEOK INC NEW COM 682680103 3,495 3,500 PRN   SOLE   3,500 0 0
NVIDIA CORPORATION COM 67066G104 56,203 147,930 SH   SOLE   147,930 0 0
FASTENAL CO COM 311900104 1,716 40,063 SH   SOLE   40,063 0 0
WASTE CONNECTIONS INC COM 94106B101 10,486 111,797 SH   SOLE   111,797 0 0
CLOVIS ONCOLOGY INC COM 189464100 1 86 SH   SOLE 1 0 0 86
SYNOPSYS INC COM 871607107 17,461 89,541 SH   SOLE   89,541 0 0
AMERIPRISE FINL INC COM 03076C106 1 9 SH   SOLE 1 0 0 9
PACCAR INC COM 693718108 2,783 37,185 SH   SOLE   37,185 0 0
TELADOC HEALTH INC COM 87918A105 1,726 9,042 SH   SOLE   9,042 0 0
MOHAWK INDS INC COM 608190104 309 3,039 SH   SOLE   3,039 0 0
LAM RESEARCH CORP COM 512807108 10,093 31,203 SH   SOLE   31,203 0 0
REALTY INCOME CORP COM 756109104 1,311 22,037 SH   SOLE   22,037 0 0
IDEXX LABS INC COM 45168D104 8,325 25,214 SH   SOLE   25,214 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 15,377 238,067 SH   SOLE   238,067 0 0
ARCHER DANIELS MIDLAND CO COM 039483102 1,504 37,704 SH   SOLE   37,704 0 0
IMMUNOMEDICS INC COM 452907108 39,999 1,128,582 SH   SOLE   1,128,582 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 12,749 2,808,500 SH Put SOLE   2,808,500 0 0
CITIZENS FINANCIAL GROUP INC COM 174610105 1,452 57,510 SH   SOLE   57,510 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 16,695 1,229,346 SH   SOLE   1,229,346 0 0
PRINCIPAL FINANCIAL GROUP IN COM 74251V102 6,911 166,365 SH   SOLE   166,365 0 0
DIGITAL TURBINE INC COM NEW 25400W102 343 27,300 SH   SOLE   27,300 0 0
MOLSON COORS BEVERAGE CO CL B 60871R209 652 18,989 SH   SOLE   18,989 0 0
FIFTH THIRD BANCORP COM 316773100 1,889 97,991 SH   SOLE   97,991 0 0
UNIVERSAL HLTH SVCS INC CL B 913903100 2,750 29,601 SH   SOLE   29,601 0 0
INTERNATIONAL BUSINESS MACHS COM 459200101 2 15 SH   SOLE 1 0 0 15
FISERV INC COM 337738108 3,267 33,468 SH   SOLE   33,468 0 0
FIRST REP BK SAN FRANCISCO C COM 33616C100 6,560 61,893 SH   SOLE   61,893 0 0
ESSEX PPTY TR INC COM 297178105 1,184 5,167 SH   SOLE   5,167 0 0
CINCINNATI FINL CORP COM 172062101 730 11,407 SH   SOLE   11,407 0 0
BALL CORP COM 058498106 18,883 271,727 SH   SOLE   271,727 0 0
HOLOGIC INC COM 436440101 38,359 672,928 SH   SOLE   672,928 0 0
NEXTERA ENERGY INC COM 65339F101 32,288 134,432 SH   SOLE   134,432 0 0
MEDTRONIC PLC SHS G5960L103 2 26 SH   SOLE 1 0 0 26
ROGERS COMMUNICATIONS INC CL B 775109200 658 16,431 SH   SOLE   16,431 0 0
EQUIFAX INC COM 294429105 1,263 7,348 SH   SOLE   7,348 0 0
CISCO SYS INC COM 17275R102 53,317 1,143,099 SH   SOLE   1,143,099 0 0
D R HORTON INC COM 23331A109 5,946 107,225 SH   SOLE   107,225 0 0
TECH DATA CORP COM 878237106 9,931 68,489 SH   SOLE   68,489 0 0
NEOGENOMICS INC COM NEW 64049M209 2 65 SH   SOLE 1 0 0 65
PIERIS PHARMACEUTICALS INC COM 720795103 7,271 2,345,326 SH   SOLE   2,345,326 0 0
NUANCE COMMUNICATIONS INC COM 67020Y100 3,973 157,000 SH   SOLE   157,000 0 0
CF INDS HLDGS INC COM 125269100 1,497 53,203 SH   SOLE   53,203 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 565 20,000 SH   SOLE   20,000 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 0 8 SH   SOLE 1 0 0 8
LIBERTY BROADBAND CORP COM SER C 530307305 810 6,531 SH   SOLE   6,531 0 0
PALO ALTO NETWORKS INC NOTE 0.750% 7/0 697435AD7 4,577 4,250 PRN   SOLE   4,250 0 0
FREEPORT-MCMORAN INC CL B 35671D857 4,955 428,258 SH   SOLE   428,258 0 0
ROBERT HALF INTL INC COM 770323103 3,780 71,551 SH   SOLE   71,551 0 0
ESSENTIAL UTILS INC COM 29670G102 1,386 32,817 SH   SOLE   32,817 0 0
QORVO INC COM 74736K101 654 5,914 SH   SOLE   5,914 0 0
WALMART INC COM 931142103 2,576 21,502 SH   SOLE   21,502 0 0
PARKER HANNIFIN CORP COM 701094104 5,116 27,916 SH   SOLE   27,916 0 0
ALLSTATE CORP COM 020002101 33,495 345,334 SH   SOLE   345,334 0 0
BANK MONTREAL QUE COM 063671101 1,218 22,950 SH   SOLE   22,950 0 0
MCKESSON CORP COM 58155Q103 5,861 38,202 SH   SOLE   38,202 0 0
HD SUPPLY HLDGS INC COM 40416M105 731 21,089 SH   SOLE   21,089 0 0
INTERNATIONAL FLAVORS&FRAGRA COM 459506101 812 6,634 SH   SOLE   6,634 0 0
WORKDAY INC CL A 98138H101 2,322 12,395 SH   SOLE   12,395 0 0
SKYWORKS SOLUTIONS INC COM 83088M102 1,424 11,136 SH   SOLE   11,136 0 0
MESA LABS INC COM 59064R109 1,778 8,200 SH   SOLE   8,200 0 0
LAUDER ESTEE COS INC CL A 518439104 20,412 108,177 SH   SOLE   108,177 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 11,516 253,306 SH   SOLE   253,306 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 2,812 20,145 SH   SOLE   20,145 0 0
ANGIODYNAMICS INC COM 03475V101 1,271 125,000 SH   SOLE   125,000 0 0
COLGATE PALMOLIVE CO COM 194162103 1 16 SH   SOLE 1 0 0 16
HSBC HLDGS PLC SPON ADR NEW 404280406 1 41 SH   SOLE 1 0 0 41
REVANCE THERAPEUTICS INC COM 761330109 1,099 45,000 SH   SOLE   45,000 0 0
WILLIAMS COS INC COM 969457100 6,795 357,238 SH   SOLE   357,238 0 0
APOLLO GLOBAL MGMT INC COM CL A 03768E105 1,422 28,475 SH   SOLE   28,475 0 0
GILDAN ACTIVEWEAR INC COM 375916103 800 51,804 SH   SOLE   51,804 0 0
BROOKFIELD ASSET MGMT INC CL A LTD VT SH 112585104 1,370 42,527 SH   SOLE   42,527 0 0
NEKTAR THERAPEUTICS COM 640268108 7,317 315,929 SH   SOLE   315,929 0 0
MYLAN NV SHS EURO N59465109 1 50 SH   SOLE 1 0 0 50
ETSY INC COM 29786A106 2,660 2,450 PRN   SOLE   2,450 0 0
ENTERGY CORP NEW COM 29364G103 2,591 27,614 SH   SOLE   27,614 0 0
NORTHERN TR CORP COM 665859104 1,400 17,651 SH   SOLE   17,651 0 0
XP INC CL A G98239109 17,351 413,000 SH   SOLE   413,000 0 0
