The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101 17,201 90,281 SH   SOLE   90,281 0 0
58 COM INC SPON ADR REP A 31680Q104 7,318 135,000 SH   SOLE   135,000 0 0
ABBOTT LABS COM 002824100 44,311 612,644 SH   SOLE   612,644 0 0
ABBVIE INC COM 00287Y109 50,458 547,354 SH   SOLE   547,354 0 0
ABIOMED INC COM 003654100 983 3,024 SH   SOLE   3,024 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 2,809 173,700 SH   SOLE   173,700 0 0
ACCELERON PHARMA INC COM 00434H108 10,572 242,758 SH   SOLE   242,758 0 0
ACCURAY INC COM 004397105 283 82,853 SH   SOLE   82,853 0 0
ACHILLION PHARMACEUTICALS IN COM 00448Q201 1,153 725,000 SH   SOLE   725,000 0 0
ACTIVISION BLIZZARD INC COM 00507V109 11,126 238,918 SH   SOLE   238,918 0 0
ADOBE INC COM 00724F101 33,162 146,585 SH   SOLE   146,585 0 0
ADTALEM GLOBAL ED INC COM 00737L103 379 8,000 SH   SOLE   8,000 0 0
ADVANCE AUTO PARTS INC COM 00751Y106 718 4,560 SH   SOLE   4,560 0 0
ADVANCED MICRO DEVICES INC COM 007903107 9,750 528,206 SH   SOLE   528,206 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 17,284 478,800 SH   SOLE   478,800 0 0
AES CORP COM 00130H105 1,337 92,443 SH   SOLE   92,443 0 0
AFFILIATED MANAGERS GROUP COM 008252108 263 2,700 SH   SOLE   2,700 0 0
AFLAC INC COM 001055102 3 64 SH   OTR 1 0 0 64
AFLAC INC COM 001055102 4,508 98,954 SH   SOLE   98,954 0 0
AGILENT TECHNOLOGIES INC COM 00846U101 30,076 445,858 SH   SOLE   445,858 0 0
AGNC INVT CORP COM 00123Q104 907 51,692 SH   SOLE   51,692 0 0
AGNICO EAGLE MINES LTD COM 008474108 1,213 30,033 SH   SOLE   30,033 0 0
AIR PRODS & CHEMS INC COM 009158106 1 7 SH   OTR 1 0 0 7
AIR PRODS & CHEMS INC COM 009158106 16,857 105,331 SH   SOLE   105,331 0 0
AKAMAI TECHNOLOGIES INC COM 00971T101 3,220 52,713 SH   SOLE   52,713 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 1,659 300,000 SH   SOLE   300,000 0 0
AKERS BIOSCIENCES INC COM NEW 00973E300 367 324,999 SH   SOLE   324,999 0 0
ALAMOS GOLD INC NEW COM CL A 011532108 416 115,492 SH   SOLE   115,492 0 0
ALBEMARLE CORP COM 012653101 572 7,419 SH   SOLE   7,419 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 2,332 227,500 SH   SOLE   227,500 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 60,935 625,897 SH   SOLE   625,897 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 78,729 574,395 SH   SOLE   574,395 0 0
ALIGN TECHNOLOGY INC COM 016255101 1,175 5,609 SH   SOLE   5,609 0 0
ALLIANCE DATA SYSTEMS CORP COM 018581108 3,381 22,526 SH   SOLE   22,526 0 0
ALLSCRIPTS HEALTHCARE SOLUTN COM 01988P108 337 35,000 SH   SOLE   35,000 0 0
ALLSTATE CORP COM 020002101 1 13 SH   OTR 1 0 0 13
ALLSTATE CORP COM 020002101 21,430 259,366 SH   SOLE   259,366 0 0
ALLY FINL INC COM 02005N100 1,503 66,348 SH   SOLE   66,348 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 20,757 284,701 SH   SOLE   284,701 0 0
ALPHABET INC CAP STK CL A 02079K305 1 1 SH   OTR 1 0 0 1
ALPHABET INC CAP STK CL A 02079K305 101,302 96,948 SH   SOLE   96,948 0 0
ALPHABET INC CAP STK CL C 02079K107 35,879 34,647 SH   SOLE   34,647 0 0
ALTRIA GROUP INC COM 02209S103 404 8,180 SH   SOLE   8,180 0 0
AMAZON COM INC COM 023135106 127,553 84,928 SH   SOLE   84,928 0 0
AMBARELLA INC SHS G037AX101 8,796 251,480 SH   SOLE   251,480 0 0
AMBEV SA SPONSORED ADR 02319V103 152 38,730 SH   SOLE   38,730 0 0
AMERCO COM 023586100 372 1,133 SH   SOLE   1,133 0 0
AMERICA MOVIL SAB DE CV SPON ADR L SHS 02364W105 193 13,570 SH   SOLE   13,570 0 0
AMERICAN EXPRESS CO COM 025816109 1 15 SH   OTR 1 0 0 15
AMERICAN EXPRESS CO COM 025816109 34,504 361,993 SH   SOLE   361,993 0 0
AMERICAN INTL GROUP INC COM NEW 026874784 2,443 61,986 SH   SOLE   61,986 0 0
AMERICAN TOWER CORP NEW COM 03027X100 6,926 43,782 SH   SOLE   43,782 0 0
AMERICAN WTR WKS CO INC NEW COM 030420103 7,372 81,217 SH   SOLE   81,217 0 0
AMERIPRISE FINL INC COM 03076C106 8,502 81,466 SH   SOLE   81,466 0 0
AMERIPRISE FINL INC COM 03076C106 1 10 SH   OTR 1 0 0 10
AMERISOURCEBERGEN CORP COM 03073E105 2,146 28,845 SH   SOLE   28,845 0 0
AMETEK INC NEW COM 031100100 2,343 34,605 SH   SOLE   34,605 0 0
AMGEN INC COM 031162100 1 6 SH   OTR 1 0 0 6
AMGEN INC COM 031162100 190,100 976,569 SH   SOLE   976,569 0 0
AMICUS THERAPEUTICS INC COM 03152W109 5,709 596,000 SH   SOLE   596,000 0 0
AMPHENOL CORP NEW CL A 032095101 2,024 24,977 SH   SOLE   24,977 0 0
ANADARKO PETE CORP COM 032511107 4,841 110,436 SH   SOLE   110,436 0 0
ANALOG DEVICES INC COM 032654105 11,199 130,481 SH   SOLE   130,481 0 0
ANAPTYSBIO INC COM 032724106 4,465 70,000 SH   SOLE   70,000 0 0
ANGIODYNAMICS INC COM 03475V101 1,127 56,000 SH   SOLE   56,000 0 0
ANHEUSER BUSCH INBEV SA/NV SPONSORED ADR 03524A108 296 4,500 SH   SOLE   4,500 0 0
ANNALY CAP MGMT INC COM 035710409 2,286 232,760 SH   SOLE   232,760 0 0
ANSYS INC COM 03662Q105 1,020 7,134 SH   SOLE   7,134 0 0
ANTHEM INC COM 036752103 18,771 71,475 SH   SOLE   71,475 0 0
APACHE CORP COM 037411105 7,645 291,261 SH   SOLE   291,261 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 6,960 527,700 SH   SOLE   527,700 0 0
APHRIA INC COM 03765K104 63 11,000 SH   SOLE   11,000 0 0
APPLE INC COM 037833100 5 31 SH   OTR 1 0 0 31
APPLE INC COM 037833100 113,351 718,625 SH   SOLE   718,625 0 0
APPLIED MATLS INC COM 038222105 1 30 SH   OTR 1 0 0 30
APPLIED MATLS INC COM 038222105 33,208 1,014,337 SH   SOLE   1,014,337 0 0
ARBUTUS BIOPHARMA CORP COM 03879J100 402 105,000 SH   SOLE   105,000 0 0
ARCH CAP GROUP LTD ORD G0450A105 822 30,781 SH   SOLE   30,781 0 0
ARCHER DANIELS MIDLAND CO COM 039483102 2,318 56,573 SH   SOLE   56,573 0 0
ARCONIC INC COM 03965L100 568 33,712 SH   SOLE   33,712 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 10,820 277,800 SH   SOLE   277,800 0 0
ARISTA NETWORKS INC COM 040413106 17,818 84,571 SH   SOLE   84,571 0 0
ARQULE INC COM 04269E107 3,226 1,164,728 SH   SOLE   1,164,728 0 0
ARRAY BIOPHARMA INC COM 04269X105 23,921 1,678,710 SH   SOLE   1,678,710 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 7,377 594,000 SH   SOLE   594,000 0 0
ASE TECHNOLOGY HOLDING CO LT SPONSORED ADS 00215W100 433 115,445 SH   SOLE   115,445 0 0
ASPEN INSURANCE HOLDINGS LTD SHS G05384105 4,476 106,600 SH   SOLE   106,600 0 0
ASSURANT INC COM 04621X108 1,103 12,330 SH   SOLE   12,330 0 0
AT&T INC COM 00206R102 4 129 SH   OTR 1 0 0 129
AT&T INC COM 00206R102 40,596 1,422,474 SH   SOLE   1,422,474 0 0
ATHENAHEALTH INC COM 04685W103 6,743 51,115 SH   SOLE   51,115 0 0
ATHENE HLDG LTD CL A G0684D107 534 13,419 SH   SOLE   13,419 0 0
ATMOS ENERGY CORP COM 049560105 1 12 SH   OTR 1 0 0 12
ATMOS ENERGY CORP COM 049560105 2,993 32,281 SH   SOLE   32,281 0 0
AU OPTRONICS CORP SPONSORED ADR 002255107 380 96,327 SH   SOLE   96,327 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 6,413 300,800 SH   SOLE   300,800 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 1,074 157,500 SH   SOLE   157,500 0 0
AURORA CANNABIS INC COM 05156X108 62 12,405 SH   SOLE   12,405 0 0
AUTODESK INC COM 052769106 21,018 163,432 SH   SOLE   163,432 0 0
AUTOLIV INC COM 052800109 1,730 24,638 SH   SOLE   24,638 0 0
AUTOMATIC DATA PROCESSING IN COM 053015103 11,853 90,405 SH   SOLE   90,405 0 0
AUTOZONE INC COM 053332102 1,794 2,140 SH   SOLE   2,140 0 0
AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 160 62,000 SH   SOLE   62,000 0 0
AVALONBAY CMNTYS INC COM 053484101 2 9 SH   OTR 1 0 0 9
AVALONBAY CMNTYS INC COM 053484101 1,917 11,017 SH   SOLE   11,017 0 0
AVISTA CORP COM 05379B107 5,212 122,700 SH   SOLE   122,700 0 0
AXA EQUITABLE HLDGS INC COM 054561105 570 34,254 SH   SOLE   34,254 0 0
AZUL S A SPONSR ADR PFD 05501U106 13,872 501,000 SH   SOLE   501,000 0 0
BAIDU INC SPON ADR REP A 056752108 15,363 96,874 SH   SOLE   96,874 0 0
