The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
58.Com Inc Adr SPON ADR REP A 31680Q104 19,154 267,632 SH   DFND 1 267,632 0 0
58.Com Inc Adr SPON ADR REP A 31680Q104 100,958 1,410,618 SH   SOLE 0 1,365,084 0 45,534
58.Com Inc Adr SPON ADR REP A 31680Q104 37,269 520,729 SH   DFND 3 520,729 0 0
58.Com Inc Adr SPON ADR REP A 31680Q104 185,726 2,595,028 SH   DFND 2 2,093,471 0 501,557
ABIOMED COM 003654100 157,875 842,402 SH   DFND 2 619,535 0 222,867
ABIOMED COM 003654100 79,077 421,948 SH   DFND 1 421,948 0 0
ABIOMED COM 003654100 29,535 157,594 SH   DFND 3 157,594 0 0
ABIOMED COM 003654100 98,906 527,750 SH   SOLE 0 516,243 0 11,507
AJ Gallagher & Co COM 363576109 247,362 3,909,001 SH   DFND 2 3,183,134 0 725,867
AJ Gallagher & Co COM 363576109 30,865 487,747 SH   DFND 1 487,747 0 0
AJ Gallagher & Co COM 363576109 44,633 705,331 SH   DFND 3 705,331 0 0
AJ Gallagher & Co COM 363576109 136,089 2,150,586 SH   SOLE 0 2,084,470 0 66,116
Acacia Reasearch Corp ACACIA TCH COM 003881307 582 143,640 SH   DFND 1 143,640 0 0
Acacia Reasearch Corp ACACIA TCH COM 003881307 900 222,180 SH   SOLE 0 222,180 0 0
Activision Blizzard Inc COM 00507V109 19,744 311,820 SH   DFND 1 311,820 0 0
Activision Blizzard Inc COM 00507V109 34,126 538,940 SH   DFND 2 260,965 0 277,975
Activision Blizzard Inc COM 00507V109 546 8,615 SH   DFND 3 8,615 0 0
Activision Blizzard Inc COM 00507V109 7,087 111,924 SH   SOLE 0 111,924 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 5,679 850,204 SH   DFND 1 850,204 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 3,145 470,780 SH   SOLE 0 470,780 0 0
Adaptimmune Therapeutics ADR SPONDS ADR 00653A107 4,005 599,609 SH   DFND 2 325,191 0 274,418
Aduro Biotechnology COM 00739L101 1,631 217,518 SH   SOLE 0 217,518 0 0
Aduro Biotechnology COM 00739L101 3,248 433,033 SH   DFND 2 234,464 0 198,569
Aduro Biotechnology COM 00739L101 2,940 392,062 SH   DFND 1 392,062 0 0
Advanced Micro Devices COM 007903107 15,590 1,516,517 SH   DFND 3 1,516,517 0 0
Advanced Micro Devices COM 007903107 82,610 8,035,955 SH   DFND 2 6,516,703 0 1,519,252
Advanced Micro Devices COM 007903107 8,204 798,102 SH   DFND 1 798,102 0 0
Advanced Micro Devices COM 007903107 44,454 4,324,277 SH   SOLE 0 4,186,568 0 137,709
Aerovironment COM 008073108 6,279 111,810 SH   DFND 1 111,810 0 0
Aerovironment COM 008073108 5,742 102,245 SH   DFND 2 55,382 0 46,863
Aerovironment COM 008073108 9,879 175,900 SH   SOLE 0 175,900 0 0
Albemarle Corp COM 012653101 8,437 65,974 SH   DFND 2 65,974 0 0
Albemarle Corp COM 012653101 7,099 55,506 SH   DFND 1 55,506 0 0
Albemarle Corp COM 012653101 9,071 70,931 SH   SOLE 0 70,931 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 518,279 3,005,734 SH   DFND 1 3,005,734 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 1,641,412 9,519,294 SH   SOLE 0 7,910,653 0 1,608,641
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 108,128 627,083 SH   DFND 3 627,083 0 0
Alibaba Group Holding Sponsored ADR SPONSORED ADS 01609W102 5,442,622 31,564,240 SH   DFND 2 13,077,000 0 18,487,240
Align Technology Inc COM 016255101 2,718 12,232 SH   DFND 2 12,232 0 0
Alnylam Pharmaceuticals COM 02043Q107 82,853 652,127 SH   DFND 1 652,127 0 0
Alnylam Pharmaceuticals COM 02043Q107 189,846 1,494,266 SH   DFND 2 1,111,195 0 383,071
Alnylam Pharmaceuticals COM 02043Q107 26,040 204,962 SH   DFND 3 204,962 0 0
Alnylam Pharmaceuticals COM 02043Q107 160,040 1,259,659 SH   SOLE 0 1,242,271 0 17,388
Alphabet Inc Class A CAP STK CL A 02079K305 25,620 24,321 SH   DFND 1 24,321 0 0
Alphabet Inc Class A CAP STK CL A 02079K305 15,424 14,642 SH   DFND 2 11,212 0 3,430
Alphabet Inc Class A CAP STK CL A 02079K305 86,172 81,804 SH   SOLE 0 81,804 0 0
Alphabet Inc Class A CAP STK CL A 02079K305 532 505 SH   DFND 3 505 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 331,152 316,468 SH   DFND 1 316,468 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 115,512 110,390 SH   DFND 3 110,390 0 0
Alphabet Inc Class C CAP STK CL C 02079K107 1,514,329 1,447,180 SH   DFND 2 813,456 0 633,724
Alphabet Inc Class C CAP STK CL C 02079K107 854,041 816,171 SH   SOLE 0 661,760 0 154,411
Amazon.Com COM 023135106 693,125 592,683 SH   DFND 1 592,683 0 0
Amazon.Com COM 023135106 2,140,215 1,830,073 SH   SOLE 0 1,512,079 0 317,994
Amazon.Com COM 023135106 188,469 161,158 SH   DFND 3 161,158 0 0
Amazon.Com COM 023135106 4,312,346 3,687,436 SH   DFND 2 1,486,698 0 2,200,738
Ambarella SHS G037AX101 3,513 59,800 SH   DFND 1 59,800 0 0
Ambarella SHS G037AX101 3,715 63,232 SH   DFND 2 34,278 0 28,954
Ambarella SHS G037AX101 4,318 73,505 SH   SOLE 0 73,505 0 0
Ameren COM 023608102 14,559 246,800 SH   DFND 1 246,800 0 0
Ameren COM 023608102 908 15,390 SH   DFND 2 15,390 0 0
American Express COM 025816109 34,042 342,790 SH   DFND 1 342,790 0 0
American Express COM 025816109 16,522 166,366 SH   SOLE 0 166,366 0 0
American Express COM 025816109 25,058 252,316 SH   DFND 2 166,229 0 86,087
American Express COM 025816109 879 8,851 SH   DFND 3 8,851 0 0
Analog Devices COM 032654105 12,828 144,085 SH   DFND 1 144,085 0 0
Analog Devices COM 032654105 15,151 170,174 SH   SOLE 0 170,174 0 0
Anthem Inc COM 036752103 113,210 503,131 SH   DFND 3 503,131 0 0
Anthem Inc COM 036752103 320,892 1,426,125 SH   SOLE 0 1,380,159 0 45,966
Anthem Inc COM 036752103 60,331 268,125 SH   DFND 1 268,125 0 0
Anthem Inc COM 036752103 603,419 2,681,741 SH   DFND 2 2,173,048 0 508,693
