The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2U INC Common Stock 90214J101 23,658 366,736 SH   OTR   256,746 7,463 102,527
3D SYSTEMS CORP Common Stock 88554D205 1,921 222,296 SH   SOLE   222,296 0 0
ADOBE SYSTEMS INC Common Stock 00724F101 3,314 18,913 SH   SOLE   18,913 0 0
AERONAUTICS LTD Common Stock M0R84M115 176 56,518 SH   SOLE   0 0 0
AEROVIRONMENT INC Common Stock 008073108 7,030 125,183 SH   OTR   43,580 0 81,603
AKAMAI TECHNOLOGIES INC Common Stock 00971T101 2,436 37,448 SH   SOLE   37,448 0 0
ALBEMARLE CORP Common Stock 012653101 1,066 8,333 SH   SOLE   8,333 0 0
ALIBABA GROUP HOLDING-SP ADR ADR 01609W102 16,545 95,952 SH   OTR   56,991 3,823 33,750
ALIGN TECHNOLOGY INC Common Stock 016255101 3,571 16,072 SH   SOLE   16,072 0 0
ALLEGHENY TECHNOLOGIES INC Common Stock 01741R102 72 3,000 SH   SOLE   3,000 0 0
ALLIED MOTION TECHNOLOGIES Common Stock 019330109 1,210 36,578 SH   SOLE   36,578 0 0
ALNYLAM PHARMACEUTICALS INC Common Stock 02043Q107 267 2,098 SH   SOLE   2,098 0 0
ALPHABET INC-CL C Common Stock 02079K107 28,658 27,387 SH   OTR   18,224 967 8,121
AMAZON.COM INC Common Stock 023135106 51,790 44,285 SH   OTR   28,909 1,513 13,607
AMETEK INC Common Stock 031100100 643 8,870 SH   SOLE   8,870 0 0
ANSYS INC Common Stock 03662Q105 2,795 18,935 SH   SOLE   18,935 0 0
APPLE INC Common Stock 037833100 20,334 120,157 SH   OTR   69,535 5,437 44,055
APTIV PLC Common Stock G6095L109 13,387 157,806 SH   OTR   97,335 7,134 53,337
ARCONIC INC Common Stock 03965L100 751 27,553 SH   SOLE   27,553 0 0
ARCTURUS THERAPEUTICS LTD Common Stock M1492T105 610 76,737 SH   SOLE   76,737 0 0
ARKEMA SA Common Stock F0392W125 70 571 SH   SOLE   571 0 0
ARRK CORP Common Stock J0198N101 810 772,548 SH   SOLE   772,548 0 0
ASX Ltd Common Stock Q0604U105 108 2,525 SH   SOLE   0 0 0
ATHENAHEALTH INC Common Stock 04685W103 50,481 379,439 SH   OTR   228,787 14,623 134,238
AUDIOCODES LTD Common Stock M15342104 227 30,895 SH   SOLE   0 0 0
AUTODESK INC Common Stock 052769106 13,523 128,998 SH   OTR   86,943 5,233 36,822
BAIDU INC - SPON ADR ADR 056752108 35,244 150,481 SH   OTR   83,077 4,802 61,927
BAYER AG REG Common Stock D0712D163 49 390 SH   OTR   0 390 0
BERTRANDT AG Common Stock D1014N107 978 8,002 SH   SOLE   8,002 0 0
BEZEQ THE ISRAELI TELECOMMUNICATION CORP LTD Common Stock M2012Q100 255 169,324 SH   SOLE   0 0 0
BIOGEN INC Common Stock 09062X103 2,096 6,579 SH   SOLE   6,579 0 0
BITCOIN GOLD RECEIVABLE Common Stock 07384Q103 501 2,004 SH   SOLE   2,004 0 0
BITCOIN INVESTMENT TRUST Open-End Fund 09173T108 4,376 197,541 SH   OTR   22,334 171,416 3,571
