The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2U | COM | 90214J101 | 12,433 | 763,717 | SH | DFND | 1 | 763,717 | 0 | 0 | |
| 2U | COM | 90214J101 | 4,335 | 266,293 | SH | SOLE | 0 | 266,293 | 0 | 0 | |
| 2U | COM | 90214J101 | 165 | 10,113 | SH | DFND | 3 | 10,113 | 0 | 0 | |
| 2U | COM | 90214J101 | 12,879 | 791,120 | SH | DFND | 2 | 22,609 | 0 | 768,511 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 28,865 | 585,388 | SH | DFND | 1 | 585,388 | 0 | 0 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 69,773 | 1,414,977 | SH | SOLE | 0 | 1,374,605 | 0 | 40,372 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 23,802 | 482,697 | SH | DFND | 3 | 338,911 | 0 | 143,786 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 106,291 | 2,155,576 | SH | DFND | 2 | 1,627,684 | 0 | 527,892 | |
| AJ Gallagher & Co | COM | 363576109 | 288,923 | 3,225,669 | SH | DFND | 2 | 2,443,672 | 0 | 781,997 | |
| AJ Gallagher & Co | COM | 363576109 | 85,702 | 956,813 | SH | DFND | 1 | 956,813 | 0 | 0 | |
| AJ Gallagher & Co | COM | 363576109 | 60,780 | 678,579 | SH | DFND | 3 | 473,499 | 0 | 205,080 | |
| AJ Gallagher & Co | COM | 363576109 | 191,737 | 2,140,644 | SH | SOLE | 0 | 2,081,523 | 0 | 59,121 | |
| Abiomed | COM | 003654100 | 215,794 | 1,213,078 | SH | DFND | 2 | 588,842 | 0 | 624,236 | |
| Abiomed | COM | 003654100 | 126,084 | 708,774 | SH | DFND | 1 | 708,774 | 0 | 0 | |
| Abiomed | COM | 003654100 | 29,733 | 167,145 | SH | DFND | 3 | 118,690 | 0 | 48,455 | |
| Abiomed | COM | 003654100 | 107,379 | 603,624 | SH | SOLE | 0 | 591,740 | 0 | 11,884 | |
| Acacia Research Corp | ACACIA TCH COM | 003881307 | 385 | 143,640 | SH | DFND | 1 | 143,640 | 0 | 0 | |
| Acacia Research Corp | ACACIA TCH COM | 003881307 | 595 | 222,180 | SH | SOLE | 0 | 222,180 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 35,850 | 677,444 | SH | DFND | 1 | 677,444 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 53,872 | 1,017,994 | SH | DFND | 2 | 345,496 | 0 | 672,498 | |
| Activision Blizzard Inc | COM | 00507V109 | 482 | 9,114 | SH | DFND | 3 | 9,114 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 10,839 | 204,811 | SH | SOLE | 0 | 204,811 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 3,074 | 2,035,855 | SH | DFND | 1 | 2,035,855 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 1,058 | 700,697 | SH | SOLE | 0 | 700,697 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 405 | 268,099 | SH | DFND | 3 | 268,099 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 1,752 | 1,160,156 | SH | DFND | 2 | 402,147 | 0 | 758,009 | |
| Aduro Biotechnology | COM | 00739L101 | 2,100 | 1,980,937 | SH | DFND | 1 | 1,980,937 | 0 | 0 | |
| Aduro Biotechnology | COM | 00739L101 | 1,321 | 1,246,208 | SH | DFND | 2 | 421,520 | 0 | 824,688 | |
| Aduro Biotechnology | COM | 00739L101 | 333 | 314,018 | SH | DFND | 3 | 314,018 | 0 | 0 | |
| Aduro Biotechnology | COM | 00739L101 | 620 | 585,293 | SH | SOLE | 0 | 585,293 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 15,517 | 289,717 | SH | DFND | 1 | 289,717 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 12,184 | 227,480 | SH | DFND | 2 | 78,747 | 0 | 148,733 | |
| Aerovironment | COM | 008073108 | 11,814 | 220,567 | SH | SOLE | 0 | 220,567 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 3,100 | 57,882 | SH | DFND | 3 | 57,882 | 0 | 0 | |
| Agios Pharmaceuticals | COM | 00847X104 | 261 | 8,045 | SH | DFND | 3 | 8,045 | 0 | 0 | |
| Agios Pharmaceuticals | COM | 00847X104 | 14,794 | 456,597 | SH | DFND | 1 | 456,597 | 0 | 0 | |
| Agios Pharmaceuticals | COM | 00847X104 | 15,142 | 467,336 | SH | DFND | 2 | 13,714 | 0 | 453,622 | |
| Agios Pharmaceuticals | COM | 00847X104 | 4,916 | 151,716 | SH | SOLE | 0 | 151,716 | 0 | 0 | |
| Albemarle Corp | COM | 012653101 | 42,552 | 612,090 | SH | DFND | 1 | 612,090 | 0 | 0 | |
| Albemarle Corp | COM | 012653101 | 94,235 | 1,355,505 | SH | SOLE | 0 | 1,321,382 | 0 | 34,123 | |
| Albemarle Corp | COM | 012653101 | 27,838 | 400,431 | SH | DFND | 3 | 281,744 | 0 | 118,687 | |
| Albemarle Corp | COM | 012653101 | 133,115 | 1,914,766 | SH | DFND | 2 | 1,454,270 | 0 | 460,496 | |
| Alector Inc | COM | 014442107 | 30 | 2,072 | SH | DFND | 3 | 2,072 | 0 | 0 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 597,368 | 3,572,135 | SH | DFND | 1 | 3,572,135 | 0 | 0 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 441,959 | 2,642,824 | SH | DFND | 3 | 927,498 | 0 | 1,715,326 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 5,664,080 | 33,869,997 | SH | DFND | 2 | 13,049,619 | 0 | 20,820,378 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 1,596,451 | 9,546,442 | SH | SOLE | 0 | 8,053,142 | 0 | 1,493,300 | |
| Align Technology Inc | COM | 016255101 | 9,236 | 51,052 | SH | DFND | 2 | 51,052 | 0 | 0 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 144,193 | 1,793,003 | SH | DFND | 1 | 1,793,003 | 0 | 0 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 283,301 | 3,522,773 | SH | DFND | 2 | 2,057,152 | 0 | 1,465,621 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 50,213 | 624,389 | SH | DFND | 3 | 479,978 | 0 | 144,411 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 184,629 | 2,295,809 | SH | SOLE | 0 | 2,254,983 | 0 | 40,826 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 5,935 | 4,860 | SH | DFND | 3 | 3,225 | 0 | 1,635 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 37,020 | 30,316 | SH | DFND | 2 | 27,508 | 0 | 2,808 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 23,134 | 18,945 | SH | DFND | 1 | 18,945 | 0 | 0 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 89,218 | 73,061 | SH | SOLE | 0 | 73,061 | 0 | 0 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 1,480,260 | 1,214,323 | SH | DFND | 2 | 558,799 | 0 | 655,524 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 427,736 | 350,891 | SH | DFND | 1 | 350,891 | 0 | 0 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 155,870 | 127,867 | SH | DFND | 3 | 83,813 | 0 | 44,054 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 744,212 | 610,510 | SH | SOLE | 0 | 488,991 | 0 | 121,519 | |
| Amazon.Com | COM | 023135106 | 4,404,531 | 2,537,304 | SH | DFND | 2 | 787,471 | 0 | 1,749,833 | |
| Amazon.Com | COM | 023135106 | 853,504 | 491,675 | SH | DFND | 1 | 491,675 | 0 | 0 | |
| Amazon.Com | COM | 023135106 | 281,999 | 162,450 | SH | DFND | 3 | 104,385 | 0 | 58,065 | |
| Amazon.Com | COM | 023135106 | 2,162,081 | 1,245,503 | SH | SOLE | 0 | 1,064,458 | 0 | 181,045 | |
| Ambarella | SHS | G037AX101 | 9,268 | 147,500 | SH | DFND | 1 | 147,500 | 0 | 0 | |
| Ambarella | SHS | G037AX101 | 6,133 | 97,605 | SH | SOLE | 0 | 97,605 | 0 | 0 | |
| Ambarella | SHS | G037AX101 | 1,995 | 31,752 | SH | DFND | 3 | 31,752 | 0 | 0 | |
| Ambarella | SHS | G037AX101 | 7,753 | 123,389 | SH | DFND | 2 | 42,772 | 0 | 80,617 | |
| Ambev ADR | SPONSORED ADR | 02319V103 | 12 | 2,511 | SH | DFND | 3 | 2,511 | 0 | 0 | |
| American Express | COM | 025816109 | 2,319 | 19,607 | SH | SOLE | 0 | 19,607 | 0 | 0 | |
| American Express | COM | 025816109 | 2,268 | 19,175 | SH | DFND | 1 | 19,175 | 0 | 0 | |
| American Express | COM | 025816109 | 20,009 | 169,169 | SH | DFND | 2 | 169,169 | 0 | 0 | |
| American Express | COM | 025816109 | 1,510 | 12,770 | SH | DFND | 3 | 7,877 | 0 | 4,893 | |
| Analog Devices | COM | 032654105 | 19 | 174 | SH | DFND | 3 | 174 | 0 | 0 | |
| Analog Devices | COM | 032654105 | 989 | 8,850 | SH | DFND | 2 | 0 | 0 | 8,850 | |
| Analog Devices | COM | 032654105 | 15,076 | 134,931 | SH | DFND | 1 | 134,931 | 0 | 0 | |
| Analog Devices | COM | 032654105 | 18,312 | 163,895 | SH | SOLE | 0 | 163,895 | 0 | 0 | |
| Anaplan Inc Common | COM | 03272L108 | 87,967 | 1,871,644 | SH | SOLE | 0 | 1,871,644 | 0 | 0 | |
| Annaly Capital Man. | COM | 035710409 | 156 | 17,762 | SH | DFND | 1 | 17,762 | 0 | 0 | |
| Anthem Inc | COM | 036752103 | 104,046 | 433,345 | SH | DFND | 3 | 303,413 | 0 | 129,932 | |
| Anthem Inc | COM | 036752103 | 482,036 | 2,007,645 | SH | DFND | 2 | 1,515,068 | 0 | 492,577 | |
| Anthem Inc | COM | 036752103 | 126,036 | 524,933 | SH | DFND | 1 | 524,933 | 0 | 0 | |
| Anthem Inc | COM | 036752103 | 316,452 | 1,318,001 | SH | SOLE | 0 | 1,280,956 | 0 | 37,045 | |
| Apache Corp | COM | 037411105 | 62,472 | 2,440,298 | SH | DFND | 1 | 2,440,298 | 0 | 0 | |
| Apache Corp | COM | 037411105 | 214,816 | 8,391,247 | SH | DFND | 2 | 6,331,142 | 0 | 2,060,105 | |
| Apache Corp | COM | 037411105 | 40,779 | 1,592,912 | SH | DFND | 3 | 1,042,325 | 0 | 550,587 | |
| Apache Corp | COM | 037411105 | 144,395 | 5,640,423 | SH | SOLE | 0 | 5,485,397 | 0 | 155,026 | |