Apache Corp COM 037411105 33,722 798,732 SH   DFND 1 798,732 0 0
Apache Corp COM 037411105 277,001 6,560,887 SH   DFND 2 5,321,132 0 1,239,755
Apache Corp COM 037411105 50,692 1,200,674 SH   DFND 3 1,200,674 0 0
Apache Corp COM 037411105 152,188 3,604,647 SH   SOLE 0 3,493,364 0 111,283
Apollo Senior Floating Rate COM 037636107 10,020 617,746 SH   DFND 1 617,746 0 0
Apple COM 037833100 9,454 55,867 SH   DFND 1 55,867 0 0
Apple COM 037833100 11,370 67,184 SH   SOLE 0 67,184 0 0
Atlassian Corp Plc CL A G06242104 50,019 1,098,838 SH   DFND 1 1,098,838 0 0
Atlassian Corp Plc CL A G06242104 97,480 2,141,471 SH   SOLE 0 1,145,528 0 995,943
Atlassian Corp Plc CL A G06242104 257,485 5,656,532 SH   DFND 2 2,212,872 0 3,443,660
Autohome Inc - ADR SP ADR RP CL A 05278C107 12,392 191,620 SH   DFND 1 191,620 0 0
Autohome Inc - ADR SP ADR RP CL A 05278C107 115,636 1,788,087 SH   DFND 2 1,426,397 0 361,690
Autohome Inc - ADR SP ADR RP CL A 05278C107 22,594 349,379 SH   DFND 3 349,379 0 0
Autohome Inc - ADR SP ADR RP CL A 05278C107 65,204 1,008,251 SH   SOLE 0 976,612 0 31,639
Avangrid COM 05351W103 16,666 329,500 SH   DFND 1 329,500 0 0
Avangrid COM 05351W103 986 19,500 SH   DFND 2 19,500 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 293,469 1,253,016 SH   DFND 1 1,253,016 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 3,971,791 16,958,245 SH   DFND 2 6,835,438 0 10,122,807
Baidu.com Sponsored ADR SPON ADR REP A 056752108 57,837 246,947 SH   DFND 3 246,947 0 0
Baidu.com Sponsored ADR SPON ADR REP A 056752108 1,021,510 4,361,512 SH   SOLE 0 3,516,281 0 845,231
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 18,303 1,787,373 SH   DFND 1 1,787,373 0 0
Banco Bradesco Pn ADR SP ADR PFD NEW 059460303 127,551 12,456,191 SH   DFND 2 9,844,510 0 2,611,681
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 5,406 171,300 SH   DFND 1 171,300 0 0
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 5,426 171,929 SH   DFND 2 92,892 0 79,037
Baozun Spn Adr 1:1 SPONSORED ADR 06684L103 6,104 193,400 SH   SOLE 0 193,400 0 0
Beigene Ltd SPONSORED ADR 07725L102 2,042 20,901 SH   DFND 1 20,901 0 0
Beigene Ltd SPONSORED ADR 07725L102 6,484 66,350 SH   DFND 2 0 0 66,350
Benefitfocus Inc COM 08180D106 1,990 73,700 SH   DFND 1 73,700 0 0
Benefitfocus Inc COM 08180D106 2,557 94,700 SH   SOLE 0 94,700 0 0
Benefitfocus Inc COM 08180D106 2,633 97,530 SH   DFND 2 52,608 0 44,922
BlackRock Floating Rate Income COM 091941104 16,008 1,150,000 SH   DFND 1 1,150,000 0 0
Blackstone/GSO Strategic Credit Fund COM SHS BEN IN 09257R101 4,438 282,500 SH   DFND 1 282,500 0 0
Blackstone/GSO Strategic Credit Fund COM SHS BEN IN 09257R101 1,653 105,230 SH   DFND 2 105,230 0 0
Blue Capital Reinsurance Holdings Fund (USD) COM G1190F107 7,585 629,438 SH   DFND 1 629,438 0 0
Bluebird Bio Inc COM 09609G100 91,625 514,459 SH   DFND 1 514,459 0 0
Bluebird Bio Inc COM 09609G100 358,782 2,014,495 SH   SOLE 0 1,555,608 0 458,887
Bluebird Bio Inc COM 09609G100 473,654 2,659,481 SH   DFND 2 1,087,039 0 1,572,442
British Amer.Tobacco - ADR SPONSORED ADR 110448107 6,275 93,678 SH   DFND 1 93,678 0 0
British Amer.Tobacco - ADR SPONSORED ADR 110448107 2,018 30,117 SH   SOLE 0 30,117 0 0
CEVA Inc COM 157210105 3,807 82,500 SH   SOLE 0 82,500 0 0
CEVA Inc COM 157210105 3,350 72,589 SH   DFND 2 39,302 0 33,287
CEVA Inc COM 157210105 2,783 60,300 SH   DFND 1 60,300 0 0
CH Robinson Worldwide COM NEW 12541W209 39,638 444,920 SH   DFND 1 444,920 0 0
CH Robinson Worldwide COM NEW 12541W209 238,395 2,675,894 SH   DFND 2 2,194,531 0 481,363
CH Robinson Worldwide COM NEW 12541W209 40,109 450,213 SH   DFND 3 450,213 0 0
CH Robinson Worldwide COM NEW 12541W209 140,226 1,573,983 SH   SOLE 0 1,531,046 0 42,937
CarMax Inc COM 143130102 11,360 177,141 SH   DFND 3 177,141 0 0
CarMax Inc COM 143130102 79,340 1,237,170 SH   DFND 2 1,066,250 0 170,920
CarMax Inc COM 143130102 8,043 125,410 SH   DFND 1 125,410 0 0
CarMax Inc COM 143130102 34,014 530,384 SH   SOLE 0 514,802 0 15,582
Celgene COM 151020104 31,892 305,599 SH   DFND 1 305,599 0 0
Celgene COM 151020104 27,539 263,880 SH   DFND 2 187,168 0 76,712
Celgene COM 151020104 816 7,820 SH   DFND 3 7,820 0 0
Celgene COM 151020104 14,631 140,195 SH   SOLE 0 140,195 0 0
Cemex ADR SPON ADR NEW 151290889 28,799 3,839,805 SH   DFND 1 3,839,805 0 0
Cemex ADR SPON ADR NEW 151290889 6,261 834,782 SH   SOLE 0 834,782 0 0
Cemex ADR SPON ADR NEW 151290889 190,960 25,461,398 SH   DFND 2 11,568,509 0 13,892,889
Chegg COM 163092109 3,877 237,586 SH   DFND 2 129,009 0 108,577
Chegg COM 163092109 5,654 346,469 SH   DFND 1 346,469 0 0
Chegg COM 163092109 8,171 500,646 SH   SOLE 0 500,646 0 0
China Biologic Products Holdings Inc COM G21515104 5,783 73,420 SH   DFND 1 73,420 0 0
China Biologic Products Holdings Inc COM G21515104 58,101 737,597 SH   DFND 2 601,179 0 136,418
China Biologic Products Holdings Inc COM G21515104 31,464 399,436 SH   SOLE 0 386,622 0 12,814
China Biologic Products Holdings Inc COM G21515104 10,818 137,342 SH   DFND 3 137,342 0 0
China Rapid Finance ADR SPONSORED ADR 16953Q105 1,716 300,000 SH   SOLE 0 300,000 0 0
CoStar Group COM 22160N109 8,749 29,463 SH   DFND 2 816 0 28,647
CoStar Group COM 22160N109 883 2,972 SH   DFND 3 2,972 0 0
CoStar Group COM 22160N109 31,534 106,193 SH   DFND 1 106,193 0 0
CoStar Group COM 22160N109 11,183 37,659 SH   SOLE 0 37,659 0 0
Coca Cola COM 191216100 17,232 375,592 SH   DFND 1 375,592 0 0
