The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2U INC COM USD0.001 | COM | 90214J101 | 158,511 | 2,108,133 | SH | DFND | 367,467 | 0 | 1,740,666 | ||
| ABIOMED INC | COM | 003654100 | 95,181 | 211,631 | SH | DFND | 50,743 | 0 | 160,888 | ||
| ABRAXAS PETE CORP | COM | 003830106 | 644 | 276,479 | SH | DFND | 5,587 | 0 | 270,892 | ||
| ACACIA COMMUNICATIONS INC COM | COM | 00401C108 | 18,883 | 456,442 | SH | DFND | 135,895 | 0 | 320,547 | ||
| ACTIVISION BLIZZARD INC COM | COM | 00507V109 | 58,294 | 700,735 | SH | DFND | 189,861 | 0 | 510,874 | ||
| ADESTO TECHNOLOGIES CORP COM | COM | 00687D101 | 9,659 | 1,623,331 | SH | DFND | 38,507 | 0 | 1,584,824 | ||
| ADOBE SYS INC | COM | 00724F101 | 99,803 | 369,710 | SH | DFND | 85,154 | 0 | 284,556 | ||
| ADVANCED MICRO DEVICES INC COM | COM | 007903107 | 1,077 | 34,868 | SH | DFND | 10,952 | 0 | 23,916 | ||
| ADYEN NV 144A | COM | N3501V104 | 89,709 | 109,865 | SH | DFND | 29,315 | 0 | 80,550 | ||
| ALASKA COMM SYS GRP INC | COM | 01167P101 | 3,987 | 2,431,163 | SH | DFND | 395,042 | 0 | 2,036,121 | ||
| ALDEYRA THERAPEUTICS USD0.001 | COM | 01438T106 | 3,010 | 218,081 | SH | DFND | 32,435 | 0 | 185,646 | ||
| ALIBABA GROUP HLDG LTD SPONSORED ADS | COM | 01609W102 | 69,565 | 422,218 | SH | DFND | 106,638 | 0 | 315,580 | ||
| ALIGN TECHNOLOGY INC COM | COM | 016255101 | 150,216 | 383,969 | SH | DFND | 32,238 | 0 | 351,731 | ||
| ALLAKOS INC COM | COM | 01671P100 | 1,545 | 34,339 | SH | DFND | 0 | 0 | 34,339 | ||
| ALLEGIANT TRAVEL CO COM | COM | 01748X102 | 12,865 | 101,461 | SH | DFND | 2,328 | 0 | 99,133 | ||
| ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 95,300 | 1,088,895 | SH | DFND | 190,971 | 0 | 897,924 | ||
| ALPHABET INC CAP STK CL A | COM | 02079K305 | 55,946 | 46,348 | SH | DFND | 3,150 | 0 | 43,198 | ||
| ALPHABET INC CAP STK CL C | COM | 02079K107 | 80,412 | 67,377 | SH | DFND | 7,910 | 0 | 59,467 | ||
| AMAZON.COM INC | COM | 023135106 | 543,509 | 271,348 | SH | DFND | 56,440 | 0 | 214,908 | ||
| AMBER ROAD INC COM USD0.001 | COM | 02318Y108 | 724 | 75,248 | SH | DFND | 10,369 | 0 | 64,879 | ||
| AMERICAN EAGLE OUTFITTERS NEW COM | COM | 02553E106 | 87,588 | 3,527,502 | SH | DFND | 245,720 | 0 | 3,281,782 | ||
| AMERICAN TOWER CORPORATION | COM | 03027X100 | 12,095 | 83,241 | SH | DFND | 8,109 | 0 | 75,132 | ||
| AMYRIS INC COM NEW | COM | 03236M200 | 7,828 | 985,839 | SH | DFND | 12,083 | 0 | 973,756 | ||
| APACHE CORP | COM | 037411105 | 10,450 | 219,211 | SH | DFND | 15,527 | 0 | 203,684 | ||
| APPIAN CORP CL A | COM | 03782L101 | 5,511 | 166,492 | SH | DFND | 23,133 | 0 | 143,359 | ||
| APPLE INC | COM | 037833100 | 5,903 | 26,150 | SH | DFND | 6,464 | 0 | 19,686 | ||
| APPLIED OPTOELECTRONICS INC COM | COM | 03823U102 | 414 | 16,770 | SH | DFND | 1,197 | 0 | 15,573 | ||
| AQUANTIA CORP COM | COM | 03842Q108 | 20,841 | 1,629,466 | SH | DFND | 436,428 | 0 | 1,193,038 | ||
| ARCO PLATFORM LTD COM USD0.00005 CL A | COM | G04553106 | 4,560 | 200,000 | SH | DFND | 130 | 0 | 199,870 | ||
| ARISTA NETWORKS INC COM USD0.0001 | COM | 040413106 | 129,842 | 488,384 | SH | DFND | 25,992 | 0 | 462,392 | ||
| ARVINAS INC COM | COM | 04335A105 | 129 | 7,653 | SH | DFND | 139 | 0 | 7,514 | ||
| ASV HLDGS INC COM | COM | 00215L104 | 5,694 | 1,150,252 | SH | DFND | 81,815 | 0 | 1,068,437 | ||
| AT HOME GROUP INC COM | COM | 04650Y100 | 16,339 | 518,192 | SH | DFND | 60,046 | 0 | 458,146 | ||
| ATHENAHEALTH INC DELAWARE | COM | 04685W103 | 352 | 2,635 | SH | DFND | 281 | 0 | 2,354 | ||
| ATHENEX INC COM | COM | 04685N103 | 3,456 | 222,378 | SH | DFND | 27,397 | 0 | 194,981 | ||
| ATLASSIAN CORPORATION PLC COM USD0.1 CL A | COM | G06242104 | 29,221 | 303,945 | SH | DFND | 33,601 | 0 | 270,344 | ||