BAKER HUGHES A GE CO CL A 05722G100 2,308 107,331 SH   SOLE   107,331 0 0
BALL CORP COM 058498106 3,459 75,241 SH   SOLE   75,241 0 0
BANCO BRADESCO S A SP ADR PFD NEW 059460303 1,164 117,691 SH   SOLE   117,691 0 0
BANCO SANTANDER SA ADR 05964H105 3 781 SH   OTR 1 0 0 781
BANCOLOMBIA S A SPON ADR PREF 05968L102 241 6,314 SH   SOLE   6,314 0 0
BANK AMER CORP COM 060505104 15,476 628,104 SH   SOLE   628,104 0 0
BANK MONTREAL QUE COM 063671101 3,224 49,365 SH   SOLE   49,365 0 0
BANK N S HALIFAX COM 064149107 5,209 104,553 SH   SOLE   104,553 0 0
BANK NEW YORK MELLON CORP COM 064058100 4,953 105,221 SH   SOLE   105,221 0 0
BARRICK GOLD CORP COM 067901108 638 47,277 SH   SOLE   47,277 0 0
BAXTER INTL INC COM 071813109 3,219 48,913 SH   SOLE   48,913 0 0
BB&T CORP COM 054937107 2,994 69,116 SH   SOLE   69,116 0 0
BCE INC COM NEW 05534B760 5,384 136,365 SH   SOLE   136,365 0 0
BECTON DICKINSON & CO COM 075887109 12,780 56,720 SH   SOLE   56,720 0 0
BEIGENE LTD SPONSORED ADR 07725L102 20,728 147,788 SH   SOLE   147,788 0 0
BEMIS INC COM 081437105 505 11,000 SH   SOLE   11,000 0 0
BENEFITFOCUS INC COM 08180D106 914 20,000 SH   SOLE   20,000 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 7 33 SH   OTR 1 0 0 33
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 42,934 210,286 SH   SOLE   210,286 0 0
BEST BUY INC COM 086516101 1,665 31,436 SH   SOLE   31,436 0 0
BHP GROUP LIMITED SPONSORED ADS 088606108 3 68 SH   OTR 1 0 0 68
BIO RAD LABS INC CL A 090572207 10,052 43,290 SH   SOLE   43,290 0 0
BIO TECHNE CORP COM 09073M104 12,227 84,489 SH   SOLE   84,489 0 0
BIOGEN INC COM 09062X103 171,439 569,741 SH   SOLE   569,741 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 20,257 547,799 SH   SOLE   547,799 0 0
BIOLIFE SOLUTIONS INC COM NEW 09062W204 914 76,000 SH   SOLE   76,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 39,155 459,852 SH   SOLE   459,852 0 0
BIOMARIN PHARMACEUTICAL INC NOTE 1.500%10/1 09061GAF8 223 200 PRN   SOLE   200 0 0
BLACKROCK INC COM 09247X101 3,554 9,048 SH   SOLE   9,048 0 0
BLOCK H & R INC COM 093671105 702 27,679 SH   SOLE   27,679 0 0
BLUE HILLS BANCORP INC COM 095573101 3,791 177,663 SH   SOLE   177,663 0 0
BLUEBIRD BIO INC COM 09609G100 16,774 169,100 SH   SOLE   169,100 0 0
BOEING CO COM 097023105 9,292 28,814 SH   SOLE   28,814 0 0
BOOKING HLDGS INC COM 09857L108 9,426 5,473 SH   SOLE   5,473 0 0
BORGWARNER INC COM 099724106 6,830 196,603 SH   SOLE   196,603 0 0
BOSTON PROPERTIES INC COM 101121101 1,709 15,181 SH   SOLE   15,181 0 0
BOSTON SCIENTIFIC CORP COM 101137107 3,753 106,194 SH   SOLE   106,194 0 0
BRINKER INTL INC COM 109641100 440 10,000 SH   SOLE   10,000 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 70,820 1,362,502 SH   SOLE   1,362,502 0 0
BROADCOM INC COM 11135F101 31,678 124,584 SH   SOLE   124,584 0 0
BROADRIDGE FINL SOLUTIONS IN COM 11133T103 1 10 SH   OTR 1 0 0 10
BROOKFIELD ASSET MGMT INC CL A LTD VT SH 112585104 5,459 142,506 SH   SOLE   142,506 0 0
BROWN FORMAN CORP CL B 115637209 1,095 23,011 SH   SOLE   23,011 0 0
BUNGE LIMITED COM G16962105 692 12,957 SH   SOLE   12,957 0 0
C H ROBINSON WORLDWIDE INC COM NEW 12541W209 2,048 24,355 SH   SOLE   24,355 0 0
CABOT OIL & GAS CORP COM 127097103 719 32,190 SH   SOLE   32,190 0 0
CADENCE DESIGN SYSTEM INC COM 127387108 3,596 82,699 SH   SOLE   82,699 0 0
CAE INC COM 124765108 608 33,101 SH   SOLE   33,101 0 0
CALITHERA BIOSCIENCES INC COM 13089P101 722 180,000 SH   SOLE   180,000 0 0
CAMPBELL SOUP CO COM 134429109 1,920 58,204 SH   SOLE   58,204 0 0
CANADIAN NAT RES LTD COM 136385101 1,935 80,238 SH   SOLE   80,238 0 0
CANADIAN NATL RY CO COM 136375102 5,560 75,102 SH   SOLE   75,102 0 0
CANADIAN PAC RY LTD COM 13645T100 1,373 7,744 SH   SOLE   7,744 0 0
CANON INC SPONSORED ADR 138006309 3 93 SH   OTR 1 0 0 93
CANON INC SPONSORED ADR 138006309 565 20,493 SH   SOLE   20,493 0 0
CAPITAL ONE FINL CORP COM 14040H105 10,846 143,488 SH   SOLE   143,488 0 0
CARDINAL HEALTH INC COM 14149Y108 1,166 26,154 SH   SOLE   26,154 0 0
CARLISLE COS INC COM 142339100 8,414 83,705 SH   SOLE   83,705 0 0
CARMAX INC COM 143130102 802 12,782 SH   SOLE   12,782 0 0
CARNIVAL CORP UNIT 99/99/9999 143658300 11,569 234,677 SH   SOLE   234,677 0 0
CATERPILLAR INC DEL COM 149123101 9,875 77,716 SH   SOLE   77,716 0 0
CBOE GLOBAL MARKETS INC COM 12503M108 696 7,113 SH   SOLE   7,113 0 0
CBRE GROUP INC CL A 12504L109 1 26 SH   OTR 1 0 0 26
CBRE GROUP INC CL A 12504L109 11,064 276,345 SH   SOLE   276,345 0 0
CBS CORP NEW CL B 124857202 5,866 134,183 SH   SOLE   134,183 0 0
CDK GLOBAL INC COM 12508E101 3,091 64,567 SH   SOLE   64,567 0 0
CDN IMPERIAL BK COMM TORONTO COM 136069101 6,755 90,738 SH   SOLE   90,738 0 0
CDW CORP COM 12514G108 1,618 19,962 SH   SOLE   19,962 0 0
CELGENE CORP COM 151020104 135,309 2,111,324 SH   SOLE   2,111,324 0 0
CEMEX SAB DE CV NOTE 3.720% 3/1 151290BT9 1,481 1,500 PRN   SOLE   1,500 0 0
CEMEX SAB DE CV SPON ADR NEW 151290889 691 143,405 SH   SOLE   143,405 0 0
CENOVUS ENERGY INC COM 15135U109 232 33,012 SH   SOLE   33,012 0 0
CENTENE CORP DEL COM 15135B101 1,496 12,972 SH   SOLE   12,972 0 0
CENTERPOINT ENERGY INC COM 15189T107 1 39 SH   OTR 1 0 0 39
CENTERPOINT ENERGY INC COM 15189T107 8,791 311,431 SH   SOLE   311,431 0 0
CENTURYLINK INC COM 156700106 2,688 177,444 SH   SOLE   177,444 0 0
CERNER CORP COM 156782104 5,315 101,357 SH   SOLE   101,357 0 0
CEVA INC COM 157210105 6,656 301,310 SH   SOLE   301,310 0 0
CF INDS HLDGS INC COM 125269100 6,004 137,988 SH   SOLE   137,988 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 7,651 26,850 SH   SOLE   26,850 0 0
CHENIERE ENERGY INC COM NEW 16411R208 1,819 30,735 SH   SOLE   30,735 0 0
CHEVRON CORP NEW COM 166764100 19,365 178,011 SH   SOLE   178,011 0 0
CHIASMA INC COM 16706W102 73 23,500 SH   SOLE   23,500 0 0
CHINA MOBILE LIMITED SPONSORED ADR 16941M109 817 17,030 SH   SOLE   17,030 0 0
CHIPOTLE MEXICAN GRILL INC COM 169656105 607 1,405 SH   SOLE   1,405 0 0
CHUBB LIMITED COM H1467J104 1 6 SH   OTR 1 0 0 6
CHURCH & DWIGHT INC COM 171340102 2,073 31,524 SH   SOLE   31,524 0 0
CHURCHILL DOWNS INC COM 171484108 366 1,500 SH   SOLE   1,500 0 0
CIGNA CORP NEW COM 125523100 0 2 SH   OTR 1 0 0 2
CIGNA CORP NEW COM 125523100 22,736 119,719 SH   SOLE   119,719 0 0
CIMAREX ENERGY CO COM 171798101 646 10,478 SH   SOLE   10,478 0 0
CINTAS CORP COM 172908105 1,483 8,828 SH   SOLE   8,828 0 0
CIRRUS LOGIC INC COM 172755100 431 13,000 SH   SOLE   13,000 0 0
CISCO SYS INC COM 17275R102 1 28 SH   OTR 1 0 0 28
CISCO SYS INC COM 17275R102 41,986 969,037 SH   SOLE   969,037 0 0
CIT GROUP INC COM NEW 125581801 786 20,539 SH   SOLE   20,539 0 0
CITIGROUP INC COM NEW 172967424 3 51 SH   OTR 1 0 0 51
CITIGROUP INC COM NEW 172967424 30,167 579,494 SH   SOLE   579,494 0 0
CITIZENS FINL GROUP INC COM 174610105 5,944 199,928 SH   SOLE   199,928 0 0
CITRIX SYS INC COM 177376100 1 8 SH   OTR 1 0 0 8
CITRIX SYS INC COM 177376100 19,787 193,126 SH   SOLE   193,126 0 0
CITRIX SYS INC NOTE 0.500% 4/1 177376AD2 355 250 PRN   SOLE   250 0 0
CLOROX CO DEL COM 189054109 1,597 10,358 SH   SOLE   10,358 0 0
CLOVIS ONCOLOGY INC COM 189464100 5,264 293,100 SH   SOLE   293,100 0 0
CME GROUP INC COM CL A 12572Q105 5,455 29,001 SH   SOLE   29,001 0 0
COCA COLA CO COM 191216100 1 20 SH   OTR 1 0 0 20
COCA COLA CO COM 191216100 15,380 324,841 SH   SOLE   324,841 0 0
COGNEX CORP COM 192422103 333 8,611 SH   SOLE   8,611 0 0
COGNIZANT TECHNOLOGY SOLUTIO CL A 192446102 2,749 43,305 SH   SOLE   43,305 0 0
COLGATE PALMOLIVE CO COM 194162103 15,444 259,482 SH   SOLE   259,482 0 0
COLGATE PALMOLIVE CO COM 194162103 1 12 SH   OTR 1 0 0 12