BLACKBERRY LTD Common Stock 09228F103 1,175 105,161 SH   SOLE   105,161 0 0
BLUEBIRD BIO INC Common Stock 09609G100 21,632 121,462 SH   OTR   59,456 5,192 56,814
BOX INC - CLASS A Common Stock 10316T104 2,784 131,811 SH   SOLE   131,811 0 0
BYD CO LTD-UNSPONSORED ADR ADR 05606L100 1,609 92,036 SH   SOLE   92,036 0 0
CAMTEK LTD Common Stock M20791105 259 45,300 SH   SOLE   0 0 0
CARPENTER TECHNOLOGY Common Stock 144285103 85 1,674 SH   SOLE   1,674 0 0
Cboe Global Markets Inc Common Stock 12503M108 91 732 SH   SOLE   0 0 0
CELGENE CORP Common Stock 151020104 1,012 9,695 SH   SOLE   9,695 0 0
CELLCOM ISRAEL LTD Common Stock M2196U109 272 26,332 SH   SOLE   0 0 0
CELLECTIS - ADR ADR 15117K103 1,294 44,382 SH   SOLE   44,382 0 0
CERAGON NETWORKS LTD Common Stock M22013102 245 123,737 SH   SOLE   0 0 0
CERUS CORP Common Stock 157085101 12,048 3,564,373 SH   OTR   2,079,802 31,986 1,452,585
Charles Schwab Corp/The Common Stock 808513105 85 1,662 SH   SOLE   0 0 0
CHECK POINT SOFTWARE TECH Common Stock M22465104 224 2,158 SH   SOLE   0 0 0
CME Group Inc Common Stock 12572Q105 120 820 SH   SOLE   0 0 0
COGNEX CORP Common Stock 192422103 1,098 17,948 SH   SOLE   17,948 0 0
COMPUGEN LTD Common Stock M25722105 5,634 2,253,416 SH   OTR   2,010,753 34,170 143,129
CONFORMIS INC Common Stock 20717E101 930 390,564 SH   SOLE   390,564 0 0
CORNERSTONE ONDEMAND INC Common Stock 21925Y103 1,181 33,434 SH   SOLE   33,434 0 0
CRISPR THERAPEUTICS AG Common Stock H17182108 737 31,388 SH   SOLE   31,388 0 0
CTRIP.COM INTERNATIONAL-ADR ADR 22943F100 6,624 150,213 SH   OTR   64,542 0 85,671
CYBERARK SOFTWARE LTD/ISRAEL Common Stock M2682V108 240 5,810 SH   SOLE   0 0 0
DANEL (ADIR YEOSHUA) LTD Common Stock M27013107 299 5,304 SH   SOLE   0 0 0
DASSAULT SYSTEMES SE Common Stock F2457H472 2,992 28,092 SH   SOLE   28,092 0 0
DEERE & CO Common Stock 244199105 2,940 18,787 SH   SOLE   18,787 0 0
Domino's Pizza Inc Common Stock 25754A201 33 173 SH   SOLE   0 0 0
DOWDUPONT INC Common Stock 26078J100 216 3,032 SH   SOLE   3,032 0 0
EASTMAN CHEMICAL CO Common Stock 277432100 72 774 SH   SOLE   774 0 0
EASTMAN KODAK CO Common Stock 277461406 24 7,728 SH   SOLE   7,728 0 0
EDITAS MEDICINE INC Common Stock 28106W103 34,198 1,112,845 SH   OTR   557,529 62,059 493,257
ELBIT SYSTEMS LTD Common Stock M3760D101 1,392 10,442 SH   SOLE   10,442 0 0
ELBIT SYSTEMS LTD Common Stock M3760D101 228 1,712 SH   SOLE   0 0 0
ELCO LTD Common Stock M3787F105 255 12,514 SH   SOLE   0 0 0
EVOGENE LTD Common Stock M4119S104 97 31,499 SH   SOLE   31,499 0 0