| AUTO TRADER GROUP PLC ORD GBP0.01 ISIN #GB00BVYVFW23 SEDOL #BVYV | COM | G06708104 | 5,429 | 932,273 | SH | DFND | 179,580 | 0 | 752,693 | ||
| AUTODESK INC COM | COM | 052769106 | 125,921 | 806,619 | SH | DFND | 109,621 | 0 | 696,998 | ||
| AXIS BANK GDR EACH REPR 1 INR10 REG S ISIN #US05462W1099 SEDOL # | COM | 05462W109 | 639 | 15,085 | SH | DFND | 15,000 | 0 | 85 | ||
| AXOGEN INC COM | COM | 05463X106 | 19,319 | 524,268 | SH | DFND | 79,422 | 0 | 444,846 | ||
| AZUL SA SPON ADR EACH REP 3 PFD SHS | COM | 05501U106 | 65,361 | 3,674,045 | SH | DFND | 678,652 | 0 | 2,995,393 | ||
| AZURRX BIOPHARMA INC COM | COM | 05502L105 | 1,430 | 556,537 | SH | DFND | 81,085 | 0 | 475,452 | ||
| BANDWIDTH INC COM CL A | COM | 05988J103 | 25,542 | 476,803 | SH | DFND | 83,842 | 0 | 392,961 | ||
| BARCLAYS BK PLC IPATH S&P 500 VIX SHORT TERM FUTURES ETN NEW 201 | COM | 06746L422 | 85 | 3,198 | SH | DFND | 1,405 | 0 | 1,793 | ||
| BIOSCRIP INC | COM | 09069N108 | 47,695 | 15,385,631 | SH | DFND | 3,513,611 | 0 | 11,872,020 | ||
| BLACK KNIGHT INC COM | COM | 09215C105 | 6,738 | 129,694 | SH | DFND | 1,823 | 0 | 127,871 | ||
| BLOOM ENERGY CORP COM CL A | COM | 093712107 | 1,932 | 56,696 | SH | DFND | 4,700 | 0 | 51,996 | ||
| BLUEBIRD BIO INC COM | COM | 09609G100 | 31,903 | 218,511 | SH | DFND | 65,205 | 0 | 153,306 | ||
| BOSTON SCIENTIFIC CORP | COM | 101137107 | 1,642 | 42,659 | SH | DFND | 19,373 | 0 | 23,286 | ||
| BRIGHTCOVE INC COM USD0.001 | COM | 10921T101 | 251 | 29,872 | SH | DFND | 3,656 | 0 | 26,216 | ||
| CANNAE HLDGS INC COM | COM | 13765N107 | 4,120 | 196,651 | SH | DFND | 38,794 | 0 | 157,857 | ||
| CAREDX INC COM | COM | 14167L103 | 4,685 | 162,405 | SH | DFND | 23,785 | 0 | 138,620 | ||
| CARL ZEISS MEDITEC AG NPV ISIN #DE0005313704 SEDOL #5922961 | COM | D14895102 | 1,472 | 17,599 | SH | DFND | 6,290 | 0 | 11,309 | ||
| CARROLS RESTAURANT GROUP INC COM | COM | 14574X104 | 7,381 | 505,541 | SH | DFND | 49,159 | 0 | 456,382 | ||
| CARVANA CO CL A | COM | 146869102 | 39,242 | 664,100 | SH | DFND | 79,637 | 0 | 584,463 | ||
| CASA SYS INC COM | COM | 14713L102 | 6,724 | 455,836 | SH | DFND | 23,342 | 0 | 432,494 | ||
| CATAPULT GROUP INTERNATIONAL ISIN #AU000000CAT9 SEDOL #BTL0Y76 | COM | Q2159P101 | 176 | 220,746 | SH | DFND | 17,428 | 0 | 203,318 | ||
| CAVCO INDS INC DEL | COM | 149568107 | 100 | 394 | SH | DFND | 60 | 0 | 334 | ||
| CD PROJEKT SA PLN1.00 ISIN #PLOPTTC00011 SEDOL #7302215 | COM | X0957E106 | 1,068 | 21,018 | SH | DFND | 11,619 | 0 | 9,399 | ||
| CHEGG INC COM USD0.001 | COM | 163092109 | 160,247 | 5,636,535 | SH | DFND | 1,011,144 | 0 | 4,625,391 | ||
| CHIPOTLE MEXICAN GRILL INC COM | COM | 169656105 | 18 | 39 | SH | DFND | 11 | 0 | 28 | ||
| CITIGROUP INC COM NEW | COM | 172967424 | 8,166 | 113,831 | SH | DFND | 24,456 | 0 | 89,375 | ||
| CODEXIS INC COM USD0.0001 | COM | 192005106 | 3,767 | 219,666 | SH | DFND | 32,051 | 0 | 187,615 | ||
| CONSTELLATION BRANDS INC CL A | COM | 21036P108 | 3,960 | 18,366 | SH | DFND | 3,353 | 0 | 15,013 | ||
| CONSTRUCTION PARTNERS INC COM CL A | COM | 21044C107 | 3,753 | 310,206 | SH | DFND | 27,478 | 0 | 282,728 | ||
| CORIUM INTL INC COM | COM | 21887L107 | 3,181 | 334,468 | SH | DFND | 49,225 | 0 | 285,243 | ||
| CORNERSTONE ONDEMAND INC COM USD0.0001 | COM | 21925Y103 | 5,829 | 102,708 | SH | DFND | 16,676 | 0 | 86,032 | ||
| COUPA SOFTWARE INC COM | COM | 22266L106 | 18,709 | 236,526 | SH | DFND | 47,172 | 0 | 189,354 | ||
| COVANTA HLDG CORP COM | COM | 22282E102 | 8,305 | 511,069 | SH | DFND | 92,056 | 0 | 419,013 | ||
| CRIMSON WINE GROUP COM USD0.01 | COM | 22662X100 | 615 | 68,703 | SH | DFND | 1,439 | 0 | 67,264 | ||
| DEERE & COMPANY | COM | 244199105 | 15 | 100 | SH | DFND | 0 | 0 | 100 | ||
