The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
|
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
|
||||||||||||||||
| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2U | COM | 90214J101 | 52,868 | 746,190 | SH | DFND | 1 | 746,190 | 0 | 0 | |
| 2U | COM | 90214J101 | 18,411 | 259,856 | SH | SOLE | 0 | 259,856 | 0 | 0 | |
| 2U | COM | 90214J101 | 233 | 3,294 | SH | DFND | 3 | 3,294 | 0 | 0 | |
| 2U | COM | 90214J101 | 29,512 | 416,546 | SH | DFND | 2 | 22,609 | 0 | 393,937 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 44,198 | 672,923 | SH | DFND | 1 | 672,923 | 0 | 0 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 94,107 | 1,432,817 | SH | SOLE | 0 | 1,387,283 | 0 | 45,534 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 32,132 | 489,215 | SH | DFND | 3 | 338,721 | 0 | 150,494 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 143,220 | 2,180,579 | SH | DFND | 2 | 1,652,557 | 0 | 528,022 | |
| AJ Gallagher & Co | COM | 363576109 | 250,296 | 3,204,814 | SH | DFND | 2 | 2,420,488 | 0 | 784,326 | |
| AJ Gallagher & Co | COM | 363576109 | 87,402 | 1,119,106 | SH | DFND | 1 | 1,119,106 | 0 | 0 | |
| AJ Gallagher & Co | COM | 363576109 | 54,375 | 696,222 | SH | DFND | 3 | 480,408 | 0 | 215,814 | |
| AJ Gallagher & Co | COM | 363576109 | 169,810 | 2,174,263 | SH | SOLE | 0 | 2,107,866 | 0 | 66,397 | |
| Abiomed | COM | 003654100 | 102,702 | 359,613 | SH | DFND | 2 | 97,891 | 0 | 261,722 | |
| Abiomed | COM | 003654100 | 149,096 | 522,063 | SH | DFND | 1 | 522,063 | 0 | 0 | |
| Abiomed | COM | 003654100 | 2,948 | 10,323 | SH | DFND | 3 | 10,323 | 0 | 0 | |
| Abiomed | COM | 003654100 | 54,100 | 189,432 | SH | SOLE | 0 | 189,432 | 0 | 0 | |
| Acacia Reasearch Corp | ACACIA TCH COM | 003881307 | 468 | 143,640 | SH | DFND | 1 | 143,640 | 0 | 0 | |
| Acacia Reasearch Corp | ACACIA TCH COM | 003881307 | 724 | 222,180 | SH | SOLE | 0 | 222,180 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 30,994 | 680,741 | SH | DFND | 1 | 680,741 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 40,606 | 891,842 | SH | DFND | 2 | 339,573 | 0 | 552,269 | |
| Activision Blizzard Inc | COM | 00507V109 | 135 | 2,957 | SH | DFND | 3 | 2,957 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 9,764 | 214,453 | SH | SOLE | 0 | 214,453 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 7,398 | 1,720,555 | SH | DFND | 1 | 1,720,555 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 3,013 | 700,697 | SH | SOLE | 0 | 700,697 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 1,261 | 293,226 | SH | DFND | 3 | 293,226 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 4,836 | 1,124,712 | SH | DFND | 2 | 366,703 | 0 | 758,009 | |
| Aduro Biotechnology | COM | 00739L101 | 6,798 | 1,708,037 | SH | DFND | 1 | 1,708,037 | 0 | 0 | |
| Aduro Biotechnology | COM | 00739L101 | 4,849 | 1,218,384 | SH | DFND | 2 | 393,696 | 0 | 824,688 | |
| Aduro Biotechnology | COM | 00739L101 | 1,272 | 319,712 | SH | DFND | 3 | 319,712 | 0 | 0 | |
| Aduro Biotechnology | COM | 00739L101 | 2,329 | 585,293 | SH | SOLE | 0 | 585,293 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 19,820 | 289,717 | SH | DFND | 1 | 289,717 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 15,017 | 219,516 | SH | DFND | 2 | 70,783 | 0 | 148,733 | |
| Aerovironment | COM | 008073108 | 15,089 | 220,567 | SH | SOLE | 0 | 220,567 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 3,874 | 56,629 | SH | DFND | 3 | 56,629 | 0 | 0 | |
| Agios Pharmaceuticals | COM | 00847X104 | 254 | 3,759 | SH | DFND | 3 | 3,759 | 0 | 0 | |
| Agios Pharmaceuticals | COM | 00847X104 | 30,926 | 458,577 | SH | DFND | 1 | 458,577 | 0 | 0 | |
| Agios Pharmaceuticals | COM | 00847X104 | 17,146 | 254,247 | SH | DFND | 2 | 13,817 | 0 | 240,430 | |
| Agios Pharmaceuticals | COM | 00847X104 | 10,496 | 155,642 | SH | SOLE | 0 | 155,642 | 0 | 0 | |
| Albemarle Corp | COM | 012653101 | 36,537 | 445,687 | SH | DFND | 1 | 445,687 | 0 | 0 | |
| Albemarle Corp | COM | 012653101 | 93,588 | 1,141,590 | SH | DFND | 2 | 868,456 | 0 | 273,134 | |
| Albemarle Corp | COM | 012653101 | 67,127 | 818,817 | SH | SOLE | 0 | 796,599 | 0 | 22,218 | |
| Albemarle Corp | COM | 012653101 | 19,168 | 233,810 | SH | DFND | 3 | 162,759 | 0 | 71,051 | |
| Alector Inc | COM | 014442107 | 41 | 2,185 | SH | DFND | 3 | 2,185 | 0 | 0 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 663,862 | 3,638,599 | SH | DFND | 1 | 3,638,599 | 0 | 0 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 6,028,146 | 33,039,987 | SH | DFND | 2 | 12,919,786 | 0 | 20,120,201 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 456,927 | 2,504,393 | SH | DFND | 3 | 793,135 | 0 | 1,711,258 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 1,796,234 | 9,845,077 | SH | SOLE | 0 | 8,205,567 | 0 | 1,639,510 | |
| Align Technology Inc | COM | 016255101 | 2,467 | 8,677 | SH | DFND | 2 | 8,677 | 0 | 0 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 133,475 | 1,428,303 | SH | DFND | 1 | 1,428,303 | 0 | 0 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 152,969 | 1,636,909 | SH | SOLE | 0 | 1,611,723 | 0 | 25,186 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 37,292 | 399,061 | SH | DFND | 3 | 312,915 | 0 | 86,146 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 207,481 | 2,220,231 | SH | DFND | 2 | 1,292,157 | 0 | 928,074 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 2,368 | 2,012 | SH | DFND | 3 | 2,012 | 0 | 0 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 34,887 | 29,643 | SH | DFND | 2 | 26,162 | 0 | 3,481 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 27,629 | 23,476 | SH | DFND | 1 | 23,476 | 0 | 0 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 93,151 | 79,150 | SH | SOLE | 0 | 79,150 | 0 | 0 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 435,265 | 370,972 | SH | DFND | 1 | 370,972 | 0 | 0 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 747,086 | 636,734 | SH | SOLE | 0 | 504,227 | 0 | 132,507 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 139,515 | 118,907 | SH | DFND | 3 | 73,379 | 0 | 45,528 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 1,377,471 | 1,174,004 | SH | DFND | 2 | 560,559 | 0 | 613,445 | |
| Amazon.Com | COM | 023135106 | 911,983 | 512,134 | SH | DFND | 1 | 512,134 | 0 | 0 | |
| Amazon.Com | COM | 023135106 | 4,349,697 | 2,442,621 | SH | DFND | 2 | 766,424 | 0 | 1,676,197 | |
| Amazon.Com | COM | 023135106 | 256,284 | 143,919 | SH | DFND | 3 | 86,625 | 0 | 57,294 | |
| Amazon.Com | COM | 023135106 | 2,331,837 | 1,309,469 | SH | SOLE | 0 | 1,113,104 | 0 | 196,365 | |
| Ambarella | SHS | G037AX101 | 6,372 | 147,500 | SH | DFND | 1 | 147,500 | 0 | 0 | |
| Ambarella | SHS | G037AX101 | 5,129 | 118,734 | SH | DFND | 2 | 38,117 | 0 | 80,617 | |
| Ambarella | SHS | G037AX101 | 4,217 | 97,605 | SH | SOLE | 0 | 97,605 | 0 | 0 | |
| Ambarella | SHS | G037AX101 | 1,321 | 30,571 | SH | DFND | 3 | 30,571 | 0 | 0 | |
| Ameren | COM | 023608102 | 24,567 | 334,013 | SH | DFND | 1 | 334,013 | 0 | 0 | |
| Ameren | COM | 023608102 | 35 | 470 | SH | DFND | 2 | 470 | 0 | 0 | |
| Ameren | COM | 023608102 | 1,074 | 14,602 | SH | DFND | 3 | 14,602 | 0 | 0 | |
| American Express | COM | 025816109 | 18,151 | 166,066 | SH | DFND | 2 | 166,066 | 0 | 0 | |
| American Express | COM | 025816109 | 588 | 5,377 | SH | DFND | 3 | 5,377 | 0 | 0 | |
| American Express | COM | 025816109 | 3,601 | 32,946 | SH | SOLE | 0 | 32,946 | 0 | 0 | |
| American Express | COM | 025816109 | 3,547 | 32,449 | SH | DFND | 1 | 32,449 | 0 | 0 | |
| Analog Devices | COM | 032654105 | 19,086 | 181,306 | SH | SOLE | 0 | 181,306 | 0 | 0 | |
| Analog Devices | COM | 032654105 | 18,762 | 178,227 | SH | DFND | 1 | 178,227 | 0 | 0 | |
| Analog Devices | COM | 032654105 | 1,555 | 14,772 | SH | DFND | 2 | 0 | 0 | 14,772 | |
| Anaplan Inc Common | COM | 03272L108 | 73,668 | 1,871,644 | SH | SOLE | 0 | 1,871,644 | 0 | 0 | |
| Annaly Capital Man. | COM | 035710409 | 177 | 17,762 | SH | DFND | 1 | 17,762 | 0 | 0 | |
| Anthem Inc | COM | 036752103 | 127,914 | 445,725 | SH | DFND | 3 | 307,530 | 0 | 138,195 | |
| Anthem Inc | COM | 036752103 | 575,984 | 2,007,053 | SH | DFND | 2 | 1,512,795 | 0 | 494,258 | |
| Anthem Inc | COM | 036752103 | 180,510 | 628,997 | SH | DFND | 1 | 628,997 | 0 | 0 | |
| Anthem Inc | COM | 036752103 | 385,504 | 1,343,313 | SH | SOLE | 0 | 1,301,294 | 0 | 42,019 | |
| Apache Corp | COM | 037411105 | 125,556 | 3,622,511 | SH | DFND | 1 | 3,622,511 | 0 | 0 | |
| Apache Corp | COM | 037411105 | 374,399 | 10,802,047 | SH | DFND | 2 | 8,108,534 | 0 | 2,693,513 | |
| Apache Corp | COM | 037411105 | 74,240 | 2,141,945 | SH | DFND | 3 | 1,393,526 | 0 | 748,419 | |
| Apache Corp | COM | 037411105 | 253,340 | 7,309,294 | SH | SOLE | 0 | 7,085,970 | 0 | 223,324 | |