Coca Cola COM 191216100 20,949 456,615 SH   SOLE 0 456,615 0 0
Codexis COM 192005106 5,724 685,498 SH   DFND 1 685,498 0 0
Codexis COM 192005106 4,653 557,268 SH   DFND 2 301,837 0 255,431
Codexis COM 192005106 5,007 599,635 SH   SOLE 0 599,635 0 0
Consolidated Edison COM 209115104 14,899 175,390 SH   DFND 1 175,390 0 0
Consolidated Edison COM 209115104 899 10,582 SH   DFND 2 10,582 0 0
Copa Holdings S A CL A P31076105 8,617 64,280 SH   DFND 1 64,280 0 0
Copa Holdings S A CL A P31076105 255,353 1,904,763 SH   DFND 2 1,143,881 0 760,882
Copa Holdings S A CL A P31076105 37,385 278,865 SH   SOLE 0 278,865 0 0
Credicorp COM G2519Y108 206,920 997,543 SH   DFND 2 653,652 0 343,891
Credicorp COM G2519Y108 33,755 162,732 SH   SOLE 0 162,732 0 0
Ctrip.com Intl Sponsored ADR AMERICAN DEP SHS 22943F100 117,747 2,670,001 SH   DFND 1 2,670,001 0 0
Ctrip.com Intl Sponsored ADR AMERICAN DEP SHS 22943F100 35,948 815,143 SH   DFND 3 815,143 0 0
Ctrip.com Intl Sponsored ADR AMERICAN DEP SHS 22943F100 1,538,992 34,897,784 SH   DFND 2 15,382,834 0 19,514,950
Ctrip.com Intl Sponsored ADR AMERICAN DEP SHS 22943F100 473,292 10,732,246 SH   SOLE 0 9,013,567 0 1,718,679
Denali Therapeutics COM 24823R105 18,852 1,205,386 SH   DFND 1 1,205,386 0 0
Denali Therapeutics COM 24823R105 5,234 334,653 SH   DFND 2 9,226 0 325,427
Denali Therapeutics COM 24823R105 527 33,702 SH   DFND 3 33,702 0 0
Denali Therapeutics COM 24823R105 52,363 3,348,042 SH   SOLE 0 3,348,042 0 0
Dexcom Inc COM 252131107 42,924 747,933 SH   DFND 1 747,933 0 0
Dexcom Inc COM 252131107 197,538 3,442,033 SH   DFND 2 1,368,968 0 2,073,065
Dexcom Inc COM 252131107 78,086 1,360,618 SH   SOLE 0 761,440 0 599,178
Digimarc COM 25381B101 3,362 93,000 SH   DFND 1 93,000 0 0
Digimarc COM 25381B101 5,255 145,373 SH   DFND 2 78,551 0 66,822
Digimarc COM 25381B101 2,946 81,500 SH   SOLE 0 81,500 0 0
Dolby Laboratories 'A' COM 25659T107 7,657 123,497 SH   DFND 1 123,497 0 0
Dolby Laboratories 'A' COM 25659T107 9,882 159,382 SH   SOLE 0 159,382 0 0
EOG Resources COM 26875P101 305,906 2,834,825 SH   DFND 2 2,336,745 0 498,080
EOG Resources COM 26875P101 30,024 278,236 SH   DFND 1 278,236 0 0
EOG Resources COM 26875P101 54,715 507,045 SH   DFND 3 507,045 0 0
EOG Resources COM 26875P101 152,410 1,412,382 SH   SOLE 0 1,366,845 0 45,537
Eaton Vance Senior Income Trust SH BEN INT 27826S103 12,290 1,885,000 SH   DFND 1 1,885,000 0 0
Ecolab COM 278865100 514 3,832 SH   DFND 1 3,832 0 0
Ecolab COM 278865100 26 196 SH   DFND 2 196 0 0
Edison International COM 281020107 11,718 185,300 SH   DFND 1 185,300 0 0
Edison International COM 281020107 706 11,160 SH   DFND 2 11,160 0 0
Ellie Mae COM 28849P100 14,033 156,965 SH   DFND 2 28,013 0 128,952
Ellie Mae COM 28849P100 40,783 456,186 SH   DFND 1 456,186 0 0
Ellie Mae COM 28849P100 1,001 11,196 SH   DFND 3 11,196 0 0
Ellie Mae COM 28849P100 19,223 215,025 SH   SOLE 0 215,025 0 0
Embraer ADR SP ADR REP 4 COM 29082A107 6,013 251,259 SH   DFND 1 251,259 0 0
Embraer ADR SP ADR REP 4 COM 29082A107 71,900 3,004,576 SH   DFND 2 238,210 0 2,766,366
Estee Lauder 'A' COM 518439104 24,489 192,461 SH   DFND 2 192,461 0 0
Eversource Energy COM 30040W108 15,094 238,900 SH   DFND 1 238,900 0 0
Eversource Energy COM 30040W108 969 15,333 SH   DFND 2 15,333 0 0
Exact Sciences COM 30063P105 4,457 84,831 SH   DFND 1 84,831 0 0
Exact Sciences COM 30063P105 4,791 91,185 SH   DFND 2 49,406 0 41,779
Exact Sciences COM 30063P105 5,776 109,935 SH   SOLE 0 109,935 0 0
Exelon Corporation COM 30161N101 14,973 379,930 SH   DFND 1 379,930 0 0
Exelon Corporation COM 30161N101 954 24,215 SH   DFND 2 24,215 0 0
Facebook Cl.A CL A 30303M102 478,782 2,713,260 SH   DFND 1 2,713,260 0 0
Facebook Cl.A CL A 30303M102 2,030,432 11,506,471 SH   DFND 2 5,386,090 0 6,120,381
Facebook Cl.A CL A 30303M102 68,302 387,067 SH   DFND 3 387,067 0 0
Facebook Cl.A CL A 30303M102 1,113,988 6,312,980 SH   SOLE 0 4,638,261 0 1,674,719
Faro Technologies COM 311642102 3,111 66,200 SH   DFND 1 66,200 0 0
Faro Technologies COM 311642102 5,070 107,880 SH   SOLE 0 107,880 0 0
Faro Technologies COM 311642102 3,710 78,940 SH   DFND 2 42,931 0 36,009
Fastenal COM 311900104 12,433 227,327 SH   DFND 2 227,327 0 0
Fastenal COM 311900104 16,161 295,511 SH   DFND 1 295,511 0 0
Fastenal COM 311900104 21,305 389,557 SH   SOLE 0 389,557 0 0
Ferrari NV COM N3167Y103 1,316,622 12,538,067 SH   DFND 2 5,604,276 0 6,933,791
Ferrari NV COM N3167Y103 240,129 2,286,725 SH   SOLE 0 2,286,725 0 0
Fiat Chrysler Automobiles SHS N31738102 32,061 1,790,732 SH   DFND 1 1,790,732 0 0
Fiat Chrysler Automobiles SHS N31738102 1,148,857 64,167,892 SH   DFND 2 39,049,083 0 25,118,809
Fiat Chrysler Automobiles SHS N31738102 161,977 9,047,002 SH   SOLE 0 8,751,420 0 295,582
Fiat Chrysler Automobiles SHS N31738102 58,683 3,277,694 SH   DFND 3 3,277,694 0 0
Financial Engines COM 317485100 12,646 417,357 SH   DFND 1 417,357 0 0
Financial Engines COM 317485100 17,921 591,466 SH   DFND 3 591,466 0 0
Financial Engines COM 317485100 51,215 1,690,254 SH   SOLE 0 1,641,027 0 49,227
Financial Engines COM 317485100 89,742 2,961,770 SH   DFND 2 2,387,637 0 574,133
First Republic Bank COM 33616C100 241,797 2,790,823 SH   DFND 2 2,162,161 0 628,662
First Republic Bank COM 33616C100 93,104 1,074,603 SH   DFND 1 1,074,603 0 0
First Republic Bank COM 33616C100 35,988 415,370 SH   DFND 3 415,370 0 0