| Apollo Commercial Real Estate Finance REIT | COM | 03762U105 | 232 | 12,100 | SH | DFND | 1 | 12,100 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 58,190 | 1,225,053 | SH | DFND | 1 | 1,225,053 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 53,598 | 1,128,378 | SH | DFND | 2 | 126,353 | 0 | 1,002,025 | |
| Appian Corp | CL A | 03782L101 | 4,093 | 86,160 | SH | DFND | 3 | 86,160 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 33,585 | 707,048 | SH | SOLE | 0 | 707,048 | 0 | 0 | |
| Apple | COM | 037833100 | 9,152 | 40,863 | SH | DFND | 1 | 40,863 | 0 | 0 | |
| Apple | COM | 037833100 | 692 | 3,088 | SH | DFND | 2 | 0 | 0 | 3,088 | |
| Apple | COM | 037833100 | 11,022 | 49,210 | SH | SOLE | 0 | 49,210 | 0 | 0 | |
| Apple | COM | 037833100 | 11 | 51 | SH | DFND | 3 | 51 | 0 | 0 | |
| Aslan Pharmaceuticals ADR | ADS | 04522R101 | 272 | 157,248 | SH | SOLE | 0 | 157,248 | 0 | 0 | |
| Aslan Pharmaceuticals ADR | ADS | 04522R101 | 452 | 261,423 | SH | DFND | 1 | 261,423 | 0 | 0 | |
| Atlassian Corp Plc | CL A | G06242104 | 95,746 | 763,278 | SH | DFND | 1 | 763,278 | 0 | 0 | |
| Atlassian Corp Plc | CL A | G06242104 | 583,976 | 4,655,417 | SH | DFND | 2 | 1,700,562 | 0 | 2,954,855 | |
| Atlassian Corp Plc | CL A | G06242104 | 37,946 | 302,507 | SH | DFND | 3 | 167,836 | 0 | 134,671 | |
| Atlassian Corp Plc | CL A | G06242104 | 197,595 | 1,575,214 | SH | SOLE | 0 | 784,024 | 0 | 791,190 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 126,356 | 1,519,977 | SH | DFND | 2 | 1,156,208 | 0 | 363,769 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 33,608 | 404,288 | SH | DFND | 1 | 404,288 | 0 | 0 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 27,699 | 333,202 | SH | DFND | 3 | 235,012 | 0 | 98,190 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 86,392 | 1,039,239 | SH | SOLE | 0 | 1,011,473 | 0 | 27,766 | |
| Axogen Inc | COM | 05463X106 | 4,482 | 359,100 | SH | DFND | 1 | 359,100 | 0 | 0 | |
| Axogen Inc | COM | 05463X106 | 4,623 | 370,400 | SH | DFND | 2 | 127,500 | 0 | 242,900 | |
| Axogen Inc | COM | 05463X106 | 1,127 | 90,300 | SH | DFND | 3 | 90,300 | 0 | 0 | |
| Axogen Inc | COM | 05463X106 | 2,117 | 169,600 | SH | SOLE | 0 | 169,600 | 0 | 0 | |
| Axon Enterprise Inc | COM | 05464C101 | 36,414 | 641,315 | SH | DFND | 1 | 641,315 | 0 | 0 | |
| Axon Enterprise Inc | COM | 05464C101 | 24,671 | 434,510 | SH | DFND | 3 | 321,178 | 0 | 113,332 | |
| Axon Enterprise Inc | COM | 05464C101 | 110,581 | 1,947,537 | SH | DFND | 2 | 1,391,357 | 0 | 556,180 | |
| Axon Enterprise Inc | COM | 05464C101 | 71,468 | 1,258,674 | SH | SOLE | 0 | 1,226,145 | 0 | 32,529 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 18,742 | 182,390 | SH | DFND | 3 | 11,347 | 0 | 171,043 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 841,491 | 8,188,894 | SH | DFND | 2 | 2,527,056 | 0 | 5,661,838 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 7,381 | 71,830 | SH | DFND | 1 | 71,830 | 0 | 0 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 116,498 | 1,133,692 | SH | SOLE | 0 | 1,133,692 | 0 | 0 | |
| BanColombia Pref ADR | SPON ADR PREF | 05968L102 | 12,716 | 257,155 | SH | DFND | 2 | 0 | 0 | 257,155 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 27,997 | 3,439,375 | SH | DFND | 1 | 3,439,375 | 0 | 0 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 180,637 | 22,191,223 | SH | DFND | 2 | 9,660,532 | 0 | 12,530,691 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 22,341 | 2,744,583 | SH | DFND | 3 | 2,641,523 | 0 | 103,060 | |
| Banco Macro ADR | SPON ADR B | 05961W105 | 2,863 | 110,039 | SH | DFND | 1 | 110,039 | 0 | 0 | |
| Banco Macro ADR | SPON ADR B | 05961W105 | 16,798 | 645,576 | SH | DFND | 2 | 294,238 | 0 | 351,338 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 22,704 | 531,708 | SH | DFND | 1 | 531,708 | 0 | 0 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 17,585 | 411,826 | SH | DFND | 2 | 142,280 | 0 | 269,546 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 4,456 | 104,362 | SH | DFND | 3 | 104,362 | 0 | 0 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 12,558 | 294,100 | SH | SOLE | 0 | 294,100 | 0 | 0 | |
| Beigene Ltd | SPONSORED ADR | 07725L102 | 9,106 | 74,362 | SH | DFND | 1 | 74,362 | 0 | 0 | |
| Beigene Ltd | SPONSORED ADR | 07725L102 | 41,360 | 337,747 | SH | DFND | 2 | 150,778 | 0 | 186,969 | |
| Beigene Ltd | SPONSORED ADR | 07725L102 | 9,403 | 76,785 | SH | DFND | 3 | 0 | 0 | 76,785 | |
| Benefitfocus Inc | COM | 08180D106 | 1,746 | 73,334 | SH | DFND | 3 | 73,334 | 0 | 0 | |
| Benefitfocus Inc | COM | 08180D106 | 6,353 | 266,817 | SH | DFND | 2 | 74,720 | 0 | 192,097 | |
| Benefitfocus Inc | COM | 08180D106 | 7,297 | 306,448 | SH | DFND | 1 | 306,448 | 0 | 0 | |
| Benefitfocus Inc | COM | 08180D106 | 5,390 | 226,368 | SH | SOLE | 0 | 226,368 | 0 | 0 | |
| BitAuto Holdings Ltd - ADR | SPONSORED ADS | 091727107 | 816 | 54,492 | SH | SOLE | 0 | 54,492 | 0 | 0 | |
| BlackRock Floating Rate Income | COM | 091941104 | 9,666 | 787,770 | SH | DFND | 1 | 787,770 | 0 | 0 | |
| Blackline | COM | 09239B109 | 12,560 | 262,705 | SH | DFND | 1 | 262,705 | 0 | 0 | |
| Blackline | COM | 09239B109 | 10,046 | 210,123 | SH | DFND | 2 | 72,598 | 0 | 137,525 | |
| Blackline | COM | 09239B109 | 2,554 | 53,416 | SH | DFND | 3 | 53,416 | 0 | 0 | |
| Blackline | COM | 09239B109 | 6,654 | 139,175 | SH | SOLE | 0 | 139,175 | 0 | 0 | |
| Blue Apron Holdings Inc | CL A | 09523Q101 | 1,252 | 148,506 | SH | DFND | 1 | 148,506 | 0 | 0 | |
| Blue Capital Reinsurance Holdings Fund (USD) | COM | G1190F107 | 4,558 | 618,438 | SH | DFND | 1 | 618,438 | 0 | 0 | |
| Bluebird Bio Inc | COM | 09609G100 | 25,263 | 275,136 | SH | DFND | 1 | 275,136 | 0 | 0 | |
| Bluebird Bio Inc | COM | 09609G100 | 150,666 | 1,640,888 | SH | DFND | 2 | 593,996 | 0 | 1,046,892 | |
| Bluebird Bio Inc | COM | 09609G100 | 131,196 | 1,428,835 | SH | SOLE | 0 | 1,147,559 | 0 | 281,276 | |
| Bluebird Bio Inc | COM | 09609G100 | 10,188 | 110,957 | SH | DFND | 3 | 63,259 | 0 | 47,698 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 3,617 | 98,030 | SH | DFND | 1 | 98,030 | 0 | 0 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 212 | 5,757 | SH | DFND | 2 | 0 | 0 | 5,757 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 6 | 158 | SH | DFND | 3 | 158 | 0 | 0 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 4,281 | 116,021 | SH | SOLE | 0 | 116,021 | 0 | 0 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 58,008 | 466,186 | SH | DFND | 1 | 466,186 | 0 | 0 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 46,984 | 377,593 | SH | DFND | 3 | 265,213 | 0 | 112,380 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 216,752 | 1,741,957 | SH | DFND | 2 | 1,315,641 | 0 | 426,316 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 141,613 | 1,138,094 | SH | SOLE | 0 | 1,105,793 | 0 | 32,301 | |
| CEVA Inc | COM | 157210105 | 4,369 | 146,303 | SH | DFND | 2 | 50,363 | 0 | 95,940 | |
| CEVA Inc | COM | 157210105 | 4,687 | 156,980 | SH | DFND | 1 | 156,980 | 0 | 0 | |
| CEVA Inc | COM | 157210105 | 1,076 | 36,035 | SH | DFND | 3 | 36,035 | 0 | 0 | |
| CEVA Inc | COM | 157210105 | 2,463 | 82,500 | SH | SOLE | 0 | 82,500 | 0 | 0 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 21,285 | 251,057 | SH | DFND | 1 | 251,057 | 0 | 0 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 12,742 | 150,295 | SH | DFND | 2 | 135,072 | 0 | 15,223 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 26,099 | 307,842 | SH | SOLE | 0 | 307,842 | 0 | 0 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 1,645 | 19,402 | SH | DFND | 3 | 12,068 | 0 | 7,334 | |
| CarMax Inc | COM | 143130102 | 4,215 | 47,899 | SH | DFND | 1 | 47,899 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 2,895 | 32,903 | SH | DFND | 3 | 20,331 | 0 | 12,572 | |
| CarMax Inc | COM | 143130102 | 28,455 | 323,357 | SH | DFND | 2 | 323,357 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 4,442 | 50,476 | SH | SOLE | 0 | 50,476 | 0 | 0 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 28,529 | 7,277,771 | SH | DFND | 1 | 7,277,771 | 0 | 0 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 91,100 | 23,239,921 | SH | DFND | 2 | 8,158,260 | 0 | 15,081,661 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 5,164 | 1,317,238 | SH | SOLE | 0 | 1,317,238 | 0 | 0 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 34,587 | 8,823,115 | SH | DFND | 3 | 319,346 | 0 | 8,503,769 | |
| Chegg | COM | 163092109 | 99,259 | 3,314,160 | SH | DFND | 1 | 3,314,160 | 0 | 0 | |
| Chegg | COM | 163092109 | 144,557 | 4,826,621 | SH | DFND | 2 | 2,246,084 | 0 | 2,580,537 | |
| Chegg | COM | 163092109 | 27,166 | 907,033 | SH | DFND | 3 | 687,117 | 0 | 219,916 | |
| Chegg | COM | 163092109 | 89,449 | 2,986,620 | SH | SOLE | 0 | 2,938,847 | 0 | 47,773 | |
| Chewy Inc | CL A | 16679L109 | 42,078 | 1,711,896 | SH | DFND | 1 | 1,711,896 | 0 | 0 | |