| Apollo Commercial Real Estate Finance REIT | COM | 03762U105 | 220 | 12,100 | SH | DFND | 1 | 12,100 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 8,392 | 243,739 | SH | DFND | 1 | 243,739 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 9,768 | 283,700 | SH | DFND | 2 | 91,157 | 0 | 192,543 | |
| Appian Corp | CL A | 03782L101 | 2,528 | 73,431 | SH | DFND | 3 | 73,431 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 6,557 | 190,433 | SH | SOLE | 0 | 190,433 | 0 | 0 | |
| Apple | COM | 037833100 | 1,055 | 5,552 | SH | DFND | 2 | 0 | 0 | 5,552 | |
| Apple | COM | 037833100 | 12,548 | 66,057 | SH | DFND | 1 | 66,057 | 0 | 0 | |
| Apple | COM | 037833100 | 12,867 | 67,738 | SH | SOLE | 0 | 67,738 | 0 | 0 | |
| Aslan Pharmaceuticals ADR | ADS | 04522R101 | 653 | 157,248 | SH | SOLE | 0 | 157,248 | 0 | 0 | |
| Aslan Pharmaceuticals ADR | ADS | 04522R101 | 1,183 | 284,946 | SH | DFND | 1 | 284,946 | 0 | 0 | |
| Atlassian Corp Plc | CL A | G06242104 | 537,785 | 4,784,991 | SH | DFND | 2 | 1,717,540 | 0 | 3,067,451 | |
| Atlassian Corp Plc | CL A | G06242104 | 87,151 | 775,432 | SH | DFND | 1 | 775,432 | 0 | 0 | |
| Atlassian Corp Plc | CL A | G06242104 | 26,115 | 232,362 | SH | DFND | 3 | 97,691 | 0 | 134,671 | |
| Atlassian Corp Plc | CL A | G06242104 | 193,286 | 1,719,782 | SH | SOLE | 0 | 857,898 | 0 | 861,884 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 47,833 | 455,028 | SH | DFND | 1 | 455,028 | 0 | 0 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 159,820 | 1,520,354 | SH | DFND | 2 | 1,152,540 | 0 | 367,814 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 35,610 | 338,758 | SH | DFND | 3 | 232,998 | 0 | 105,760 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 108,429 | 1,031,476 | SH | SOLE | 0 | 999,837 | 0 | 31,639 | |
| Avangrid | COM | 05351W103 | 23,252 | 461,800 | SH | DFND | 1 | 461,800 | 0 | 0 | |
| Avangrid | COM | 05351W103 | 1,045 | 20,764 | SH | DFND | 3 | 20,764 | 0 | 0 | |
| Avangrid | COM | 05351W103 | 33 | 650 | SH | DFND | 2 | 650 | 0 | 0 | |
| Axogen Inc | COM | 05463X106 | 7,563 | 359,100 | SH | DFND | 1 | 359,100 | 0 | 0 | |
| Axogen Inc | COM | 05463X106 | 7,537 | 357,900 | SH | DFND | 2 | 115,000 | 0 | 242,900 | |
| Axogen Inc | COM | 05463X106 | 1,982 | 94,100 | SH | DFND | 3 | 94,100 | 0 | 0 | |
| Axogen Inc | COM | 05463X106 | 3,572 | 169,600 | SH | SOLE | 0 | 169,600 | 0 | 0 | |
| Axon Enterprise Inc | COM | 05464C101 | 8,624 | 158,500 | SH | DFND | 1 | 158,500 | 0 | 0 | |
| Axon Enterprise Inc | COM | 05464C101 | 2,566 | 47,163 | SH | DFND | 3 | 47,163 | 0 | 0 | |
| Axon Enterprise Inc | COM | 05464C101 | 9,894 | 181,842 | SH | DFND | 2 | 58,609 | 0 | 123,233 | |
| Axon Enterprise Inc | COM | 05464C101 | 5,555 | 102,100 | SH | SOLE | 0 | 102,100 | 0 | 0 | |
| BRF SA-ADR | SPONSORED ADR | 10552T107 | 14,492 | 2,490,026 | SH | DFND | 1 | 2,490,026 | 0 | 0 | |
| BRF SA-ADR | SPONSORED ADR | 10552T107 | 103,243 | 17,739,330 | SH | DFND | 2 | 6,250,750 | 0 | 11,488,580 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 155,290 | 942,010 | SH | DFND | 1 | 942,010 | 0 | 0 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 2,114,464 | 12,826,591 | SH | DFND | 2 | 4,483,999 | 0 | 8,342,592 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 94,673 | 574,299 | SH | DFND | 3 | 236,116 | 0 | 338,183 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 524,084 | 3,179,158 | SH | SOLE | 0 | 2,570,275 | 0 | 608,883 | |
| BanColombia Pref ADR | SPON ADR PREF | 05968L102 | 43,152 | 845,117 | SH | DFND | 2 | 0 | 0 | 845,117 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 27,198 | 2,492,980 | SH | DFND | 1 | 2,492,980 | 0 | 0 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 180,741 | 16,566,588 | SH | DFND | 2 | 6,721,424 | 0 | 9,845,164 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 24,573 | 2,252,304 | SH | DFND | 3 | 2,151,179 | 0 | 101,125 | |
| Banco Macro ADR | SPON ADR B | 05961W105 | 4,658 | 101,802 | SH | DFND | 1 | 101,802 | 0 | 0 | |
| Banco Macro ADR | SPON ADR B | 05961W105 | 19,509 | 426,331 | SH | DFND | 2 | 240,165 | 0 | 186,166 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 19,757 | 475,608 | SH | DFND | 1 | 475,608 | 0 | 0 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 13,601 | 327,429 | SH | DFND | 2 | 105,787 | 0 | 221,642 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 3,512 | 84,533 | SH | DFND | 3 | 84,533 | 0 | 0 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 10,090 | 242,900 | SH | SOLE | 0 | 242,900 | 0 | 0 | |
| Beigene Ltd | SPONSORED ADR | 07725L102 | 2,200 | 16,670 | SH | DFND | 1 | 16,670 | 0 | 0 | |
| Beigene Ltd | SPONSORED ADR | 07725L102 | 10,415 | 78,904 | SH | DFND | 3 | 0 | 0 | 78,904 | |
| Benefitfocus Inc | COM | 08180D106 | 15,175 | 306,448 | SH | DFND | 1 | 306,448 | 0 | 0 | |
| Benefitfocus Inc | COM | 08180D106 | 11,210 | 226,368 | SH | SOLE | 0 | 226,368 | 0 | 0 | |
| Benefitfocus Inc | COM | 08180D106 | 3,628 | 73,258 | SH | DFND | 3 | 73,258 | 0 | 0 | |
| Benefitfocus Inc | COM | 08180D106 | 12,732 | 257,105 | SH | DFND | 2 | 65,008 | 0 | 192,097 | |
| BitAuto Holdings Ltd - ADR | SPONSORED ADS | 091727107 | 868 | 54,492 | SH | SOLE | 0 | 54,492 | 0 | 0 | |
| BlackRock Floating Rate Income | COM | 091941104 | 9,794 | 802,170 | SH | DFND | 1 | 802,170 | 0 | 0 | |
| Blackline | COM | 09239B109 | 12,168 | 262,705 | SH | DFND | 1 | 262,705 | 0 | 0 | |
| Blackline | COM | 09239B109 | 9,370 | 202,284 | SH | DFND | 2 | 64,759 | 0 | 137,525 | |
| Blackline | COM | 09239B109 | 2,402 | 51,862 | SH | DFND | 3 | 51,862 | 0 | 0 | |
| Blackline | COM | 09239B109 | 6,447 | 139,175 | SH | SOLE | 0 | 139,175 | 0 | 0 | |
| Blue Apron Holdings Inc | CL A | 09523Q101 | 2,183 | 2,227,600 | SH | DFND | 1 | 2,227,600 | 0 | 0 | |
| Blue Capital Reinsurance Holdings Fund (USD) | COM | G1190F107 | 4,242 | 629,438 | SH | DFND | 1 | 629,438 | 0 | 0 | |
| Bluebird Bio Inc | COM | 09609G100 | 56,215 | 357,309 | SH | DFND | 1 | 357,309 | 0 | 0 | |
| Bluebird Bio Inc | COM | 09609G100 | 346,157 | 2,200,199 | SH | DFND | 2 | 784,042 | 0 | 1,416,157 | |
| Bluebird Bio Inc | COM | 09609G100 | 16,885 | 107,320 | SH | DFND | 3 | 45,376 | 0 | 61,944 | |
| Bluebird Bio Inc | COM | 09609G100 | 285,440 | 1,814,273 | SH | SOLE | 0 | 1,416,208 | 0 | 398,065 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 350 | 8,382 | SH | DFND | 2 | 0 | 0 | 8,382 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 4,218 | 101,110 | SH | DFND | 1 | 101,110 | 0 | 0 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 4,067 | 97,492 | SH | SOLE | 0 | 97,492 | 0 | 0 | |
| CEVA Inc | COM | 157210105 | 3,798 | 140,869 | SH | DFND | 2 | 44,929 | 0 | 95,940 | |
| CEVA Inc | COM | 157210105 | 4,232 | 156,980 | SH | DFND | 1 | 156,980 | 0 | 0 | |
| CEVA Inc | COM | 157210105 | 1,009 | 37,417 | SH | DFND | 3 | 37,417 | 0 | 0 | |
| CEVA Inc | COM | 157210105 | 2,224 | 82,500 | SH | SOLE | 0 | 82,500 | 0 | 0 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 23,645 | 271,817 | SH | DFND | 1 | 271,817 | 0 | 0 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 12,971 | 149,110 | SH | DFND | 2 | 129,975 | 0 | 19,135 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 23,548 | 270,698 | SH | SOLE | 0 | 270,698 | 0 | 0 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 513 | 5,892 | SH | DFND | 3 | 5,892 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 4,614 | 66,100 | SH | DFND | 1 | 66,100 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 771 | 11,046 | SH | DFND | 3 | 11,046 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 21,982 | 314,935 | SH | DFND | 2 | 314,935 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 4,533 | 64,942 | SH | SOLE | 0 | 64,942 | 0 | 0 | |
| Celgene | COM | 151020104 | 100 | 1,057 | SH | DFND | 2 | 1,057 | 0 | 0 | |
| Celgene | COM | 151020104 | 3,348 | 35,491 | SH | DFND | 1 | 35,491 | 0 | 0 | |
| Celgene | COM | 151020104 | 559 | 5,926 | SH | DFND | 3 | 5,926 | 0 | 0 | |
| Celgene | COM | 151020104 | 3,389 | 35,924 | SH | SOLE | 0 | 35,924 | 0 | 0 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 97,059 | 20,917,871 | SH | DFND | 2 | 6,736,297 | 0 | 14,181,574 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 28,229 | 6,083,877 | SH | DFND | 1 | 6,083,877 | 0 | 0 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 30,410 | 6,553,927 | SH | DFND | 3 | 180,746 | 0 | 6,373,181 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 6,404 | 1,380,155 | SH | SOLE | 0 | 1,380,155 | 0 | 0 | |
| Chegg | COM | 163092109 | 161,719 | 4,242,378 | SH | DFND | 2 | 2,158,916 | 0 | 2,083,462 | |
| Chegg | COM | 163092109 | 129,611 | 3,400,067 | SH | DFND | 1 | 3,400,067 | 0 | 0 | |
| Chegg | COM | 163092109 | 29,668 | 778,274 | SH | DFND | 3 | 612,436 | 0 | 165,838 | |