First Republic Bank COM 33616C100 134,262 1,549,650 SH   SOLE 0 1,512,110 0 37,540
First Trust Senior Floating Rate COM 33733U108 2,369 183,676 SH   DFND 1 183,676 0 0
Foamix Pharmaceuticals SHS M46135105 650 108,200 SH   DFND 1 108,200 0 0
Foamix Pharmaceuticals SHS M46135105 668 111,200 SH   SOLE 0 111,200 0 0
Fortive Corp COM 34959J108 36,177 500,028 SH   DFND 1 500,028 0 0
Fortive Corp COM 34959J108 936 12,933 SH   DFND 3 12,933 0 0
Fortive Corp COM 34959J108 20,654 285,476 SH   DFND 2 159,555 0 125,921
Fortive Corp COM 34959J108 16,072 222,142 SH   SOLE 0 222,142 0 0
Foundation Medicine COM 350465100 6,820 100,000 SH   SOLE 0 100,000 0 0
Foundation Medicine COM 350465100 5,101 74,800 SH   DFND 1 74,800 0 0
Foundation Medicine COM 350465100 9,027 132,358 SH   DFND 2 71,576 0 60,782
Glaukos Corp COM 377322102 15,121 589,524 SH   DFND 1 589,524 0 0
Glaukos Corp COM 377322102 4,016 156,567 SH   DFND 2 5,000 0 151,567
Glaukos Corp COM 377322102 408 15,902 SH   DFND 3 15,902 0 0
Glaukos Corp COM 377322102 5,343 208,286 SH   SOLE 0 208,286 0 0
Goldman Sachs Gp. COM 38141G104 19,027 74,687 SH   DFND 2 74,687 0 0
Grubhub Inc COM 400110102 131,986 1,838,251 SH   DFND 1 1,838,251 0 0
Grubhub Inc COM 400110102 256,372 3,570,639 SH   DFND 2 2,553,868 0 1,016,771
Grubhub Inc COM 400110102 43,178 601,366 SH   DFND 3 601,366 0 0
Grubhub Inc COM 400110102 167,830 2,337,465 SH   SOLE 0 2,287,472 0 49,993
HDFC Bank ADR ADR REPS 3 SHS 40415F101 61,231 602,248 SH   DFND 2 499,310 0 102,938
HDFC Bank ADR ADR REPS 3 SHS 40415F101 77,468 761,953 SH   SOLE 0 761,953 0 0
HEICO COM 422806109 9,666 102,445 SH   DFND 1 102,445 0 0
HEICO COM 422806109 641 6,791 SH   DFND 3 6,791 0 0
HEICO COM 422806109 8,616 91,319 SH   SOLE 0 91,319 0 0
HEICO 'A' CL A 422806208 14,061 177,881 SH   DFND 1 177,881 0 0
HEICO 'A' CL A 422806208 18,669 236,168 SH   DFND 2 158,559 0 77,609
Himax Technologies Adr SPONSORED ADR 43289P106 7,042 675,800 SH   DFND 2 0 0 675,800
Howard Hughes COM 44267D107 12,124 92,359 SH   DFND 1 92,359 0 0
Howard Hughes COM 44267D107 121,682 926,958 SH   DFND 2 754,004 0 172,954
Howard Hughes COM 44267D107 23,316 177,618 SH   DFND 3 177,618 0 0
Howard Hughes COM 44267D107 66,045 503,123 SH   SOLE 0 486,495 0 16,628
Hutchison China Meditech SPONSORED ADR 44842L103 2,381 60,404 SH   DFND 1 60,404 0 0
Hutchison China Meditech SPONSORED ADR 44842L103 5,757 146,050 SH   DFND 2 0 0 146,050
ICICI Bank ADR ADR 45104G104 130,442 13,406,199 SH   DFND 2 11,507,444 0 1,898,755
ICICI Bank ADR ADR 45104G104 139,848 14,372,850 SH   SOLE 0 14,372,850 0 0
IPG Photonics Corp COM 44980X109 12,800 59,778 SH   DFND 2 32,342 0 27,436
IPG Photonics Corp COM 44980X109 10,795 50,415 SH   DFND 1 50,415 0 0
IPG Photonics Corp COM 44980X109 18,980 88,636 SH   SOLE 0 88,636 0 0
Illumina COM 452327109 378,150 1,730,745 SH   DFND 1 1,730,745 0 0
Illumina COM 452327109 2,380,356 10,894,577 SH   DFND 2 3,470,237 0 7,424,340
Illumina COM 452327109 2,212 10,122 SH   DFND 3 10,122 0 0
Illumina COM 452327109 1,118,820 5,120,690 SH   SOLE 0 3,907,235 0 1,213,455
Infosys Ltd ADR SPONSORED ADR 456788108 148 9,141 SH   DFND 2 0 0 9,141
Interactive Brokers Group COM 45841N107 177,225 2,993,152 SH   DFND 2 2,369,976 0 623,176
Interactive Brokers Group COM 45841N107 58,458 987,306 SH   DFND 1 987,306 0 0
Interactive Brokers Group COM 45841N107 26,529 448,042 SH   DFND 3 448,042 0 0
Interactive Brokers Group COM 45841N107 94,095 1,589,170 SH   SOLE 0 1,548,584 0 40,586
Intuitive Surgical COM NEW 46120E602 130,609 357,891 SH   DFND 1 357,891 0 0
Intuitive Surgical COM NEW 46120E602 656,435 1,798,748 SH   DFND 2 707,186 0 1,091,562
Intuitive Surgical COM NEW 46120E602 365,014 1,000,202 SH   SOLE 0 675,118 0 325,084
Invesco Senior Income Trust COM 46131H107 43,971 10,016,118 SH   DFND 1 10,016,118 0 0
Invesco Senior Income Trust COM 46131H107 1,995 454,500 SH   DFND 2 454,500 0 0
Ionis Pharmaceuticals COM 462222100 40,535 805,859 SH   DFND 1 805,859 0 0
Ionis Pharmaceuticals COM 462222100 81,411 1,618,504 SH   SOLE 0 870,008 0 748,496
Ionis Pharmaceuticals COM 462222100 210,653 4,187,938 SH   DFND 2 1,585,445 0 2,602,493
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 314,010 24,154,589 SH   DFND 2 8,779,422 0 15,375,167
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 15,781 1,213,941 SH   DFND 1 1,213,941 0 0
Itau Unibanco Holding SA-ADR SPON ADR REP PFD 465562106 24,240 1,864,635 SH   SOLE 0 1,864,635 0 0
JD.Com Inc - ADR SPON ADR CL A 47215P106 72,886 1,759,680 SH   DFND 1 1,759,680 0 0
JD.Com Inc - ADR SPON ADR CL A 47215P106 395,865 9,557,343 SH   DFND 2 3,793,266 0 5,764,077
JD.Com Inc - ADR SPON ADR CL A 47215P106 29,310 707,629 SH   SOLE 0 707,629 0 0
Johnson & Johnson COM 478160104 16,933 121,190 SH   DFND 1 121,190 0 0
Johnson & Johnson COM 478160104 20,848 149,211 SH   SOLE 0 149,211 0 0
Juno Therapeutics Inc COM 48205A109 75,489 1,651,482 SH   DFND 1 1,651,482 0 0
Juno Therapeutics Inc COM 48205A109 259,753 5,682,629 SH   DFND 2 2,231,443 0 3,451,186
Juno Therapeutics Inc COM 48205A109 635 13,882 SH   DFND 3 13,882 0 0
Juno Therapeutics Inc COM 48205A109 146,263 3,199,795 SH   SOLE 0 2,214,179 0 985,616
Kirby COM 497266106 11,525 172,524 SH   DFND 1 172,524 0 0
Kirby COM 497266106 114,955 1,720,885 SH   DFND 2 1,395,012 0 325,873
Kirby COM 497266106 22,025 329,715 SH   DFND 3 329,715 0 0
Kirby COM 497266106 60,664 908,146 SH   SOLE 0 877,354 0 30,792