COMCAST CORP NEW CL A 20030N101 30,930 908,404 SH   SOLE   908,404 0 0
COMERICA INC COM 200340107 5,668 82,513 SH   SOLE   82,513 0 0
COMPANHIA ENERGETICA DE MINA SP ADR N-V PFD 204409601 215 60,296 SH   SOLE   60,296 0 0
CONAGRA BRANDS INC COM 205887102 912 42,702 SH   SOLE   42,702 0 0
CONCHO RES INC COM 20605P101 7,674 74,658 SH   SOLE   74,658 0 0
CONOCOPHILLIPS COM 20825C104 15,742 252,488 SH   SOLE   252,488 0 0
CONSOLIDATED EDISON INC COM 209115104 10,148 132,724 SH   SOLE   132,724 0 0
CONSTELLATION BRANDS INC CL A 21036P108 2,130 13,248 SH   SOLE   13,248 0 0
CORNING INC COM 219350105 2,068 68,442 SH   SOLE   68,442 0 0
COSTAR GROUP INC COM 22160N109 903 2,677 SH   SOLE   2,677 0 0
COSTCO WHSL CORP NEW COM 22160K105 6,566 32,234 SH   SOLE   32,234 0 0
COTY INC COM CL A 222070203 5,841 890,454 SH   SOLE   890,454 0 0
CREDICORP LTD COM G2519Y108 19,573 88,300 SH   SOLE   88,300 0 0
CROWN CASTLE INTL CORP NEW COM 22822V101 3,382 31,138 SH   SOLE   31,138 0 0
CRYOLIFE INC COM 228903100 1,277 45,000 SH   SOLE   45,000 0 0
CSX CORP COM 126408103 4,843 77,946 SH   SOLE   77,946 0 0
CTRIP COM INTL LTD AMERICAN DEP SHS 22943F100 358 13,245 SH   SOLE   13,245 0 0
CTRIP COM INTL LTD NOTE 1.000% 7/0 22943FAF7 1,957 2,100 PRN   SOLE   2,100 0 0
CTRIP COM INTL LTD NOTE 1.990% 7/0 22943FAH3 969 1,000 PRN   SOLE   1,000 0 0
CUMMINS INC COM 231021106 10,866 81,308 SH   SOLE   81,308 0 0
CVS HEALTH CORP COM 126650100 1 16 SH   OTR 1 0 0 16
CVS HEALTH CORP COM 126650100 10,521 160,586 SH   SOLE   160,586 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 7,697 978,000 SH   SOLE   978,000 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 7,414 490,988 SH   SOLE   490,988 0 0
D R HORTON INC COM 23331A109 9,679 279,262 SH   SOLE   279,262 0 0
DANAHER CORP DEL COM 235851102 43,030 417,295 SH   SOLE   417,295 0 0
DANAHER CORP DEL COM 235851102 2 19 SH   OTR 1 0 0 19
DARDEN RESTAURANTS INC COM 237194105 1,834 18,363 SH   SOLE   18,363 0 0
DAVITA INC COM 23918K108 2,969 57,689 SH   SOLE   57,689 0 0
DECKERS OUTDOOR CORP COM 243537107 512 4,000 SH   SOLE   4,000 0 0
DEERE & CO COM 244199105 12,345 82,760 SH   SOLE   82,760 0 0
DELL TECHNOLOGIES INC CL C 24703L202 2,115 43,270 SH   SOLE   43,270 0 0
DELTA AIR LINES INC DEL COM NEW 247361702 1,474 29,542 SH   SOLE   29,542 0 0
DENTSPLY SIRONA INC COM 24906P109 5,163 138,762 SH   SOLE   138,762 0 0
DEVON ENERGY CORP NEW COM 25179M103 4,154 184,298 SH   SOLE   184,298 0 0
DEXCOM INC COM 252131107 598 4,988 SH   SOLE   4,988 0 0
DIAMONDBACK ENERGY INC COM 25278X109 798 8,614 SH   SOLE   8,614 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 4,784 447,500 SH   SOLE   447,500 0 0
DIGITAL RLTY TR INC COM 253868103 1,486 13,948 SH   SOLE   13,948 0 0
DISCOVER FINL SVCS COM 254709108 14,263 241,839 SH   SOLE   241,839 0 0
DISCOVERY INC COM SER A 25470F104 1,117 45,169 SH   SOLE   45,169 0 0
DISCOVERY INC COM SER C 25470F302 1,116 48,356 SH   SOLE   48,356 0 0
DISH NETWORK CORP CL A 25470M109 2,036 81,546 SH   SOLE   81,546 0 0
DISNEY WALT CO COM DISNEY 254687106 4 33 SH   OTR 1 0 0 33
DISNEY WALT CO COM DISNEY 254687106 57,137 521,112 SH   SOLE   521,112 0 0
DOLLAR GEN CORP NEW COM 256677105 10,136 93,782 SH   SOLE   93,782 0 0
DOLLAR TREE INC COM 256746108 1,480 16,382 SH   SOLE   16,382 0 0
DOMINION ENERGY INC COM 25746U109 2 28 SH   OTR 1 0 0 28
DOMINION ENERGY INC COM 25746U109 5,110 71,508 SH   SOLE   71,508 0 0
DOMINION ENERGY MIDSTRM PRTN COM UT REP LTD 257454108 2,084 115,548 SH   SOLE   115,548 0 0
DOMINOS PIZZA INC COM 25754A201 848 3,421 SH   SOLE   3,421 0 0
DOVA PHARMACEUTICALS INC COM 25985T102 1,768 233,200 SH   SOLE   233,200 0 0
DOVER CORP COM 260003108 1,771 24,968 SH   SOLE   24,968 0 0
DOWDUPONT INC COM 26078J100 15,957 298,389 SH   SOLE   298,389 0 0
DOWDUPONT INC COM 26078J100 1 25 SH   OTR 1 0 0 25
DR REDDYS LABS LTD ADR 256135203 679 18,000 SH   SOLE   18,000 0 0
DTE ENERGY CO COM 233331107 551 5,000 SH   SOLE   5,000 0 0
DUKE REALTY CORP COM NEW 264411505 1 29 SH   OTR 1 0 0 29
DUN & BRADSTREET CORP DEL NE COM 26483E100 4,539 31,800 SH   SOLE   31,800 0 0
DUNKIN BRANDS GROUP INC COM 265504100 449 7,000 SH   SOLE   7,000 0 0
DXC TECHNOLOGY CO COM 23355L106 1,171 22,022 SH   SOLE   22,022 0 0
E TRADE FINANCIAL CORP COM NEW 269246401 733 16,702 SH   SOLE   16,702 0 0
EAGLE PHARMACEUTICALS INC COM 269796108 967 24,000 SH   SOLE   24,000 0 0
EATON VANCE CORP COM NON VTG 278265103 1 29 SH   OTR 1 0 0 29
EBAY INC COM 278642103 7,857 279,918 SH   SOLE   279,918 0 0
ECOLAB INC COM 278865100 2 16 SH   OTR 1 0 0 16
ECOLAB INC COM 278865100 3,469 23,542 SH   SOLE   23,542 0 0
ECOPETROL S A SPONSORED ADS 279158109 1,175 74,000 SH   SOLE   74,000 0 0
EDISON INTL COM 281020107 11,402 200,847 SH   SOLE   200,847 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 3,615 23,603 SH   SOLE   23,603 0 0
EIDOS THERAPEUTICS INC COM 28249H104 1,995 145,000 SH   SOLE   145,000 0 0
ELECTRO SCIENTIFIC INDS COM 285229100 1,539 51,378 SH   SOLE   51,378 0 0
ELECTRONIC ARTS INC COM 285512109 11,075 140,351 SH   SOLE   140,351 0 0
EMERSON ELEC CO COM 291011104 19,991 334,597 SH   SOLE   334,597 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 4,391 62,000 SH   SOLE   62,000 0 0
ENBRIDGE INC COM 29250N105 2,664 85,779 SH   SOLE   85,779 0 0
ENCANA CORP COM 292505104 1,283 222,429 SH   SOLE   222,429 0 0
ENDEAVOUR SILVER CORP COM 29258Y103 107 50,000 SH   SOLE   50,000 0 0
ENDOLOGIX INC COM 29266S106 100 140,000 SH   SOLE   140,000 0 0
ENERGIZER HLDGS INC NEW COM 29272W109 406 9,000 SH   SOLE   9,000 0 0
ENGILITY HLDGS INC NEW COM 29286C107 1,983 69,669 SH   SOLE   69,669 0 0
ENI S P A SPONSORED ADR 26874R108 1 31 SH   OTR 1 0 0 31
ENTERGY CORP NEW COM 29364G103 2,631 30,573 SH   SOLE   30,573 0 0
EOG RES INC COM 26875P101 4,546 52,132 SH   SOLE   52,132 0 0
EPR PPTYS COM SH BEN INT 26884U109 448 7,000 SH   SOLE   7,000 0 0
EQT CORP COM 26884L109 2,255 119,373 SH   SOLE   119,373 0 0
EQUIFAX INC COM 294429105 1,005 10,791 SH   SOLE   10,791 0 0
EQUINIX INC COM PAR $0.001 29444U700 2,110 5,986 SH   SOLE   5,986 0 0
EQUITRANS MIDSTREAM CORPORAT COM 294600101 801 40,020 SH   SOLE   40,020 0 0
EQUITY RESIDENTIAL SH BEN INT 29476L107 2,944 44,608 SH   SOLE   44,608 0 0
ESSEX PPTY TR INC COM 297178105 1,530 6,238 SH   SOLE   6,238 0 0
ETF MANAGERS TR PRIME CYBR SCRTY 26924G201 768 22,800 SH   SOLE   22,800 0 0
EVERSOURCE ENERGY COM 30040W108 1 11 SH   OTR 1 0 0 11
EVERSOURCE ENERGY COM 30040W108 3,334 51,259 SH   SOLE   51,259 0 0
EXACT SCIENCES CORP COM 30063P105 301 4,765 SH   SOLE   4,765 0 0
EXELIXIS INC COM 30161Q104 10,778 547,960 SH   SOLE   547,960 0 0
EXELON CORP COM 30161N101 4,881 108,234 SH   SOLE   108,234 0 0
EXPEDIA GROUP INC COM NEW 30212P303 823 7,304 SH   SOLE   7,304 0 0
EXPEDITORS INTL WASH INC COM 302130109 890 13,075 SH   SOLE   13,075 0 0
EXTRA SPACE STORAGE INC COM 30225T102 1,164 12,864 SH   SOLE   12,864 0 0
EXXON MOBIL CORP COM 30231G102 5 78 SH   OTR 1 0 0 78
EXXON MOBIL CORP COM 30231G102 46,599 683,394 SH   SOLE   683,394 0 0
F M C CORP COM NEW 302491303 599 8,098 SH   SOLE   8,098 0 0
F5 NETWORKS INC COM 315616102 8,879 54,802 SH   SOLE   54,802 0 0
FACEBOOK INC CL A 30303M102 60,603 462,324 SH   SOLE   462,324 0 0
FACTSET RESH SYS INC COM 303075105 400 2,000 SH   SOLE   2,000 0 0
FASTENAL CO COM 311900104 10,389 198,687 SH   SOLE   198,687 0 0
FEDERAL REALTY INVT TR SH BEN INT NEW 313747206 1,109 9,393 SH   SOLE   9,393 0 0
FEDEX CORP COM 31428X106 3,531 21,886 SH   SOLE   21,886 0 0
FIBROGEN INC COM 31572Q808 16,239 350,900 SH   SOLE   350,900 0 0