AVALONBAY CMNTYS INC COM 053484101 1,883 12,176 SH   SOLE   12,176 0 0
COMERICA INC COM 200340107 1,239 32,527 SH   SOLE   32,527 0 0
TETRA TECH INC NEW COM 88162G103 2 19 SH   SOLE 1 0 0 19
COHERUS BIOSCIENCES INC COM 19249H103 1 68 SH   SOLE 1 0 0 68
QUEST DIAGNOSTICS INC COM 74834L100 4,654 40,833 SH   SOLE   40,833 0 0
ABBVIE INC COM 00287Y109 65,152 663,570 SH   SOLE   663,570 0 0
BIO-TECHNE CORP COM 09073M104 29,388 111,283 SH   SOLE   111,283 0 0
NUCOR CORP COM 670346105 1,309 31,604 SH   SOLE   31,604 0 0
STEEL DYNAMICS INC COM 858119100 677 25,958 SH   SOLE   25,958 0 0
GENERAL MTRS CO COM 37045V100 2,678 105,833 SH   SOLE   105,833 0 0
CHIASMA INC COM 16706W102 126 23,500 SH   SOLE   23,500 0 0
ETF MANAGERS TR PRIME CYBR SCRTY 26924G201 1,675 37,650 SH   SOLE   37,650 0 0
HARTFORD FINL SVCS GROUP INC COM 416515104 4,422 114,716 SH   SOLE   114,716 0 0
COCA COLA CO COM 191216100 25,163 563,152 SH   SOLE   563,152 0 0
PLANET FITNESS INC CL A 72703H101 4,211 69,524 SH   SOLE   69,524 0 0
NEXTERA ENERGY PARTNERS LP COM UNIT PART IN 65341B106 1 27 SH   SOLE 1 0 0 27
MYOVANT SCIENCES LTD COM G637AM102 4,565 221,377 SH   SOLE   221,377 0 0
COGNEX CORP COM 192422103 590 9,872 SH   SOLE   9,872 0 0
TELEFONICA S A SPONSORED ADR 879382208 2 514 SH   SOLE 1 0 0 514
BIO-TECHNE CORP COM 09073M104 3 12 SH   SOLE 1 0 0 12
MERSANA THERAPEUTICS INC COM 59045L106 1 35 SH   SOLE 1 0 0 35
TELEFLEX INCORPORATED COM 879369106 830 2,280 SH   SOLE   2,280 0 0
SVB FINANCIAL GROUP COM 78486Q101 684 3,173 SH   SOLE   3,173 0 0
HUNTINGTON BANCSHARES INC COM 446150104 1,665 184,230 SH   SOLE   184,230 0 0
MOBILE MINI INC COM 60740F105 1,737 58,778 SH   SOLE   58,778 0 0
ACTIVISION BLIZZARD INC COM 00507V109 27,555 363,023 SH   SOLE   363,023 0 0
ONEOK INC NEW COM 682680103 4,409 132,714 SH   SOLE   132,714 0 0
JD.COM INC SPON ADR CL A 47215P106 44,801 744,410 SH   SOLE   744,410 0 0
HOLLYFRONTIER CORP COM 436106108 646 22,139 SH   SOLE   22,139 0 0
KURA ONCOLOGY INC COM 50127T109 3,907 239,676 SH   SOLE   239,676 0 0
CITRIX SYS INC COM 177376100 1 10 SH   SOLE 1 0 0 10
HOWMET AEROSPACE INC COM 443201108 527 33,235 SH   SOLE   33,235 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 28,114 190,079 SH   SOLE   190,079 0 0
PAN AMERN SILVER CORP COM 697900108 10,941 360,000 SH   SOLE   360,000 0 0
CADENCE DESIGN SYSTEM INC COM 127387108 19,894 207,304 SH   SOLE   207,304 0 0
PAGSEGURO DIGITAL LTD COM CL A G68707101 401 11,350 SH   SOLE   11,350 0 0
BK OF AMERICA CORP COM 060505104 20,030 843,268 SH   SOLE   843,268 0 0
MCDONALDS CORP COM 580135101 1 5 SH   SOLE 1 0 0 5
VARIAN MED SYS INC COM 92220P105 3 24 SH   SOLE 1 0 0 24
LABORATORY CORP AMER HLDGS COM NEW 50540R409 3 17 SH   SOLE 1 0 0 17
GUARDANT HEALTH INC COM 40131M109 6,375 78,580 SH   SOLE   78,580 0 0
TRUIST FINL CORP COM 89832Q109 3,305 88,006 SH   SOLE   88,006 0 0
ZIONS BANCORPORATION N A COM 989701107 8,677 255,203 SH   SOLE   255,203 0 0
BAIDU INC SPON ADR REP A 056752108 4,799 40,028 SH   SOLE   40,028 0 0
REGENCY CTRS CORP COM 758849103 517 11,270 SH   SOLE   11,270 0 0
PEPSICO INC COM 713448108 5 37 SH   SOLE 1 0 0 37
CHINA MOBILE LIMITED SPONSORED ADR 16941M109 1,888 56,126 SH   SOLE   56,126 0 0
WP CAREY INC COM 92936U109 733 500 PRN   SOLE   500 0 0
CAPITAL ONE FINL CORP COM 14040H105 2 24 SH   SOLE 1 0 0 24
CHURCH & DWIGHT INC COM 171340102 1 13 SH   SOLE 1 0 0 13
COLGATE PALMOLIVE CO COM 194162103 8,885 121,280 SH   SOLE   121,280 0 0
BIONTECH SE SPONSORED ADS 09075V102 27,385 410,298 SH   SOLE   410,298 0 0
TANGER FACTORY OUTLET CTRS I COM 875465106 100 14,000 SH   SOLE   14,000 0 0
ADVANCED DISP SVCS INC DEL COM 00790X101 31,612 1,047,755 SH   SOLE   1,047,755 0 0
VMWARE INC CL A COM 928563402 2 14 SH   SOLE 1 0 0 14
VIAVI SOLUTIONS INC NOTE 1.000% 3/0 925550AB1 1,814 1,570 PRN   SOLE   1,570 0 0
NATIONAL RETAIL PROPERTIES I COM 637417106 629 17,736 SH   SOLE   17,736 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 1 17 SH   SOLE 1 0 0 17
FOX CORP CL B COM 35137L204 771 28,735 SH   SOLE   28,735 0 0
MSCI INC COM 55354G100 1,771 5,305 SH   SOLE   5,305 0 0
VMWARE INC CL A COM 928563402 28,985 187,159 SH   SOLE   187,159 0 0
OMNICOM GROUP INC COM 681919106 1 21 SH   SOLE 1 0 0 21
TRIP COM GROUP LTD ADS 89677Q107 934 36,020 SH   SOLE   36,020 0 0
MYOKARDIA INC COM 62857M105 13,334 138,000 SH   SOLE   138,000 0 0
ALPHABET INC CAP STK CL C 02079K107 64,759 45,809 SH   SOLE   45,809 0 0
AVERY DENNISON CORP COM 053611109 2,464 21,598 SH   SOLE   21,598 0 0
MONDELEZ INTL INC CL A 609207105 3 59 SH   SOLE 1 0 0 59
VERTEX PHARMACEUTICALS INC COM 92532F100 2 6 SH   SOLE 1 0 0 6
CLOROX CO DEL COM 189054109 2,474 11,277 SH   SOLE   11,277 0 0
SHAW COMMUNICATIONS INC CL B CONV 82028K200 2,273 139,803 SH   SOLE   139,803 0 0
FORTIVE CORP NOTE 0.875% 2/1 34959JAK4 6,973 7,100 PRN   SOLE   7,100 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 1 23 SH   SOLE 1 0 0 23
CEVA INC COM 157210105 11,672 311,894 SH   SOLE   311,894 0 0
ENBRIDGE INC COM 29250N105 1,246 41,092 SH   SOLE   41,092 0 0
ORACLE CORP COM 68389X105 3 49 SH   SOLE 1 0 0 49
MOSAIC CO NEW COM 61945C103 1,836 146,763 SH   SOLE   146,763 0 0
AGNICO EAGLE MINES LTD COM 008474108 357 5,593 SH   SOLE   5,593 0 0
SOCIEDAD QUIMICA Y MINERA DE SPON ADR SER B 833635105 17,478 670,400 SH   SOLE   670,400 0 0
IMMUNOMEDICS INC COM 452907108 2 50 SH   SOLE 1 0 0 50
VONAGE HLDGS CORP COM 92886T201 915 5,614,000 SH Put SOLE   5,614,000 0 0