EXONE CO/THE Common Stock 302104104 10,590 1,260,716 SH   OTR   873,160 6,737 380,819
FACEBOOK INC-A Common Stock 30303M102 20,670 117,138 SH   OTR   67,978 4,550 44,152
FANUC CORP Common Stock J15666100 4 220 SH   OTR   0 220 0
FANUC CORP-UNSP ADR ADR 307305102 2,914 121,203 SH   SOLE   121,203 0 0
FARO TECHNOLOGIES INC Common Stock 311642102 724 15,397 SH   SOLE   15,397 0 0
FENNER PLC Common Stock G33656102 79 14,593 SH   SOLE   14,593 0 0
FirstRand Ltd Common Stock S5202Z131 102 18,730 SH   SOLE   0 0 0
Fiserv Inc Common Stock 337738108 118 901 SH   SOLE   0 0 0
FIVE PRIME THERAPEUTICS INC Common Stock 33830X104 947 43,215 SH   SOLE   43,215 0 0
FMS ENTERPRISES MIGUN LTD Common Stock M42619102 236 6,444 SH   SOLE   0 0 0
FOAMIX PHARMACEUTICALS LTD Common Stock M46135105 235 39,160 SH   SOLE   0 0 0
FOUNDATION MEDICINE INC Common Stock 350465100 17,642 258,685 SH   OTR   87,925 8,617 162,143
GEELY AUTOMOBILE-UNSPON ADR ADR 36847Q103 1,352 19,460 SH   SOLE   19,460 0 0
GENERAL ELECTRIC CO Common Stock 369604103 596 34,137 SH   SOLE   34,137 0 0
GENERAL MOTORS CO Common Stock 37045V100 4,786 116,761 SH   OTR   57,043 0 59,718
GILAT SATELLITE NETWORKS LTD Common Stock M51474118 290 36,694 SH   SOLE   0 0 0
GILEAD SCIENCES INC Common Stock 375558103 1,696 23,674 SH   SOLE   23,674 0 0
Guidewire Software Inc Common Stock 40171V100 118 1,585 SH   SOLE   0 0 0
HDFC Bank Ltd ADR 40415F101 81 794 SH   SOLE   0 0 0
HEXAGON AB Common Stock W40063104 617 12,284 SH   SOLE   12,284 0 0
HEXCEL CORP Common Stock 428291108 74 1,194 SH   SOLE   1,194 0 0
HILAN LTD Common Stock M5299H123 282 12,572 SH   SOLE   0 0 0
HORTONWORKS INC Common Stock 440894103 18,537 921,786 SH   OTR   481,472 6,215 428,566
HP INC Common Stock 40434L105 2,478 117,954 SH   SOLE   117,954 0 0
HUBSPOT INC Common Stock 443573100 4,991 56,462 SH   SOLE   56,462 0 0
ILLUMINA INC Common Stock 452327109 36,293 166,109 SH   OTR   84,455 9,768 71,886
IMPINJ INC Common Stock 453204109 2,006 89,057 SH   SOLE   89,057 0 0
INCYTE CORP Common Stock 45337C102 1,042 11,004 SH   SOLE   11,004 0 0
INOVIO PHARMACEUTICALS INC Common Stock 45773H201 1,182 286,277 SH   SOLE   286,277 0 0
INTELLIA THERAPEUTICS INC Common Stock 45826J105 26,430 1,375,149 SH   OTR   953,130 76,777 345,242
Interactive Brokers Group Inc Common Stock 45841N107 30 515 SH   SOLE   0 0 0
International Business Machine Common Stock 459200101 56 366 SH   SOLE   0 0 0
Intuit Inc Common Stock 461202103 146 923 SH   SOLE   0 0 0
INVITAE CORP Common Stock 46185L103 19,112 2,104,798 SH   OTR   1,250,027 19,286 835,485