FIDELITY NATIONAL FINANCIAL FNF GROUP COM 31620R303 637 20,251 SH   SOLE   20,251 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 10,445 101,855 SH   SOLE   101,855 0 0
FIDELITY SOUTHERN CORP NEW COM 316394105 1,278 49,132 SH   SOLE   49,132 0 0
FIFTH THIRD BANCORP COM 316773100 9,360 397,801 SH   SOLE   397,801 0 0
FIREEYE INC COM 31816Q101 365 22,500 SH   SOLE   22,500 0 0
FIRST AMERN FINL CORP COM 31847R102 446 10,000 SH   SOLE   10,000 0 0
FIRST DATA CORP NEW COM CL A 32008D106 465 27,477 SH   SOLE   27,477 0 0
FIRST REP BK SAN FRANCISCO C COM 33616C100 1,632 18,782 SH   SOLE   18,782 0 0
FISERV INC COM 337738108 2,280 31,028 SH   SOLE   31,028 0 0
FLEETCOR TECHNOLOGIES INC COM 339041105 915 4,929 SH   SOLE   4,929 0 0
FLIR SYS INC COM 302445101 7,597 174,493 SH   SOLE   174,493 0 0
FLUOR CORP NEW COM 343412102 644 20,001 SH   SOLE   20,001 0 0
FOOT LOCKER INC COM 344849104 3,315 62,313 SH   SOLE   62,313 0 0
FORD MTR CO DEL COM PAR $0.01 345370860 2 289 SH   OTR 1 0 0 289
FORD MTR CO DEL COM PAR $0.01 345370860 3,055 399,333 SH   SOLE   399,333 0 0
FORTIVE CORP COM 34959J108 2,184 32,287 SH   SOLE   32,287 0 0
FORTUNE BRANDS HOME & SEC IN COM 34964C106 331 8,714 SH   SOLE   8,714 0 0
FORTY SEVEN INC COM 34983P104 314 20,000 SH   SOLE   20,000 0 0
FRANCO NEVADA CORP COM 351858105 271 3,870 SH   SOLE   3,870 0 0
FRANKLIN RES INC COM 354613101 14,481 488,256 SH   SOLE   488,256 0 0
GAP INC DEL COM 364760108 7,802 302,895 SH   SOLE   302,895 0 0
GARTNER INC COM 366651107 2,548 19,929 SH   SOLE   19,929 0 0
GENERAL ELECTRIC CO COM 369604103 1 122 SH   OTR 1 0 0 122
GENERAL ELECTRIC CO COM 369604103 16,519 2,182,258 SH   SOLE   2,182,258 0 0
GENERAL MLS INC COM 370334104 6,756 173,506 SH   SOLE   173,506 0 0
GENERAL MTRS CO COM 37045V100 7,594 227,022 SH   SOLE   227,022 0 0
GENOMIC HEALTH INC COM 37244C101 1,143 17,749 SH   SOLE   17,749 0 0
GENUINE PARTS CO COM 372460105 1,366 14,228 SH   SOLE   14,228 0 0
GILDAN ACTIVEWEAR INC COM 375916103 518 17,083 SH   SOLE   17,083 0 0
GILEAD SCIENCES INC COM 375558103 1 15 SH   OTR 1 0 0 15
GILEAD SCIENCES INC COM 375558103 98,443 1,573,898 SH   SOLE   1,573,898 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 3,941 96,000 SH   SOLE   96,000 0 0
GLOBAL PMTS INC COM 37940X102 1,352 13,114 SH   SOLE   13,114 0 0
GODADDY INC CL A 380237107 2,801 42,693 SH   SOLE   42,693 0 0
GOLD FIELDS LTD NEW SPONSORED ADR 38059T106 78 22,122 SH   SOLE   22,122 0 0
GOLD RESOURCE CORP COM 38068T105 40 10,000 SH   SOLE   10,000 0 0
GOLDCORP INC NEW COM 380956409 4,646 474,513 SH   SOLE   474,513 0 0
GOLDMAN SACHS GROUP INC COM 38141G104 7,468 44,706 SH   SOLE   44,706 0 0
GRACO INC COM 384109104 8,585 205,154 SH   SOLE   205,154 0 0
GRAINGER W W INC COM 384802104 2,787 9,872 SH   SOLE   9,872 0 0
GROUPE CGI INC CL A SUB VTG 39945C109 373 6,102 SH   SOLE   6,102 0 0
GRUPO FINANCIERO GALICIA S A SP ADR 10 SH B 399909100 5,762 209,000 SH   SOLE   209,000 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 4,012 41,200 SH   SOLE   41,200 0 0
HALLIBURTON CO COM 406216101 3,429 129,029 SH   SOLE   129,029 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 4,052 277,000 SH   SOLE   277,000 0 0
HARLEY DAVIDSON INC COM 412822108 2,502 73,343 SH   SOLE   73,343 0 0
HARTFORD FINL SVCS GROUP INC COM 416515104 8,341 187,654 SH   SOLE   187,654 0 0
HAWAIIAN ELEC INDUSTRIES COM 419870100 203 5,544 SH   SOLE   5,544 0 0
HCA HEALTHCARE INC COM 40412C101 21,522 172,946 SH   SOLE   172,946 0 0
HCP INC COM 40414L109 1,142 40,900 SH   SOLE   40,900 0 0
HD SUPPLY HLDGS INC COM 40416M105 808 21,526 SH   SOLE   21,526 0 0
HELEN OF TROY CORP LTD COM G4388N106 525 4,000 SH   SOLE   4,000 0 0
HENRY JACK & ASSOC INC COM 426281101 1 8 SH   OTR 1 0 0 8
HERON THERAPEUTICS INC COM 427746102 12,025 463,600 SH   SOLE   463,600 0 0
HERSHEY CO COM 427866108 2 18 SH   OTR 1 0 0 18
HERSHEY CO COM 427866108 2,434 22,713 SH   SOLE   22,713 0 0
HESS CORP COM 42809H107 9,045 223,350 SH   SOLE   223,350 0 0
HEWLETT PACKARD ENTERPRISE C COM 42824C109 3,526 266,902 SH   SOLE   266,902 0 0
HILTON WORLDWIDE HLDGS INC COM 43300A203 1 20 SH   OTR 1 0 0 20
HILTON WORLDWIDE HLDGS INC COM 43300A203 1,391 19,370 SH   SOLE   19,370 0 0
HOLLYFRONTIER CORP COM 436106108 2,823 55,228 SH   SOLE   55,228 0 0
HOLLYSYS AUTOMATION TECHNOLO SHS G45667105 7,907 451,599 SH   SOLE   451,599 0 0
HOLOGIC INC COM 436440101 504 12,260 SH   SOLE   12,260 0 0
HOME DEPOT INC COM 437076102 3 19 SH   OTR 1 0 0 19
HOME DEPOT INC COM 437076102 51,866 301,878 SH   SOLE   301,878 0 0
HONDA MOTOR LTD AMERN SHS 438128308 2 92 SH   OTR 1 0 0 92
HONEYWELL INTL INC COM 438516106 10,397 78,695 SH   SOLE   78,695 0 0
HORMEL FOODS CORP COM 440452100 1,132 26,528 SH   SOLE   26,528 0 0
HOST HOTELS & RESORTS INC COM 44107P104 1 66 SH   OTR 1 0 0 66
HOST HOTELS & RESORTS INC COM 44107P104 2,702 162,113 SH   SOLE   162,113 0 0
HP INC COM 40434L105 1 47 SH   OTR 1 0 0 47
HP INC COM 40434L105 4,312 210,765 SH   SOLE   210,765 0 0
HSBC HLDGS PLC SPON ADR NEW 404280406 1 34 SH   OTR 1 0 0 34
HUBBELL INC COM 443510607 3,893 39,192 SH   SOLE   39,192 0 0
HUMANA INC COM 444859102 9,194 32,095 SH   SOLE   32,095 0 0
HUNTINGTON BANCSHARES INC COM 446150104 2,503 209,974 SH   SOLE   209,974 0 0
IAC INTERACTIVECORP COM 44919P508 6,851 37,430 SH   SOLE   37,430 0 0
ICICI BK LTD ADR 45104G104 198 19,250 SH   SOLE   19,250 0 0
IDERA PHARMACEUTICALS INC COM PAR 45168K405 803 290,000 SH   SOLE   290,000 0 0
IDEX CORP COM 45167R104 1,391 11,018 SH   SOLE   11,018 0 0
IDEXX LABS INC COM 45168D104 1,102 5,924 SH   SOLE   5,924 0 0
IHS MARKIT LTD SHS G47567105 2,159 44,999 SH   SOLE   44,999 0 0
ILLINOIS TOOL WKS INC COM 452308109 9,204 72,654 SH   SOLE   72,654 0 0
ILLUMINA INC COM 452327109 69,314 231,110 SH   SOLE   231,110 0 0
IMMUNOGEN INC COM 45253H101 4,901 1,021,139 SH   SOLE   1,021,139 0 0
IMMUNOMEDICS INC COM 452907108 12,791 896,376 SH   SOLE   896,376 0 0
IMPERIAL OIL LTD COM NEW 453038408 460 18,170 SH   SOLE   18,170 0 0
IMPERVA INC COM 45321L100 2,311 41,500 SH   SOLE   41,500 0 0
INCYTE CORP COM 45337C102 29,601 465,522 SH   SOLE   465,522 0 0
INDIA FD INC COM 454089103 1,214 60,000 SH   SOLE   60,000 0 0
INFOSYS LTD SPONSORED ADR 456788108 1,843 193,606 SH   SOLE   193,606 0 0
INFRAREIT INC COM 45685L100 2,123 101,000 SH   SOLE   101,000 0 0
INGREDION INC COM 457187102 366 4,000 SH   SOLE   4,000 0 0
INSMED INC COM PAR $.01 457669307 926 70,567 SH   SOLE   70,567 0 0
INTEGRATED DEVICE TECHNOLOGY COM 458118106 6,840 141,237 SH   SOLE   141,237 0 0
INTEL CORP COM 458140100 1 23 SH   OTR 1 0 0 23
INTEL CORP COM 458140100 38,799 826,787 SH   SOLE   826,787 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 1,638 120,000 SH   SOLE   120,000 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 4,095 54,369 SH   SOLE   54,369 0 0
INTERNATIONAL BUSINESS MACHS COM 459200101 1 10 SH   OTR 1 0 0 10
INTERNATIONAL BUSINESS MACHS COM 459200101 24,678 217,118 SH   SOLE   217,118 0 0
INTERNATIONAL FLAVORS&FRAGRA COM 459506101 2,890 21,526 SH   SOLE   21,526 0 0
INTERPUBLIC GROUP COS INC COM 460690100 817 39,620 SH   SOLE   39,620 0 0
INTERSECT ENT INC COM 46071F103 845 30,000 SH   SOLE   30,000 0 0
INTL PAPER CO COM 460146103 2,790 69,127 SH   SOLE   69,127 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 7,267 638,000 SH   SOLE   638,000 0 0
INTUIT COM 461202103 17,323 88,006 SH   SOLE   88,006 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 22,003 45,946 SH   SOLE   45,946 0 0
INVESCO EXCHANGE TRADED FD T NASDAQ INTERNT 46137V530 302 2,750 SH   SOLE   2,750 0 0
INVESCO INDIA EXCHG TRED FD INDIA ETF 46137R109 2,087 86,333 SH   SOLE   86,333 0 0
INVESCO LTD SHS G491BT108 744 44,461 SH   SOLE   44,461 0 0