JOHNSON & JOHNSON COM 478160104 57,710 410,349 SH   SOLE   410,349 0 0
IONIS PHARMACEUTICALS INC COM 462222100 14,959 253,700 SH   SOLE   253,700 0 0
FORTINET INC COM 34959E109 11,529 83,983 SH   SOLE   83,983 0 0
BROADRIDGE FINL SOLUTIONS IN COM 11133T103 2,167 17,173 SH   SOLE   17,173 0 0
IQIYI INC NOTE 2.000% 4/0 46267XAD0 1,324 201,125 PRN   SOLE   201,125 0 0
FRANCO NEV CORP COM 351858105 685 4,917 SH   SOLE   4,917 0 0
MID-AMER APT CMNTYS INC COM 59522J103 861 7,507 SH   SOLE   7,507 0 0
CHURCH & DWIGHT INC COM 171340102 11,723 151,653 SH   SOLE   151,653 0 0
CATERPILLAR INC DEL COM 149123101 7,083 55,987 SH   SOLE   55,987 0 0
SMUCKER J M CO COM NEW 832696405 1,110 10,488 SH   SOLE   10,488 0 0
ROCKWELL AUTOMATION INC COM 773903109 2 10 SH   SOLE 1 0 0 10
AKAMAI TECHNOLOGIES INC COM 00971T101 5,356 50,014 SH   SOLE   50,014 0 0
PTC THERAPEUTICS INC COM 69366J200 39,272 773,960 SH   SOLE   773,960 0 0
ULTA BEAUTY INC COM 90384S303 523 2,569 SH   SOLE   2,569 0 0
NORFOLK SOUTHERN CORP COM 655844108 3,867 22,026 SH   SOLE   22,026 0 0
ROCKWELL AUTOMATION INC COM 773903109 41,967 197,020 SH   SOLE   197,020 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 12,634 172,799 SH   SOLE   172,799 0 0
GENERAL MLS INC COM 370334104 11,167 181,135 SH   SOLE   181,135 0 0
UNIVERSAL DISPLAY CORP COM 91347P105 2 12 SH   SOLE 1 0 0 12
CSX CORP COM 126408103 1 13 SH   SOLE 1 0 0 13
BIOGEN INC COM 09062X103 91,217 340,919 SH   SOLE   340,919 0 0
INTEL CORP COM 458140100 54,571 912,064 SH   SOLE   912,064 0 0
BRISTOL-MYERS SQUIBB CO RIGHT 99/99/9999 110122157 697 194,693 SH   SOLE   194,693 0 0
TELEDYNE TECHNOLOGIES INC COM 879360105 881 2,834 SH   SOLE   2,834 0 0
HUMANA INC COM 444859102 16,598 42,805 SH   SOLE   42,805 0 0
CBRE GROUP INC CL A 12504L109 16,272 359,831 SH   SOLE   359,831 0 0
FRANKLIN RESOURCES INC COM 354613101 930 44,331 SH   SOLE   44,331 0 0
METLIFE INC COM 59156R108 9,293 254,450 SH   SOLE   254,450 0 0
TG THERAPEUTICS INC COM 88322Q108 1 70 SH   SOLE 1 0 0 70
SHERWIN WILLIAMS CO COM 824348106 10,131 17,532 SH   SOLE   17,532 0 0
CATALENT INC COM 148806102 685 9,344 SH   SOLE   9,344 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 11,618 102,584 SH   SOLE   102,584 0 0
TWITTER INC NOTE 1.000% 9/1 90184LAD4 5,117 205,000 PRN   SOLE   205,000 0 0
ADVANCED MICRO DEVICES INC COM 007903107 15,927 302,722 SH   SOLE   302,722 0 0
LENNAR CORP CL A 526057104 862 13,989 SH   SOLE   13,989 0 0
ALTERYX INC COM CL A 02156B103 2,958 2,765 PRN   SOLE   2,765 0 0
ANTHEM INC COM 036752103 10,485 39,869 SH   SOLE   39,869 0 0
LINCOLN NATL CORP IND COM 534187109 2,968 80,678 SH   SOLE   80,678 0 0
DUKE REALTY CORP COM NEW 264411505 266 7,517 SH   SOLE   7,517 0 0
FEDEX CORP COM 31428X106 3,077 21,940 SH   SOLE   21,940 0 0
PEOPLES UNITED FINANCIAL INC COM 712704105 931 80,470 SH   SOLE   80,470 0 0
ICICI BANK LIMITED ADR 45104G104 3,015 324,552 SH   SOLE   324,552 0 0
GUARDANT HEALTH INC COM 40131M109 1 7 SH   SOLE 1 0 0 7
CARDINAL HEALTH INC COM 14149Y108 5,589 107,076 SH   SOLE   107,076 0 0
ITAU UNIBANCO HLDG S A SPON ADR REP PFD 465562106 789 168,193 SH   SOLE   168,193 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 26,726 996,827 SH   SOLE   996,827 0 0
ONE GAS INC COM 68235P108 996 12,930 SH   SOLE   12,930 0 0
TETRA TECH INC NEW COM 88162G103 7,801 98,593 SH   SOLE   98,593 0 0
KIMBERLY CLARK CORP COM 494368103 2 16 SH   SOLE 1 0 0 16
CANADIAN NAT RES LTD COM 136385101 456 26,368 SH   SOLE   26,368 0 0
MARATHON OIL CORP COM 565849106 248 40,556 SH   SOLE   40,556 0 0
KROGER CO COM 501044101 2 66 SH   SOLE 1 0 0 66
BIOLIFE SOLUTIONS INC COM NEW 09062W204 1,243 76,000 SH   SOLE   76,000 0 0
SYNCHRONY FINANCIAL COM 87165B103 1,273 57,422 SH   SOLE   57,422 0 0
EQUITY LIFESTYLE PPTYS INC COM 29472R108 698 11,175 SH   SOLE   11,175 0 0
PEMBINA PIPELINE CORP COM 706327103 4,859 194,969 SH   SOLE   194,969 0 0
AMERICAN TOWER CORP NEW COM 03027X100 17,946 69,411 SH   SOLE   69,411 0 0
GALLAGHER ARTHUR J & CO COM 363576109 986 10,118 SH   SOLE   10,118 0 0
TIFFANY & CO NEW COM 886547108 23,601 193,534 SH   SOLE   193,534 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 63,317 564,099 SH   SOLE   564,099 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 7,275 54,249 SH   SOLE   54,249 0 0
PEPSICO INC COM 713448108 52,413 396,269 SH   SOLE   396,269 0 0
GENMAB A/S SPONSORED ADS 372303206 5 140 SH   SOLE 1 0 0 140
ADVANCED DRAIN SYS INC DEL COM 00790R104 2 45 SH   SOLE 1 0 0 45
CIGNA CORP NEW COM 125523100 1 6 SH   SOLE 1 0 0 6
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 63,465 1,117,891 SH   SOLE   1,117,891 0 0
NATIONAL FUEL GAS CO N J COM 636180101 419 9,981 SH   SOLE   9,981 0 0
EQUITABLE HLDGS INC COM 29452E101 6,144 318,494 SH   SOLE   318,494 0 0
BIO RAD LABS INC CL A 090572207 3 7 SH   SOLE 1 0 0 7
MACROGENICS INC COM 556099109 13,079 468,417 SH   SOLE   468,417 0 0
THOMSON REUTERS CORP. COM NEW 884903709 979 14,453 SH   SOLE   14,453 0 0
CORNING INC COM 219350105 1,572 60,688 SH   SOLE   60,688 0 0
REINSURANCE GRP OF AMERICA I COM NEW 759351604 3,913 49,883 SH   SOLE   49,883 0 0
ADOBE INC COM 00724F101 2 5 SH   SOLE 1 0 0 5
C H ROBINSON WORLDWIDE INC COM NEW 12541W209 1 11 SH   SOLE 1 0 0 11
ESPERION THERAPEUTICS INC NE COM 29664W105 5,993 116,804 SH   SOLE   116,804 0 0
IHS MARKIT LTD SHS G47567105 2,392 31,687 SH   SOLE   31,687 0 0