| DELIVERY HERO SE NPV 144A ISIN #DE000A2E4K43 SEDOL #BZCNB42 | COM | D1T0KZ103 | 510 | 10,609 | SH | DFND | 8,029 | 0 | 2,580 | ||
| DELTA AIR LINES INC DEL COM NEW | COM | 247361702 | 6,937 | 119,960 | SH | DFND | 1,023 | 0 | 118,937 | ||
| DENALI THERAPEUTICS INC COM | COM | 24823R105 | 278 | 12,808 | SH | DFND | 27 | 0 | 12,781 | ||
| DEXCOM INC | COM | 252131107 | 100,198 | 700,487 | SH | DFND | 50,451 | 0 | 650,036 | ||
| DIGI INTL INC COM | COM | 253798102 | 14,942 | 1,110,907 | SH | DFND | 185,797 | 0 | 925,110 | ||
| DOCUSIGN INC COM | COM | 256163106 | 8,648 | 164,512 | SH | DFND | 26,499 | 0 | 138,013 | ||
| DOMO INC COM CL B | COM | 257554105 | 13,417 | 625,510 | SH | DFND | 86,271 | 0 | 539,239 | ||
| ECOSYNTHETIX INC COM ISIN #CA27923D1087 SEDOL #B4XBZ35 | COM | 27923D108 | 89 | 62,782 | SH | DFND | 7,325 | 0 | 55,457 | ||
| EHEALTH INC COM | COM | 28238P109 | 13,035 | 461,261 | SH | DFND | 67,682 | 0 | 393,579 | ||
| ELECTRONIC ARTS | COM | 285512109 | 1,200 | 9,956 | SH | DFND | 2,581 | 0 | 7,375 | ||
| ENPHASE ENERGY INC COM USD0.00001 | COM | 29355A107 | 17,070 | 3,519,549 | SH | DFND | 407,000 | 0 | 3,112,549 | ||
| ENTERCOM COMMUNICATIONS CORP CL A | COM | 293639100 | 8,198 | 1,037,722 | SH | DFND | 107,074 | 0 | 930,648 | ||
| EPAM SYS INC COM USD0.001 | COM | 29414B104 | 81,423 | 591,308 | SH | DFND | 35,042 | 0 | 556,266 | ||
| EROS INTERNATIONAL COM GBP0.30 | COM | G3788M114 | 41,678 | 3,458,747 | SH | DFND | 883,657 | 0 | 2,575,090 | ||
| ESPERION THERAPEUTICS INC COM USD0.001 | COM | 29664W105 | 71 | 1,603 | SH | DFND | 204 | 0 | 1,399 | ||
| ETSY INC COM | COM | 29786A106 | 235,642 | 4,586,261 | SH | DFND | 907,951 | 0 | 3,678,310 | ||
| EVENTBRITE INC COM CL A | COM | 29975E109 | 337 | 8,871 | SH | DFND | 0 | 0 | 8,871 | ||
| EVERBRIDGE INC COM | COM | 29978A104 | 28,974 | 502,675 | SH | DFND | 81,647 | 0 | 421,028 | ||
| EXACT SCIENCES CORP | COM | 30063P105 | 153,814 | 1,948,980 | SH | DFND | 335,595 | 0 | 1,613,385 | ||
| EXTRACTION OIL AND GAS INC COM | COM | 30227M105 | 2,280 | 201,916 | SH | DFND | 12,816 | 0 | 189,100 | ||
| FACEBOOK INC COM USD0.000006 CL A | COM | 30303M102 | 194,190 | 1,180,773 | SH | DFND | 201,263 | 0 | 979,510 | ||
| FARFETCH LTD COM USD0.04 CLASS A | COM | 30744W107 | 67,105 | 2,464,381 | SH | DFND | 166,433 | 0 | 2,297,948 | ||
| FIREEYE INC COM USD0.0001 | COM | 31816Q101 | 399 | 23,468 | SH | DFND | 1,439 | 0 | 22,029 | ||
| FIVE BELOW INC COM | COM | 33829M101 | 136,850 | 1,052,208 | SH | DFND | 71,697 | 0 | 980,511 | ||
| FLEX LNG LTD (BM) USD0.01 ISIN #BMG359471031 SEDOL #BYSYR99 | COM | G35947103 | 1,072 | 589,669 | SH | DFND | 22,842 | 0 | 566,827 | ||
| FLEXION THERAPEUTICS INC COM | COM | 33938J106 | 49,804 | 2,661,900 | SH | DFND | 497,027 | 0 | 2,164,873 | ||
| FLOOR &DECOR HLDGS INC CL A | COM | 339750101 | 26,307 | 871,945 | SH | DFND | 125,003 | 0 | 746,942 | ||
| FORESCOUT TECHNOLOGIES INC COM | COM | 34553D101 | 32,407 | 858,241 | SH | DFND | 133,675 | 0 | 724,566 | ||
| FRANCO NEVADA CORP COM ISIN #CA3518581051 SEDOL #B29NF31 | COM | 351858105 | 5,147 | 82,280 | SH | DFND | 2,715 | 0 | 79,565 | ||
| FRESHPET INC COM | COM | 358039105 | 97,315 | 2,651,647 | SH | DFND | 236,836 | 0 | 2,414,811 | ||
| FUSION CONNECT INC COM | COM | 36116X102 | 805 | 313,401 | SH | DFND | 151,227 | 0 | 162,174 | ||
| GALAPAGOS NV NPV ISIN #BE0003818359 SEDOL #B07Q2V5 | COM | B44170106 | 22,732 | 200,896 | SH | DFND | 100,564 | 0 | 100,332 | ||
| GASLOG LTD COM USD0.01 | COM | G37585109 | 5,551 | 281,046 | SH | DFND | 47,881 | 0 | 233,165 | ||
| GEOPARK LIMITED COM USD0.001 | COM | G38327105 | 3,163 | 155,071 | SH | DFND | 458 | 0 | 154,613 | ||
| GLAUKOS CORP COM | COM | 377322102 | 83,252 | 1,282,781 | SH | DFND | 257,379 | 0 | 1,025,402 | ||
