The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
58 COM INC SPON ADR REP A 31680Q104 157,674 2,435,875 SH   SOLE 2,435,875 0 0
ACCELERON PHARMA INC COM 00434H108 2,730 51,489 SH   SOLE 51,489 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 2,752 113,842 SH   SOLE 113,842 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 2,933 61,434 SH   SOLE 61,434 0 0
ALECTOR INC COM 014442107 1,601 92,933 SH   SOLE 92,933 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 365,515 1,723,315 SH   SOLE 1,604,388 0 118,927
ALKERMES PLC SHS G01767105 1,140 55,885 SH   SOLE 55,885 0 0
ALLY FINL INC COM 02005N100 111,141 3,636,827 SH   SOLE 3,177,527 0 459,300
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 1,813 15,741 SH   SOLE 15,741 0 0
ALPHABET INC CAP STK CL A 02079K305 260,187 194,258 SH   SOLE 174,006 0 20,252
ALPHABET INC CAP STK CL C 02079K107 150,706 112,718 SH   SOLE 103,608 0 9,110
AMERICAN EAGLE OUTFITTERS IN COM 02553E106 49,669 3,378,827 SH   SOLE 2,882,653 0 496,174
ANALOG DEVICES INC COM 032654105 1,274 10,720 SH   SOLE 10,720 0 0
APPIAN CORP CL A 03782L101 409 10,693 SH   SOLE 10,693 0 0
APPLE INC COM 037833100 2,070 7,048 SH   SOLE 7,048 0 0
ARCUS BIOSCIENCES INC COM 03969F109 1,048 103,740 SH   SOLE 103,740 0 0
ASLAN PHARMACEUTICALS LTD ADS 04522R101 843 415,450 SH   SOLE 415,450 0 0
AUTOHOME INC SP ADR RP CL A 05278C107 1,411 17,640 SH   SOLE 17,640 0 0
BARRICK GOLD CORPORATION COM 067901108 62,796 3,377,963 SH   SOLE 2,972,333 0 405,630
BIONTECH SE SPONSORED ADS 09075V102 14,189 469,566 SH   SOLE 469,566 0 0
BITAUTO HLDGS LTD SPONSORED ADS 091727107 0 9 SH   SOLE 9 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 1,530 19,094 SH   SOLE 19,094 0 0
BOOKING HLDGS INC COM 09857L108 229,416 111,707 SH   SOLE 99,888 0 11,819
BRF SA SPONSORED ADR 10552T107 12,493 1,436,005 SH   SOLE 1,206,928 0 229,077
CALLAWAY GOLF CO COM 131193104 3,179 149,932 SH   SOLE 149,932 0 0
CARNIVAL CORP UNIT 99/99/9999 143658300 1,487 29,260 SH   SOLE 29,260 0 0
CARVANA CO CL A 146869102 12,503 135,828 SH   SOLE 135,828 0 0
CELLULAR BIOMEDICINE GROUP I COM NEW 15117P102 11,617 715,351 SH   SOLE 715,351 0 0
CENTURYLINK INC COM 156700106 5,711 432,343 SH   SOLE 432,343 0 0
CF INDS HLDGS INC COM 125269100 109,488 2,293,413 SH   SOLE 1,987,179 0 306,234
CISCO SYS INC COM 17275R102 1,712 35,700 SH   SOLE 35,700 0 0
COHERUS BIOSCIENCES INC COM 19249H103 2,886 160,263 SH   SOLE 160,263 0 0
DERMIRA INC COM 24983L104 1,763 116,325 SH   SOLE 116,325 0 0
EBAY INC COM 278642103 1,026 28,417 SH   SOLE 28,417 0 0
EQUIFAX INC COM 294429105 33,894 241,892 SH   SOLE 241,892 0 0
ESPERION THERAPEUTICS INC NE COM 29664W105 2,293 38,454 SH   SOLE 38,454 0 0
FACEBOOK INC CL A 30303M102 410,776 2,001,344 SH   SOLE 1,787,719 0 213,625
FIVE PRIME THERAPEUTICS INC COM 33830X104 1,153 251,216 SH   SOLE 251,216 0 0
FOOT LOCKER INC COM 344849104 8,615 220,944 SH   SOLE 220,944 0 0
FULCRUM THERAPEUTICS INC COM 359616109 2,309 138,767 SH   SOLE 138,767 0 0
GENERAL ELECTRIC CO COM 369604103 123,291 11,047,576 SH   SOLE 10,151,137 0 896,439
GILEAD SCIENCES INC COM 375558103 179,129 2,756,683 SH   SOLE 2,427,357 0 329,326
GOLDEN OCEAN GROUP LTD SHS NEW G39637205 170,683 3,350,000 SH   SOLE 3,350,000 0 0
HANESBRANDS INC COM 410345102 11,797 794,404 SH   SOLE 794,404 0 0
IHS MARKIT LTD SHS G47567105 23,678 314,239 SH   SOLE 314,239 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 1,092 1,137,647 SH   SOLE 1,137,647 0 0
INTEL CORP COM 458140100 277,410 4,635,094 SH   SOLE 4,112,908 0 522,186
INTELLIA THERAPEUTICS INC COM 45826J105 971 66,170 SH   SOLE 66,170 0 0