IONIS PHARMACEUTICALS INC COM 462222100 13,471 249,200 SH   SOLE   249,200 0 0
IPG PHOTONICS CORP COM 44980X109 3,161 27,907 SH   SOLE   27,907 0 0
IQVIA HLDGS INC COM 46266C105 2,168 18,660 SH   SOLE   18,660 0 0
ISHARES INC MSCI CDA ETF 464286509 5,488 229,070 SH   SOLE   229,070 0 0
ISHARES TR MSCI EMG MKT ETF 464287234 277 7,082 SH   SOLE   7,082 0 0
ISHARES TR MSCI INDIA ETF 46429B598 2,834 85,000 SH   SOLE   85,000 0 0
ISHARES TR U.S. REAL ES ETF 464287739 6,327 84,437 SH   SOLE   84,437 0 0
ISIS PHARMACEUTICALS INC DEL NOTE 1.000%11/1 464337AJ3 1,078 1,000 PRN   SOLE   1,000 0 0
ITAU UNIBANCO HLDG SA SPON ADR REP PFD 465562106 13,176 1,441,690 SH   SOLE   1,441,690 0 0
JACK IN THE BOX INC COM 466367109 388 5,000 SH   SOLE   5,000 0 0
JAZZ INVESTMENTS I LTD NOTE 1.875% 8/1 472145AB7 4,111 4,200 PRN   SOLE   4,200 0 0
JD COM INC SPON ADR CL A 47215P106 1,425 68,100 SH   SOLE   68,100 0 0
JEFFERIES FINL GROUP INC COM 47233W109 5,934 341,856 SH   SOLE   341,856 0 0
JOHNSON & JOHNSON COM 478160104 48,713 377,492 SH   SOLE   377,492 0 0
JOHNSON & JOHNSON COM 478160104 4 32 SH   OTR 1 0 0 32
JPMORGAN CHASE & CO COM 46625H100 49,852 510,696 SH   SOLE   510,696 0 0
JUNIPER NETWORKS INC COM 48203R104 3,619 134,491 SH   SOLE   134,491 0 0
KANSAS CITY SOUTHERN COM NEW 485170302 1,425 14,925 SH   SOLE   14,925 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 16,795 1,792,544 SH   SOLE   1,792,544 0 0
KB FINANCIAL GROUP INC SPONSORED ADR 48241A105 724 17,248 SH   SOLE   17,248 0 0
KELLOGG CO COM 487836108 5,872 103,009 SH   SOLE   103,009 0 0
KEYCORP NEW COM 493267108 3,123 211,326 SH   SOLE   211,326 0 0
KIMBERLY CLARK CORP COM 494368103 4,246 37,267 SH   SOLE   37,267 0 0
KIMCO RLTY CORP COM 49446R109 862 58,828 SH   SOLE   58,828 0 0
KINDER MORGAN INC DEL COM 49456B101 7,870 511,732 SH   SOLE   511,732 0 0
KINROSS GOLD CORP COM NO PAR 496902404 1,214 376,832 SH   SOLE   376,832 0 0
KIRKLAND LAKE GOLD LTD COM 49741E100 1,223 46,935 SH   SOLE   46,935 0 0
KLA-TENCOR CORP COM 482480100 1,278 14,282 SH   SOLE   14,282 0 0
KOHLS CORP COM 500255104 905 13,637 SH   SOLE   13,637 0 0
KRAFT HEINZ CO COM 500754106 2,906 67,513 SH   SOLE   67,513 0 0
KROGER CO COM 501044101 2,335 84,898 SH   SOLE   84,898 0 0
KT CORP SPONSORED ADR 48268K101 284 19,965 SH   SOLE   19,965 0 0
KURA ONCOLOGY INC COM 50127T109 5,138 366,000 SH   SOLE   366,000 0 0
L BRANDS INC COM 501797104 7,116 277,204 SH   SOLE   277,204 0 0
LA JOLLA PHARMACEUTICAL CO COM PAR $.0001 2 503459604 3,699 392,300 SH   SOLE   392,300 0 0
LABORATORY CORP AMER HLDGS COM NEW 50540R409 3,026 23,949 SH   SOLE   23,949 0 0
LAM RESEARCH CORP COM 512807108 1,313 9,646 SH   SOLE   9,646 0 0
LAMB WESTON HLDGS INC COM 513272104 1,265 17,201 SH   SOLE   17,201 0 0
LAS VEGAS SANDS CORP COM 517834107 1,358 26,093 SH   SOLE   26,093 0 0
LATAM AIRLS GROUP S A SPONSORED ADR 51817R106 174 16,880 SH   SOLE   16,880 0 0
LAUDER ESTEE COS INC CL A 518439104 24,201 186,023 SH   SOLE   186,023 0 0
LEAR CORP COM NEW 521865204 5,161 42,011 SH   SOLE   42,011 0 0
LEGGETT & PLATT INC COM 524660107 1,343 37,465 SH   SOLE   37,465 0 0
LENNAR CORP CL A 526057104 876 22,364 SH   SOLE   22,364 0 0
LENNOX INTL INC COM 526107107 896 4,095 SH   SOLE   4,095 0 0
LEXICON PHARMACEUTICALS INC COM NEW 528872302 3,380 509,000 SH   SOLE   509,000 0 0
LIBERTY MEDIA CORP DELAWARE COM C SIRIUSXM 531229607 636 17,209 SH   SOLE   17,209 0 0
LIFE STORAGE INC COM 53223X107 465 5,000 SH   SOLE   5,000 0 0
LIGAND PHARMACEUTICALS INC COM NEW 53220K504 2,035 15,000 SH   SOLE   15,000 0 0
LILLY ELI & CO COM 532457108 17,091 147,702 SH   SOLE   147,702 0 0
LINCOLN ELEC HLDGS INC COM 533900106 7,473 94,778 SH   SOLE   94,778 0 0
LINCOLN NATL CORP IND COM 534187109 5,927 115,519 SH   SOLE   115,519 0 0
LOEWS CORP COM 540424108 1,953 42,914 SH   SOLE   42,914 0 0
LOWES COS INC COM 548661107 11,346 122,849 SH   SOLE   122,849 0 0
LOXO ONCOLOGY INC COM 548862101 28,107 200,673 SH   SOLE   200,673 0 0
LULULEMON ATHLETICA INC COM 550021109 2,469 20,300 SH   SOLE   20,300 0 0
LUMENTUM HLDGS INC NOTE 0.250% 3/1 55024UAB5 2,003 2,000 PRN   SOLE   2,000 0 0
M & T BK CORP COM 55261F104 2,155 15,055 SH   SOLE   15,055 0 0
MACQUARIE INFRASTRUCTURE COR NOTE 2.875% 7/1 55608BAA3 6,031 6,000 PRN   SOLE   6,000 0 0
MACROGENICS INC COM 556099109 6,896 542,987 SH   SOLE   542,987 0 0
MACYS INC COM 55616P104 885 29,729 SH   SOLE   29,729 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 3,545 31,450 SH   SOLE   31,450 0 0
MAGNA INTL INC COM 559222401 1,258 27,718 SH   SOLE   27,718 0 0
MANPOWERGROUP INC COM 56418H100 449 6,936 SH   SOLE   6,936 0 0
MANULIFE FINL CORP COM 56501R106 1,906 134,389 SH   SOLE   134,389 0 0
MARATHON OIL CORP COM 565849106 4,697 327,570 SH   SOLE   327,570 0 0
MARATHON PETE CORP COM 56585A102 6,623 112,236 SH   SOLE   112,236 0 0
MARKEL CORP COM 570535104 1,310 1,262 SH   SOLE   1,262 0 0
MARRIOTT INTL INC NEW CL A 571903202 3,836 35,338 SH   SOLE   35,338 0 0
MARSH & MCLENNAN COS INC COM 571748102 1 13 SH   OTR 1 0 0 13
MARSH & MCLENNAN COS INC COM 571748102 5,385 67,523 SH   SOLE   67,523 0 0
MARTIN MARIETTA MATLS INC COM 573284106 5,620 32,702 SH   SOLE   32,702 0 0
MARVELL TECHNOLOGY GROUP LTD ORD G5876H105 891 55,044 SH   SOLE   55,044 0 0
MASCO CORP COM 574599106 1 44 SH   OTR 1 0 0 44
MASCO CORP COM 574599106 3,786 129,491 SH   SOLE   129,491 0 0
MASTERCARD INCORPORATED CL A 57636Q104 30,263 160,427 SH   SOLE   160,427 0 0
MATTEL INC COM 577081102 456 45,661 SH   SOLE   45,661 0 0
MAXIM INTEGRATED PRODS INC COM 57772K101 201 3,952 SH   SOLE   3,952 0 0
MAXIMUS INC COM 577933104 391 6,000 SH   SOLE   6,000 0 0
MCCORMICK & CO INC COM NON VTG 579780206 29,130 209,216 SH   SOLE   209,216 0 0
MCDONALDS CORP COM 580135101 13,124 73,915 SH   SOLE   73,915 0 0
MCKESSON CORP COM 58155Q103 1,753 15,867 SH   SOLE   15,867 0 0
MEDICAL PPTYS TRUST INC COM 58463J304 418 26,000 SH   SOLE   26,000 0 0
MEDICINES CO COM 584688105 2,612 136,500 SH   SOLE   136,500 0 0
MEDTRONIC PLC SHS G5960L103 1 13 SH   OTR 1 0 0 13
MEI PHARMA INC COM NEW 55279B202 1,346 510,000 SH   SOLE   510,000 0 0
MERCADOLIBRE INC COM 58733R102 6,136 20,953 SH   SOLE   20,953 0 0
MERCK & CO INC COM 58933Y105 76,411 1,000,057 SH   SOLE   1,000,057 0 0
MERCURY GENL CORP NEW COM 589400100 414 8,000 SH   SOLE   8,000 0 0
MESA LABS INC COM 59064R109 1,547 7,425 SH   SOLE   7,425 0 0
METHANEX CORP COM 59151K108 1,590 33,072 SH   SOLE   33,072 0 0
METLIFE INC COM 59156R108 1 28 SH   OTR 1 0 0 28
METLIFE INC COM 59156R108 16,912 411,901 SH   SOLE   411,901 0 0
METTLER TOLEDO INTERNATIONAL COM 592688105 2,162 3,822 SH   SOLE   3,822 0 0
MGM RESORTS INTERNATIONAL COM 552953101 1,430 58,951 SH   SOLE   58,951 0 0
MICHAEL KORS HLDGS LTD SHS G60754101 631 16,632 SH   SOLE   16,632 0 0
MICROCHIP TECHNOLOGY INC COM 595017104 5,785 80,447 SH   SOLE   80,447 0 0
MICROCHIP TECHNOLOGY INC NOTE 1.625% 2/1 595017AF1 3,085 3,160 PRN   SOLE   3,160 0 0
MICROCHIP TECHNOLOGY INC NOTE 2.250% 2/1 595017AH7 492 500 PRN   SOLE   500 0 0
MICRON TECHNOLOGY INC COM 595112103 1 23 SH   OTR 1 0 0 23
MICRON TECHNOLOGY INC COM 595112103 6,531 205,831 SH   SOLE   205,831 0 0
MICRON TECHNOLOGY INC NOTE 3.000%11/1 595112AY9 1,660 1,500 PRN   SOLE   1,500 0 0
MICROSOFT CORP COM 594918104 5 48 SH   OTR 1 0 0 48
MICROSOFT CORP COM 594918104 159,987 1,575,215 SH   SOLE   1,575,215 0 0
MIRATI THERAPEUTICS INC COM 60468T105 8,950 211,000 SH   SOLE   211,000 0 0
MOHAWK INDS INC COM 608190104 884 7,562 SH   SOLE   7,562 0 0
MOLSON COORS BREWING CO CL B 60871R209 12,087 215,226 SH   SOLE   215,226 0 0
MONDELEZ INTL INC CL A 609207105 6,527 163,058 SH   SOLE   163,058 0 0