| Chegg | COM | 163092109 | 122,590 | 3,215,906 | SH | SOLE | 0 | 3,164,908 | 0 | 50,998 | |
| China Rapid Finance ADR | SPONSORED ADR | 16953Q105 | 333 | 300,000 | SH | SOLE | 0 | 300,000 | 0 | 0 | |
| Chipotle Mexican Grill | COM | 169656105 | 51,537 | 72,556 | SH | DFND | 1 | 72,556 | 0 | 0 | |
| Chipotle Mexican Grill | COM | 169656105 | 163,436 | 230,091 | SH | DFND | 2 | 174,719 | 0 | 55,372 | |
| Chipotle Mexican Grill | COM | 169656105 | 36,018 | 50,708 | SH | DFND | 3 | 34,923 | 0 | 15,785 | |
| Chipotle Mexican Grill | COM | 169656105 | 104,929 | 147,723 | SH | SOLE | 0 | 142,912 | 0 | 4,811 | |
| CoStar Group | COM | 22160N109 | 73,935 | 158,517 | SH | DFND | 1 | 158,517 | 0 | 0 | |
| CoStar Group | COM | 22160N109 | 51,922 | 111,320 | SH | DFND | 2 | 28,660 | 0 | 82,660 | |
| CoStar Group | COM | 22160N109 | 25,352 | 54,354 | SH | SOLE | 0 | 54,354 | 0 | 0 | |
| CoStar Group | COM | 22160N109 | 326 | 698 | SH | DFND | 3 | 698 | 0 | 0 | |
| Coca Cola | COM | 191216100 | 22,673 | 483,845 | SH | SOLE | 0 | 483,845 | 0 | 0 | |
| Coca Cola | COM | 191216100 | 1,835 | 39,166 | SH | DFND | 2 | 0 | 0 | 39,166 | |
| Coca Cola | COM | 191216100 | 22,355 | 477,054 | SH | DFND | 1 | 477,054 | 0 | 0 | |
| Codexis | COM | 192005106 | 5,640 | 274,739 | SH | DFND | 3 | 274,739 | 0 | 0 | |
| Codexis | COM | 192005106 | 21,735 | 1,058,708 | SH | DFND | 2 | 341,810 | 0 | 716,898 | |
| Codexis | COM | 192005106 | 23,085 | 1,124,473 | SH | DFND | 1 | 1,124,473 | 0 | 0 | |
| Codexis | COM | 192005106 | 12,311 | 599,635 | SH | SOLE | 0 | 599,635 | 0 | 0 | |
| Consolidated Edison | COM | 209115104 | 27,915 | 329,148 | SH | DFND | 1 | 329,148 | 0 | 0 | |
| Consolidated Edison | COM | 209115104 | 23 | 270 | SH | DFND | 2 | 270 | 0 | 0 | |
| Consolidated Edison | COM | 209115104 | 1,616 | 19,056 | SH | DFND | 3 | 19,056 | 0 | 0 | |
| Copa Holdings S A | CL A | P31076105 | 8,505 | 105,514 | SH | DFND | 1 | 105,514 | 0 | 0 | |
| Copa Holdings S A | CL A | P31076105 | 179,948 | 2,232,329 | SH | DFND | 2 | 1,550,967 | 0 | 681,362 | |
| Copa Holdings S A | CL A | P31076105 | 43,716 | 542,311 | SH | DFND | 3 | 15,044 | 0 | 527,267 | |
| Copa Holdings S A | CL A | P31076105 | 22,396 | 277,829 | SH | SOLE | 0 | 277,829 | 0 | 0 | |
| Credicorp | COM | G2519Y108 | 20,112 | 83,816 | SH | DFND | 1 | 83,816 | 0 | 0 | |
| Credicorp | COM | G2519Y108 | 27,953 | 116,497 | SH | SOLE | 0 | 116,497 | 0 | 0 | |
| Credicorp | COM | G2519Y108 | 50,817 | 211,783 | SH | DFND | 3 | 5,722 | 0 | 206,061 | |
| Credicorp | COM | G2519Y108 | 388,261 | 1,618,090 | SH | DFND | 2 | 795,861 | 0 | 822,229 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 140,061 | 3,205,784 | SH | DFND | 1 | 3,205,784 | 0 | 0 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 1,384,635 | 31,692,264 | SH | DFND | 2 | 11,460,411 | 0 | 20,231,853 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 102,534 | 2,346,844 | SH | DFND | 3 | 825,423 | 0 | 1,521,421 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 466,561 | 10,678,890 | SH | SOLE | 0 | 8,563,939 | 0 | 2,114,951 | |
| Cullen/Frost Bankers | COM | 229899109 | 8,247 | 84,964 | SH | DFND | 1 | 84,964 | 0 | 0 | |
| Cullen/Frost Bankers | COM | 229899109 | 673 | 6,932 | SH | DFND | 2 | 0 | 0 | 6,932 | |
| Cullen/Frost Bankers | COM | 229899109 | 8,281 | 85,312 | SH | SOLE | 0 | 85,312 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 13,322 | 111,900 | SH | DFND | 2 | 36,100 | 0 | 75,800 | |
| CyberArk Software Ltd | SHS | M2862V108 | 3,452 | 29,000 | SH | DFND | 3 | 29,000 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 13,107 | 110,100 | SH | DFND | 1 | 110,100 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 9,584 | 80,500 | SH | SOLE | 0 | 80,500 | 0 | 0 | |
| Denali Therapeutics | COM | 24823R105 | 229 | 9,876 | SH | DFND | 3 | 9,876 | 0 | 0 | |
| Denali Therapeutics | COM | 24823R105 | 22,643 | 975,165 | SH | DFND | 2 | 52,668 | 0 | 922,497 | |
| Denali Therapeutics | COM | 24823R105 | 40,968 | 1,764,354 | SH | DFND | 1 | 1,764,354 | 0 | 0 | |
| Denali Therapeutics | COM | 24823R105 | 81,568 | 3,512,831 | SH | SOLE | 0 | 3,512,831 | 0 | 0 | |
| Dexcom Inc | COM | 252131107 | 22,629 | 189,996 | SH | DFND | 3 | 110,996 | 0 | 79,000 | |
| Dexcom Inc | COM | 252131107 | 362,382 | 3,042,673 | SH | DFND | 2 | 1,094,224 | 0 | 1,948,449 | |
| Dexcom Inc | COM | 252131107 | 72,596 | 609,539 | SH | DFND | 1 | 609,539 | 0 | 0 | |
| Dexcom Inc | COM | 252131107 | 128,332 | 1,077,516 | SH | SOLE | 0 | 574,425 | 0 | 503,091 | |
| Digimarc | COM | 25381B101 | 2,918 | 93,000 | SH | DFND | 1 | 93,000 | 0 | 0 | |
| Digimarc | COM | 25381B101 | 8,540 | 272,144 | SH | DFND | 2 | 87,853 | 0 | 184,291 | |
| Digimarc | COM | 25381B101 | 2,230 | 71,070 | SH | DFND | 3 | 71,070 | 0 | 0 | |
| Digimarc | COM | 25381B101 | 2,557 | 81,500 | SH | SOLE | 0 | 81,500 | 0 | 0 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 7,420 | 117,829 | SH | DFND | 1 | 117,829 | 0 | 0 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 611 | 9,697 | SH | DFND | 2 | 0 | 0 | 9,697 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 7,442 | 118,182 | SH | SOLE | 0 | 118,182 | 0 | 0 | |
| EOG Resources | COM | 26875P101 | 225,371 | 2,367,837 | SH | DFND | 2 | 1,841,929 | 0 | 525,908 | |
| EOG Resources | COM | 26875P101 | 62,643 | 658,152 | SH | DFND | 1 | 658,152 | 0 | 0 | |
| EOG Resources | COM | 26875P101 | 39,948 | 419,710 | SH | DFND | 3 | 271,918 | 0 | 147,792 | |
| EOG Resources | COM | 26875P101 | 131,265 | 1,379,127 | SH | SOLE | 0 | 1,335,956 | 0 | 43,171 | |
| Ecolab | COM | 278865100 | 5,637 | 31,931 | SH | DFND | 2 | 19,703 | 0 | 12,228 | |
| Ecolab | COM | 278865100 | 2,973 | 16,840 | SH | DFND | 1 | 16,840 | 0 | 0 | |
| Ecolab | COM | 278865100 | 734 | 4,158 | SH | DFND | 3 | 4,158 | 0 | 0 | |
| Edwards Lifesciences Corp | COM | 28176E108 | 254 | 1,327 | SH | DFND | 3 | 1,327 | 0 | 0 | |
| Estee Lauder 'A' | COM | 518439104 | 31,166 | 188,260 | SH | DFND | 2 | 188,260 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 15,934 | 831,215 | SH | DFND | 1 | 831,215 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 8,970 | 467,917 | SH | DFND | 2 | 22,986 | 0 | 444,931 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 73 | 3,812 | SH | DFND | 3 | 3,812 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 3,817 | 199,097 | SH | SOLE | 0 | 199,097 | 0 | 0 | |
| Eversource Energy | COM | 30040W108 | 27,884 | 393,005 | SH | DFND | 1 | 393,005 | 0 | 0 | |
| Eversource Energy | COM | 30040W108 | 1,645 | 23,183 | SH | DFND | 3 | 23,183 | 0 | 0 | |
| Eversource Energy | COM | 30040W108 | 34 | 480 | SH | DFND | 2 | 480 | 0 | 0 | |
| Evolent Health Inc A | CL A | 30050B101 | 4,526 | 359,780 | SH | DFND | 1 | 359,780 | 0 | 0 | |
| Evolent Health Inc A | CL A | 30050B101 | 4,216 | 335,149 | SH | DFND | 2 | 108,242 | 0 | 226,907 | |
| Evolent Health Inc A | CL A | 30050B101 | 1,072 | 85,239 | SH | DFND | 3 | 85,239 | 0 | 0 | |
| Evolent Health Inc A | CL A | 30050B101 | 3,689 | 293,216 | SH | SOLE | 0 | 293,216 | 0 | 0 | |
| Exact Sciences | COM | 30063P105 | 29,046 | 335,322 | SH | DFND | 1 | 335,322 | 0 | 0 | |
| Exact Sciences | COM | 30063P105 | 22,578 | 260,659 | SH | DFND | 2 | 85,365 | 0 | 175,294 | |
| Exact Sciences | COM | 30063P105 | 20,960 | 241,972 | SH | SOLE | 0 | 241,972 | 0 | 0 | |
| Exact Sciences | COM | 30063P105 | 6,655 | 76,826 | SH | DFND | 3 | 76,826 | 0 | 0 | |
| Exelon Corporation | COM | 30161N101 | 26,285 | 524,340 | SH | DFND | 1 | 524,340 | 0 | 0 | |
| Exelon Corporation | COM | 30161N101 | 36 | 710 | SH | DFND | 2 | 710 | 0 | 0 | |
| Exelon Corporation | COM | 30161N101 | 1,138 | 22,706 | SH | DFND | 3 | 22,706 | 0 | 0 | |
| Facebook Cl.A | CL A | 30303M102 | 395,194 | 2,370,834 | SH | DFND | 1 | 2,370,834 | 0 | 0 | |
| Facebook Cl.A | CL A | 30303M102 | 1,392,304 | 8,352,652 | SH | DFND | 2 | 3,609,808 | 0 | 4,742,844 | |
| Facebook Cl.A | CL A | 30303M102 | 110,361 | 662,073 | SH | DFND | 3 | 380,796 | 0 | 281,277 | |
| Facebook Cl.A | CL A | 30303M102 | 735,033 | 4,409,582 | SH | SOLE | 0 | 3,282,546 | 0 | 1,127,036 | |
| Faro Technologies | COM | 311642102 | 4,179 | 95,179 | SH | DFND | 1 | 95,179 | 0 | 0 | |
| Faro Technologies | COM | 311642102 | 6,492 | 147,854 | SH | DFND | 2 | 47,423 | 0 | 100,431 | |
| Faro Technologies | COM | 311642102 | 4,737 | 107,880 | SH | SOLE | 0 | 107,880 | 0 | 0 | |
| Faro Technologies | COM | 311642102 | 1,685 | 38,373 | SH | DFND | 3 | 38,373 | 0 | 0 | |
| Fastenal | COM | 311900104 | 27,092 | 421,274 | SH | DFND | 1 | 421,274 | 0 | 0 | |
| Fastenal | COM | 311900104 | 705 | 10,959 | SH | DFND | 3 | 10,959 | 0 | 0 | |
| Fastenal | COM | 311900104 | 15,103 | 234,848 | SH | DFND | 2 | 205,937 | 0 | 28,911 | |
| Fastenal | COM | 311900104 | 27,062 | 420,812 | SH | SOLE | 0 | 420,812 | 0 | 0 | |