| Chewy Inc | CL A | 16679L109 | 40,915 | 1,664,574 | SH | DFND | 2 | 49,517 | 0 | 1,615,057 | |
| Chewy Inc | CL A | 16679L109 | 13,854 | 563,630 | SH | SOLE | 0 | 563,630 | 0 | 0 | |
| Chewy Inc | CL A | 16679L109 | 563 | 22,907 | SH | DFND | 3 | 22,907 | 0 | 0 | |
| Chipotle Mexican Grill | COM | 169656105 | 50,342 | 59,897 | SH | DFND | 1 | 59,897 | 0 | 0 | |
| Chipotle Mexican Grill | COM | 169656105 | 191,604 | 227,972 | SH | DFND | 2 | 173,100 | 0 | 54,872 | |
| Chipotle Mexican Grill | COM | 169656105 | 41,149 | 48,959 | SH | DFND | 3 | 34,089 | 0 | 14,870 | |
| Chipotle Mexican Grill | COM | 169656105 | 120,644 | 143,543 | SH | SOLE | 0 | 139,367 | 0 | 4,176 | |
| CoStar Group | COM | 22160N109 | 105,683 | 178,158 | SH | DFND | 2 | 28,653 | 0 | 149,505 | |
| CoStar Group | COM | 22160N109 | 94,131 | 158,684 | SH | DFND | 1 | 158,684 | 0 | 0 | |
| CoStar Group | COM | 22160N109 | 1,269 | 2,139 | SH | DFND | 3 | 2,139 | 0 | 0 | |
| CoStar Group | COM | 22160N109 | 32,468 | 54,733 | SH | SOLE | 0 | 54,733 | 0 | 0 | |
| Coca Cola | COM | 191216100 | 1,781 | 32,721 | SH | DFND | 2 | 0 | 0 | 32,721 | |
| Coca Cola | COM | 191216100 | 27,327 | 501,973 | SH | DFND | 1 | 501,973 | 0 | 0 | |
| Coca Cola | COM | 191216100 | 35 | 649 | SH | DFND | 3 | 649 | 0 | 0 | |
| Coca Cola | COM | 191216100 | 33,695 | 618,945 | SH | SOLE | 0 | 618,945 | 0 | 0 | |
| Codexis | COM | 192005106 | 15,014 | 1,094,701 | SH | DFND | 2 | 377,803 | 0 | 716,898 | |
| Codexis | COM | 192005106 | 15,422 | 1,124,473 | SH | DFND | 1 | 1,124,473 | 0 | 0 | |
| Codexis | COM | 192005106 | 3,820 | 278,491 | SH | DFND | 3 | 278,491 | 0 | 0 | |
| Codexis | COM | 192005106 | 10,608 | 773,435 | SH | SOLE | 0 | 773,435 | 0 | 0 | |
| Consolidated Edison | COM | 209115104 | 794 | 8,400 | SH | DFND | 1 | 8,400 | 0 | 0 | |
| Copa Holdings S A | CL A | P31076105 | 11,231 | 113,728 | SH | DFND | 1 | 113,728 | 0 | 0 | |
| Copa Holdings S A | CL A | P31076105 | 218,731 | 2,214,993 | SH | DFND | 2 | 1,531,614 | 0 | 683,379 | |
| Copa Holdings S A | CL A | P31076105 | 52,515 | 531,796 | SH | DFND | 3 | 19,482 | 0 | 512,314 | |
| Copa Holdings S A | CL A | P31076105 | 27,436 | 277,829 | SH | SOLE | 0 | 277,829 | 0 | 0 | |
| Credicorp | COM | G2519Y108 | 19,300 | 92,592 | SH | DFND | 1 | 92,592 | 0 | 0 | |
| Credicorp | COM | G2519Y108 | 303,490 | 1,456,007 | SH | DFND | 2 | 803,114 | 0 | 652,893 | |
| Credicorp | COM | G2519Y108 | 25,337 | 121,553 | SH | SOLE | 0 | 121,553 | 0 | 0 | |
| Credicorp | COM | G2519Y108 | 46,540 | 223,277 | SH | DFND | 3 | 7,399 | 0 | 215,878 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 89,049 | 3,040,265 | SH | DFND | 1 | 3,040,265 | 0 | 0 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 917,938 | 31,339,623 | SH | DFND | 2 | 11,303,130 | 0 | 20,036,493 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 72,294 | 2,468,229 | SH | DFND | 3 | 989,323 | 0 | 1,478,906 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 302,066 | 10,312,939 | SH | SOLE | 0 | 8,369,824 | 0 | 1,943,115 | |
| Cullen/Frost Bankers | COM | 229899109 | 8,769 | 99,026 | SH | DFND | 1 | 99,026 | 0 | 0 | |
| Cullen/Frost Bankers | COM | 229899109 | 637 | 7,190 | SH | DFND | 2 | 0 | 0 | 7,190 | |
| Cullen/Frost Bankers | COM | 229899109 | 10,505 | 118,630 | SH | SOLE | 0 | 118,630 | 0 | 0 | |
| Cullen/Frost Bankers | COM | 229899109 | 12 | 131 | SH | DFND | 3 | 131 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 10,990 | 110,100 | SH | DFND | 1 | 110,100 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 11,589 | 116,100 | SH | DFND | 2 | 40,300 | 0 | 75,800 | |
| CyberArk Software Ltd | SHS | M2862V108 | 2,935 | 29,400 | SH | DFND | 3 | 29,400 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 8,036 | 80,500 | SH | SOLE | 0 | 80,500 | 0 | 0 | |
| Denali Therapeutics | COM | 24823R105 | 1,643 | 107,251 | SH | DFND | 3 | 75,474 | 0 | 31,777 | |
| Denali Therapeutics | COM | 24823R105 | 26,614 | 1,737,201 | SH | DFND | 2 | 79,328 | 0 | 1,657,873 | |
| Denali Therapeutics | COM | 24823R105 | 28,896 | 1,886,138 | SH | DFND | 1 | 1,886,138 | 0 | 0 | |
| Denali Therapeutics | COM | 24823R105 | 55,656 | 3,632,873 | SH | SOLE | 0 | 3,632,873 | 0 | 0 | |
| Dexcom Inc | COM | 252131107 | 34,003 | 227,839 | SH | DFND | 3 | 148,839 | 0 | 79,000 | |
| Dexcom Inc | COM | 252131107 | 443,840 | 2,974,003 | SH | DFND | 2 | 1,105,544 | 0 | 1,868,459 | |
| Dexcom Inc | COM | 252131107 | 94,143 | 630,816 | SH | DFND | 1 | 630,816 | 0 | 0 | |
| Dexcom Inc | COM | 252131107 | 148,145 | 992,663 | SH | SOLE | 0 | 530,473 | 0 | 462,190 | |
| Digimarc | COM | 25381B101 | 3,635 | 93,000 | SH | DFND | 1 | 93,000 | 0 | 0 | |
| Digimarc | COM | 25381B101 | 11,039 | 282,390 | SH | DFND | 2 | 98,099 | 0 | 184,291 | |
| Digimarc | COM | 25381B101 | 2,792 | 71,414 | SH | DFND | 3 | 71,414 | 0 | 0 | |
| Digimarc | COM | 25381B101 | 3,186 | 81,500 | SH | SOLE | 0 | 81,500 | 0 | 0 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 7,570 | 117,117 | SH | DFND | 1 | 117,117 | 0 | 0 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 518 | 8,021 | SH | DFND | 2 | 0 | 0 | 8,021 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 10 | 153 | SH | DFND | 3 | 153 | 0 | 0 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 8,864 | 137,125 | SH | SOLE | 0 | 137,125 | 0 | 0 | |
| EOG Resources | COM | 26875P101 | 289,307 | 3,897,961 | SH | DFND | 2 | 3,002,748 | 0 | 895,213 | |
| EOG Resources | COM | 26875P101 | 73,505 | 990,367 | SH | DFND | 1 | 990,367 | 0 | 0 | |
| EOG Resources | COM | 26875P101 | 51,067 | 688,055 | SH | DFND | 3 | 450,677 | 0 | 237,378 | |
| EOG Resources | COM | 26875P101 | 176,658 | 2,380,200 | SH | SOLE | 0 | 2,312,201 | 0 | 67,999 | |
| Ecolab | COM | 278865100 | 6,333 | 31,980 | SH | DFND | 1 | 31,980 | 0 | 0 | |
| Ecolab | COM | 278865100 | 602 | 3,041 | SH | DFND | 3 | 3,041 | 0 | 0 | |
| Ecolab | COM | 278865100 | 6,858 | 34,630 | SH | DFND | 2 | 20,648 | 0 | 13,982 | |
| Edwards Lifesciences Corp | COM | 28176E108 | 276 | 1,256 | SH | DFND | 3 | 1,256 | 0 | 0 | |
| Estee Lauder 'A' | COM | 518439104 | 37,454 | 188,260 | SH | DFND | 2 | 188,260 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 22,924 | 1,294,415 | SH | DFND | 2 | 36,931 | 0 | 1,257,484 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 23,090 | 1,303,782 | SH | DFND | 1 | 1,303,782 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 303 | 17,130 | SH | DFND | 3 | 17,130 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 5,896 | 332,940 | SH | SOLE | 0 | 332,940 | 0 | 0 | |
| Eversource Energy | COM | 30040W108 | 855 | 10,000 | SH | DFND | 1 | 10,000 | 0 | 0 | |
| Evolent Health Inc A | CL A | 30050B101 | 2,493 | 346,733 | SH | DFND | 2 | 119,826 | 0 | 226,907 | |
| Evolent Health Inc A | CL A | 30050B101 | 606 | 84,272 | SH | DFND | 3 | 84,272 | 0 | 0 | |
| Evolent Health Inc A | CL A | 30050B101 | 2,587 | 359,780 | SH | DFND | 1 | 359,780 | 0 | 0 | |
| Evolent Health Inc A | CL A | 30050B101 | 2,108 | 293,216 | SH | SOLE | 0 | 293,216 | 0 | 0 | |
| Exact Sciences | COM | 30063P105 | 17,665 | 195,479 | SH | DFND | 1 | 195,479 | 0 | 0 | |
| Exact Sciences | COM | 30063P105 | 19,223 | 212,712 | SH | DFND | 2 | 73,524 | 0 | 139,188 | |
| Exact Sciences | COM | 30063P105 | 4,943 | 54,693 | SH | DFND | 3 | 54,693 | 0 | 0 | |
| Exact Sciences | COM | 30063P105 | 13,925 | 154,086 | SH | SOLE | 0 | 154,086 | 0 | 0 | |
| Exelon Corporation | COM | 30161N101 | 710 | 14,700 | SH | DFND | 1 | 14,700 | 0 | 0 | |
| Facebook Cl.A | CL A | 30303M102 | 1,525,924 | 8,568,754 | SH | DFND | 2 | 3,628,804 | 0 | 4,939,950 | |
| Facebook Cl.A | CL A | 30303M102 | 408,328 | 2,292,945 | SH | DFND | 1 | 2,292,945 | 0 | 0 | |
| Facebook Cl.A | CL A | 30303M102 | 137,503 | 772,142 | SH | DFND | 3 | 484,831 | 0 | 287,311 | |
| Facebook Cl.A | CL A | 30303M102 | 749,629 | 4,209,508 | SH | SOLE | 0 | 3,172,919 | 0 | 1,036,589 | |
| Farfetch | ORD SHS CL A | 30744W107 | 1,590 | 183,980 | SH | DFND | 1 | 183,980 | 0 | 0 | |
| Farfetch | ORD SHS CL A | 30744W107 | 942 | 109,046 | SH | DFND | 3 | 109,046 | 0 | 0 | |
| Farfetch | ORD SHS CL A | 30744W107 | 8,778 | 1,016,025 | SH | SOLE | 0 | 663,536 | 0 | 352,489 | |
| Faro Technologies | COM | 311642102 | 4,918 | 101,715 | SH | DFND | 1 | 101,715 | 0 | 0 | |
| Faro Technologies | COM | 311642102 | 7,443 | 153,948 | SH | DFND | 2 | 53,517 | 0 | 100,431 | |
| Faro Technologies | COM | 311642102 | 1,940 | 40,132 | SH | DFND | 3 | 40,132 | 0 | 0 | |
| Faro Technologies | COM | 311642102 | 5,216 | 107,880 | SH | SOLE | 0 | 107,880 | 0 | 0 | |
| Fastenal | COM | 311900104 | 15,555 | 476,131 | SH | DFND | 2 | 433,430 | 0 | 42,701 | |
| Fastenal | COM | 311900104 | 23,616 | 722,861 | SH | DFND | 1 | 722,861 | 0 | 0 | |