Korea Electric Power ADR SPONSORED ADR 500631106 866 48,900 SH   DFND 2 48,900 0 0
LendingTree COM 52603B107 32,117 94,336 SH   DFND 1 94,336 0 0
LendingTree COM 52603B107 97,251 285,653 SH   DFND 2 206,391 0 79,262
LendingTree COM 52603B107 12,095 35,526 SH   DFND 3 35,526 0 0
LendingTree COM 52603B107 96,690 284,007 SH   SOLE 0 280,866 0 3,141
Leucadia National COM 527288104 20,272 765,261 SH   DFND 1 765,261 0 0
Leucadia National COM 527288104 202,306 7,637,085 SH   DFND 2 6,180,524 0 1,456,561
Leucadia National COM 527288104 36,458 1,376,305 SH   DFND 3 1,376,305 0 0
Leucadia National COM 527288104 110,052 4,154,476 SH   SOLE 0 4,024,734 0 129,742
Liberty Media Corp DEB 4.00011/1 530715AG6 8,882 13,599,000 SH   DFND 1 13,599,000 0 0
Liberty Media Corp DEB 4.00011/1 530715AG6 1,041 1,594,000 SH   DFND 2 1,594,000 0 0
Lincoln Electric Hdg. COM 533900106 10,847 118,438 SH   DFND 1 118,438 0 0
Lincoln Electric Hdg. COM 533900106 115,484 1,261,017 SH   DFND 2 1,035,946 0 225,071
Lincoln Electric Hdg. COM 533900106 20,786 226,971 SH   DFND 3 226,971 0 0
Lincoln Electric Hdg. COM 533900106 57,863 631,834 SH   SOLE 0 611,173 0 20,661
Lindblad Expeditions Holdings COM 535219109 10,502 1,072,701 SH   SOLE 0 1,072,701 0 0
Line Corp Sponsored Adr SPONSORED ADR 53567X101 21,636 527,838 SH   DFND 2 276,180 0 251,658
Luxoft Holding ORD SHS CL A G57279104 5,399 96,930 SH   DFND 2 0 0 96,930
M&T Bank COM 55261F104 16,065 93,950 SH   DFND 2 93,950 0 0
MakeMyTrip SHS V5633W109 75,585 2,532,150 SH   DFND 2 2,115,692 0 416,458
Markel Corp COM 570535104 67,002 58,819 SH   DFND 1 58,819 0 0
Markel Corp COM 570535104 326,199 286,358 SH   DFND 2 230,117 0 56,241
Markel Corp COM 570535104 55,927 49,096 SH   DFND 3 49,096 0 0
Markel Corp COM 570535104 165,730 145,488 SH   SOLE 0 141,192 0 4,296
MarketAxess Holdings COM 57060D108 38,183 189,261 SH   DFND 3 189,261 0 0
MarketAxess Holdings COM 57060D108 258,178 1,279,695 SH   DFND 2 930,090 0 349,605
MarketAxess Holdings COM 57060D108 148,165 734,400 SH   DFND 1 734,400 0 0
MarketAxess Holdings COM 57060D108 208,529 1,033,602 SH   SOLE 0 1,018,096 0 15,506
Martin Marietta Materials COM 573284106 58,916 266,540 SH   DFND 1 266,540 0 0
Martin Marietta Materials COM 573284106 249,019 1,126,579 SH   DFND 2 899,448 0 227,131
Martin Marietta Materials COM 573284106 42,586 192,664 SH   DFND 3 192,664 0 0
Martin Marietta Materials COM 573284106 136,421 617,179 SH   SOLE 0 600,224 0 16,955
Mastercard Inc-Class A CL A 57636Q104 102,881 679,709 SH   DFND 1 679,709 0 0
Mastercard Inc-Class A CL A 57636Q104 230,954 1,525,862 SH   SOLE 0 1,482,734 0 43,128
Mastercard Inc-Class A CL A 57636Q104 436,047 2,880,857 SH   DFND 2 2,285,878 0 594,979
Mastercard Inc-Class A CL A 57636Q104 73,363 484,695 SH   DFND 3 484,695 0 0
McDonald's COM 580135101 11,713 68,053 SH   DFND 1 68,053 0 0
McDonald's COM 580135101 14,289 83,019 SH   SOLE 0 83,019 0 0
MercadoLibre COM 58733R102 1,613,328 5,127,209 SH   DFND 2 2,310,879 0 2,816,330
MercadoLibre COM 58733R102 50,426 160,254 SH   DFND 1 160,254 0 0
MercadoLibre COM 58733R102 124,092 394,367 SH   SOLE 0 394,367 0 0
Mettler-Toledo COM 592688105 300,618 485,244 SH   DFND 2 359,905 0 125,339
Mettler-Toledo COM 592688105 49,940 80,611 SH   DFND 1 80,611 0 0
Mettler-Toledo COM 592688105 2,427 3,917 SH   DFND 3 3,917 0 0
Mettler-Toledo COM 592688105 29,321 47,328 SH   SOLE 0 47,328 0 0
Microchip Technology COM 595017104 7,264 82,660 SH   DFND 2 82,660 0 0
Microsoft COM 594918104 12,102 141,474 SH   DFND 1 141,474 0 0
Microsoft COM 594918104 28,540 333,643 SH   DFND 2 333,643 0 0
Microsoft COM 594918104 14,563 170,248 SH   SOLE 0 170,248 0 0
Mindbody Cl A COM CL A 60255W105 3,589 117,870 SH   DFND 2 63,569 0 54,301
Mindbody Cl A COM CL A 60255W105 2,656 87,233 SH   DFND 1 87,233 0 0
Mindbody Cl A COM CL A 60255W105 2,894 95,028 SH   SOLE 0 95,028 0 0
Moody's Corp COM 615369105 53,982 365,709 SH   DFND 1 365,709 0 0
Moody's Corp COM 615369105 547,852 3,711,484 SH   DFND 2 3,025,487 0 685,997
Moody's Corp COM 615369105 99,696 675,402 SH   DFND 3 675,402 0 0
Moody's Corp COM 615369105 282,285 1,912,372 SH   SOLE 0 1,849,501 0 62,871
Mulesoft Inc-A CL A 625207105 6,611 284,238 SH   DFND 1 284,238 0 0
Mulesoft Inc-A CL A 625207105 6,171 265,295 SH   DFND 2 143,550 0 121,745
Mulesoft Inc-A CL A 625207105 5,536 238,022 SH   SOLE 0 238,022 0 0
Myriad Genetics Inc COM 62855J104 17,973 523,294 SH   DFND 1 523,294 0 0
Myriad Genetics Inc COM 62855J104 182,613 5,317,027 SH   DFND 2 4,298,562 0 1,018,465
Myriad Genetics Inc COM 62855J104 35,357 1,029,471 SH   DFND 3 1,029,471 0 0
Myriad Genetics Inc COM 62855J104 94,657 2,756,054 SH   SOLE 0 2,664,412 0 91,642
NVIDIA COM 67066G104 233,368 1,206,034 SH   DFND 1 1,206,034 0 0
NVIDIA COM 67066G104 1,212,979 6,268,627 SH   DFND 2 3,147,359 0 3,121,268
NVIDIA COM 67066G104 52,867 273,212 SH   DFND 3 273,212 0 0
NVIDIA COM 67066G104 661,941 3,420,882 SH   SOLE 0 2,608,917 0 811,965
National Instruments Corp COM 636518102 13,220 317,561 SH   DFND 1 317,561 0 0
National Instruments Corp COM 636518102 4,055 97,400 SH   DFND 2 52,809 0 44,591
National Instruments Corp COM 636518102 16,636 399,623 SH   SOLE 0 399,623 0 0
NetEase.com ADR SPONSORED ADR 64110W102 118,720 344,046 SH   DFND 1 344,046 0 0
NetEase.com ADR SPONSORED ADR 64110W102 234,112 678,449 SH   SOLE 0 399,987 0 278,462
NetEase.com ADR SPONSORED ADR 64110W102 9,720 28,169 SH   DFND 3 28,169 0 0