| Ferrari NV | COM | N3167Y103 | 1,573,642 | 11,727,790 | SH | DFND | 2 | 3,623,231 | 0 | 8,104,559 | |
| Ferrari NV | COM | N3167Y103 | 322,033 | 2,400,000 | SH | SOLE | 0 | 2,400,000 | 0 | 0 | |
| Fiat Chrysler Automobiles | SHS | N31738102 | 20,649 | 1,385,644 | SH | DFND | 3 | 962,041 | 0 | 423,603 | |
| Fiat Chrysler Automobiles | SHS | N31738102 | 62,863 | 4,218,252 | SH | SOLE | 0 | 4,092,184 | 0 | 126,068 | |
| Fiat Chrysler Automobiles | SHS | N31738102 | 649,808 | 43,604,073 | SH | DFND | 2 | 16,573,365 | 0 | 27,030,708 | |
| Fiat Chrysler Automobiles | SHS | N31738102 | 29,087 | 1,951,829 | SH | DFND | 1 | 1,951,829 | 0 | 0 | |
| First Republic Bank | COM | 33616C100 | 183,569 | 1,827,285 | SH | DFND | 1 | 1,827,285 | 0 | 0 | |
| First Republic Bank | COM | 33616C100 | 167,652 | 1,668,844 | SH | SOLE | 0 | 1,633,168 | 0 | 35,676 | |
| First Republic Bank | COM | 33616C100 | 278,625 | 2,773,487 | SH | DFND | 2 | 1,749,393 | 0 | 1,024,094 | |
| First Republic Bank | COM | 33616C100 | 41,348 | 411,591 | SH | DFND | 3 | 287,943 | 0 | 123,648 | |
| Foamix Pharmaceuticals | SHS | M46135105 | 417 | 111,200 | SH | SOLE | 0 | 111,200 | 0 | 0 | |
| Foamix Pharmaceuticals | SHS | M46135105 | 406 | 108,200 | SH | DFND | 1 | 108,200 | 0 | 0 | |
| Fortive Corp | COM | 34959J108 | 23,620 | 281,559 | SH | SOLE | 0 | 281,559 | 0 | 0 | |
| Fortive Corp | COM | 34959J108 | 44,905 | 535,282 | SH | DFND | 2 | 181,946 | 0 | 353,336 | |
| Fortive Corp | COM | 34959J108 | 62,096 | 740,209 | SH | DFND | 1 | 740,209 | 0 | 0 | |
| Fortive Corp | COM | 34959J108 | 931 | 11,100 | SH | DFND | 3 | 11,100 | 0 | 0 | |
| Glaukos Corp | COM | 377322102 | 70,474 | 899,250 | SH | DFND | 1 | 899,250 | 0 | 0 | |
| Glaukos Corp | COM | 377322102 | 43,437 | 554,254 | SH | DFND | 2 | 78,676 | 0 | 475,578 | |
| Glaukos Corp | COM | 377322102 | 1,342 | 17,126 | SH | DFND | 3 | 17,126 | 0 | 0 | |
| Glaukos Corp | COM | 377322102 | 22,648 | 288,992 | SH | SOLE | 0 | 288,992 | 0 | 0 | |
| GrubHub Inc | COM | 400110102 | 189,133 | 2,722,519 | SH | DFND | 1 | 2,722,519 | 0 | 0 | |
| GrubHub Inc | COM | 400110102 | 231,898 | 3,338,102 | SH | DFND | 2 | 1,673,382 | 0 | 1,664,720 | |
| GrubHub Inc | COM | 400110102 | 178,262 | 2,566,035 | SH | SOLE | 0 | 2,526,558 | 0 | 39,477 | |
| GrubHub Inc | COM | 400110102 | 38,110 | 548,582 | SH | DFND | 3 | 410,886 | 0 | 137,696 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 10,299 | 403,569 | SH | DFND | 2 | 71,617 | 0 | 331,952 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 2,323 | 91,041 | SH | DFND | 1 | 91,041 | 0 | 0 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 12,682 | 496,931 | SH | DFND | 3 | 14,007 | 0 | 482,924 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 49,555 | 427,531 | SH | DFND | 2 | 326,019 | 0 | 101,512 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 84,532 | 729,290 | SH | SOLE | 0 | 729,290 | 0 | 0 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 16,431 | 141,757 | SH | DFND | 3 | 95,911 | 0 | 45,846 | |
| HEICO | COM | 422806109 | 14,676 | 154,699 | SH | DFND | 1 | 154,699 | 0 | 0 | |
| HEICO | COM | 422806109 | 8,474 | 89,322 | SH | SOLE | 0 | 89,322 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 32,746 | 389,550 | SH | DFND | 1 | 389,550 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 46,612 | 554,510 | SH | DFND | 2 | 274,235 | 0 | 280,275 | |
| HEICO 'A' | CL A | 422806208 | 194 | 2,304 | SH | DFND | 3 | 2,304 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 6,367 | 75,740 | SH | SOLE | 0 | 75,740 | 0 | 0 | |
| Himax Technologies Adr | SPONSORED ADR | 43289P106 | 2,156 | 675,800 | SH | DFND | 3 | 0 | 0 | 675,800 | |
| Howard Hughes | COM | 44267D107 | 26,909 | 244,623 | SH | DFND | 1 | 244,623 | 0 | 0 | |
| Howard Hughes | COM | 44267D107 | 57,969 | 526,990 | SH | SOLE | 0 | 510,362 | 0 | 16,628 | |
| Howard Hughes | COM | 44267D107 | 85,543 | 777,666 | SH | DFND | 2 | 587,037 | 0 | 190,629 | |
| Howard Hughes | COM | 44267D107 | 18,818 | 171,072 | SH | DFND | 3 | 116,838 | 0 | 54,234 | |
| Hutchison China Meditech | SPONSORED ADR | 44842L103 | 910 | 29,750 | SH | DFND | 1 | 29,750 | 0 | 0 | |
| Hutchison China Meditech | SPONSORED ADR | 44842L103 | 5,845 | 191,146 | SH | DFND | 3 | 0 | 0 | 191,146 | |
| ICICI Bank ADR | ADR | 45104G104 | 85,260 | 7,439,800 | SH | DFND | 3 | 5,654,652 | 0 | 1,785,148 | |
| ICICI Bank ADR | ADR | 45104G104 | 190,838 | 16,652,567 | SH | DFND | 2 | 12,523,412 | 0 | 4,129,155 | |
| ICICI Bank ADR | ADR | 45104G104 | 177,180 | 15,460,750 | SH | DFND | 1 | 15,460,750 | 0 | 0 | |
| ICICI Bank ADR | ADR | 45104G104 | 257,215 | 22,444,603 | SH | SOLE | 0 | 22,444,603 | 0 | 0 | |
| IPG Photonics Corp | COM | 44980X109 | 3,822 | 25,183 | SH | DFND | 3 | 25,183 | 0 | 0 | |
| IPG Photonics Corp | COM | 44980X109 | 14,816 | 97,617 | SH | DFND | 2 | 31,506 | 0 | 66,111 | |
| IPG Photonics Corp | COM | 44980X109 | 12,134 | 79,947 | SH | DFND | 1 | 79,947 | 0 | 0 | |
| IPG Photonics Corp | COM | 44980X109 | 11,176 | 73,636 | SH | SOLE | 0 | 73,636 | 0 | 0 | |
| Illumina | COM | 452327109 | 459,204 | 1,478,013 | SH | DFND | 1 | 1,478,013 | 0 | 0 | |
| Illumina | COM | 452327109 | 2,946,341 | 9,483,218 | SH | DFND | 2 | 2,438,795 | 0 | 7,044,423 | |
| Illumina | COM | 452327109 | 86,068 | 277,023 | SH | DFND | 3 | 124,295 | 0 | 152,728 | |
| Illumina | COM | 452327109 | 1,471,750 | 4,737,037 | SH | SOLE | 0 | 3,754,889 | 0 | 982,148 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 8,221 | 752,180 | SH | DFND | 1 | 752,180 | 0 | 0 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 2,758 | 252,366 | SH | DFND | 2 | 236,023 | 0 | 16,343 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 2,528 | 231,326 | SH | DFND | 3 | 108,909 | 0 | 122,417 | |
| Interactive Brokers Group | COM | 45841N107 | 91,429 | 1,760,627 | SH | DFND | 1 | 1,760,627 | 0 | 0 | |
| Interactive Brokers Group | COM | 45841N107 | 150,517 | 2,898,457 | SH | DFND | 2 | 1,903,572 | 0 | 994,885 | |
| Interactive Brokers Group | COM | 45841N107 | 91,608 | 1,764,069 | SH | SOLE | 0 | 1,723,483 | 0 | 40,586 | |
| Interactive Brokers Group | COM | 45841N107 | 23,880 | 459,858 | SH | DFND | 3 | 322,352 | 0 | 137,506 | |
| Intuitive Surgical | COM NEW | 46120E602 | 113,164 | 198,332 | SH | DFND | 1 | 198,332 | 0 | 0 | |
| Intuitive Surgical | COM NEW | 46120E602 | 694,977 | 1,218,019 | SH | DFND | 2 | 430,957 | 0 | 787,062 | |
| Intuitive Surgical | COM NEW | 46120E602 | 33,859 | 59,341 | SH | DFND | 3 | 24,958 | 0 | 34,383 | |
| Intuitive Surgical | COM NEW | 46120E602 | 389,738 | 683,055 | SH | SOLE | 0 | 462,918 | 0 | 220,137 | |
| Invesco Senior Income Trust | COM | 46131H107 | 12,592 | 2,998,119 | SH | DFND | 1 | 2,998,119 | 0 | 0 | |
| Invesco Senior Income Trust | COM | 46131H107 | 1,313 | 312,581 | SH | DFND | 3 | 312,581 | 0 | 0 | |
| Ionis Pharmaceuticals | COM | 462222100 | 72,890 | 897,989 | SH | DFND | 1 | 897,989 | 0 | 0 | |
| Ionis Pharmaceuticals | COM | 462222100 | 160,485 | 1,977,142 | SH | SOLE | 0 | 986,735 | 0 | 990,407 | |
| Ionis Pharmaceuticals | COM | 462222100 | 22,071 | 271,911 | SH | DFND | 3 | 115,905 | 0 | 156,006 | |
| Ionis Pharmaceuticals | COM | 462222100 | 446,217 | 5,497,309 | SH | DFND | 2 | 1,949,999 | 0 | 3,547,310 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 257,481 | 29,225,958 | SH | DFND | 2 | 12,710,935 | 0 | 16,515,023 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 86,173 | 9,781,230 | SH | DFND | 3 | 274,844 | 0 | 9,506,386 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 18,116 | 2,056,302 | SH | DFND | 1 | 2,056,302 | 0 | 0 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 18,488 | 2,098,498 | SH | SOLE | 0 | 2,098,498 | 0 | 0 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 183,333 | 6,080,680 | SH | DFND | 2 | 4,189,728 | 0 | 1,890,952 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 32,462 | 1,076,692 | SH | DFND | 1 | 1,076,692 | 0 | 0 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 52,749 | 1,749,553 | SH | DFND | 3 | 69,112 | 0 | 1,680,441 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 10,304 | 341,766 | SH | SOLE | 0 | 341,766 | 0 | 0 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 116,931 | 6,223,054 | SH | DFND | 2 | 4,694,665 | 0 | 1,528,389 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 36,812 | 1,959,101 | SH | DFND | 1 | 1,959,101 | 0 | 0 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 26,460 | 1,408,202 | SH | DFND | 3 | 972,307 | 0 | 435,895 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 79,024 | 4,205,648 | SH | SOLE | 0 | 4,075,906 | 0 | 129,742 | |
| Jianpu Technology Inc- ADR | ADR | 47738D101 | 11,963 | 2,387,902 | SH | DFND | 1 | 2,387,902 | 0 | 0 | |
| Jianpu Technology Inc- ADR | ADR | 47738D101 | 7,435 | 1,484,017 | SH | SOLE | 0 | 1,484,017 | 0 | 0 | |