| Fastenal | COM | 311900104 | 2,603 | 79,676 | SH | DFND | 3 | 49,584 | 0 | 30,092 | |
| Fastenal | COM | 311900104 | 28,495 | 872,209 | SH | SOLE | 0 | 872,209 | 0 | 0 | |
| Ferrari NV | COM | N3167Y103 | 1,786,384 | 11,576,009 | SH | DFND | 2 | 3,490,736 | 0 | 8,085,273 | |
| Ferrari NV | COM | N3167Y103 | 309,099 | 2,003,000 | SH | SOLE | 0 | 2,003,000 | 0 | 0 | |
| Fiat Chrysler Automobiles | SHS | N31738102 | 478,721 | 36,987,296 | SH | DFND | 2 | 11,732,953 | 0 | 25,254,343 | |
| First Republic Bank | COM | 33616C100 | 122,928 | 1,271,230 | SH | DFND | 1 | 1,271,230 | 0 | 0 | |
| First Republic Bank | COM | 33616C100 | 6,532 | 67,551 | SH | DFND | 3 | 47,815 | 0 | 19,736 | |
| First Republic Bank | COM | 33616C100 | 47,070 | 486,759 | SH | SOLE | 0 | 486,759 | 0 | 0 | |
| First Republic Bank | COM | 33616C100 | 149,288 | 1,543,830 | SH | DFND | 2 | 431,426 | 0 | 1,112,404 | |
| Foamix Pharmaceuticals | SHS | M46135105 | 338 | 111,200 | SH | SOLE | 0 | 111,200 | 0 | 0 | |
| Foamix Pharmaceuticals | SHS | M46135105 | 329 | 108,200 | SH | DFND | 1 | 108,200 | 0 | 0 | |
| Fortive Corp | COM | 34959J108 | 19,020 | 277,425 | SH | SOLE | 0 | 277,425 | 0 | 0 | |
| Fortive Corp | COM | 34959J108 | 2,609 | 38,053 | SH | DFND | 3 | 26,905 | 0 | 11,148 | |
| Fortive Corp | COM | 34959J108 | 56,842 | 829,090 | SH | DFND | 2 | 189,612 | 0 | 639,478 | |
| Fortive Corp | COM | 34959J108 | 50,259 | 733,071 | SH | DFND | 1 | 733,071 | 0 | 0 | |
| Glaukos Corp | COM | 377322102 | 75,661 | 1,210,383 | SH | DFND | 1 | 1,210,383 | 0 | 0 | |
| Glaukos Corp | COM | 377322102 | 74,968 | 1,199,290 | SH | DFND | 2 | 90,103 | 0 | 1,109,187 | |
| Glaukos Corp | COM | 377322102 | 1,574 | 25,176 | SH | DFND | 3 | 25,176 | 0 | 0 | |
| Glaukos Corp | COM | 377322102 | 24,488 | 391,741 | SH | SOLE | 0 | 391,741 | 0 | 0 | |
| GrubHub Inc | COM | 400110102 | 149,899 | 2,666,775 | SH | DFND | 1 | 2,666,775 | 0 | 0 | |
| GrubHub Inc | COM | 400110102 | 235,227 | 4,184,789 | SH | DFND | 2 | 1,700,135 | 0 | 2,484,654 | |
| GrubHub Inc | COM | 400110102 | 143,829 | 2,558,771 | SH | SOLE | 0 | 2,519,294 | 0 | 39,477 | |
| GrubHub Inc | COM | 400110102 | 33,336 | 593,069 | SH | DFND | 3 | 447,414 | 0 | 145,655 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 5,246 | 403,569 | SH | DFND | 2 | 71,617 | 0 | 331,952 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 1,318 | 101,389 | SH | DFND | 1 | 101,389 | 0 | 0 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 6,496 | 499,703 | SH | DFND | 3 | 16,779 | 0 | 482,924 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 48,324 | 847,047 | SH | DFND | 2 | 629,117 | 0 | 217,930 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 81,787 | 1,433,604 | SH | SOLE | 0 | 1,433,604 | 0 | 0 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 15,458 | 270,958 | SH | DFND | 3 | 193,278 | 0 | 77,680 | |
| HEICO | COM | 422806109 | 19,102 | 152,960 | SH | DFND | 1 | 152,960 | 0 | 0 | |
| HEICO | COM | 422806109 | 10,942 | 87,619 | SH | SOLE | 0 | 87,619 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 38,094 | 391,467 | SH | DFND | 1 | 391,467 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 71,458 | 734,329 | SH | DFND | 2 | 225,407 | 0 | 508,922 | |
| HEICO 'A' | CL A | 422806208 | 685 | 7,042 | SH | DFND | 3 | 7,042 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 8,003 | 82,246 | SH | SOLE | 0 | 82,246 | 0 | 0 | |
| Health Catalyst Inc | COM | 42225T107 | 79 | 2,492 | SH | DFND | 3 | 2,492 | 0 | 0 | |
| Howard Hughes | COM | 44267D107 | 25,855 | 199,497 | SH | DFND | 1 | 199,497 | 0 | 0 | |
| Howard Hughes | COM | 44267D107 | 67,645 | 521,952 | SH | SOLE | 0 | 507,615 | 0 | 14,337 | |
| Howard Hughes | COM | 44267D107 | 99,037 | 764,174 | SH | DFND | 2 | 570,054 | 0 | 194,120 | |
| Howard Hughes | COM | 44267D107 | 21,818 | 168,352 | SH | DFND | 3 | 117,586 | 0 | 50,766 | |
| Hutchison China Meditech | SPONSORED ADR | 44842L103 | 477 | 26,765 | SH | DFND | 1 | 26,765 | 0 | 0 | |
| Hutchison China Meditech | SPONSORED ADR | 44842L103 | 3,410 | 191,146 | SH | DFND | 3 | 0 | 0 | 191,146 | |
| ICICI Bank ADR | ADR | 45104G104 | 62,423 | 5,125,015 | SH | DFND | 3 | 3,835,423 | 0 | 1,289,592 | |
| ICICI Bank ADR | ADR | 45104G104 | 140,799 | 11,559,861 | SH | DFND | 2 | 8,130,925 | 0 | 3,428,936 | |
| ICICI Bank ADR | ADR | 45104G104 | 115,245 | 9,461,857 | SH | DFND | 1 | 9,461,857 | 0 | 0 | |
| ICICI Bank ADR | ADR | 45104G104 | 189,457 | 15,554,738 | SH | SOLE | 0 | 15,554,738 | 0 | 0 | |
| IPG Photonics Corp | COM | 44980X109 | 3,489 | 25,728 | SH | DFND | 3 | 25,728 | 0 | 0 | |
| IPG Photonics Corp | COM | 44980X109 | 13,709 | 101,102 | SH | DFND | 2 | 34,991 | 0 | 66,111 | |
| IPG Photonics Corp | COM | 44980X109 | 10,841 | 79,947 | SH | DFND | 1 | 79,947 | 0 | 0 | |
| IPG Photonics Corp | COM | 44980X109 | 9,985 | 73,636 | SH | SOLE | 0 | 73,636 | 0 | 0 | |
| Illumina | COM | 452327109 | 496,831 | 1,633,131 | SH | DFND | 1 | 1,633,131 | 0 | 0 | |
| Illumina | COM | 452327109 | 3,105,540 | 10,208,206 | SH | DFND | 2 | 2,941,228 | 0 | 7,266,978 | |
| Illumina | COM | 452327109 | 146,524 | 481,638 | SH | DFND | 3 | 287,556 | 0 | 194,082 | |
| Illumina | COM | 452327109 | 1,501,304 | 4,934,928 | SH | SOLE | 0 | 4,020,119 | 0 | 914,809 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 9,427 | 829,143 | SH | DFND | 1 | 829,143 | 0 | 0 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 3,609 | 317,433 | SH | DFND | 2 | 271,698 | 0 | 45,735 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 2,982 | 262,295 | SH | DFND | 3 | 139,878 | 0 | 122,417 | |
| Interactive Brokers Group | COM | 45841N107 | 90,341 | 1,684,210 | SH | DFND | 1 | 1,684,210 | 0 | 0 | |
| Interactive Brokers Group | COM | 45841N107 | 185,748 | 3,462,866 | SH | DFND | 2 | 1,965,285 | 0 | 1,497,581 | |
| Interactive Brokers Group | COM | 45841N107 | 94,098 | 1,754,253 | SH | SOLE | 0 | 1,716,129 | 0 | 38,124 | |
| Interactive Brokers Group | COM | 45841N107 | 27,646 | 515,398 | SH | DFND | 3 | 360,723 | 0 | 154,675 | |
| Intuitive Surgical | COM NEW | 46120E602 | 105,091 | 194,639 | SH | DFND | 1 | 194,639 | 0 | 0 | |
| Intuitive Surgical | COM NEW | 46120E602 | 638,105 | 1,181,830 | SH | DFND | 2 | 431,270 | 0 | 750,560 | |
| Intuitive Surgical | COM NEW | 46120E602 | 41,720 | 77,270 | SH | DFND | 3 | 43,128 | 0 | 34,142 | |
| Intuitive Surgical | COM NEW | 46120E602 | 348,831 | 646,068 | SH | SOLE | 0 | 444,231 | 0 | 201,837 | |
| Invesco Senior Income Trust | COM | 46131H107 | 12,435 | 2,960,719 | SH | DFND | 1 | 2,960,719 | 0 | 0 | |
| Invesco Senior Income Trust | COM | 46131H107 | 1,313 | 312,581 | SH | DFND | 3 | 312,581 | 0 | 0 | |
| Ionis Pharmaceuticals | COM | 462222100 | 52,671 | 879,167 | SH | DFND | 1 | 879,167 | 0 | 0 | |
| Ionis Pharmaceuticals | COM | 462222100 | 109,083 | 1,820,775 | SH | SOLE | 0 | 905,050 | 0 | 915,725 | |
| Ionis Pharmaceuticals | COM | 462222100 | 20,839 | 347,844 | SH | DFND | 3 | 191,838 | 0 | 156,006 | |
| Ionis Pharmaceuticals | COM | 462222100 | 321,567 | 5,367,503 | SH | DFND | 2 | 1,955,165 | 0 | 3,412,338 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 213,258 | 25,357,618 | SH | DFND | 2 | 12,522,358 | 0 | 12,835,260 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 83,871 | 9,972,783 | SH | DFND | 3 | 362,985 | 0 | 9,609,798 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 17,596 | 2,092,238 | SH | DFND | 1 | 2,092,238 | 0 | 0 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 17,648 | 2,098,498 | SH | SOLE | 0 | 2,098,498 | 0 | 0 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 31,146 | 1,104,082 | SH | DFND | 1 | 1,104,082 | 0 | 0 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 39,893 | 1,414,128 | SH | DFND | 2 | 260,703 | 0 | 1,153,425 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 49,168 | 1,742,927 | SH | DFND | 3 | 110,142 | 0 | 1,632,785 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 9,376 | 332,377 | SH | SOLE | 0 | 332,377 | 0 | 0 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 30,636 | 1,664,991 | SH | DFND | 1 | 1,664,991 | 0 | 0 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 114,296 | 6,211,720 | SH | DFND | 2 | 4,686,109 | 0 | 1,525,611 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 76,680 | 4,167,418 | SH | SOLE | 0 | 4,050,825 | 0 | 116,593 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 25,494 | 1,385,540 | SH | DFND | 3 | 977,195 | 0 | 408,345 | |
| Jianpu Technology Inc- ADR | ADR | 47738D101 | 2,420 | 967,818 | SH | SOLE | 0 | 967,818 | 0 | 0 | |
| Jianpu Technology Inc- ADR | ADR | 47738D101 | 2,793 | 1,117,238 | SH | DFND | 1 | 1,117,238 | 0 | 0 | |
| Jumia Technologies Ag ADR | SPONSORED ADS | 48138M105 | 71,426 | 9,007,098 | SH | DFND | 2 | 1,613,880 | 0 | 7,393,218 | |