BANCO SANTANDER BRASIL S A ADS REP 1 UNIT 05967A107 62 11,920 SH   SOLE   11,920 0 0
SHINHAN FINANCIAL GROUP CO L SPN ADR RESTRD 824596100 232 9,648 SH   SOLE   9,648 0 0
HOST HOTELS & RESORTS INC COM 44107P104 2,055 190,465 SH   SOLE   190,465 0 0
AKAMAI TECHNOLOGIES INC NOTE 0.125% 5/0 00971TAJ0 8,106 6,500 PRN   SOLE   6,500 0 0
APREA THERAPEUTICS INC COM 03836J102 5,072 130,774 SH   SOLE   130,774 0 0
EXTRA SPACE STORAGE INC COM 30225T102 627 6,788 SH   SOLE   6,788 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 687 85,000 SH   SOLE   85,000 0 0
ALIGN TECHNOLOGY INC COM 016255101 1,408 5,132 SH   SOLE   5,132 0 0
MARSH & MCLENNAN COS INC COM 571748102 5,166 48,108 SH   SOLE   48,108 0 0
NIKE INC CL B 654106103 1 14 SH   SOLE 1 0 0 14
CONSTELLATION BRANDS INC CL A 21036P108 1,710 9,774 SH   SOLE   9,774 0 0
CEMEX SAB DE CV SPON ADR NEW 151290889 234 81,075 SH   SOLE   81,075 0 0
AMERISOURCEBERGEN CORP COM 03073E105 1 12 SH   SOLE 1 0 0 12
VARONIS SYS INC COM 922280102 21,855 246,999 SH   SOLE   246,999 0 0
SONY CORP SPONSORED ADR 835699307 1 17 SH   SOLE 1 0 0 17
EXCHANGE TRADED CONCEPTS TR EMQQ EM INTERN 301505889 683 14,620 SH   SOLE   14,620 0 0
HENRY JACK & ASSOC INC COM 426281101 660 3,587 SH   SOLE   3,587 0 0
ANNALY CAPITAL MANAGEMENT IN COM 035710409 756 115,311 SH   SOLE   115,311 0 0
AUTOMATIC DATA PROCESSING IN COM 053015103 27,637 185,615 SH   SOLE   185,615 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 1,478 1,500 PRN   SOLE   1,500 0 0
VARIAN MED SYS INC COM 92220P105 25,843 210,923 SH   SOLE   210,923 0 0
KEURIG DR PEPPER INC COM 49271V100 1 32 SH   SOLE 1 0 0 32
WASTE MGMT INC DEL COM 94106L109 8 73 SH   SOLE 1 0 0 73
SPLUNK INC COM 848637104 41,877 210,744 SH   SOLE   210,744 0 0
VONAGE HLDGS CORP NOTE 1.750% 6/0 92886TAJ1 185 200,000 PRN   SOLE   200,000 0 0
VALE S A SPONSORED ADS 91912E105 110 10,710 SH   SOLE   10,710 0 0
NETFLIX INC COM 64110L106 29,990 65,904 SH   SOLE   65,904 0 0
EQUINOR ASA SPONSORED ADR 29446M102 1 77 SH   SOLE 1 0 0 77
KEZAR LIFE SCIENCES INC COM 49372L100 3,108 600,000 SH   SOLE   600,000 0 0
ZEBRA TECHNOLOGIES CORPORATI CL A 989207105 1 4 SH   SOLE 1 0 0 4
QUALCOMM INC COM 747525103 34,479 378,004 SH   SOLE   378,004 0 0
AMPHENOL CORP NEW CL A 032095101 9,490 99,041 SH   SOLE   99,041 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 1 12 SH   SOLE 1 0 0 12
CENOVUS ENERGY INC COM 15135U109 86 18,527 SH   SOLE   18,527 0 0
BCE INC COM NEW 05534B760 2,744 66,006 SH   SOLE   66,006 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 13,871 321,146 SH   SOLE   321,146 0 0
ASE TECHNOLOGY HOLDING CO LT SPONSORED ADS 00215W100 82 18,156 SH   SOLE   18,156 0 0
ALTRIA GROUP INC COM 02209S103 341 8,700 SH   SOLE   8,700 0 0
ARCH CAP GROUP LTD ORD G0450A105 731 25,509 SH   SOLE   25,509 0 0
NEW ORIENTAL ED & TECHNOLOGY SPON ADR 647581107 26,319 202,087 SH   SOLE   202,087 0 0
HP INC COM 40434L105 7,179 411,849 SH   SOLE   411,849 0 0
HESS CORP COM 42809H107 1,303 25,158 SH   SOLE   25,158 0 0
KINROSS GOLD CORP COM 496902404 3,541 492,143 SH   SOLE   492,143 0 0
ASSURANT INC COM 04621X108 720 6,966 SH   SOLE   6,966 0 0
RESTAURANT BRANDS INTL INC COM 76131D103 5,174 95,364 SH   SOLE   95,364 0 0
EBAY INC. COM 278642103 15,153 288,895 SH   SOLE   288,895 0 0
WESTROCK CO COM 96145D105 489 17,310 SH   SOLE   17,310 0 0
CONCHO RES INC COM 20605P101 750 14,557 SH   SOLE   14,557 0 0
ATMOS ENERGY CORP COM 049560105 1 13 SH   SOLE 1 0 0 13
INTERCONTINENTAL EXCHANGE IN COM 45866F104 3,203 34,961 SH   SOLE   34,961 0 0
MONSTER BEVERAGE CORP NEW COM 61174X109 7,363 106,217 SH   SOLE   106,217 0 0
PHILLIPS 66 COM 718546104 2,497 34,728 SH   SOLE   34,728 0 0
SEATTLE GENETICS INC COM 812578102 66,425 390,903 SH   SOLE   390,903 0 0
SOUTHWEST AIRLS CO COM 844741108 6,236 182,439 SH   SOLE   182,439 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 11,585 239,000 SH   SOLE   239,000 0 0
BROOKFIELD RENEWABLE PARTNER PARTNERSHIP UNIT G16258108 1,023 1,000 PRN   SOLE   1,000 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 1 10 SH   SOLE 1 0 0 10
TE CONNECTIVITY LTD REG SHS H84989104 5 61 SH   SOLE 1 0 0 61
EL PASO ELEC CO COM NEW 283677854 14,715 219,615 SH   SOLE   219,615 0 0
HOLLYSYS AUTOMATION TCHNGY L SHS G45667105 11,857 891,448 SH   SOLE   891,448 0 0
SAGE THERAPEUTICS INC COM 78667J108 5,106 4,000 PRN   SOLE   4,000 0 0
PALO ALTO NETWORKS INC COM 697435105 1 5 SH   SOLE 1 0 0 5
LAUDER ESTEE COS INC CL A 518439104 1 6 SH   SOLE 1 0 0 6
ORMAT TECHNOLOGIES INC COM 686688102 1 16 SH   SOLE 1 0 0 16
VERIZON COMMUNICATIONS INC COM 92343V104 4 77 SH   SOLE 1 0 0 77
SL GREEN RLTY CORP COM 78440X101 3,067 62,219 SH   SOLE   62,219 0 0
FIBROGEN INC COM 31572Q808 8,670 213,900 SH   SOLE   213,900 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 20,797 757,616 SH   SOLE   757,616 0 0
S&P GLOBAL INC COM 78409V104 4 12 SH   SOLE 1 0 0 12
MONDELEZ INTL INC CL A 609207105 8,222 160,791 SH   SOLE   160,791 0 0
SEMPRA ENERGY COM 816851109 4,136 35,280 SH   SOLE   35,280 0 0
SAREPTA THERAPEUTICS INC COM 803607100 28,033 174,829 SH   SOLE   174,829 0 0
JUNIPER NETWORKS INC COM 48203R104 518 22,642 SH   SOLE   22,642 0 0
PUBLIC SVC ENTERPRISE GRP IN COM 744573106 2,360 47,995 SH   SOLE   47,995 0 0
KODIAK SCIENCES INC COM 50015M109 21,568 398,507 SH   SOLE   398,507 0 0
INGERSOLL RAND INC COM 45687V106 733 26,057 SH   SOLE   26,057 0 0
I MAB SPONSORED ADS 44975P103 977 32,624 SH   SOLE   32,624 0 0