| GLOBANT SA USD1.20 | COM | L44385109 | 46,547 | 789,059 | SH | DFND | 212,195 | 0 | 576,864 | ||
| GLOBUS MED INC CL A NEW | COM | 379577208 | 11,576 | 203,943 | SH | DFND | 37,030 | 0 | 166,913 | ||
| GOGO INC COM | COM | 38046C109 | 357 | 68,773 | SH | DFND | 4,243 | 0 | 64,530 | ||
| GOLAR LNG LIMITED COM STK USD1.00 | COM | G9456A100 | 13,159 | 473,355 | SH | DFND | 78,613 | 0 | 394,742 | ||
| GOLD STD VENTURES CORP COM ISIN #CA3807381049 SEDOL #B05J9S2 | COM | 380738104 | 1,290 | 750,021 | SH | DFND | 9,110 | 0 | 740,911 | ||
| GOLDMAN SACHS GROUP INC | COM | 38141G104 | 82,012 | 365,731 | SH | DFND | 28,397 | 0 | 337,334 | ||
| GOOSEHEAD INS INC COM CL A | COM | 38267D109 | 71,636 | 2,115,033 | SH | DFND | 56,100 | 0 | 2,058,933 | ||
| GOPRO INC CL A | COM | 38268T103 | 15,571 | 2,162,614 | SH | DFND | 216,472 | 0 | 1,946,142 | ||
| GRACE W R & CO DEL NEW | COM | 38388F108 | 15,620 | 218,583 | SH | DFND | 47,433 | 0 | 171,150 | ||
| GRUBHUB INC COM USD0.0001 | COM | 400110102 | 5,855 | 42,237 | SH | DFND | 12,450 | 0 | 29,787 | ||
| GRUPO FINANCIERO GALICIA SA ADR EACH REPR 10 CLASS B ARS1 LVL11 | COM | 399909100 | 2,657 | 104,493 | SH | DFND | 3,789 | 0 | 100,704 | ||
| GTT COMMUNICATIONS INC COM USD0.0001 | COM | 362393100 | 80,132 | 1,846,357 | SH | DFND | 316,464 | 0 | 1,529,893 | ||
| GUIDEWIRE SOFTWARE INC COM USD0.0001 | COM | 40171V100 | 288 | 2,847 | SH | DFND | 2,060 | 0 | 787 | ||
| H &E EQUIPMENT SERVICES INC COM | COM | 404030108 | 2,851 | 75,463 | SH | DFND | 381 | 0 | 75,082 | ||
| HDFC BANK LTD ADS EACH REPR 3 INR10(MGT) | COM | 40415F101 | 46,134 | 490,263 | SH | DFND | 124,467 | 0 | 365,796 | ||
| HEALTHEQUITY INC COM | COM | 42226A107 | 7,288 | 77,193 | SH | DFND | 5,220 | 0 | 71,973 | ||
| HUBSPOT INC COM | COM | 443573100 | 127,058 | 841,720 | SH | DFND | 66,562 | 0 | 775,158 | ||
| ICICI BANK LIMITED ADR EACH REPR 2 ORD INR10(SPON) | COM | 45104G104 | 3,573 | 420,838 | SH | DFND | 9,295 | 0 | 411,543 | ||
| ILLUMINA INC COM | COM | 452327109 | 38,127 | 103,871 | SH | DFND | 9,841 | 0 | 94,030 | ||
| IMPINJ INC COM | COM | 453204109 | 21,404 | 862,364 | SH | DFND | 284,275 | 0 | 578,089 | ||
| INFINERA CORPORATION COM | COM | 45667G103 | 412 | 56,473 | SH | DFND | 3,515 | 0 | 52,958 | ||
| INPHI CORPORATION COM USD0.001 | COM | 45772F107 | 3,943 | 103,816 | SH | DFND | 15,632 | 0 | 88,184 | ||
| INSPIRE MED SYS INC COM | COM | 457730109 | 6,380 | 151,615 | SH | DFND | 13,094 | 0 | 138,521 | ||
| INSULET CORP COM | COM | 45784P101 | 2,293 | 21,645 | SH | DFND | 7,672 | 0 | 13,973 | ||
| INTUITIVE SURGICAL INC COM NEW | COM | 46120E602 | 121,394 | 211,488 | SH | DFND | 16,353 | 0 | 195,135 | ||
| INVITAE CORP COM | COM | 46185L103 | 68,841 | 4,114,826 | SH | DFND | 709,876 | 0 | 3,404,950 | ||
| IRHYTHM TECHNOLOGIES INC COM | COM | 450056106 | 11,911 | 125,830 | SH | DFND | 16,815 | 0 | 109,015 | ||
| IROBOT CORP COM | COM | 462726100 | 8,084 | 73,543 | SH | DFND | 10,440 | 0 | 63,103 | ||
| JD COM INC SPONSORED ADR REPSTG COM CL A | COM | 47215P106 | 63,632 | 2,438,955 | SH | DFND | 453,932 | 0 | 1,985,023 | ||
| JPMORGAN CHASE & CO | COM | 46625H100 | 15,872 | 140,660 | SH | DFND | 33,066 | 0 | 107,594 | ||
| KANSAS CITY SOUTHERN COM | COM | 485170302 | 5,419 | 47,835 | SH | DFND | 3,241 | 0 | 44,594 | ||
| KB HOME COM | COM | 48666K109 | 1,526 | 63,841 | SH | DFND | 12,158 | 0 | 51,683 | ||
| KORNIT DIGITAL LTD ORD ILS0.01 | COM | M6372Q113 | 24,003 | 1,096,038 | SH | DFND | 68,214 | 0 | 1,027,824 | ||
| LENNAR CORP CL B | COM | 526057302 | 159 | 4,134 | SH | DFND | 94 | 0 | 4,040 | ||
| LGI HOMES INC COM | COM | 50187T106 | 77,364 | 1,630,784 | SH | DFND | 214,944 | 0 | 1,415,840 | ||
| LHC GROUP INC COM | COM | 50187A107 | 23,242 | 225,669 | SH | DFND | 39,112 | 0 | 186,557 | ||