NetEase.com ADR SPONSORED ADR 64110W102 558,936 1,619,775 SH   DFND 2 696,860 0 922,915
Netflix Inc COM 64110L106 2,148 11,188 SH   DFND 3 11,188 0 0
Netflix Inc COM 64110L106 677,827 3,531,083 SH   DFND 2 1,442,151 0 2,088,932
Netflix Inc COM 64110L106 203,817 1,061,767 SH   DFND 1 1,061,767 0 0
Netflix Inc COM 64110L106 451,766 2,353,437 SH   SOLE 0 1,774,368 0 579,069
New Oriental Education & Technology Sponsored ADR SPON ADR 647581107 725,527 7,718,376 SH   DFND 2 2,851,620 0 4,866,756
New Relic COM 64829B100 17,140 296,692 SH   DFND 1 296,692 0 0
New Relic COM 64829B100 4,892 84,683 SH   DFND 2 2,318 0 82,365
New Relic COM 64829B100 484 8,380 SH   DFND 3 8,380 0 0
New Relic COM 64829B100 6,505 112,598 SH   SOLE 0 112,598 0 0
Novocure Ltd ORD SHS G6674U108 4,037 199,849 SH   DFND 1 199,849 0 0
Novocure Ltd ORD SHS G6674U108 3,029 149,971 SH   DFND 2 80,832 0 69,139
Novocure Ltd ORD SHS G6674U108 5,137 254,297 SH   SOLE 0 254,297 0 0
Now Inc/DE COM 67011P100 18,463 1,673,848 SH   DFND 1 1,673,848 0 0
Now Inc/DE COM 67011P100 36,894 3,344,895 SH   SOLE 0 3,247,399 0 97,496
Now Inc/DE COM 67011P100 12,342 1,118,944 SH   DFND 3 1,118,944 0 0
Now Inc/DE COM 67011P100 72,229 6,548,386 SH   DFND 2 5,172,444 0 1,375,942
Nucana Plc ADR SPONSORED ADR 67022C106 3,013 298,000 SH   DFND 1 298,000 0 0
Nucana Plc ADR SPONSORED ADR 67022C106 2,548 252,000 SH   SOLE 0 252,000 0 0
Nuveen Credit Strategies Income Fund COM SHS 67073D102 1,786 217,300 SH   DFND 2 217,300 0 0
Nuveen Credit Strategies Income Fund COM SHS 67073D102 5,839 710,300 SH   DFND 1 710,300 0 0
Nuveen Senior Income Fund COM 67067Y104 12,467 1,915,000 SH   DFND 1 1,915,000 0 0
PG&E Corp COM 69331C108 10,257 228,800 SH   DFND 1 228,800 0 0
PG&E Corp COM 69331C108 587 13,099 SH   DFND 2 13,099 0 0
Pacira Pharmaceuticals COM 695127100 5,186 113,600 SH   DFND 1 113,600 0 0
Pacira Pharmaceuticals COM 695127100 7,147 156,562 SH   DFND 2 84,697 0 71,865
Pacira Pharmaceuticals COM 695127100 4,565 100,000 SH   SOLE 0 100,000 0 0
Penumbra Inc COM 70975L107 2,043 21,708 SH   DFND 1 21,708 0 0
Penumbra Inc COM 70975L107 2,860 30,388 SH   DFND 2 16,491 0 13,897
Penumbra Inc COM 70975L107 2,647 28,131 SH   SOLE 0 28,131 0 0
Pepsico COM 713448108 12,287 102,456 SH   DFND 1 102,456 0 0
Pepsico COM 713448108 14,594 121,694 SH   SOLE 0 121,694 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 15,530 1,509,258 SH   DFND 1 1,509,258 0 0
Petrobras Common ADR SPONSORED ADR 71654V408 119,369 11,600,533 SH   DFND 2 9,302,970 0 2,297,563
Pioneer Floating Rate Trust COM 72369J102 14,186 1,236,803 SH   DFND 1 1,236,803 0 0
PriceSmart COM 741511109 89,927 1,044,446 SH   DFND 2 816,579 0 227,867
PriceSmart COM 741511109 18,059 209,743 SH   SOLE 0 209,743 0 0
Procter & Gamble COM 742718109 14,885 162,003 SH   DFND 1 162,003 0 0
Procter & Gamble COM 742718109 18,287 199,035 SH   SOLE 0 199,035 0 0
Redfin COM 75737F108 19,281 615,622 SH   DFND 1 615,622 0 0
Redfin COM 75737F108 4,742 151,402 SH   DFND 2 4,975 0 146,427
Redfin COM 75737F108 512 16,352 SH   DFND 3 16,352 0 0
Redfin COM 75737F108 6,743 215,284 SH   SOLE 0 215,284 0 0
Regeneron Pharmaceuticals COM 75886F107 2,068 5,500 SH   DFND 2 5,500 0 0
Resmed Inc COM 761152107 22,966 271,174 SH   DFND 1 271,174 0 0
Resmed Inc COM 761152107 121,230 1,431,457 SH   SOLE 0 1,386,503 0 44,954
Resmed Inc COM 761152107 228,155 2,694,005 SH   DFND 2 2,192,963 0 501,042
Resmed Inc COM 761152107 43,973 519,219 SH   DFND 3 519,219 0 0
Restaurant Brands International COM 76131D103 180,790 2,931,554 SH   DFND 2 1,926,659 0 1,004,895
Restaurant Brands International COM 76131D103 29,602 480,000 SH   SOLE 0 480,000 0 0
Rio Tinto Spn.Adr 1:1 SPONSORED ADR 767204100 3,738 70,626 SH   DFND 2 70,626 0 0
Ritchie Bros Auctioneers (USA) COM 767744105 11,564 386,359 SH   DFND 1 386,359 0 0
Ritchie Bros Auctioneers (USA) COM 767744105 172,364 5,758,905 SH   DFND 2 4,710,892 0 1,048,013
Ritchie Bros Auctioneers (USA) COM 767744105 22,940 766,455 SH   DFND 3 766,455 0 0
Ritchie Bros Auctioneers (USA) COM 767744105 62,589 2,091,175 SH   SOLE 0 2,023,283 0 67,892
Ritchie Bros. Auctioneers COM 767744105 49,210 1,638,092 SH   DFND 2 746,849 0 891,243
Ritchie Bros. Auctioneers COM 767744105 16,348 544,193 SH   SOLE 0 544,193 0 0
Royal Crbn.Cruises COM V7780T103 64,894 544,051 SH   DFND 1 544,051 0 0
Royal Crbn.Cruises COM V7780T103 638,446 5,352,500 SH   DFND 2 4,336,004 0 1,016,496
Royal Crbn.Cruises COM V7780T103 120,324 1,008,750 SH   DFND 3 1,008,750 0 0
Royal Crbn.Cruises COM V7780T103 342,269 2,869,459 SH   SOLE 0 2,778,091 0 91,368
Ryanair ADR SPONSORED ADR NE 783513203 653,698 6,274,096 SH   DFND 2 4,514,745 0 1,759,351
Ryanair ADR SPONSORED ADR NE 783513203 5,275 50,626 SH   SOLE 0 50,626 0 0
SEA Ltd ADR ADR 81141R100 8,546 641,104 SH   SOLE 0 641,104 0 0
SEA Ltd ADR ADR 81141R100 37,554 2,817,236 SH   DFND 2 2,817,236 0 0
SEA Ltd ADR ADR 81141R100 4,536 340,289 SH   DFND 1 340,289 0 0
SINA Corp ORD G81477104 5,559 55,423 SH   DFND 1 55,423 0 0
SINA Corp ORD G81477104 37,933 378,161 SH   DFND 2 156,128 0 222,033
Salesforce.com COM 79466L302 73,983 723,694 SH   DFND 1 723,694 0 0
Salesforce.com COM 79466L302 371,965 3,638,514 SH   DFND 2 1,425,263 0 2,213,251
Salesforce.com COM 79466L302 143,534 1,404,029 SH   SOLE 0 752,760 0 651,269
Schlumberger COM 806857108 8,028 119,127 SH   DFND 2 119,127 0 0
Seattle Genetics COM 812578102 86,255 1,612,242 SH   DFND 1 1,612,242 0 0