| Kaleido Biosciences Inc | COM | 483347100 | 1,856 | 246,500 | SH | DFND | 1 | 246,500 | 0 | 0 | |
| Kaleido Biosciences Inc | COM | 483347100 | 1,457 | 193,500 | SH | SOLE | 0 | 193,500 | 0 | 0 | |
| Kirby | COM | 497266106 | 78,380 | 953,997 | SH | DFND | 1 | 953,997 | 0 | 0 | |
| Kirby | COM | 497266106 | 291,060 | 3,542,601 | SH | DFND | 2 | 2,668,590 | 0 | 874,011 | |
| Kirby | COM | 497266106 | 190,922 | 2,323,788 | SH | SOLE | 0 | 2,257,203 | 0 | 66,585 | |
| Kirby | COM | 497266106 | 63,365 | 771,237 | SH | DFND | 3 | 542,598 | 0 | 228,639 | |
| Korea Electric Power ADR | SPONSORED ADR | 500631106 | 18 | 1,700 | SH | DFND | 2 | 1,700 | 0 | 0 | |
| Korea Electric Power ADR | SPONSORED ADR | 500631106 | 1,025 | 94,600 | SH | DFND | 3 | 94,600 | 0 | 0 | |
| LIBERTY MEDIA CORP | DEB 4.00011/1 | 530715AG6 | 1,268 | 1,708,000 | SH | DFND | 3 | 1,708,000 | 0 | 0 | |
| LIBERTY MEDIA CORP | DEB 4.00011/1 | 530715AG6 | 7 | 9,000 | SH | DFND | 2 | 9,000 | 0 | 0 | |
| LIBERTY MEDIA CORP | DEB 4.00011/1 | 530715AG6 | 19,347 | 26,056,000 | SH | DFND | 1 | 26,056,000 | 0 | 0 | |
| LendingTree | COM | 52603B107 | 116,421 | 375,032 | SH | SOLE | 0 | 367,955 | 0 | 7,077 | |
| LendingTree | COM | 52603B107 | 182,508 | 587,919 | SH | DFND | 2 | 365,377 | 0 | 222,542 | |
| LendingTree | COM | 52603B107 | 46,280 | 149,085 | SH | DFND | 3 | 117,555 | 0 | 31,530 | |
| LendingTree | COM | 52603B107 | 77,731 | 250,398 | SH | DFND | 1 | 250,398 | 0 | 0 | |
| Lindblad Expeditions Holdings | COM | 535219109 | 11,732 | 700,000 | SH | SOLE | 0 | 700,000 | 0 | 0 | |
| Line Corp Sponsored Adr | SPONSORED ADR | 53567X101 | 11,433 | 318,120 | SH | DFND | 2 | 12,867 | 0 | 305,253 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 26,360 | 645,456 | SH | DFND | 1 | 645,456 | 0 | 0 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 1,729 | 42,345 | SH | DFND | 3 | 29,045 | 0 | 13,300 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 38,254 | 936,685 | SH | DFND | 2 | 150,009 | 0 | 786,676 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 77,141 | 1,888,855 | SH | SOLE | 0 | 1,888,855 | 0 | 0 | |
| M&T Bank | COM | 55261F104 | 15,286 | 96,766 | SH | DFND | 2 | 96,766 | 0 | 0 | |
| MRC Global | COM | 55345K103 | 7,884 | 650,000 | SH | SOLE | 0 | 650,000 | 0 | 0 | |
| MakeMyTrip | SHS | V5633W109 | 72,761 | 3,206,722 | SH | DFND | 2 | 2,019,552 | 0 | 1,187,170 | |
| Markel Corp | COM | 570535104 | 312,393 | 264,314 | SH | DFND | 2 | 182,297 | 0 | 82,017 | |
| Markel Corp | COM | 570535104 | 111,405 | 94,259 | SH | DFND | 1 | 94,259 | 0 | 0 | |
| Markel Corp | COM | 570535104 | 56,414 | 47,732 | SH | DFND | 3 | 33,347 | 0 | 14,385 | |
| Markel Corp | COM | 570535104 | 181,068 | 153,201 | SH | SOLE | 0 | 149,369 | 0 | 3,832 | |
| MarketAxess Holdings | COM | 57060D108 | 362,431 | 1,106,660 | SH | DFND | 1 | 1,106,660 | 0 | 0 | |
| MarketAxess Holdings | COM | 57060D108 | 561,462 | 1,714,389 | SH | DFND | 2 | 740,448 | 0 | 973,941 | |
| MarketAxess Holdings | COM | 57060D108 | 73,349 | 223,965 | SH | DFND | 3 | 169,978 | 0 | 53,987 | |
| MarketAxess Holdings | COM | 57060D108 | 278,254 | 849,630 | SH | SOLE | 0 | 837,147 | 0 | 12,483 | |
| Martin Marietta Materials | COM | 573284106 | 95,537 | 348,549 | SH | DFND | 1 | 348,549 | 0 | 0 | |
| Martin Marietta Materials | COM | 573284106 | 234,173 | 854,334 | SH | SOLE | 0 | 830,181 | 0 | 24,153 | |
| Martin Marietta Materials | COM | 573284106 | 76,780 | 280,117 | SH | DFND | 3 | 196,937 | 0 | 83,180 | |
| Martin Marietta Materials | COM | 573284106 | 368,203 | 1,343,315 | SH | DFND | 2 | 1,021,710 | 0 | 321,605 | |
| Masimo Corp | COM | 574795100 | 65 | 438 | SH | DFND | 3 | 438 | 0 | 0 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 771,954 | 2,842,560 | SH | DFND | 2 | 1,780,649 | 0 | 1,061,911 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 125,162 | 460,883 | SH | DFND | 3 | 324,214 | 0 | 136,669 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 317,218 | 1,168,090 | SH | DFND | 1 | 1,168,090 | 0 | 0 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 418,798 | 1,542,137 | SH | SOLE | 0 | 1,504,374 | 0 | 37,763 | |
| McDonald's | COM | 580135101 | 19 | 90 | SH | DFND | 3 | 90 | 0 | 0 | |
| McDonald's | COM | 580135101 | 1,090 | 5,078 | SH | DFND | 2 | 0 | 0 | 5,078 | |
| McDonald's | COM | 580135101 | 15,528 | 72,322 | SH | DFND | 1 | 72,322 | 0 | 0 | |
| McDonald's | COM | 580135101 | 18,701 | 87,101 | SH | SOLE | 0 | 87,101 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 90,560 | 164,288 | SH | DFND | 1 | 164,288 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 94,893 | 172,147 | SH | SOLE | 0 | 172,147 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 126,629 | 229,720 | SH | DFND | 3 | 16,633 | 0 | 213,087 | |
| MercadoLibre | COM | 58733R102 | 2,233,548 | 4,051,934 | SH | DFND | 2 | 1,368,094 | 0 | 2,683,840 | |
| Mettler-Toledo | COM | 592688105 | 73,911 | 104,927 | SH | DFND | 1 | 104,927 | 0 | 0 | |
| Mettler-Toledo | COM | 592688105 | 334,356 | 474,668 | SH | DFND | 2 | 311,530 | 0 | 163,138 | |
| Mettler-Toledo | COM | 592688105 | 1,598 | 2,268 | SH | DFND | 3 | 2,268 | 0 | 0 | |
| Mettler-Toledo | COM | 592688105 | 33,813 | 48,002 | SH | SOLE | 0 | 48,002 | 0 | 0 | |
| Microsoft | COM | 594918104 | 107,061 | 770,060 | SH | DFND | 1 | 770,060 | 0 | 0 | |
| Microsoft | COM | 594918104 | 380,843 | 2,739,286 | SH | DFND | 2 | 2,153,243 | 0 | 586,043 | |
| Microsoft | COM | 594918104 | 70,251 | 505,295 | SH | DFND | 3 | 354,834 | 0 | 150,461 | |
| Microsoft | COM | 594918104 | 234,676 | 1,687,949 | SH | SOLE | 0 | 1,644,725 | 0 | 43,224 | |
| Mobile Telesystems ADR | SPONSORED ADR | 607409109 | 171 | 21,100 | SH | DFND | 1 | 21,100 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 22,429 | 1,408,848 | SH | DFND | 1 | 1,408,848 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 21,373 | 1,342,527 | SH | DFND | 2 | 140,528 | 0 | 1,201,999 | |
| Moderna Inc | COM | 60770K107 | 6,768 | 425,096 | SH | SOLE | 0 | 425,096 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 610 | 38,326 | SH | DFND | 3 | 38,326 | 0 | 0 | |
| Moody's Corp | COM | 615369105 | 145,097 | 708,378 | SH | DFND | 1 | 708,378 | 0 | 0 | |
| Moody's Corp | COM | 615369105 | 569,387 | 2,779,804 | SH | DFND | 2 | 2,118,871 | 0 | 660,933 | |
| Moody's Corp | COM | 615369105 | 119,848 | 585,110 | SH | DFND | 3 | 410,993 | 0 | 174,117 | |
| Moody's Corp | COM | 615369105 | 357,057 | 1,743,189 | SH | SOLE | 0 | 1,693,553 | 0 | 49,636 | |
| Myriad Genetics Inc | COM | 62855J104 | 27,325 | 954,421 | SH | DFND | 3 | 667,681 | 0 | 286,740 | |
| Myriad Genetics Inc | COM | 62855J104 | 33,174 | 1,158,704 | SH | DFND | 1 | 1,158,704 | 0 | 0 | |
| Myriad Genetics Inc | COM | 62855J104 | 123,754 | 4,322,522 | SH | DFND | 2 | 3,260,202 | 0 | 1,062,320 | |
| Myriad Genetics Inc | COM | 62855J104 | 80,398 | 2,808,156 | SH | SOLE | 0 | 2,726,849 | 0 | 81,307 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 3,030 | 1,942,609 | SH | DFND | 3 | 1,084,526 | 0 | 858,083 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 94,548 | 60,607,999 | SH | DFND | 2 | 18,439,796 | 0 | 42,168,203 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 7,841 | 5,026,397 | SH | DFND | 1 | 5,026,397 | 0 | 0 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 50,684 | 32,489,731 | SH | SOLE | 0 | 27,528,325 | 0 | 4,961,406 | |
| NVIDIA | COM | 67066G104 | 45,087 | 259,018 | SH | DFND | 3 | 147,421 | 0 | 111,597 | |
| NVIDIA | COM | 67066G104 | 723,748 | 4,157,798 | SH | DFND | 2 | 1,540,773 | 0 | 2,617,025 | |
| NVIDIA | COM | 67066G104 | 147,067 | 844,872 | SH | DFND | 1 | 844,872 | 0 | 0 | |
| NVIDIA | COM | 67066G104 | 389,762 | 2,239,109 | SH | SOLE | 0 | 1,589,604 | 0 | 649,505 | |
| National Instruments Corp | COM | 636518102 | 13,202 | 314,417 | SH | DFND | 1 | 314,417 | 0 | 0 | |
| National Instruments Corp | COM | 636518102 | 6,546 | 155,893 | SH | DFND | 2 | 49,007 | 0 | 106,886 | |
| National Instruments Corp | COM | 636518102 | 1,537 | 36,613 | SH | DFND | 3 | 36,613 | 0 | 0 | |
| National Instruments Corp | COM | 636518102 | 15,308 | 364,562 | SH | SOLE | 0 | 364,562 | 0 | 0 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 61,405 | 230,689 | SH | DFND | 1 | 230,689 | 0 | 0 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 346,043 | 1,300,033 | SH | DFND | 2 | 465,485 | 0 | 834,548 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 23,034 | 86,537 | SH | DFND | 3 | 47,816 | 0 | 38,721 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 120,004 | 450,838 | SH | SOLE | 0 | 226,756 | 0 | 224,082 | |
| Netflix Inc | COM | 64110L106 | 318,184 | 1,188,941 | SH | DFND | 1 | 1,188,941 | 0 | 0 | |
| Netflix Inc | COM | 64110L106 | 1,029,944 | 3,848,533 | SH | DFND | 2 | 1,476,190 | 0 | 2,372,343 | |