MONDELEZ INTL INC CL A 609207105 2 50 SH   OTR 1 0 0 50
MONSTER BEVERAGE CORP NEW COM 61174X109 13,228 268,771 SH   SOLE   268,771 0 0
MOODYS CORP COM 615369105 2,090 14,924 SH   SOLE   14,924 0 0
MORGAN STANLEY COM NEW 617446448 11,710 295,353 SH   SOLE   295,353 0 0
MOSAIC CO NEW COM 61945C103 715 24,484 SH   SOLE   24,484 0 0
MOTOROLA SOLUTIONS INC COM NEW 620076307 3,888 33,798 SH   SOLE   33,798 0 0
MSCI INC COM 55354G100 876 5,944 SH   SOLE   5,944 0 0
MYOKARDIA INC COM 62857M105 2,980 61,000 SH   SOLE   61,000 0 0
NANTKWEST INC COM 63016Q102 270 232,400 SH   SOLE   232,400 0 0
NATIONAL FUEL GAS CO N J COM 636180101 2,135 41,724 SH   SOLE   41,724 0 0
NATIONAL GRID PLC SPONSORED ADR NE 636274409 1 19 SH   OTR 1 0 0 19
NATIONAL INSTRS CORP COM 636518102 3,608 79,501 SH   SOLE   79,501 0 0
NATIONAL OILWELL VARCO INC COM 637071101 1,224 47,623 SH   SOLE   47,623 0 0
NAVIGATORS GROUP INC COM 638904102 11,292 162,500 SH   SOLE   162,500 0 0
NEKTAR THERAPEUTICS COM 640268108 14,666 446,206 SH   SOLE   446,206 0 0
NETAPP INC COM 64110D104 1,968 32,982 SH   SOLE   32,982 0 0
NETFLIX INC COM 64110L106 11,151 41,662 SH   SOLE   41,662 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 16,286 228,069 SH   SOLE   228,069 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1 236 200 PRN   SOLE   200 0 0
NEVSUN RES LTD COM 64156L101 2,356 537,300 SH   SOLE   537,300 0 0
NEW ORIENTAL ED & TECH GRP I SPON ADR 647581107 1,206 22,000 SH   SOLE   22,000 0 0
NEWELL BRANDS INC COM 651229106 655 35,212 SH   SOLE   35,212 0 0
NEWFIELD EXPL CO COM 651290108 1,132 77,219 SH   SOLE   77,219 0 0
NEWMONT MINING CORP COM 651639106 8,360 241,271 SH   SOLE   241,271 0 0
NEXEO SOLUTIONS INC COM SHS 65342H102 1,003 116,732 SH   SOLE   116,732 0 0
NEXTERA ENERGY INC COM 65339F101 9,432 54,265 SH   SOLE   54,265 0 0
NIKE INC CL B 654106103 10,756 145,079 SH   SOLE   145,079 0 0
NOBLE ENERGY INC COM 655044105 3,098 165,125 SH   SOLE   165,125 0 0
NORDSTROM INC COM 655664100 1,470 31,544 SH   SOLE   31,544 0 0
NORFOLK SOUTHERN CORP COM 655844108 1 8 SH   OTR 1 0 0 8
NORFOLK SOUTHERN CORP COM 655844108 3,922 26,229 SH   SOLE   26,229 0 0
NORTHERN TR CORP COM 665859104 2,439 29,176 SH   SOLE   29,176 0 0
NORWEGIAN CRUISE LINE HLDG L SHS G66721104 496 11,709 SH   SOLE   11,709 0 0
NUANCE COMMUNICATIONS INC DBCV 1.000%12/1 67020YAK6 3,035 3,500 PRN   SOLE   3,500 0 0
NUCOR CORP COM 670346105 2,549 49,210 SH   SOLE   49,210 0 0
NUTRI SYS INC NEW COM 67069D108 2,214 50,466 SH   SOLE   50,466 0 0
NUTRIEN LTD COM 67077M108 11,619 247,495 SH   SOLE   247,495 0 0
NVIDIA CORP COM 67066G104 18,069 135,358 SH   SOLE   135,358 0 0
NVR INC COM 62944T105 9,531 3,911 SH   SOLE   3,911 0 0
NXP SEMICONDUCTORS N V NOTE 1.000%12/0 62952QAB6 5,216 5,200 PRN   SOLE   5,200 0 0
NXSTAGE MEDICAL INC COM 67072V103 2,657 92,842 SH   SOLE   92,842 0 0
O REILLY AUTOMOTIVE INC NEW COM 67103H107 1,870 5,431 SH   SOLE   5,431 0 0
OCCIDENTAL PETE CORP DEL COM 674599105 5,610 91,399 SH   SOLE   91,399 0 0
OMEGA HEALTHCARE INVS INC COM 681936100 457 13,000 SH   SOLE   13,000 0 0
OMNICOM GROUP INC COM 681919106 1 12 SH   OTR 1 0 0 12
OMNICOM GROUP INC COM 681919106 6,057 82,705 SH   SOLE   82,705 0 0
ON SEMICONDUCTOR CORP NOTE 1.000%12/0 682189AK1 1,104 1,000 PRN   SOLE   1,000 0 0
ON SEMICONDUCTOR CORP NOTE 1.625%10/1 682189AP0 1,075 1,000 PRN   SOLE   1,000 0 0
ONCOMED PHARMACEUTICALS INC COM 68234X102 284 380,000 SH   SOLE   380,000 0 0
ONEOK INC NEW COM 682680103 4,379 81,170 SH   SOLE   81,170 0 0
ORACLE CORP COM 68389X105 1 20 SH   OTR 1 0 0 20
ORACLE CORP COM 68389X105 36,535 809,223 SH   SOLE   809,223 0 0
ORIX CORP SPONSORED ADR 686330101 0 6 SH   OTR 1 0 0 6
OSISKO GOLD ROYALTIES LTD COM 68827L101 908 103,632 SH   SOLE   103,632 0 0
OWENS CORNING NEW COM 690742101 655 14,902 SH   SOLE   14,902 0 0
PACCAR INC COM 693718108 15,932 278,838 SH   SOLE   278,838 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,126 287,355 SH   SOLE   287,355 0 0
PACKAGING CORP AMER COM 695156109 4,057 48,607 SH   SOLE   48,607 0 0
PALO ALTO NETWORKS INC COM 697435105 15,772 83,743 SH   SOLE   83,743 0 0
PAPA JOHNS INTL INC COM 698813102 358 9,000 SH   SOLE   9,000 0 0
PARKER HANNIFIN CORP COM 701094104 2,948 19,767 SH   SOLE   19,767 0 0
PATTERSON COMPANIES INC COM 703395103 374 19,000 SH   SOLE   19,000 0 0
PAYCHEX INC COM 704326107 1,670 25,632 SH   SOLE   25,632 0 0
PAYPAL HLDGS INC COM 70450Y103 40,304 479,321 SH   SOLE   479,321 0 0
PDC ENERGY INC NOTE 1.125% 9/1 69327RAD3 1,767 2,000 PRN   SOLE   2,000 0 0
PEMBINA PIPELINE CORP COM 706327103 1,647 55,540 SH   SOLE   55,540 0 0
PENN VA CORP NEW COM 70788V102 876 16,204 SH   SOLE   16,204 0 0
PENTAIR PLC SHS G7S00T104 2 45 SH   OTR 1 0 0 45
PEOPLES UNITED FINANCIAL INC COM 712704105 1 71 SH   OTR 1 0 0 71
PEOPLES UNITED FINANCIAL INC COM 712704105 751 52,029 SH   SOLE   52,029 0 0
PEPSICO INC COM 713448108 20,768 187,994 SH   SOLE   187,994 0 0
PEPSICO INC COM 713448108 3 25 SH   OTR 1 0 0 25
PERKINELMER INC COM 714046109 3,142 40,000 SH   SOLE   40,000 0 0
PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408 524 40,265 SH   SOLE   40,265 0 0
PFIZER INC COM 717081103 19,818 454,048 SH   SOLE   454,048 0 0
PG&E CORP COM 69331C108 5,495 231,396 SH   SOLE   231,396 0 0
PHILLIPS 66 COM 718546104 2 20 SH   OTR 1 0 0 20
PHILLIPS 66 COM 718546104 5,512 63,985 SH   SOLE   63,985 0 0
PIONEER NAT RES CO COM 723787107 3,666 27,878 SH   SOLE   27,878 0 0
PLAINS GP HLDGS L P LTD PARTNR INT A 72651A207 313 15,595 SH   SOLE   15,595 0 0
PNC FINL SVCS GROUP INC COM 693475105 4,399 37,628 SH   SOLE   37,628 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 3,207 164,300 SH   SOLE   164,300 0 0
POWER INTEGRATIONS INC COM 739276103 242 3,962 SH   SOLE   3,962 0 0
PPG INDS INC COM 693506107 2,369 23,178 SH   SOLE   23,178 0 0
PPL CORP COM 69351T106 425 15,000 SH   SOLE   15,000 0 0
PRICE T ROWE GROUP INC COM 74144T108 2,005 21,717 SH   SOLE   21,717 0 0
PRICELINE GRP INC NOTE 0.350% 6/1 741503AS5 2,690 2,000 PRN   SOLE   2,000 0 0
PRICELINE GRP INC NOTE 0.900% 9/1 741503AX4 844 761 PRN   SOLE   761 0 0
PRINCIPAL FINL GROUP INC COM 74251V102 1,980 44,821 SH   SOLE   44,821 0 0
PROCTER AND GAMBLE CO COM 742718109 3 30 SH   OTR 1 0 0 30
PROCTER AND GAMBLE CO COM 742718109 71,570 778,641 SH   SOLE   778,641 0 0
PROGRESSIVE CORP OHIO COM 743315103 4,658 77,212 SH   SOLE   77,212 0 0
PROLOGIS INC COM 74340W103 1 12 SH   OTR 1 0 0 12
PROLOGIS INC COM 74340W103 5,172 88,091 SH   SOLE   88,091 0 0
PROTEOSTASIS THERAPEUTICS IN COM 74373B109 810 250,000 SH   SOLE   250,000 0 0
PRUDENTIAL FINL INC COM 744320102 18,238 223,646 SH   SOLE   223,646 0 0
PRUDENTIAL FINL INC COM 744320102 2 19 SH   OTR 1 0 0 19
PTC INC COM 69370C100 19,443 234,542 SH   SOLE   234,542 0 0
PTC THERAPEUTICS INC COM 69366J200 13,814 402,523 SH   SOLE   402,523 0 0
PUBLIC STORAGE COM 74460D109 2,944 14,545 SH   SOLE   14,545 0 0
PUBLIC SVC ENTERPRISE GROUP COM 744573106 2,872 55,187 SH   SOLE   55,187 0 0
PULTE GROUP INC COM 745867101 3,919 150,799 SH   SOLE   150,799 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 7,035 345,737 SH   SOLE   345,737 0 0
PVH CORP COM 693656100 3,488 37,528 SH   SOLE   37,528 0 0
QORVO INC COM 74736K101 3,643 59,990 SH   SOLE   59,990 0 0
QUALCOMM INC COM 747525103 10,228 179,729 SH   SOLE   179,729 0 0
QUEST DIAGNOSTICS INC COM 74834L100 1 14 SH   OTR 1 0 0 14
QUEST DIAGNOSTICS INC COM 74834L100 1,853 22,259 SH   SOLE   22,259 0 0
QURATE RETAIL INC COM SER A 74915M100 750 38,407 SH   SOLE   38,407 0 0
RA PHARMACEUTICALS INC COM 74933V108 15,997 879,000 SH   SOLE   879,000 0 0