Seattle Genetics COM 812578102 216,336 4,043,666 SH   SOLE 0 3,108,085 0 935,581
Seattle Genetics COM 812578102 36,643 684,913 SH   DFND 3 684,913 0 0
Seattle Genetics COM 812578102 461,367 8,623,690 SH   DFND 2 4,859,807 0 3,763,883
Sherwin-Williams Co COM 824348106 2,220 5,415 SH   DFND 1 5,415 0 0
Sherwin-Williams Co COM 824348106 9,248 22,555 SH   DFND 2 22,555 0 0
Sherwin-Williams Co COM 824348106 4,295 10,475 SH   SOLE 0 10,475 0 0
Shopify 'A' CL A 82509L107 784 7,763 SH   DFND 3 7,763 0 0
Shopify 'A' CL A 82509L107 58,894 583,112 SH   DFND 2 486,293 0 96,819
Shopify 'A' CL A 82509L107 28,935 286,481 SH   DFND 1 286,481 0 0
Shopify 'A' CL A 82509L107 13,143 130,129 SH   SOLE 0 130,129 0 0
Siteone Landscape Supply COM 82982L103 31,555 411,407 SH   DFND 3 411,407 0 0
Siteone Landscape Supply COM 82982L103 167,229 2,180,295 SH   DFND 2 1,770,245 0 410,050
Siteone Landscape Supply COM 82982L103 16,692 217,627 SH   DFND 1 217,627 0 0
Siteone Landscape Supply COM 82982L103 90,788 1,183,682 SH   SOLE 0 1,147,039 0 36,643
Sohu.com COM 83408W103 4,798 110,684 SH   DFND 1 110,684 0 0
Sohu.com COM 83408W103 24,773 571,474 SH   DFND 2 235,797 0 335,677
Solarcity Corp NOTE 1.625 11/0 83416TAC4 11,180 11,980,000 SH   DFND 1 11,980,000 0 0
Solarcity Corp NOTE 1.625 11/0 83416TAC4 62 66,000 SH   DFND 2 66,000 0 0
Splunk Inc COM 848637104 2,913 35,160 SH   DFND 1 35,160 0 0
Splunk Inc COM 848637104 4,762 57,484 SH   SOLE 0 57,484 0 0
Splunk Inc COM 848637104 5,537 66,837 SH   DFND 2 36,242 0 30,595
Staar Surgical COM PAR $0.01 852312305 3,919 252,867 SH   DFND 2 136,825 0 116,042
Staar Surgical COM PAR $0.01 852312305 3,464 223,490 SH   DFND 1 223,490 0 0
Staar Surgical COM PAR $0.01 852312305 4,899 316,050 SH   SOLE 0 316,050 0 0
Stericycle Inc COM 858912108 9,814 144,339 SH   DFND 1 144,339 0 0
Stericycle Inc COM 858912108 97,093 1,428,053 SH   DFND 2 1,162,362 0 265,691
Stericycle Inc COM 858912108 51,098 751,549 SH   SOLE 0 726,680 0 24,869
Stericycle Inc COM 858912108 18,206 267,779 SH   DFND 3 267,779 0 0
Stitch Fix COM CL A 860897107 19,269 746,001 SH   DFND 1 746,001 0 0
Stitch Fix COM CL A 860897107 5,301 205,225 SH   DFND 2 5,297 0 199,928
Stitch Fix COM CL A 860897107 568 21,972 SH   DFND 3 21,972 0 0
Stitch Fix COM CL A 860897107 7,023 271,898 SH   SOLE 0 271,898 0 0
Stratasys SHS M85548101 2,691 134,800 SH   DFND 1 134,800 0 0
Stratasys SHS M85548101 2,886 144,600 SH   SOLE 0 144,600 0 0
Stratasys SHS M85548101 3,615 181,137 SH   DFND 2 98,050 0 83,087
Sunpower Corp DBCV 4.000 1/1 867652AL3 2,685 3,123,000 SH   DFND 1 3,123,000 0 0
Sunpower Corp DBCV 4.000 1/1 867652AL3 3,469 4,035,000 SH   DFND 2 4,035,000 0 0
TD Ameritrade Holding Corp COM 87236Y108 235,669 4,609,205 SH   DFND 2 3,671,492 0 937,713
TD Ameritrade Holding Corp COM 87236Y108 59,458 1,162,888 SH   DFND 1 1,162,888 0 0
TD Ameritrade Holding Corp COM 87236Y108 37,560 734,596 SH   DFND 3 734,596 0 0
TD Ameritrade Holding Corp COM 87236Y108 127,009 2,484,036 SH   SOLE 0 2,416,493 0 67,543
TJX Companies COM 872540109 8,571 112,103 SH   DFND 1 112,103 0 0
TJX Companies COM 872540109 13,407 175,352 SH   DFND 2 175,352 0 0
TJX Companies COM 872540109 5,508 72,033 SH   SOLE 0 72,033 0 0
TSMC ADR SPONSORED ADR 874039100 1,210,616 30,532,564 SH   DFND 2 22,623,588 0 7,908,976
TSMC ADR SPONSORED ADR 874039100 81,888 2,065,275 SH   DFND 1 2,065,275 0 0
TSMC ADR SPONSORED ADR 874039100 130,815 3,299,253 SH   DFND 3 3,299,253 0 0
TSMC ADR SPONSORED ADR 874039100 353,439 8,913,978 SH   SOLE 0 8,613,048 0 300,930
Tableau Software Class A CL A 87336U105 33,227 480,154 SH   DFND 1 480,154 0 0
Tableau Software Class A CL A 87336U105 8,671 125,297 SH   DFND 2 3,951 0 121,346
Tableau Software Class A CL A 87336U105 876 12,665 SH   DFND 3 12,665 0 0
Tableau Software Class A CL A 87336U105 55,624 803,811 SH   SOLE 0 803,811 0 0
Tal Education Group ADR ADS REPSTG COM 874080104 767,194 25,822,738 SH   DFND 2 6,863,363 0 18,959,375
Teladoc COM 87918A105 2,997 86,000 SH   DFND 1 86,000 0 0
Teladoc COM 87918A105 5,051 144,925 SH   DFND 2 78,512 0 66,413
Teladoc COM 87918A105 4,077 117,000 SH   SOLE 0 117,000 0 0
Teradyne COM 880770102 17,417 415,982 SH   DFND 1 415,982 0 0
Teradyne COM 880770102 91,067 2,174,996 SH   SOLE 0 2,105,184 0 69,812
Teradyne COM 880770102 33,038 789,050 SH   DFND 3 789,050 0 0
Teradyne COM 880770102 227,946 5,444,148 SH   DFND 2 4,664,504 0 779,644
TerraForm Power CL A COM 88104R100 17,801 1,488,357 SH   DFND 1 1,488,357 0 0
TerraForm Power CL A COM 88104R100 1,227 102,571 SH   DFND 2 102,571 0 0
Tesla Inc COM 88160R101 430,616 1,383,062 SH   DFND 1 1,383,062 0 0
Tesla Inc COM 88160R101 2,312,867 7,428,511 SH   DFND 2 2,720,331 0 4,708,180
Tesla Inc COM 88160R101 43,402 139,398 SH   DFND 3 139,398 0 0
Tesla Inc COM 88160R101 1,230,280 3,951,437 SH   SOLE 0 3,164,508 0 786,929
Thermo Fisher Scientific COM 883556102 24,875 131,003 SH   DFND 1 131,003 0 0
Thermo Fisher Scientific COM 883556102 253,117 1,333,035 SH   DFND 2 1,085,734 0 247,301
Thermo Fisher Scientific COM 883556102 135,739 714,866 SH   SOLE 0 692,397 0 22,469
Thermo Fisher Scientific COM 883556102 46,352 244,114 SH   DFND 3 244,114 0 0
Tiffany & Co COM 886547108 1,875 18,036 SH   DFND 1 18,036 0 0
Tiffany & Co COM 886547108 17,605 169,361 SH   DFND 2 169,361 0 0
Tiffany & Co COM 886547108 3,613 34,757 SH   SOLE 0 34,757 0 0
