The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109 75,720 1,000,000 SH   OTR   1,000,000 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 12,597 350,000 SH   OTR   350,000 0 0
ACCELERON PHARMA INC COM 00434H108 94,824 2,400,000 SH   OTR   2,400,000 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 78,552 4,165,000 SH   OTR   4,165,000 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 363,678 2,174,715 SH   OTR   2,174,715 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 120,630 1,500,000 SH   OTR   1,500,000 0 0
ALPHABET INC CAP STK CL C 02079K107 304,795 250,037 SH   OTR   250,037 0 0
ALTABA INC COM 021346101 666,011 34,189,499 SH   OTR   34,189,499 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 30,329 2,000,600 SH   OTR   2,000,600 0 0
ANTHEM INC COM 036752103 255,198 1,062,883 SH   OTR   1,062,883 0 0
APTINYX INC COM 03836N103 2,353 674,141 SH   OTR   674,141 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 18,317 650,000 SH   OTR   650,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 149,296 1,550,000 SH   OTR   1,550,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 105,889 2,375,785 SH   OTR   2,375,785 0 0
AVROBIO INC COM 05455M100 21,886 1,550,000 SH   OTR   1,550,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104 8,096 400,000 SH   OTR   400,000 0 0
BOOKING HLDGS INC COM 09857L108 61,114 31,139 SH   OTR   31,139 0 0
BUCKEYE PARTNERS L P UNIT LTD PARTN 118230101 160,251 3,900,000 SH   OTR   3,900,000 0 0
CARA THERAPEUTICS INC COM 140755109 39,302 2,150,000 SH   OTR   2,150,000 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 290,672 705,309 SH   OTR   705,309 0 0
CHEMOCENTRYX INC COM 16383L106 13,651 2,013,396 SH   OTR   2,013,396 0 0
CIGNA CORP NEW COM 125523100 161,321 1,062,790 SH   OTR   1,062,790 0 0
CITRIX SYS INC COM 177376100 183,419 1,900,323 SH   OTR   1,900,323 0 0
CLOVIS ONCOLOGY INC NOTE 1.250% 5/0 189464AC4 8,261 18,801,000 PRN   OTR   18,801,000 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 22,969 560,367 SH   OTR   560,367 0 0
CVS HEALTH CORP COM 126650100 56,763 900,000 SH   OTR   900,000 0 0
CYCLERION THERAPEUTICS INC COM 23255M105 4,565 376,628 SH   OTR   376,628 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 25,455 750,000 SH   OTR   750,000 0 0
DERMTECH INC COM 24984K105 3,446 615,385 SH   OTR   615,385 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 11,531 1,125,000 SH   OTR   1,125,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 76,555 1,274,212 SH   OTR   1,274,212 0 0
EQUIFAX INC COM 294429105 89,333 635,056 SH   OTR   635,056 0 0
EQUINIX INC COM 29444U700 214,379 371,670 SH   OTR   371,670 0 0
EXAGEN INC COM 30068X103 5,628 363,336 SH   OTR   363,336 0 0
EXELIXIS INC COM 30161Q104 30,949 1,750,000 SH   OTR   1,750,000 0 0
FACEBOOK INC CL A 30303M102 242,815 1,363,514 SH   OTR   1,363,514 0 0
FATE THERAPEUTICS INC COM 31189P102 34,943 2,250,000 SH   OTR   2,250,000 0 0
FIBROGEN INC COM 31572Q808 36,980 1,000,000 SH   OTR   1,000,000 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 405,663 3,055,609 SH   OTR   3,055,609 0 0
GENERAL DYNAMICS CORP COM 369550108 181,219 991,732 SH   OTR   991,732 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 78,218 1,612,069 SH   OTR   1,612,069 0 0
GOSSAMER BIO INC COM 38341P102 1,691 100,712 SH   OTR   100,712 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 62,389 3,113,222 SH   OTR 1 3,113,222 0 0