JD COM INC SPON ADR CL A 47215P106 1,261 35,800 SH   SOLE 35,800 0 0
JOHNSON & JOHNSON COM 478160104 3,501 24,000 SH   SOLE 24,000 0 0
KONTOOR BRANDS INC COM 50050N103 6,556 156,139 SH   SOLE 156,139 0 0
LAM RESEARCH CORP COM 512807108 2,904 9,931 SH   SOLE 9,931 0 0
LIBERTY GLOBAL PLC SHS CL A G5480U104 337 14,800 SH   SOLE 14,800 0 0
LIVANOVA PLC SHS G5509L101 1,712 22,698 SH   SOLE 22,698 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 3,154 208,038 SH   SOLE 208,038 0 0
MELCO RESORTS AND ENTMT LTD ADR 585464100 78,641 3,253,643 SH   SOLE 3,253,643 0 0
MERUS N V COM N5749R100 2,395 170,112 SH   SOLE 170,112 0 0
MICROCHIP TECHNOLOGY INC COM 595017104 215,726 2,060,023 SH   SOLE 1,829,842 0 230,181
MICRON TECHNOLOGY INC COM 595112103 258,094 4,799,063 SH   SOLE 4,175,000 0 624,063
MICROSOFT CORP COM 594918104 3,942 24,998 SH   SOLE 24,998 0 0
MODERNA INC COM 60770K107 28,410 1,452,472 SH   SOLE 1,280,614 0 171,858
MOMO INC ADR 60879B107 148,374 4,429,069 SH   SOLE 4,429,069 0 0
MYOVANT SCIENCES LTD COM G637AM102 4,119 265,381 SH   SOLE 265,381 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 3,064 110,125 SH   SOLE 110,125 0 0
NIELSEN HLDGS PLC SHS EUR G6518L108 4,882 240,481 SH   SOLE 240,481 0 0
NOAH HLDGS LTD SPON ADS CL A 65487X102 40,518 1,145,551 SH   SOLE 1,145,551 0 0
NORBORD INC COM NEW 65548P403 357 13,344 SH   SOLE 13,344 0 0
ORACLE CORP COM 68389X105 1,559 29,418 SH   SOLE 29,418 0 0
OVID THERAPEUTICS INC COM 690469101 1,271 306,146 SH   SOLE 306,146 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,272 247,475 SH   SOLE 247,475 0 0
PAYPAL HLDGS INC COM 70450Y103 1,778 16,437 SH   SOLE 16,437 0 0
PEABODY ENERGY CORP NEW COM 704551100 35,281 3,868,571 SH   SOLE 3,505,134 0 363,437
PERKINELMER INC COM 714046109 2,655 27,347 SH   SOLE 27,347 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 1,100 303,866 SH   SOLE 303,866 0 0
PROTHENA CORP PLC SHS G72800108 2,231 140,943 SH   SOLE 140,943 0 0
QIAGEN NV SHS NEW N72482123 19,066 625,943 SH   SOLE 625,943 0 0
QIWI PLC SPON ADR REP B 74735M108 7,744 400,000 SH   SOLE 400,000 0 0
QUANTERIX CORP COM 74766Q101 4,196 177,554 SH   SOLE 177,554 0 0
ROKU INC COM CL A 77543R102 991 7,398 SH   SOLE 7,398 0 0
SANGAMO THERAPEUTICS INC COM 800677106 1,643 196,265 SH   SOLE 196,265 0 0
SCHLUMBERGER LTD COM 806857108 43,359 1,078,572 SH   SOLE 885,926 0 192,646
SEATTLE GENETICS INC COM 812578102 927 8,110 SH   SOLE 8,110 0 0
SINA CORP ORD G81477104 660 16,524 SH   SOLE 16,524 0 0
SKYWORKS SOLUTIONS INC COM 83088M102 302,143 2,499,532 SH   SOLE 2,223,673 0 275,859
SPIRIT AIRLS INC COM 848577102 33,407 828,743 SH   SOLE 828,743 0 0
STARS GROUP INC COM 85570W100 15,144 580,440 SH   SOLE 580,440 0 0
TECHNIPFMC PLC COM G87110105 185,797 8,665,883 SH   SOLE 7,512,583 0 1,153,300
TRANSOCEAN LTD REG SHS H8817H100 125,241 18,203,700 SH   SOLE 16,220,961 0 1,982,739
TRIP COM GROUP LTD ADS 89677Q107 93,706 2,793,848 SH   SOLE 2,793,848 0 0
TWILIO INC CL A 90138F102 416 4,229 SH   SOLE 4,229 0 0
WABTEC CORP COM 929740108 4,268 54,855 SH   SOLE 50,041 0 4,814
WARRIOR MET COAL INC COM 93627C101 17,170 812,600 SH   SOLE 679,300 0 133,300
WAVE LIFE SCIENCES LTD SHS Y95308105 553 68,957 SH   SOLE 68,957 0 0
WEIBO CORP SPONSORED ADR 948596101 65,783 1,419,269 SH   SOLE 1,165,620 0 253,649
XILINX INC COM 983919101 900 9,209 SH   SOLE 9,209 0 0
YUM CHINA HLDGS INC COM 98850P109 85,226 1,775,164 SH   SOLE 1,775,164 0 0
ZAI LAB LTD ADR 98887Q104 4,539 109,129 SH   SOLE 109,129 0 0
ZTO EXPRESS CAYMAN INC SPONSORED ADS A 98980A105 346,868 14,855,155 SH   SOLE 13,217,570 0 1,637,585