IONIS PHARMACEUTICALS INC Common Stock 462222100 18,653 370,835 SH   OTR   215,129 3,880 151,826
ITURAN LOCATION AND CONTROL Common Stock M6158M104 233 6,802 SH   SOLE   0 0 0
JD.COM INC-ADR ADR 47215P106 28,079 677,913 SH   OTR   445,809 21,747 206,322
JOUNCE THERAPEUTICS INC Common Stock 481116101 678 53,176 SH   SOLE   53,176 0 0
JUNO THERAPEUTICS INC Common Stock 48205A109 31,197 682,495 SH   OTR   356,390 30,976 295,129
K2M GROUP HOLDINGS INC Common Stock 48273J107 2,335 129,738 SH   SOLE   129,738 0 0
KAMADA LTD Common Stock M6240T109 251 52,695 SH   SOLE   0 0 0
KONINKLIJKE DSM NV Common Stock N5017D122 84 881 SH   SOLE   881 0 0
LENDINGCLUB CORP Common Stock 52603A109 24,001 5,811,387 SH   OTR   3,465,595 261,706 2,042,701
LENDINGTREE INC Common Stock 52603B107 14,811 43,505 SH   OTR   21,317 307 21,059
MAGIC SOFTWARE ENTERPRISES Common Stock 559166103 242 28,561 SH   SOLE   0 0 0
MAGICJACK VOCALTEC LTD Common Stock M6787E101 314 37,211 SH   SOLE   0 0 0
MATERIALISE NV-ADR ADR 57667T100 9,384 738,284 SH   OTR   720,859 4,808 12,617
MATRIX IT LTD Common Stock M6859E153 297 23,472 SH   SOLE   0 0 0
MAZOR ROBOTICS LTD-SPON ADR ADR 57886P103 2,272 44,035 SH   SOLE   39,375 0 0
MEDIDATA SOLUTIONS INC Common Stock 58471A105 20,664 326,079 SH   OTR   205,428 14,746 105,905
MELLANOX TECHNOLOGIES LTD Common Stock M51363113 3,769 58,256 SH   SOLE   52,362 0 0
MENSCH UND MASCHINE SOFTWARE Common Stock D5345W108 1,246 48,859 SH   SOLE   48,859 0 0
MERCADOLIBRE INC Common Stock 58733R102 11,472 36,457 SH   OTR   19,911 0 15,980
MICROSOFT CORP Common Stock 594918104 1,499 17,528 SH   SOLE   17,528 0 0
MSCI Inc Common Stock 55354G100 60 477 SH   SOLE   0 0 0
NANO DIMENSION LTD - ADR ADR 63008G104 186 60,629 SH   SOLE   60,629 0 0
NANOSTRING TECHNOLOGIES INC Common Stock 63009R109 8,507 1,138,821 SH   OTR   1,118,525 20,296 0
Nasdaq Inc Common Stock 631103108 122 1,588 SH   SOLE   0 0 0
NETFLIX INC Common Stock 64110L106 26,728 139,238 SH   OTR   84,911 7,152 47,175
NICE LTD ADR 653656108 287 3,126 SH   SOLE   0 0 0
NINTENDO CO LTD Common Stock J51699106 63 171 SH   OTR   0 171 0
NINTENDO CO LTD-UNSPONS ADR ADR 654445303 10,228 226,928 SH   OTR   128,464 0 98,464
NOVA MEASURING INSTRUMENTS Common Stock M7516K103 220 8,474 SH   SOLE   0 0 0
NVIDIA CORP Common Stock 67066G104 30,505 157,649 SH   OTR   108,479 4,590 43,672
ORBOTECH LTD Common Stock M75253100 293 5,832 SH   SOLE   0 0 0
ORGANOVO HOLDINGS INC Common Stock 68620A104 7,895 5,891,552 SH   OTR   5,829,850 61,702 0