IAC INTERACTIVECORP COM 44919P508 317,691 1,457,500 SH   OTR   1,457,500 0 0
IHS MARKIT LTD SHS G47567105 239,122 3,575,384 SH   OTR   3,575,384 0 0
II VI INC COM 902104108 1,679 47,687 SH   OTR   47,687 0 0
INVITAE CORP COM 46185L103 25,051 1,300,000 SH   OTR   1,300,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 109,655 6,025,000 SH   OTR   6,025,000 0 0
IQVIA HLDGS INC COM 46266C105 394,390 2,640,179 SH   OTR   2,640,179 0 0
MICROSOFT CORP COM 594918104 196,626 1,414,272 SH   OTR   1,414,272 0 0
MIRATI THERAPEUTICS INC COM 60468T105 23,373 300,000 SH   OTR   300,000 0 0
MYOKARDIA INC COM 62857M105 105,885 2,030,397 SH   OTR   2,030,397 0 0
NXP SEMICONDUCTORS N V COM N6596X109 35,464 325,000 SH   OTR   325,000 0 0
PALO ALTO NETWORKS INC COM 697435105 124,336 610,000 SH   OTR   610,000 0 0
PFENEX INC COM 717071104 5,064 600,000 SH   OTR   600,000 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 3,369 807,928 SH   OTR   807,928 0 0
PLAYA HOTELS & RESORTS NV SHS N70544106 239,652 30,606,930 SH   OTR   30,606,930 0 0
PROGENICS PHARMACEUTICALS IN COM 743187106 37,154 7,350,000 SH   OTR   7,350,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 18,015 1,500,000 SH   OTR   1,500,000 0 0
PTC THERAPEUTICS INC COM 69366J200 24,587 726,986 SH   OTR   726,986 0 0
PTC THERAPEUTICS INC NOTE 3.000% 8/1 69366JAB7 25,210 24,176,000 PRN   OTR   24,176,000 0 0
QUOTIENT LTD SHS G73268107 13,209 1,700,000 SH   OTR   1,700,000 0 0
RADIUS HEALTH INC COM NEW 750469207 52,903 2,054,486 SH   OTR   2,054,486 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 1,140 1,250,000 PRN   OTR   1,250,000 0 0
READY CAP CORP COM 75574U101 35,106 2,205,132 SH   OTR   2,205,132 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 14,618 182,060 SH   OTR   182,060 0 0
S&P GLOBAL INC COM 78409V104 203,900 832,314 SH   OTR   832,314 0 0
SAGE THERAPEUTICS INC COM 78667J108 52,300 372,800 SH   OTR   372,800 0 0
SANOFI RIGHT 12/31/2020 80105N113 3,892 6,827,805 SH   OTR   6,827,805 0 0
SAVARA INC COM 805111101 9,304 3,510,787 SH   OTR   3,510,787 0 0
SEA LTD SPONSORED ADS 81141R100 104,456 3,375,000 SH   OTR   3,375,000 0 0
SHERWIN WILLIAMS CO COM 824348106 247,415 449,952 SH   OTR   449,952 0 0
SOLARCITY CORP NOTE 1.625%11/0 83416TAC4 17,175 17,370,000 PRN   OTR   17,370,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 981,122 3,306,000 SH Put OTR   3,306,000 0 0
STEMLINE THERAPEUTICS INC COM 85858C107 23,943 2,300,000 SH   OTR   2,300,000 0 0
SYMANTEC CORP COM 871503108 24,339 1,030,000 SH   OTR   1,030,000 0 0
TRANSUNION COM 89400J107 101,804 1,255,138 SH   OTR   1,255,138 0 0
TRICIDA INC COM 89610F101 15,435 500,000 SH   OTR   500,000 0 0
TRINITY MERGER CORP COM CL A 89653L106 77,278 75,000,000 SH   OTR   75,000,000 0 0
UBER TECHNOLOGIES INC COM 90353T100 33,593 1,102,500 SH Put OTR   1,102,500 0 0
UNIQURE NV SHS N90064101 3,972 100,922 SH   OTR   10,922 0 0
VERACYTE INC COM 92337F107 24,000 1,000,000 SH   OTR   1,000,000 0 0
VISA INC COM CL A 92826C839 222,797 1,295,257 SH   OTR   1,295,257 0 0
WABTEC CORP COM 929740108 450,633 6,270,986 SH   OTR   6,270,986 0 0
ZAFGEN INC COM 98885E103 1,336 1,808,360 SH   OTR   1,808,360 0 0
ZAYO GROUP HLDGS INC COM 98919V105 167,610 4,944,247 SH   OTR   4,944,247 0 0
ZEALAND PHARMA A S SPONSORED ADR 98920Y304 25,614 1,010,000 SH   OTR   1,010,000 0 0
ZOGENIX INC COM NEW 98978L204 70,070 1,750,000 SH   OTR   1,750,000 0 0
ZYMEWORKS INC COM 98985W102 42,941 1,731,500 SH   OTR   1,731,500 0 0