| LIBERTY MEDIA CORP DELAWARE COM A BRAVES GRP | COM | 531229706 | 5,626 | 206,227 | SH | DFND | 2,013 | 0 | 204,214 | ||
| LIBERTY MEDIA CORP DELAWARE COM C BRAVES GRP | COM | 531229888 | 17,879 | 656,128 | SH | DFND | 98,152 | 0 | 557,976 | ||
| LIBERTY MEDIA CORP DELAWARE COM SER C FRMLA | COM | 531229854 | 51,288 | 1,379,084 | SH | DFND | 91,452 | 0 | 1,287,632 | ||
| LILIS ENERGY INC COM NEW | COM | 532403201 | 2,419 | 493,662 | SH | DFND | 232,504 | 0 | 261,158 | ||
| LIVANOVA PLC ORD GBP1.00 (DI) | COM | G5509L101 | 167 | 1,344 | SH | DFND | 301 | 0 | 1,043 | ||
| LIVEPERSON INC | COM | 538146101 | 79,631 | 3,068,636 | SH | DFND | 213,953 | 0 | 2,854,683 | ||
| LONZA GROUP AG-REG ISIN #CH0013841017 SEDOL #7333378 | COM | H50524133 | 38,396 | 111,956 | SH | DFND | 45,696 | 0 | 66,260 | ||
| LOVESAC COMPANY COM | COM | 54738L109 | 13,800 | 552,446 | SH | DFND | 4,061 | 0 | 548,385 | ||
| LULULEMON ATHLETICA INC COM | COM | 550021109 | 481 | 2,961 | SH | DFND | 925 | 0 | 2,036 | ||
| LUMENTUM HLDGS INC COM | COM | 55024U109 | 65,239 | 1,088,222 | SH | DFND | 233,231 | 0 | 854,991 | ||
| MADISON SQUARE GARDEN CO NEW CL A | COM | 55825T103 | 8,335 | 26,434 | SH | DFND | 5,216 | 0 | 21,218 | ||
| MAKEMYTRIP LTD USD0.0005 | COM | V5633W109 | 2,839 | 103,439 | SH | DFND | 24,017 | 0 | 79,422 | ||
| MARTIN MARIETTA MATLS INC | COM | 573284106 | 48,606 | 267,137 | SH | DFND | 15,820 | 0 | 251,317 | ||
| MASTERCARD INCORPORATED CL A | COM | 57636Q104 | 21,553 | 96,821 | SH | DFND | 20,151 | 0 | 76,670 | ||
| MATCH GROUP INC COM | COM | 57665R106 | 57,470 | 992,395 | SH | DFND | 323,944 | 0 | 668,451 | ||
| MEDMEN ENTERPRISES INC COM NPV ISIN #CA58507M1077 SEDOL #BYVPJP9 | COM | 58507M107 | 1,655 | 430,387 | SH | DFND | 40,713 | 0 | 389,674 | ||
| MERCADOLIBRE INC | COM | 58733R102 | 45,578 | 133,869 | SH | DFND | 31,454 | 0 | 102,415 | ||
| MERCURY SYS INC COM | COM | 589378108 | 241 | 4,365 | SH | DFND | 1,013 | 0 | 3,352 | ||
| MESA AIR GROUP INC COM NEW | COM | 590479135 | 13,431 | 969,047 | SH | DFND | 65,052 | 0 | 903,995 | ||
| METRO BANK PLC ORD GBP0.000001 ISIN #GB00BZ6STL67 SEDOL #BZ6STL6 | COM | G60640102 | 110,475 | 2,848,594 | SH | DFND | 493,336 | 0 | 2,355,258 | ||
| MICRON TECHNOLOGY | COM | 595112103 | 1,518 | 33,566 | SH | DFND | 12,542 | 0 | 21,024 | ||
| MICROSOFT CORP | COM | 594918104 | 65,145 | 569,595 | SH | DFND | 143,146 | 0 | 426,449 | ||
| MIMECAST LIMITED COM USD0.012 | COM | G14838109 | 1,449 | 34,600 | SH | DFND | 3,427 | 0 | 31,173 | ||
| MOLECULAR TEMPLATES INC COM | COM | 608550109 | 5,438 | 1,008,958 | SH | DFND | 169,982 | 0 | 838,976 | ||
| MONGODB INC CL A | COM | 60937P106 | 117,801 | 1,444,523 | SH | DFND | 158,948 | 0 | 1,285,575 | ||
| MONOLITHIC PWR SYS INC COM | COM | 609839105 | 13,270 | 105,711 | SH | DFND | 6,515 | 0 | 99,196 | ||
| NATERA INC COM | COM | 632307104 | 1,035 | 43,243 | SH | DFND | 18,098 | 0 | 25,145 | ||
| NEOPHOTONICS CORP COM | COM | 64051T100 | 74 | 8,857 | SH | DFND | 2,658 | 0 | 6,199 | ||
| NETFLIX COM INC COM | COM | 64110L106 | 655,409 | 1,751,822 | SH | DFND | 308,296 | 0 | 1,443,526 | ||
| NETSHOES CAYMAN LTD COM USD0.0033 | COM | G6455X107 | 1,520 | 649,387 | SH | DFND | 339,201 | 0 | 310,186 | ||
| NEW RELIC INC COM | COM | 64829B100 | 9,876 | 104,803 | SH | DFND | 19,852 | 0 | 84,951 | ||
| NEW YORK TIMES CO CL A | COM | 650111107 | 106,775 | 4,612,326 | SH | DFND | 1,102,269 | 0 | 3,510,057 | ||
| NINTENDO CO LTD ADR(8 CNV INTO 1 ORD)NPV | COM | 654445303 | 24,510 | 537,173 | SH | DFND | 16,707 | 0 | 520,466 | ||
| NINTENDO CO LTD NPV ISIN #JP3756600007 SEDOL #6639550 | COM | J51699106 | 529 | 1,450 | SH | DFND | 378 | 0 | 1,072 | ||
| NOBLE MIDSTREAM PARTNERS LP COM UNIT REPST | COM | 65506L105 | 39 | 1,111 | SH | DFND | 0 | 0 | 1,111 | ||
