The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
58 COM INC SPON ADR REP A 31680Q104 240,953 3,816,181 SH   SOLE 3,816,181 0 224,500
ACADIA PHARMACEUTICALS INC COM 004225108 1,216 32,300 SH   SOLE 32,300 0 0
ACCELERON PHARMA INC COM 00434H108 2,183 58,500 SH   SOLE 58,500 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 1,827 37,600 SH   SOLE 37,600 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 2,389 35,800 SH   SOLE 35,800 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 415,720 2,407,045 SH   SOLE 2,407,045 0 181,800
ALLY FINL INC COM 02005N100 24,876 1,025,400 SH   SOLE 1,025,400 0 0
ALPHABET INC CAP STK CL A 02079K305 174,005 178,702 SH   SOLE 178,702 0 16,890
ALPHABET INC CAP STK CL C 02079K107 210,554 219,531 SH   SOLE 219,531 0 21,986
AMEC FOSTER WHEELER PLC SPONSORED ADR 00167X205 202 29,908 SH   SOLE 29,908 0 0
APPLE INC COM 037833100 3,652 23,700 SH   SOLE 23,700 0 0
BAIDU INC SPON ADR REP A 056752108 175,310 707,780 SH   SOLE 707,780 0 31,455
BARRICK GOLD CORP COM 067901108 9,438 586,595 SH   SOLE 586,595 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 1,286 13,820 SH   SOLE 13,820 0 0
Bitauto Hlds Ltd SPONSORED ADS 091727107 87,378 1,955,658 SH   SOLE 1,955,658 0 0
CALLAWAY GOLF CO COM 131193104 22,727 1,575,000 SH   SOLE 1,575,000 0 0
CARNIVAL CORP UNIT 99/99/9999 143658300 10,328 159,955 SH   SOLE 159,955 0 0
CISCO SYS INC COM 17275R102 1,200 35,700 SH   SOLE 35,700 0 0
COCA COLA CO COM 191216100 118,949 2,642,733 SH   SOLE 2,642,733 0 158,000
COHERUS BIOSCIENCES INC COM 19249H103 1,457 109,200 SH   SOLE 109,200 0 0
CONFORMIS INC COM 20717E101 1,179 335,156 SH   SOLE 335,156 0 0
DERMIRA INC COM 24983L104 2,494 92,400 SH   SOLE 92,400 0 0
EBAY INC COM 278642103 1,538 40,000 SH   SOLE 40,000 0 0
EQUIFAX INC COM 294429105 49,189 464,100 SH   SOLE 464,100 0 75,000
FACEBOOK INC CL A 30303M102 331 1,940 SH   SOLE 1,940 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 850 20,800 SH   SOLE 20,800 0 0
FOUNDATION MEDICINE INC COM 350465100 3,646 90,700 SH   SOLE 90,700 0 0
GILDAN ACTIVEWEAR INC COM 375916103 14,789 472,800 SH   SOLE 472,800 0 0
GILEAD SCIENCES INC COM 375558103 234,928 2,899,630 SH   SOLE 2,899,630 0 372,100
GROUPON INC COM 399473107 2,116 407,000 SH   SOLE 407,000 0 0
HANESBRANDS INC COM 410345102 51,512 2,090,600 SH   SOLE 2,090,600 0 289,300
HOLLYFRONTIER CORP COM 436106108 35,739 993,600 SH   SOLE 993,600 0 217,400
ICON PLC SHS G4705A100 2,220 19,500 SH   SOLE 19,500 0 0
IHS MARKIT LTD SHS G47567105 22,282 505,500 SH   SOLE 505,500 0 0
INCYTE CORP COM 45337C102 1,571 13,464 SH   SOLE 13,464 0 0
INFINERA CORPORATION COM 45667G103 2,925 329,800 SH   SOLE 329,800 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 1,877 1,411,832 SH   SOLE 1,411,832 0 0