| Johnson & Johnson | COM | 478160104 | 6,769 | 48,421 | SH | DFND | 1 | 48,421 | 0 | 0 | |
| Johnson & Johnson | COM | 478160104 | 588 | 4,203 | SH | DFND | 2 | 0 | 0 | 4,203 | |
| Johnson & Johnson | COM | 478160104 | 7,062 | 50,522 | SH | SOLE | 0 | 50,522 | 0 | 0 | |
| Kaleido Biosciences Inc | COM | 483347100 | 3,574 | 246,500 | SH | DFND | 1 | 246,500 | 0 | 0 | |
| Kaleido Biosciences Inc | COM | 483347100 | 2,806 | 193,500 | SH | SOLE | 0 | 193,500 | 0 | 0 | |
| Kirby | COM | 497266106 | 82,184 | 1,094,186 | SH | DFND | 1 | 1,094,186 | 0 | 0 | |
| Kirby | COM | 497266106 | 264,711 | 3,524,309 | SH | DFND | 2 | 2,675,449 | 0 | 848,860 | |
| Kirby | COM | 497266106 | 174,012 | 2,316,760 | SH | SOLE | 0 | 2,243,136 | 0 | 73,624 | |
| Kirby | COM | 497266106 | 58,360 | 776,998 | SH | DFND | 3 | 533,523 | 0 | 243,475 | |
| Korea Electric Power ADR | SPONSORED ADR | 500631106 | 22 | 1,700 | SH | DFND | 2 | 1,700 | 0 | 0 | |
| Korea Electric Power ADR | SPONSORED ADR | 500631106 | 954 | 73,300 | SH | DFND | 3 | 73,300 | 0 | 0 | |
| LIBERTY MEDIA CORP | DEB 4.00011/1 | 530715AG6 | 13,657 | 20,955,000 | SH | DFND | 1 | 20,955,000 | 0 | 0 | |
| LIBERTY MEDIA CORP | DEB 4.00011/1 | 530715AG6 | 6 | 9,000 | SH | DFND | 2 | 9,000 | 0 | 0 | |
| LIBERTY MEDIA CORP | DEB 4.00011/1 | 530715AG6 | 1,112 | 1,706,000 | SH | DFND | 3 | 1,706,000 | 0 | 0 | |
| LendingTree | COM | 52603B107 | 95,075 | 270,437 | SH | DFND | 1 | 270,437 | 0 | 0 | |
| LendingTree | COM | 52603B107 | 203,416 | 578,611 | SH | DFND | 2 | 356,183 | 0 | 222,428 | |
| LendingTree | COM | 52603B107 | 47,728 | 135,760 | SH | DFND | 3 | 109,559 | 0 | 26,201 | |
| LendingTree | COM | 52603B107 | 139,431 | 396,606 | SH | SOLE | 0 | 388,597 | 0 | 8,009 | |
| Lincoln Electric Hdg. | COM | 533900106 | 4,295 | 51,216 | SH | DFND | 2 | 51,216 | 0 | 0 | |
| Lindblad Expeditions Holdings | COM | 535219109 | 16,359 | 1,072,701 | SH | SOLE | 0 | 1,072,701 | 0 | 0 | |
| Line Corp Sponsored Adr | SPONSORED ADR | 53567X101 | 10,830 | 307,597 | SH | DFND | 2 | 10,721 | 0 | 296,876 | |
| Luxoft Holding | ORD SHS CL A | G57279104 | 5,691 | 96,930 | SH | DFND | 3 | 0 | 0 | 96,930 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 30,538 | 390,057 | SH | DFND | 1 | 390,057 | 0 | 0 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 16,018 | 204,597 | SH | DFND | 2 | 11,904 | 0 | 192,693 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 445 | 5,678 | SH | DFND | 3 | 5,678 | 0 | 0 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 31,290 | 399,668 | SH | SOLE | 0 | 399,668 | 0 | 0 | |
| M&T Bank | COM | 55261F104 | 15,194 | 96,766 | SH | DFND | 2 | 96,766 | 0 | 0 | |
| MRC Global | COM | 55345K103 | 11,362 | 650,000 | SH | SOLE | 0 | 650,000 | 0 | 0 | |
| MakeMyTrip | SHS | V5633W109 | 89,988 | 3,260,419 | SH | DFND | 2 | 2,063,649 | 0 | 1,196,770 | |
| Markel Corp | COM | 570535104 | 101,417 | 101,800 | SH | DFND | 1 | 101,800 | 0 | 0 | |
| Markel Corp | COM | 570535104 | 249,845 | 250,788 | SH | DFND | 2 | 182,198 | 0 | 68,590 | |
| Markel Corp | COM | 570535104 | 46,302 | 46,477 | SH | DFND | 3 | 32,037 | 0 | 14,440 | |
| Markel Corp | COM | 570535104 | 152,210 | 152,784 | SH | SOLE | 0 | 148,662 | 0 | 4,122 | |
| MarketAxess Holdings | COM | 57060D108 | 60,103 | 244,240 | SH | DFND | 3 | 183,740 | 0 | 60,500 | |
| MarketAxess Holdings | COM | 57060D108 | 391,031 | 1,589,041 | SH | DFND | 2 | 878,354 | 0 | 710,687 | |
| MarketAxess Holdings | COM | 57060D108 | 297,400 | 1,208,551 | SH | DFND | 1 | 1,208,551 | 0 | 0 | |
| MarketAxess Holdings | COM | 57060D108 | 244,816 | 994,863 | SH | SOLE | 0 | 976,786 | 0 | 18,077 | |
| Martin Marietta Materials | COM | 573284106 | 81,985 | 407,521 | SH | DFND | 1 | 407,521 | 0 | 0 | |
| Martin Marietta Materials | COM | 573284106 | 266,071 | 1,322,554 | SH | DFND | 2 | 1,015,841 | 0 | 306,713 | |
| Martin Marietta Materials | COM | 573284106 | 57,050 | 283,578 | SH | DFND | 3 | 196,328 | 0 | 87,250 | |
| Martin Marietta Materials | COM | 573284106 | 173,142 | 860,632 | SH | SOLE | 0 | 833,469 | 0 | 27,163 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 298,411 | 1,267,408 | SH | DFND | 1 | 1,267,408 | 0 | 0 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 604,648 | 2,568,051 | SH | DFND | 2 | 1,750,641 | 0 | 817,410 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 371,760 | 1,578,936 | SH | SOLE | 0 | 1,535,838 | 0 | 43,098 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 108,130 | 459,247 | SH | DFND | 3 | 319,206 | 0 | 140,041 | |
| McDonald's | COM | 580135101 | 1,448 | 7,624 | SH | DFND | 2 | 0 | 0 | 7,624 | |
| McDonald's | COM | 580135101 | 17,162 | 90,372 | SH | DFND | 1 | 90,372 | 0 | 0 | |
| McDonald's | COM | 580135101 | 17,567 | 92,507 | SH | SOLE | 0 | 92,507 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 88,937 | 175,166 | SH | DFND | 1 | 175,166 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 2,148,714 | 4,232,002 | SH | DFND | 2 | 1,566,132 | 0 | 2,665,870 | |
| MercadoLibre | COM | 58733R102 | 110,971 | 218,564 | SH | SOLE | 0 | 218,564 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 127,357 | 250,836 | SH | DFND | 3 | 18,036 | 0 | 232,800 | |
| Mettler-Toledo | COM | 592688105 | 70,225 | 97,130 | SH | DFND | 1 | 97,130 | 0 | 0 | |
| Mettler-Toledo | COM | 592688105 | 347,903 | 481,193 | SH | DFND | 2 | 319,401 | 0 | 161,792 | |
| Mettler-Toledo | COM | 592688105 | 2,876 | 3,978 | SH | DFND | 3 | 3,978 | 0 | 0 | |
| Mettler-Toledo | COM | 592688105 | 36,757 | 50,840 | SH | SOLE | 0 | 50,840 | 0 | 0 | |
| Microsoft | COM | 594918104 | 105,666 | 895,932 | SH | DFND | 1 | 895,932 | 0 | 0 | |
| Microsoft | COM | 594918104 | 320,660 | 2,718,843 | SH | DFND | 2 | 2,141,334 | 0 | 577,509 | |
| Microsoft | COM | 594918104 | 60,015 | 508,863 | SH | DFND | 3 | 349,504 | 0 | 159,359 | |
| Microsoft | COM | 594918104 | 201,010 | 1,704,342 | SH | SOLE | 0 | 1,657,362 | 0 | 46,980 | |
| Mobile Telesystems ADR | SPONSORED ADR | 607409109 | 160 | 21,100 | SH | DFND | 1 | 21,100 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 26,785 | 1,316,234 | SH | DFND | 1 | 1,316,234 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 16,308 | 801,379 | SH | DFND | 2 | 112,746 | 0 | 688,633 | |
| Moderna Inc | COM | 60770K107 | 8,758 | 430,344 | SH | SOLE | 0 | 430,344 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 554 | 27,244 | SH | DFND | 3 | 27,244 | 0 | 0 | |
| Moody's Corp | COM | 615369105 | 153,374 | 846,948 | SH | DFND | 1 | 846,948 | 0 | 0 | |
| Moody's Corp | COM | 615369105 | 506,190 | 2,795,242 | SH | DFND | 2 | 2,133,030 | 0 | 662,212 | |
| Moody's Corp | COM | 615369105 | 108,651 | 599,986 | SH | DFND | 3 | 415,301 | 0 | 184,685 | |
| Moody's Corp | COM | 615369105 | 320,554 | 1,770,136 | SH | SOLE | 0 | 1,714,739 | 0 | 55,397 | |
| Myriad Genetics Inc | COM | 62855J104 | 46,262 | 1,393,446 | SH | DFND | 1 | 1,393,446 | 0 | 0 | |
| Myriad Genetics Inc | COM | 62855J104 | 143,651 | 4,326,831 | SH | DFND | 2 | 3,269,138 | 0 | 1,057,693 | |
| Myriad Genetics Inc | COM | 62855J104 | 32,122 | 967,526 | SH | DFND | 3 | 660,987 | 0 | 306,539 | |
| Myriad Genetics Inc | COM | 62855J104 | 94,712 | 2,852,783 | SH | SOLE | 0 | 2,761,141 | 0 | 91,642 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 7,566 | 1,483,478 | SH | DFND | 3 | 625,395 | 0 | 858,083 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 313,353 | 61,441,800 | SH | DFND | 2 | 18,761,899 | 0 | 42,679,901 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 25,635 | 5,026,397 | SH | DFND | 1 | 5,026,397 | 0 | 0 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 172,560 | 33,835,374 | SH | SOLE | 0 | 28,426,390 | 0 | 5,408,984 | |
| NVIDIA | COM | 67066G104 | 34,504 | 192,161 | SH | DFND | 3 | 85,350 | 0 | 106,811 | |
| NVIDIA | COM | 67066G104 | 760,411 | 4,234,858 | SH | DFND | 2 | 1,578,229 | 0 | 2,656,629 | |
| NVIDIA | COM | 67066G104 | 154,038 | 857,864 | SH | DFND | 1 | 857,864 | 0 | 0 | |
| NVIDIA | COM | 67066G104 | 424,203 | 2,362,459 | SH | SOLE | 0 | 1,657,045 | 0 | 705,414 | |
| National Instruments Corp | COM | 636518102 | 13,911 | 313,596 | SH | DFND | 1 | 313,596 | 0 | 0 | |
| National Instruments Corp | COM | 636518102 | 6,832 | 154,006 | SH | DFND | 2 | 43,711 | 0 | 110,295 | |
| National Instruments Corp | COM | 636518102 | 1,568 | 35,355 | SH | DFND | 3 | 35,355 | 0 | 0 | |
| National Instruments Corp | COM | 636518102 | 14,653 | 330,310 | SH | SOLE | 0 | 330,310 | 0 | 0 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 56,470 | 233,877 | SH | DFND | 1 | 233,877 | 0 | 0 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 318,193 | 1,317,843 | SH | DFND | 2 | 464,650 | 0 | 853,193 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 16,120 | 66,762 | SH | DFND | 3 | 28,041 | 0 | 38,721 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 117,982 | 488,640 | SH | SOLE | 0 | 245,034 | 0 | 243,606 | |