RADIUS HEALTH INC COM NEW 750469207 5,013 304,025 SH   SOLE   304,025 0 0
RALPH LAUREN CORP CL A 751212101 433 4,187 SH   SOLE   4,187 0 0
RAYMOND JAMES FINANCIAL INC COM 754730109 2,213 29,740 SH   SOLE   29,740 0 0
REALTY INCOME CORP COM 756109104 1,545 24,504 SH   SOLE   24,504 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 11,175 199,200 SH   SOLE   199,200 0 0
RED HAT INC COM 756577102 8,746 49,799 SH   SOLE   49,799 0 0
REDHILL BIOPHARMA LTD SPONSORED ADS 757468103 395 71,267 SH   SOLE   71,267 0 0
REGENCY CTRS CORP COM 758849103 1,090 18,583 SH   SOLE   18,583 0 0
REGENERON PHARMACEUTICALS COM 75886F107 130,478 349,354 SH   SOLE   349,354 0 0
REGIONS FINL CORP NEW COM 7591EP100 7,944 593,777 SH   SOLE   593,777 0 0
REINSURANCE GROUP AMER INC COM NEW 759351604 7,414 52,870 SH   SOLE   52,870 0 0
RELX PLC SPONSORED ADR 759530108 1 51 SH   OTR 1 0 0 51
REPUBLIC SVCS INC COM 760759100 2,721 37,745 SH   SOLE   37,745 0 0
REPUBLIC SVCS INC COM 760759100 2 30 SH   OTR 1 0 0 30
RESMED INC COM 761152107 4,164 36,570 SH   SOLE   36,570 0 0
RESTAURANT BRANDS INTL INC COM 76131D103 245 4,688 SH   SOLE   4,688 0 0
REVANCE THERAPEUTICS INC COM 761330109 4,771 237,000 SH   SOLE   237,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 5,699 2,478,000 SH   SOLE   2,478,000 0 0
ROBERT HALF INTL INC COM 770323103 944 16,498 SH   SOLE   16,498 0 0
ROCKWELL AUTOMATION INC COM 773903109 31,260 207,748 SH   SOLE   207,748 0 0
ROGERS COMMUNICATIONS INC CL B 775109200 1,818 35,484 SH   SOLE   35,484 0 0
ROLLINS INC COM 775711104 216 5,994 SH   SOLE   5,994 0 0
ROPER TECHNOLOGIES INC COM 776696106 4,452 16,705 SH   SOLE   16,705 0 0
ROSS STORES INC COM 778296103 2,153 25,879 SH   SOLE   25,879 0 0
ROVI CORP NOTE 0.500% 3/0 779376AD4 2,832 3,000 PRN   SOLE   3,000 0 0
ROYAL BK CDA MONTREAL QUE COM 780087102 8,818 128,902 SH   SOLE   128,902 0 0
RTI INTL METALS INC NOTE 1.625%10/1 74973WAB3 239 240 PRN   SOLE   240 0 0
S&P GLOBAL INC COM 78409V104 4,416 25,987 SH   SOLE   25,987 0 0
SAGE THERAPEUTICS INC COM 78667J108 15,354 160,300 SH   SOLE   160,300 0 0
SALESFORCE COM INC COM 79466L302 37,433 273,304 SH   SOLE   273,304 0 0
SANOFI SPONSORED ADR 80105N105 1 31 SH   OTR 1 0 0 31
SAREPTA THERAPEUTICS INC COM 803607100 13,761 126,100 SH   SOLE   126,100 0 0
SBA COMMUNICATIONS CORP NEW CL A 78410G104 2,640 16,311 SH   SOLE   16,311 0 0
SCHEIN HENRY INC COM 806407102 716 9,123 SH   SOLE   9,123 0 0
SCHLUMBERGER LTD COM 806857108 1 20 SH   OTR 1 0 0 20
SCHLUMBERGER LTD COM 806857108 14,158 392,438 SH   SOLE   392,438 0 0
SCHWAB CHARLES CORP NEW COM 808513105 4,264 102,683 SH   SOLE   102,683 0 0
SEATTLE GENETICS INC COM 812578102 8,010 141,374 SH   SOLE   141,374 0 0
SEI INVESTMENTS CO COM 784117103 1 23 SH   OTR 1 0 0 23
SEMPRA ENERGY COM 816851109 3,835 35,452 SH   SOLE   35,452 0 0
SENDGRID INC COM 816883102 6,873 159,219 SH   SOLE   159,219 0 0
SERVICE CORP INTL COM 817565104 11,465 284,813 SH   SOLE   284,813 0 0
SERVICENOW INC COM 81762P102 2,345 13,170 SH   SOLE   13,170 0 0
SHAW COMMUNICATIONS INC CL B CONV 82028K200 1,107 61,205 SH   SOLE   61,205 0 0
SHERWIN WILLIAMS CO COM 824348106 22,309 56,702 SH   SOLE   56,702 0 0
SHINHAN FINANCIAL GROUP CO L SPN ADR RESTRD 824596100 705 19,879 SH   SOLE   19,879 0 0
SHIRE PLC SPONSORED ADR 82481R106 8,301 47,698 SH   SOLE   47,698 0 0
SHOPIFY INC CL A 82509L107 287 2,074 SH   SOLE   2,074 0 0
SIERRA ONCOLOGY INC COM 82640U107 950 720,000 SH   SOLE   720,000 0 0
SILICON LABORATORIES INC COM 826919102 8,877 112,647 SH   SOLE   112,647 0 0
SIMON PPTY GROUP INC NEW COM 828806109 4,334 25,798 SH   SOLE   25,798 0 0
SIX FLAGS ENTMT CORP NEW COM 83001A102 2,794 50,234 SH   SOLE   50,234 0 0
SK TELECOM LTD SPONSORED ADR 78440P108 427 15,920 SH   SOLE   15,920 0 0
SKYWORKS SOLUTIONS INC COM 83088M102 667 9,953 SH   SOLE   9,953 0 0
SL GREEN RLTY CORP COM 78440X101 242 3,061 SH   SOLE   3,061 0 0
SMITH A O COM 831865209 303 7,086 SH   SOLE   7,086 0 0
SMUCKER J M CO COM NEW 832696405 1,214 12,987 SH   SOLE   12,987 0 0
SNAP ON INC COM 833034101 2,386 16,426 SH   SOLE   16,426 0 0
SONY CORP SPONSORED ADR 835699307 1 15 SH   OTR 1 0 0 15
SOUTHWEST AIRLS CO COM 844741108 9,033 194,343 SH   SOLE   194,343 0 0
SOUTHWEST GAS HOLDINGS INC COM 844895102 6,124 80,051 SH   SOLE   80,051 0 0
SPARK THERAPEUTICS INC COM 84652J103 2,313 59,100 SH   SOLE   59,100 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 621 133,500 SH Put SOLE   133,500 0 0
SPDR SERIES TRUST S&P BIOTECH 78464A870 301 4,195 SH   SOLE   4,195 0 0
SPECTRUM PHARMACEUTICALS INC COM 84763A108 8,573 979,825 SH   SOLE   979,825 0 0
SPIRIT AEROSYSTEMS HLDGS INC COM CL A 848574109 7,414 102,855 SH   SOLE   102,855 0 0
SPIRIT RLTY CAP INC NEW NOTE 2.875% 5/1 84860WAA0 2,004 2,000 PRN   SOLE   2,000 0 0
SPLUNK INC COM 848637104 13,443 128,222 SH   SOLE   128,222 0 0
SPRINT CORP COM SER 1 85207U105 1,272 218,600 SH   SOLE   218,600 0 0
SQUARE INC CL A 852234103 1,294 23,065 SH   SOLE   23,065 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 1,244 39,000 SH   SOLE   39,000 0 0
STANLEY BLACK & DECKER INC COM 854502101 4,367 36,469 SH   SOLE   36,469 0 0
STARBUCKS CORP COM 855244109 12,464 193,551 SH   SOLE   193,551 0 0
STATE STR CORP COM 857477103 1,965 31,163 SH   SOLE   31,163 0 0
STEEL DYNAMICS INC COM 858119100 806 26,819 SH   SOLE   26,819 0 0
STRYKER CORP COM 863667101 9,984 63,696 SH   SOLE   63,696 0 0
SUN LIFE FINL INC COM 866796105 1,659 50,028 SH   SOLE   50,028 0 0
SUNCOR ENERGY INC NEW COM 867224107 4,874 174,573 SH   SOLE   174,573 0 0
SUNTRUST BKS INC COM 867914103 7,477 148,238 SH   SOLE   148,238 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 4,485 135,000 SH   SOLE   135,000 0 0
SVB FINL GROUP COM 78486Q101 490 2,578 SH   SOLE   2,578 0 0
SYMANTEC CORP COM 871503108 1,415 74,878 SH   SOLE   74,878 0 0
SYNCHRONY FINL COM 87165B103 8,350 355,941 SH   SOLE   355,941 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 1,136 204,000 SH   SOLE   204,000 0 0
SYSCO CORP COM 871829107 1 16 SH   OTR 1 0 0 16
SYSCO CORP COM 871829107 3,767 60,119 SH   SOLE   60,119 0 0
T MOBILE US INC COM 872590104 2,977 46,797 SH   SOLE   46,797 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADR 874039100 21,617 585,686 SH   SOLE   585,686 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 641 6,223 SH   SOLE   6,223 0 0
TAL ED GROUP SPONSORED ADS 874080104 14,487 543,000 SH   SOLE   543,000 0 0
TANGER FACTORY OUTLET CTRS I COM 875465106 445 22,000 SH   SOLE   22,000 0 0
TAPESTRY INC COM 876030107 593 17,562 SH   SOLE   17,562 0 0
TARGA RES CORP COM 87612G101 949 26,343 SH   SOLE   26,343 0 0
TARGET CORP COM 87612E106 1 13 SH   OTR 1 0 0 13
TARGET CORP COM 87612E106 5,367 81,214 SH   SOLE   81,214 0 0
TD AMERITRADE HLDG CORP COM 87236Y108 927 18,935 SH   SOLE   18,935 0 0
TE CONNECTIVITY LTD REG SHS H84989104 2 28 SH   OTR 1 0 0 28
TECK RESOURCES LTD CL B 878742204 904 42,004 SH   SOLE   42,004 0 0
TELEFONICA S A SPONSORED ADR 879382208 2 258 SH   OTR 1 0 0 258
TELUS CORP COM 87971M103 4,466 134,800 SH   SOLE   134,800 0 0
TESARO INC COM 881569107 5,940 80,000 SH   SOLE   80,000 0 0
TESLA INC COM 88160R101 14,303 42,979 SH   SOLE   42,979 0 0
TETRAPHASE PHARMACEUTICALS I COM 88165N105 18 15,613 SH   SOLE   15,613 0 0
TEXAS INSTRS INC COM 882508104 1 10 SH   OTR 1 0 0 10
TEXAS INSTRS INC COM 882508104 13,575 143,659 SH   SOLE   143,659 0 0
TG THERAPEUTICS INC COM 88322Q108 2,837 692,000 SH   SOLE   692,000 0 0
THERAVANCE BIOPHARMA INC COM G8807B106 7,157 279,700 SH   SOLE   279,700 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 19,560 87,406 SH   SOLE   87,406 0 0
THOMSON REUTERS CORP COM NEW 884903709 722 14,953 SH   SOLE   14,953 0 0