BOSTON SCIENTIFIC CORP COM 101137107 2,853 81,267 SH   SOLE   81,267 0 0
OKTA INC CL A 679295105 1,409 7,037 SH   SOLE   7,037 0 0
V F CORP COM 918204108 6,022 98,807 SH   SOLE   98,807 0 0
CSX CORP COM 126408103 3,993 57,248 SH   SOLE   57,248 0 0
SCHLUMBERGER LTD COM 806857108 7,586 412,500 SH   SOLE   412,500 0 0
CONAGRA BRANDS INC COM 205887102 1,070 30,416 SH   SOLE   30,416 0 0
ERICSSON ADR B SEK 10 294821608 2 226 SH   SOLE 1 0 0 226
CUMMINS INC COM 231021106 2 12 SH   SOLE 1 0 0 12
IGM BIOSCIENCES INC COM 449585108 1 8 SH   SOLE 1 0 0 8
HOME DEPOT INC COM 437076102 35,740 142,664 SH   SOLE   142,664 0 0
NUTRIEN LTD COM 67077M108 604 18,869 SH   SOLE   18,869 0 0
HANNON ARMSTRONG SUST INFR C COM 41068X100 5,354 188,105 SH   SOLE   188,105 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 3 42 SH   SOLE 1 0 0 42
ALLOGENE THERAPEUTICS INC COM 019770106 2,908 67,919 SH   SOLE   67,919 0 0
NUCOR CORP COM 670346105 1 13 SH   SOLE 1 0 0 13
IMMUNOVANT INC COM 45258J102 3,409 140,000 SH   SOLE   140,000 0 0
DISNEY WALT CO COM DISNEY 254687106 65,545 587,740 SH   SOLE   587,740 0 0
KANSAS CITY SOUTHERN COM NEW 485170302 8,159 54,647 SH   SOLE   54,647 0 0
WELLTOWER INC COM 95040Q104 2,130 41,156 SH   SOLE   41,156 0 0
ANSYS INC COM 03662Q105 29,962 102,700 SH   SOLE   102,700 0 0
MOLINA HEALTHCARE INC COM 60855R100 469 2,636 SH   SOLE   2,636 0 0
DISCOVERY INC COM SER C 25470F302 885 45,954 SH   SOLE   45,954 0 0
NETEASE INC SPONSORED ADS 64110W102 20,001 46,580 SH   SOLE   46,580 0 0
MORPHOSYS AG SPONSORED ADS 617760202 8,446 266,684 SH   SOLE   266,684 0 0
HORIZON PHARMA INVT LTD NOTE 2.500% 3/1 44052TAB7 972 500 PRN   SOLE   500 0 0
DIAMONDBACK ENERGY INC COM 25278X109 677 16,191 SH   SOLE   16,191 0 0
MONGODB INC CL A 60937P106 699 3,086 SH   SOLE   3,086 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 1 40 SH   SOLE 1 0 0 40
AT&T INC COM 00206R102 29,688 982,019 SH   SOLE   982,019 0 0
PVH CORPORATION COM 693656100 4,811 100,129 SH   SOLE   100,129 0 0
SNAP INC CL A 83304A106 973 41,415 SH   SOLE   41,415 0 0
VIEWRAY INC COM 92672L107 0 107 SH   SOLE 1 0 0 107
Y-MABS THERAPEUTICS INC COM 984241109 1 18 SH   SOLE 1 0 0 18
ORMAT TECHNOLOGIES INC COM 686688102 5,590 88,036 SH   SOLE   88,036 0 0
BANCO BRADESCO S A SP ADR PFD NEW 059460303 1,438 377,462 SH   SOLE   377,462 0 0
DR REDDYS LABS LTD ADR 256135203 742 14,000 SH   SOLE   14,000 0 0
TORONTO DOMINION BK ONT COM NEW 891160509 5,594 125,740 SH   SOLE   125,740 0 0
TEAM INC NOTE 5.000% 8/0 878155AE0 131 200,000 PRN   SOLE   200,000 0 0
BROWN FORMAN CORP CL B 115637209 1,475 23,173 SH   SOLE   23,173 0 0
OTIS WORLDWIDE CORP COM 68902V107 1,706 29,994 SH   SOLE   29,994 0 0
BLACKROCK INC COM 09247X101 5,547 10,195 SH   SOLE   10,195 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 19,067 156,282 SH   SOLE   156,282 0 0
WESTERN DIGITAL CORP. COM 958102105 798 18,076 SH   SOLE   18,076 0 0
MASTERCARD INCORPORATED CL A 57636Q104 42,917 145,132 SH   SOLE   145,132 0 0
MORGAN STANLEY COM NEW 617446448 3 70 SH   SOLE 1 0 0 70
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 4,283 67,843 SH   SOLE   67,843 0 0
TECK RESOURCES LTD CL B 878742204 402 38,496 SH   SOLE   38,496 0 0
GRAINGER W W INC COM 384802104 2,433 7,743 SH   SOLE   7,743 0 0
ROSS STORES INC COM 778296103 1,081 1,000 PRN   SOLE   1,000 0 0
INCYTE CORP COM 45337C102 1 14 SH   SOLE 1 0 0 14
REGENERON PHARMACEUTICALS COM 75886F107 4 6 SH   SOLE 1 0 0 6
AMGEN INC COM 031162100 4 19 SH   SOLE 1 0 0 19
BLUEPRINT MEDICINES CORP COM 09627Y109 68,534 878,602 SH   SOLE   878,602 0 0
BEYOND MEAT INC COM 08862E109 820 6,121 SH   SOLE   6,121 0 0
EXXON MOBIL CORP COM 30231G102 2 52 SH   SOLE 1 0 0 52
ADOBE INC COM 00724F101 51,721 118,809 SH   SOLE   118,809 0 0
WHIRLPOOL CORP COM 963320106 467 3,604 SH   SOLE   3,604 0 0
WYNN RESORTS LTD COM 983134107 515 6,913 SH   SOLE   6,913 0 0
AFLAC INC COM 001055102 1 37 SH   SOLE 1 0 0 37
DELL TECHNOLOGIES INC CL C 24703L202 4,909 89,339 SH   SOLE   89,339 0 0
DOMINOS PIZZA INC COM 25754A201 4,832 13,078 SH   SOLE   13,078 0 0
ZOGENIX INC COM NEW 98978L204 25,588 947,329 SH   SOLE   947,329 0 0
AGILENT TECHNOLOGIES INC COM 00846U101 3,752 42,459 SH   SOLE   42,459 0 0
AFLAC INC COM 001055102 1,835 50,924 SH   SOLE   50,924 0 0
KLA CORP COM NEW 482480100 5,888 30,274 SH   SOLE   30,274 0 0
ALPHABET INC CAP STK CL A 02079K305 225,452 158,980 SH   SOLE   158,980 0 0
INTL PAPER CO COM 460146103 1 26 SH   SOLE 1 0 0 26
ISHARES INC MSCI CDA ETF 464286509 2,992 115,591 SH   SOLE   115,591 0 0
ALPHABET INC CAP STK CL A 02079K305 9 6 SH   SOLE 1 0 0 6
LEIDOS HOLDINGS INC COM 525327102 4,321 46,127 SH   SOLE   46,127 0 0
INFOSYS LTD SPONSORED ADR 456788108 3,074 318,207 SH   SOLE   318,207 0 0
BANK NEW YORK MELLON CORP COM 064058100 6,743 174,462 SH   SOLE   174,462 0 0
WEIBO CORP NOTE 1.250%11/1 948596AC5 3,742 4,000 PRN   SOLE   4,000 0 0
DAVITA INC COM 23918K108 3,300 41,698 SH   SOLE   41,698 0 0
PNC FINL SVCS GROUP INC COM 693475105 3,792 36,039 SH   SOLE   36,039 0 0
DIGITAL RLTY TR INC COM 253868103 1,860 13,087 SH   SOLE   13,087 0 0
TRANSUNION COM 89400J107 914 10,498 SH   SOLE   10,498 0 0
TD AMERITRADE HLDG CORP COM 87236Y108 15,443 424,470 SH   SOLE   424,470 0 0
EPAM SYS INC COM 29414B104 7,762 30,800 SH   SOLE   30,800 0 0
IRON MTN INC NEW COM 46284V101 851 32,595 SH   SOLE   32,595 0 0
MARKEL CORP COM 570535104 723 783 SH   SOLE   783 0 0