| Netflix Inc | COM | 64110L106 | 432,265 | 1,212,321 | SH | DFND | 1 | 1,212,321 | 0 | 0 | |
| Netflix Inc | COM | 64110L106 | 1,312,295 | 3,680,432 | SH | DFND | 2 | 1,469,003 | 0 | 2,211,429 | |
| Netflix Inc | COM | 64110L106 | 873,124 | 2,448,744 | SH | SOLE | 0 | 1,937,846 | 0 | 510,898 | |
| Netflix Inc | COM | 64110L106 | 85,116 | 238,713 | SH | DFND | 3 | 129,897 | 0 | 108,816 | |
| New Relic | COM | 64829B100 | 229 | 2,325 | SH | DFND | 3 | 2,325 | 0 | 0 | |
| New Relic | COM | 64829B100 | 29,147 | 295,312 | SH | DFND | 2 | 15,992 | 0 | 279,320 | |
| New Relic | COM | 64829B100 | 52,956 | 536,537 | SH | DFND | 1 | 536,537 | 0 | 0 | |
| New Relic | COM | 64829B100 | 18,160 | 183,987 | SH | SOLE | 0 | 183,987 | 0 | 0 | |
| Novocure Ltd | ORD SHS | G6674U108 | 22,504 | 467,176 | SH | DFND | 3 | 361,356 | 0 | 105,820 | |
| Novocure Ltd | ORD SHS | G6674U108 | 139,519 | 2,896,398 | SH | DFND | 2 | 1,350,557 | 0 | 1,545,841 | |
| Novocure Ltd | ORD SHS | G6674U108 | 125,653 | 2,608,542 | SH | DFND | 1 | 2,608,542 | 0 | 0 | |
| Novocure Ltd | ORD SHS | G6674U108 | 99,587 | 2,067,409 | SH | SOLE | 0 | 2,035,850 | 0 | 31,559 | |
| Now Inc/DE | COM | 67011P100 | 51,394 | 3,681,512 | SH | DFND | 1 | 3,681,512 | 0 | 0 | |
| Now Inc/DE | COM | 67011P100 | 88,507 | 6,340,022 | SH | DFND | 2 | 4,058,285 | 0 | 2,281,737 | |
| Now Inc/DE | COM | 67011P100 | 13,985 | 1,001,765 | SH | DFND | 3 | 706,779 | 0 | 294,986 | |
| Now Inc/DE | COM | 67011P100 | 61,835 | 4,429,470 | SH | SOLE | 0 | 4,331,974 | 0 | 97,496 | |
| Nucana Plc ADR | SPONSORED ADR | 67022C106 | 5,714 | 336,100 | SH | SOLE | 0 | 336,100 | 0 | 0 | |
| Nucana Plc ADR | SPONSORED ADR | 67022C106 | 8,351 | 491,208 | SH | DFND | 1 | 491,208 | 0 | 0 | |
| Nuveen Senior Income Fund | COM | 67067Y104 | 2,225 | 383,602 | SH | DFND | 1 | 383,602 | 0 | 0 | |
| Orchard Therapeutics PLC ADR | ADS | 68570P101 | 16,539 | 925,000 | SH | SOLE | 0 | 925,000 | 0 | 0 | |
| Pacira Pharmaceuticals | COM | 695127100 | 13,489 | 354,403 | SH | DFND | 1 | 354,403 | 0 | 0 | |
| Pacira Pharmaceuticals | COM | 695127100 | 11,370 | 298,744 | SH | DFND | 2 | 97,470 | 0 | 201,274 | |
| Pacira Pharmaceuticals | COM | 695127100 | 3,214 | 84,435 | SH | DFND | 3 | 84,435 | 0 | 0 | |
| Pacira Pharmaceuticals | COM | 695127100 | 9,642 | 253,326 | SH | SOLE | 0 | 253,326 | 0 | 0 | |
| Penumbra Inc | COM | 70975L107 | 67,275 | 457,624 | SH | DFND | 1 | 457,624 | 0 | 0 | |
| Penumbra Inc | COM | 70975L107 | 40,087 | 272,682 | SH | DFND | 2 | 30,126 | 0 | 242,556 | |
| Penumbra Inc | COM | 70975L107 | 25,995 | 176,828 | SH | SOLE | 0 | 176,828 | 0 | 0 | |
| Penumbra Inc | COM | 70975L107 | 2,612 | 17,770 | SH | DFND | 3 | 17,770 | 0 | 0 | |
| Pepsico | COM | 713448108 | 1,393 | 11,367 | SH | DFND | 2 | 0 | 0 | 11,367 | |
| Pepsico | COM | 713448108 | 16,420 | 133,988 | SH | DFND | 1 | 133,988 | 0 | 0 | |
| Pepsico | COM | 713448108 | 16,589 | 135,366 | SH | SOLE | 0 | 135,366 | 0 | 0 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 60,433 | 3,796,060 | SH | DFND | 1 | 3,796,060 | 0 | 0 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 13,752 | 863,825 | SH | SOLE | 0 | 863,825 | 0 | 0 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 373,309 | 23,449,053 | SH | DFND | 2 | 5,487,690 | 0 | 17,961,363 | |
| Petrobras Pref ADR | SP ADR NON VTG | 71654V101 | 7,716 | 539,592 | SH | DFND | 1 | 539,592 | 0 | 0 | |
| Petrobras Pref ADR | SP ADR NON VTG | 71654V101 | 58,681 | 4,103,538 | SH | DFND | 2 | 1,280,425 | 0 | 2,823,113 | |
| Pinduoduo Inc ADR | SPONSORED ADS | 722304102 | 964 | 38,867 | SH | DFND | 1 | 38,867 | 0 | 0 | |
| Pinduoduo Inc ADR | SPONSORED ADS | 722304102 | 51,766 | 2,087,330 | SH | SOLE | 0 | 2,087,330 | 0 | 0 | |
| Pioneer Floating Rate Trust | COM | 72369J102 | 5,730 | 550,936 | SH | DFND | 1 | 550,936 | 0 | 0 | |
| PriceSmart | COM | 741511109 | 61,868 | 1,050,745 | SH | DFND | 2 | 777,674 | 0 | 273,071 | |
| PriceSmart | COM | 741511109 | 8,727 | 148,222 | SH | SOLE | 0 | 148,222 | 0 | 0 | |
| Procter & Gamble | COM | 742718109 | 1,889 | 18,158 | SH | DFND | 2 | 0 | 0 | 18,158 | |
| Procter & Gamble | COM | 742718109 | 23,162 | 222,606 | SH | DFND | 1 | 222,606 | 0 | 0 | |
| Procter & Gamble | COM | 742718109 | 23,322 | 224,145 | SH | SOLE | 0 | 224,145 | 0 | 0 | |
| Redfin | COM | 75737F108 | 763 | 37,637 | SH | DFND | 3 | 37,637 | 0 | 0 | |
| Redfin | COM | 75737F108 | 25,807 | 1,273,163 | SH | DFND | 2 | 73,888 | 0 | 1,199,275 | |
| Redfin | COM | 75737F108 | 50,357 | 2,484,333 | SH | DFND | 1 | 2,484,333 | 0 | 0 | |
| Redfin | COM | 75737F108 | 19,302 | 952,249 | SH | SOLE | 0 | 952,249 | 0 | 0 | |
| ResMed | COM | 761152107 | 50,352 | 484,298 | SH | DFND | 3 | 334,044 | 0 | 150,254 | |
| ResMed | COM | 761152107 | 227,486 | 2,188,001 | SH | DFND | 2 | 1,665,403 | 0 | 522,598 | |
| ResMed | COM | 761152107 | 70,173 | 674,936 | SH | DFND | 1 | 674,936 | 0 | 0 | |
| ResMed | COM | 761152107 | 150,813 | 1,450,546 | SH | SOLE | 0 | 1,405,592 | 0 | 44,954 | |
| ResTORbio Inc | COM | 76133L103 | 4,461 | 654,147 | SH | DFND | 1 | 654,147 | 0 | 0 | |
| ResTORbio Inc | COM | 76133L103 | 4,210 | 617,240 | SH | SOLE | 0 | 617,240 | 0 | 0 | |
| Rio Tinto Spn.Adr 1:1 | SPONSORED ADR | 767204100 | 4,156 | 70,626 | SH | DFND | 2 | 70,626 | 0 | 0 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 34,368 | 1,010,821 | SH | DFND | 1 | 1,010,821 | 0 | 0 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 176,782 | 5,199,467 | SH | DFND | 2 | 3,973,528 | 0 | 1,225,939 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 24,344 | 715,991 | SH | DFND | 3 | 490,331 | 0 | 225,660 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 72,156 | 2,122,233 | SH | SOLE | 0 | 2,054,341 | 0 | 67,892 | |
| Ritchie Bros. Auctioneers | COM | 767744105 | 49,955 | 1,470,958 | SH | DFND | 2 | 736,995 | 0 | 733,963 | |
| Ritchie Bros. Auctioneers | COM | 767744105 | 13,481 | 396,943 | SH | SOLE | 0 | 396,943 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 263 | 4,081 | SH | DFND | 3 | 4,081 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 35,220 | 545,959 | SH | DFND | 2 | 28,758 | 0 | 517,201 | |
| Roku | COM CL A | 77543R102 | 60,994 | 945,502 | SH | DFND | 1 | 945,502 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 21,474 | 332,882 | SH | SOLE | 0 | 332,882 | 0 | 0 | |
| Royal Crbn.Cruises | COM | V7780T103 | 53,693 | 468,447 | SH | DFND | 3 | 322,600 | 0 | 145,847 | |
| Royal Crbn.Cruises | COM | V7780T103 | 243,992 | 2,128,701 | SH | DFND | 2 | 1,607,605 | 0 | 521,096 | |
| Royal Crbn.Cruises | COM | V7780T103 | 75,219 | 656,249 | SH | DFND | 1 | 656,249 | 0 | 0 | |
| Royal Crbn.Cruises | COM | V7780T103 | 160,840 | 1,403,249 | SH | SOLE | 0 | 1,360,887 | 0 | 42,362 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 7,108 | 392,700 | SH | DFND | 1 | 392,700 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 2,873 | 158,748 | SH | DFND | 2 | 51,470 | 0 | 107,278 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 833 | 46,038 | SH | DFND | 3 | 46,038 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 63,990 | 3,535,365 | SH | SOLE | 0 | 3,535,365 | 0 | 0 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 485,606 | 6,479,929 | SH | DFND | 2 | 4,546,721 | 0 | 1,933,208 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 5,330 | 71,119 | SH | DFND | 3 | 8,377 | 0 | 62,742 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 3,965 | 52,904 | SH | SOLE | 0 | 52,904 | 0 | 0 | |
| SEA Ltd ADR | ADR | 81141R100 | 12,646 | 537,684 | SH | DFND | 1 | 537,684 | 0 | 0 | |
| SEA Ltd ADR | ADR | 81141R100 | 52,910 | 2,249,558 | SH | DFND | 2 | 0 | 0 | 2,249,558 | |
| SEA Ltd ADR | ADR | 81141R100 | 15,079 | 641,104 | SH | SOLE | 0 | 641,104 | 0 | 0 | |
| SINA Corp | ORD | G81477104 | 7,793 | 131,550 | SH | DFND | 3 | 0 | 0 | 131,550 | |
| SOLARCITY CORP | NOTE 1.625 11/0 | 83416TAC4 | 4,564 | 4,677,000 | SH | DFND | 3 | 4,677,000 | 0 | 0 | |
| SOLARCITY CORP | NOTE 1.625 11/0 | 83416TAC4 | 7 | 7,000 | SH | DFND | 2 | 7,000 | 0 | 0 | |
| SOLARCITY CORP | NOTE 1.625 11/0 | 83416TAC4 | 27,404 | 28,083,000 | SH | DFND | 1 | 28,083,000 | 0 | 0 | |
| SUNPOWER CORP | DBCV 4.000 1/1 | 867652AL3 | 3,277 | 3,918,000 | SH | DFND | 1 | 3,918,000 | 0 | 0 | |
| SUNPOWER CORP | DBCV 4.000 1/1 | 867652AL3 | 683 | 817,000 | SH | DFND | 3 | 817,000 | 0 | 0 | |
| SVMK INC | COM | 78489X103 | 32,227 | 1,769,756 | SH | SOLE | 0 | 1,769,756 | 0 | 0 | |
| Salesforce.com | COM | 79466L302 | 537,020 | 3,390,917 | SH | DFND | 2 | 1,197,790 | 0 | 2,193,127 | |
| Salesforce.com | COM | 79466L302 | 87,081 | 549,860 | SH | DFND | 1 | 549,860 | 0 | 0 | |