PACIFIC BIOSCIENCES OF CALIF Common Stock 69404D108 565 213,917 SH   SOLE   213,917 0 0
PARTNER COMMUNICATIONS CO Common Stock M78465107 310 48,950 SH   SOLE   0 0 0
PAYPAL HOLDINGS INC Common Stock 70450Y103 11,101 150,785 SH   OTR   95,195 1,572 50,757
PLUG POWER INC Common Stock 72919P202 973 412,391 SH   SOLE   412,391 0 0
PLURISTEM THERAPEUTICS INC Common Stock 72940R102 401 290,922 SH   SOLE   290,922 0 0
POINTER TELOCATION LTD Common Stock M7946T104 279 15,002 SH   SOLE   0 0 0
POLYONE CORPORATION Common Stock 73179P106 74 1,706 SH   SOLE   1,706 0 0
PRAXAIR INC Common Stock 74005P104 76 491 SH   SOLE   491 0 0
PRODWAYS GROUP SA Common Stock F7329W102 2,248 392,776 SH   SOLE   392,776 0 0
PROTO LABS INC Common Stock 743713109 17,316 168,121 SH   OTR   93,206 1,275 73,640
PTC INC Common Stock 69370C100 1,421 23,377 SH   SOLE   23,377 0 0
QUALCOMM INC Common Stock 747525103 1,162 18,147 SH   SOLE   18,147 0 0
RADA ELECTRONIC INDS LTD Common Stock M81863124 225 73,042 SH   SOLE   0 0 0
RADCOM LTD Common Stock M81865111 248 12,470 SH   SOLE   0 0 0
RADWARE LTD Common Stock M81873107 288 14,835 SH   SOLE   0 0 0
Rakuten Inc Common Stock J64264104 97 10,600 SH   SOLE   0 0 0
RED HAT INC Common Stock 756577102 18,696 155,671 SH   OTR   93,918 7,225 53,830
REDFIN CORP Common Stock 75737F108 17,866 570,449 SH   OTR   340,451 23,733 203,108
REDHILL BIOPHARMA LTD-SP ADR ADR 757468103 149 29,040 SH   SOLE   0 0 0
REGENERON PHARMACEUTICALS Common Stock 75886F107 1,038 2,761 SH   SOLE   2,761 0 0
RENISHAW PLC Common Stock G75006117 3,034 42,936 SH   SOLE   42,936 0 0
ROCKWELL AUTOMATION INC Common Stock 773903109 1,232 6,277 SH   SOLE   6,277 0 0
SALESFORCE.COM INC Common Stock 79466L302 23,288 227,803 SH   OTR   132,046 6,411 88,302
SANDVIK AB Common Stock W74857165 71 4,068 SH   SOLE   4,068 0 0
SAPIENS INTERNATIONAL CORP Common Stock N7716A151 213 18,524 SH   SOLE   0 0 0
SBI Holdings Inc/Japan Common Stock J6991H100 180 8,600 SH   SOLE   0 0 0
SERES THERAPEUTICS INC Common Stock 81750R102 16,483 1,625,501 SH   OTR   934,013 80,640 610,848
SERVICENOW INC Common Stock 81762P102 2,933 22,495 SH   SOLE   22,495 0 0
SHOPIFY INC - CLASS A Common Stock 82509L107 3,795 37,573 SH   SOLE   36,982 0 0
SIEMENS AG Common Stock D69671218 799 5,723 SH   SOLE   5,723 0 0
SIGMA LABS INC Common Stock 826598302 35 16,063 SH   SOLE   16,063 0 0
SILICOM LTD Common Stock M84116108 262 3,742 SH   SOLE   0 0 0
SLM SOLUTIONS GROUP AG Common Stock D6T690109 3,937 68,577 SH   SOLE   68,577 0 0
SOFTBANK GROUP CORP Common Stock J75963108 44 555 SH   OTR   0 555 0
