The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACTIVISION BLIZZARD INC COM 00507V109 23,613 283,850 SH   DFND 01,02 283,850 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 32,316 196,137 SH   DFND 01,02 196,137 0 0
ALPHABET INC CAP STK CL C 02079K305 54,535 45,179 SH   DFND 01,02 45,179 0 0
AMAZON COM INC COM 023135106 58,339 29,126 SH   DFND 01,02 29,126 0 0
AMGEN INC COM 031162100 26,267 126,715 SH   DFND 01,02 126,715 0 0
ANTHEM INC COM 036752103 54,759 199,815 SH   DFND 01,02 199,815 0 0
AON PLC SHS CL A G0408V102 38,876 252,800 SH   DFND 01,02 252,800 0 0
APPLIED MATLS INC COM 038222105 39,014 1,009,410 SH   DFND 01,02 1,009,410 0 0
ARQULE INC COM 04269E107 5,544 979,537 SH   DFND 01,02 979,537 0 0
AT&T INC COM 00206R102 32,676 973,070 SH   DFND 01,02 973,070 0 0
BANK AMER CORP COM 060505104 68,179 2,314,289 SH   DFND 01,02 2,314,289 0 0
BLUEBIRD BIO INC COM 09609G100 20,688 141,700 SH   DFND 01,02 141,700 0 0
BOEING CO COM 097023105 44,383 119,340 SH   DFND 01,02 119,340 0 0
BP PLC SPONSORED ADR 055622104 34,736 753,500 SH   DFND 01,02 753,500 0 0
CARNIVAL CORP UNIT 99/99/9999 143658300 29,933 469,390 SH   DFND 01,02 469,390 0 0
CATERPILLAR INC DEL COM 149123101 37,762 247,635 SH   DFND 01,02 247,635 0 0
CBS CORP NEW CL A 124857202 23,264 404,935 SH   DFND 01,02 404,935 0 0
CENTENE CORP DEL COM 15135B101 52,271 361,035 SH   DFND 01,02 361,035 0 0
CIGNA CORPORATION COM 125509109 14,994 72,000 SH   DFND 01,02 72,000 0 0
CISCO SYS INC COM 17275R102 60,064 1,234,620 SH   DFND 01,02 1,234,620 0 0
CITIGROUP INC COM NEW 172967424 637 8,884 SH   DFND 1 8,884 0 0
CME GROUP INC COM CL A 12572Q105 34,512 202,760 SH   DFND 01,02 202,760 0 0
CONSTELLATION BRANDS INC CL A 21036P108 36,927 171,260 SH   DFND 01,02 171,260 0 0
DISNEY WALT CO COM DISNEY 254687106 66,409 567,890 SH   DFND 01,02 567,890 0 0
DXC TECHNOLOGY CO COM 23355L106 28,114 300,615 SH   DFND 01,02 300,615 0 0
E TRADE FINANCIAL CORP COM NEW 269246401 27,640 527,590 SH   DFND 01,02 527,590 0 0
ELLOMAY CAPITAL LIMITED SHS M39927120 1,201 145,090 SH   DFND 01,02 145,090 0 0
ELOXX PHARMACEUTICALS INC COM 29014R103 32,077 1,882,456 SH   DFND 01,02 1,882,456 0 0
EOG RES INC COM 26875P101 43,067 337,595 SH   DFND 01,02 337,595 0 0
EVOGENE LTD SHS M4119S104 805 258,839 SH   DFND 01,02 258,839 0 0
FACEBOOK INC CL A 30303M102 43,453 264,215 SH   DFND 01,02 264,215 0 0
FEDEX CORP COM 31428X106 45,588 189,327 SH   DFND 01,02 189,327 0 0
GENERAL DYNAMICS CORP COM 369550108 37,872 184,995 SH   DFND 01,02 184,995 0 0
GILAT SATELLITE NETWORKS LTD SHS NEW M51474118 1,824 213,082 SH   DFND 01,02 213,082 0 0
GLOBAL PMTS INC COM 37940X102 59,116 464,020 SH   DFND 01,02 464,020 0 0
GOLDMAN SACHS GROUP INC COM 38141G104 53,619 239,115 SH   DFND 01,02 239,115 0 0
HDFC BANK LTD ADR REPS 3 SHS 40415F101 31,732 337,220 SH   DFND 01,02 337,220 0 0
HOME DEPOT INC COM 437076102 70,342 339,570 SH   DFND 01,02 339,570 0 0
HONEYWELL INTL INC COM 438516106 79,766 479,360 SH   DFND 01,02 479,360 0 0
IMMUNOMEDICS INC COM 452907108 10,621 509,900 SH   DFND 01,02 509,900 0 0
INGERSOLL-RAND PLC SHS G47791101 24,649 240,950 SH   DFND 01,02 240,950 0 0
INTEL CORP COM 458140100 45,495 962,040 SH   DFND 01,02 962,040 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 60,941 813,745 SH   DFND 01,02 813,745 0 0
ITAU UNIBANCO HLDG SA SPON ADR REP PFD 465562106 41,450 3,775,000 SH   DFND 01,02 3,775,000 0 0
JOHNSON & JOHNSON COM 478160104 51,495 372,695 SH   DFND 01,02 372,695 0 0
JPMORGAN CHASE & CO COM 46625H100 52,226 462,835 SH   DFND 01,02 462,835 0 0
KEYCORP NEW COM 493267108 33,216 1,670,000 SH   DFND 01,02 1,670,000 0 0