G1 THERAPEUTICS INC COM 3621LQ109 21,116 870,383 SH   SOLE   870,383 0 0
ISHARES INC MSCI JPN ETF NEW 46434G822 404 620,000 SH Put SOLE   620,000 0 0
ITRON INC COM 465741106 7,205 108,753 SH   SOLE   108,753 0 0
HUBSPOT INC COM 443573100 718 3,200 SH   SOLE   3,200 0 0
TUTOR PERINI CORP COM 901109108 207 17,000 SH   SOLE   17,000 0 0
VISA INC COM CL A 92826C839 73,224 379,049 SH   SOLE   379,049 0 0
IQVIA HLDGS INC COM 46266C105 1,917 13,512 SH   SOLE   13,512 0 0
UDR INC COM 902653104 290 7,763 SH   SOLE   7,763 0 0
DANAHER CORPORATION COM 235851102 11 61 SH   SOLE 1 0 0 61
KIMCO RLTY CORP COM 49446R109 193 15,029 SH   SOLE   15,029 0 0
AVALARA INC COM 05338G106 600 4,510 SH   SOLE   4,510 0 0
SIRIUS XM HOLDINGS INC COM 82968B103 92 15,754 SH   SOLE   15,754 0 0
DEERE & CO COM 244199105 7,333 46,662 SH   SOLE   46,662 0 0
BLACKSTONE GROUP INC COM CL A 09260D107 1,763 31,118 SH   SOLE   31,118 0 0
REPUBLIC SVCS INC COM 760759100 1,924 23,452 SH   SOLE   23,452 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 88,494 1,504,927 SH   SOLE   1,504,927 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 1 14 SH   SOLE 1 0 0 14
NETAPP INC COM 64110D104 869 19,590 SH   SOLE   19,590 0 0
EXELIXIS INC COM 30161Q104 1 48 SH   SOLE 1 0 0 48
TC ENERGY CORP COM 87807B107 936 21,980 SH   SOLE   21,980 0 0
ZOETIS INC CL A 98978V103 4,419 32,245 SH   SOLE   32,245 0 0
FACEBOOK INC CL A 30303M102 3 12 SH   SOLE 1 0 0 12
COMCAST CORP NEW CL A 20030N101 15,193 389,741 SH   SOLE   389,741 0 0
M & T BK CORP COM 55261F104 1,287 12,375 SH   SOLE   12,375 0 0
VERISIGN INC COM 92343E102 2 8 SH   SOLE 1 0 0 8
FORD MTR CO DEL COM 345370860 2 270 SH   SOLE 1 0 0 270
AMERICAN WTR WKS CO INC NEW COM 030420103 3 26 SH   SOLE 1 0 0 26
OMNICOM GROUP INC COM 681919106 2,065 37,824 SH   SOLE   37,824 0 0
AMGEN INC COM 031162100 205,507 871,271 SH   SOLE   871,271 0 0
CONSOLIDATED EDISON INC COM 209115104 4,612 64,110 SH   SOLE   64,110 0 0
ITRON INC COM 465741106 1 21 SH   SOLE 1 0 0 21
TENABLE HLDGS INC COM 88025T102 15,807 530,219 SH   SOLE   530,219 0 0
INGREDION INC COM 457187102 282 3,394 SH   SOLE   3,394 0 0
ARCUS BIOSCIENCES INC COM 03969F109 5,515 222,923 SH   SOLE   222,923 0 0
HILTON WORLDWIDE HLDGS INC COM 43300A203 1,936 26,362 SH   SOLE   26,362 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 4,914 259,439 SH   SOLE   259,439 0 0
XYLEM INC COM 98419M100 18,111 278,791 SH   SOLE   278,791 0 0
METLIFE INC COM 59156R108 2 44 SH   SOLE 1 0 0 44
NVR INC COM 62944T105 890 800 PRN   SOLE   800 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 8,735 591,800 SH   SOLE   591,800 0 0
MACYS INC COM 55616P104 172 25,000 SH   SOLE   25,000 0 0
MGM RESORTS INTERNATIONAL COM 552953101 704 41,917 SH   SOLE   41,917 0 0
IDEX CORP COM 45167R104 1,335 8,447 SH   SOLE   8,447 0 0
ON SEMICONDUCTOR CORP NOTE 1.000%12/0 682189AK1 6,441 5,500 PRN   SOLE   5,500 0 0
ZEBRA TECHNOLOGIES CORPORATI CL A 989207105 10,836 42,335 SH   SOLE   42,335 0 0
AVANTOR INC COM 05352A100 2,907 171,000 SH   SOLE   171,000 0 0
CAMECO CORP COM 13321L108 200 19,546 SH   SOLE   19,546 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 4,609 256,198 SH   SOLE   256,198 0 0
GOODYEAR TIRE & RUBR CO COM 382550101 117 13,031 SH   SOLE   13,031 0 0
ADVANCE AUTO PARTS INC COM 00751Y106 442 3,105 SH   SOLE   3,105 0 0
WESTERN UN CO COM 959802109 531 24,563 SH   SOLE   24,563 0 0
VOYA FINANCIAL INC COM 929089100 248 5,318 SH   SOLE   5,318 0 0
HEALTHPEAK PROPERTIES INC COM 42250P103 1,228 44,568 SH   SOLE   44,568 0 0
ILLUMINA INC COM 452327109 67,974 183,533 SH   SOLE   183,533 0 0
CENTERPOINT ENERGY INC COM 15189T107 2,150 115,139 SH   SOLE   115,139 0 0
UNITED RENTALS INC COM 911363109 5,008 33,598 SH   SOLE   33,598 0 0
SOLAREDGE TECHNOLOGIES INC COM 83417M104 3 21 SH   SOLE 1 0 0 21
ANALOG DEVICES INC COM 032654105 2 14 SH   SOLE 1 0 0 14
DISNEY WALT CO COM DISNEY 254687106 5 43 SH   SOLE 1 0 0 43
MARTIN MARIETTA MATLS INC COM 573284106 1,059 5,127 SH   SOLE   5,127 0 0
HONEYWELL INTL INC COM 438516106 15,282 105,687 SH   SOLE   105,687 0 0
EATON CORP PLC SHS G29183103 2 22 SH   SOLE 1 0 0 22
BANK NOVA SCOTIA B C COM 064149107 2,053 49,773 SH   SOLE   49,773 0 0
VEEVA SYS INC CL A COM 922475108 3,614 15,416 SH   SOLE   15,416 0 0
ILLUMINA INC NOTE 8/1 452327AK5 5,540 5,100 PRN   SOLE   5,100 0 0
MICROSOFT CORP COM 594918104 434,752 2,136,174 SH   SOLE   2,136,174 0 0
VERISK ANALYTICS INC COM 92345Y106 7,537 44,283 SH   SOLE   44,283 0 0
ALLY FINL INC COM 02005N100 742 37,423 SH   SOLE   37,423 0 0
LIBERTY MEDIA CORP DEL COM C SIRIUSXM 531229607 560 16,259 SH   SOLE   16,259 0 0
CUMMINS INC COM 231021106 6,116 35,298 SH   SOLE   35,298 0 0
TRACTOR SUPPLY CO COM 892356106 4,219 32,012 SH   SOLE   32,012 0 0
BOOKING HOLDINGS INC COM 09857L108 9,083 5,704 SH   SOLE   5,704 0 0
ARVINAS INC COM 04335A105 12,218 364,264 SH   SOLE   364,264 0 0
ILLINOIS TOOL WKS INC COM 452308109 4,394 25,130 SH   SOLE   25,130 0 0
DEXCOM INC COM 252131107 6,272 15,471 SH   SOLE   15,471 0 0
AMBEV SA SPONSORED ADR 02319V103 40 15,200 SH   SOLE   15,200 0 0
EPIZYME INC COM 29428V104 1 32 SH   SOLE 1 0 0 32
TJX COS INC NEW COM 872540109 11,666 230,717 SH   SOLE   230,717 0 0
BANK NEW YORK MELLON CORP COM 064058100 1 24 SH   SOLE 1 0 0 24
HOME DEPOT INC COM 437076102 4 16 SH   SOLE 1 0 0 16
EQUINIX INC COM 29444U700 3 4 SH   SOLE 1 0 0 4
G1 THERAPEUTICS INC COM 3621LQ109 1 40 SH   SOLE 1 0 0 40