| NRG ENERGY INC COM NEW | COM | 629377508 | 599 | 16,008 | SH | DFND | 342 | 0 | 15,666 | ||
| NUTANIX INC CL A | COM | 67059N108 | 242 | 5,670 | SH | DFND | 719 | 0 | 4,951 | ||
| NUVECTRA CORP COM | COM | 67075N108 | 25,687 | 1,168,672 | SH | DFND | 203,104 | 0 | 965,568 | ||
| NV5 GLOBAL INC COM | COM | 62945V109 | 14,077 | 162,370 | SH | DFND | 4,116 | 0 | 158,254 | ||
| NVIDIA CORP | COM | 67066G104 | 60,742 | 216,150 | SH | DFND | 70,756 | 0 | 145,394 | ||
| NXSTAGE MED INC COM | COM | 67072V103 | 369 | 13,237 | SH | DFND | 1,491 | 0 | 11,746 | ||
| OCADO GROUP PLC ORD GBP0.02 ISIN #GB00B3MBS747 SEDOL #B3MBS74 | COM | G6718L106 | 171,879 | 14,657,881 | SH | DFND | 2,449,888 | 0 | 12,207,993 | ||
| OKTA INC CL A | COM | 679295105 | 114,131 | 1,622,105 | SH | DFND | 158,084 | 0 | 1,464,021 | ||
| OVERSTOCK COM INC DEL COM | COM | 690370101 | 9,913 | 357,868 | SH | DFND | 25,806 | 0 | 332,062 | ||
| PALO ALTO NETWORKS INC COM USD0.0001 | COM | 697435105 | 8,316 | 36,917 | SH | DFND | 6,472 | 0 | 30,445 | ||
| PARAMOUNT RESOURCES LIMITED COM NPV CLASS A ISIN #CA6993202069 S | COM | 699320206 | 7,478 | 638,840 | SH | DFND | 44,650 | 0 | 594,190 | ||
| PAYPAL HLDGS INC COM | COM | 70450Y103 | 23,687 | 269,661 | SH | DFND | 32,047 | 0 | 237,614 | ||
| PDF SOLUTIONS INC | COM | 693282105 | 9,410 | 1,042,106 | SH | DFND | 59,575 | 0 | 982,531 | ||
| PDVWIRELESS INC COM | COM | 69290R104 | 198 | 5,836 | SH | DFND | 132 | 0 | 5,704 | ||
| PENSKE AUTOMOTIVE GROUP INC | COM | 70959W103 | 3,479 | 73,410 | SH | DFND | 16,437 | 0 | 56,973 | ||
| PENUMBRA INC COM | COM | 70975L107 | 2,095 | 13,995 | SH | DFND | 2,830 | 0 | 11,165 | ||
| PINDUODUO INC SPON ADS EACH REP 4 ORD SHS | COM | 722304102 | 546 | 20,767 | SH | DFND | 5,090 | 0 | 15,677 | ||
| PIVOTAL SOFTWARE INC COM CL A | COM | 72582H107 | 46,037 | 2,351,220 | SH | DFND | 266,047 | 0 | 2,085,173 | ||
| PLANET FITNESS INC CL A | COM | 72703H101 | 2,123 | 39,294 | SH | DFND | 6,574 | 0 | 32,720 | ||
| PLURALSIGHT INC COM CL A | COM | 72941B106 | 8,389 | 262,155 | SH | DFND | 48,119 | 0 | 214,036 | ||
| POLARITYTE INC COM | COM | 731094108 | 15,397 | 806,122 | SH | DFND | 51,117 | 0 | 755,005 | ||
| POOL CORP COM | COM | 73278L105 | 65,628 | 393,263 | SH | DFND | 60,083 | 0 | 333,180 | ||
| PROOFPOINT INC COM USD0.0001 | COM | 743424103 | 5,528 | 51,987 | SH | DFND | 4,000 | 0 | 47,987 | ||
| PTC INC COM | COM | 69370C100 | 281 | 2,645 | SH | DFND | 1,152 | 0 | 1,493 | ||
| Q2 HLDGS INC COM | COM | 74736L109 | 19,464 | 321,460 | SH | DFND | 47,444 | 0 | 274,016 | ||
| QUANTERIX CORP COM | COM | 74766Q101 | 20,696 | 966,203 | SH | DFND | 141,329 | 0 | 824,874 | ||
| R1 RCM INC COM | COM | 749397105 | 5,167 | 508,526 | SH | DFND | 80,995 | 0 | 427,531 | ||
| RELIANCE INDUSTRIES SPON GDR EACH REP 2 ORD SHS 144A ISIN #US759 | COM | ZZC27DZQ8 | 216 | 6,293 | SH | DFND | 3,166 | 0 | 3,127 | ||
| REPUBLIC FIRST BANCORP INC COM | COM | 760416107 | 529 | 74,049 | SH | DFND | 61,053 | 0 | 12,996 | ||
| RIGHTMOVE ORD GBP0.001 ISIN #GB00BGDT3G23 SEDOL #BGDT3G2 | COM | ZZCHEU4H3 | 17,455 | 2,841,949 | SH | DFND | 227,130 | 0 | 2,614,819 | ||
| RINGCENTRAL INC-CLASS A | COM | 76680R206 | 224,765 | 2,415,526 | SH | DFND | 497,786 | 0 | 1,917,740 | ||
| ROKU INC COM CL A | COM | 77543R102 | 248,712 | 3,405,609 | SH | DFND | 694,428 | 0 | 2,711,181 | ||
| ROYAL GOLD INC COM ISIN #US7802871084 SEDOL #2430553 | COM | 780287108 | 15 | 198 | SH | DFND | 0 | 0 | 198 | ||
| SAFETY INS GROUP INC | COM | 78648T100 | 432 | 4,825 | SH | DFND | 1,075 | 0 | 3,750 | ||
| SAILPOINT TECHNLGIES HLDGS INC COM | COM | 78781P105 | 32,000 | 940,615 | SH | DFND | 99,740 | 0 | 840,875 | ||