| Netflix Inc | COM | 64110L106 | 631,734 | 2,360,565 | SH | SOLE | 0 | 1,891,121 | 0 | 469,444 | |
| Netflix Inc | COM | 64110L106 | 79,615 | 297,493 | SH | DFND | 3 | 184,201 | 0 | 113,292 | |
| New Relic | COM | 64829B100 | 435 | 7,075 | SH | DFND | 3 | 7,075 | 0 | 0 | |
| New Relic | COM | 64829B100 | 31,619 | 514,556 | SH | DFND | 2 | 15,921 | 0 | 498,635 | |
| New Relic | COM | 64829B100 | 32,845 | 534,505 | SH | DFND | 1 | 534,505 | 0 | 0 | |
| New Relic | COM | 64829B100 | 11,228 | 182,712 | SH | SOLE | 0 | 182,712 | 0 | 0 | |
| Novocure Ltd | ORD SHS | G6674U108 | 36,573 | 489,074 | SH | DFND | 3 | 387,989 | 0 | 101,085 | |
| Novocure Ltd | ORD SHS | G6674U108 | 269,728 | 3,606,957 | SH | DFND | 2 | 1,396,047 | 0 | 2,210,910 | |
| Novocure Ltd | ORD SHS | G6674U108 | 192,414 | 2,573,069 | SH | DFND | 1 | 2,573,069 | 0 | 0 | |
| Novocure Ltd | ORD SHS | G6674U108 | 148,402 | 1,984,518 | SH | SOLE | 0 | 1,952,959 | 0 | 31,559 | |
| Now Inc/DE | COM | 67011P100 | 40,589 | 3,538,751 | SH | DFND | 1 | 3,538,751 | 0 | 0 | |
| Now Inc/DE | COM | 67011P100 | 84,719 | 7,386,158 | SH | DFND | 2 | 4,023,781 | 0 | 3,362,377 | |
| Now Inc/DE | COM | 67011P100 | 11,471 | 1,000,124 | SH | DFND | 3 | 734,940 | 0 | 265,184 | |
| Now Inc/DE | COM | 67011P100 | 50,169 | 4,373,930 | SH | SOLE | 0 | 4,296,024 | 0 | 77,906 | |
| Nucana Plc ADR | SPONSORED ADR | 67022C106 | 2,433 | 336,100 | SH | SOLE | 0 | 336,100 | 0 | 0 | |
| Nucana Plc ADR | SPONSORED ADR | 67022C106 | 3,556 | 491,208 | SH | DFND | 1 | 491,208 | 0 | 0 | |
| Nuveen Senior Income Fund | COM | 67067Y104 | 2,174 | 376,702 | SH | DFND | 1 | 376,702 | 0 | 0 | |
| Orchard Therapeutics PLC ADR | ADS | 68570P101 | 10,989 | 925,000 | SH | SOLE | 0 | 925,000 | 0 | 0 | |
| Pacira BioSciences | COM | 695127100 | 12,432 | 326,557 | SH | DFND | 2 | 125,283 | 0 | 201,274 | |
| Pacira BioSciences | COM | 695127100 | 14,902 | 391,439 | SH | DFND | 1 | 391,439 | 0 | 0 | |
| Pacira BioSciences | COM | 695127100 | 5,209 | 136,831 | SH | DFND | 3 | 114,240 | 0 | 22,591 | |
| Pacira BioSciences | COM | 695127100 | 11,302 | 296,883 | SH | SOLE | 0 | 296,883 | 0 | 0 | |
| Peloton Interactive Inc | CL A COM | 70614W100 | 19,439 | 774,444 | SH | DFND | 1 | 774,444 | 0 | 0 | |
| Peloton Interactive Inc | CL A COM | 70614W100 | 108,511 | 4,323,147 | SH | DFND | 2 | 1,570,803 | 0 | 2,752,344 | |
| Peloton Interactive Inc | CL A COM | 70614W100 | 37,730 | 1,503,184 | SH | SOLE | 0 | 711,950 | 0 | 791,234 | |
| Peloton Interactive Inc | CL A COM | 70614W100 | 6,226 | 248,046 | SH | DFND | 3 | 114,392 | 0 | 133,654 | |
| Penumbra Inc | COM | 70975L107 | 61,629 | 458,241 | SH | DFND | 1 | 458,241 | 0 | 0 | |
| Penumbra Inc | COM | 70975L107 | 2,924 | 21,740 | SH | DFND | 3 | 21,740 | 0 | 0 | |
| Penumbra Inc | COM | 70975L107 | 58,713 | 436,558 | SH | DFND | 2 | 32,137 | 0 | 404,421 | |
| Penumbra Inc | COM | 70975L107 | 23,613 | 175,576 | SH | SOLE | 0 | 175,576 | 0 | 0 | |
| Pepsico | COM | 713448108 | 1,470 | 10,720 | SH | DFND | 2 | 0 | 0 | 10,720 | |
| Pepsico | COM | 713448108 | 21,769 | 158,781 | SH | DFND | 1 | 158,781 | 0 | 0 | |
| Pepsico | COM | 713448108 | 28 | 206 | SH | DFND | 3 | 206 | 0 | 0 | |
| Pepsico | COM | 713448108 | 26,519 | 193,430 | SH | SOLE | 0 | 193,430 | 0 | 0 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 60,882 | 4,207,439 | SH | DFND | 1 | 4,207,439 | 0 | 0 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 317,682 | 21,954,553 | SH | DFND | 2 | 6,808,161 | 0 | 15,146,392 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 11,930 | 824,446 | SH | SOLE | 0 | 824,446 | 0 | 0 | |
| Petrobras Pref ADR | SP ADR NON VTG | 71654V101 | 7,964 | 606,122 | SH | DFND | 1 | 606,122 | 0 | 0 | |
| Petrobras Pref ADR | SP ADR NON VTG | 71654V101 | 52,512 | 3,996,317 | SH | DFND | 2 | 1,594,186 | 0 | 2,402,131 | |
| Pinduoduo Inc ADR | SPONSORED ADS | 722304102 | 49,873 | 1,547,875 | SH | DFND | 1 | 1,547,875 | 0 | 0 | |
| Pinduoduo Inc ADR | SPONSORED ADS | 722304102 | 290,587 | 9,018,828 | SH | DFND | 2 | 3,254,603 | 0 | 5,764,225 | |
| Pinduoduo Inc ADR | SPONSORED ADS | 722304102 | 167,454 | 5,197,217 | SH | SOLE | 0 | 3,639,255 | 0 | 1,557,962 | |
| Pinduoduo Inc ADR | SPONSORED ADS | 722304102 | 20,133 | 624,862 | SH | DFND | 3 | 364,091 | 0 | 260,771 | |
| Pioneer Floating Rate Trust | COM | 72369J102 | 5,697 | 541,036 | SH | DFND | 1 | 541,036 | 0 | 0 | |
| Procter & Gamble | COM | 742718109 | 26,077 | 209,658 | SH | DFND | 1 | 209,658 | 0 | 0 | |
| Procter & Gamble | COM | 742718109 | 34 | 274 | SH | DFND | 3 | 274 | 0 | 0 | |
| Procter & Gamble | COM | 742718109 | 1,796 | 14,442 | SH | DFND | 2 | 0 | 0 | 14,442 | |
| Procter & Gamble | COM | 742718109 | 32,318 | 259,836 | SH | SOLE | 0 | 259,836 | 0 | 0 | |
| Redfin | COM | 75737F108 | 2,141 | 127,129 | SH | DFND | 3 | 89,908 | 0 | 37,221 | |
| Redfin | COM | 75737F108 | 39,382 | 2,338,608 | SH | DFND | 2 | 99,897 | 0 | 2,238,711 | |
| Redfin | COM | 75737F108 | 41,709 | 2,476,809 | SH | DFND | 1 | 2,476,809 | 0 | 0 | |
| Redfin | COM | 75737F108 | 15,977 | 948,724 | SH | SOLE | 0 | 948,724 | 0 | 0 | |
| ResMed | COM | 761152107 | 80,581 | 596,413 | SH | DFND | 1 | 596,413 | 0 | 0 | |
| ResMed | COM | 761152107 | 196,131 | 1,451,642 | SH | SOLE | 0 | 1,410,688 | 0 | 40,954 | |
| ResMed | COM | 761152107 | 299,507 | 2,216,761 | SH | DFND | 2 | 1,672,816 | 0 | 543,945 | |
| ResMed | COM | 761152107 | 64,723 | 479,042 | SH | DFND | 3 | 336,298 | 0 | 142,744 | |
| ResTORbio Inc | COM | 76133L103 | 5,783 | 654,147 | SH | DFND | 1 | 654,147 | 0 | 0 | |
| ResTORbio Inc | COM | 76133L103 | 5,456 | 617,240 | SH | SOLE | 0 | 617,240 | 0 | 0 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 28,315 | 709,653 | SH | DFND | 3 | 497,464 | 0 | 212,189 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 207,194 | 5,192,843 | SH | DFND | 2 | 3,949,850 | 0 | 1,242,993 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 34,203 | 857,226 | SH | DFND | 1 | 857,226 | 0 | 0 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 83,720 | 2,098,245 | SH | SOLE | 0 | 2,038,547 | 0 | 59,698 | |
| Ritchie Bros. Auctioneers | COM | 767744105 | 51,836 | 1,299,592 | SH | DFND | 2 | 743,628 | 0 | 555,964 | |
| Ritchie Bros. Auctioneers | COM | 767744105 | 17,308 | 433,928 | SH | SOLE | 0 | 433,928 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 96,539 | 948,690 | SH | DFND | 1 | 948,690 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 95,240 | 935,930 | SH | DFND | 2 | 28,603 | 0 | 907,327 | |
| Roku | COM CL A | 77543R102 | 1,286 | 12,635 | SH | DFND | 3 | 12,635 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 33,651 | 330,688 | SH | SOLE | 0 | 330,688 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 3,539 | 450,800 | SH | DFND | 1 | 450,800 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 28,100 | 3,579,565 | SH | SOLE | 0 | 3,579,565 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 356 | 45,392 | SH | DFND | 3 | 45,392 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 1,295 | 165,010 | SH | DFND | 2 | 57,732 | 0 | 107,278 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 452,665 | 6,819,293 | SH | DFND | 2 | 4,932,924 | 0 | 1,886,369 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 3,910 | 58,898 | SH | DFND | 3 | 7,082 | 0 | 51,816 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 3,334 | 50,222 | SH | SOLE | 0 | 50,222 | 0 | 0 | |
| SEA Ltd ADR | ADR | 81141R100 | 19,313 | 624,017 | SH | DFND | 1 | 624,017 | 0 | 0 | |
| SEA Ltd ADR | ADR | 81141R100 | 21,179 | 684,293 | SH | DFND | 2 | 0 | 0 | 684,293 | |
| SEA Ltd ADR | ADR | 81141R100 | 19,842 | 641,104 | SH | SOLE | 0 | 641,104 | 0 | 0 | |
| SINA Corp | ORD | G81477104 | 5,155 | 131,550 | SH | DFND | 3 | 0 | 0 | 131,550 | |
| SOLARCITY CORP | NOTE 1.625 11/0 | 83416TAC4 | 32,159 | 32,240,000 | SH | DFND | 1 | 32,240,000 | 0 | 0 | |
| SOLARCITY CORP | NOTE 1.625 11/0 | 83416TAC4 | 7 | 7,000 | SH | DFND | 2 | 7,000 | 0 | 0 | |
| SOLARCITY CORP | NOTE 1.625 11/0 | 83416TAC4 | 6,123 | 6,139,000 | SH | DFND | 3 | 6,139,000 | 0 | 0 | |
| SUNPOWER CORP | DBCV 4.000 1/1 | 867652AL3 | 750 | 817,000 | SH | DFND | 3 | 817,000 | 0 | 0 | |
| SUNPOWER CORP | DBCV 4.000 1/1 | 867652AL3 | 4,693 | 5,113,000 | SH | DFND | 1 | 5,113,000 | 0 | 0 | |
| Sage Therapeutics Inc | COM | 78667J108 | 69 | 490 | SH | DFND | 3 | 490 | 0 | 0 | |
| Salesforce.com | COM | 79466L302 | 80,060 | 539,345 | SH | DFND | 1 | 539,345 | 0 | 0 | |
| Salesforce.com | COM | 79466L302 | 31,661 | 213,289 | SH | DFND | 3 | 118,782 | 0 | 94,507 | |
| Salesforce.com | COM | 79466L302 | 485,918 | 3,273,501 | SH | DFND | 2 | 1,198,273 | 0 | 2,075,228 | |
| Salesforce.com | COM | 79466L302 | 165,061 | 1,111,973 | SH | SOLE | 0 | 553,388 | 0 | 558,585 | |