SOFTBANK GROUP CORP-UNSP ADR ADR 83404D109 19,344 486,580 SH   OTR   326,281 17,421 139,391
SOLAREDGE TECHNOLOGIES INC Common Stock 83417M104 315 8,382 SH   SOLE   0 0 0
SPLUNK INC Common Stock 848637104 20,244 244,377 SH   OTR   154,057 10,550 78,467
SQUARE INC - A Common Stock 852234103 23,464 676,779 SH   OTR   376,788 29,977 260,165
Starbucks Corp Common Stock 855244109 98 1,707 SH   SOLE   0 0 0
STRATASYS LTD Common Stock M85548101 55,120 2,761,525 SH   OTR   1,571,565 105,719 1,072,073
SUNY CELLULAR COMMUNICATION Common Stock M8708U107 228 363,578 SH   SOLE   0 0 0
SYROS PHARMACEUTICALS INC Common Stock 87184Q107 8,122 834,757 SH   OTR   629,973 11,439 193,345
TARO PHARMACEUTICAL INDUS Common Stock M8737E108 247 2,356 SH   SOLE   0 0 0
TELADOC INC Common Stock 87918A105 1,092 31,321 SH   SOLE   31,321 0 0
TENCENT HOLDINGS LTD-UNS ADR ADR 88032Q109 22,059 424,860 SH   OTR   261,420 14,266 143,930
TERADYNE INC Common Stock 880770102 12,850 306,909 SH   OTR   178,201 16,243 112,465
TESLA INC Common Stock 88160R101 43,869 140,900 SH   OTR   132,916 7,984 0
TEVA PHARMACEUTICAL-SP ADR ADR 881624209 325 17,164 SH   SOLE   0 0 0
TORAY INDUSTRIES INC Common Stock J89494116 70 7,392 SH   SOLE   7,392 0 0
TOWER SEMICONDUCTOR LTD Common Stock M87915274 278 8,162 SH   SOLE   0 0 0
TOYOTA MOTOR CORP -SPON ADR ADR 892331307 1,863 14,646 SH   SOLE   14,646 0 0
Trade Me Group Ltd Common Stock Q9162N106 55 15,998 SH   SOLE   0 0 0
TransUnion Common Stock 89400J107 99 1,803 SH   SOLE   0 0 0
TRIMBLE INC Common Stock 896239100 3,416 84,044 SH   SOLE   84,044 0 0
TWILIO INC - A Common Stock 90138F102 3,696 156,620 SH   OTR   153,666 2,954 0
TWITTER INC Common Stock 90184L102 53,199 2,215,686 SH   OTR   1,288,625 84,547 842,514
ULTRA CLEAN HOLDINGS INC Common Stock 90385V107 549 23,758 SH   SOLE   23,758 0 0
UNITED PARCEL SERVICE-CL B Common Stock 911312106 703 5,896 SH   SOLE   5,896 0 0
UROGEN PHARMA LTD Common Stock M96088105 345 9,284 SH   SOLE   0 0 0
VASCULAR BIOGENICS LTD Common Stock M96883109 302 42,484 SH   SOLE   0 0 0
VERACYTE INC Common Stock 92337F107 9,157 1,402,264 SH   OTR   1,386,031 16,233 0
Verisk Analytics Inc Common Stock 92345Y106 33 344 SH   SOLE   0 0 0
Visa Inc Common Stock 92826C839 69 602 SH   SOLE   0 0 0
Wirecard AG ADR 97654L108 33 597 SH   SOLE   0 0 0
WIX.COM LTD Common Stock M98068105 215 3,742 SH   SOLE   0 0 0
Workday Inc Common Stock 98138H101 68 671 SH   SOLE   0 0 0
Xero Ltd Common Stock Q98665104 71 3,196 SH   SOLE   0 0 0
XILINX INC Common Stock 983919101 18,983 281,568 SH   OTR   178,714 8,786 94,068