TIFFANY & CO NEW COM 886547108 12,477 154,985 SH   SOLE   154,985 0 0
TJX COS INC NEW COM 872540109 1 23 SH   OTR 1 0 0 23
TJX COS INC NEW COM 872540109 16,921 378,228 SH   SOLE   378,228 0 0
TOLL BROTHERS INC COM 889478103 244 7,424 SH   SOLE   7,424 0 0
TORCHMARK CORP COM 891027104 2 31 SH   OTR 1 0 0 31
TORCHMARK CORP COM 891027104 1,127 15,116 SH   SOLE   15,116 0 0
TORONTO DOMINION BK ONT COM NEW 891160509 9,885 198,969 SH   SOLE   198,969 0 0
TOTAL S A SPONSORED ADR 89151E109 3 57 SH   OTR 1 0 0 57
TOYOTA MOTOR CORP SP ADR REP2COM 892331307 4 37 SH   OTR 1 0 0 37
TRACTOR SUPPLY CO COM 892356106 6,674 79,987 SH   SOLE   79,987 0 0
TRANSCANADA CORP COM 89353D107 4,663 130,634 SH   SOLE   130,634 0 0
TRANSDIGM GROUP INC COM 893641100 1,718 5,051 SH   SOLE   5,051 0 0
TRANSUNION COM 89400J107 690 12,153 SH   SOLE   12,153 0 0
TRAVELERS COMPANIES INC COM 89417E109 13,304 111,104 SH   SOLE   111,104 0 0
TREEHOUSE FOODS INC COM 89469A104 558 11,000 SH   SOLE   11,000 0 0
TRIBUNE MEDIA CO CL A 896047503 2,269 50,000 SH   SOLE   50,000 0 0
TRIMBLE INC COM 896239100 18,662 567,094 SH   SOLE   567,094 0 0
TRUSTMARK CORP COM 898402102 455 16,000 SH   SOLE   16,000 0 0
TWENTY FIRST CENTY FOX INC CL A 90130A101 5,102 106,033 SH   SOLE   106,033 0 0
TWENTY FIRST CENTY FOX INC CL B 90130A200 1,189 24,895 SH   SOLE   24,895 0 0
TWITTER INC COM 90184L102 1,411 49,112 SH   SOLE   49,112 0 0
TWITTER INC NOTE 0.250% 9/1 90184LAB8 6,806 7,000 PRN   SOLE   7,000 0 0
TYLER TECHNOLOGIES INC COM 902252105 2,623 14,115 SH   SOLE   14,115 0 0
U S G CORP COM NEW 903293405 4,266 100,000 SH   SOLE   100,000 0 0
UGI CORP NEW COM 902681105 3,353 62,861 SH   SOLE   62,861 0 0
ULTA BEAUTY INC COM 90384S303 828 3,382 SH   SOLE   3,382 0 0
ULTIMATE SOFTWARE GROUP INC COM 90385D107 2,991 12,216 SH   SOLE   12,216 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 5,022 115,500 SH   SOLE   115,500 0 0
UNDER ARMOUR INC CL A 904311107 341 19,277 SH   SOLE   19,277 0 0
UNION PAC CORP COM 907818108 19,496 141,047 SH   SOLE   141,047 0 0
UNION PAC CORP COM 907818108 1 8 SH   OTR 1 0 0 8
UNITED MICROELECTRONICS CORP SPON ADR NEW 910873405 406 226,796 SH   SOLE   226,796 0 0
UNITED PARCEL SERVICE INC CL B 911312106 19,508 200,025 SH   SOLE   200,025 0 0
UNITED RENTALS INC COM 911363109 673 6,568 SH   SOLE   6,568 0 0
UNITEDHEALTH GROUP INC COM 91324P102 52,885 212,298 SH   SOLE   212,298 0 0
UNIVERSAL DISPLAY CORP COM 91347P105 9,343 99,853 SH   SOLE   99,853 0 0
UNIVERSAL HLTH SVCS INC CL B 913903100 10,446 89,627 SH   SOLE   89,627 0 0
UNUM GROUP COM 91529Y106 8,061 274,372 SH   SOLE   274,372 0 0
URBAN OUTFITTERS INC COM 917047102 398 12,000 SH   SOLE   12,000 0 0
US BANCORP DEL COM NEW 902973304 1 21 SH   OTR 1 0 0 21
US BANCORP DEL COM NEW 902973304 6,617 144,798 SH   SOLE   144,798 0 0
V F CORP COM 918204108 5,746 80,542 SH   SOLE   80,542 0 0
VALE S A ADR 91912E105 453 34,335 SH   SOLE   34,335 0 0
VALERO ENERGY CORP NEW COM 91913Y100 1 13 SH   OTR 1 0 0 13
VALERO ENERGY CORP NEW COM 91913Y100 7,542 100,600 SH   SOLE   100,600 0 0
VANDA PHARMACEUTICALS INC COM 921659108 4,651 178,000 SH   SOLE   178,000 0 0
VARIAN MED SYS INC COM 92220P105 1,297 11,444 SH   SOLE   11,444 0 0
VARONIS SYS INC COM 922280102 9,436 178,374 SH   SOLE   178,374 0 0
VECTREN CORP COM 92240G101 2,267 31,500 SH   SOLE   31,500 0 0
VEECO INSTRS INC DEL COM 922417100 3,623 489,002 SH   SOLE   489,002 0 0
VEEVA SYS INC CL A COM 922475108 3,891 43,566 SH   SOLE   43,566 0 0
VENTAS INC COM 92276F100 1,673 28,563 SH   SOLE   28,563 0 0
VEREIT INC COM 92339V100 847 118,528 SH   SOLE   118,528 0 0
VERISIGN INC COM 92343E102 1 7 SH   OTR 1 0 0 7
VERISIGN INC COM 92343E102 1,675 11,295 SH   SOLE   11,295 0 0
VERISK ANALYTICS INC COM 92345Y106 1,487 13,639 SH   SOLE   13,639 0 0
VERIZON COMMUNICATIONS INC COM 92343V104 4 65 SH   OTR 1 0 0 65
VERIZON COMMUNICATIONS INC COM 92343V104 45,845 815,500 SH   SOLE   815,500 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 105,285 635,385 SH   SOLE   635,385 0 0
VIACOM INC NEW CL B 92553P201 6,169 240,034 SH   SOLE   240,034 0 0
VIEWRAY INC COM 92672L107 62 10,182 SH   SOLE   10,182 0 0
VISA INC COM CL A 92826C839 3 25 SH   OTR 1 0 0 25
VISA INC COM CL A 92826C839 63,178 478,863 SH   SOLE   478,863 0 0
VISTRA ENERGY CORP COM 92840M102 684 29,900 SH   SOLE   29,900 0 0
VMWARE INC CL A COM 928563402 14,470 105,523 SH   SOLE   105,523 0 0
VODAFONE GROUP PLC NEW SPONSORED ADR 92857W308 1 37 SH   OTR 1 0 0 37
VORNADO RLTY TR SH BEN INT 929042109 1,530 24,668 SH   SOLE   24,668 0 0
VOYA FINL INC COM 929089100 283 7,044 SH   SOLE   7,044 0 0
VULCAN MATLS CO COM 929160109 1,000 10,124 SH   SOLE   10,124 0 0
WABCO HLDGS INC COM 92927K102 722 6,728 SH   SOLE   6,728 0 0
WABTEC CORP COM 929740108 4,175 59,433 SH   SOLE   59,433 0 0
WALGREENS BOOTS ALLIANCE INC COM 931427108 1 14 SH   OTR 1 0 0 14
WALGREENS BOOTS ALLIANCE INC COM 931427108 6,511 95,293 SH   SOLE   95,293 0 0
WALMART INC COM 931142103 2,048 21,991 SH   SOLE   21,991 0 0
WASTE CONNECTIONS INC COM 94106B101 1,608 21,651 SH   SOLE   21,651 0 0
WASTE MGMT INC DEL COM 94106L109 2 24 SH   OTR 1 0 0 24
WASTE MGMT INC DEL COM 94106L109 9,143 102,747 SH   SOLE   102,747 0 0
WATERS CORP COM 941848103 2,059 10,917 SH   SOLE   10,917 0 0
WEIBO CORP SPONSORED ADR 948596101 876 15,000 SH   SOLE   15,000 0 0
WEINGARTEN RLTY INVS SH BEN INT 948741103 447 18,000 SH   SOLE   18,000 0 0
WELLCARE HEALTH PLANS INC COM 94946T106 1,013 4,292 SH   SOLE   4,292 0 0
WELLS FARGO CO NEW COM 949746101 3 66 SH   OTR 1 0 0 66
WELLS FARGO CO NEW COM 949746101 22,004 477,530 SH   SOLE   477,530 0 0
WELLTOWER INC COM 95040Q104 2,434 35,070 SH   SOLE   35,070 0 0
WESTERN DIGITAL CORP COM 958102105 3,844 103,994 SH   SOLE   103,994 0 0
WESTERN UN CO COM 959802109 824 48,328 SH   SOLE   48,328 0 0
WESTPAC BKG CORP SPONSORED ADR 961214301 1 54 SH   OTR 1 0 0 54
WESTROCK CO COM 96145D105 3,973 105,219 SH   SOLE   105,219 0 0
WEX INC COM 96208T104 2,518 17,980 SH   SOLE   17,980 0 0
WEYERHAEUSER CO COM 962166104 1,640 75,034 SH   SOLE   75,034 0 0
WHIRLPOOL CORP COM 963320106 488 4,563 SH   SOLE   4,563 0 0
WILDHORSE RESOURCE DEV CORP COM 96812T102 705 49,998 SH   SOLE   49,998 0 0
WILLIAMS COS INC DEL COM 969457100 8,005 363,041 SH   SOLE   363,041 0 0
WIPRO LTD SPON ADR 1 SH 97651M109 445 86,762 SH   SOLE   86,762 0 0
WORKDAY INC CL A 98138H101 1,402 8,782 SH   SOLE   8,782 0 0
WORKDAY INC NOTE 0.250%10/0 98138HAF8 1,980 1,600 PRN   SOLE   1,600 0 0
WORLD FUEL SVCS CORP COM 981475106 300 14,000 SH   SOLE   14,000 0 0
WORLDPAY INC CL A 981558109 1,333 17,442 SH   SOLE   17,442 0 0
WRIGHT MED GROUP INC NOTE 2.000% 2/1 98235TAE7 319 300 PRN   SOLE   300 0 0
WYNN RESORTS LTD COM 983134107 699 7,068 SH   SOLE   7,068 0 0
XEROX CORP COM NEW 984121608 360 18,213 SH   SOLE   18,213 0 0
XILINX INC COM 983919101 14,363 168,649 SH   SOLE   168,649 0 0
XPO LOGISTICS INC COM 983793100 458 8,038 SH   SOLE   8,038 0 0
XYLEM INC COM 98419M100 14,970 224,384 SH   SOLE   224,384 0 0
YUM BRANDS INC COM 988498101 1 12 SH   OTR 1 0 0 12
YUM BRANDS INC COM 988498101 2,518 27,391 SH   SOLE   27,391 0 0
ZAFGEN INC COM 98885E103 2,668 539,000 SH   SOLE   539,000 0 0
ZILLOW GROUP INC CL C CAP STK 98954M200 2,746 86,955 SH   SOLE   86,955 0 0
ZILLOW GROUP INC NOTE 2.000%12/0 98954MAB7 1,959 2,000 PRN   SOLE   2,000 0 0
ZIMMER BIOMET HLDGS INC COM 98956P102 10,003 96,446 SH   SOLE   96,446 0 0
ZIONS BANCORPORATION N A COM 989701107 9,847 241,720 SH   SOLE   241,720 0 0
ZOETIS INC CL A 98978V103 4,246 49,634 SH   SOLE   49,634 0 0
ZOGENIX INC COM NEW 98978L204 8,593 235,700 SH   SOLE   235,700 0 0