| Schlumberger | COM | 806857108 | 3,777 | 110,529 | SH | DFND | 2 | 110,529 | 0 | 0 | |
| Seattle Genetics | COM | 812578102 | 74,956 | 877,704 | SH | DFND | 1 | 877,704 | 0 | 0 | |
| Seattle Genetics | COM | 812578102 | 256,951 | 3,008,792 | SH | DFND | 2 | 2,233,386 | 0 | 775,406 | |
| Seattle Genetics | COM | 812578102 | 55,532 | 650,259 | SH | DFND | 3 | 462,469 | 0 | 187,790 | |
| Seattle Genetics | COM | 812578102 | 172,892 | 2,024,497 | SH | SOLE | 0 | 1,970,579 | 0 | 53,918 | |
| Service Corp.Intl. | COM | 817565104 | 56,585 | 1,183,536 | SH | DFND | 3 | 830,155 | 0 | 353,381 | |
| Service Corp.Intl. | COM | 817565104 | 259,704 | 5,431,999 | SH | DFND | 2 | 4,094,667 | 0 | 1,337,332 | |
| Service Corp.Intl. | COM | 817565104 | 70,521 | 1,475,016 | SH | DFND | 1 | 1,475,016 | 0 | 0 | |
| Service Corp.Intl. | COM | 817565104 | 169,186 | 3,538,707 | SH | SOLE | 0 | 3,438,078 | 0 | 100,629 | |
| Severstal GDR Reg S | COM | 818150302 | 148 | 10,286 | SH | DFND | 1 | 10,286 | 0 | 0 | |
| Sherwin-Williams Co | COM | 824348106 | 10,769 | 19,584 | SH | DFND | 2 | 19,584 | 0 | 0 | |
| ShockWave Medical Inc | COM | 82489T104 | 27 | 891 | SH | DFND | 3 | 891 | 0 | 0 | |
| Shopify 'A' | CL A | 82509L107 | 74,783 | 239,950 | SH | DFND | 3 | 157,871 | 0 | 82,079 | |
| Shopify 'A' | CL A | 82509L107 | 1,038,709 | 3,332,827 | SH | DFND | 2 | 1,534,637 | 0 | 1,798,190 | |
| Shopify 'A' | CL A | 82509L107 | 353,558 | 1,134,435 | SH | DFND | 1 | 1,134,435 | 0 | 0 | |
| Shopify 'A' | CL A | 82509L107 | 420,677 | 1,349,794 | SH | SOLE | 0 | 1,129,735 | 0 | 220,059 | |
| SiteOne Landscape Supply | COM | 82982L103 | 37,118 | 501,463 | SH | DFND | 1 | 501,463 | 0 | 0 | |
| SiteOne Landscape Supply | COM | 82982L103 | 135,333 | 1,828,325 | SH | DFND | 2 | 1,380,504 | 0 | 447,821 | |
| SiteOne Landscape Supply | COM | 82982L103 | 29,451 | 397,885 | SH | DFND | 3 | 280,196 | 0 | 117,689 | |
| SiteOne Landscape Supply | COM | 82982L103 | 88,952 | 1,201,728 | SH | SOLE | 0 | 1,167,538 | 0 | 34,190 | |
| Slack Technologies Inc | COM CL A | 83088V102 | 8,098 | 341,276 | SH | DFND | 2 | 0 | 0 | 341,276 | |
| Snap Inc | CL A | 83304A106 | 2,926 | 185,160 | SH | DFND | 2 | 185,160 | 0 | 0 | |
| Sohu.com | COM | 83410S108 | 2,033 | 200,140 | SH | DFND | 3 | 0 | 0 | 200,140 | |
| Spectrum Brands Holdings Inc | COM | 84790A105 | 2,194 | 41,624 | SH | DFND | 1 | 41,624 | 0 | 0 | |
| Spectrum Brands Holdings Inc | COM | 84790A105 | 8,186 | 155,276 | SH | DFND | 2 | 112,219 | 0 | 43,057 | |
| Spectrum Brands Holdings Inc | COM | 84790A105 | 1,826 | 34,632 | SH | DFND | 3 | 24,425 | 0 | 10,207 | |
| Spectrum Brands Holdings Inc | COM | 84790A105 | 5,492 | 104,174 | SH | SOLE | 0 | 101,260 | 0 | 2,914 | |
| Splunk Inc | COM | 848637104 | 11,897 | 100,940 | SH | DFND | 1 | 100,940 | 0 | 0 | |
| Splunk Inc | COM | 848637104 | 15,464 | 131,210 | SH | DFND | 2 | 45,515 | 0 | 85,695 | |
| Splunk Inc | COM | 848637104 | 8,708 | 73,884 | SH | SOLE | 0 | 73,884 | 0 | 0 | |
| Splunk Inc | COM | 848637104 | 3,919 | 33,255 | SH | DFND | 3 | 33,255 | 0 | 0 | |
| Spotify Technology SA | SHS | L8681T102 | 133,938 | 1,174,895 | SH | DFND | 1 | 1,174,895 | 0 | 0 | |
| Spotify Technology SA | SHS | L8681T102 | 47,356 | 415,403 | SH | DFND | 3 | 260,258 | 0 | 155,145 | |
| Spotify Technology SA | SHS | L8681T102 | 1,573,940 | 13,806,495 | SH | DFND | 2 | 5,566,872 | 0 | 8,239,623 | |
| Spotify Technology SA | SHS | L8681T102 | 425,694 | 3,734,154 | SH | SOLE | 0 | 3,095,231 | 0 | 638,923 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 18,645 | 723,242 | SH | DFND | 1 | 723,242 | 0 | 0 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 13,324 | 516,817 | SH | DFND | 2 | 194,243 | 0 | 322,574 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 12,169 | 472,038 | SH | SOLE | 0 | 472,038 | 0 | 0 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 5,058 | 196,191 | SH | DFND | 3 | 168,583 | 0 | 27,608 | |
| Stericycle Inc | COM | 858912108 | 34,273 | 672,937 | SH | DFND | 1 | 672,937 | 0 | 0 | |
| Stericycle Inc | COM | 858912108 | 123,586 | 2,426,587 | SH | DFND | 2 | 1,836,715 | 0 | 589,872 | |
| Stericycle Inc | COM | 858912108 | 27,526 | 540,476 | SH | DFND | 3 | 379,145 | 0 | 161,331 | |
| Stericycle Inc | COM | 858912108 | 82,602 | 1,621,879 | SH | SOLE | 0 | 1,576,692 | 0 | 45,187 | |
| Stitch Fix | COM CL A | 860897107 | 37,228 | 1,933,936 | SH | DFND | 1 | 1,933,936 | 0 | 0 | |
| Stitch Fix | COM CL A | 860897107 | 35,790 | 1,859,245 | SH | DFND | 2 | 56,782 | 0 | 1,802,463 | |
| Stitch Fix | COM CL A | 860897107 | 12,776 | 663,676 | SH | SOLE | 0 | 663,676 | 0 | 0 | |
| Stitch Fix | COM CL A | 860897107 | 501 | 26,002 | SH | DFND | 3 | 26,002 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 4,821 | 226,300 | SH | DFND | 1 | 226,300 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 7,611 | 357,255 | SH | DFND | 2 | 123,627 | 0 | 233,628 | |
| Stratasys | SHS | M85548101 | 1,906 | 89,452 | SH | DFND | 3 | 89,452 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 3,081 | 144,600 | SH | SOLE | 0 | 144,600 | 0 | 0 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 26,329 | 768,946 | SH | DFND | 3 | 423,868 | 0 | 345,078 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 1,353,366 | 39,525,883 | SH | DFND | 2 | 9,853,096 | 0 | 29,672,787 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 67,296 | 1,965,413 | SH | DFND | 1 | 1,965,413 | 0 | 0 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 138,028 | 4,031,189 | SH | SOLE | 0 | 2,017,491 | 0 | 2,013,698 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 43,893 | 939,896 | SH | DFND | 1 | 939,896 | 0 | 0 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 173,259 | 3,710,037 | SH | DFND | 2 | 2,907,054 | 0 | 802,983 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 34,613 | 741,181 | SH | DFND | 3 | 516,687 | 0 | 224,494 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 101,563 | 2,174,795 | SH | SOLE | 0 | 2,114,054 | 0 | 60,741 | |
| TJX Companies | COM | 872540109 | 1,702 | 30,526 | SH | DFND | 3 | 18,959 | 0 | 11,567 | |
| TJX Companies | COM | 872540109 | 23,444 | 420,588 | SH | DFND | 2 | 409,336 | 0 | 11,252 | |
| TJX Companies | COM | 872540109 | 11,387 | 204,293 | SH | DFND | 1 | 204,293 | 0 | 0 | |
| TJX Companies | COM | 872540109 | 5,515 | 98,943 | SH | SOLE | 0 | 98,943 | 0 | 0 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 94,843 | 2,040,507 | SH | DFND | 1 | 2,040,507 | 0 | 0 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 854,486 | 18,383,940 | SH | DFND | 2 | 11,157,258 | 0 | 7,226,682 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 66,385 | 1,428,245 | SH | DFND | 3 | 1,023,514 | 0 | 404,731 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 207,487 | 4,464,000 | SH | SOLE | 0 | 4,345,229 | 0 | 118,771 | |
| Tandem Diabetes Care | COM NEW | 875372203 | 13,276 | 225,100 | SH | DFND | 1 | 225,100 | 0 | 0 | |
| Tandem Diabetes Care | COM NEW | 875372203 | 12,362 | 209,600 | SH | SOLE | 0 | 209,600 | 0 | 0 | |
| Targa Resources | COM | 87612G101 | 104 | 2,599 | SH | DFND | 1 | 2,599 | 0 | 0 | |
| Teladoc | COM | 87918A105 | 46,353 | 684,473 | SH | DFND | 1 | 684,473 | 0 | 0 | |
| Teladoc | COM | 87918A105 | 112,102 | 1,655,376 | SH | DFND | 2 | 1,118,690 | 0 | 536,686 | |
| Teladoc | COM | 87918A105 | 25,304 | 373,651 | SH | DFND | 3 | 287,620 | 0 | 86,031 | |
| Teladoc | COM | 87918A105 | 70,686 | 1,043,800 | SH | SOLE | 0 | 1,019,160 | 0 | 24,640 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 5,612 | 439,438 | SH | DFND | 1 | 439,438 | 0 | 0 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 180,946 | 14,169,631 | SH | DFND | 2 | 9,253,188 | 0 | 4,916,443 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 19,097 | 1,495,469 | SH | SOLE | 0 | 1,495,469 | 0 | 0 | |
| Teradyne | COM | 880770102 | 49,665 | 857,617 | SH | DFND | 1 | 857,617 | 0 | 0 | |
| Teradyne | COM | 880770102 | 274,937 | 4,747,661 | SH | DFND | 2 | 3,964,093 | 0 | 783,568 | |
| Teradyne | COM | 880770102 | 41,545 | 717,407 | SH | DFND | 3 | 503,101 | 0 | 214,306 | |
| Teradyne | COM | 880770102 | 120,459 | 2,080,111 | SH | SOLE | 0 | 2,020,018 | 0 | 60,093 | |
| TerraForm Power | CL A COM | 88104R209 | 38,916 | 2,135,300 | SH | DFND | 1 | 2,135,300 | 0 | 0 | |
| TerraForm Power | CL A COM | 88104R209 | 43 | 2,360 | SH | DFND | 2 | 2,360 | 0 | 0 | |
| TerraForm Power | CL A COM | 88104R209 | 1,868 | 102,503 | SH | DFND | 3 | 102,503 | 0 | 0 | |
| Tesla Inc | COM | 88160R101 | 370,115 | 1,536,576 | SH | DFND | 1 | 1,536,576 | 0 | 0 | |
| Tesla Inc | COM | 88160R101 | 1,843,158 | 7,652,086 | SH | DFND | 2 | 2,221,255 | 0 | 5,430,831 | |
| Tesla Inc | COM | 88160R101 | 91,519 | 379,951 | SH | DFND | 3 | 256,500 | 0 | 123,451 | |