| Salesforce.com | COM | 79466L302 | 26,058 | 164,537 | SH | DFND | 3 | 69,098 | 0 | 95,439 | |
| Salesforce.com | COM | 79466L302 | 192,375 | 1,214,717 | SH | SOLE | 0 | 605,240 | 0 | 609,477 | |
| Schlumberger | COM | 806857108 | 4,816 | 110,529 | SH | DFND | 2 | 110,529 | 0 | 0 | |
| Seattle Genetics | COM | 812578102 | 150,109 | 2,049,547 | SH | SOLE | 0 | 1,992,301 | 0 | 57,246 | |
| Seattle Genetics | COM | 812578102 | 47,990 | 655,246 | SH | DFND | 3 | 455,042 | 0 | 200,204 | |
| Seattle Genetics | COM | 812578102 | 219,484 | 2,996,774 | SH | DFND | 2 | 2,238,737 | 0 | 758,037 | |
| Seattle Genetics | COM | 812578102 | 71,905 | 981,769 | SH | DFND | 1 | 981,769 | 0 | 0 | |
| Service Corp.Intl. | COM | 817565104 | 66,971 | 1,668,008 | SH | DFND | 1 | 1,668,008 | 0 | 0 | |
| Service Corp.Intl. | COM | 817565104 | 217,502 | 5,417,234 | SH | DFND | 2 | 4,111,371 | 0 | 1,305,863 | |
| Service Corp.Intl. | COM | 817565104 | 48,141 | 1,199,038 | SH | DFND | 3 | 825,957 | 0 | 373,081 | |
| Service Corp.Intl. | COM | 817565104 | 143,558 | 3,575,543 | SH | SOLE | 0 | 3,468,067 | 0 | 107,476 | |
| Severstal GDR Reg S | COM | 818150302 | 160 | 10,286 | SH | DFND | 1 | 10,286 | 0 | 0 | |
| Sherwin-Williams Co | COM | 824348106 | 8,435 | 19,584 | SH | DFND | 2 | 19,584 | 0 | 0 | |
| Ship Finance Intl | SHS | G81075106 | 158 | 12,800 | SH | DFND | 1 | 12,800 | 0 | 0 | |
| Shopify 'A' | CL A | 82509L107 | 48,516 | 234,809 | SH | DFND | 3 | 147,874 | 0 | 86,935 | |
| Shopify 'A' | CL A | 82509L107 | 293,028 | 1,418,197 | SH | SOLE | 0 | 1,176,051 | 0 | 242,146 | |
| Shopify 'A' | CL A | 82509L107 | 672,902 | 3,256,711 | SH | DFND | 2 | 1,756,362 | 0 | 1,500,349 | |
| Shopify 'A' | CL A | 82509L107 | 208,753 | 1,010,322 | SH | DFND | 1 | 1,010,322 | 0 | 0 | |
| SiteOne Landscape Supply | COM | 82982L103 | 45,852 | 802,314 | SH | SOLE | 0 | 777,704 | 0 | 24,610 | |
| SiteOne Landscape Supply | COM | 82982L103 | 20,948 | 366,552 | SH | DFND | 1 | 366,552 | 0 | 0 | |
| SiteOne Landscape Supply | COM | 82982L103 | 66,576 | 1,164,929 | SH | DFND | 2 | 895,490 | 0 | 269,439 | |
| SiteOne Landscape Supply | COM | 82982L103 | 14,752 | 258,121 | SH | DFND | 3 | 182,452 | 0 | 75,669 | |
| Snap Inc | CL A | 83304A106 | 1,756 | 159,389 | SH | DFND | 2 | 159,389 | 0 | 0 | |
| Sohu.com | COM | 83410S108 | 3,318 | 200,140 | SH | DFND | 3 | 0 | 0 | 200,140 | |
| Splunk Inc | COM | 848637104 | 9,206 | 73,884 | SH | SOLE | 0 | 73,884 | 0 | 0 | |
| Splunk Inc | COM | 848637104 | 4,066 | 32,631 | SH | DFND | 3 | 32,631 | 0 | 0 | |
| Splunk Inc | COM | 848637104 | 12,577 | 100,940 | SH | DFND | 1 | 100,940 | 0 | 0 | |
| Splunk Inc | COM | 848637104 | 15,790 | 126,723 | SH | DFND | 2 | 41,028 | 0 | 85,695 | |
| Spotify Technology SA | SHS | L8681T102 | 47,867 | 344,864 | SH | DFND | 3 | 196,210 | 0 | 148,654 | |
| Spotify Technology SA | SHS | L8681T102 | 1,856,582 | 13,375,948 | SH | DFND | 2 | 5,304,363 | 0 | 8,071,585 | |
| Spotify Technology SA | SHS | L8681T102 | 534,476 | 3,850,689 | SH | SOLE | 0 | 3,158,871 | 0 | 691,818 | |
| Spotify Technology SA | SHS | L8681T102 | 165,236 | 1,190,459 | SH | DFND | 1 | 1,190,459 | 0 | 0 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 4,758 | 139,172 | SH | DFND | 3 | 139,172 | 0 | 0 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 24,129 | 705,742 | SH | DFND | 1 | 705,742 | 0 | 0 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 15,294 | 447,337 | SH | SOLE | 0 | 447,337 | 0 | 0 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 16,478 | 481,950 | SH | DFND | 2 | 159,376 | 0 | 322,574 | |
| Stericycle Inc | COM | 858912108 | 133,990 | 2,462,143 | SH | DFND | 2 | 1,875,814 | 0 | 586,329 | |
| Stericycle Inc | COM | 858912108 | 41,384 | 760,447 | SH | DFND | 1 | 760,447 | 0 | 0 | |
| Stericycle Inc | COM | 858912108 | 29,466 | 541,451 | SH | DFND | 3 | 372,682 | 0 | 168,769 | |
| Stericycle Inc | COM | 858912108 | 87,515 | 1,608,142 | SH | SOLE | 0 | 1,557,378 | 0 | 50,764 | |
| Stitch Fix | COM CL A | 860897107 | 238 | 8,421 | SH | DFND | 3 | 8,421 | 0 | 0 | |
| Stitch Fix | COM CL A | 860897107 | 29,759 | 1,054,164 | SH | DFND | 2 | 56,733 | 0 | 997,431 | |
| Stitch Fix | COM CL A | 860897107 | 53,919 | 1,909,975 | SH | DFND | 1 | 1,909,975 | 0 | 0 | |
| Stitch Fix | COM CL A | 860897107 | 18,817 | 666,569 | SH | SOLE | 0 | 666,569 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 2,152 | 90,346 | SH | DFND | 3 | 90,346 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 3,444 | 144,600 | SH | SOLE | 0 | 144,600 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 5,390 | 226,300 | SH | DFND | 1 | 226,300 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 8,191 | 343,871 | SH | DFND | 2 | 110,243 | 0 | 233,628 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 72,197 | 2,001,018 | SH | DFND | 1 | 2,001,018 | 0 | 0 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 1,440,624 | 39,928,590 | SH | DFND | 2 | 10,051,623 | 0 | 29,876,967 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 21,650 | 600,042 | SH | DFND | 3 | 251,528 | 0 | 348,514 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 158,408 | 4,390,475 | SH | SOLE | 0 | 2,199,491 | 0 | 2,190,984 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 53,679 | 1,073,800 | SH | DFND | 1 | 1,073,800 | 0 | 0 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 184,117 | 3,683,075 | SH | DFND | 2 | 2,910,128 | 0 | 772,947 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 36,401 | 728,168 | SH | DFND | 3 | 504,338 | 0 | 223,830 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 110,078 | 2,201,992 | SH | SOLE | 0 | 2,134,449 | 0 | 67,543 | |
| TJX Companies | COM | 872540109 | 545 | 10,251 | SH | DFND | 3 | 10,251 | 0 | 0 | |
| TJX Companies | COM | 872540109 | 22,088 | 415,112 | SH | DFND | 2 | 401,563 | 0 | 13,549 | |
| TJX Companies | COM | 872540109 | 11,752 | 220,856 | SH | DFND | 1 | 220,856 | 0 | 0 | |
| TJX Companies | COM | 872540109 | 4,662 | 87,612 | SH | SOLE | 0 | 87,612 | 0 | 0 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 94,391 | 2,304,461 | SH | DFND | 1 | 2,304,461 | 0 | 0 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 762,068 | 18,605,182 | SH | DFND | 2 | 11,445,375 | 0 | 7,159,807 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 59,308 | 1,447,949 | SH | DFND | 3 | 1,018,352 | 0 | 429,597 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 183,155 | 4,471,567 | SH | SOLE | 0 | 4,337,583 | 0 | 133,984 | |
| Tableau Software Class A | CL A | 87336U105 | 91,125 | 715,941 | SH | DFND | 1 | 715,941 | 0 | 0 | |
| Tableau Software Class A | CL A | 87336U105 | 47,333 | 371,883 | SH | DFND | 2 | 21,932 | 0 | 349,951 | |
| Tableau Software Class A | CL A | 87336U105 | 124,054 | 974,658 | SH | SOLE | 0 | 974,658 | 0 | 0 | |
| Tableau Software Class A | CL A | 87336U105 | 1,572 | 12,354 | SH | DFND | 3 | 12,354 | 0 | 0 | |
| Tandem Diabetes Care | COM NEW | 875372203 | 13,310 | 209,600 | SH | SOLE | 0 | 209,600 | 0 | 0 | |
| Tandem Diabetes Care | COM NEW | 875372203 | 14,294 | 225,100 | SH | DFND | 1 | 225,100 | 0 | 0 | |
| Targa Resources | COM | 87612G101 | 108 | 2,599 | SH | DFND | 1 | 2,599 | 0 | 0 | |
| Teladoc | COM | 87918A105 | 4,657 | 83,755 | SH | DFND | 3 | 83,755 | 0 | 0 | |
| Teladoc | COM | 87918A105 | 17,279 | 310,780 | SH | DFND | 2 | 100,095 | 0 | 210,685 | |
| Teladoc | COM | 87918A105 | 17,774 | 319,681 | SH | DFND | 1 | 319,681 | 0 | 0 | |
| Teladoc | COM | 87918A105 | 9,627 | 173,152 | SH | SOLE | 0 | 173,152 | 0 | 0 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 150,888 | 8,336,352 | SH | DFND | 2 | 5,343,257 | 0 | 2,993,095 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 6,919 | 382,272 | SH | DFND | 1 | 382,272 | 0 | 0 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 14,252 | 787,410 | SH | SOLE | 0 | 787,410 | 0 | 0 | |
| Teradyne | COM | 880770102 | 41,530 | 1,042,412 | SH | DFND | 1 | 1,042,412 | 0 | 0 | |
| Teradyne | COM | 880770102 | 185,285 | 4,650,738 | SH | DFND | 2 | 3,856,537 | 0 | 794,201 | |
| Teradyne | COM | 880770102 | 85,871 | 2,155,402 | SH | SOLE | 0 | 2,085,590 | 0 | 69,812 | |
| Teradyne | COM | 880770102 | 28,991 | 727,681 | SH | DFND | 3 | 502,086 | 0 | 225,595 | |
| TerraForm Power | CL A COM | 88104R209 | 65 | 4,720 | SH | DFND | 2 | 4,720 | 0 | 0 | |
| TerraForm Power | CL A COM | 88104R209 | 57,926 | 4,215,900 | SH | DFND | 1 | 4,215,900 | 0 | 0 | |
| TerraForm Power | CL A COM | 88104R209 | 3,024 | 220,105 | SH | DFND | 3 | 220,105 | 0 | 0 | |
| Tesla Inc | COM | 88160R101 | 2,071,862 | 7,403,210 | SH | DFND | 2 | 2,140,870 | 0 | 5,262,340 | |
| Tesla Inc | COM | 88160R101 | 431,996 | 1,543,616 | SH | DFND | 1 | 1,543,616 | 0 | 0 | |
| Tesla Inc | COM | 88160R101 | 87,072 | 311,126 | SH | DFND | 3 | 190,428 | 0 | 120,698 | |