INTEL CORP COM 458140100 68,362 1,795,231 SH   SOLE 1,795,231 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 1,647 104,500 SH   SOLE 104,500 0 0
JD COM INC SPON ADR CL A 47215P106 71,350 1,867,812 SH   SOLE 1,867,812 0 0
JOHNSON & JOHNSON COM 478160104 4,264 32,800 SH   SOLE 32,800 0 0
JONES LANG LASALLE INC COM 48020Q107 78,374 634,613 SH   SOLE 634,613 0 52,600
LAM RESEARCH CORP COM 512807108 407 2,200 SH   SOLE 2,200 0 0
LEVEL 3 COMMUNICATIONS INC COM NEW 52729N308 15,374 288,500 SH   SOLE 288,500 0 0
LIBERTY GLOBAL PLC SHS CL A G5480U104 366 10,800 SH   SOLE 10,800 0 0
LIVANOVA PLC SHS G5509L101 2,366 33,782 SH   SOLE 33,782 0 0
MELCO RESORT ENTERTAINMENT L ADR 585464100 46,587 1,931,470 SH   SOLE 1,931,470 0 0
MERCK & CO INC COM 58933Y105 1,203 18,800 SH   SOLE 18,800 0 0
MERUS N V COM N5749R100 2,031 102,219 SH   SOLE 102,219 0 0
MICRON TECHNOLOGY INC COM 595112103 943 24,000 SH   SOLE 24,000 0 0
MICROSOFT CORP COM 594918104 1,728 23,200 SH   SOLE 23,200 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 1,955 121,000 SH   SOLE 121,000 0 0
NEWMONT MINING CORP COM 651639106 3,788 101,000 SH   SOLE 101,000 0 0
NIELSEN HLDGS PLC SHS EUR G6518L108 119,920 2,893,140 SH   SOLE 2,893,140 0 348,515
NXP SEMICONDUCTORS N V COM N6596X109 1,074 9,500 SH   SOLE 9,500 0 0
ORACLE CORP COM 68389X105 240,565 4,975,500 SH   SOLE 4,975,500 0 547,728
PAYPAL HLDGS INC COM 70450Y103 195,187 3,048,368 SH   SOLE 3,048,368 0 393,000
PEABODY ENERGY CORP NEW COM 704551100 75,765 2,611,699 SH   SOLE 2,611,699 0 247,600
PERKINELMER INC COM 714046109 2,965 43,000 SH   SOLE 43,000 0 0
PFIZER INC COM 717081103 1,699 47,610 SH   SOLE 47,610 0 0
PROTHENA CORP PLC SHS G72800108 4,015 62,000 SH   SOLE 62,000 0 0
QIAGEN NV SHS NEW N72482123 34,903 1,108,060 SH   SOLE 1,108,060 0 0
QIWI PLC SPON ADR REP B 74735M108 24,446 1,443,139 SH   SOLE 1,443,139 0 335,540
SCHLUMBERGER LTD COM 806857108 108,037 1,548,700 SH   SOLE 1,548,700 0 319,600
SEATTLE GENETICS INC COM 812578102 2,203 40,500 SH   SOLE 40,500 0 0
SINA CORP ORD G81477104 332,387 2,899,151 SH   SOLE 2,899,151 0 126,487
SKYWORKS SOLUTIONS INC COM 83088M102 112,992 1,108,860 SH   SOLE 1,108,860 0 124,300
TECHNIPFMC PLC COM G87110105 220,545 7,899,200 SH   SOLE 7,899,200 0 1,044,000
TIME WARNER INC COM NEW 887317303 760 7,421 SH   SOLE 7,421 0 0
UNITED TECHNOLOGIES CORP COM 913017109 928 8,000 SH   SOLE 8,000 0 0
VERISIGN INC COM 92343E102 595 5,600 SH   SOLE 5,600 0 0
WEIBO CORP SPONSORED ADR 948596101 32,454 328,026 SH   SOLE 328,026 0 0
WYNN RESORTS LTD COM 983134107 203,250 1,364,830 SH   SOLE 1,364,830 0 132,419
XILINX INC COM 983919101 793 11,200 SH   SOLE 11,200 0 0
YANDEX N V SHS CLASS A N97284108 5,321 161,500 SH   SOLE 161,500 0 0