| Tesla Inc | COM | 88160R101 | 935,288 | 3,882,958 | SH | SOLE | 0 | 3,252,932 | 0 | 630,026 | |
| The Trade Desk | COM CL A | 88339J105 | 155,887 | 831,176 | SH | DFND | 1 | 831,176 | 0 | 0 | |
| The Trade Desk | COM CL A | 88339J105 | 111,691 | 595,524 | SH | SOLE | 0 | 585,673 | 0 | 9,851 | |
| The Trade Desk | COM CL A | 88339J105 | 25,423 | 135,554 | SH | DFND | 3 | 96,932 | 0 | 38,622 | |
| The Trade Desk | COM CL A | 88339J105 | 219,646 | 1,171,133 | SH | DFND | 2 | 427,548 | 0 | 743,585 | |
| Thermo Fisher Scientific | COM | 883556102 | 82,198 | 282,205 | SH | DFND | 1 | 282,205 | 0 | 0 | |
| Thermo Fisher Scientific | COM | 883556102 | 316,395 | 1,086,261 | SH | DFND | 2 | 824,901 | 0 | 261,360 | |
| Thermo Fisher Scientific | COM | 883556102 | 66,967 | 229,914 | SH | DFND | 3 | 161,296 | 0 | 68,618 | |
| Thermo Fisher Scientific | COM | 883556102 | 203,616 | 699,063 | SH | SOLE | 0 | 679,197 | 0 | 19,866 | |
| Trupanion | COM | 898202106 | 2,130 | 83,801 | SH | DFND | 3 | 83,801 | 0 | 0 | |
| Trupanion | COM | 898202106 | 8,349 | 328,461 | SH | DFND | 2 | 113,638 | 0 | 214,823 | |
| Trupanion | COM | 898202106 | 5,023 | 197,600 | SH | DFND | 1 | 197,600 | 0 | 0 | |
| Trupanion | COM | 898202106 | 18,684 | 735,000 | SH | SOLE | 0 | 735,000 | 0 | 0 | |
| United Parcel Service | CL B | 911312106 | 17,958 | 149,876 | SH | DFND | 1 | 149,876 | 0 | 0 | |
| United Parcel Service | CL B | 911312106 | 1,191 | 9,940 | SH | DFND | 2 | 0 | 0 | 9,940 | |
| United Parcel Service | CL B | 911312106 | 23 | 190 | SH | DFND | 3 | 190 | 0 | 0 | |
| United Parcel Service | CL B | 911312106 | 21,474 | 179,216 | SH | SOLE | 0 | 179,216 | 0 | 0 | |
| Unity Biotechnology Inc | COM | 91381U101 | 1,513 | 248,000 | SH | DFND | 1 | 248,000 | 0 | 0 | |
| Unity Biotechnology Inc | COM | 91381U101 | 21,686 | 3,555,014 | SH | SOLE | 0 | 3,555,014 | 0 | 0 | |
| Upwork Inc | COM | 91688F104 | 6,308 | 474,100 | SH | DFND | 1 | 474,100 | 0 | 0 | |
| Upwork Inc | COM | 91688F104 | 5,643 | 424,100 | SH | DFND | 2 | 145,900 | 0 | 278,200 | |
| Upwork Inc | COM | 91688F104 | 1,404 | 105,500 | SH | DFND | 3 | 105,500 | 0 | 0 | |
| Upwork Inc | COM | 91688F104 | 3,990 | 299,900 | SH | SOLE | 0 | 299,900 | 0 | 0 | |
| Uxin ADR | ADS | 91818X108 | 2,968 | 1,211,500 | SH | DFND | 1 | 1,211,500 | 0 | 0 | |
| Uxin ADR | ADS | 91818X108 | 1,383 | 564,600 | SH | SOLE | 0 | 564,600 | 0 | 0 | |
| Vale SA ADR | ADR | 91912E105 | 32,276 | 2,806,600 | SH | DFND | 1 | 2,806,600 | 0 | 0 | |
| Vale SA ADR | ADR | 91912E105 | 259,292 | 22,547,100 | SH | DFND | 2 | 7,714,200 | 0 | 14,832,900 | |
| Varian Medical Systems Inc | COM | 92220P105 | 8,627 | 72,439 | SH | DFND | 2 | 72,439 | 0 | 0 | |
| Veeco Instruments | COM | 922417100 | 6,854 | 586,854 | SH | DFND | 1 | 586,854 | 0 | 0 | |
| Veeco Instruments | COM | 922417100 | 2,647 | 226,597 | SH | DFND | 2 | 75,504 | 0 | 151,093 | |
| Veeco Instruments | COM | 922417100 | 635 | 54,328 | SH | DFND | 3 | 54,328 | 0 | 0 | |
| Verisk Analytics | COM | 92345Y106 | 12,553 | 79,376 | SH | DFND | 2 | 79,376 | 0 | 0 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 126,973 | 738,174 | SH | DFND | 1 | 738,174 | 0 | 0 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 474,415 | 2,758,069 | SH | DFND | 2 | 2,084,307 | 0 | 673,762 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 101,952 | 592,709 | SH | DFND | 3 | 415,853 | 0 | 176,856 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 305,623 | 1,776,773 | SH | SOLE | 0 | 1,726,071 | 0 | 50,702 | |
| Voya Prime Rate Trust | SH BEN INT | 92913A100 | 2,689 | 571,000 | SH | DFND | 1 | 571,000 | 0 | 0 | |
| Voya Prime Rate Trust | SH BEN INT | 92913A100 | 911 | 193,400 | SH | DFND | 3 | 193,400 | 0 | 0 | |
| WEC Energy Group | COM | 92939U106 | 884 | 9,300 | SH | DFND | 1 | 9,300 | 0 | 0 | |
| Wabtec | COM | 929740108 | 138,263 | 1,924,054 | SH | DFND | 2 | 1,487,991 | 0 | 436,063 | |
| Wabtec | COM | 929740108 | 28,398 | 395,183 | SH | DFND | 3 | 275,458 | 0 | 119,725 | |
| Wabtec | COM | 929740108 | 35,697 | 496,757 | SH | DFND | 1 | 496,757 | 0 | 0 | |
| Wabtec | COM | 929740108 | 82,526 | 1,148,427 | SH | SOLE | 0 | 1,114,988 | 0 | 33,439 | |
| Waters | COM | 941848103 | 69,147 | 309,755 | SH | DFND | 1 | 309,755 | 0 | 0 | |
| Waters | COM | 941848103 | 262,476 | 1,175,810 | SH | DFND | 2 | 903,115 | 0 | 272,695 | |
| Waters | COM | 941848103 | 56,333 | 252,356 | SH | DFND | 3 | 176,127 | 0 | 76,229 | |
| Waters | COM | 941848103 | 160,607 | 719,469 | SH | SOLE | 0 | 698,705 | 0 | 20,764 | |
| Watsco Inc | COM | 942622200 | 101,248 | 598,466 | SH | DFND | 2 | 126,532 | 0 | 471,934 | |
| Watsco Inc | COM | 942622200 | 101,767 | 601,529 | SH | DFND | 1 | 601,529 | 0 | 0 | |
| Watsco Inc | COM | 942622200 | 4,100 | 24,236 | SH | DFND | 3 | 17,581 | 0 | 6,655 | |
| Watsco Inc | COM | 942622200 | 47,826 | 282,691 | SH | SOLE | 0 | 282,691 | 0 | 0 | |
| Wayfair Inc Class A | CL A | 94419L101 | 181,981 | 1,623,091 | SH | DFND | 1 | 1,623,091 | 0 | 0 | |
| Wayfair Inc Class A | CL A | 94419L101 | 179,722 | 1,602,944 | SH | DFND | 2 | 140,080 | 0 | 1,462,864 | |
| Wayfair Inc Class A | CL A | 94419L101 | 13,163 | 117,402 | SH | DFND | 3 | 104,712 | 0 | 12,690 | |
| Wayfair Inc Class A | CL A | 94419L101 | 72,415 | 645,874 | SH | SOLE | 0 | 645,874 | 0 | 0 | |
| Wheaton Precious Metals | COM | 962879102 | 139 | 5,310 | SH | DFND | 1 | 5,310 | 0 | 0 | |
| Wipro Ltd ADR | SPON ADR 1 SH | 97651M109 | 575 | 157,565 | SH | DFND | 2 | 100,842 | 0 | 56,723 | |
| Wix Com | SHS | M98068105 | 285,757 | 2,447,806 | SH | DFND | 2 | 713,104 | 0 | 1,734,702 | |
| Workday Inc | CL A | 98138H101 | 74,130 | 436,162 | SH | DFND | 1 | 436,162 | 0 | 0 | |
| Workday Inc | CL A | 98138H101 | 452,157 | 2,660,372 | SH | DFND | 2 | 969,211 | 0 | 1,691,161 | |
| Workday Inc | CL A | 98138H101 | 29,683 | 174,645 | SH | DFND | 3 | 97,655 | 0 | 76,990 | |
| Workday Inc | CL A | 98138H101 | 296,695 | 1,745,675 | SH | SOLE | 0 | 1,290,343 | 0 | 455,332 | |
| Xylem | COM | 98419M100 | 7,512 | 94,344 | SH | DFND | 1 | 94,344 | 0 | 0 | |
| Xylem | COM | 98419M100 | 714 | 8,968 | SH | DFND | 3 | 8,968 | 0 | 0 | |
| Xylem | COM | 98419M100 | 8,145 | 102,297 | SH | DFND | 2 | 60,980 | 0 | 41,317 | |
| Yext Inc | COM | 98585N106 | 63,093 | 3,970,625 | SH | DFND | 1 | 3,970,625 | 0 | 0 | |
| Yext Inc | COM | 98585N106 | 29,313 | 1,844,719 | SH | SOLE | 0 | 1,844,719 | 0 | 0 | |
| Yext Inc | COM | 98585N106 | 5,405 | 340,132 | SH | DFND | 3 | 311,357 | 0 | 28,775 | |
| Yext Inc | COM | 98585N106 | 55,574 | 3,497,427 | SH | DFND | 2 | 415,460 | 0 | 3,081,967 | |
| Zai Lab ADR | ADR | 98887Q104 | 26,207 | 810,100 | SH | DFND | 1 | 810,100 | 0 | 0 | |
| Zai Lab ADR | ADR | 98887Q104 | 58,550 | 1,809,900 | SH | DFND | 2 | 790,700 | 0 | 1,019,200 | |
| Zai Lab ADR | ADR | 98887Q104 | 6,519 | 201,500 | SH | DFND | 3 | 75,800 | 0 | 125,700 | |
| Zai Lab ADR | ADR | 98887Q104 | 10,177 | 314,600 | SH | SOLE | 0 | 314,600 | 0 | 0 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 29,171 | 987,352 | SH | DFND | 1 | 987,352 | 0 | 0 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 52,130 | 1,764,413 | SH | DFND | 2 | 658,582 | 0 | 1,105,831 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 2,701 | 91,435 | SH | DFND | 3 | 67,465 | 0 | 23,970 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 19,332 | 654,330 | SH | SOLE | 0 | 649,924 | 0 | 4,406 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 61,533 | 2,063,469 | SH | DFND | 1 | 2,063,469 | 0 | 0 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 98,428 | 3,300,734 | SH | SOLE | 0 | 3,216,325 | 0 | 84,409 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 34,816 | 1,167,555 | SH | DFND | 3 | 877,042 | 0 | 290,513 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 147,275 | 4,938,784 | SH | DFND | 2 | 3,279,657 | 0 | 1,659,127 | |
| Zoom Video Communications Inc | CL A | 98980L101 | 22,860 | 300,000 | SH | SOLE | 0 | 300,000 | 0 | 0 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 1,312 | 87,156 | SH | DFND | 3 | 87,156 | 0 | 0 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 5,164 | 343,122 | SH | DFND | 2 | 118,638 | 0 | 224,484 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 7,287 | 484,179 | SH | DFND | 1 | 484,179 | 0 | 0 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 3,692 | 245,311 | SH | SOLE | 0 | 245,311 | 0 | 0 | |
| iRobot | COM | 462726100 | 9,333 | 151,338 | SH | DFND | 1 | 151,338 | 0 | 0 | |
| iRobot | COM | 462726100 | 20,335 | 329,739 | SH | SOLE | 0 | 329,739 | 0 | 0 | |
| iRobot | COM | 462726100 | 4,563 | 73,998 | SH | DFND | 3 | 65,198 | 0 | 8,800 | |
| iRobot | COM | 462726100 | 12,899 | 209,159 | SH | DFND | 2 | 77,071 | 0 | 132,088 | |