| Tesla Inc | COM | 88160R101 | 1,115,683 | 3,986,574 | SH | SOLE | 0 | 3,299,992 | 0 | 686,582 | |
| The Trade Desk | COM CL A | 88339J105 | 135,125 | 682,624 | SH | DFND | 1 | 682,624 | 0 | 0 | |
| The Trade Desk | COM CL A | 88339J105 | 70,921 | 358,278 | SH | DFND | 2 | 19,902 | 0 | 338,376 | |
| The Trade Desk | COM CL A | 88339J105 | 1,148 | 5,799 | SH | DFND | 3 | 5,799 | 0 | 0 | |
| The Trade Desk | COM CL A | 88339J105 | 47,591 | 240,418 | SH | SOLE | 0 | 240,418 | 0 | 0 | |
| Thermo Fisher Scientific | COM | 883556102 | 90,356 | 330,104 | SH | DFND | 1 | 330,104 | 0 | 0 | |
| Thermo Fisher Scientific | COM | 883556102 | 295,958 | 1,081,244 | SH | DFND | 2 | 824,703 | 0 | 256,541 | |
| Thermo Fisher Scientific | COM | 883556102 | 194,727 | 711,411 | SH | SOLE | 0 | 688,926 | 0 | 22,485 | |
| Thermo Fisher Scientific | COM | 883556102 | 64,498 | 235,635 | SH | DFND | 3 | 162,553 | 0 | 73,082 | |
| Trupanion | COM | 898202106 | 6,469 | 197,600 | SH | DFND | 1 | 197,600 | 0 | 0 | |
| Trupanion | COM | 898202106 | 2,690 | 82,166 | SH | DFND | 3 | 82,166 | 0 | 0 | |
| Trupanion | COM | 898202106 | 10,395 | 317,494 | SH | DFND | 2 | 102,671 | 0 | 214,823 | |
| Trupanion | COM | 898202106 | 24,064 | 735,000 | SH | SOLE | 0 | 735,000 | 0 | 0 | |
| United Parcel Service | CL B | 911312106 | 14,006 | 125,349 | SH | DFND | 1 | 125,349 | 0 | 0 | |
| United Parcel Service | CL B | 911312106 | 1,131 | 10,121 | SH | DFND | 2 | 0 | 0 | 10,121 | |
| United Parcel Service | CL B | 911312106 | 14,093 | 126,121 | SH | SOLE | 0 | 126,121 | 0 | 0 | |
| Unity Biotechnology Inc | COM | 91381U101 | 2,011 | 248,000 | SH | DFND | 1 | 248,000 | 0 | 0 | |
| Unity Biotechnology Inc | COM | 91381U101 | 28,831 | 3,555,014 | SH | SOLE | 0 | 3,555,014 | 0 | 0 | |
| Uxin ADR | ADS | 91818X108 | 4,592 | 1,211,500 | SH | DFND | 1 | 1,211,500 | 0 | 0 | |
| Uxin ADR | ADS | 91818X108 | 2,140 | 564,600 | SH | SOLE | 0 | 564,600 | 0 | 0 | |
| Vale SA ADR | ADR | 91912E105 | 119,624 | 9,159,600 | SH | DFND | 2 | 3,526,400 | 0 | 5,633,200 | |
| Vale SA ADR | ADR | 91912E105 | 18,207 | 1,394,100 | SH | DFND | 1 | 1,394,100 | 0 | 0 | |
| Varian Medical Systems Inc | COM | 92220P105 | 15,434 | 108,904 | SH | DFND | 2 | 108,904 | 0 | 0 | |
| Veeco Instruments | COM | 922417100 | 6,361 | 586,854 | SH | DFND | 1 | 586,854 | 0 | 0 | |
| Veeco Instruments | COM | 922417100 | 2,366 | 218,299 | SH | DFND | 2 | 67,206 | 0 | 151,093 | |
| Veeco Instruments | COM | 922417100 | 633 | 58,435 | SH | DFND | 3 | 58,435 | 0 | 0 | |
| Veeco Instruments | COM | 922417100 | 8,360 | 771,205 | SH | SOLE | 0 | 771,205 | 0 | 0 | |
| Verisk Analytics | COM | 92345Y106 | 46,458 | 349,311 | SH | DFND | 3 | 241,679 | 0 | 107,632 | |
| Verisk Analytics | COM | 92345Y106 | 221,683 | 1,666,789 | SH | DFND | 2 | 1,276,091 | 0 | 390,698 | |
| Verisk Analytics | COM | 92345Y106 | 64,775 | 487,032 | SH | DFND | 1 | 487,032 | 0 | 0 | |
| Verisk Analytics | COM | 92345Y106 | 142,634 | 1,072,433 | SH | SOLE | 0 | 1,039,740 | 0 | 32,693 | |
| Vertex Pharmaceuticals | COM | 92532F100 | 36,668 | 199,337 | SH | DFND | 1 | 199,337 | 0 | 0 | |
| Vertex Pharmaceuticals | COM | 92532F100 | 28,933 | 157,285 | SH | DFND | 2 | 54,379 | 0 | 102,906 | |
| Vertex Pharmaceuticals | COM | 92532F100 | 164 | 889 | SH | DFND | 3 | 889 | 0 | 0 | |
| Vertex Pharmaceuticals | COM | 92532F100 | 12,386 | 67,334 | SH | SOLE | 0 | 67,334 | 0 | 0 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 135,629 | 868,357 | SH | DFND | 1 | 868,357 | 0 | 0 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 280,771 | 1,797,626 | SH | SOLE | 0 | 1,739,887 | 0 | 57,739 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 425,369 | 2,723,408 | SH | DFND | 2 | 2,048,416 | 0 | 674,992 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 94,852 | 607,286 | SH | DFND | 3 | 418,190 | 0 | 189,096 | |
| Voya Prime Rate Trust | SH BEN INT | 92913A100 | 2,729 | 571,000 | SH | DFND | 1 | 571,000 | 0 | 0 | |
| Voya Prime Rate Trust | SH BEN INT | 92913A100 | 924 | 193,400 | SH | DFND | 3 | 193,400 | 0 | 0 | |
| WEC Energy Group | COM | 92939U106 | 36 | 450 | SH | DFND | 2 | 450 | 0 | 0 | |
| WEC Energy Group | COM | 92939U106 | 25,997 | 328,740 | SH | DFND | 1 | 328,740 | 0 | 0 | |
| WEC Energy Group | COM | 92939U106 | 1,061 | 13,423 | SH | DFND | 3 | 13,423 | 0 | 0 | |
| Wabtec | COM | 929740108 | 163,800 | 2,221,919 | SH | DFND | 2 | 1,506,387 | 0 | 715,532 | |
| Wabtec | COM | 929740108 | 82,210 | 1,115,163 | SH | DFND | 1 | 1,115,163 | 0 | 0 | |
| Wabtec | COM | 929740108 | 29,232 | 396,525 | SH | DFND | 3 | 272,263 | 0 | 124,262 | |
| Wabtec | COM | 929740108 | 99,518 | 1,349,952 | SH | SOLE | 0 | 1,312,771 | 0 | 37,181 | |
| Waters | COM | 941848103 | 91,188 | 362,275 | SH | DFND | 1 | 362,275 | 0 | 0 | |
| Waters | COM | 941848103 | 293,827 | 1,167,325 | SH | DFND | 2 | 904,546 | 0 | 262,779 | |
| Waters | COM | 941848103 | 61,856 | 245,742 | SH | DFND | 3 | 169,740 | 0 | 76,002 | |
| Waters | COM | 941848103 | 182,650 | 725,635 | SH | SOLE | 0 | 702,786 | 0 | 22,849 | |
| Watsco Inc | COM | 942622200 | 76,959 | 537,387 | SH | DFND | 1 | 537,387 | 0 | 0 | |
| Watsco Inc | COM | 942622200 | 54,818 | 382,784 | SH | DFND | 2 | 121,824 | 0 | 260,960 | |
| Watsco Inc | COM | 942622200 | 28,698 | 200,390 | SH | SOLE | 0 | 200,390 | 0 | 0 | |
| Watsco Inc | COM | 942622200 | 1,005 | 7,015 | SH | DFND | 3 | 7,015 | 0 | 0 | |
| Wayfair Inc Class A | CL A | 94419L101 | 249,292 | 1,679,299 | SH | DFND | 1 | 1,679,299 | 0 | 0 | |
| Wayfair Inc Class A | CL A | 94419L101 | 154,890 | 1,043,379 | SH | DFND | 2 | 124,417 | 0 | 918,962 | |
| Wayfair Inc Class A | CL A | 94419L101 | 11,943 | 80,453 | SH | DFND | 3 | 80,453 | 0 | 0 | |
| Wayfair Inc Class A | CL A | 94419L101 | 102,622 | 691,290 | SH | SOLE | 0 | 691,290 | 0 | 0 | |
| Weibo Corp SPON ADR | SPONSORED ADR | 948596101 | 1,631 | 26,310 | SH | DFND | 3 | 0 | 0 | 26,310 | |
| Wipro Ltd ADR | SPON ADR 1 SH | 97651M109 | 538 | 135,210 | SH | DFND | 2 | 100,842 | 0 | 34,368 | |
| Wix Com | SHS | M98068105 | 298,771 | 2,472,656 | SH | DFND | 2 | 730,347 | 0 | 1,742,309 | |
| Workday Inc | CL A | 98138H101 | 86,039 | 446,144 | SH | DFND | 1 | 446,144 | 0 | 0 | |
| Workday Inc | CL A | 98138H101 | 25,702 | 133,276 | SH | DFND | 3 | 56,286 | 0 | 76,990 | |
| Workday Inc | CL A | 98138H101 | 525,461 | 2,724,711 | SH | DFND | 2 | 967,097 | 0 | 1,757,614 | |
| Workday Inc | CL A | 98138H101 | 352,094 | 1,825,742 | SH | SOLE | 0 | 1,332,007 | 0 | 493,735 | |
| Xylem | COM | 98419M100 | 3,930 | 49,719 | SH | DFND | 1 | 49,719 | 0 | 0 | |
| Xylem | COM | 98419M100 | 970 | 12,273 | SH | DFND | 3 | 12,273 | 0 | 0 | |
| Xylem | COM | 98419M100 | 7,475 | 94,578 | SH | DFND | 2 | 58,203 | 0 | 36,375 | |
| Yext Inc | COM | 98585N106 | 66,070 | 3,022,400 | SH | DFND | 1 | 3,022,400 | 0 | 0 | |
| Yext Inc | COM | 98585N106 | 33,310 | 1,523,804 | SH | SOLE | 0 | 1,523,804 | 0 | 0 | |
| Yext Inc | COM | 98585N106 | 5,184 | 237,135 | SH | DFND | 3 | 237,135 | 0 | 0 | |
| Yext Inc | COM | 98585N106 | 42,937 | 1,964,180 | SH | DFND | 2 | 341,361 | 0 | 1,622,819 | |
| Zai Lab ADR | ADR | 98887Q104 | 1,260 | 42,700 | SH | DFND | 1 | 42,700 | 0 | 0 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 1,964 | 57,439 | SH | DFND | 1 | 57,439 | 0 | 0 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 20,042 | 586,022 | SH | DFND | 2 | 405,026 | 0 | 180,996 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 2,894 | 84,618 | SH | DFND | 3 | 60,648 | 0 | 23,970 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 12,081 | 353,235 | SH | SOLE | 0 | 340,416 | 0 | 12,819 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 74,106 | 2,133,171 | SH | DFND | 1 | 2,133,171 | 0 | 0 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 167,938 | 4,834,128 | SH | DFND | 2 | 3,243,907 | 0 | 1,590,221 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 114,663 | 3,300,618 | SH | SOLE | 0 | 3,216,209 | 0 | 84,409 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 40,571 | 1,167,852 | SH | DFND | 3 | 862,403 | 0 | 305,449 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 8,270 | 412,879 | SH | DFND | 1 | 412,879 | 0 | 0 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 1,742 | 86,955 | SH | DFND | 3 | 86,955 | 0 | 0 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 6,630 | 330,987 | SH | DFND | 2 | 106,503 | 0 | 224,484 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 4,914 | 245,311 | SH | SOLE | 0 | 245,311 | 0 | 0 | |
| iRobot | COM | 462726100 | 18,534 | 157,481 | SH | DFND | 1 | 157,481 | 0 | 0 | |
| iRobot | COM | 462726100 | 39,101 | 332,235 | SH | SOLE | 0 | 332,235 | 0 | 0 | |
| iRobot | COM | 462726100 | 6,675 | 56,715 | SH | DFND | 3 | 56,715 | 0 | 0 | |
| iRobot | COM | 462726100 | 23,063 | 195,960 | SH | DFND | 2 | 63,872 | 0 | 132,088 | |