KIMCO RLTY CORP COM 49446R109 30,309 1,810,600 SH   DFND 01,02 1,810,600 0 0
KOREA ELECTRIC PWR SPONSORED ADR 500631106 462 35,100 SH   DFND 1 35,100 0 0
LEAR CORP COM NEW 521865204 26,228 180,885 SH   DFND 01,02 180,885 0 0
MAGIC SOFTWARE ENTERPRISES L ORD 559166103 1,037 121,951 SH   DFND 1 121,951 0 0
MASTERCARD INCORPORATED CL A 57636Q104 73,769 331,380 SH   DFND 01,02 331,380 0 0
MEDTRONIC PLC SHS G5960L103 45,020 457,655 SH   DFND 01,02 457,655 0 0
MELLANOX TECHNOLOGIES LTD SHS M51363113 85,122 1,158,905 SH   DFND 01,02 1,158,905 0 0
MERCADOLIBRE INC COM 58733R102 14,300 42,000 SH   DFND 01,02 42,000 0 0
MICRON TECHNOLOGY INC COM 595112103 23,563 520,950 SH   DFND 01,02 520,950 0 0
MICROSOFT CORP COM 594918104 71,593 625,975 SH   DFND 01,02 625,975 0 0
MITSUBISHI UFJ FINL GROUP IN SPONSORED ADS 606822104 1,461 236,000 SH   DFND 1 236,000 0 0
MOSAIC CO NEW COM 61945C103 24,675 759,695 SH   DFND 01,02 759,695 0 0
MYLAN N V SHS EURO N59465109 264,422 7,224,654 SH   DFND 01,02 7,224,654 0 0
NEXTERA ENERGY INC COM 65339F101 59,129 352,800 SH   DFND 01,02 352,800 0 0
NIKE INC CL B 654106103 55,938 660,265 SH   DFND 01,02 660,265 0 0
NORTHROP GRUMMAN CORP COM 666807102 42,899 135,170 SH   DFND 01,02 135,170 0 0
NOVA MEASURING INSTRUMENTS L COM M7516K103 47,820 1,817,554 SH   DFND 01,02 1,817,554 0 0
NVIDIA CORP COM 67066G104 25,149 89,491 SH   DFND 01,02 89,491 0 0
ORACLE CORP COM 68389X105 21,342 413,920 SH   DFND 01,02 413,920 0 0
ORMAT TECHNOLOGIES INC COM 686688102 4,350 80,395 SH   DFND 01,02 80,395 0 0
PACKAGING CORP AMER COM 695156109 36,814 335,618 SH   DFND 01,02 335,618 0 0
PAGSEGURO DIGITAL LTD COM CL A G68707101 11,068 400,000 SH   DFND 01,02 400,000 0 0
PAYPAL HLDGS INC COM 70450Y103 26,435 300,950 SH   DFND 01,02 300,950 0 0
PERRIGO CO PLC SHS G97822103 40,710 575,000 SH   DFND 01,02 575,000 0 0
POINTER TELOCATION LTD SHS M7946T104 383 29,435 SH   DFND 01,02 29,435 0 0
REDHILL BIOPHARMA LTD SPONSORED ADS 757468103 3,717 421,000 SH   DFND 01,02 421,000 0 0
REGIONS FINL CORP NEW COM 7591EP100 50,205 2,735,950 SH   DFND 01,02 2,735,950 0 0
RIO TINTO PLC SPONSORED ADR 767204100 35,220 690,318 SH   DFND 01,02 690,318 0 0
SAPIENS INTL CORP N V SHS NEW N7716A151 2,279 172,494 SH   DFND 01,02 172,494 0 0
SIMON PPTY GROUP INC NEW COM 828806109 42,044 237,870 SH   DFND 01,02 237,870 0 0
SODASTREAM INTERNATIONAL LTD USD SHS M9068E105 8,974 62,718 SH   DFND 01,02 62,718 0 0
SOLAREDGE TECHNOLOGIES INC COM COM 83417M104 112,217 2,980,531 SH   DFND 01,02 2,980,531 0 0
STEEL DYNAMICS INC COM 858119100 28,488 630,400 SH   DFND 01,02 630,400 0 0
STRATA SKIN SCIENCES INC COM NEW 86272A206 1,965 555,000 SH   DFND 1 555,000 0 0
T MOBILE US INC COM 872590104 39,603 564,300 SH   DFND 01,02 564,300 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADR 881624209 1,260 58,479 SH   DFND 01,02 58,479 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 64,023 262,305 SH   DFND 01,02 262,305 0 0
TOWER SEMICONDUCTOR LTD SHS NEW M87915274 19,874 913,313 SH   DFND 01,02 913,313 0 0
UNIVERSAL DISPLAY CORP COM 91347P105 11,790 100,000 SH   DFND 01,02 100,000 0 0
UROGEN PHARMA LTD COM M96088105 118,069 2,499,870 SH   DFND 01,02 2,499,870 0 0
VALERO ENERGY CORP NEW COM 91913Y100 35,190 309,365 SH   DFND 01,02 309,365 0 0
VBI VACCINES INC COM NEW 91822J103 8,373 3,459,868 SH   DFND 01,02 3,459,868 0 0
VERIZON COMMUNICATIONS INC COM 92343V104 310 5,800 SH   DFND 1 5,800 0 0
VISA INC COM CL A 92826C839 94,311 628,365 SH   DFND 01,02 628,365 0 0
WALMART INC COM 931142103 67,165 715,210 SH   DFND 01,02 715,210 0 0
WIX COM LTD SHS M98068105 146,226 1,221,600 SH   DFND 01,02 1,221,600 0 0