The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLION PHARMACEUTICALS COM 00448Q201 2,731 948,272 SH   SOLE 948,272 0 0
ADVAXIS INC COM NEW 007624208 701 247,000 SH   SOLE 247,000 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 1,891 349,592 SH   SOLE 349,592 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 6,977 116,770 SH   SOLE 116,770 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 2,018 135,738 SH   SOLE 135,738 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 3,962 346,013 SH   SOLE 346,013 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 1,516 421,000 SH   SOLE 421,000 0 0
AQUINOX PHARMACEUTICALS INC COM 03842B101 1,399 118,928 SH   SOLE 118,928 0 0
ARDELYX INC COM 039697107 1,815 275,059 SH   SOLE 275,059 0 0
ARGENX SE SPONSORED ADR 04016X101 6,023 95,396 SH   SOLE 95,396 0 0
ARQULE INC COM 04269E107 1,150 697,192 SH   SOLE 697,192 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 4,993 124,639 SH   SOLE 124,639 0 0
ATRICURE INC COM 04963C209 7,098 389,145 SH   SOLE 389,145 0 0
BEIGENE LTD SPONSORED ADR 07725L102 5,995 61,349 SH   SOLE 61,349 0 0
BELLICUM PHARMACEUTICALS INC COM 079481107 168 20,000 SH   SOLE 20,000 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 5,859 1,193,228 SH   SOLE 1,193,228 0 0
BIOTELEMETRY INC COM 090672106 2,634 88,100 SH   SOLE 88,100 0 0
BIOTIME INC COM 09066L105 591 275,000 SH   SOLE 275,000 0 0
BLUEBIRD BIO INC COM 09609G100 356 2,000 SH   SOLE 2,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 7,593 100,691 SH   SOLE 100,691 0 0
CARA THERAPEUTICS INC COM 140755109 1,148 93,800 SH   SOLE 93,800 0 0
CASCADIAN THERAPEUTICS INC COM NEW 14740B606 395 106,810 SH   SOLE 106,810 0 0
CIDARA THERAPEUTICS INC COM 171757107 1,472 216,403 SH   SOLE 216,403 0 0
CLEMENTIA PHARMACEUTICALS IN COM 185575107 1,139 60,000 SH   SOLE 60,000 0 0
COGENTIX MEDICAL INC COM 19243A104 1,019 323,482 SH   SOLE 323,482 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 3,323 361,164 SH   SOLE 361,164 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 218 9,619 SH   SOLE 9,619 0 0
DERMIRA INC COM 24983L104 2,392 86,000 SH   SOLE 86,000 0 0
DERMIRA INC NOTE 3.000% 5/1 24983LAA2 1,646 1,500,000 PRN   SOLE 1,500,000 0 0
DEXCOM INC COM 252131107 4,763 83,000 SH   SOLE 83,000 0 0
DEXCOM INC DBCV 0.750% 5/1 252131AE7 236 250,000 PRN   SOLE 250,000 0 0
EDGE THERAPEUTICS INC COM 279870109 182 19,400 SH   SOLE 19,400 0 0
EXACTECH INC COM 30064E109 1,361 27,532 SH   SOLE 27,532 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105 2,120 352,741 SH   SOLE 352,741 0 0
GALAPAGOS NV SPON ADR 36315X101 3,714 39,609 SH   SOLE 39,609 0 0
IMMUNE DESIGN CORP COM 45252L103 1,281 328,500 SH   SOLE 328,500 0 0
IMMUNOMEDICS INC COM 452907108 4,913 304,000 SH   SOLE 304,000 0 0
INOTEK PHARMACEUTICALS CORP NOTE 5.750% 8/0 45780VAB8 452 600,000 PRN   SOLE 600,000 0 0
INSULET CORP COM 45784P101 2,241 32,484 SH   SOLE 32,484 0 0
INSULET CORP NOTE 1.375% 45784PAG6 1,515 1,500,000 PRN   SOLE 1,500,000 0 0
IRONWOOD PHARMACEUTICALS INC DBCV 2.250% 6/1 46333XAD0 670 573,000 PRN   SOLE 573,000 0 0
ISHARES TR NASDQ BIOTECH ETF 464287556 2,787 26,100 SH   SOLE 26,100 0 0
JOHNSON AND JOHNSON COM 478160104 1,313 9,400 SH   SOLE 9,400 0 0
KURA ONCOLOGY INC COM 50127T109 1,794 117,281 SH   SOLE 117,281 0 0
LEAP THERPEUTICS INC COM 52187K101 676 108,330 SH   SOLE 108,330 0 0
LOXO ONCOLOGY INC COM 548862101 24,917 296,000 SH   SOLE 296,000 0 0
LUMINEX CORP DEL COM 55027E102 493 25,000 SH   SOLE 25,000 0 0
MACROGENICS INC COM 556099109 2,930 154,200 SH   SOLE 154,200 0 0
MASIMO CORPORATION COM 574795100 424 5,000 SH   SOLE 5,000 0 0
MINERVA NEUROSCIENCES INC COM 603380106 1,035 171,094 SH   SOLE 171,094 0 0
NATUS MEDICAL INC DEL COM 639050103 302 7,900 SH   SOLE 7,900 0 0
NEOS THERAPEUTICS INC COM 64052L106 281 27,500 SH   SOLE 27,500 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 4,229 54,508 SH   SOLE 54,508 0 0
NXSTAGE MEDICAL INC COM 67072V103 5,237 216,119 SH   SOLE 216,119 0 0
OBSEVA SA COM H5861P103 139 14,225 SH   SOLE 14,225 0 0
PROQR THERAPEUTICS N V SHS EURO N71542109 744 230,770 SH   SOLE 230,770 0 0
PROTALIX BIOTHERAPEUTICS INC NOTE 4.500% 9/1 74365AAB7 2,125 2,500,000 PRN   SOLE 2,500,000 0 0
PROTEOSTASIS THERAPEUTICS IN COM 74373B109 685 117,500 SH   SOLE 117,500 0 0
RADIUS HEALTH INC COM NEW 750469207 1,694 53,309 SH   SOLE 53,309 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 3,758 4,000,000 PRN   SOLE 4,000,000 0 0
REDHILL BIOPHARMA LTD SPONSORED ADR 757468103 180 35,000 SH   SOLE 35,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 3,816 983,478 SH   SOLE 983,478 0 0
SAGE THERAPEUTICS INC COM 78667J108 4,744 28,800 SH   SOLE 28,800 0 0
SCPHARMACEUTICALS INC COM 810648105 1,186 98,100 SH   SOLE 98,100 0 0
SCYNEXIS INC COM 811292101 1,176 506,900 SH   SOLE 506,900 0 0
SPERO THERAPEUTICS INC COM 84833T103 59 5,000 SH   SOLE 5,000 0 0
STEREOTAXIS INC COM 85916J409 1,098 1,372,862 SH   SOLE 1,372,862 0 0
SUNESIS PHARMACEUTICALS INC COM PAR 867328700 2,889 783,000 SH   SOLE 783,000 0 0
VBI VACCINES INC COM NEW 91822J103 4,261 998,000 SH   SOLE 998,000 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 2,606 157,000 SH   SOLE 157,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 1,067 377,695 SH   SOLE 377,695 0 0
ZOGENIX INC COM NEW 98978L204 5,373 134,147 SH   SOLE 134,147 0 0