APELLIS PHARMACEUTICALS INC COM 03753U106 39,533 1,210,398 SH   SOLE   1,210,398 0 0
EQUITY RESIDENTIAL SH BEN INT 29476L107 2,339 39,772 SH   SOLE   39,772 0 0
TRANE TECHNOLOGIES PLC SHS G8994E103 2 24 SH   SOLE 1 0 0 24
PAYPAL HLDGS INC COM 70450Y103 107,922 619,393 SH   SOLE   619,393 0 0
TETRA TECH INC NEW COM 88162G103 896 725 PRN   SOLE   725 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 24,824 167,600 SH   SOLE   167,600 0 0
VALERO ENERGY CORP COM 91913Y100 1,682 28,588 SH   SOLE   28,588 0 0
COHERUS BIOSCIENCES INC COM 19249H103 11,901 666,304 SH   SOLE   666,304 0 0
ELECTRONIC ARTS INC COM 285512109 27,052 204,851 SH   SOLE   204,851 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 158,570 546,185 SH   SOLE   546,185 0 0
PERSONALIS INC COM 71535D106 1 61 SH   SOLE 1 0 0 61
BORGWARNER INC COM 099724106 200 5,676 SH   SOLE   5,676 0 0
VIACOMCBS INC CL B 92556H206 1,232 52,816 SH   SOLE   52,816 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 21,685 38,054 SH   SOLE   38,054 0 0
UNITEDHEALTH GROUP INC COM 91324P102 57,617 195,337 SH   SOLE   195,337 0 0
CHENIERE ENERGY INC COM NEW 16411R208 5,879 121,664 SH   SOLE   121,664 0 0
FACEBOOK INC CL A 30303M102 137,418 605,102 SH   SOLE   605,102 0 0
BURLINGTON STORES INC COM 122017106 641 3,256 SH   SOLE   3,256 0 0
PULTE GROUP INC COM 745867101 6,807 200,027 SH   SOLE   200,027 0 0
BECTON DICKINSON & CO COM 075887109 11,968 50,015 SH   SOLE   50,015 0 0
SQUARE INC CL A 852234103 2,126 20,256 SH   SOLE   20,256 0 0
SILICON LABORATORIES INC COM 826919102 17,195 171,480 SH   SOLE   171,480 0 0
CANADIAN IMP BK COMM COM 136069101 791 11,875 SH   SOLE   11,875 0 0
ALLAKOS INC COM 01671P100 8,039 111,872 SH   SOLE   111,872 0 0
AMERICAN INTL GROUP INC COM NEW 026874784 1,860 59,663 SH   SOLE   59,663 0 0
EXPEDIA GROUP INC COM NEW 30212P303 813 9,894 SH   SOLE   9,894 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 12,551 24,607 SH   SOLE   24,607 0 0
MAGNA INTL INC COM 559222401 394 8,878 SH   SOLE   8,878 0 0
DOMINION ENERGY INC COM 25746U109 4,934 60,777 SH   SOLE   60,777 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 234 3,800 SH   SOLE   3,800 0 0
INCYTE CORP COM 45337C102 33,329 320,552 SH   SOLE   320,552 0 0
FIREEYE INC NOTE 0.875% 6/0 31816QAF8 181 200,000 PRN   SOLE   200,000 0 0
CASELLA WASTE SYS INC CL A 147448104 2,318 44,475 SH   SOLE   44,475 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 1 10 SH   SOLE 1 0 0 10
ILLUMINA INC COM 452327109 2 5 SH   SOLE 1 0 0 5
INTERPUBLIC GROUP COS INC COM 460690100 826 48,141 SH   SOLE   48,141 0 0
T-MOBILE US INC COM 872590104 2,940 28,228 SH   SOLE   28,228 0 0
UNIVERSAL DISPLAY CORP COM 91347P105 21,771 145,504 SH   SOLE   145,504 0 0
BROOKS AUTOMATION INC NEW COM 114340102 16,581 374,787 SH   SOLE   374,787 0 0
CANON INC SPONSORED ADR 138006309 408 20,452 SH   SOLE   20,452 0 0
PAYCHEX INC COM 704326107 1,630 21,514 SH   SOLE   21,514 0 0
MIRATI THERAPEUTICS INC COM 60468T105 0 4 SH   SOLE 1 0 0 4
CARRIER GLOBAL CORPORATION COM 14448C104 1,260 56,714 SH   SOLE   56,714 0 0
EMERSON ELEC CO COM 291011104 28,736 463,242 SH   SOLE   463,242 0 0
CARNIVAL CORP UNIT 99/99/9999 143658300 3,132 190,752 SH   SOLE   190,752 0 0
PALO ALTO NETWORKS INC COM 697435105 29,097 126,685 SH   SOLE   126,685 0 0
ALBEMARLE CORP COM 012653101 405 5,250 SH   SOLE   5,250 0 0
SANOFI SPONSORED ADR 80105N105 2,613 51,183 SH   SOLE   51,183 0 0
CORTEVA INC COM 22052L104 1,810 67,564 SH   SOLE   67,564 0 0
TWITTER INC NOTE 0.250% 6/1 90184LAF9 1,039 1,100 PRN   SOLE   1,100 0 0
BANCO BILBAO VIZCAYA ARGENTA SPONSORED ADR 05946K101 0 113 SH   SOLE 1 0 0 113
ASTRAZENECA PLC SPONSORED ADR 046353108 2,890 54,632 SH   SOLE   54,632 0 0
HONDA MOTOR LTD AMERN SHS 438128308 3 114 SH   SOLE 1 0 0 114
PRUDENTIAL FINL INC COM 744320102 2 34 SH   SOLE 1 0 0 34
TOTAL S.A. SPONSORED ADS 89151E109 6 161 SH   SOLE 1 0 0 161
VISA INC COM CL A 92826C839 3 16 SH   SOLE 1 0 0 16
BOEING CO COM 097023105 1,752 9,558 SH   SOLE   9,558 0 0
CHIPOTLE MEXICAN GRILL INC COM 169656105 1,403 1,333 SH   SOLE   1,333 0 0
CME GROUP INC COM 12572Q105 3,913 24,070 SH   SOLE   24,070 0 0
DARDEN RESTAURANTS INC COM 237194105 4,535 59,854 SH   SOLE   59,854 0 0
XENCOR INC COM 98401F105 1 24 SH   SOLE 1 0 0 24
ARISTA NETWORKS INC COM 040413106 22,484 107,047 SH   SOLE   107,047 0 0
APPLE INC COM 037833100 16 43 SH   SOLE 1 0 0 43
ARGENX SE SPONSORED ADR 04016X101 1 6 SH   SOLE 1 0 0 6
PINDUODUO INC SPONSORED ADS 722304102 39,213 456,800 SH   SOLE   456,800 0 0
EXELIXIS INC COM 30161Q104 9,288 391,238 SH   SOLE   391,238 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 34,503 207,702 SH   SOLE   207,702 0 0
APPLE INC COM 037833100 230,525 631,893 SH   SOLE   631,893 0 0
MARRIOTT INTL INC NEW CL A 571903202 1,814 21,161 SH   SOLE   21,161 0 0
SOUTHWEST AIRLS CO NOTE 1.250% 5/0 844741BG2 21,513 17,900 PRN   SOLE   17,900 0 0
ECOLAB INC COM 278865100 3 14 SH   SOLE 1 0 0 14
PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408 258 31,230 SH   SOLE   31,230 0 0
TREX CO INC COM 89531P105 1 11 SH   SOLE 1 0 0 11
UNION PAC CORP COM 907818108 2 9 SH   SOLE 1 0 0 9
ZSCALER INC COM 98980G102 312 2,850 SH   SOLE   2,850 0 0
TARGET CORP COM 87612E106 1 8 SH   SOLE 1 0 0 8
3M CO COM 88579Y101 10,945 70,159 SH   SOLE   70,159 0 0
ACCURAY INC COM 004397105 142 70,000 SH   SOLE   70,000 0 0
KEYCORP COM 493267108 2,631 215,969 SH   SOLE   215,969 0 0