| SALESFORCE COM INC | COM | 79466L302 | 101,085 | 635,632 | SH | DFND | 193,330 | 0 | 442,302 | ||
| SANGAMO THERAPEUTICS INC COM | COM | 800677106 | 473 | 27,882 | SH | DFND | 7,213 | 0 | 20,669 | ||
| SAREPTA THERAPEUTICS INC COM | COM | 803607100 | 158,214 | 979,595 | SH | DFND | 228,480 | 0 | 751,115 | ||
| SEASPINE HLDGS CORP COM | COM | 81255T108 | 5,040 | 323,899 | SH | DFND | 60,422 | 0 | 263,477 | ||
| SENESTECH INC COM | COM | 81720R109 | 919 | 1,331,391 | SH | DFND | 109,081 | 0 | 1,222,310 | ||
| SENSEONICS HLDGS INC COM | COM | 81727U105 | 86,459 | 18,125,507 | SH | DFND | 3,936,351 | 0 | 14,189,156 | ||
| SEQUANS COMMUNICATIONS SPON ADR EA REPR 1 ORD SHS | COM | 817323108 | 133 | 93,348 | SH | DFND | 11,443 | 0 | 81,905 | ||
| SERVICENOW INC COM USD0.001 | COM | 81762P102 | 28,264 | 144,478 | SH | DFND | 27,766 | 0 | 116,712 | ||
| SHAKE SHACK INC CL A | COM | 819047101 | 107,503 | 1,706,121 | SH | DFND | 153,613 | 0 | 1,552,508 | ||
| SHERWIN WILLIAMS CO | COM | 824348106 | 1,044 | 2,293 | SH | DFND | 51 | 0 | 2,242 | ||
| SHOPIFY INC COM NPV CL A ISIN #CA82509L1076 SEDOL #BX865C7 | COM | 82509L107 | 41,301 | 251,132 | SH | DFND | 92,798 | 0 | 158,334 | ||
| SHOTSPOTTER INC COM | COM | 82536T107 | 135,187 | 2,205,691 | SH | DFND | 511,788 | 0 | 1,693,903 | ||
| SIENTRA INC COM USD0.01 | COM | 82621J105 | 31,182 | 1,305,772 | SH | DFND | 264,009 | 0 | 1,041,763 | ||
| SILVERCREST METALS INC COM NPV ISIN #CA8283631015 SEDOL #BYVY3D2 | COM | 828363101 | 12,820 | 5,232,755 | SH | DFND | 228,689 | 0 | 5,004,066 | ||
| SITEONE LANDSCAPE SUPPLY INC COM | COM | 82982L103 | 28,866 | 383,149 | SH | DFND | 46,331 | 0 | 336,818 | ||
| SIX FLAGS ENTMT CORP NEW COM | COM | 83001A102 | 7,644 | 109,484 | SH | DFND | 42,430 | 0 | 67,054 | ||
| SKYLINE CHAMPION CORPORATION COM | COM | 830830105 | 12 | 426 | SH | DFND | 87 | 0 | 339 | ||
| SMARTSHEET INC COM CL A | COM | 83200N103 | 1,554 | 49,726 | SH | DFND | 0 | 0 | 49,726 | ||
| SOCIAL CAP HEDOSOPHIA HLDGS CORP UNIT 1 CL A & 1/3 WT EXP ISIN # | COM | G8250R111 | 1,865 | 182,818 | SH | DFND | 33,557 | 0 | 149,261 | ||
| SOLARIS OILFIELD INFRSTR INC COM CL A | COM | 83418M103 | 21,412 | 1,133,501 | SH | DFND | 121,916 | 0 | 1,011,585 | ||
| SPARK THERAPEUTICS INC COM | COM | 84652J103 | 27,992 | 513,140 | SH | DFND | 182,517 | 0 | 330,623 | ||
| SPIRIT AIRLS INC COM | COM | 848577102 | 10,313 | 219,560 | SH | DFND | 7,758 | 0 | 211,802 | ||
| SPLUNK INC COM USD0.001 | COM | 848637104 | 6,170 | 51,031 | SH | DFND | 5,245 | 0 | 45,786 | ||
| SQUARE INC CL A | COM | 852234103 | 150,319 | 1,518,216 | SH | DFND | 139,724 | 0 | 1,378,492 | ||
| SS&C TECHNOLOGIES HLDGS INC COM | COM | 78467J100 | 54,497 | 958,946 | SH | DFND | 149,735 | 0 | 809,211 | ||
| STAAR SURGICAL CO COM NEW PAR $0.01 | COM | 852312305 | 1,117 | 23,263 | SH | DFND | 5,877 | 0 | 17,386 | ||
| STAMPS COM INC COM NEW | COM | 852857200 | 79 | 351 | SH | DFND | 159 | 0 | 192 | ||
| STAR BULK CARRIERS CORP COM USD0.01(POST REV SPLIT) | COM | Y8162K204 | 11,336 | 784,523 | SH | DFND | 134,386 | 0 | 650,137 | ||
| STARS GROUP INC(THE) COM NPV ISIN #CA85570W1005 SEDOL #BDG1MJ0 | COM | 85570W100 | 1,482 | 59,524 | SH | DFND | 1,619 | 0 | 57,905 | ||
| STITCH FIX INC COM CL A | COM | 860897107 | 31,204 | 712,916 | SH | DFND | 0 | 0 | 712,916 | ||
| SUNOPTA INC COM ISIN #CA8676EP1086 SEDOL #2817510 | COM | 8676EP108 | 11,088 | 1,508,545 | SH | DFND | 256,168 | 0 | 1,252,377 | ||
| SUNRUN INC COM | COM | 86771W105 | 540 | 43,426 | SH | DFND | 4,346 | 0 | 39,080 | ||
| SVB FINL GROUP | COM | 78486Q101 | 8,218 | 26,439 | SH | DFND | 5,392 | 0 | 21,047 | ||
| T MOBILE US INC COM | COM | 872590104 | 40,324 | 574,583 | SH | DFND | 50,717 | 0 | 523,866 | ||
| TACTILE SYS TECHNOLOGY INC COM | COM | 87357P100 | 15,852 | 223,113 | SH | DFND | 38,672 | 0 | 184,441 | ||