Trupanion COM 898202106 4,972 169,871 SH   DFND 2 92,045 0 77,826
Trupanion COM 898202106 4,683 160,000 SH   DFND 1 160,000 0 0
Trupanion COM 898202106 21,513 735,000 SH   SOLE 0 735,000 0 0
Under Armour Inc Class A CL A 904311107 38,564 2,672,480 SH   DFND 1 2,672,480 0 0
Under Armour Inc Class A CL A 904311107 189,509 13,133,013 SH   DFND 2 5,104,873 0 8,028,140
Under Armour Inc Class A CL A 904311107 95,661 6,629,300 SH   SOLE 0 4,232,125 0 2,397,175
Under Armour Inc Class C CL C 904311206 18,446 1,384,839 SH   DFND 1 1,384,839 0 0
Under Armour Inc Class C CL C 904311206 11,906 893,840 SH   DFND 2 563,752 0 330,088
Under Armour Inc Class C CL C 904311206 7,766 583,001 SH   SOLE 0 583,001 0 0
Under Armour Inc Class C CL C 904311206 505 37,884 SH   DFND 3 37,884 0 0
United Parcel Service CL B 911312106 11,029 92,565 SH   DFND 1 92,565 0 0
United Parcel Service CL B 911312106 13,672 114,745 SH   SOLE 0 114,745 0 0
Vale SA ADR ADR 91912E105 2,050 167,621 SH   DFND 2 167,621 0 0
Varian Medical Systems Inc COM 92220P105 13,046 117,375 SH   DFND 2 117,375 0 0
Veeco Instruments COM 922417100 1,663 112,017 SH   DFND 2 60,585 0 51,432
Veeco Instruments COM 922417100 2,079 140,000 SH   DFND 1 140,000 0 0
Veeco Instruments COM 922417100 11,452 771,205 SH   SOLE 0 771,205 0 0
Verisk Analytics COM 92345Y106 48,549 505,722 SH   DFND 1 505,722 0 0
Verisk Analytics COM 92345Y106 247,947 2,582,780 SH   DFND 2 2,073,097 0 509,683
Verisk Analytics COM 92345Y106 43,757 455,803 SH   DFND 3 455,803 0 0
Verisk Analytics COM 92345Y106 128,928 1,343,004 SH   SOLE 0 1,304,085 0 38,919
Vertex Pharmaceuticals COM 92532F100 34,180 228,080 SH   DFND 1 228,080 0 0
Vertex Pharmaceuticals COM 92532F100 12,367 82,525 SH   SOLE 0 82,525 0 0
Vertex Pharmaceuticals COM 92532F100 951 6,345 SH   DFND 3 6,345 0 0
Vertex Pharmaceuticals COM 92532F100 27,189 181,428 SH   DFND 2 119,618 0 61,810
Visa Inc-Class A Shares COM CL A 92826C839 38,866 340,872 SH   DFND 1 340,872 0 0
Visa Inc-Class A Shares COM CL A 92826C839 388,713 3,409,169 SH   DFND 2 2,769,372 0 639,797
Visa Inc-Class A Shares COM CL A 92826C839 204,884 1,796,910 SH   SOLE 0 1,737,948 0 58,962
Visa Inc-Class A Shares COM CL A 92826C839 71,688 628,729 SH   DFND 3 628,729 0 0
Voya Prime Rate Trust SH BEN INT 92913A100 42,820 8,445,676 SH   DFND 1 8,445,676 0 0
Voya Prime Rate Trust SH BEN INT 92913A100 1,975 389,450 SH   DFND 2 389,450 0 0
WEC Energy Group COM 92939U106 12,615 189,900 SH   DFND 1 189,900 0 0
WEC Energy Group COM 92939U106 944 14,207 SH   DFND 2 14,207 0 0
Wabtec COM 929740108 191,686 2,354,001 SH   DFND 2 1,846,127 0 507,874
Wabtec COM 929740108 47,453 582,744 SH   DFND 1 582,744 0 0
Wabtec COM 929740108 35,319 433,740 SH   DFND 3 433,740 0 0
Wabtec COM 929740108 103,717 1,273,696 SH   SOLE 0 1,236,515 0 37,181
Waters COM 941848103 67,516 349,478 SH   DFND 1 349,478 0 0
Waters COM 941848103 294,680 1,525,338 SH   DFND 2 1,219,389 0 305,949
Waters COM 941848103 48,644 251,791 SH   DFND 3 251,791 0 0
Waters COM 941848103 153,908 796,666 SH   SOLE 0 773,817 0 22,849
Watsco Inc COM 942622200 35,403 208,202 SH   DFND 2 116,172 0 92,030
Watsco Inc COM 942622200 61,225 360,064 SH   DFND 1 360,064 0 0
Watsco Inc COM 942622200 1,611 9,476 SH   DFND 3 9,476 0 0
Watsco Inc COM 942622200 26,487 155,771 SH   SOLE 0 155,771 0 0
Wayfair Inc Class A CL A 94419L101 82,616 1,029,228 SH   DFND 1 1,029,228 0 0
Wayfair Inc Class A CL A 94419L101 35,944 447,789 SH   DFND 2 118,399 0 329,390
Wayfair Inc Class A CL A 94419L101 1,946 24,242 SH   DFND 3 24,242 0 0
Wayfair Inc Class A CL A 94419L101 43,119 537,178 SH   SOLE 0 537,178 0 0
Weibo Corp SPON ADR SPONSORED ADR 948596101 1,237 11,955 SH   DFND 1 11,955 0 0
Weibo Corp SPON ADR SPONSORED ADR 948596101 8,916 86,178 SH   DFND 2 38,605 0 47,573
Wipro Ltd ADR SPON ADR 1 SH 97651M109 131 23,868 SH   DFND 2 0 0 23,868
Wix Com SHS M98068105 138,976 2,414,882 SH   DFND 2 1,758,945 0 655,937
Workday Inc CL A 98138H101 77,034 757,168 SH   DFND 1 757,168 0 0
Workday Inc CL A 98138H101 389,662 3,829,979 SH   DFND 2 1,488,543 0 2,341,436
Workday Inc CL A 98138H101 254,540 2,501,865 SH   SOLE 0 1,818,600 0 683,265
Xylem COM 98419M100 40 581 SH   DFND 2 581 0 0
Xylem COM 98419M100 774 11,352 SH   DFND 1 11,352 0 0
Yandex SHS CLASS A N97284108 14,565 444,726 SH   DFND 1 444,726 0 0
Yandex SHS CLASS A N97284108 77,397 2,363,277 SH   SOLE 0 2,286,413 0 76,864
Yandex SHS CLASS A N97284108 28,613 873,684 SH   DFND 3 873,684 0 0
Yandex SHS CLASS A N97284108 139,647 4,264,039 SH   DFND 2 3,413,928 0 850,111
Zillow Group Inc Class A CL A 98954M101 2,340 57,439 SH   DFND 1 57,439 0 0
Zillow Group Inc Class A CL A 98954M101 28,665 703,604 SH   DFND 2 526,936 0 176,668
Zillow Group Inc Class A CL A 98954M101 5,102 125,231 SH   DFND 3 125,231 0 0
Zillow Group Inc Class A CL A 98954M101 18,714 459,345 SH   SOLE 0 446,526 0 12,819
Zillow Group Inc Class C CL C CAP STK 98954M200 15,728 384,355 SH   DFND 1 384,355 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 88,665 2,166,781 SH   DFND 2 1,722,685 0 444,096
Zillow Group Inc Class C CL C CAP STK 98954M200 15,121 369,517 SH   DFND 3 369,517 0 0
Zillow Group Inc Class C CL C CAP STK 98954M200 49,510 1,209,914 SH   SOLE 0 1,176,044 0 33,870
iRobot COM 462726100 11,324 147,646 SH   DFND 1 147,646 0 0
iRobot COM 462726100 29,891 389,711 SH   SOLE 0 389,711 0 0
iRobot COM 462726100 11,029 143,798 SH   DFND 2 77,880 0 65,918