The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
21VIANET GROUP INC SPONSORED ADR 90138A103 108,858 10,778,004 SH   DFND 5,18 10,778,004 0 0
AC IMMUNE SA SHS H00263105 20,913 2,614,095 SH   DFND 8,17,20 2,614,095 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 170,514 1,226,630 SH   DFND 2,8,11 1,226,630 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 4,776,146 28,988,503 SH   DFND 1,4,14,15,16 28,988,503 0 0
ALTERYX INC COM CL A 02156B103 626 10,939 SH   DFND 7,9 10,939 0 0
AMAZON COM INC COM 023135106 131,934 65,868 SH   DFND 1,14,16 65,868 0 0
AMYRIS INC NOTE 6.500% 5/1 03236MAC5 9,899 10,000,000 PRN   DFND 2,8,11 10,000,000 0 0
ANTERO RES CORP COM 03674X106 172,772 9,755,618 SH   DFND 6,16 9,755,618 0 0
ASLAN PHARMACEUTICALS LTD ADS 04522R101 11,351 1,422,475 SH   DFND 8,17,20 1,422,475 0 0
BEIGENE LTD SPONSORED ADR 07725L102 390,957 2,270,100 SH   DFND 8,17,20 2,270,100 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 230,082 2,372,712 SH   DFND 2,8,11,17,20 2,372,712 0 0
BOEING CO COM 097023105 195,484 525,636 SH   DFND 6,16 525,636 0 0
BP PLC SPONSORED ADR 055622104 27,519 596,946 SH   DFND 6,16 596,946 0 0
BROADCOM INC COM 11135F101 92,783 376,050 SH   DFND 1,14,16 376,050 0 0
CENTURYLINK INC COM 156700106 2,611,866 123,201,207 SH   DFND 1,14,16,18 123,201,207 0 0
CHINA BIOLOGIC PRODS HLDGS I COM G21515104 79,200 990,000 SH   DFND 8,17,20 990,000 0 0
COGNEX CORP COM 192422103 7,770 139,192 SH   DFND 1,14,16 139,192 0 0
COHERUS BIOSCIENCES INC COM 19249H103 108,176 6,556,116 SH   DFND 8,17,20 6,556,116 0 0
COUPA SOFTWARE INC COM 22266L106 4,002 50,597 SH   DFND 7,9 50,597 0 0
CTRIP COM INTL LTD AMERICAN DEP SHS 22943F100 269,740 7,256,928 SH   DFND 1,4,6,14,16 7,256,928 0 0
DENALI THERAPEUTICS INC COM 24823R105 95,883 4,410,457 SH   DFND 8,17,20 4,410,457 0 0
DOWDUPONT INC COM 26078J100 361,428 5,620,090 SH   DFND 6,16 5,620,090 0 0
EMERSON ELEC CO COM 291011104 9,489 123,908 SH   DFND 1,14,16 123,908 0 0
EROS INTL PLC SHS NEW G3788M114 33,201 2,755,310 SH   DFND 4,13,14,16 2,755,310 0 0
EVOQUA WATER TECHNOLOGIES CO COM 30057T105 107,350 6,037,705 SH   DFND 7,9 6,037,705 0 0
FARFETCH LTD ORD SH CL A 30744W107 121,729 4,470,415 SH   DFND 14,16 4,470,415 0 0
FTS INTERNATIONAL INC COM 30283W104 490,666 41,617,144 SH   DFND 7 41,617,144 0 0
GILEAD SCIENCES INC COM 375558103 859,024 11,125,816 SH   DFND 1,8,14,16,17,20 11,125,816 0 0
GLOBAL PMTS INC COM 37940X102 111,625 876,176 SH   DFND 8,10 876,176 0 0
GRACE W R & CO DEL NEW COM 38388F108 156,319 2,187,501 SH   DFND 6,16 2,187,501 0 0
HDFC BANK LTD ADR REPS 3 SHS 40415F101 130,909 1,391,165 SH   DFND 6,16 1,391,165 0 0
HOMOLOGY MEDICINES INC COM 438083107 73,616 3,220,293 SH   DFND 8,17,20 3,220,293 0 0
ICICI BK LTD ADR 45104G104 73,352 8,639,819 SH   DFND 2,6,8,16 8,639,819 0 0
IHS MARKIT LTD SHS G47567105 801,901 14,861,018 SH   DFND 5,18 14,861,018 0 0
ILLUMINA INC COM 452327109 20,354 55,452 SH   DFND 1,14,16 55,452 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 22,625 790,527 SH   DFND 6,8,16,17 790,527 0 0
JD COM INC SPON ADR CL A 47215P106 138,743 5,317,867 SH   DFND 6,16 5,317,867 0 0
KKR REAL ESTATE FIN TR INC COM 48251K100 49,195 2,439,024 SH   DFND 1,14,16 2,439,024 0 0
MASTERCARD INCORPORATED CL A 57636Q104 320,717 1,440,714 SH   DFND 1,8,10,14,16 1,440,714 0 0
NEWFIELD EXPL CO COM 651290108 178,214 6,181,546 SH   DFND 1,14,16 6,181,546 0 0
OKTA INC CL A 679295105 496 7,046 SH   DFND 7,9 7,046 0 0
PAYPAL HLDGS INC COM 70450Y103 535,044 6,091,124 SH   DFND 4,8,10,14,16 6,091,124 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 137,788 5,174,168 SH   DFND 1,2,8,11,14,16,17,20 5,174,168 0 0
PPG INDS INC COM 693506107 188,538 1,727,645 SH   DFND 1,14,16 1,727,645 0 0
REGENERON PHARMACEUTICALS COM 75886F107 51,051 126,351 SH   DFND 8,17,20 126,351 0 0
ROCKWELL AUTOMATION INC COM 773903109 8,328 44,409 SH   DFND 1,14,16 44,409 0 0
ROYAL DUTCH SHELL PLC SPON ADR B 780259107 247,400 3,487,948 SH   DFND 6,16 3,487,948 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 366,873 1,503,087 SH   DFND 2,8,11 1,503,087 0 0
TUNIU CORP SPONSORED ADS CL 89977P106 58,836 8,194,444 SH   DFND 5,18 8,194,444 0 0
TURQUOISE HILL RES LTD COM 900435108 150,111 70,806,995 SH   DFND 3,18,19 70,806,995 0 0
UNIVAR INC COM 91336L107 431,632 14,078,012 SH   DFND 3,18,19 14,078,012 0 0
VIRTU FINL INC CL A 928254101 345,206 16,880,503 SH   DFND 1,7,9,14,16 16,880,503 0 0
VISA INC COM CL A 92826C839 645,536 4,300,992 SH   DFND 1,8,10,14,16 4,300,992 0 0
WORLDPAY INC CL A 981558109 245,700 2,426,186 SH   DFND 1,8,10,14,16 2,426,186 0 0
ZTO EXPRESS CAYMAN INC SPONSORED ADR 98980A105 201,769 12,176,750 SH   DFND 1,14,16 12,176,750 0 0