AKERO THERAPEUTICS INC COM 00973Y108 3,938 158,000 SH   SOLE   158,000 0 0
AUTODESK INC COM 052769106 71,067 297,103 SH   SOLE   297,103 0 0
VENTAS INC COM 92276F100 1,259 34,374 SH   SOLE   34,374 0 0
TRAVELERS COMPANIES INC COM 89417E109 3,352 29,392 SH   SOLE   29,392 0 0
RESMED INC COM 761152107 9,002 46,885 SH   SOLE   46,885 0 0
TESLA INC COM 88160R101 39,132 36,231 SH   SOLE   36,231 0 0
VIEWRAY INC COM 92672L107 2,051 915,497 SH   SOLE   915,497 0 0
ALLSCRIPTS HEALTHCARE SOLUTN COM 01988P108 508 75,000 SH   SOLE   75,000 0 0
KIMBERLY CLARK CORP COM 494368103 37,351 264,231 SH   SOLE   264,231 0 0
DANAHER CORPORATION COM 235851102 105,081 594,223 SH   SOLE   594,223 0 0
ARVINAS INC COM 04335A105 1 21 SH   SOLE 1 0 0 21
ACCELERON PHARMA INC COM 00434H108 36,298 380,985 SH   SOLE   380,985 0 0
ENVIVA PARTNERS LP COM UNIT 29414J107 590 16,367 SH   SOLE   16,367 0 0
FIDELITY NATIONAL FINANCIAL FNF GROUP COM 31620R303 461 15,041 SH   SOLE   15,041 0 0
ISHARES TR MSCI CHINA ETF 46429B671 1,047 16,000 SH   SOLE   16,000 0 0
CVS HEALTH CORP COM 126650100 11,262 173,336 SH   SOLE   173,336 0 0
RALPH LAUREN CORP CL A 751212101 5,198 4,370 PRN   SOLE   4,370 0 0
ACACIA COMMUNICATIONS INC COM 00401C108 4,726 70,341 SH   SOLE   70,341 0 0
WESTPAC BANKING CORP SPONSORED ADR 961214301 1 93 SH   SOLE 1 0 0 93
CENTURYLINK INC COM 156700106 701 69,841 SH   SOLE   69,841 0 0
CISCO SYS INC COM 17275R102 3 59 SH   SOLE 1 0 0 59
CANADIAN NATL RY CO COM 136375102 3,895 44,165 SH   SOLE   44,165 0 0
UNION PAC CORP COM 907818108 31,069 183,755 SH   SOLE   183,755 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 71,149 329,837 SH   SOLE   329,837 0 0
MYOVANT SCIENCES LTD COM G637AM102 1 26 SH   SOLE 1 0 0 26
SNAP ON INC COM 833034101 982 7,088 SH   SOLE   7,088 0 0
MORPHOSYS AG SPONSORED ADS 617760202 2 66 SH   SOLE 1 0 0 66
AMETEK INC COM 031100100 1,879 21,025 SH   SOLE   21,025 0 0
ROKU INC COM CL A 77543R102 593 5,086 SH   SOLE   5,086 0 0
CITIGROUP INC COM NEW 172967424 36,345 711,193 SH   SOLE   711,193 0 0
SBA COMMUNICATIONS CORP NEW CL A 78410G104 7,854 26,360 SH   SOLE   26,360 0 0
BEST BUY INC COM 086516101 22,414 256,828 SH   SOLE   256,828 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 3,556 1,943,000 SH   SOLE   1,943,000 0 0
EPIZYME INC COM 29428V104 4,256 264,982 SH   SOLE   264,982 0 0
STANLEY BLACK & DECKER INC COM 854502101 2,583 18,534 SH   SOLE   18,534 0 0
LOWES COS INC COM 548661107 24,042 177,923 SH   SOLE   177,923 0 0
ABIOMED INC COM 003654100 771 3,191 SH   SOLE   3,191 0 0
ILLUMINA INC NOTE 0.500% 6/1 452327AH2 5,512 3,700 PRN   SOLE   3,700 0 0
WALGREENS BOOTS ALLIANCE INC COM 931427108 1 24 SH   SOLE 1 0 0 24
ZYMEWORKS INC COM 98985W102 1 18 SH   SOLE 1 0 0 18
RALPH LAUREN CORP CL A 751212101 2,686 37,033 SH   SOLE   37,033 0 0
AIR PRODS & CHEMS INC COM 009158106 6 24 SH   SOLE 1 0 0 24
ARCUS BIOSCIENCES INC COM 03969F109 0 19 SH   SOLE 1 0 0 19
TELADOC HEALTH INC COM 87918A105 1,108 1,000 PRN   SOLE   1,000 0 0
WABTEC COM 929740108 1,044 18,134 SH   SOLE   18,134 0 0
WAYFAIR INC CL A 94419L101 783 3,963 SH   SOLE   3,963 0 0
MERCK & CO. INC COM 58933Y105 12 155 SH   SOLE 1 0 0 155
AMARIN CORP PLC SPONS ADR NEW 023111206 4,194 606,000 SH   SOLE   606,000 0 0
MERSANA THERAPEUTICS INC COM 59045L106 13,940 595,708 SH   SOLE   595,708 0 0
INTERNATIONAL BUSINESS MACHS COM 459200101 15,909 131,722 SH   SOLE   131,722 0 0
METTLER TOLEDO INTERNATIONAL COM 592688105 1,631 2,025 SH   SOLE   2,025 0 0
SHOPIFY INC CL A 82509L107 1,341 1,416 SH   SOLE   1,416 0 0
POWER INTEGRATIONS INC COM 739276103 2 15 SH   SOLE 1 0 0 15
FORTRESS BIOTECH INC COM 34960Q109 60 22,500 SH   SOLE   22,500 0 0
WORKIVA INC COM CL A 98139A105 480 8,970 SH   SOLE   8,970 0 0
ANALOG DEVICES INC COM 032654105 43,929 358,178 SH   SOLE   358,178 0 0
DOLLAR GEN CORP NEW COM 256677105 29,043 152,442 SH   SOLE   152,442 0 0
UBER TECHNOLOGIES INC COM 90353T100 1,131 36,381 SH   SOLE   36,381 0 0
VERACYTE INC COM 92337F107 5,413 208,990 SH   SOLE   208,990 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 2 9 SH   SOLE 1 0 0 9
HERSHEY CO COM 427866108 8,921 68,822 SH   SOLE   68,822 0 0
AMAZON COM INC COM 023135106 222,923 80,800 SH   SOLE   80,800 0 0
TOYOTA MOTOR CORP SP ADR REP2COM 892331307 5 40 SH   SOLE 1 0 0 40
VERACYTE INC COM 92337F107 1 25 SH   SOLE 1 0 0 25
TEXAS INSTRS INC COM 882508104 1 10 SH   SOLE 1 0 0 10
VORNADO RLTY TR SH BEN INT 929042109 1 34 SH   SOLE 1 0 0 34
MICROCHIP TECHNOLOGY INC. NOTE 1.625% 2/1 595017AF1 3,771 2,540 PRN   SOLE   2,540 0 0
MARVELL TECHNOLOGY GROUP LTD ORD G5876H105 3,223 91,926 SH   SOLE   91,926 0 0
BEIGENE LTD SPONSORED ADR 07725L102 31,326 166,267 SH   SOLE   166,267 0 0
MASCO CORP COM 574599106 17,779 354,073 SH   SOLE   354,073 0 0
DEVON ENERGY CORP NEW COM 25179M103 1,627 143,497 SH   SOLE   143,497 0 0
WALGREENS BOOTS ALLIANCE INC COM 931427108 2,741 64,664 SH   SOLE   64,664 0 0
HENRY SCHEIN INC COM 806407102 612 10,474 SH   SOLE   10,474 0 0
ABBOTT LABS COM 002824100 43,528 476,059 SH   SOLE   476,059 0 0
CVS HEALTH CORP COM 126650100 3 41 SH   SOLE 1 0 0 41
MEET GROUP INC COM 58513U101 16,706 2,677,137 SH   SOLE   2,677,137 0 0
APTIV PLC SHS G6095L109 2 30 SH   SOLE 1 0 0 30
BALL CORP COM 058498106 2 34 SH   SOLE 1 0 0 34
PRUDENTIAL FINL INC COM 744320102 7,540 123,803 SH   SOLE   123,803 0 0
MCDONALDS CORP COM 580135101 12,554 68,051 SH   SOLE   68,051 0 0