| TAKEAWAY.COM N.V. EUR0.04 144A ISIN #NL0012015705 SEDOL #BYQ7HZ6 | COM | N84437107 | 5,191 | 80,239 | SH | DFND | 14,693 | 0 | 65,546 | ||
| TAKE-TWO INTERACTIVE SOFTWARE COM | COM | 874054109 | 48,953 | 354,758 | SH | DFND | 126,567 | 0 | 228,191 | ||
| TAL EDUCATION GROUP SPON ADS EACH REP 0.3333 CL A ORD SHS | COM | 874080104 | 32,325 | 1,257,292 | SH | DFND | 98,450 | 0 | 1,158,842 | ||
| TALEND SA ADR EACH REP 1 ORD SHS | COM | 874224207 | 2,525 | 36,203 | SH | DFND | 7,368 | 0 | 28,835 | ||
| TANDEM DIABETES CARE INC COM NEW | COM | 875372203 | 174 | 4,051 | SH | DFND | 1,047 | 0 | 3,004 | ||
| TELADOC HEALTH INC COM | COM | 87918A105 | 129,630 | 1,501,216 | SH | DFND | 461,845 | 0 | 1,039,371 | ||
| TENCENT HOLDINGS LIMITED HKD0.00002 ISIN #KYG875721634 SEDOL #BM | COM | G87572163 | 64,089 | 1,551,639 | SH | DFND | 412,140 | 0 | 1,139,499 | ||
| TESLA INC COM | COM | 88160R101 | 145,061 | 547,877 | SH | DFND | 118,529 | 0 | 429,348 | ||
| TRANSDIGM GROUP INC COM | COM | 893641100 | 6,267 | 16,833 | SH | DFND | 151 | 0 | 16,682 | ||
| TURTLE BEACH CORP COM NEW | COM | 900450206 | 152 | 7,641 | SH | DFND | 1,809 | 0 | 5,832 | ||
| TWITTER INC COM USD0.000005 | COM | 90184L102 | 42,959 | 1,509,452 | SH | DFND | 131,778 | 0 | 1,377,674 | ||
| UBIQUITI NETWORKS INC COM USD0.001 | COM | 90347A100 | 163 | 1,644 | SH | DFND | 206 | 0 | 1,438 | ||
| ULTIMATE SOFTWARE GROUP INC | COM | 90385D107 | 5,044 | 15,654 | SH | DFND | 2,914 | 0 | 12,740 | ||
| UNDER ARMOUR INC COM STK USD0.000333 CLASS A | COM | 904311107 | 242 | 11,390 | SH | DFND | 2,968 | 0 | 8,422 | ||
| UNITY BIOTECHNOLOGY INC COM | COM | 91381U101 | 326 | 20,000 | SH | DFND | 5,644 | 0 | 14,356 | ||
| USA TECHNOLOGIES INC COM NO PAR | COM | 90328S500 | 8,156 | 1,132,718 | SH | DFND | 314,324 | 0 | 818,394 | ||
| VANECK VECTORS ETF TR GOLD MINERS ETF | COM | 92189F106 | 12,717 | 686,653 | SH | DFND | 20,650 | 0 | 666,003 | ||
| VEEVA SYS INC CL A COM | COM | 922475108 | 15,826 | 145,368 | SH | DFND | 27,976 | 0 | 117,392 | ||
| VERIZON COMMUNICATIONS | COM | 92343V104 | 1,973 | 36,959 | SH | DFND | 36,629 | 0 | 330 | ||
| VERRICA PHARMACEUTICALS INC COM | COM | 92511W108 | 2,723 | 167,574 | SH | DFND | 12,148 | 0 | 155,426 | ||
| VIEWRAY INC COM | COM | 92672L107 | 155 | 16,592 | SH | DFND | 8,633 | 0 | 7,959 | ||
| W R BERKLEY CORPORATION COM | COM | 084423102 | 4,836 | 60,502 | SH | DFND | 15,535 | 0 | 44,967 | ||
| WEIGHT WATCHERS INTL INC NEW | COM | 948626106 | 127,209 | 1,767,032 | SH | DFND | 229,246 | 0 | 1,537,786 | ||
| WHEATON PRECIOUS METALS CORP COM NPV ISIN #CA9628791027 SEDOL #B | COM | 962879102 | 1,455 | 83,133 | SH | DFND | 635 | 0 | 82,498 | ||
| WILLSCOT CORP COM | COM | 971375126 | 4,741 | 276,432 | SH | DFND | 49,297 | 0 | 227,135 | ||
| WORKDAY INC COM USD0.001 CL A | COM | 98138H101 | 20,011 | 137,083 | SH | DFND | 27,108 | 0 | 109,975 | ||
| WORLD WRESTLING ENTERTAINMENT INC CL A | COM | 98156Q108 | 178,299 | 1,843,261 | SH | DFND | 306,117 | 0 | 1,537,144 | ||
| ZAI LAB LTD-ADR | COM | 98887Q104 | 16,316 | 837,602 | SH | DFND | 339,325 | 0 | 498,277 | ||
| ZEBRA TECHNOLOGIES CORP CL A | COM | 989207105 | 174 | 982 | SH | DFND | 27 | 0 | 955 | ||
| ZENDESK INC COM USD0.01 | COM | 98936J101 | 10,381 | 146,215 | SH | DFND | 28,947 | 0 | 117,268 | ||
| ZILLOW GROUP INC CL A | COM | 98954M101 | 1,476 | 33,394 | SH | DFND | 6,722 | 0 | 26,672 | ||
| ZILLOW GROUP INC CL C CAP STK | COM | 98954M200 | 7,473 | 168,882 | SH | DFND | 17,913 | 0 | 150,969 | ||
| ZUORA INC COM CL A | COM | 98983V106 | 18,524 | 801,548 | SH | DFND | 82,667 | 0 | 718,881 | ||
| ZYNGA INC COM USD0.00000625 CLASS A | COM | 98986T108 | 11,151 | 2,780,918 | SH | DFND | 458,065 | 0 | 2,322,853 | ||